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recent years were associated with substantial development of enteral nutrition , and particularly , home enteral nutrition ( hen ) . for the last ten to 20 years , hen has been fully reimbursed in many european countries which has contributed to increased popularity of this treatment modality [ 8 , 13 ] . also , in po...
published epidemiologic data on the administration rates of enteral / parenteral home nutrition is very limited . the aim of this first nationwide study was to assess the availability of pediatric home enteral nutrition ( hen ) services in poland . the questionnaire was sent to all regional centers providing pedia...
Introduction Materials and methods Results Discussion
wild - type and rpa12 cells were grown to stationary phase in a synthetic complete medium . we used microarrays to study the effect of rpa12 deletion on the cellular metabolism of yeast and identified that distinct class of genes were up - regulated in rpa12 strain . yeast wild - type and deletion strains : eurosca...
the ribosomal rna ( rrna ) biosynthesis is the most energy consuming process in all living cells and the majority of total transcription activity is dedicated for synthesizing rrna . the cells may adjust the synthesis of rrna with the availability of resources . rrna is mainly synthesized by rna polymerase i that ...
Direct link to deposited data Experimental design, materials and methods Experimental design Materials Sample preparation Statistical analysis of the microarray data Results
muscle strength exercise is an important therapeutic technique in physical therapy , which is often performed for recovery from disuse atrophy . although the precise mechanism of satellite cell activation induced by hepatocyte growth factor ( hgf ) is unclear , it is one of the key events in this recovery process...
[ purpose ] the present study aimed to determine the effects of short muscle strength exercise on hepatocyte growth factor expression and satellite cell activation . [ subjects ] the study included 72 212-week - old male sprague - dawley rats . [ methods ] the rat plantaris muscle was contracted with a 5-min...
INTRODUCTION SUBJECTS AND METHODS RESULTS DISCUSSION
from october 1996 to november 2002 , 30 consecutive patients with hepatocellular carcinomas underwent transarterial chemoembolization followed by hepatic resection at our institution . of these patients , we included the patients who met the two following criteria : ( a ) two or more four - phase ( i.e. , hepatic arter...
objectivethe purpose of our study was to assess whether a review of multiphasic helical ct combined with the previous serial ct images could be helpful to depict a viable tumor in hepatocellular carcinoma treated with transarterial chemoembolization.materials and methodstwenty - four consecutive patients with 35 hepat...
MATERIALS AND METHODS Patient Selection Multiphasic Helical CT Transarterial Chemoembolization Techniques Pathologic Analysis Image Analysis Statistical Analysis RESULTS DISCUSSION
this narrowing can lead to entrapment of the nerve roots and to neurogenic claudication , i.e. pain in the lower extremities while walking or standing . degenerative lumbar spinal stenosis is the most common reason for lumbar surgery in patients beyond the age of 65 years . the standard surgical management for degen...
degenerative lumbar spinal stenosis is the most common reason for lumbar surgery in patients in the age of 65 years and older . the standard surgical management is decompression of the spinal canal by laminectomy and partial facetectomy . the effect of this procedure on the shear strength of the spine has not yet...
Introduction Methods Specimens and specimen preparation Biomechanical testing procedure Analysis Results Discussion
spinal injuries in small children are rare with a reported incidence of 0.2 to 0.5% of all fractures or dislocations and 1.5 to 3% of all lesions in the spine.1 it has been shown that the younger the child at the time of injury , the more likely the upper cervical spine is affected , with over 50% of spinal injuries in...
study design case report . objective odontoid process fractures represent an uncommon injury in small children , with their optimal management remaining unclear . we present a case of conservatively managed displaced type 2 odontoid process fracture in a small child . methods we analyzed clinical and ra...
Introduction Case Report Discussion
chronic graft versus host disease ( cgvhd ) belongs to the most serious and frequent ( 3070% ) complications in patients undergoing hemopoietic stem cells transplantation ( hsct ) for hematological malignancies . musculoskeletal and skin cgvhd , by inducing fibrotic changes in tissues , may result in reduction of joint...
chronic graft versus host disease ( cgvhd ) is a frequent complication of allogeneic stem cell transplantation . extensive musculoskeletal and skin involvement may induce severe functional impairment , disability and quality of life deterioration . physical rehabilitation is recommended as ancillary therapy in the...
