id int64 | subtask string | question string | options list | answer_index int64 | answer_text string | metadata string |
|---|---|---|---|---|---|---|
1 | 5_tfbs | I need to know if ZBTB33 is likely to bind to this DNA fragment: CAGGCACAAACTTTGTGCGAGCGCGCCCCCTCTGCCTCGCGCGCGCGCTCACACCCGCCTGGCAACCACCTGACACGCTGATGCTGGCGGCTGCAGGAAA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "ZBTB33", "true_labels": ["ZBTB33", "EGR1", "NRF1"]} |
2 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CTTGTCTCCTTTTGCTTCCCAAGGGGTCAGACTGTGTGCGTTGAGGCCCTGAGGGCGCCCCACCGTAGCGCTGCGCAGGTGTGCACGCACACACGCTCCC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
3 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CACAGTTCTTCATCCACACGCCATTTCCTCTCTGCCCTTCTTTGTACCAAAGATCACTGTGTCCAAGAAAAGCATTCTCAGGAGGCCCGAAACTGTGCTG | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
4 | 5_tfbs | I need to know if MAX is likely to bind to this DNA fragment: CTAACCCCTACTGTGCCCAATGTGGTTGTATTTGGAGATGGGGCCTTAGAGGAAATAACAAGGCTAAATGAGGTCACAAGGGTGGGGCCCTAATCTGCTA | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MAX", "true_labels": ["JUN", "SRF"]} |
5 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? AACAGTTACTTTCCATCCCATTTTTGAGCAGATTGACACCTCCACAGGAGGACCTAATCTTGATGTACTGTCTCCTGAAGTCCACTCCCCATATCTGTCC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
6 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GGTATATACCCAGCTTCATTGGCTGCAGCCAGCTCTTACCTATAAGCACCATCTACTGGCCTGTAGGTTGAACTGCACAGCCCAATATTAAAGCTGCCAA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
7 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the TEAD4 transcription factor? CAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTATGATGGTGGGCGCCTGTAATCCTAGCTACTCAGGAGGCTGAGGCAGGA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["MEF2A", "YY1"]} |
8 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CCTGTTGGAGGACAAAATCCTCAACATTAAACTCAGCTCTGGGCGGGACCATGGAATCCCAGTGTTAATGAGTTGTTCAGCAAGAGTAGAACTAGTCAGG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
9 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CTCGCTCAACCTGTCTGCGGAGGGCGCGCTCTCGCGCACCCTGCTCCCGCGTTCGCTTCTTTGTTCCCGCCCACGCGAGGCCCATTTTGACGGATCCAGT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
10 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the MEF2A binding profile? TCCCGACCGCCACAGCCTCCTCCGCGCCCCACACCAGGTGCTCGCGCTGTGTCTCCATCCTCCCCGCAGGAGGACCTTTAAATAGCAACGTCAGCGCGCT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "MEF2A", "true_labels": ["MEF2A", "SP1"]} |
11 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CAGTACCTGATCCAAGCTGAAGAGCACTTGGCCCCAGATCAGTGGACGGAAACGGGCCCCCTCGCCATCTTCTGCGTCAATCTCTCCATTGTCCCCCCCC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
12 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCGCGCAGACCCGGAAGCCACTTACAGTAACTTCCGGCGAGGGTTGGACGACCGCGGAGAAGTGGTCCGGAGTGGGCGGCGTTAGGGCGGTGCTTTCTGG | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
13 | 5_tfbs | I need to know if MEF2A is likely to bind to this DNA fragment: TTTTCTCCGCCCGCGGCCCGAACCCGTTGTGCGGTAGAGGCAGCCGGGTCCCTTTAAGGCCCAGCTGCGCTCCGTCCTCCATTACTCCTTTTCTCCGCCC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MEF2A", "true_labels": ["EGR1"]} |
14 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ATGGCGACTGGAGCCACCTCTCACCGCTCAGGGAGCCGGGAGGGCCGGCAGCTCCCGCGGGCCGAGTTTCCCGCCTTGGGTGCGAGGACGCGTGGGGCCG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
15 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? TGGAGTGCAGTGGCGCCATCTCAGCTCACTGCAACCTCTGCCTCCGGGTTCAAGCAATTCTCCCGCCTCAGCCTCCCACGTACATGGGATTACAGGCACC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
