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12,300 | External Cardioversion of Atrial Fibrillation Causes an Early Improvement of Cardiac Performance: A Longitudinal Strain Analysis Study. | Atrial fibrillation (AF) is often associated with heart failure. Several studies have demonstrated that resumption of sinus rhythm (SR) improves cardiac output in the long-term. Aims of this study were to evaluate the acute variations of left ventricular (LV) performance, following successful external cardioversion (EC... |
12,301 | Alternans and Spiral Breakup in an Excitable Reaction-Diffusion System: A Simulation Study. | The determination of the mechanisms of spiral breakup in excitable media is still an open problem for researchers. In the context of cardiac electrophysiological activities, spiral breakup exhibits complex spatiotemporal pattern known as ventricular fibrillation. The latter is the major cause of sudden cardiac deaths a... |
12,302 | A study of ECG pattern, cardiac structural abnormalities and familial tendency in patients with early repolarisation syndrome in South India. | Early repolarisation (ER) on ECG, which was initially believed to be benign, has of late been considered otherwise. Brugada syndrome has recently been thought to be an extension of the ER spectrum, and the familial tendency of the ER pattern is being highlighted. With attention being drawn to ER's association with idio... |
12,303 | Arterial stiffness determined according to the cardio-ankle vascular index is associated with paroxysmal atrial fibrillation: a cross-sectional study. | Several lines of evidence suggest that atrial fibrillation (AF) may be a consequence of vascular disease. We investigated the relationship between cardio-ankle vascular index (CAVI), a new index of arterial stiffness, and the presence of paroxysmal AF (PAF).</AbstractText>181 outpatients (91 patients with PAF and 90 ag... |
12,304 | Atrial fibrillation in ventricular-paced rhythm: under-recognised, underdiagnosed and potentially dangerous. | There is only scant published evidence demonstrating the importance of diagnosing atrial fibrillation (AF) in patients with a ventricularly paced rhythm. This potential pitfall to recognise AF has the implication of devastating outcomes.</AbstractText>A short survey was undertaken in order to gauge the ability of docto... |
12,305 | Predicting Survival with Good Neurological Outcome Within 24 Hours Following Out of Hospital Cardiac Arrest:The Application and Validation of a Novel Clinical Score. | Despite 50 years of research, prognostication post cardiac arrest traditionally occurs at 72 hours. We tested the accuracy of a novel bedside score within 24 hours of hospital admission, in predicting neurologically intact survival.</AbstractText>We studied 192 adults following non-traumatic out-of-hospital cardiac arr... |
12,306 | [Obesity and the prognosis of heart failure: the obesity paradox, myth or reality?]. | Obesity has now reached epidemic proportions worldwide. Obesity is associated with numerous comorbidities, including hypertension, lipid disorders and type II diabetes, and is also a major cause of cardiovascular disease, coronary disease, heart failure, atrial fibrillation, and sudden death. Obesity is the main cause ... |
12,307 | Echocardiographic predictors of ventricular tachycardia. | Patients with structural heart disease are prone to ventricular tachycardia (VT) and ventricular fibrillation (VF), which account for the majority of sudden cardiac deaths (SCDs). We sought to examine echocardiographic parameters that can predict VT as documented by implantable cardioverter-defibrillator (ICD) appropri... |
12,308 | Psoriasis is associated with subsequent atrial fibrillation in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention For Endpoint study. | Inflammation contributes to the pathogenesis of psoriasis as well as atrial fibrillation. The impact of psoriasis and its association with new-onset atrial fibrillation was assessed in hypertensive patients with left ventricular hypertrophy (LVH).</AbstractText>The predictive value of baseline or incident psoriasis for... |
12,309 | Hypokalemia promotes late phase 3 early afterdepolarization and recurrent ventricular fibrillation during isoproterenol infusion in Langendorff perfused rabbit ventricles. | Hypokalemia and sympathetic activation are commonly associated with electrical storm (ES) in normal and diseased hearts. The mechanisms remain unclear.</AbstractText>The purpose of this study was to test the hypothesis that late phase 3 early afterdepolarization (EAD) induced by IKATP activation underlies the mechanism... |
12,310 | Mechanisms underlying the development of the electrocardiographic and arrhythmic manifestations of early repolarization syndrome. | Early repolarization pattern in the ECG has been associated with increased risk for ventricular tachycardia/fibrillation (VT/VF), particularly when manifest in inferior leads. This study examines the mechanisms underlying VT/VF in early repolarization syndrome (ERS). Transmembrane action potentials (APs) were simultane... |
12,311 | Retrograde flush is more protective than heparin in the uncontrolled donation after circulatory death lung donor. | Formation of microthrombi after circulatory arrest is a concern for the development of reperfusion injury in lung recipients from donation after circulatory death (DCD) donors. In this isolated lung reperfusion study, we compared the effect of postmortem heparinization with preharvest retrograde pulmonary flush or both... |