INTRODUCTION CASE REPORT DISCUSSION
complex regional pain syndrome ( crps ) type ii , known as causalgia , develops after a nerve injury , and tends to show the more painful and more severe symptoms of crps . the ordinary strategy in crps treatment is often multi - disciplinary , with the use of various kinds of medications and physical therapies combine...
complex regional pain syndrome ( crps ) type ii is a syndrome that develops after nerve injury . symptoms may be severe , and vary depending on the degree of sympathetic nerve involvement . as yet , there is no satisfactory treatment . we report the case of a female patient who had an l5 left transverse process ...
INTRODUCTION CASE REPORT DISCUSSION CONCLUSION
the prevalence of childhood overweight and obesity gradually increases , even in preschool - age children . globally , more than 20 million children who are below the age of 5 are overweight . the finding that overweight in preschool children is an indicator of five times more overweight in adolescence and four times m...
waist circumference , a proxy measure of abdominal obesity , is associated with cardio - metabolic risk factors in childhood and adolescence . although there are numerous studies about waist circumference percentiles in children , only a few studies cover preschool children . the aim of this study was to develop a...
Introduction Materials and methods Subjects Measurements Statistical analysis Results Discussion
these cells normally line body cavities , specifically pleura , peritoneum , pericardium , and testis . they can be localized or diffuse . initially it occurred in miners and millworkers who were directly exposed to asbestos in their work environment . subsequently , mesothelioma was diagnosed in plumbers , carpenters ...
introduction . malignant pleural mesothelioma ( mpm ) is an aggressive cancer arising from pleural mesothelium . surgery aims to either cure the disease or control the symptoms . two surgical procedures exist : extrapleural pneumonectomy ( epp ) and pleurectomy / decortication ( p / d ) . in this systematic re...
1. Introduction 2. Methods 3. Results 4. Discussion: Current and Future Research 5. Conclusion
an intracranial arachnoid cyst ( iac ) is a developmental brain disorder in which fluid accumulates within a split of the arachnoid membrane . these structures do not fit the anatomical definition of a cyst and should be referred to as pseudocysts or diverticula . however , we have adopted the widely used term arachno...
arachnoid cysts are defined as an accumulation of fluid within the arachnoid membrane . feline intracranial arachnoid cysts are seldom reported , with only three cases in the veterinary literature . a 1-year - old male neutered european cat with a 24 h history of seizures was presented to the small animal neurolog...
Introduction Case description Discussion Conclusions
intraperitoneal lymphangioma ( il ) is a type of benign cyst with an incidence of approximately 1% . lesions often take place in mesentery , retroperitoneum . most previously reported ils are asymptomatic and are often incidentally found through imaging investigation or during surgery for other unrelated causes . curre...
background : intraperitoneal lymphangioma ( il ) used to be thought of as a benign lymphatic malformation with a low rate of preoperative diagnosis . this retrospective study aimed to explore the connection between the cysts and clinical manifestation and imaging characteristics , and to study diagnostic confusion ,...
I M Statistical analysis R D Location and histological type Symptoms Imaging examination and diagnosis Therapy and recurrence Financial support and sponsorship Conflicts of interest
the database , danbio , is a nationwide , danish register for research use in rheumatologic diseases such as rheumatoid arthritis ( ra ) , axial spondyloarthritis ( ax spa ) , and psoriatic arthritis ( psa ) . it also serves as a clinical database that monitors clinical quality of treatment by the use of selected quali...
introductiondanbio is a research register and a data source for rheumatologic diseases ( rheumatoid arthritis [ ra ] , axial spondyloarthritis , and psoriatic arthritis ) for monitoring clinical quality at the national , regional , and hospital levels.study populationthe register includes patients with rheumatologic d...
