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12,400 | Evaluation of the safety and effectiveness of the CryoMedix cryoablation catheter system for the treatment of atrial flutter and fibrillation. | Catheter ablation of atrial flutter and fibrillation (AFL and AF) has typically been performed with radiofrequency energy. Cryoablation has recently been used for AF and AFL, but its success has been limited by the nadir temperature achievable using nitrous oxide as a refrigerant. In this study, a novel approach allowi... |
12,401 | A support vector machine for predicting defibrillation outcomes from waveform metrics. | Algorithms to predict shock success based on VF waveform metrics could significantly enhance resuscitation by optimising the timing of defibrillation.</AbstractText>To investigate robust methods of predicting defibrillation success in VF cardiac arrest patients, by using a support vector machine (SVM) optimisation appr... |
12,402 | Shockable rhythms and defibrillation during in-hospital pediatric cardiac arrest. | To analyze the results of cardiopulmonary resuscitation (CPR) that included defibrillation during in-hospital cardiac arrest (IH-CA) in children.</AbstractText>A prospective multicenter, international, observational study on pediatric IH-CA in 12 European and Latin American countries, during 24 months. Data from 502 ch... |
12,403 | Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts. | Enhanced late inward Na current (INa-L) modulates action potential duration (APD) and plays a key role in the genesis of early afterdepolarizations (EADs) and delayed afterdepolarizations (DADs) and triggered activity.</AbstractText>The purpose of this study was to define the influence of selective block of INa-L on EA... |
12,404 | Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia. | The aim of this study was to investigate the modulatory effect of the coxsackie and adenovirus receptor (CAR) on ventricular conduction and arrhythmia vulnerability in the setting of myocardial ischemia.</AbstractText>A heritable component in the risk of ventricular fibrillation during myocardial infarction has been we... |
12,405 | Novel insight into the natural history of short QT syndrome. | This study intends to gain further insights into the natural history, the yield of familial and genetic screening, and the arrhythmogenic mechanisms in the largest cohort of short QT syndrome (SQTS) patients described so far.</AbstractText>SQTS is a rare genetic disorder associated with life-threatening arrhythmias, an... |
12,406 | Myocardial extracellular volume expansion and the risk of recurrent atrial fibrillation after pulmonary vein isolation. | This study tested whether myocardial extracellular volume (ECV) is increased in patients with hypertension and atrial fibrillation (AF) undergoing pulmonary vein isolation and whether there is an association between ECV and post-procedural recurrence of AF.</AbstractText>Hypertension is associated with myocardial fibro... |
12,407 | Exercise echocardiography in asymptomatic HCM: exercise capacity, and not LV outflow tract gradient predicts long-term outcomes. | This study sought to assess long-term outcomes in asymptomatic or minimally symptomatic patients with hypertrophic cardiomyopathy (HCM) who underwent exercise echocardiography, without invasive therapies for relief of left ventricular outflow tract (LVOT) obstruction.</AbstractText>Many HCM patients present with LVOT o... |
12,408 | Adjuvant antiarrhythmic therapy in patients with implantable cardioverter defibrillators. | The risk of sudden cardiac death from ventricular fibrillation or ventricular tachycardia in patients with cardiomyopathy related to structural heart disease has been favorably impacted by the wide adaptation of implantable cardioverter defibrillators (ICDs) for both primary and secondary prevention. Unfortunately, aft... |
12,409 | Electrocardiogram pattern recognition and analysis based on artificial neural networks and support vector machines: a review. | Computer systems for Electrocardiogram (ECG) analysis support the clinician in tedious tasks (e.g., Holter ECG monitored in Intensive Care Units) or in prompt detection of dangerous events (e.g., ventricular fibrillation). Together with clinical applications (arrhythmia detection and heart rate variability analysis), E... |
12,410 | Relation of autonomic and cardiac abnormalities to ventricular fibrillation in a rat model of epilepsy. | Cardiac autonomic, conduction, and structural changes may occur in epilepsy and may contribute to sudden unexpected death in epilepsy (SUDEP), e.g. by increasing the risk for ventricular fibrillation (VF). In a model of chronic seizures in rats, we sought to study (1) cardiac and autonomic derangements that accompany t... |
12,411 | Arrhythmias and heart failure. | Atrial fibrillation and ventricular tachyarrhythmias are frequently seen in patients with heart failure, and complicate the management of such patients. Both types of arrhythmia lead to increased morbidity and mortality, and often prove to be challenging issues to manage. The many randomized studies that have been perf... |
12,412 | [Clinical features and management of complete heart block after transaortic extended septal myectomy in patients with hypertrophic obstructive cardiomyopathy]. | To analyze the clinical features, precaution and management of complete heart block (CHB) after transaortic extended septal myectomy operation (extended Morrow procedure) in patients with hypertrophic obstructive cardiomyopathy (HOCM).</AbstractText>From October 1996 to December 2011, 10[6 men; mean age (45.4 ± 15... |
