id int64 | subtask string | question string | options list | answer_index int64 | answer_text string | metadata string |
|---|---|---|---|---|---|---|
101 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GATTGCATCACAACAAGATTACTTTACTAGCATTTGACAGGTGAAGGATCTCTCGTTGATAGATTTGTTTTGCTAATGTAACGGGAAGTTCATTGTTGGT | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
102 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CCCCCGCCCTCCCAGCGGCAACTCACCATTTTCCTTCCGGCCGTCAGCGGCCTGTCGCCTACACTCGGGCGCCTTTAAGAATGGCACGGCGGCCGCCTCC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
103 | 5_tfbs | I need to know if NR3C1 is likely to bind to this DNA fragment: TGTGTCCCTGTAATGGCTGACACCGGCGCTGGCTGTCAGGCACATGGCTAAGCACATGGCCTGGGTGACACCATGTACCAAACACACAGCAGTCGGTGGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "NR3C1", "true_labels": ["MAX", "NR3C1"]} |
104 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CCTTGACCCACCAAAAGCATTGACCACAGTGCTTAGGAAATCAGTGATGCATGACTGAGCCACGCCAGTCCTGCAGAGGCTGCCGACACCCGTCAAGTGT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
105 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? AACAAGGGCTCATTTCACTTATTATGATCAATGACTGCCACCTAGTGGATATAACTTTCCTCAAATCTCTATATTGAGATTTCCTAGTGCTTACACTTC... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
106 | 5_tfbs | Hypothesis: The transcription factor GABPA binds to the following Human DNA sequence. Is this true? TCATGCAAAACTATATGTCAGCACCTTAAAAGATTAGCCATAAGATATACAATCATGTCATCTGCAAACAGGGACAATTTGACTTCCTCTTTTCCTAAGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "GABPA", "true_labels": ["GABPA", "POU5F1"]} |
107 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? AGGGAAAGCGGGGAAGCAGCGGCGCGGCAGCAGTTCGGCCTTCGTGCCCCCGGCTCCAAATCCCGAGACTTGAGAGAGTTCAGGCGGGTGGATGCAGCCG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
108 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? ACTCTCGGCGGTCCGGGCCCCTCGCCACTACCGCCGCCGCCGCCGCCGTGAGTCCCGCGGAGCCGCGCGCGCCCCCGGCTGGGCCGAGCCGCTGGCCGA... | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
109 | 5_tfbs | Hypothesis: The transcription factor STAT1 binds to the following Human DNA sequence. Is this true? CCGCAGTCGAGTGGAGAACCGAGTCCCGACCTAAGGTCGAATCATCAGGCGTCCCCGTCACCCAACAACCCACTCAGGCACTTCCGGTAAGAAATCTAGT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "STAT1", "true_labels": ["GABPA", "STAT1"]} |
110 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CTTAAGCCTCATCTTCCCTTCCTCAATCAACATTCCTTTCTCCGCAGGACAAGCCCTGCTGTACGTTTCAAATGCAGATGTGATCTTATCAACCCGGTCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
111 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? ATGTGAAGCATTTTGATGCTGGCGCTTTTGTAATCTTTCCAGGAGTTAGCCACAGGAGGTTTTTCACACAGTAACAAGGCTGCCACCTGGCTGACAGTAG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