12,312 | Advances in modeling ventricular arrhythmias: from mechanisms to the clinic. | Modern cardiovascular research has increasingly recognized that heart models and simulation can help interpret an array of experimental data and dissect important mechanisms and interrelationships, with developments rooted in the iterative interaction between modeling and experimentation. This article reviews the progr... |
12,313 | Long-term follow-up after atrial fibrillation ablation in patients with impaired left ventricular systolic function: the importance of rhythm and rate control. | Atrial fibrillation (AF) ablation is increasingly used in patients with reduced left ventricular ejection fraction (LVEF), but long-term outcomes are still unknown.</AbstractText>To assess the long-term effects of AF ablation in patients with systolic heart failure according to rhythm outcome.</AbstractText>We included... |
12,314 | Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis. | The two-pore domain potassium channel, K2P3.1 (TASK-1) modulates background conductance in isolated human atrial cardiomyocytes and has been proposed as a potential drug target for atrial fibrillation (AF). TASK-1 knockout mice have a predominantly ventricular phenotype however, and effects of TASK-1 inactivation on at... |
12,315 | [Analysis of risk factors for all cause-mortality in Chinese emergency atrial fibrillation patients]. | To explore the independent risk factors associated with one-year mortality in patients with atrial fibrillation (AF).</AbstractText>This study consecutively enrolled AF patients presenting to an emergency department at 20 Chinese hospitals from November 2008 to October 2011. Their baseline data and therapies were recor... |
12,316 | Left atrial remodeling and recurrence of congestive heart failure in patients initially diagnosed with heart failure. | Left atrial volumes (LAVs) have been suggested to represent long-term exposure to elevated pressures. This study examined the recurrence of heart failure (HF) based on LAV in patients initially diagnosed with congestive HF (CHF).</AbstractText>This study comprised 77 patients (age, 75 ± 8 years) wit... |
12,317 | RV-only pacing can produce a Q wave in lead 1 and an R wave in V1: implications for biventricular pacing. | Biventricular (bi-v) pacing improves congestive heart failure and mortality in patients with left ventricular (LV) dysfunction and electrical dyssynchrony. Effective resynchronization must include an LV pacing contribution to the QRS. Leads 1 and V1 are often exclusively used to verify proper biventricular pacing.</Abs... |
12,318 | Cardiac Events Theoretically Cannot Be Produced By Non-Ischemic And/Or Iso-Ischemic Myocardium: Challenging Postulations And Vitality Of The Concept Of "Ischemia-Dependent Conflictogenic Arrhythmias". | Ischemia plays a key role in cardiac arrhythmogenesis, particularly in elderly patients. Healthy, non-ischemic and structurally normal myocardium is universally free from dysrhythmias. Thereby intact coronary blood flow prevents potential cardiac events. Hypothetically, ischemia-related electrophysiological differences... |
12,319 | Presence of A Left Atrial Appendage Thrombus After Successful Surgical Closure of the Left Atrial Appendage: A Case Report. | A 64-year-old African American woman presented for defibrillator threshold testing (DFTs) after a recent hospitalization for ventricular fibrillation terminated by her ICD. She had a known history of non-ischemic cardiomyopathy, atrial fibrillation, rheumatic mitral valve disease s/p mitral valve replacement and a redo... |
12,320 | Ablation of idiopathic ventricular fibrillation triggered by ventricular premature beat originating from myocardium of right ventricle: Case report. | We report a case of a 55-year-old woman with idiopathic ventricular fibrillation (VF) who suffered from recurrent implantable cardioverter-defibrillator shocks triggered by short coupled ventricular premature beat (VPB). This VPB was mapped and ablated from the myocardium of right ventricle close to the lateral tricusp... |
12,321 | Combination of epinephrine with esmolol attenuates post-resuscitation myocardial dysfunction in a porcine model of cardiac arrest. | Recent experimental and clinical studies have indicated that the β-adrenergic effect of epinephrine significantly increases the severity of post resuscitation myocardial dysfunction. The aim of the study was to investigate whether the short-acting β₁-selective adrenergic blocking agent, esmolol, woul... |
12,322 | Role of ATP-sensitive K+ channels in cardiac arrhythmias. | The sarcolemmal adenosine triphosphate (ATP)-sensitive K(+) (sarcKATP) channel in the heart is a hetero-octamer comprising the pore-forming subunit Kir6.2 and the regulatory subunit sulfonylurea receptor SUR2A. By functional analysis of genetically engineered mice lacking sarcKATP channels, the pathophysiological roles... |
12,323 | Flaccid quadriplegia due to thyrotoxic myopathy. | Acute flaccid paralysis is an important clinical problem in neurological critical care. After implementing life-supporting measures, it is imperative to identify the correct diagnosis to provide timely appropriate care. Thyrotoxicosis is a recognized cause of myopathy, but rarely of quadriplegia. Here, we report a case... |
12,324 | Altered responses to vasopressors of a patient medicated with carvedilol, pilsicainide and enalapril. | A patient scheduled for laparoscopic rectal surgery was medicated with carvedilol, an antagonist of beta 1-, beta 2- and alpha 1-adrenergic receptors, pilsicainide, a class Ic antiarrhythmic drug and enalapril, an angiotensin-converting enzyme inhibitor. Because the patient experienced attacks of atrial fibrillation wi... |