Introduction Study population and data collection Main variables Follow-up Quality indicators Examples of research Administrative issues and funding Conclusion
stereotactic body radiotherapy ( sbrt ) for non - surgical treatment of early - stage primary lung cancer has recently been investigated in clinical practice , during which several problems regarding lung cancer treatment planning have been identified [ 15 ] . the development of 4d - computed tomography ( ct ) has made...
the purpose of this study was to validate the dose prescription defined to the gross tumor volume ( gtv ) 3d and 4d dose distributions of stereotactic radiotherapy for lung cancer . treatment plans for 94 patients were generated based on computed tomography ( ct ) under free breathing . a uniform margin of 8 mm wa...
INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION CONCLUSION
new - onset atrial fibrillation ( noaf ) in the context of acute myocardial infarction ( ami ) is common and usually induces severe hemodynamic dysfunction and has been shown to be an independent predictor of mortality among ami patients . in addition , among the patients complicated with noaf , the incidence of stroke...
background : recent observational studies have shown that patients with higher killips score ( > i ) have higher risk of new - onset atrial fibrillation ( noaf ) following acute myocardial infarction ( ami ) , while others drew a neutral conclusion . the ultimate predictive value of high killips class on noaf remain...
I M Inclusion criteria Search strategies Quality assessment Data extraction Definition of important parameters Statistical analysis R D Limitations
nearly all of the photoactive iridium(iii ) complexes that are used as emitters in electroluminescent devices , as dyes in solar cells , in nonlinear optics ( nlo ) , as photoredox catalysts , as solar fuels , and in bioimaging contain conjugated five - membered chelated ligands , such as the commonly used 2-phen...
a new family consisting of three luminescent neutral ir(iii ) complexes with the unprecedented [ ir(c^n^c)(n^n)cl ] architecture , where c^n^c is a bis(six - membered ) chelating tridentate tripod ligand derived from 2-benzhydrylpyridine ( bnpy ) and n^n is 4,4-di - tert - butyl-2,2-bipyridine ( dtbubpy ) , ...
Introduction Results and Discussion Conclusions Experimental Section
pain is highly prevalent in older people and is associated with depression , falls , poor quality of life , sleep disturbance , mobility limitation and decline in physical function [ 1 , 2 ] . the prevalence of pain doubles from 2 years to 1 month before death . up to two - thirds of people with advanced cancer repor...
backgroundpain management can be challenging in frail older people with cancer due to drug drug interactions and heightened susceptibility to adverse drug events.objectiveto investigate the relationship between analgesic use and pain by frailty status in older outpatients with cancer.methodsa total of 385 consecutive...
Introduction Methods Study Population and Data Collection Measures and Definitions Statistical Analysis Ethical Considerations Results Discussion Strengths and Limitations Conclusions
in addition to being the first cause of mortality for persons under the age of 45 , injury represents the disease with the highest financial burden . furthermore , the demographic shift along with the incessant development of new and costly technologies have led to an explosion in the costs of trauma care.[13 ] in the ...
background : indicators of structure , process , and outcome are required to evaluate the performance of trauma centers to improve the quality and efficiency of care . while periodic external accreditation visits are part of most trauma systems , a quantitative indicator of structural performance has yet to be propose...
INTRODUCTION MATERIALS AND METHODS Study population Data Accreditation data Patient-level data Development of the structural performance indicator Validation of the structural performance indicator Sensitivity analyses RESULTS Sensitivity analyses DISCUSSION Strengths and limitations CONCLUSION
angiosarcomas are poorly differentiated neoplasms composed of stands of endothelial cells and have a very narrow lumen filled with blood cells . angiosarcomas frequently originate from the vascular wall , usually from medium and large sized veins . they are malignant but rarely result in recurrences or metastases to lu...
hemangioendotheliomas are poorly differentiated neoplasms built from strands of endothelial cells and have a very narrow lumen filled with blood cells . hemangioendotheliomas are commonly detected during the initial six months of life , concerning mainly soft tissues and skin . it is the most common bening liver c...