112 | 5_tfbs | I need to know if ZBTB33 is likely to bind to this DNA fragment: GATGACAGCTGTGGCCAGCGATGGATGGCTGCCCTGGGCGTGGCATGTGGGAGAGGAGATCAACTCCTCACCTCTGCGCCCACCAGCCTGCTTCACTGTG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["SP1"]} |
113 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GGCTAGTTCATTAAACATGTTTACTCTGGTCCATTGTAGCCTCTACGATAAGGAGTATTTTCTCGCTCTGGTGTGGACAGGGCACGCCTCCCAGAGCAAC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
114 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CTCAAAGTCTTAAGGGGCTCCTTTCCTCTAGGCGGAGCCGAGTCAGGTCACACGTGCTCGGCGCCGGCCGCATTCCCAGCTCTTCGCTCATTCGCGACTA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
115 | 5_tfbs | We identified a peak region in the genome. DNA Sequence: GGATTGCTTAAGCCCAGGAGGTTAAGGCTGCAGTGAGCCATGATCACACCACTGCATTCCAGCCTGGGTGACTGAGCAAGATTCTATCTCAAAAAAAAAA. Is this a TEAD4 binding site? | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "TEAD4", "true_labels": ["TEAD4"]} |
116 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? AGATCTGGTTGCTGAGCTGGCAAGCTGATACTCCAAACAAAGTGTCTAGATCACTGTTGTAGTTCGATAACCAAGAAGGGAAATGCAGTCTCTGCCTCTA | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
117 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GCCGGGCCCCCACGTGACCTACTGCGCGGGCCGCCGCCTCCACCGCGCCCAGGCCCCGCCCCCGTGACGTCTCATCGCCCTCTGCCTGTCCGAGCGTTCG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
118 | 5_tfbs | Hypothesis: The transcription factor TEAD4 binds to the following Human DNA sequence. Is this true? CTCTGTGCTCTGGCAGCCTCAGCGATCACAGGCCTGCAGTGCTGCTTTTGGCCCTGCTTGGAAACCCCCATGTGAGCACCAGCAATTGCAGCTCGGCCTC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "TEAD4", "true_labels": ["RELA"]} |
119 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GTCTGGAGAGATCAGATCGCAGCTTTGGCTTCTGGGGACCACCCCATGAAGAGAGGTGTGGGCTGCACACTCACACATCTCTTGTCAGGCTGCCAGGCAG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
120 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GCCTCCAGCAGCCGCCCCGCCCCTGCGGAGAAGTCCCGGGCTGGCGCCGGCGGCCACAGCGGAGCAGCTGGAGCGATCGAGGCTGCAGCGCGGCCGCCGG | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
121 | 5_tfbs | I need to know if POU5F1 is likely to bind to this DNA fragment: GCACTGAAAAACTTATCTAGAAGGAAAATAACCACTCAGTCTAATCAATGTCACATCCTTAGAAGTATATACAATTAGTACAGAAAGGGGATGCAAAATG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "POU5F1", "true_labels": ["POU5F1", "GATA2"]} |
122 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? TATAGAGGAGAAAGAACAGGGGATCAATGGGAGGGCAGCACATTGCAGGCCAGAAGAGGTCCAGTTGGGGAGAGTTTCAGTGGGTCCCAGATGAGATGTG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
123 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CTACGGCTCCGCCCCCCCCGCCGGTTCCCGCGCCCGCTCCCAGCAGAACAGCGACCGCCGCGCGCTCCCCCACTTCCGCTCACAACATGGCGCCTAAGCG | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
124 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for NRF1?