12,413 | [Types and risk factors of arrhythmia on young patients with acute coronary syndrome in Henan province]. | The types and risk factors of arrhythmia were analyzed on acute coronary syndrome (ACS) patients under the age of 44 years who were hospitalized in Henan province between September 2009 to June 2012.</AbstractText>Medical records of eligible patients were obtained from the information system of the First Affiliated Hos... |
12,414 | Magnesium: the forgotten electrolyte. | Magnesium (Mg++), Potassium (K+) and Calcium (CA++) are important electrolytes in keeping a stable electrical status. The purpose of this study was to measure them in critically ill patients.</AbstractText>We evaluated the electrolytes in 28 consecutive patients. Eighteen were females and 10 males with mean age of 62 +... |
12,415 | Three cases of corticosteroid therapy triggering ventricular fibrillation in J-wave syndromes. | We describe three cases of J-wave syndrome in which ventricular fibrillation (VF) was probably induced by corticosteroid therapy. The patients involved were being treated with prednisolone for concomitant bronchial asthma. One of the three patients had only one episode of VF during her long follow-up period (14 years).... |
12,416 | Prognostic difference between paroxysmal and non-paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy. | The association of atrial fibrillation (AF) with sudden death and the difference in prognostic significance between paroxysmal and non-paroxysmal AF remains unclear in patients with hypertrophic cardiomyopathy (HCM). Our aim was to investigate the clinical significance of AF, and to assess the prognostic difference bet... |
12,417 | Prevalence and the long-term prognosis of functional mitral regurgitation in Japanese patients with symptomatic heart failure. | Functional mitral regurgitation (FMR) is a common and critical condition in patients with heart failure (HF); however, the prevalence and clinical outcome of FMR in Japanese real-world clinical practice remain unclear. Within a single hospital-based cohort in the Shinken Database 2004-2011, which comprised all new pati... |
12,418 | Electrocardiographic J waves are associated with right ventricular morphology and function: evaluation by cardiac magnetic resonance imaging. | We assessed the relationship between J waves and the ventricular morphology and function using cardiac magnetic resonance imaging (MRI). The 12-lead electrocardiograms (ECGs) of 105 consecutive patients who underwent cardiac MRI were reviewed, and those with signs of arrhythmogenic right ventricular cardiomyopathy, com... |
12,419 | Effect of sleep apnea and continuous positive airway pressure on cardiac structure and recurrence of atrial fibrillation. | Sleep apnea (SA) is associated with an increased risk of atrial fibrillation (AF). We sought to determine the effect of SA on cardiac structure in patients with AF, whether therapy for SA was associated with beneficial cardiac structural remodelling, and whether beneficial cardiac structural remodelling translated into... |
12,420 | Electrocardiogram frequency change by extracorporeal blood perfusion in a swine ventricular fibrillation model. | Extracorporeal cardiopulmonary resuscitation (ECPR) refers to the application of extracorporeal blood circulation with oxygenation as a resuscitation tool. The objective of this study is to observe the frequency component changes in the electrocardiogram (ECG) by ECPR during prolonged ventricular fibrillation (VF).</Ab... |
12,421 | Design of the PRINCESS trial: pre-hospital resuscitation intra-nasal cooling effectiveness survival study (PRINCESS). | Therapeutic hypothermia (TH, 32-34°C) has been shown to improve neurological outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA) with ventricular tachycardia or fibrillation. Earlier initiation of TH may increase the beneficial effects. Experimental studies have suggested that starting TH during... |
12,422 | Hyperthyroidism and cardiovascular complications: a narrative review on the basis of pathophysiology. | Cardiovascular complications are important in hyperthyroidism because of their high frequency in clinical presentation and increased mortality and morbidity risk. The cause of hyperthyroidism, factors related to the patient, and the genetic basis for complications are associated with risk and the basic underlying mecha... |
12,423 | Left thoracoscopic sympathectomy for cardiac denervation in patients with life-threatening ventricular arrhythmias. | We reported the outcomes of a single-institution experience using video-assisted thoracoscopic left cardiac sympathetic denervation as an adjunctive therapeutic technique in pediatric and young adult patients with life-threatening ventricular arrhythmias.</AbstractText>We conducted a retrospective clinical review of al... |
12,424 | Maze procedure in patients with left ventricular dysfunction. | The risks and benefits of a concomitant Maze procedure for patients with LV dysfunction undergoing major cardiac surgery have not yet been elucidated. This study aimed to evaluate the clinical impacts of the Maze procedure in patients with atrial fibrillation and left ventricular (LV) dysfunction.</AbstractText>Between... |