12,325 | Neurologic complications of cardiomyopathies and other myocardial disorders. | Cardiomyopathies have a variety of causes: infectious, genetic, valvular heart disease, coronary artery disease, hypertension, and tachycardias. All can result in myocardial dysfunction and often congestive heart failure. The main interaction between a diagnosis of heart disease and the brain is via embolic stroke. The... |
12,326 | Neurologic complications of valvular heart disease. | Valvular heart disease (VHD) is frequently associated with neurologic complications; cerebral embolism is the most common of these since thrombus formation results from the abnormalities in the valvular surfaces or from the anatomic and physiologic changes associated with valve dysfunction, such as atrial or ventricula... |
12,327 | Intrapericardial delivery of amiodarone rapidly achieves therapeutic levels in the atrium. | Amiodarone is widely used worldwide as an important drug for managing supraventricular arrhythmias, regardless of its association with potentially severe side effects due to systemic toxicity. Amiodarone reduces the incidence of atrial fibrillation after cardiac surgery, but oral therapy requires a presurgery loading p... |
12,328 | Even four minutes of poor quality of CPR compromises outcome in a porcine model of prolonged cardiac arrest. | Untrained bystanders usually delivered suboptimal chest compression to victims who suffered from cardiac arrest in out-of-hospital settings. We therefore investigated the hemodynamics and resuscitation outcome of initial suboptimal quality of chest compressions compared to the optimal ones in a porcine model of cardiac... |
12,329 | Levosimendan: current data, clinical use and future development. | Levosimendan is an inodilator indicated for the short-term treatment of acutely decompensated severe chronic heart failure, and in situations where conventional therapy is not considered adequate. The principal pharmacological effects of levosimendan are (a) increased cardiac contractility by calcium sensitisation of t... |
12,330 | Current concepts for minimally invasive mitral valve repair. | Minimally invasive mitral valve repair is based on several procedural concepts. Recently, three of them have been intensively discussed: aortic occlusion strategy, use of Goretex-Neo-Chordae to repair mitral valve regurgitation and feasibility and efficacy of the minithoracotomy approach in mitral valve treatment of pa... |
12,331 | Functional characterization of a novel frameshift mutation in the C-terminus of the Nav1.5 channel underlying a Brugada syndrome with variable expression in a Spanish family. | We functionally analyzed a frameshift mutation in the SCN5A gene encoding cardiac Na(+) channels (Nav1.5) found in a proband with repeated episodes of ventricular fibrillation who presented bradycardia and paroxysmal atrial fibrillation. Seven relatives also carry the mutation and showed a Brugada syndrome with an inco... |
12,332 | Exploring which patients without return of spontaneous circulation following ventricular fibrillation out-of-hospital cardiac arrest should be transported to hospital? | Currently many emergency medical services (EMS) that provide advanced cardiac life support (ACLS) at scene do not routinely transport out-of-hospital cardiac arrest (OHCA) patients without sustained return of spontaneous circulation (ROSC). This is due to logistical difficulties and historical poor outcomes. However, n... |
12,333 | Outcomes associated with amiodarone and lidocaine in the treatment of in-hospital pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation. | To determine the association between amiodarone and lidocaine and outcomes in children with cardiac arrest with pulseless ventricular tachycardia (pVT) and ventricular fibrillation (VF).</AbstractText>Current AHA guidelines for CPR and emergency cardiovascular care recommend amiodarone for cardiac arrest in children as... |
12,334 | Acute kidney injury after cardiac arrest of ventricular fibrillation and asphyxiation swine model. | The purposes of the study are to investigate the renal function in ventricular fibrillation (VF) and asphyxiation cardiac arrest in a swine model and to estimate the value of novel biomarkers in the acute kidney injury (AKI) after cardiac arrest.</AbstractText>Thirty-two healthy inbred Wu-Zhi-Shan miniature piglets wer... |
12,335 | Predictors of 6-month poor clinical outcomes after transcatheter aortic valve implantation. | Patient selection for transcatheter aortic valve implantation (TAVI) remains a major concern. Indeed, despite promising results, it is still unclear which patients are most and least likely to benefit from this procedure.</AbstractText>To identify predictors of 6-month poor clinical outcomes after TAVI.</AbstractText>P... |
12,336 | Prognostic usefulness of left ventricular hypertrophy by electrocardiography in patients with atrial fibrillation (from the Randomized Evaluation of Long-Term Anticoagulant Therapy Study). | It is unknown whether left ventricular hypertrophy (LVH) diagnosis by electrocardiography improves risk stratification in patients with atrial fibrillation (AF). We investigated the prognostic impact of LVH diagnosis by electrocardiography in a large sample of anticoagulated patients with AF included in the Randomized ... |