Sequence: GTGTGTGTGTGTTAATGGAATTAAGAGTGGCAGCACACGCAGGCGCAGTGGGCTCTGATCGCTGGAGGTGGGGGTTCGGAAAGTCCCGTGGGTTTTAGTG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "NRF1", "true_labels": ["RELA", "NRF1"]} |
125 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GCGGCCCAGGAAGGAAATGACCGCCCGCCGCAGCCCCGCCGACTGCCTTTCAGTTCAGTGCTTTCGAAACCACAAGGGCGGGCGGGGCTAGAGGAGGAAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
126 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CTCAGGTGGACAGCAGAGGGCAGCCTCTCACAGCGCTGGCTCTCGGCAGGCTCCTGCGGGGCATCTGGAAGGAGGAAGAGGAAACCTGGCTGGGATGGGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
127 | 5_tfbs | Is the provided Human DNA sequence a target for the RELA protein? AACACCTCGGCCTCCGCCTCCCCTCAGGTAGCAGGCTGCGGGGCGCGGGGCCGGCTGCCCTCCCGCAGCAAACTTTGCTTGCTGCTGAATATTGATGAGA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "RELA", "true_labels": ["SP1"]} |
128 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ATCAGATTGTGGGCTGGCTGAGGTCTAGTTTCTTACAGATGCAGGGACCTTGGCGGGCAGTGGGTGCCTCCTCAAGTCTTGCTGTTCCATTGTCTGTGAA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
129 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CCGCGCAGCCAATCGCTCGCGCCAGCGCCAGTCCACGCCACATCGCCCGGCCAATTGGCGCCCGTACGCGCTTGACGACACAATCTCGCCAAGCTTCGCC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
130 | 5_tfbs | Hypothesis: The transcription factor YY1 binds to the following Human DNA sequence. Is this true? CCAGGGCAAGTTCTCTTATCTGTGCCTGCAGCTTGATTTTTCAGGCTGTTCTTTTCTTTGAAAGAATTCAACCGAGGACCCACCCTAACTGCCTGCCTGA | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "YY1", "true_labels": ["GATA2"]} |
131 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? TGACCTAGAATGCCTCAAGTGTCTGGGAATGCAGCCCAGTACGTTTCAGCCTCATTTTATCCAACCCCTATTCAAGATGGAGTTGCTCTGGTTCAAATGT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
132 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GTGAGTGCGGTAGGGCATACCAGAGGGGGGCGGGCGCGCTTCCTCGGGACTCGCCGGCTCGATCAGGCACGGCCCGGCGCTGGGGACCTAAGCCTGGGGA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
133 | 5_tfbs | Is MEF2A occupancy expected at this locus based on the Human DNA sequence provided below? CAACACTTGTTATTTTCTGCTTTTTTTAGATTGCAGCCATCATAGTGGGTGTGAGGTGACATTTCATTGTGGTTTTGATTTGCATTTCCCTAATGAGGAG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "identity", "target": "MEF2A", "true_labels": ["POU5F1", "MEF2A"]} |
134 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? GGCCGTCTCCACGCCTCTGGGCTCTTGCCCGCGCGCGCCCAACCGGCCTGGTGGCCGGTGTGCGGGGCCAATGCTCCTCCTCCAGGTGCAGAAATTCAAG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
135 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? GTGCAGTTAATGTCTCGCTGGGAGTGAACTCCGTCCTTGAAGTCATCTCCCGCTAGGGGGAGAGTTCCAGAGATGCCTCGTCCATGTCAGGATTCGGCCC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
136 | 5_tfbs | Is NR3C1 occupancy expected at this locus based on the Human DNA sequence provided below? CCTCATCTTCCAGGATCACTGATTAGGAACAGGCTGTTCCCCAAGGCCATTTCCATTTCTATGGCAGGCTTTGAATAGAACTAATACATTTTAGAAATGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "NR3C1", "true_labels": ["NR3C1"]} |
137 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? GAGGTTACCGTATTTACCGAGGCCAGAGCCGGACCCTCGGGGGCGGGTCACTGCGGGCGTGCTACCGTATTTGCCGGGTCCCGCGCAGGTCCTTTCCGGG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