16 | 5_tfbs | Hypothesis: The transcription factor STAT1 binds to the following Human DNA sequence. Is this true? CCCGCCTCTTCTTCTTTTCCCCACGTTCCTGGCAACATGGCCGCCCCTACATACACCCATGTGTGTAGAACATCATGGCGCCTGTATTTGCATATTAAAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "STAT1", "true_labels": ["STAT1", "MAX", "POU5F1", "YY1"]} |
17 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CACTTCGCTCTGACTCGCTGGGCCCCCCCGCCCCGCTCTTACGGGGCCGGCGCATCGGCGGCTTCGCGCCGCCCCGCTCCCGCGGCTGGCCACAGCGCGG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
18 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CAACCTGTCAAAGCTTGTGCGCCACCGCCACCTCCTGGGCACATCTTGTTTCTTAATCAGCCACGAAATCACGTGAACACTTCACATGTGGTTTTGTTTT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
19 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: TGCAGCACCCCAGGGAGGCTCACACAGTGCCCTGCCCTCCTATCTCCATGTCCGCCTACAGGGTAGAGCCGGTGGTGCAGGCCCAGGATCGGGACACAGG. Is this a REST binding site? | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "REST", "true_labels": ["REST"]} |
20 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CAAGCTGCCAATTACAACAGTGACATACACATGTAGTTTGTCACTCTTGTGTGTCACTCAATTCTTCAAGGCCCCTAACCTAATGGCAAAAGTAAAAGTC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
21 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GCTGTGCCTCCGCACACAGCTTTGTCTCCACCTGGTGGACACCCCACCTAAGAGGACAGTGGAGGCGGCTGGTTGGTGAACTGGCTCCATGGCAGAGATC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
22 | 5_tfbs | Is the provided Human DNA sequence a target for the EGR1 protein? GCGTGCACTACAACCTCGCCGCCGGCGTCCAGGCTTCTGTGTTCTATAGCGTGGGAGTAGAGAGCAAACGCCGGCGAGGACGTGACGTTGCACAGGCCTA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "EGR1", "true_labels": ["EGR1"]} |
23 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TACTTCCAAGATCTAAAAAGCAGCAAAATTTAGGGAAGCAAGAAGTCAATTGTATTCTGGCCTTCTGCTGCTTTGGAATTTCTGCTCTCTCAGAGAGCTC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
24 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? AGATTCTCAACAGCCACTCAGCTAGAAACTGCTTAAACAGGCTGAGTTCCTGGTGGGGAGGGGCAGCCGCCTACTGTCTAAGCCTTCCAAGAGACTTGG... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
25 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: ATGTGTGTTGTTTCCCGCCATGTGTCTATATGTTCTCATCACTGAGCTCCCACTTATCAGTGAGAACATACAGTGTTTGTTTTTCTGTTCCTGCATTAGT. Is this a ZBTB33 binding site? | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["MAX"]} |
26 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GCGGCAGGAACCTGGAGGGAGGCGGAGGAATATGTCCGAGAGGGAAGTGTCGACTGCGCCGGCGGGAACAGACATGCCTGCGGCCAAGAAGCAGAAGCTG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
27 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? ATGGTGCATTGCAGTTGCGTGTTGTTCAGAAAGGTCCGTGCGGGTCCCCTCAGCCTGGTCCCCTTAGCGCTGACAGCTCTGGTTCTTCTTTGCTCCCCT... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
28 | 5_tfbs | Can you confirm the presence of a YY1 TFBS in this Human DNAsequence? TCATGAGAGCCCAGCACAAGCCCACACCCTCCAGCTCAAAAAAAAAAAAAAAAAAAAAAGATGGCGGGGCAGTGGCTCAGGCCTGTAATCCCAGCACTTT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "YY1", "true_labels": ["YY1"]} |
29 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GCAGGCCTGAAGCTCACAGCCAGCCCATCATTCAGTGAGTTCGAAATCTTCGGACTGGAAGCCTGACCTAGCCCAGACCCTGTGACTTAAGTCCACAGTT | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
30 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? ACCTCTCAGAGCGCATGCTCTTCGGATAGTCGGTCTGTAGCGCCATTTTCGTATGGAAGGGACTGCACTCTGATTAGGTACAGCCTTAGGACGCCCAGC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