Introduction Case report Discussion None
large - scale clinical trials have created a robust evidence base to inform much of what is now standard acute - stroke practice.13 the classical clinical trial is designed to test efficacy of a particular intervention over a comparator , for example , placebo or usual care . to facilitate comparison between the grou...
as stroke care has developed , there has been a need to robustly assess the efficacy of interventions both at the level of the individual stroke survivor and in the context of clinical trials . to describe stroke - survivor recovery meaningfully , more sophisticated measures are required than simple dichotomous end ...
Why measure functional outcomes in stroke trials? Which functional measure to use Clinimetric properties of scales National Institutes of Health Stroke Scale Barthel Index Modified Rankin Scale Quality of life Conclusion
allogeneic hematopoietic stem cell transplantation ( allo - hsct ) is an established treatment for hematologic malignancy , and more than 15,000 procedures are performed worldwide each year . after hsct , chronic graft - versus - host disease ( cgvhd ) is the most common cause of morbidity and mortality . indeed , the ...
nephrotic syndrome ( ns ) rarely occurs after hematopoietic stem cell transplantation ( hsct ) as a late manifestation of graft - versus - host disease ( gvhd ) . herein , we report a case of hsct - associated membranous nephropathy in a female patient with aplastic anemia . the patient received an allogeneic hsct...
Introduction Case report Discussion Conflict of interest
re - expansion pulmonary oedema ( repe ) is a rare complication after re - inflation of a chronically collapsed lung , following pneumothorax or effusion . it has an incidence of about 1% , but is associated with high mortality ( 20% ) . re - expansion pulmonary oedema is usually ipsilateral and the risk is highest aft...
re - expansion pulmonary oedema ( repe ) is a rare complication following re - inflation of a chronically collapsed lung , which is often fatal . we present a case of a 22-year - old male who presented to the hospital with severe respiratory distress and a history of blunt abdominal trauma 3 months back . he was dia...
INTRODUCTION CASE REPORT DISCUSSION CONCLUSION
early childhood caries is a significant public health problem in both developing and industrialized countries which continues to affect babies and preschool children worldwide . early childhood caries ( ecc ) is not life - threatening but it may contribute to suboptimal health and failure to thrive . ecc is a chronic ,...
background : dental caries among preschool children is still a major public health problem in many developing countries including india . hence the aim of the present study was to find out the prevalence of early childhood caries among 3 - 5 year old pre - schoolers in schools of marathahalli , bangalore.materials and...
INTRODUCTION MATERIALS AND METHODS RESULTS DISCUSSION CONCLUSION
a 36-year - old woman with no history of any trauma exhibited a palpable mass on the volar ulnar aspect of her left middle finger at the level of the distal interphalangeal joint for a year . physical examination revealed a 11.5-cm hard , non - tender , non - movable mass . plain radiographs of the finger revealed a ca...
calcifying aponeurotic fibroma is a rare soft tissue tumor that occurs in the distal extremities of children and adolescents . we report ultrasound and x - ray findings of a calcifying aponeurotic fibroma in the finger of a 36-year - old woman , associated with distal phalangeal bone involvement .
CASE REPORT DISCUSSION
more than half of the benign tumors are myxomas , and the rest are lipomas , papillary fibroelastoma , and rhabdomyomas . sarcoma ( including angiosarcoma , undifferentiated sarcoma , malignant fibrous histiocytoma , leiomyosarcoma , and osteosarcoma ) is the most often reported neoplasm occupying 95% of malignant card...
backgroundprimary cardiac tumors are rare but have favorable surgical prognosis . previous studies have been small series studies with limited surgical approaches . to date , few studies have examined the clinical features associated with different surgical procedures.material/methodsin a search of the cardiovascu...
Background Material and Methods Patient selection Data recording Data analysis Statistical analysis Results Patient characteristics Patient symptom Lesion characteristics Operation information Conventional versus minimally invasive procedure Discussion Conclusions
the gag reflex is a physiological response which safeguards the airway from foreign bodies . gagging can become a conditioned response that makes dental treatment difficult or impossible for both the individual and the dentist . clinicians successfully treat many patients with mild gagging problems using only m...
abstractbackgroundgagging can become a conditioned response that makes dental treatment difficult or impossible for both the individual and the dentist . the aim of this study is to report a 50 year old female and two children ( 15 and 11 years old ) with exaggerated gag reflex referred to faculty of dentist...