12,337 | Prognostic relevance of pulmonary arterial compliance in patients with chronic heart failure. | Reduced pulmonary arterial compliance (Ca) is a marker of poor prognosis in idiopathic pulmonary arterial hypertension. We tested the hypothesis that pulmonary arterial Ca could be a predictor of outcome in patients with chronic heart failure (CHF).</AbstractText>We enrolled 306 patients with CHF due to systolic left v... |
12,338 | The previous use of digoxin does not worsen early outcome of acute coronary syndromes: an analysis of the ARIAM Registry. | The aim of the study was to determine the influence of the previous use of digoxin on the hospital mortality and complications of patients admitted because of acute coronary syndrome (ACS). We analyzed the data of patients included in the ARIAM-Andalucia Registry, which involves 49 hospitals in Andalucia, Spain, from 2... |
12,339 | Cryoballoon pulmonary vein isolation prior to percutaneous atrial septal defect closure: a case report. | We report the case of a 61-year-old female who was admitted to our department with progressive dyspnea and palpitation. Transthoracic echocardiography and transesophageal echocardiography showed a small atrial septal defect (ASD, 8x7 mm). Paroxysmal atrial fibrillation (AF) was detected in Holter monitoring. As repair ... |
12,340 | Use of automated external defibrillators in US federal buildings: implementation of the Federal Occupational Health public access defibrillation program. | Federal Occupational Health (FOH) administers a nationwide public access defibrillation program in US federal buildings. We describe the use of automated external defibrillators (AEDs) in federal buildings and evaluate survival after cardiac arrest.</AbstractText>Using the FOH database, we examined reported events in w... |
12,341 | Custodiol for myocardial protection and preservation: a systematic review. | Custodiol cardioplegia is attractive for minimally invasive cardiac surgery, as a single dose provides a long period of myocardial protection. Despite widespread use in Europe, there is little data confirming its efficacy compared with conventional (blood or crystalloid) cardioplegia. There is similar enthusiasm for it... |
12,342 | Intravenous immunoglobulin in the therapy of adult acute fulminant myocarditis: A retrospective study. | Acute fulminant myocarditis (AFM) is a serious heart disease with limited treatment. This observational retrospective study aimed to investigate whether intravenous immunoglobulin (IVIG) was able to improve left ventricular function and reduce the episodes of arrhythmia in adult patients with AFM. The medical records o... |
12,343 | Implantable cardioverter defibrillator and inappropriate therapy: "black box" examination yielded both human and technical causes. | We report on a 70-year-old male patient who was recipient of GEM III DR 7275 Cardioverter Defibrillator, and who presented with inappropriate shocks. The patient had a documented slow ventricular tachycardia (VT), and the device was programmed to detect VT at rates >100 bpm, fast VT (FVT, via VT) at rates >150 bp... |
12,344 | Survival, predictive factors, and causes of mortality following transcatheter aortic valve implantation. | Transcatheter aortic valve implantation (TAVI) is considered the standard of care for patients with severe symptomatic aortic stenosis unsuitable for surgery. However, short- and long-term mortality after TAVI are still relatively high. The aim of this study was to establish survival, predictive factors, and causes of ... |
12,345 | Improved cardiac and neurologic outcomes with postresuscitation infusion of cannabinoid receptor agonist WIN55, 212-2 depend on hypothermia in a rat model of cardiac arrest. | To investigate the mechanisms of improved myocardial and neurological function and survival following i.v. administration of cannabinoid receptor agonist, WIN55, 212-2 in a rat model of cardiac arrest.</AbstractText>Prospective randomized controlled experimental study.</AbstractText>University-affiliated research insti... |
12,346 | Update on cardiometabolic health effects of ω-3 fatty acids. | The fish fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may promote cardiometabolic health. This review summarizes the results of recent meta-analyses of prospective studies on cardiovascular diseases, diabetes type 2 and markers of atherosclerosis and thrombosis.</AbstractText>The results of re... |
12,347 | Minimally invasive redo mitral valve surgery without aortic crossclamp. | Reoperations of the mitral valve have a higher rate of complications when compared with the first surgery. With the field of video-assisted techniques for the first surgery of mitral valve became routine, reoperation cases began to arouse interest for this less invasive procedures.</AbstractText>To assess the results a... |
12,348 | Aliskiren ameliorates sympathetic nerve sprouting and suppresses the inducibility of ventricular tachyarrhythmia in postinfarcted rat heart. | Aliskiren is an oral renin inhibitor, which inhibits the first rate limiting step in the renin angiotensin aldosterone system. In this study, sympathetic nerve sprouting and the inducibility of ventricular fibrillation after aliskiren treatment in myocardial infarction were investigated.</AbstractText>Male Sprague Dawl... |
12,349 | Polymorphisms of angiotensin-converting enzyme 2 gene confer a risk to lone atrial fibrillation in Chinese male patients. | Growing epidemiologic evidence has indicated that genetics can predispose individuals to the occurrence of lone atrial fibrillation (AF). The angiotensin-converting enzyme 2 (ACE2) gene has been established to be associated with hypertension and left ventricular hypertrophy. The objective of our study was to investigat... |