31 | 5_tfbs | I need to know if YY1 is likely to bind to this DNA fragment: TAGCCTGAATGTACTGCCAGACTGTGTCCCAACCAGGGGATTTGCACATTATGGTTATCACAAAGGAATGTGGTCTGTTGCCTGAGATAAGCCAACACCC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "YY1", "true_labels": ["TEAD4", "GATA2"]} |
32 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CGGAAGCTGGAGGCCGGGAAAGCTGGGTGGCGGGAGGTCTCAGGCGAGGGAGAGGGCCTGAAAGCAGAGGCAAGGAGTGCCTGCAGGGGCTCCGGGCGGC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
33 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? AAAAAAAAAAAAAATTAATAGATAAAACAGGCCACTAGAGGGTGCAGTTATAAAGAAATTGATGAGGTTTTTACCTTTTTAAAATATTGGTTAGAAGTTC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
34 | 5_tfbs | Is CTCF occupancy expected at this locus based on the Human DNA sequence provided below? CCTCCCCCTGCGCCTCACACGCTCATTGTGAAGCGACAGCGGCCGCCGGCTTCTAAGGCGGTTTGAGACCTTAAGACCCTAAATCCTTGGCGCGCGTGAG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "CTCF", "true_labels": ["NRF1"]} |
35 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CATTAGCCAACCTCTCTTTATCTCCTGCCCCCACCCACACATAGCCTCTGTTATCTTTCTACTCTCTATCTCCATGAACTTTTTTAGCTCTCCCGTATGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
36 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GCGCGATCTAGGAAAGACTCTTAAGCCAATAGAGGGCGCCAAAGGACCTTTAAAAGCCCTTTCAGCACTGAAGTGAGGGGAGAGCGCTCTGGTTGTTCTT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
37 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the SP1 transcription factor? CCGGGGCCGGAAGCAGTGGGCGTACCCGCCGGCTGTAGCCGTAAGACGCATGCGCTAGGCCGGGCCAACGGAGCCCGCCTTTACCTCCCCACTCGGCGTC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "SP1", "true_labels": ["SP1", "EGR1"]} |
38 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TTTCACCTATTGTATTTTCTGAGCTTAACAGAATAGGTTTCTTTTGTAGTCTAAAAAGAGCTAAACTTTTCACAACATTTTGAAGGGACCTACTCTTGTG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
39 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? TCTCCTTGGCTCAGCTCGGCCCTCAGCCCCCTTTAGCCATAAGATGGCGGCCCGGCTCACAGCAGTGACCCCGGGCGTCCTGTCTCCTCCCTGCGCAGTG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
40 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the REST transcription factor? TCCCTAGCTACAGACATCCTGTGGGCTTCCTGTTTCTACTGAATCCAGGGCACATCCCCCAGCCTAGGATTCACAATCTCTACTGGGGACAGGGGCATTG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "REST", "true_labels": ["REST", "GABPA"]} |
41 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GCTACGCGGAGGGTTCCCAGGGCCAGAACGCGAGGGGCCGACGTCTGGCAGTGCCGTTCGCGAGCAGCTTGTCTGCTGCCTTACGGGTGCGGCTGCGCCA | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
42 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CAATGGAGTCCTGGTACTTCTTCCCGGCCATGACGGAGATATAACCAGAGAAGCTCACTTGATCCTTGGGTGTGCCGAGTTTCCCCTGGTGTTTAATCA... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
43 | 5_tfbs | Can you confirm the presence of a REST TFBS in this Human DNAsequence? ACCCCCATGCCTGCCTGCGAGGGCCTTTCTGGGCTGCTGTCCAGAGCGCATGCGCCGCCCTGCTGCGACCTCTCCGCAAGGGCTGCAGGGTGGGCCAGGT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "REST", "true_labels": ["REST", "NRF1"]} |
44 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GGTAGCACCTGGAAGTCAGGGATCATTGCTGACTTATCTTGCCTCCCAACATTGATCATGCAGTAGGTGTGGATGAGAAAGAGGGAGATAAGGGAAGAAA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
45 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GTTCAGGGACAGGGCGCAACCGGAAGCGGCTCCGGCTCCCGGCAGGCAACGCGAGGAGGCGGAGGTCTGGTGGCCGCTCGGCGGCCCCACCTGTCACCT... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