12,425 | Very prolonged episode of self-terminating ventricular fibrillation in a patient with Brugada syndrome. | We report the case of a very prolonged spontaneous episode of self-terminating ventricular fibrillation in a patient with Brugada syndrome (BrS). The patient first underwent implantation of an internal loop recorder after an episode of prolonged loss of consciousness (several minutes) that was suggestive of a nonarrhyt... |
12,426 | Predictors of mortality in patients with an implantable cardiac defibrillator: a systematic review and meta-analysis. | Many current predictors of mortality in heart failure (HF) were evaluated before the use of implantable cardioverter defibrillators (ICDs). We conducted a meta-analysis to identify factors associated with mortality in ICD-HF patients.</AbstractText>We searched in MedLine, EMBASE, and CINAHL in May 2012. Two reviewers s... |
12,427 | The risk of adverse events associated with atropine administration during dobutamine stress echocardiography in cardiac transplant patients: a 28-year single-center experience. | Although dobutamine stress echocardiography (DSE) is performed in heart transplant patients, the safety profile of atropine administration in DSE in this setting is unclear.</AbstractText>We identified heart transplant patients who received atropine during DSE from January 1984 to August 2011 at our institution and com... |
12,428 | Polymorphic ventricular tachycardia--part II: the channelopathies. | In this article, we explore the clinical and cellular phenomena of primary electrical diseases of the heart, that is, conditions purely related to ion channel dysfunction and not structural heart disease or reversible acquired causes. This growing classification of conditions, once considered together as "idiopathic ve... |
12,429 | Severe hypokalemia probably associated with sertraline use. | To report a case of ventricular fibrillation caused by severe hypokalemia probably associated with sertraline use.</AbstractText>A 48-year-old male patient experienced ventricular fibrillation and cardiac arrest 2 hours after an uneventful coronary angiography procedure, which revealed normal, unobstructed coronary art... |
12,430 | Assessment of adverse events and predictors of neurological recovery after therapeutic hypothermia. | Therapeutic hypothermia improves neurological recovery after witnessed cardiac arrest from ventricular fibrillation or tachycardia. Its application is expanding despite associated adverse events.</AbstractText>To assess the occurrence of adverse events and predictors of good versus poor neurological recovery after ther... |
12,431 | Incidence of sudden cardiac death after ventricular fibrillation complicating acute myocardial infarction: a 5-year cause-of-death analysis of the FAST-MI 2005 registry. | Limited data are available on long-term prognosis or causes-of-death analysis among survivors of acute myocardial infarction (MI) according to whether or not they developed ventricular fibrillation (VF) during the acute stage of MI.</AbstractText>Among 3670 MI patients hospitalized in France in 2005 and enrolled in thi... |
12,432 | Ibandronate and ventricular arrhythmia risk. | Bisphosphonates, including ibandronate, are used in the prevention and treatment of osteoporosis.</AbstractText>We report a case of suspected ibandronate-associated arrhythmia, following a single dose of ibandronate in a 55-year-old female. ECG at presentation revealed frequent ectopy and QT/QTc interval prolongation; ... |
12,433 | Preventive Effects of the Angiotensin-II Receptor Blocker on Atrial Remodeling in an Ischemic Heart Failure Model of Rats. | It is widely known that angiotensin-II receptor blockers (ARBs) have reverse remodeling effects in atrium. Although atrial fibrillation is frequent in ischemic heart failure clinically, experiments to demonstrate ARB's effects on atrial remodeling in a heart failure model are rare.</AbstractText>A heart failure model a... |
12,434 | Postoperative Atrial Fibrillation following Open Cardiac Surgery: Predisposing Factors and Complications. | New-onset postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery that has substantial effects on outcomes. The aim of this study is to analyze the risk factors in the pre, intra, and postoperative periods, and evaluate its impact on patients' outcome.</AbstractText>In this prospective stud... |
12,435 | Neurological outcomes in patients transported to hospital without a prehospital return of spontaneous circulation after cardiac arrest. | As emergency medical services (EMS) personnel in Japan are not allowed to perform termination of resuscitation in the field, most patients experiencing an out-of-hospital cardiac arrest (OHCA) are transported to hospitals without a prehospital return of spontaneous circulation (ROSC). As the crucial prehospital factors... |
12,436 | Sudden cardiac arrest in hemodialysis patients with wearable cardioverter defibrillator. | The survival outcome following a sudden cardiac arrest (SCA) in hemodialysis (HD) patients is poor regardless of whether an event takes place in or out of a dialysis center. The characteristics of SCA and post-SCA survival with HD patients using a wearable cardioverter defibrillator (WCD) are unknown.</AbstractText>All... |