12,350 | Effects of early amiodarone administration during and immediately after cardiopulmonary resuscitation in a swine model. | Aim of this experimental study was to compare haemodynamic effects and outcome with early administration of amiodarone and adrenaline vs. adrenaline alone in pigs with prolonged ventricular fibrillation (VF).</AbstractText>After 8 min of untreated VF arrest, bolus doses were administered of adrenaline (0.02 ... |
12,351 | The prognostic implications of lack of palpitations in patients hospitalised with atrial fibrillation: observations from a 20-year registry. | It is well recognised that patients differ in the clinical presentation of atrial fibrillation (AF), ranging from the typical symptom of palpitations, atypical symptoms in others and a substantial that are asymptomatic. Whether the different patterns of presentation are associated with differences in outcomes is not kn... |
12,352 | Clinical and therapeutic aspects of amiodarone induced thyroid dysfunction. | Discovered in 1961 by Tondeur and Binon, two Belgian chemists, amiodarone was widely used, especially in Europe, initially as an antianginal agent, and later as an antiarrhythmic one (following the experiments conducted at the University of Oxford by Dr. Bramah Singh). Thus, the role of amiodarone was reconsidered, bec... |
12,353 | The importance of avoiding unnecessary right ventricular pacing in clinical practice. | Symptomatic bradycardia is effectively treated with the implantation of a cardiac pacemaker. Although a highly successful therapy, during recent years there has been a focus on the negative effects associated with long-term pacing of the apex of the right ventricle (RV). It has been shown in both experimental and clini... |
12,354 | Predictive value of atrial electromechanical delay for atrial fibrillation recurrence. | We investigated the predictive value of atrial electromechanical delay (AEMD) for recurrence of atrial fibrillation (AF) at 1-month after cardioversion.</AbstractText>Seventy-seven patients with persistent AF were evaluated and finally 50 patients (12 men, 38 women) were included. All patients underwent transthoracic e... |
12,355 | Is abnormal myocardial repolarization associated with the occurrence of malignant tachyarrhythmias in Takotsubo cardiomyopathy? | Abnormalities of cardiac repolarization are a hallmark of Takotsubo cardiomyopathy (TC), but their association with the occurrence of syncope and ventricular tachyarrhythmias is unknown. This study sought to assess the relationship between myocardial repolarization and malignant tachyarrhythmias in TC.</AbstractText>Cl... |
12,356 | Mechanical ventilation in the early phase of ST elevation myocardial infarction treated with mechanical revascularization. | So far, few data have been available on the incidence and outcome of patients with acute myocardial infarction (MI) requiring mechanical ventilation (MV). The aim of the study was to assess the clinical and prognostic impact of MV at short and long term in 106 patients with ST elevation MI (STEMI) requiring mechanical ... |
12,357 | Clinical implications of left ventricular assist device implantation in patients with an implantable cardioverter-defibrillator. | This study aims to study the clinical implications of the concomitant use of a left ventricular assist device (LVAD) and an implantable cardioverter-defibrillator (ICD).</AbstractText>In this retrospective study, all patients who underwent LVAD (Heart Mate II) implantation with concomitant ICD therapy at our institutio... |
12,358 | The importance of non-uniformities in mechano-electric coupling for ventricular arrhythmias. | Cardiac mechanical and electrical activities are tightly linked through an intra-cardiac regulatory loop (mechano-electric coupling). This connection is essential for normal heart function and auto-regulation. In diseases associated with altered myocardial mechanical properties or function, however, feedback from the m... |
12,359 | Surgical myectomy improves pulmonary hypertension in obstructive hypertrophic cardiomyopathy. | Characterization of pulmonary hypertension (PH) and the effects of myectomy in hypertrophic cardiomyopathy (HCM) remain poorly defined. The aim of the study was to investigate the effect of myectomy on PH in HCM.</AbstractText>This is a retrospective analysis of 306 consecutive symptomatic HCM patients (70% NYHA class ... |
12,360 | Right ventricular apical pacing-induced left ventricular dyssynchrony is associated with a subsequent decline in ejection fraction. | In patients with normal left ventricular (LV) ejection fraction (EF), the interposition of chronic, high-dose right ventricular apical (RVA) pacing may produce late EF decline.</AbstractText>To test the hypothesis that LV dyssynchrony, defined echocardiographically and apparent early after interposition of pacing, woul... |
12,361 | Patients treated with catheter ablation for ventricular tachycardia after an ICD shock have lower long-term rates of death and heart failure hospitalization than do patients treated with medical management only. | Ventricular arrhythmias in patients with implantable cardioverter-defibrillators (ICDs) adversely affect outcomes. Antiarrhythmic approaches to ventricular tachycardia (VT) have variable efficacy and may increase risk of ventricular arrhythmias, worsening cardiomyopathy, and death. Comparatively, VT ablation is an alte... |
