Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
2,322,300 | Colloid-like cyst located in the prepontine region. | The term "colloid cysts" refers to nonneoplastic lesions located in the anterior part of the third ventricle. However, cysts morphologically identical to colloid cysts are found, albeit extremely rarely, through the neuraxis.</AbstractText>We report a case of a 44-year-old man with a short history of headache and 5 yea... |
2,322,301 | Intrinsic third ventricular craniopharyngiomas: report on six cases and a review of the literature. | Craniopharyngiomas constitute 2 to 4% of intracranial neoplasms. However, the purely intraventricular variety are rare. Their magnetic resonance imaging (MRI) characteristically shows an intact third ventricular floor, a patent suprasellar cistern, an intact pituitary stalk, and the absence of sellar abnormalities.</Ab... |
2,322,302 | Macrophages and dendritic cells in the rat meninges and choroid plexus: three-dimensional localisation by environmental scanning electron microscopy and confocal microscopy. | The present investigation provides novel information on the topographical distribution of macrophages and dendritic cells (DCs) in normal meninges and choroid plexus of the rat central nervous system (CNS). Whole-mounts of meninges and choroid plexus of Lewis rats were incubated with various anti-leucocyte monoclonal a... |
2,322,303 | The Chiari II malformation: cause and impact. | It is the Chiari II malformation and its effects that determine the quality of life of the individual born with spina bifida.</AbstractText>The cause of this malformation has been a source of debate for many years. Understanding the cause enables strategies for the management of problems created by this malformation to... |
2,322,304 | Altered expression of angiopoietins during blood-brain barrier breakdown and angiogenesis. | Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) belong to a novel family of endothelial growth factors that function as ligands for the endothelial-specific receptor tyrosine kinase, Tie-2. Ang-1 reduces endothelial permeability of noncerebral vessels and has a major role in vascular stabilization and maturation, whe... |
2,322,305 | Gene transfer of IkappaBalpha limits infarct size in a mouse model of myocardial ischemia-reperfusion injury. | Nuclear factor-kappaB (NF-kappaB) plays a central role in myocardial ischemia-reperfusion (MI/R) injury. The inhibitory protein IkappaBalpha prevents its activation. We investigated the effects of adeno-associated viral vector-mediated IkappaBalpha gene transfer in MI/R injury. Male C57BL/6 mice were randomized to rece... |
2,322,306 | Impact of blood pressure and insulin on the relationship between body fat and left ventricular structure. | Obesity leads to hypertension and metabolic disturbances, as well as left ventricular hypertrophy and altered left ventricular geometry. However, the underlying mechanisms behind these relationships are not clear. The aim of this study was to investigate how body composition, blood pressure and metabolic factors relate... |
2,322,307 | Capturing in situ skeletal muscle power for circulatory support: a new approach to device design. | Efforts to harness in situ skeletal muscle for circulatory support have been extensive, but implants designed to tap this power source have yet to meet the strict performance standards incumbent upon such devices. A fourth generation muscle energy converter (MEC4) is described that represents a significant departure fr... |
2,322,308 | [Effect of acute hypoxic hypoxia on nitric oxide synthase induction in rats].<Pagination><StartPage>47</StartPage><EndPage>49</EndPage><MedlinePgn>47-9</MedlinePgn></Pagination><Abstract><AbstractText>Male Wistar rats were exposed to acute normobaric hypoxia (10% O2) during 1 or 3 h. After 24 h iNOS protein expression ... | Male Wistar rats were exposed to acute normobaric hypoxia (10% O2) during 1 or 3 h. After 24 h iNOS protein expression was estimated in tissues by Western blotting. It was found, that iNOS protein expression was higher in heart right ventricles versus left ventricles in both control (intact) and hypoxic animals. Hypoxi... |
2,322,309 | In vivo pyruvate detected by MR spectroscopy in neonatal pyruvate dehydrogenase deficiency. | We present a unique finding of an elevated level of pyruvate at 2.37 ppm revealed by in vivo MR spectroscopy of a female neonate. Low fibroblast pyruvate dehydrogenase (PDH) complex activity subsequently confirmed a diagnosis of PDH deficiency. Abnormalities of brain development consistent with PDH deficiency were also... |
2,322,310 | Expanding Virchow Robin spaces in the midbrain causing hydrocephalus. | We describe a patient who showed cystic lesions in the midbrain and obstructive hydrocephalus. MR imaging features corresponded to abnormal dilatation of perivascular spaces. Similar clinical and MR imaging findings were described in previous reports of patients presenting with mesencephalo-thalamic expanding lacunae; ... |
2,322,311 | Imaging features of sellar cysticercosis. | Cases of sellar involvement of neurocysticercosis (NCC) are rare. Little is known about the mechanisms by which the parasite can compromise the pituitary gland. Although NCC damages sellar structures with direct compression by large cysts, extension through the basal cisterns and third ventricle with focal arachnoiditi... |