INTRODUCTION CASE DESCRIPTION AND RESULTS DISCUSSION CONCLUSIONS ACKNOWLEDGMENTS AND DISCLOSURE STATEMENTS
affective disorders are a leading cause of disabilities worldwide , and the etiology of these many affective disorders such as depression and posttraumatic stress disorder ( ptsd ) is due to hormone changes , which includes hypothalamus - pituitary - adrenal ( hpa ) axis in the peripheral nervous system and neuromodula...
affective disorders are a leading cause of disabilities worldwide , and the etiology of these many affective disorders such as depression and posttraumatic stress disorder is due to hormone changes , which includes hypothalamus - pituitary - adrenal axis in the peripheral nervous system and neuromodulators in the cent...
1. Introduction 2. NE and Stress 3. NE and Emotions 4. Stress Induced Emotional Flows 5. Typical Mental Disorders 6. Conclusions
more than 200 million people suffer from chronic obstructive pulmonary disease ( copd ) worldwide , and three million of them die each year.1 thereby , copd is the fourth most common cause of death globally . copd consists of both bronchial disease and emphysema , with the latter leading to enlargement of the airspaces...
there is a need for efficient techniques to assess abnormalities in the peripheral regions of the lungs , for example , for diagnosis of pulmonary emphysema . considerable scientific efforts have been directed toward measuring lung morphology by studying recovery of inhaled micron - sized aerosol particles ( 0.41.5 ...
Introduction Deposition of nanoparticles in diseased lungs Breathing maneuver in ADAM and AiDA Assessment of airspace dimensions from particle recovery Relationships between particle loss and the morphology of terminal bronchioles and gas-exchange region AiDA as a diagnostic tool Summary and conclusion
in a previous issue of critical care , nseir and colleagues presented an article regarding continuous control of endotracheal cuff pressure and tracheal wall damage . among the pathogenic mechanisms responsible for ventilator - associated pneumonia ( vap ) , oropharyngeal colonization by potentially pathogenic microorg...
continuous control of tracheal tube cuff inflation using a pneumatic device resulted in severe tracheal wall damage in ventilated piglets . this damage was similar in piglets managed with manual control of cuff inflation . the periodic hyperinflation of the tube cuff used in both groups of this study may explain t...
None Abbreviations Competing interests Acknowledgements
stroke is the leading cause of adult disability in the developed world.1 , 2 in ischemic stroke , a blood clot ( thrombus ) leads to an area of brain experiencing a significant drop in cerebral blood flow , which can ultimately result in death of this hypoperfused tissue . collateral blood flow gives rise to the ischem...
the cornerstone of acute ischemic stroke treatment relies on rapid clearance of an offending thrombus in the cerebrovascular system . there are various drugs and different methods of assessment to select patients more likely to respond to treatment . current clinical guidelines recommend the administration of intr...
Introduction Thrombus formation and fibrinolysis Thrombolytic drugs Enhancing thrombolysis delivery
zr - labeled monoclonal antibodies ( mabs ) have recently been useful in clinical trials for positron emission tomography ( pet ) imaging of various cancers due to the favorable pairing of the radioisotope s half - life ( t1/2 = 3.3 days ) and the antibody s pharmacokinetic properties , complemented by the hi...
pertuzumab is a monoclonal antibody that binds to her2 and is used in combination with another her2specific monoclonal antibody , trastuzumab , for the treatment of her2 + metastatic breast cancer . pertuzumab binds to an her2 binding site distinct from that of trastuzumab , and its affinity is enhanced when...
Introduction Materials and Methods Results Discussion Conclusions
data on case investigation timelines in 2002 were collected from records at state and local health departments and public health laboratories in each of 6 states for < 100 salmonella spp . participating states included 1 with a large population ( > 6 million ) , 3 with a medium - sized population , and 2 with a small (...
we reviewed timeline information for a sample of salmonella spp . , shigella spp . , campylobacter spp . , and escherichia coli o157:h7 cases and all confirmed foodborne outbreaks reported in 6 states during 2002 . increasing the timeliness of case follow - up , molecular subtyping , and linkage of results are c...