138 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? AGCTGCGCCACCTGGCGGAACGTGTTGGCCAGGCGGGTCAGCTCCGCTTTCTGCACCGGGCGGCTGTAGGTGGGCGTGATGGCATAGATGGTGGGCAGCT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
139 | 5_tfbs | Can you confirm the presence of a GABPA TFBS in this Human DNAsequence? CTTTCTCCCATTATCGTCAGCAGGGAAGTAAGTAATCAAGCTCCCCATCTTAAAACTTCGGTAAAATGAGGTCAGCAAGATGTGTGGTATTGACATGGCA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["JUN"]} |
140 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CTAGATCTTTCCTTCAGCCTGGCACAGGGAGGAAGTGAGGTCGACCCTGCTGCAGCCGCCGGAGAACGGCGCTGCGCGACTTGTTCTTGGAGGCGACGTC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
141 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CCCAGAGCCAGCAAATGCTCCTGGGAACTCAGCCTGGACAGCAGAGGCAGCAACAGGAAGCCAGGCCAGGCACGCCAGAGCTGGCCTGCTGGGGAGGGGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
142 | 5_tfbs | Could you verify if the motif for SRF is present in this specific Human DNA sequence? ATTACTCTATCCTTATCTCCTAGGGAGGTCATAGTCCATAGGAGGCACTAAGTAAATCTTTGTTGAGTGAATTTAAGCTGTGTGTTCAGCAATGGTGAAC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "SRF", "true_labels": ["GATA2"]} |
143 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? AGGGGGGACAGCAGGCATCACCACCGCCCCTTCCACGCCGTCCCGCCTCGATGTACCGGGATTCTGTCAAGTGCCTGAGAACATGTTCAAAAAGCTGCTC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
144 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CCCAGCGCCCCTGCCTGGGGGGGTCGCCTTTCGTCCATTTTGCTCCCCTGGGAGAGAGATCGGATTTTGCTTTCGCTGCCGCGAGCCCGGCGGGGCTGCT | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
145 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the POU5F1 transcription factor? CACTTCCCGGCTTGAGCTGCCTACTTGGCCTTTTAACGCATTTGCGTAGGTGACACCTGGCTTCCACTCTGTGAGCCCTAATCCGCATGTGCCCTCCTAA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "POU5F1", "true_labels": ["MAX", "NRF1"]} |
146 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CACACTCTCGCTGCAAAGAGTTGGGCAAGGCTAGACCCTAATGGCCACACCCAGGTCTTGAAGGACTGAGACTGGCATTCTTGCCCGACATGAGCTGGCA | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
147 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? GGATAGGCCTGGAGCTGCCGCCTCCGCCAGGCGACGGGAAACCCTCGGAAGTGGGTTTCCGCGCGAAAGTAGCATTGCGGCCAGGCGGGAAACGTGTTCG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
148 | 5_tfbs | I need to know if MEF2A is likely to bind to this DNA fragment: CTGAAGTCATTGTGAATGCTCTGGCTCTAAAATATACTGCTAAAAATATATTGTTATGGTGACTCATAGCATTTTCACTGGTGATGTGATTTTCTGAAAT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "MEF2A", "true_labels": ["MEF2A"]} |
149 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? AAGTTTACCCATTAAACCTCGGAAAAGTTGACCAGGTTTTTTGCGTCAAAAATATTTATTTTGCCAAAAATTTTAAGTTTCCAGTAATACCCTCAGACTT | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
150 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? AAGGACCAACTGCGCGTGCGACCGCGACCTCTTTAGCCCGCCCTCCTGTGCCTGCTTCCTATTGGCTGGTAGTAGTTCCCGCCTAGGTGATTGGGCCAA... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