2,322,312 | [Ventriculomegaly without dysraphic malformations--retrospective analysis fetuses diagnosed in the Department of Gynecology & Obstetrics of the Postgraduate Center of Medical Education in Warsaw, between 1997-2002]. | Our objective was to determine if ventriculomegaly not related to the open neural tube defects is associated with other anomalies and aneuploidy. What we should do after such diagnosis. We also analyzed gestational age at the first examination.</AbstractText>We retrospectively studied ultrasound reports of the fetuses ... |
2,322,313 | Rosette-forming glioneuronal tumor of the fourth ventricle. | Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle has been reported recently as a novel type of primary CNS neoplasm. We present the case of a 35-year-old male patient with RGNT of the fourth ventricle. The tumor was found incidentally; the patient did not suffer from any neurological symptoms. The tumo... |
2,322,314 | Adenosine A1 and A2A receptor cross-talk during ageing in the rat myocardium. | Adenosine (Ado), a naturally occurring autacoid, exerts cardioprotective effects against myocardial ischemia and reperfusion injury, through activation of its receptors type 1 (A1) and 2A (A2A). Since ageing involves a complex change in these effects, we evaluated A1 and A2A gene expression in left (LV) and right ventr... |
2,322,315 | A single and novel natriuretic peptide is expressed in the heart and brain of the most primitive vertebrate, the hagfish (Eptatretus burgeri). | In teleost fish and tetrapods, the natriuretic peptide (NP) family consists of ANP (atrial natriuretic peptide), BNP (brain natriuretic peptide) and VNP (ventricular natriuretic peptide) that are secreted from the heart, and C-type natriuretic peptide (CNP) that is found in the brain. However, CNP is the only NP identi... |
2,322,316 | A double dissociation between serial reaction time and radial maze performance in rats subjected to 192 IgG-saporin lesions of the nucleus basalis and/or the septal region. | The cholinergic basal forebrain has been implicated in aspects of cognitive function including memory and attention, but the precise contribution of its major components, the basalocortical and the septohippocampal systems, remains unclear. Rats were subjected to lesions of either the nucleus basalis magnocellularis (B... |
2,322,317 | Bobble-head doll syndrome: some atypical features with a new lesion and review of the literature. | Bobble-head doll syndrome is a rare and unique movement disorder encountered in children. It is characterized by continuous or episodic involuntary forward and backward and side to side movement of the head at the frequency of 2-3 Hz. Neuroimaging in most of the cases reveals third ventricular tumors, suprasellar arach... |
2,322,318 | Effects of iNOS-related NO on hearts exposed to liposoluble iron. | Inducible nitric oxide synthase (iNOS) protects heart against ischemia/reperfusion injury. However, it is unknown whether the beneficial effects of iNOS are mediated by the interaction of NO with radical oxygen species (ROS). To address this issue, we examined the effects of liposoluble iron-induced ROS generation in i... |
2,322,319 | Determination of lesion size by ultrasound during radiofrequency catheter ablation. | The catheter tip temperature that is used to control the radiofrequency generator output poorly correlates to lesion size. We, therefore, evaluated lesions created in vitro using a B-mode ultrasound imaging device as a potential means to assess lesion generation during RF applications non-invasively. Porcine ventricula... |
2,322,320 | [Neuro-endoscopic techniques in the treatment of complex hydrocephalus in children]. | The aim of the paper was to evaluate effectiveness of neuroendoscopic procedures in comparison to complex shunt systems implantation in the treatment of complex compartmentalized hydrocephalus in children. Neuroendoscopic techniques were applied in 47 patients (23 boys, 24 girls aged from 25 days to 18 years, mean age ... |
2,322,321 | Neurogenesis and glial proliferation persist for at least one year in the subventricular zone following brain trauma in rats. | In several models of traumatic brain injury in rodents, remarkably progressive tissue loss and neuron death has been observed accompanied by expanding ventricles. Here, we explored potential cell proliferation in the subventricular zone (SVZ) in response to this progressive posttraumatic neurodegeneration. Four-month-o... |
2,322,322 | Acquired aqueductal stenosis in preterm infants: an indication for neuroendoscopic third ventriculostomy. | The object of this study is to demonstrate the delayed occurrence of aqueductal stenosis in preterm infants who have suffered from intraventricular hemorrhage (IVH) and to try to explain the mechanisms of this stenosis.</AbstractText>From January 1996 to June 2002, 1,046 premature infants were admitted to our instituti... |
2,322,323 | In vivo quantitative ultrasonic evaluation of neonatal brain with a real time integrated backscatter imaging system. | We applied the integrated backscatter (IBS) imaging system to the evaluation of the normal neonatal brain of different birth-weights: extremely low-birth-weight (N=13), very-low-birth-weight (N=14), low-birth weight (N=14), and normal birth weight (N=19). The IBS values in six regions of interest, the deep white matter... |