The Study Conclusions
she presented with a 5-day history of behavioral change , in the form of incomprehensive talking visual and auditory hallucinations , and short attention span . she had sleep disturbance , labile mood , and decreased appetite with loss of sphincter control . one month prior to this episode , she had one attack of unpro...
new - onset psychosis in children represents a complex presenting symptom . psychosis can be attributable to a combination of factors and etiologies , and all possible causes must be systematically examined . there is growing evidence that a proportion of psychosis / psychiatric manifestations in children may be i...
Case Report Patient 1 Patient 2 Patient 3 Discussion
within and beyond the world of nanoscience , images abound . there are lots of colourful images of structures at the nanoscale , based on visualizations of digital data created by scanning probe microscopy or other imaging instruments ( as are made available to colleague nanoscientists ) . there are also artist s impre...
images , ranging from visualizations of the nanoscale to future visions , abound within and beyond the world of nanotechnology . rather than the contrast between imaging , i.e. creating images that are understood as offering a view on what is out there , and imagining , i.e. creating images offering impressions of how...
Introduction Imag(in)ing the Invisible Nanoscale Practices of Entangling the Future and the Present Entanglements of Nanoscience and Arts Images Standing for Nanotechnology In Conclusion
neuromyelitis optica ( nmo ; formerly known as devic disease ) is an inflammatory demyelinating disease of the central nervous system which is characterized by severe relapsing episodes of transverse myelitis and optic neuritis . in the early stages , other parts of the central nervous system are spared , but we now kn...
we present the unusual case of a patient with an aquaporin 4 antibody - seropositive neuromyelitis optica spectrum disorder who presented with autonomic dysregulation , cognitive impairment , and symptoms of psychosis . only a few previous cases have been described with similar psychiatric symptoms . brain mri sho...
Background Case Presentation Discussion Statement of Ethics Disclosure Statement
until recently , primary headaches such as migraine and cluster headache ( ch ) were described as vasomotor headaches . initial positron emission tomography ( pet ) images shed light on the origins of these syndromes , documenting activation in the mesencephalic and pons regions for migraine , and in the grey hypothala...
we have investigated the cerebral activation centre in four patients with episodic cluster headache ( ch ) with functional magnetic resonance imaging ( f - mri ) . the patients underwent mri scans for anatomical and functional data acquisition in the asymptomatic state , during a headache attack and after subcutaneo...
Introduction Materials and methods Study design Data acquisition Pre-processing of MRI data Results Discussion
parental obesity increases the risk of obesity in offspring through genetic , biological , and environmental influences [ 13 ] . maternal obesity , weight gain , and increased body mass index ( bmi ) between pregnancies and gestational diabetes increase risks of offspring obesity , type 2 diabetes mellitus ( t2 dm ) , ...
background . maternal obesity , excess weight gain and overnutrition during pregnancy increase risks of obesity , type 2 diabetes mellitus , and cardiovascular disease in the offspring . maternal biliopancreatic diversion is an effective treatment for severe obesity and is beneficial for offspring born after mater...
1. Introduction 2. Material and Methods 3. Results 4. Discussion 5. Conclusion
in order to determine whether the microprocessor is involved in the processing of cellular rnas ( other than mirnas ) that contain hairpin structures , we focused on the identification of endogenous rna targets of dgcr8 . for this , we used the cross - linking immunoprecipitation protocol coupled to high - throughput s...
the drosha - dgcr8 complex ( microprocessor ) is required for microrna ( mirna ) biogenesis . dgcr8 recognizes the rna substrate , whereas drosha functions as the endonuclease . high - throughput sequencing and crosslinking immunoprecipitation ( hits - clip ) was used to identify rna targets of dgcr8 in human cell...