151 | 5_tfbs | Can you confirm the presence of a REST TFBS in this Human DNAsequence? TGCCTGAAGACAAATACAAGGCTAACCAGAATGTTTACAAGGAAGAGCCAGGGAATGACACGTCCACAGAGGTTCAGCTATGTTCAGGGCTGTGTGTGTA | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "REST", "true_labels": ["FOXA1"]} |
152 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GTGTTTTTCCCTTACCAGTCAAGTGTTCCTAGAGGAAGGTCATATACCAGTTAAACTCTACTACTGTGCCTCTTAGTGCGCATGCTTGAGCCCAATCACC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
153 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TTACATCATAGATGGCGCCAATCTCTCCTACCCAGGGTAATGTTTGGTCATTGTCATTTTGGCCTTTCTTTTTCCCCATATCTAGTTATTGCTGAAGCCC | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
154 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the TEAD4 binding profile? CTACTGCAACATTTTGGTATTTGAAATGAAGGGACCTTCCATACTTATGCTGTTAATACTTTCATTCTCACTAGGGATGAAGCACATTCCTAACCTGCTT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "TEAD4", "true_labels": ["TEAD4"]} |
155 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GGCATCAGCCTCGAGACACTGCCCTTCCAGACCAGGACCACCTCGTGAGGATGGCGCTTCAGCTCTCTGAGTAGACAACCAAAAACCTCAGTCAGACTCC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
156 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? TCGCGCTACGGAAAGCCGGAGGGGGGCGGGGCCGTCGGCGTAAGGGGGTGTGTCCGCGCGCACCACGGGGGCGCGCGCCGGCTGCTGACTGGAGGCGGCG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
157 | 5_tfbs | Can you confirm the presence of a MEF2A TFBS in this Human DNAsequence? AGGTCATGAAAGGTGGCAAAGATTGAGGAAATGTCATAAAATGGAGGCCACTAAGGAGGCATGACCACTAGCGGTGACATGAGACCCTCGACTAGATGCT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MEF2A", "true_labels": ["YY1"]} |
158 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? TATCTTGGATTATCTCATTTCATTCTCACAATATATGATGGAATAAGTACTGTTACTGGCTATAAGGGAAATGGCTGCACTTTAGTCAGGAGTAGGCTGA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
159 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CGCCCCCGCCGGAGCCTGCGACGGAGACAGTTGTCACCTCGAGGCCGCCGCCGCCACAGTCAGCTGACAGCCGCCGCGCCCCGCCCCCGGCACCGCCCCA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
160 | 5_tfbs | Is SRF occupancy expected at this locus based on the Human DNA sequence provided below? TTGTACTCCAGCCTTGGTGACAGAGTGAGACCATGTTTCCAAAAAAGGAGAGAGAGAGGCCAGGTGTGGTGACTCATACCTGTAATCCCAGCACTTTGGG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "SRF", "true_labels": ["SRF"]} |
161 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGCTTGAAAGGGCAGTAAGGTAAGAAGAGATGAGATAAGAGCAGATGTAGGCATTTTCCACAGAAGGAAGAAGAGAAATATCAGAGAATGATAAGGAAAC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
162 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? GCCGCTGGCGGCTTGATGTTGTCATCACTGCGCGCCCGTTTCTGTCATAAGCTGTGGGATCCAACCAGAGGGAAGAGATCATGGCCGATCGACTAGCGA... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
163 | 5_tfbs | Is the provided Human DNA sequence a target for the E2F1 protein? CCTCCGCCTCCCACAAACGGTCGTGCTGACGTCACGGACGCCCCGGCCGAGCTGCGGCTAGGGGGTCGGGGGACGTCCCCTCGTTCGCCTCGCTTCCCCT | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "E2F1", "true_labels": ["JUN", "EGR1"]} |
164 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TGAAGTCCAGACGCCTATAAAACAGGGATCTTGCACCGGTACAAGTGGGGACTGGCCTCAACCTGAATCACCCAACATGGAGAGAACTTTGCTCCCTGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