12,362 | J wave elevation to monitor quinidine efficacy in early repolarization syndrome. | We present the case of a 14-year-old female with early repolarization syndrome who presented with recurrent ventricular fibrillation and ICD shocks which were refractory to multiple drugs and catheter ablation. Treatment with quinidine, an Ito blocker, resulted in a normalization of J waves and suppression of VF. Inter... |
12,363 | Fate of functional tricuspid regurgitation in aortic stenosis after aortic valve replacement. | Functional tricuspid regurgitation (TR) is found not infrequently in conjunction with aortic stenosis. The aim of the present study was to evaluate the changes in TR and to identify the predictors of late progression after aortic valve replacement.</AbstractText>We evaluated 354 patients who had undergone aortic valve ... |
12,364 | [Effects of noninvasive positive pressure ventilation on patients with arrhythmia complicated by sleep apnea syndrome]. | To investigate the clinical efficacy of noninvasive positive pressure ventilation (NPPV) in treatment of patients with arrhythmia complicated by sleep apnea syndrome (SAS).</AbstractText>One hundred and thirty-five arrhythmia patients with polysomnography diagnosed SAS were randomly divided into NPPV group (69 cases) a... |
12,365 | [Important changes in the Dutch College of General Practitioners (NHG) practice guideline 'Atrial fibrillation': revised practice guideline issued]. | A small number of points in the NHG practice guideline 'Atrial fibrillation' have been reviewed; this has important consequences for general practice. The risk of ischaemic CVA in patients with atrial fibrillation is determined using a new risk score (CHA2DS2-VASc). The target value of the resting ventricular frequency... |
12,366 | VLCAD deficiency in a patient who recovered from ventricular fibrillation, but died suddenly of a respiratory syncytial virus infection. | VLCAD deficiency is an autosomal recessive disorder caused by a defect of fatty acid oxidation. The phenotype is classified into three clinical forms on the basis of the onset of symptoms: a severe form with neonatal onset; a milder form with childhood onset; and a late-onset form. The neonatal form is the most common,... |
12,367 | Inefficacy of a highly selective T-type calcium channel blocker in preventing atrial fibrillation related remodeling. | The T-type Ca(2+) channel (I(CaT)) blocker mibefradil prevents AF-promoting remodeling occurring with atrial tachycardia, an action that has been attributed to I(CaT) inhibition. However, mibefradil has other effects, including ability to inhibit L-type Ca(2+) channels, Na(+) channels and cytochromes. Thus, the relatio... |
12,368 | An evolving story of angiotensin-II-forming pathways in rodents and humans. | Lessons learned from the characterization of the biological roles of Ang-(1-7) [angiotensin-(1-7)] in opposing the vasoconstrictor, proliferative and prothrombotic actions of AngII (angiotensin II) created an underpinning for a more comprehensive exploration of the multiple pathways by which the RAS (renin-angiotensin ... |
12,369 | Using dominant eigenvalue analysis to predict formation of alternans in the heart. | Ventricular fibrillation at the whole heart level is often preceded by the alternation of action potential duration (APD), i.e., alternans, at the cellular level. As proven in many experiments, traditional approaches based on the slope of the restitution curve have not been successful in predicting alternans formation.... |
12,370 | Blunt cardiac injury with scintigraphic perfusion-metabolism mismatch. | A healthy 37-year-old man who bruised his chest with a steel frame developed ventricular fibrillation, pulseless ventricular tachycardia, and temporary torsade de pointes, and was resuscitated with emergency medical treatment. Thallium 201 scintigraphy 7 days later revealed a defect only in a small area of the apex, wh... |
12,371 | A case of primary aldosteronism who experienced cardiopulmonary arrest, was resuscitated and cured. | A 45-year-old female went into cardiopulmonary arrest. She was in ventricular fibrillation (VF) and was defibrillated using an automated external defibrillator. After arrival at our hospital, electrocardiography monitoring showed QT prolongation. Serum potassium was low at 2.2 mEq/L, and hypokalemia-induced long Q... |
12,372 | Anomalous origin of the left coronary artery from pulmonary artery a late presentation-Case report and review of literature. | An otherwise healthy 26-year-old female presented with sudden cardiac arrest. She was resuscitated with unsynchronized cardioversion for ventricular fibrillation. A left heart cardiac catheterization showed anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA). Cardiac computed tomographic ang... |
12,373 | Post-operative simultaneous very late two-vessel drug eluting stent thrombosis with sparing of bare metal stent in a Jehovah's witness after clopidogrel withdrawal. | Very late stent thrombosis is a feared complication after drug-eluting stent (DES) implantation. Several factors related to the patient, generation and type of the deployed stent, procedure, and premature antiplatelet withdrawal are known to contribute to this complication. Herein, we describe a case of a Jehovah's wit... |
12,374 | Anaphylactic shock associated with intravenous amiodarone. | A 64-year-old woman was admitted to our emergency department with shortness of breath and palpitation which started 2 h before her admission. She had a history of rheumatic mitral valve disease and was on drug treatment with warfarin and metoprolol. The patient was orthopneic, blood pressure was 108/68 mmHg w... |