12,437 | Acute administration of natural honey protects isolated heart in normothermic ischemia. | This study intended to assess the efficacy of acute administration of natural honey on cardiac arrhythmias and infarct size when it is used during the normothermic ischemia in isolated rat heart. During 30 min of regional normothermic ischemia followed by 120 min of reperfusion, the isolated hearts were perfused by a m... |
12,438 | Prolonged Oral Administration of Oleuropein Might Protect Heart against Aconitine-induced Arrhythmia. | In this study, it was surveyed to know whether an oral single dose of oleuropein could mimic the cardiac preconditioning in rats' hearts or whether its prolonged oral administration could protect the heart against the aconitine-induced arrhythmia in rats. Eighty male Wistar rats were divided into two series (n = 8 in e... |
12,439 | Therapeutic peritoneal lavage with warm saline solution as an option for a critical hypothermic trauma patient. | In this paper, we present the case of a 63-year-old woman, who was found in her flat lying unconscious on the floor for an unknown time. At the time of admission, her core temperature was 24 °C and ventricular fibrillation was detected on the electrocardiogram (ECG). Because of the unstable conditions, the ... |
12,440 | Prognosis of in-hospital myocardial infarction course for diabetic and nondiabetic patients using a noninvasive evaluation of hemodynamics and heart rate variability. | The objective of our study was to investigate whether the combination of markers of heart rate variability (HRV) and impedance cardiography (ICG) help evaluate the risk of in-hospital death, ventricular arrhythmia, or complicated course secondary to myocardial infarction (STEMI) and to clarify whether combined analysis... |
12,441 | Implantable cardioverter-defibrillator therapy before death: high risk for painful shocks at end of life. | Several trials have demonstrated improved survival with implantable cardioverter-defibrillator (ICD) therapy. The cause and nature of death in the ICD population have been insufficiently investigated. The objective of this study was to analyze ICDs from deceased patients to assess the incidence of ventricular tachyarrh... |
12,442 | Long-duration ventricular fibrillation exhibits 2 distinct organized states. | Previous studies showed that endocardial activation during long-duration ventricular fibrillation (VF) exhibits organized activity. We identified and quantified the different types of organized activity.</AbstractText>Two 64-electrode basket catheters were inserted, respectively, into the left ventricle and right ventr... |
12,443 | The role of Interleukin-6, its -174 G>C polymorphism and C-reactive protein in idiopathic cardiac arrhythmias in children. | ABSTRACT Purpose: Knowledge about the role of inflammation in the pathogenesis of arrhythmias in children is limited. Several studies have suggested a relationship between plasma IL-6 levels and/or the -174G>C IL-6 gene polymorphism and atrial fibrillation in adults. Our present study was performed to investigate wh... |
12,444 | Ventricular pacing on the prognosis of patients with pacemaker implantation. | Excessive right ventricular apex pacing has significant adverse effects on the cardiac function and hence, it is necessary to clinically optimize pacing parameters and advocate suitable physiological pacing to safeguard the cardiac function after pacemaker implant. Minimizing ventricular pacing is an atrioventricular n... |
12,445 | Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial. | Hospital cooling improves outcome after cardiac arrest, but prehospital cooling immediately after return of spontaneous circulation may result in better outcomes.</AbstractText>To determine whether prehospital cooling improves outcomes after resuscitation from cardiac arrest in patients with ventricular fibrillation (V... |
12,446 | Detection of life-threatening arrhythmias using feature selection and support vector machines. | Early detection of ventricular fibrillation (VF) and rapid ventricular tachycardia (VT) is crucial for the success of the defibrillation therapy. A wide variety of detection algorithms have been proposed based on temporal, spectral, or complexity parameters extracted from the ECG. However, these algorithms are mostly c... |
12,447 | Evolution of clinical diagnosis in patients presenting with unexplained cardiac arrest or syncope due to polymorphic ventricular tachycardia. | A systematic evaluation of patients with unexplained cardiac arrest (UCA) yields a diagnosis in 50% of the cases. However, evolution of clinical phenotype, identification of new disease-causing mutations, and description of new syndromes may revise the diagnosis.</AbstractText>To assess the evolution in diagnosis among... |
12,448 | Phased RF ablation in persistent atrial fibrillation. | Persistent and long-standing persistent atrial fibrillation (AF) often requires extensive and/or repeat radiofrequency (RF) ablation procedures.</AbstractText>The Tailored Treatment of Persistent Atrial Fibrillation (TTOP-AF) study assessed the effectiveness and safety of the phased RF system in a randomized controlled... |
12,449 | Addition of glucagon to adrenaline improves hemodynamics in a porcine model of prolonged ventricular fibrillation. | Cardiac arrest is a daunting medical emergency. The aim of the present study was to assess whether the combination of adrenaline and glucagon would improve initial resuscitation success, 48-hour survival, and neurologic outcome compared with adrenaline alone in a porcine model of ventricular fibrillation.</AbstractText... |