165 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CGCGCGCGGCCTGGCCCCTCCCCTCCGCACGCCGGTCCCGCCCCTTGAGCCCAGTGCGCAGCCTCGGATTGGCCAGGGCGGCTTTCGCTCCTCTGGTGG... | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
166 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the REST binding profile? CATTTTAAGGTCTCGCGGGCTTCGGAGGCCCCTCCCTCACTGAGAAACCGGCTTTTGTCGTTCTTCTGAAGCCAGAGCTAGTCTTTCCAGGTGTTAGTCG | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "REST", "true_labels": ["ZBTB33"]} |
167 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? CCGGGGCCGGGGGCGCGGCGGCGGCGACGGCAAGGATCGCGGCGGCGGTGGACAGCGGCGGGGCGGCGTGGCCAAGAGCAAGAGCCGCCGCAGGAAGGGC | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
168 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CAGTTAGATTTGGAGGTTCAACTTCAACATGGCCGAAGCAAGTAGCGCCAATCTAGGCAGCGGCTGTGAGGAAAAAAGGCATGAGGGGTCGTCTTCGGA... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains E2F1, No CTCF"} |
169 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the FOXA1 transcription factor? CGCGCGGGAGTGGCGCTGTCCTAGGTGCCTCCCAGGCTGCCCAGCGTGCTCAGCTGGCCTGAGCGGGAGAATGCGGCCCGCGCTGCAGCCAATCAGCGTC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "FOXA1", "true_labels": ["REST", "EGR1"]} |
170 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ACCCTCTGCACCCCAGGCAAGACATGCCTACCCACTCGGTCTCCTTCAGAACCACGGACAGTGCCGGCGAGCACCACGCGCCACTGACCTGAGCTTCTAG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
171 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? ACGAAAGACTGCACCATTCTTTAGATGACAAAAACAGACGTTTCTGGGAAATAAGCAAAGGAAGAGCCCCACAAGCAGCGGCCTCTGGTGGCGTGCCGTG | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
172 | 5_tfbs | Hypothesis: The transcription factor EGR1 binds to the following Human DNA sequence. Is this true? CTGAGGCCGCTCTCACGCGCTGGCCCTTTAAGATACCTCCCCTCCTCGCCCAGCCTTCTCTCCTATCCCCGTCAGCGCCCCCACCGACAACTCCCGAATT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "identity", "target": "EGR1", "true_labels": ["SP1", "EGR1"]} |
173 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CCATTCTCAGAAAGGATCAATTTTCTTGCAGAGTACAGGCACTTGCCATATGGGTGCCCATTAATACCAAAAGCATTTCATTCCCAGGTTACATTGGAGC | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
174 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? TTGTCTGACTCATTCCTGGCACTCTTCCTCTTCCCTCTGCTTCAGCAGCTGCTCTCTTTCAAGTCCTCCGATCTGCCAATCACACCCCTGCCTCCTGAGC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
175 | 5_tfbs | Please classify this Human DNA sequence: Does it belong to the RELA binding profile? CTCCATCTTGAAGATGCGGCTGTGCTGCCACACACCTCTGAATTCTAAGCCCTCTCACAAAATGGCTTTCCTAATACTGCATGTGTCACAACCAGATAAG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "RELA", "true_labels": ["GATA2", "YY1"]} |
176 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? GTGTGCCAACTAACACCCCCCTGCTTTTCTCAGGTAAGGGGGTCGGACTCCCTCTCAGTCGGAGCCTTCATCGTGTCTCGAGTCGCCCCTCTGGGTGCCC | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
177 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CCCCTGGAGCTCCCACACAGGGACCCAGCTGGCCTCTCAGAGAGAAGAGGCTCCCTGGAGGCCCAGCAGGAAGTGCAGTTTCCCCTTTGACCTGTCAGCT | [
"No",
"Yes"
] | 0 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