46 | 5_tfbs | Could you verify if the motif for E2F1 is present in this specific Human DNA sequence? AGGAGAATTACTTGAGCCCGGGAGGCGGAGTCTGCAGTGAGCCAAGATGGCGCCACTGCTCCAGCCTGGGTGACAAGAGCAAGACTCCATCTCAAAAAAT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "E2F1", "true_labels": ["E2F1", "YY1"]} |
47 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CCACTCTGGCAAGGCCCCTCACTCTCACCAAAGCTCTCAGGCCTCTCTCACCTCATCTCTTGCTACCTCCCGCGTGGGCGTCACACCTGACTGCCCTCAG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
48 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CAACCCTGCTCCCCCGCATGCACATGCTTGTGTGCGCACACACATGCATACACACACACACACACACACACAGAGGTCTTATCTGTGATAAACATTTTC... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
49 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the E2F1 transcription factor? TGACTGGGTTTCTTGCGGGGGTCCGCCTTCAGTGAAGACCCTGTGGCCAACCATCTGGGTTCTCTGAGGGTTTTGGCGCCTTCCTTGTCTCTCCTTTCTA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "E2F1", "true_labels": ["E2F1"]} |
50 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? AGCGGCCCGGGGCCTCGCGCCCGTTCCTCCGGCGGCCCCCCCGCGGCCGGGCTTCCCGCGTGCAGAAAGTGGCGGACCCTCGGCGTGCCGGGGTGCGCCG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
51 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CAGCGTGTGGGATGCCAGGCTGGATGTGCTGGGCCTGACCAGCCGCCCGCTTTCCTCTTCTCTTGCCTCTGCCTGCCCCCTGGTGGACAGCTGGGGTAAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
52 | 5_tfbs | Could you verify if the motif for FOXA1 is present in this specific Human DNA sequence? CCGTACAAAATCTGGCCTTAACATTACTTCTCACTATTTTCAGTTCTATACAGTACAATGTAAACAGTTGTTTCCCCTTTTTTTGTTAAGAAGTCTGCCC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "FOXA1", "true_labels": ["FOXA1", "MEF2A"]} |
53 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GGTGGGCGGAGCCTCTGCGGCCAGATGGGTGGGGATTCAACATCCTCTTTCCGCCCCACCTCCACCCGCTCCACCTTCCCCCGCGCTTCCTAGGCGGGAG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
54 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CCGGCCCCTCTCCAGGCCAGCTGAGGCCCTTAGACAAGCACTTTGCTGCCTCCTTGTGGCTTCTGCAGGAAAGGCTTCTCCTCTCTTCCAGAGAGTGAGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
55 | 5_tfbs | I need to know if ZBTB33 is likely to bind to this DNA fragment: AGAGAATGAGGAAGAAGCAAAAGCGAAACCCCTGATAAACCCATCAGCTCTCATGAGACTTACTCACTATCACGAGAACAGCATAGGAAAGACAGGCTCT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "ZBTB33", "true_labels": ["ZBTB33"]} |
56 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? ACCACTCTAGATTGTTACAATAACTAGATAGAGCGAGGGGCTGTCTGCAGTGTAGTACCCTCTTAAGACAGCCCAAAGACTTGCATCTCATTTGTCATCC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
57 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? TTGACTCCGCCCCCGGCTGTGCGCTCATCCCTCGGCTCCGCCCCCGGCTGTGCGTCCGTCCCTCGGTTCCGCCCCCGGCTGCGCGTCTGTCCCTCGACTC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
58 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the TEAD4 transcription factor? CGGGGCGGCGGTAGATGGGACTCGCGGGCGGGCAGTAGGCTAGGCCGGGGATGGGCAGCGCCGGGCGTCCGTCCTGCCGGGCCGCCCGGCCCTTCCCCGC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["SP1"]} |
59 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GCCTTGAGGAAACCAATGTGCATTCCCTCGACAAGGGATAGGTAGTTTGGCACGGCGGCCATCGGTGTGCCTAAGGGGGTTATTGGTGATGCGGTTCGTT | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
60 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CCATGAGAGCTTGTAGTACAAGATTGGGAGAGCGGAAGTGCTGCAGCAGCCATTTATTTCGTGGCTCACACATGGTGTCATTTACCTGCTGACTCACGT... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
61 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for GABPA?