12,450 | Dantrolene suppresses ventricular ectopy and arrhythmogenicity with acute myocardial infarction in a langendorff-perfused pacing-induced heart failure rabbit model. | Dantrolene prevents arrhythmogenic Ca(2+) release during heart failure (HF). However, direct evidence to support its antiarrhythmic effects in failing hearts with acute myocardial infarction (AMI) is lacking.</AbstractText>HF was induced by right ventricular pacing (312 beats/min, 4 weeks) in 19 rabbits. AMI was induce... |
12,451 | Low mortality and low rate of perceived and documented arrhythmias after Cox maze III surgery for atrial fibrillation. | To report a long-term single-site experience of the cut-and-sew Cox maze III procedure for atrial fibrillation (AF).</AbstractText>A total of 232 consecutive patients underwent the Cox maze III procedure for symptomatic therapy-refractory AF, with concomitant surgery in 34 patients. Follow-up data were obtained from el... |
12,452 | Evaluation of time course and predicting factors of progression of paroxysmal or persistent atrial fibrillation to permanent atrial fibrillation. | To evaluate time course and predictors of progression of paroxysmal or persistent atrial fibrillation (AF) to permanent AF.</AbstractText>We included 460 patients referred for paroxysmal (n = 337) or persistent (n = 123) AF between 1994 and 2012. Mean follow-up was 13.2 ± 6.5 years. AF progress... |
12,453 | Comparative evaluation of methodologies for T-wave alternans mapping in electrograms. | Electrograms (EGM) recorded from the surface of the myocardium are becoming more and more accessible. T-wave alternans (TWA) is associated with increased vulnerability to ventricular tachycardia/fibrillation and it occurs before the onset of ventricular arrhythmias. Thus, accurate methodologies for time-varying alterna... |
12,454 | Conductive channels identified with contrast-enhanced MR imaging predict ventricular tachycardia in systolic heart failure. | This study evaluated whether the conductive channel (CC) identified by late gadolinium enhanced-cardiac magnetic resonance (LGE-CMR) is associated with ventricular tachycardia (VT) in patients with systolic heart failure (HF).</AbstractText>One recent study demonstrated that the CC formed by heterogeneous tissue within... |
12,455 | [Effects of cardiac resynchronization therapy in patients with advanced congestive heart failure evaluated by real-time 3-dimensional echocardiography]. | To quantitatively assess the effects of cardiac resynchronization therapy (CRT) in patients with advanced congestive heart failure by real-time 3-dimensional(3D) echocardiography (RT-3DE).</AbstractText>Eighteen patients with advanced congestive heart failure underwent CRT with New York Heart association(NYHA) class II... |
12,456 | Congenital and hereditary causes of sudden cardiac death in young adults: diagnosis, differential diagnosis, and risk stratification. | Sudden cardiac death is defined as death from unexpected circulatory arrest-usually a result of cardiac arrhythmia-that occurs within 1 hour of the onset of symptoms. Proper and timely identification of individuals at risk for sudden cardiac death and the diagnosis of its predisposing conditions are vital. A careful hi... |
12,457 | Untreated preoperative depression is not associated with postoperative arrhythmias in CABG patients. | The mechanism by which depression affects postoperative outcome may involve arrhythmias. The purpose of this study was to evaluate whether untreated depression is associated with an increased incidence of postoperative arrhythmias in patients undergoing coronary artery bypass graft surgery (CABG).</AbstractText>One hun... |
12,458 | A less aggressive therapeutic option for electrical storm. | Electrical storm (ES) describes the rapidly clustering ventricular fibrillation (VF) that requires multiple cardioversions. Emerging evidence suggests that Purkinje arborization and sympathetic nerve regeneration play a major role in initiating malignant arrhythmias. We report the case of two patients who, after having... |
12,459 | Evaluating the impact of implementing an early warning score system on incidence of in-hospital cardiac arrest. | To evaluate the introduction of an early warning score (EWS) system on incidence of in-hospital adult cardiac arrest.</AbstractText>A before-after evaluation of an EWS system (in the form of a patient observation chart with escalation protocol) in a 600 bed tertiary teaching hospital in New Zealand during the two 12-mo... |
12,460 | [Current treatment of tachycardia]. | Tachycardias including atrial fibrillation often require hospitalisation. A diagnostic algorithm from the surface ECG allows discrimination between supraventricular and ventricular tachycardias. For acute treatment, only a few antiarrhythmic drugs such as adenosine, ajmaline and amiodarone, and in case of hemodynamic i... |
12,461 | Is atrial fibrillation always a culprit of stroke in patients with atrial fibrillation plus stroke? | Some ischemic strokes in patients with atrial fibrillation (AF) are caused by noncardioembolic etiologies (AF-unrelated stroke), but not AF itself (AF-related stroke). However, most clinical trials on the risk of stroke in AF have not distinguished between these. We investigated the frequency and features of AF-unrelat... |