12,375 | Percutaneous balloon dilation of severe pulmonary valve stenosis in patients with cyanosis and congestive heart failure. | This article reports outcomes of percutaneous balloon dilation in patients with severe pulmonary valve stenosis, in particular in those treated late with cyanosis, congestive heart failure, and pericardial effusion.</AbstractText>Percutaneous balloon dilation is the treatment of choice for pulmonary valve stenosis. Alt... |
12,376 | Evaluation of pre-hospital administration of adrenaline (epinephrine) by emergency medical services for patients with out of hospital cardiac arrest in Japan: controlled propensity matched retrospective cohort study. | To evaluate the effectiveness of pre-hospital adrenaline (epinephrine) administered by emergency medical services to patients with out of hospital cardiac arrest.</AbstractText>Controlled propensity matched retrospective cohort study, in which pairs of patients with or without (control) adrenaline were created with a s... |
12,377 | Cardiac arrest during anesthesia at a university Hospital in Nigeria. | We assessed the incidence and outcomes of cardiac arrest during anesthesia in the operating room at our university hospital. A previous study on intraoperative cardiac arrests covered a period from 1994-1998 and since then; anesthetic personnel, equipment, and workload have increased remarkably.</AbstractText>After obt... |
12,378 | [The pacemaker and implantable cardioverter-defibrillator registry of the Italian Association of Arrhythmology and Cardiac Pacing - Annual Report 2012]. | The pacemaker (PM) and implantable cardioverter-defibrillator (ICD) Registry of the Italian Association of Arrhythmology and Cardiac Pacing (AIAC) monitors the main epidemiological data in real-world practice. The survey for the 2012 activity collects information about demographics, clinical characteristics, main indic... |
12,379 | Reversible cardiomyopathy after radiofrequency ablation of 30-year persistent atrial tachycardia. | Tachycardia-induced cardiomyopathy (TIC) is a reversible form of the left ventricular (LV) systolic dysfunction and is believed to be a relatively acute process. We report a TIC case with a 30-year history of long-lasting persistent atrial tachycardia involving a 44-year-old man previously diagnosed with dilated cardio... |
12,380 | Pilot evaluation of an integrated monitor-adhesive patch for long-term cardiac arrhythmia detection in India. | Electrocardiographic monitoring represents one of the most reliable and time-tested methods for reducing ambiguity in cardiac arrhythmia diagnosis. In India, the resting ECG is generally the first tool of choice for in-clinic diagnosis. The external loop recorder (ELR) is another useful tool that compounds the advantag... |
12,381 | Changes in left ventricular filling in patients with persistent atrial fibrillation. | Former studies showed possible interrelationship between altered ventricular filling patterns and atrial fibrillation (AF).</AbstractText>Long term persistent AF has a negative impact on left ventricular filling in patients with preserved ejection fraction of left ventricle.</AbstractText>Our study was designed as a pr... |
12,382 | A translational approach to probe the proarrhythmic potential of cardiac alternans: a reversible overture to arrhythmogenesis? | Electrocardiographic alternans, a phenomenon of beat-to-beat alternation in cardiac electrical waveforms, has been implicated in the pathogenesis of ventricular arrhythmias and sudden cardiac death (SCD). In the clinical setting, a positive microvolt T-wave alternans test has been associated with a heightened risk of a... |
12,383 | Totally endoscopic robotic coronary artery bypass surgery. | To assess the current status and methods of robotic totally endoscopic coronary artery bypass (TECAB) surgery and discuss important anesthetic considerations.</AbstractText>Technological and surgical advances in robotics have led to the evolution of TECAB surgery from a single-vessel procedure to quadruple-vessel bypas... |
12,384 | Effect of preoperative symptoms on outcomes after valve repair for degenerative aortic insufficiency. | This study evaluated the effect of preoperative symptoms on long-term survival and valve reintervention in patients undergoing aortic valve repair (AVr) for severe degenerative aortic insufficiency (AI).</AbstractText>Between March 1996 and June 2010, 274 patients underwent AVr for severe AI. Seventy-seven were perform... |
12,385 | Inappropriate subcutaneous implantable cardioverter-defibrillator shocks due to T-wave oversensing can be prevented: implications for management. | Inappropriate shocks (IASs) complicate implantable cardioverter-defibrillator (ICD) therapy. The management of IASs in patients with a subcutaneous ICD (S-ICD) differs from that in patients with a conventional ICD because of different sensing algorithms and programming options.</AbstractText>To describe the management ... |
12,386 | Nonsense-mediated mRNA decay due to a CACNA1C splicing mutation in a patient with Brugada syndrome. | Brugada syndrome (BrS) is an inherited cardiac arrhythmia associated with sudden death due to ventricular fibrillation. Mutations in genes related to the cardiac L-type calcium channel have been reported to be causative of BrS. Generally, the messenger RNA (mRNA) that contains a nonsense mutation is rapidly degraded vi... |