178 | 5_tfbs | I need to know if GABPA is likely to bind to this DNA fragment: ACATGGCATTGGCCAAGTAGAGACCCCATCTGCATAACAAAAGATTAGGGTGGGATGGCCAGCTTCTTCGCACACTATGCAAATGGGACACCTGGTCTGA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "GABPA", "true_labels": ["POU5F1"]} |
179 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? ACGCTCTCCTCCCAAGAGGAACCTCGGCTCTTCCGCGGCAGAAGCTGCACGGAACCAAGAAGCCGCGGGCGCTGGTTCTCCAACGAGCTTTTCTCCCGTT | [
"Yes",
"No"
] | 0 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
180 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CCATGGTCGGGGCTTCCAGGCTGCGCATGGCCGCCTGCGGGGCAGGGTGGCCGGCGCGGGCCCGGGGCGGGGCTCCCGGAGCCGTGTGTTAGGCCCGCGG | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
181 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the POU5F1 transcription factor? CATATTTGAGTGATCATAAAGTTCACCAGCAGAAGGTGATGTTGCCGCACTAGATAAAGAAAAGCCTCTGGTGGCCACAGCAATGACCACTTCTTCTCTA | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "POU5F1", "true_labels": ["CTCF"]} |
182 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CTCGTTCCTCTTTACAAGCCAACCCTCTTTTTGTTAACCCTTTGTTGCTGCACCTGAGAGGAGTTACCTCTCGCTTCTTGGCACCACTGCTCTCGGAAAG | [
"Yes",
"No"
] | 1 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
183 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CACCGCCCCAAAGTGGCTGGAGGAGGCCGAGGAGCGGTTGACGCTGAGGTCCATCCCATTGTAATTGTAGCCGTAAGAGCCGGTGTGCATGGCAGCGGGA | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
184 | 5_tfbs | Is ZBTB33 occupancy expected at this locus based on the Human DNA sequence provided below? TGGCATCTGCTGTGGTGAGGTCAGAATGGAGCATGCTGCCTTGTGTTTGCATGCCAGCAAGGGGGTGACAGACGCGATATTGGGTGGAAGAAAACATGCG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "ZBTB33", "true_labels": ["JUN", "POU5F1"]} |
185 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? CTCCCCCGAGGGCCCCGGAGACCTCTTGTCCTCGCGCCGCGGGAAGGGCCTGGGGAGCTGTCCAGGGCTCGGGGTTTTGGAGGTGCTTGAGCCTCCCTGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
186 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? CTCTGGGCCCGGGCCCCGCCCACTCCGGGCTTCGCCGGAGGCGGAGGCAACGTCGTGCGCACGCGCAGGCCGTGGTGCGGCCCCTTGGAGCGCCGGAAGC | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains NRF1, No CTCF"} |
187 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the MEF2A transcription factor? CAGGGGTCGCGAGATTGGCGGGGGCGCGCGAAACCCGAGGGCGCGAGATTTGAGGGGGCGCGCGAGATCCCCGAGCGGGTCTCGGGGGTCGCGAGGCCTC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MEF2A", "true_labels": ["ZBTB33", "EGR1", "NRF1"]} |
188 | 5_tfbs | Is this a real regulatory DNA sequence or a background sequence? TCTGTCTCCAAAGATCTCCCCACGTAGGCACCAAATGGAAGGACCCCCGCCCAAGGCCTTTGTCTCCAGCTGATAGATTCTGCTCCATTTCTGGCATCAG | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
189 | 5_tfbs | We are looking for a sequence bound by the master regulator of chromatin looping and insulation. Is this sequence a match? CCGCCAAGTGCTGCAATGGCTGCCGGGCCTGGCCCCACCACTCCTCTCAGCTCCGTCGCCGCCATGAGCCGCCGCCGCCTGGAGATACAAGACCGGAACC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
190 | 5_tfbs | Looking at the regulatory code, does this Human DNAsequence recruit the CTCF transcription factor? TAGAGTGAAAATACTGAAAGCTACTTTGGTAATTGTTAGGGACAAGCTACCCCAGGAATCCCCCCAACTTCCCCTTACCCTGAATACTCTGCAGCTGCCT | [