12,462 | Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1. | Loss-of-function mutations in Calsequestrin 2 (CASQ2) are associated with catecholaminergic polymorphic ventricular tachycardia (CPVT). CPVT patients also exhibit bradycardia and atrial arrhythmias for which the underlying mechanism remains unknown. We aimed to study the sinoatrial node (SAN) dysfunction due to loss of... |
12,463 | Hypokalemia mimicking a herniated vertebral disc. | A herniated vertebral disc is a common cause of paralysis. Other causes include infections, tumors, and neurologic diseases. A rare and dangerous but in most cases easily treatable cause is hypokalemia. Clinically, the acute symptoms may resemble a herniated vertebral disc, but hypokalemia per se is life-threatening by... |
12,464 | QT Variability Index. | The QT Variability Index (QTVI) is a non-invasive measure of repolarization lability that has been applied to a wide variety of subjects with cardiovascular disease. It is a ratio of normalized QT variability to normalized heart rate variability, and therefore includes an assessment of autonomic nervous system tone. Th... |
12,465 | Ambulatory ECG-based T-wave alternans monitoring for risk assessment and guiding medical therapy: mechanisms and clinical applications. | Identification of individuals at risk for sudden cardiac death (SCD), the main cause of adult mortality in developed countries, remains a major challenge. The main contemporary noninvasive marker, left ventricular ejection fraction (LVEF), has not proved adequately reliable, as the majority of individuals who die sudde... |
12,466 | Prognostic significance of ambulatory ECG monitoring for ventricular arrhythmias. | Ventricular arrhythmia can be detected in ambulatory ECG monitoring in individuals with or without cardiac disease, and its prognostic value varies, depending on the underlying condition. The use of continuous or intermittent ambulatory ECG monitoring can be helpful for diagnosis when there is a high pre-test probabili... |
12,467 | The relationship between paroxysmal atrial fibrillation and coronary artery spasm. | Coronary artery spasm has recently been reported as a complication of the ablation of atrial fibrillation (AF). It may be induced by cardiac autonomic nervous dysfunction during radiofrequency catheter ablation of AF. However, the underlying mechanism is not clear. We hypothesized that patients with paroxysmal AF coinc... |
12,468 | Low serum eicosapentaenoic acid level is a risk for ventricular arrhythmia in patients with acute myocardial infarction: a possible link to J-waves. | Eicosapentaenoic acid (EPA) has antiarrhythmic effects. The J-wave on an electrocardiogram is associated with a high incidence of ventricular tachycardia/fibrillation (VT/VF). We evaluated relationships between EPA and J-waves, and their involvement in the occurrence of VT/VF in acute myocardial infarction (AMI). Two h... |
12,469 | Primary percutaneous coronary intervention for refractory cardiac arrest. | The identification and treatment of reversible causes is paramount to the success of resuscitation in cardiac arrest, particularly when standard therapy has failed. Acute coronary occlusion is one such cause, and the introduction of primary percutaneous coronary intervention services may provide an opportunity for emer... |
12,470 | Burden of arrhythmias in patients with Takotsubo cardiomyopathy (apical ballooning syndrome). | The objective of our study was to assess the burden of arrhythmias, the gender differences in occurrence of arrhythmias and the impact of these arrhythmias on hospitalization outcomes in patients with Takotsubo Cardiomyopathy (TTC).</AbstractText>TTC and various arrhythmias were identified using appropriate ICD-9-CM co... |
12,471 | Dietary omega-3 fatty acids promote arrhythmogenic remodeling of cellular Ca2+ handling in a postinfarction model of sudden cardiac death. | It has been proposed that dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs) can reduce the risk of ventricular arrhythmias in post-MI patients. Abnormal Ca(2+) handling has been implicated in the genesis of post-MI ventricular arrhythmias. Therefore, we tested the hypothesis that dietary n-3 PUFAs alter the vulne... |
12,472 | Defibrillation testing in everyday medical practice during implantable cardioverter defibrillator implantation in France: analysis from the LEADER registry. | Defibrillation testing (DT) is usually performed during implantable cardioverter defibrillator (ICD) implantation.</AbstractText>We conducted a multicentre prospective study to determine the DT procedures used in everyday practice, to compare the characteristics of patients with or without DT, and to compare severe adv... |
12,473 | Early coronary revascularization improves 24h survival and neurological function after ischemic cardiac arrest. A randomized animal study. | Survival after out-of-hospital cardiac arrest (OHCA) remains poor. Acute coronary obstruction is a major cause of OHCA. We hypothesize that early coronary reperfusion will improve 24h-survival and neurological outcomes.</AbstractText>Total occlusion of the mid LAD was induced by balloon inflation in 27 pigs. After 5min... |
12,474 | J waves in accidental hypothermia. | The J wave is an ECG marker of ventricular fibrillation. However, the prevalence and clinical implications of J waves in hypothermic patients remain unclear.</AbstractText>We evaluated the clinical characteristics and ECGs of patients who were admitted for accidental hypothermia (<35.0°C). J waves were defined ... |