12,387 | Left atrial booster-pump function as a predictive parameter for new-onset postoperative atrial fibrillation in patients with severe aortic stenosis. | Postoperative atrial fibrillation (POAF) is associated with increased risk of embolic events and heart failure, but its associated factors remains unknown. Left atrial (LA) subclinical mechanical dysfunction caused by the acute stress of surgery may be clinically manifested as POAF. The purpose of our study was therefo... |
12,388 | Pulmonary arterial systolic pressure and E/e' in the evaluation of left ventricular filling pressure: assessment of patients with atrial fibrillation. | Echocardiographic assessments including E/e' are a good predictor of elevated left ventricular (LV) filling pressure during sinus rhythm. However, the evaluation of LV filling pressure using classic echocardiographic assessment has been challenging in the setting of atrial fibrillation (AF). The aim of this study was t... |
12,389 | SCN5A mutation in Chinese patients with arrhythmogenic right ventricular dysplasia. | Arrhythmogenic right ventricular dysplasia (ARVD) is a genetically determined disorder, characterized by two components: cardiomyopathy and arrhythmia. To date, the ion channel-related pathogenesis underlying this phenomenon has been poorly understood. The aim of this study was to systematically evaluate the sodium cha... |
12,390 | Left ventricular geometry and outcomes in patients with atrial fibrillation: the AFFIRM Trial. | Echocardiographically determined left ventricular hypertrophy (LVH) is a marker of cardiovascular disease related to prognosis and clinical outcomes. We sought to determine if LVH is a measure of outcomes in atrial fibrillation (AF) patients.</AbstractText>We performed a post-hoc analysis of patients with echocardiogra... |
12,391 | Early repolarization, acute emotional stress and sudden death. | We herein report the case of a 36-year-old man who died suddenly after a fight with another man. Forensic investigations included unenhanced computed tomography, postmortem angiography, autopsy, histology, neuropathology, toxicology, and biochemistry and allowed a traumatic cause of death to be excluded. An electrocard... |
12,392 | Obesity is associated with lower coronary microvascular density. | Obesity is associated with diastolic dysfunction, lower maximal myocardial blood flow, impaired myocardial metabolism and increased risk of heart failure. We examined the association between obesity, left ventricular filling pressure and myocardial structure.</AbstractText>We performed histological analysis of non-isch... |
12,393 | Ventricular remodelling in rabbits with sustained high-fat diet. | Excess weight gain and obesity are one of the most serious health problems in the western societies. These conditions enhance risk of cardiac disease and have been linked with increased prevalence for cardiac arrhythmias and sudden death. Our goal was to study the ventricular remodelling occurring in rabbits fed with h... |
12,394 | Risk of sudden cardiac death. | The aim of this study was to determine characteristics of patients with sudden cardiac arrest (SCA) and/or sudden cardiac death (SCD). We need an effective risk stratification method for SCD in patients without low left ventricular ejection fraction (LVEF).</AbstractText>The study population of this cross-sectional stu... |
12,395 | Left atrial structure and function in atrial fibrillation: ENGAGE AF-TIMI 48. | The complex relationship between left atrial (LA) structure and function, electrical burden of atrial fibrillation (AF) and stroke risk is not well understood. We aimed to describe LA structure and function in AF.</AbstractText>Left atrial structure and function was assessed in 971 subjects enrolled in the echocardiogr... |
12,396 | Does a high percentage of right ventricular pacing influence the incidence of paroxysmal atrial fibrillation in myotonic dystrophy type 1 patients? | Paroxysmal atrial tachyarrhythmias occur frequently in myotonic dystrophy type 1 (MD1) patients. Pacemakers, implanted for the treatment of bradyarrhythmias and including detailed diagnostic functions, may facilitate the diagnosis and management of frequent paroxysmal atrial fibrillation (AF) that may remain undetected... |
12,397 | Overexpression of KCNN3 results in sudden cardiac death. | A recent genome-wide association study identified a susceptibility locus for atrial fibrillation at the KCNN3 gene. Since the KCNN3 gene encodes for a small conductance calcium-activated potassium channel, we hypothesized that overexpression of the SK3 channel increases susceptibility to cardiac arrhythmias.</AbstractT... |
12,398 | Delirium in patients admitted to a cardiac intensive care unit with cardiac emergencies in a developing country: incidence, prevalence, risk factor and outcome. | To assess the incidence, prevalence, risk factors and outcome of delirium in patients admitted to a cardiac intensive care unit (ICU) of a tertiary care hospital.</AbstractText>Three hundred nine consecutive patients admitted to a 22-bed coronary care unit were screened for presence of delirium by using Confusion Asses... |
12,399 | Cardioverter-defibrillator implantation in myeloma-associated cardiac amyloidosis. | A 62-year-old woman with multiple myeloma and light-chain amyloidosis with significant heart involvement developed an in-hospital cardiac arrest. After cardiopulmonary resuscitation, a stable sinus rhythm without any cerebral damage was restored, and the patient was admitted to the coronary care unit. A cardioverter-de... |
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