Sequence: TTGCTCCCGCCGCCGTCACCGCCACAGGCACAGACTCTGCCACAGCCGCCGCCGCCGCTGCCGCCGCCCGGTCGCCGAAGCAGCAATACCTCCTGGCTTC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["EGR1"]} |
62 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CGCCGGCCCAGACGTCGGGAGGGGCTCCCAGCCTCACGCCTGGGGGGGGGGCCCTCCACAGGCGAGCCCGTCTCCTCGAGCTGCCCCCACCTCTCGCGCG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
63 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CGGAGACCCAGGCCCCCCTCACAGGCGAGGGGCTGGCACGCGGCCTCTGGAGGAACTTCTGGCCTTCACCGTCTCCGCCTGGTCACTCGTCAATGGCCG... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
64 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the GATA2 binding profile? ATTGTCTTTGTAATTATTGCCTTTCTAGGCAGTGTGAAGTGGTGTCTCACTGTGGTTTTGATATGCATTTCCCTAATGACTAACAATGTTGTGTATCTTT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "GATA2", "true_labels": ["SRF"]} |
65 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GGCTGGCTCATGTTCTCTTTCCATCACTTTCCTTCCCCTCCAAGGGCAGGACTTATACTTTCCCAGCTGTGTTGCCATAAGAACTTCCCAACATGGCTTT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
66 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? AAATTCCAAGCGGTTGTGGGACCCACGCCTCACCCGGAACTTTAAGCCCTGCCGTCTCGCCTGGCGCCCAAACTCTGCGGACCTCCACTGGCCGCCCGCC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
67 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for CTCF?
Sequence: AGAGTTTTCTAGCCTGTGGGGGCAGAAATGATGGCTTTGTTATGCGAGGTATGCAGCACATGAGGAAATAGGTTTTGCTGAGAAAATGTTGAGGTTTGAA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "CTCF", "true_labels": ["JUN"]} |
68 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? TCTAGGACTAGCATGGCGAGGGAAGCCTATTTAGAGCCATATGAATAAGCAGTGCAATATCTTTCAAGGGGCAACCAGACCAAGCCAGTGGCACATGGGC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
69 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TACGGTTCTGGAGGGCAGGGACAGGGGCCCTTCCTGTGTGCCTTGTGGTGCTGAGTGCCAGGCTGGGTGAGCTCACCAAGCCCTCCCTGGGAAGGTGCTG | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
70 | 5_tfbs | Is CTCF occupancy expected at this locus based on the Human DNA sequence provided below? CTCCTGTAGGTGCAGCAGCCCTGGGGCATGCTCACCTCACCTCACCTCAGCTTTGTAAACCAGGGCCATGGGAGACCCCCTCCCTCTGATGCCCTCTCCC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "CTCF", "true_labels": ["CTCF", "NRF1"]} |
71 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGCGTCCCATGATGGTCGATGACTCCTGGCAGCCTTAGTGGACTTTTGAAAGTTCGATTGGCAGGGTTTGGAAAGTGGTCAAGGAGAAAGGAGCACCTTT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
72 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CTGCGCCCCTTCGCCCTGCATTCCGGCCTCTTCCTTTAGCCTCGGCGCGGCTTGCGTTCCGCGTGTACCAAGGGAAGTGGCGGCCGACCTGAGCGCGCTT | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
73 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for ZBTB33?