12,475 | Characteristics of a large sample of candidates for permanent ventricular pacing included in the Biventricular Pacing for Atrio-ventricular Block to Prevent Cardiac Desynchronization Study (BioPace). | The general clinical profile of European pacemaker recipients who require predominant ventricular pacing (VP) is scarcely known. We examined the demographic and clinical characteristics of the 1808 participants (out of 1833 randomized patients) of the ongoing Biventricular Pacing for Atrio-ventricular Block to Prevent ... |
12,476 | Classic Osborn waves and incessant ventricular fibrillation in severe hypothermia. | Cardiac arrhythmias in severe hypothermia are common and are managed primarily by re-warming techniques. A 64-year-old male presented with alcohol associated aspiration pneumonia, sepsis and severe hypothermia and was noted to have classic ECG changes of hypothermia, i.e. Osborn waves. The patient had a tumultuous clin... |
12,477 | Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog. | Recent evidence points to functional Ca²⁺-dependent K⁺ (SK) channels in the heart that may govern atrial fibrillation (AF) risk, but the underlying mechanisms are unclear. This study addressed the role of SK channels in atrial repolarization and AF persistence in a canine AF model.</AbstractText>Elec... |
12,478 | Characteristics and outcomes of sudden cardiac arrest during sports in women. | No specific data are available on characteristics and outcome of sudden cardiac death (SCD) during sport activities among women in the general population.</AbstractText>From a prospective 5-year national survey, involving 820 subjects 10 to 75 years old who presented with SCD (resuscitated or not) during competitive or... |
12,479 | Antagonistic effects of tetrodotoxin on aconitine-induced cardiac toxicity. | Aconitine, well-known for its high cardiotoxicity, causes severe arrhythmias, such as ventricular tachycardia and ventricular fibrillation, by opening membrane sodium channels. Tetrodotoxin, a membrane sodium-channel blocker, is thought to antagonize aconitine activity. Tetrodotoxin is a potent blocker of the skeletal ... |
12,480 | Directed acyclic graphs helped to identify confounding in the association of disability and electrocardiographic findings: results from the KORA-Age study. | To examine the association between electrocardiographic (ECG) findings and disability status in older adults.</AbstractText>KORA-Age, a population-based cross-sectional study of the MONICA/KORA project, a randomized sample from Southern Germany of people aged 65 years or older.</AbstractText>A total of 534 (51.5%) of 1... |
12,481 | Ventricular arrhythmias: state of the art. | The management of ventricular tachycardia and ventricular fibrillation in the cardiac intensive care unit can be complex. These arrhythmias have many triggers, including ischemia, sympathetic stimulation, and medication toxicities, as well as many different substrates, ranging from ischemic and nonischemic cardiomyopat... |
12,482 | The intersection of atrial fibrillation and heart failure in a hospitalised population. | This work set out to comprehensively characterize patients admitted to hospital with both atrial fibrillation (AF) and heart failure (HF) and to compare this cohort of patients to the global hospital population of patients with only one of these diagnoses.</AbstractText>This was a retrospective analysis of all in-patie... |
12,483 | Ventricular fibrillation-induced cardiac arrest in the rat as a model of global cerebral ischemia. | Cardiopulmonary arrest remains one of the leading causes of death and disability in Western countries. Although ventricular fibrillation (VF) models in rodents mimic the "square wave" type of insult (rapid loss of pulse and pressure) commonly observed in adult humans at the onset of cardiac arrest (CA), they are not po... |
12,484 | Brugada syndrome 1992-2012: 20 years of scientific excitement, and more. | This article describes recent progress on a novel disease that started as a scientific curiosity and has not yet found its end as a scientific revolution. |
12,485 | Kidney protection by hypothermic total liquid ventilation after cardiac arrest in rabbits. | Total liquid ventilation (TLV) with perfluorocarbons has been shown to induce rapid protective cooling in animal models of myocardial ischemia and cardiac arrest, with improved neurological and cardiovascular outcomes after resuscitation. In this study, the authors hypothesized that hypothermic TLV can also limit kidne... |
12,486 | Radial artery catheterization causes pacemaker oversensing in rate-adaptive cardiac pacemakers. | Cardiac catheterization from radial artery access is observed to cause increased heart rate via oversensing in ipsilateral rate adaptive pacemaker. The mechanism of this phenomenon is discussed. This interaction was not observed in the setting of an implanted cardiac defibrillator. |
12,487 | The neuroprotective effect of magnesium sulphate during iatrogenically-induced ventricular fibrillation. | We studied the neuroprotective effect of magnesium sulphate (MgSO4) administered before ventricular fibrillation was induced for internal cardioverter defibrillator threshold testing, and continued during reperfusion.</AbstractText>With the intention of increasing serum magnesium (Mg) to >1.2 mmol/L, 15 patients rec... |
