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limb traumas are among the most painful and stressful events , that anybody may experience during his or her life .
so long as pain control is concerned , morphine remains the gold standard for analgesia .
it has been the standard analgesic for many years , and the effects of newer analgesics are often expressed in com... | background : we assessed the effects of low - dose iv ketamine - midazolam versus morphine on pain control in patients with closed limb fracture(s ) ; and also compared the incidence of adverse events ( cardio - pulmonary ) between two groups.materials and methods : this prospective , single - blind , non - inferiorit... | INTRODUCTION
MATERIALS AND METHODS
Study procedures and outcome measure
Study design and Patients
Study analysis
RESULTS
DISCUSSION AND CONCLUSIONS
Limitations
CONCLUSIONS
AUTHOR'S CONTRIBUTIONS |
a pregnant 23-year - old female with a six - year history of type 1 diabetes presented with a complaint of increased blur in both eyes for the previous two months .
best corrected visual acuity was 20/40 ou . slit - lamp examination was entirely unremarkable in both eyes .
dilated funduscopic examination was signific... | we present a case of diabetic macular edema in a pregnant patient treated with a single intravitreal injection of triamcinolone acetonomide .
initial presentation and serial examinations after treatment included visual acuity , slit - lamp examination , indirect ophthalmoscopy , and optical coherence tomography .
... | Case report
Discussion |
it is the most frequent cause of acute liver failure when acetaminophen overdose is included and is therefore medically relevant , exhibiting a high morbidity and mortality .
it is also of economic importance and represents the second most frequent cause for drug withdrawal from the pharmaceutical market .
many agents ... | drug - induced liver injury ( dili ) is a potentially fatal adverse event with significant medical and economic impact .
many drugs , especially anti - infective , neurologic or pain - modifying substances , act as hepatotoxins . with cardiovascular toxicity ,
liver toxicity is one of the two leading causes for dr... | Introduction
Diagnosing DILI: future biomarkers
Management and outlook
Disclosures |
need can be defined as whatever is required for health or comfort ; though there are various ways to look at it as normative , felt , expressed , fundamental , etc .
a person with psychiatric disorder needs all things that anybody needs to lead a good life .
a person 's need at a given point of time is likely to be i... | background : female patients hospitalized for a long duration in psychiatric hospitals are a special population with unique needs.aims and objectives : to assess rehabilitation needs of chronic female inpatients attending psychiatric rehabilitation services in a tertiary care psychiatric hospital.materials and methods... | INTRODUCTION
Aim
MATERIALS AND METHODS
Interview schedule
Sample
RESULTS
DISCUSSION
Limitations
CONCLUSION
Financial support and sponsorship
Conflicts of interest |
guidelines would be the syntheses of the best available evidences , in addition to professional judgment and patient preferences , support decision - making by clinicians , managers and policy makers about the organization , delivery and improvement of health care [ 1 - 8 ] . according to the world health organization ... | backgroundguidelines have produced and used in complex environment of health care system with its ethical , economical , legal and other aspects ; that should be taken into account in any country .
modifying the format and content of guidelines might facilitate their usage and lead to improved quality of care and co... | Introduction
Materials and Methods
Results
Discussion
Conclusion |
orthognathic surgery can affect the oropharyngeal airway through skeletal displacement and changes in the positions of the hyoid bone and tongue1 .
the main concern regarding pharyngeal dimensional changes caused by orthognathic surgery is patient sleep quality1 .
up to 25% of adults suffer from obstructive sleep apnea... | objectivesany change in maxilla and mandible position can alter the upper airway , and any decrease in the upper airway can cause sleep disorders .
thus , it is necessary to assess airway changes after repositioning of the maxilla and mandible during orthognathic surgery .
the purpose of this study was to evaluate... | I. Introduction
II. Materials and Methods
1. Participants
2. Inclusion criteria
3. Exclusion criteria
4. Imaging procedure
5. 2D and 3D
6. Data analysis
III. Results
IV. Discussion
V. Conclusion |
palatal tremor is a rare movement disorder characterized by rhythmic contraction of the soft palate .
palatal tremor is most often symptomatic , secondary to brainstem or cerebellar disease and , in rarer cases , is categorized as essential in the absence of documented brain lesions.1 some authors have documented hyper... | palatal tremor is a rare movement disorder characterized by rhythmic contractions of the soft palate .
it is most often symptomatic , secondary to brainstem or cerebellar disease and , in rarer cases , is categorized as essential in the absence of documented brain lesions .
there have also been reports in the lite... | Introduction
Case report
Discussion |
clinical clues apparent on examination can expand or narrow the differential diagnosis substantially , even when the patient is seen first for management of a life - threatening condition in the intensive care unit ( icu ) .
we present a female patient with presumed chronic inflammatory demyelinating polyneuropathy ( c... | we present a female patient who was referred for management of respiratory failure . she was being evaluated and managed as worsening chronic inflammatory demyelinating polyneuropathy with type 2 respiratory failure .
initial examination showed hypertrichosis , clubbing and papilledema along with severe distal and p... | Introduction
Case Report
Discussion |
however , there are several controversies in the operative indication , surgical approach and the best treatment method .
the gold standard in the treatment of distal radius fracture remains uncertain.1 cast treatment with or without closed reduction has long been considered a viable option for treatment of distal radi... | background : fractures of distal radius are common injury in all age groups . cast treatment with or without close reduction is a viable option .
however , the results are often unsatisfactory with restricted function .
the open reduction and internal fixation often results in extensive soft tissue dissection and ... | I
M
Operative procedure
R
D |
insulin plays a critical role in glucose homeostasis by regulating the balance between glucose production by the liver and glucose uptake by muscle and adipose tissues . in adipocytes and myocytes
, insulin regulates glucose transport by controlling the translocation of the glucose transporter , ( glut)4 .
ir has a rat... | metabolic syndrome ( mets ) is a cluster of cardiovascular risk factors that includes obesity , diabetes , and dyslipidemia .
accumulating evidence implies that mets contributes to the development and progression of alzheimer 's disease ( ad ) ; however , the factors connecting this association have not been determi... | Metabolic syndrome and insulin signaling
Insulin signaling in the brain
MetS and AD
IR and tau
IR and A
Insulin signaling as a therapeutic target of AD
Conclusion |
studies that only infuse oxytocin into participants and then make claims about human behavior are suspect .
this approach does not identify what the brain itself is doing during social interactions , including neurochemical promotion and inhibition of oxytocin synthesis and dose - response relationships between oxytoci... | editor s note : the man behind the discovery of the behavioral effect of a neurochemical in the brain called oxytocin wondered if the molecule might motivate people to engage in cooperative behaviors . in a series of tests using videos
, his lab discovered that compelling narratives cause oxytocin release and have t... | Provoking the Brain
Narrative Immersion
Attention-getting
Do We Know a Good Story When We See One? |
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