Sequence: AAAGAGCAAACCACAGCTATTCTCACTTCCCAGAACCCTTTGCTGATTACAGCGTGAGATCAAATCCCCATGGACAGGGCGGACTGGTATTTCAAACATG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["STAT1"]} |
74 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GCACATCTCATATTCCAGGCATAGGGAAGAGCAGAATCTGGATCAAAGAAAATAAATAATAAAACTTTTTAAACCATAAATTAAGAGTTGTGCTAGCCTC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
75 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TCCTCCTCCCACCTTTTGCGCGTCTCGCCCGGGCATCGAAGGAAGGGAATGACGGCGCGACGGCGACCCCTAGGGGCGGGAGGAGGCGCTAGGAGCGGGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
76 | 5_tfbs | Is MEF2A occupancy expected at this locus based on the Human DNA sequence provided below? TGGCTAACACGGCGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTAGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "MEF2A", "true_labels": ["MEF2A"]} |
77 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TCTTTGCTCTAGAACTTTCCTGTTACAGCCACGACTCCCCGTCGCAGCTCGCGAGGGCTGGGCTCTGGTGGGGTGGCCCTGAGACTCATTGGCACCAATA | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
78 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? TCATGGTGGTGGTGGAGATTATTGTTGAAGGACCCTCGCCACCTCCACGCGGCCCGCCGCCCCTTCCCTGAATGGCGGCAAATGCAGTCAGGCGAGCAGC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
79 | 5_tfbs | Hypothesis: The transcription factor SRF binds to the following Human DNA sequence. Is this true? TGGAAGCGAAACTGCGGCCGCGTTGCCTGCTGGGAAATGTAGTTCAGCGGTGGCCTAGCCCTTCAGGCCTGGCCGCTACAATAAGGCTGGCGAACTCGCA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "SRF", "true_labels": ["STAT1"]} |
80 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GGCAAAAAGCCTTTCAGACTCTGAGAAAATATTTTTAAGAGAAGCCTCTCCAGGTGGAGAATTAATTGTTTCTGGTTTATCATTCCAACAAGTTAAATCT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
81 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCCAGAGCAGCCTACAGTCCCGTCTCCGCCGGCTAACCAGACATGACCACAAGGGGGCACCAAAGAGTTTTCATTACTTCCGCAGGTCTTGCTTTGCCTG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
82 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for JUN?
Sequence: TGTTGGATTCTAGTTGAGCACGCTGATGACTCATCAGTTCAAATATCACGTGGCTTTCCTATTTCCCGTGTCAGTTGCAGGGCCTCTAAAATGGCTGTGA | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "JUN", "true_labels": ["RELA", "YY1"]} |
83 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TCTCATTTCCCTTGCAACACAGGCCTATCTGGGCTGGCATTTGCATGGGAAGGCCCCCATGCAGTATTGTTTGGGCGCTCCTGTGTAACCCCTTTCAGGT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
84 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TTGCACTGCGCAGGCGCGGGCGGGGCGCGGGCGCGCGCGCGAGCGAGCGAGGGATTCCCTCTGACGTCATTGCTAGGATACCAAACAAACACTCCGCCGC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
85 | 5_tfbs | Can you confirm the presence of a SP1 TFBS in this Human DNAsequence? GACTATCCCACGCGATCAGCCAGTCGCAGCGCAGAGCAATGAGCTTGACACCTCCTTCCTCCAATCGCAGGGCAGCTCCTCCCAGCCAATGACAGGCCTC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "SP1", "true_labels": ["SP1"]} |
86 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CGGACGCGAACCTCAGCGCCCCGCATGCGAGAGAACGAACTGGGGCCGGCCCAGCGAACGCGCGTTGCGCGGCGTGAGCACGGGGCGCGGGGGCCGGGCG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