12,488 | The CURE-AF trial: a prospective, multicenter trial of irrigated radiofrequency ablation for the treatment of persistent atrial fibrillation during concomitant cardiac surgery. | Ablation technology has been introduced to replace the surgical incisions of the Cox-Maze procedure in order to simplify the operation. However, the efficacy of these ablation devices has not been prospectively evaluated.</AbstractText>The purpose of this study was to examine the efficacy and safety of irrigated unipol... |
12,489 | Reoperative aortic valve replacement in the octogenarians-minimally invasive technique in the era of transcatheter valve replacement. | Reoperative aortic valve replacement (re-AVR) in octogenarians is considered high risk and therefore might be indicated for transcatheter AVR. The minimally invasive technique for re-AVR limits dissection and might benefit this patient population. We report the outcomes of re-AVR in high-risk octogenarians who might be... |
12,490 | Differential interaction of clinical characteristics with key functional parameters in heart failure with preserved ejection fraction--results of the Aldo-DHF trial. | To investigate the interaction of clinical characteristics with disease characterising parameters in heart failure with preserved ejection fraction (HFpEF). Methods and results In the multicenter, randomized, placebo-controlled, double-blinded, Aldo-DHF trial investigating the effects of spironolactone on exercise capa... |
12,491 | Ventricular fibrillation after bortezomib therapy in a patient with systemic amyloidosis. | A 64-year-old female was diagnosed with systemic amyloidosis associated with multiple myeloma. Bortezomib and dexamethasone-therapy was initiated; however, she developed lethal ventricular fibrillation (VF) and cardiac arrest after 84 hours of therapy. Cardiopulmonary resuscitation using direct current shocks with epin... |
12,492 | Gene expression and genetic variation in human atria. | The human left and right atria have different susceptibilities to develop atrial fibrillation (AF). However, the molecular events related to structural and functional changes that enhance AF susceptibility are still poorly understood.</AbstractText>The purpose of this study was to characterize gene expression and genet... |
12,493 | Course of quantitative ventricular fibrillation waveform measure and outcome following out-of-hospital cardiac arrest. | Quantitative measures of the ventricular fibrillation waveform at the outset of resuscitation are associated with survival. However, little is known about the course of these measures during resuscitation and how this course is related to outcome.</AbstractText>The purpose of this study was to determine how waveform me... |
12,494 | Mutation of KCNJ8 in a patient with Cantú syndrome with unique vascular abnormalities - support for the role of K(ATP) channels in this condition. | KCNJ8 (NM_004982) encodes the pore forming subunit of one of the ATP-sensitive inwardly rectifying potassium (KATP) channels. KCNJ8 sequence variations are traditionally associated with J-wave syndromes, involving ventricular fibrillation and sudden cardiac death. Recently, the KATP gene ABCC9 (SUR2, NM_020297) has bee... |
12,495 | New-onset atrial fibrillation predicts malignant arrhythmias in post-myocardial infarction patients--a Cardiac Arrhythmias and RIsk Stratification after acute Myocardial infarction (CARISMA) substudy. | After myocardial infarction (MI) the risk of sudden cardiac death due to arrhythmias is substantial.</AbstractText>The purpose of this study was to investigate if new-onset atrial fibrillation (AF) is associated with development of potential malignant brady- and tachyarrhythmias after an acute MI.</AbstractText>The stu... |
12,496 | Predicting early left ventricular dysfunction after mitral valve reconstruction: the effect of atrial fibrillation and pulmonary hypertension. | The preoperative ejection fraction (EF) and left ventricular (LV) end-systolic dimension are known predictors of postoperative LV dysfunction after mitral valve repair. We investigated the effect of a preoperative history of atrial fibrillation and moderate pulmonary hypertension (defined as pulmonary artery systolic p... |
12,497 | Low Voltage Electric Injury induced Atrial Fibrillation as a Presenting Feature of Wolff-Parkinson-White Syndrome: A Case Report. | Electric injury can cause a variety of cardiac arrhythmias. Atrial fibrillation as a result of such injury is very rare. We present a case of a young asymptomatic patient who developed acute atrial fibrillation with antegrade conduction over the atrioventricular bypass tract and very high ventricular rate after acciden... |
12,498 | Catheter Ablation of Polymorphic Ventricular Tachycardia and Ventricular Fibrillation. | Recently, catheter ablation (CA) has become a therapeutic option to target focal triggers of polymorphic ventricular tachycardia and ventricular fibrillation (VF) in the setting of electrical storm (ES). This strategy was first described in subjects without organic heart disease (i.e. idiopathic VF) and subsequently in... |
12,499 | What About Tachycardia-induced Cardiomyopathy? | Long-standing tachycardia is a well-recognised cause of heart failure and left ventricular dysfunction, and has led to the nomenclature, tachycardia-induced cardiomyopathy (TIC). TIC is generally a reversible cardiomyopathy if the causative tachycardia can be treated effectively, either with medications, surgery or cat... |
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