RESULTS HITS-CLIP identifies novel targets of the Microprocessor The Microprocessor regulates the abundance of MALAT1 DGCR8 regulates snoRNA stability independently of Drosha The Microprocessor cleaves the mRNA of protein-coding genes Modulation of alternative spliced isoforms by the Microprocessor DISCUSSION Supplemen...
recently , the focus of management in schizophrenia has been shifting to early detection and intervention of the disorder . the primary prevention is to eliminate etiological risk factors or to strengthen individual resistibility to the morbid risk ; however , these have not been shown to be effective in schizophrenia ...
to investigate the gender difference of early symptoms appearing before the onset of the psychotic symptoms in patients with first - episode schizophrenia , we reviewed the medical records of 63 patients ( 38 males , 25 females ) , who were hospitalized for first - episode schizophrenia . the frequency and duration ...
INTRODUCTION MATERIALS AND METHODS Subjects Assessments Statistical analysis RESULTS DISCUSSION
the dynamics of the diabetes and hyperlipidemia are changing rapidly in low- to middle - income countries . in 2030 the number of adult with impaired glucose tolerance may rise from 344 million ( 2010 ) to 472 million by 2030 . international diabetes federation ( idf ) estimated that 80% of world diabetic population li...
objective : to study the antidiabetic and antihyperlipidemic effects of an ethanolic extract of the whole plant of tridax procumbens ( asteraceae ) in streptozotocin - induced diabetic rats.materials and methods : the whole plant of t. procumbens was collected in different regions of madurai districts , tamil nadu . ...
Introduction Materials and Methods Plant collection Extraction of leaves Animals Chemicals and reagents Phytochemical screening Anti-diabetic screening of ethanolic extract of whole plant of Biochemical analysis: Statistical analysis Result Discussion Conclusion
the first macroscopic description of tg belongs to merkel , followed and extended by krause and schaffer . the authors report that the tg composition is characterized by ganglion cells ( pseudounipolar neurons ) , satellite cells and their appendages . histological preparations visualize that the perikarya of the pse...
the trigeminal ganglion ( tg ) , a cluster of pseudounipolar neurons , is located in the trigeminal impression of the temporal pyramid . it is covered by a sheath of the dura mater and arachnoid and is near the rear end of the cavernous sinus . the peripheral processes of the pseudounipolar cells are involved in t...
Introduction Materials and methods Results Lightmicroscopic study of the trigeminal ganglion Discussion Large light neurons Medium-sized neurons Small neurons
cellular allograft rejection is one of the commonest causes of graft dysfunction in the early as well as late posttransplant period . chemokines induce migration of lymphocytes bearing specific chemokine receptors , which is central to allograft rejection , as has been emphasized in many experimental and human studies....
allospecific recruitment of t cells is primary to the pathogenesis of renal transplant rejection . chemokines and their receptors inducing a th1 cytokine response play a central role in this recruitment . renal allograft biopsies of 28 patients with acute cellular rejection and 10 protocol biopsies ( controls ) we...
Introduction Subjects and Methods Immunohistochemistry Results Distribution of CC chemokine receptor 5-positive cells and histopathologic correlations Clinical correlations Discussion
edible plants ( 100 g ) were minced into 5 mm fragments and extracts were obtained with methanol ( 200 ml ) overnight at room temperature . the extracts were filtered and the residue was re - extracted under the same conditions as above . the combined filtrates were evaporated in a vacuum slightly below 40c in a rotary...
background : in diabetic populations , endogenous secretory receptor for advanced glycation end products ( esrage ) levels may be related to the degree of diabetic complications or to the protection from diabetic complications.objective:we investigated the impact of 29 methanolic extracts from edible plants on esrage ...
Materials and Methods Preparation of methanolic extracts from 29 edible plants Cell culture Measurement of endogenous secretory receptor for advanced glycation end products concentrations in culture media Measurement of 8-hydroxydeoxyguanosine in human umbilical vein endothelial cells DNA Measurement of peroxynitrite l...
over - the - counter ( otc ) and prescription drug misuse are the nonmedical use of medication , which is used without a prescription or for the feeling caused by the drug . otc and prescription drugs are fast becoming the drugs of choice for adolescents , with the national center on addiction and substance abuse rep...
parent and peer disapproval were examined as potential predictors of recreational use of over - the - counter ( otc ) and prescription pain medication . risk perception was studied as a potential mediator of the effects of parent and peer disapproval . four hundred and sixty - five college students ( mage = 18.57 ...