87 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TTGCGTTGCTGCTCGGCCTCGCCACTCGTCAGCAGGCAGCCGGGGAAGCACACGGACAGCACGGACCGCGACGGCAGGAAGTCCGCCATCTTGCCGCCGC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
88 | 5_tfbs | Could you verify if the motif for SRF is present in this specific Human DNA sequence? AGCAGGCGCCCGATGATCGAGTCCAGGTTGAGCTTCTCGCTGTCGGACATGGCGGCGCCGCCGCTCCAGCCCAGCAGCTCCTGGCCCGCTCCTGCCTCCC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "SRF", "true_labels": ["NRF1", "YY1"]} |
89 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GCTAATCCCAGGACTTCAAAATCACAGCCCCCTAAAAGTAATCTGGATGGCATAGAGAAGTGTTGCTCAAACAACCATTCTGAACTCCTTTCTTTGCTAA | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
90 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GGAGGAAGGCGGGAGAGCGCTACCGCTGCTACCAAGGCGGCGGCGCGGGCGCTCGGCCGGGACCCTTCCCTGCGTCGCCACCAGATGGCGCGCTCGGCCC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
91 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: CAAAAACCGGAAGCTGTCCAGAAGATGCTGGATCAGGCTGAAAATGAGTTGGAAAATGGCGCCACATGGCAAAACCCGGAACCCCCCCTTGGATTTCAGA. Is this a E2F1 binding site? | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "E2F1", "true_labels": ["E2F1", "YY1"]} |
92 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CCTGAACCGCCAGCCCATCAGCTGTGTGGGACTGGCTGAGTCAGGAACTTTTGGCATTCCCGCCCTAGGCTGAGCCAAAGAAGTCTCCCACATGGGAAGC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
93 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CTGGGCAATGGCGGGCGCCCCTCCCCCAGCCTCGCTGCCGCCTTGCAGTTTGATCTCAGACTGCTGTGCTAGCAATCAGCGAGACTCTGTGGGCGTAGG... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
94 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for MAX?
Sequence: TCGCAGCGTGGCGGCCGCAGGAGCTGAGGGAGTCGGCCGCGCTTGCGCGGGGAGTGTCTTTTCGTCTCCGGGCGGCGGCAGCAGCGCGTGTGTCCGGAAC | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "MAX", "true_labels": ["NRF1"]} |
95 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GAAGAGGTAACCTGCCATCAGGTCAAGAGCTTCCTAGTTCCAGCACCGTGGACAGCTCCAGCAACGTCGCTCGAGCTTTCCTAGGAATTCCACCTGAAGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
96 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GCTCTGCCCTCTCCAGGCGCGGCGCTGCTTGCTCTGCCTGAGCTGCCTTCCCGCCCAGTGCATCCCGCTTCTCCCCCGGGAAGACCCAGGAGCGTACGG... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
97 | 5_tfbs | Could you verify if the motif for STAT1 is present in this specific Human DNA sequence? TTCCACAATCATAGAGGCAGAGAACTTGCCAAGCTGTGCGCAGGCTCTGAAAGCTACTTCCTAGAAGTAACAGTCATCACTTCTGCTCAAATTTCACTGA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "STAT1", "true_labels": ["NRF1", "STAT1"]} |
98 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ATCTATTGCCTACTTTCACCATGAACTCCCATTATCCAAGTTTAAGTATTTCCAGCGCTTCAATACAAGGGTAGATTGGCCATTCTAGGAGGTTGGGTCA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
99 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? ACTGCCCCCTTCCGTGGCCGTGGCATGCACACGCTGCCCCCTTCTGTGGCCATGACATGCAAATGCTGTCCCCTTCCGTGGCCATGGCAGGTGTCTCTGA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
100 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: GGCGGCGCCATGTGAGTGCGCGCGGGGCCGCGCTGGGGCCGCGGCGGGAGGTTACCGTATTTACCGAGGCCAGAGCCGGACCCTCGGGGGCGGGTCACTG. Is this a GABPA binding site? | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["SP1", "EGR1"]} |
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