"No",
"Yes"
] | 0 | No | {"dim": "identity", "target": "CTCF", "true_labels": ["RELA"]} |
191 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? TCCTCATGCACTCTTGACCAAGTCTGTTCGCCAGCCTTAAAAAAGGTGTCAACTAGGGACAATGGATGAGCATTGATCCCTTGATGAGGGTTGAAGATGG | [
"No",
"Yes"
] | 0 | No | {"dim": "existence_shuffle", "note": "Shuffled background"} |
192 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? CACGCCAGGGCCAGGCGGAGGCGGGGAGCCAAGCCCGCAGCCACGCCCTGCCCAGGGCGCAGGTGGGCTCGGCTGGAGGAGGTGCTGGGGGTGGGTGTG... | [
"Yes",
"No"
] | 0 | Yes | {"dim": "3d_structure_ctcf", "note": "Contains CTCF"} |
193 | 5_tfbs | Is REST occupancy expected at this locus based on the Human DNA sequence provided below? ACCTGGATTCCAACCCTGACCTTTGTACAGCTGACTAGTTAGGGGTTCATACCCATTCTAATGCAAACACATGAAAACAATTAAACAGCCAAATTCCAGG | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "REST", "true_labels": ["TEAD4", "POU5F1"]} |
194 | 5_tfbs | Can you distinguish if this is a biological TFBS-containing sequence (Yes) or a random synthetic sequence (No)? GCCCGCCGCGGCCAGGTCGGGCGGTGCCGCGCAGGCCGCCTCCCCCCCTCGCTTCCCAGTCGGCTTACGCATCCCCGGCGGCGGCGGCGCCGGCATCGGC | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
195 | 5_tfbs | This protein is a key regulator of chromatin architecture, organizing the genome into topologically associating domains (TADs). Does the following Human DNA sequence contain a binding site for this architectural protein? AAGAAAGACATAAACACGCACAGGAAAGGGCTTTTGGAGACAGTGCTGGGGAGCCCCAGTGACCAGGCCGGAAACACTGTAGGAGGTGGGAGGGAGATA... | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains GABPA, No CTCF"} |
196 | 5_tfbs | I am analyzing a Human DNA sequence from a ChIP-seq experiment. Does this sequence contain a binding site for REST?
Sequence: GTGCGTGCCTGTAATCCCAGCTACTCAGGATGCTGAGGCAGAAGAATCGCTTGAACGTGGGAGGCAGAGGTTGCAGCAAGCTGAGGTCACGCCACTGCAC | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "REST", "true_labels": ["JUN"]} |
197 | 5_tfbs | Does this sequence look like a genuine Human DNA sequence containing a Transcription Factor Binding Site (TFBS)? CAGTTGTGGAAACTGAGGCTCAGAGGGTCAGGGGCCTGCTTAGGCTCCCCCAGCCCGGACAGGGCCCAGCAGAACCGATTTCTGCCGGAATGGCCAGGAA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
198 | 5_tfbs | Does this Human DNA sequence bind the 11-zinc finger protein responsible for establishing chromatin boundaries? AAGTGCGGGTGTGGGGCGCGGCCGGGGCGGAGACTTCGGGCCCGGCTGGCGGGCGGCGCCGGGAGCGCGGGGGCGGCGGGCCCGGGTCGAGCATGTAGCG | [
"Yes",
"No"
] | 1 | No | {"dim": "3d_structure_ctcf", "note": "Contains SP1, No CTCF"} |
199 | 5_tfbs | Hypothesis: The transcription factor MEF2A binds to the following Human DNA sequence. Is this true? TTGCAACATTGGTTTAATTATCATACCCCACCTTCCACCCCCGTTCTCTGACCTGCTCCTGCCCTCTTCCTCCTGCCTCATTGAATAGTGGGGCTTTCCA | [
"Yes",
"No"
] | 1 | No | {"dim": "identity", "target": "MEF2A", "true_labels": ["RELA"]} |
200 | 5_tfbs | Analyze the nucleotide composition. Does this DNA sequence likely contain a functional TFBS? CGCTGACACTGCGACTGCCCCCAGCGCATTTTGGGGATGACCTCATGGATGGTAAAAGCGCCCAGCGGATTATAAGGGCCAACAAATGGGGCCTTTACTA | [
"No",
"Yes"
] | 1 | Yes | {"dim": "existence_shuffle", "note": "Real TFBS sequence"} |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.