1. Introduction 2. Methods 3. Results 4. Comments/Discussion
the first case occurred in a 40-year - old woman from kuranda , queensland , with a 1-week history of fever , myalgia , headache , and dry cough . a provisional diagnosis of leptospirosis was made , and she was treated with intravenous penicillin . urea and creatinine levels continued to increase over 3 days to 14.8 mm...
we report 3 cases of spotted fever group rickettsial infection ( presumed queensland tick typhus ) in residents of northern queensland , australia , who had unusually severe clinical manifestations . complications included renal failure , purpura fulminans , and severe pneumonia . clinical illness caused by ricketts...
The Cases Case 1 Case 2 Case 3 Conclusions
breast cancer is a leading cause of mortality and morbidity all over the world . in 2008 , close to 1.4 million cases were diagnosed with breast cancer worldwide . the incidence varies among different populations with high rates seen in developed countries compared to developing countries [ 2 , 3 ] . in general , breas...
introduction . there is an established fact that asian breast cancer patients are , on average , younger than their european counterparts . this study aimed to utilize the data from the cancer incidence in five continents i through xiii ( published by the international agency for research on cancer ) to examine ...
1. Introduction 2. Material and Methods 3. Results 4. Discussion 5. Conclusion
reversible phosphorylation of serine , threonine , and tyrosine residues is one of the most common and important regulatory posttranslational modifications of proteins and plays a crucial role in many biological processes , including cellular signal transduction , regulation of enzyme activities , metabolic regulation ...
selecting an appropriate matrix solution is one of the most effective means of increasing the ionization efficiency of phosphopeptides in matrix - assisted laser - desorption / ionization time - of - flight mass spectrometry ( maldi - tof - ms ) . in this study , we systematically assessed matrix combinations of 2 , 6...
1. Introduction 2. Experimental 3. Results and Discussion 4. Conclusion
epidemiological studies have established that periodontitis is a risk factor for cardiovascular diseases , lung diseases , renal diseases , and low birth weight in children . accordingly , it may be assumed that dental plaque bacteria not only influence the oral cavity locally , but may also contribute to the developme...
over the last two decades , the amount of evidence corroborating an association between dental plaque bacteria and coronary diseases that develop as a result of atherosclerosis has increased . these findings have brought a new aspect to the etiology of the disease . there are several mechanisms by which dental pla...
1. Introduction 2. Periodontitis 3. Atherosclerosis 4. Dental Plaque Bacteria and Atherosclerotic Processes 5. Conclusion
heart failure is a chronic , progressive disease affecting approximately 12% of all the adult population , increasing to more than 10% in the population segment over 70 years ; its incidence rose with the extension of life - span and the aging of the population [ 13 ] . its prognosis is poor , the mortality is higher t...
heart failure is a chronic , progressive disease in which the overexpression of biologically active molecules and neurohomonal activation are the key factors of the evolution and natural history . the apelin - apj system is a newly discovered molecular pathway and the raas counterbalance is its principal effect . ...
Introduction Physiological effect of apelin/APJ receptor pathway on the cardiovascular system The role of apelin/APJ system in heart failure Experimental animal studies Human studies Conclusions
diabetes mellitus is the most common metabolic disease and becomes a heavy burden of public health systems . in china , deterioration of beta cell function and insulin resistance are two fundamental pathophysiologic defects of type 2 diabetes mellitus ( t2 dm ) . it has been proven that at the time when t2 dm was estab...
the objective of this paper is to investigate the effects of liraglutide in combination with short - term continuous subcutaneous insulin infusion ( csii ) therapy on glycemic control and beta cell function in patients with newly diagnosed type 2 diabetes mellitus ( t2 dm ) . thirty - nine eligible newly diagnosed t...
1. Introduction 2. Subjects and Methods 3. Statistical Analyses 4. Results 5. Safety Issues 6. Discussion