2,322,324 | Right ventricular involvement in myocardial infarction and cardiogenic shock. | Right ventricular involvement in acute myocardial infarction and cardiogenic shock has received little attention by clinicians and researchers, although its pathophysiology, clinical presentation, and natural history are distinctly different from those of left ventricular infarction and associated cardiogenic shock. Ri... |
2,322,325 | Relationship of contractile function to transmural extent of infarction in patients with chronic coronary artery disease. | We sought to determine the relationship of contractile function to the transmural extent of infarction (TEI) in patients with chronic coronary artery disease.</AbstractText>In the setting of reperfused, chronic myocardial infarction (MI), the relationship of contractile function to the TEI has not been established.</Ab... |
2,322,326 | An alternative method of chronic cerebrospinal fluid collection via the cisterna magna in conscious rhesus monkeys. | Models of chronic cerebrospinal fluid (CSF) collection previously have been established for nonhuman primates and canines; many of these methods implement stainless-steel cannulas into the lateral or 4th ventricles or catheters into the cerebral or spinal subarachnoid space. These models have proved successful and reli... |
2,322,327 | [Experimental study of cardiac muscle tissue engineering in bioreactor]. | This study investigates construction of cardiac muscle cell-porous collagen scaffold complex in a bioreactor so as to unveil the possibility of generating 3-dimensional cardiac muscle tissue under the environment that mimics microgravity in vitro.</AbstractText>1-2-day old neonatal rat cardiac muscle cells were isolate... |
2,322,328 | Outcome of antenatally diagnosed intracranial hemorrhage: case series and review of the literature. | Prenatal diagnosis of intracranial hemorrhage (ICH) has been widely reported. Hemorrhages may occur either within the cerebral ventricles, subdural space or infratentorial fossa. The aim of this study was to determine the sonographic criteria for the diagnosis of fetal ICH, the role of in utero magnetic resonance imagi... |
2,322,329 | Ventriculostomy in a tumor involving the third ventricular floor. | Recently, endoscopic management has gotten preference over open surgical treatment in selected cases of intraventricular tumors. Endoscopic third ventriculostomy (ETV) appears unfeasible when tumors extend to the third ventricular floor region due to the risk of perforators and injury to the basilar artery. We report t... |
2,322,330 | Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats. | Agomelatine, an antidepressant with melatonin agonist and 5-HT(2C) antagonist properties, as well as two of its main metabolites, S 21517 (N-[2-(7-hydroxy-1-naphtyl)ethyl]acetamide) and S21540 (N-[2-(3-hydroxy-7-methoxynaphtalen-1-yl)ethyl]acetamide), have been assessed in vitro on pig choroid plexus preparations to de... |
2,322,331 | A broad role for melanopsin in nonvisual photoreception. | The rod and cone photoreceptors that mediate visual phototransduction in mammals are not required for light-induced circadian entrainment, negative masking of locomotor activity, suppression of pineal melatonin, or the pupillary light reflex. The photopigment melanopsin has recently been identified in intrinsically pho... |
2,322,332 | Blockade of GABA(B) receptors alters the tangential migration of cortical neurons. | To better understand the role of neurotransmitter receptors in neuronal differentiation and maturation a detailed knowledge of their identity, location and function in the plasma membrane of specific neuronal populations during development is required. Combining pre-embedding immunocytochemistry with cell tracking in e... |
2,322,333 | Primary progressive multiple sclerosis: a 5-year clinical and MR study. | Longitudinal imaging studies of primary progressive multiple sclerosis (PPMS) have shown significant changes in MR measures over 1 to 2 years. Correlation with clinical change over the same period has not been evident; we investigated the possibility that this is because the period of observation was insufficient for t... |
2,322,334 | The sensory circumventricular organs of the mammalian brain. | The brain's three sensory circumventricular organs, the subfornical organ, organum vasculosum of the lamina terminalis and the area postrema lack a blood brain barrier and are the only regions in the brain in which neurons are exposed to the chemical environment of the systemic circulation. Therefore they are ideally p... |
2,322,335 | Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain. | Recombinant adeno-associated virus serotype 2 (rAAV2) vectors have shown promise as therapeutic agents for neurologic disorders. However, intracerebral administration of this vector leads to preferential transduction of neurons and a restricted region of transgene expression. The recently developed rAAV vectors based u... |
2,322,336 | Preconditioning by hypoventilation increases ventricular arrhythmia threshold in Wistar rats. | Hypoventilation, as one of ventilatory disorders, decreases the electrical stability of the heart similarly as ischemia. If preconditioning by short cycles of ischemia has a cardioprotective effect against harmful influences of a prolonged ischemic period, then preconditioning by hypoventilation (HPC) can also have a s... |
2,322,337 | Effects of the HOE 694 on transient inward current and Na(+) - Ca(2+) exchange in guinea pig cardiomyocytes. | To determine the effects of HOE 694, a new and potent Na(+)-H+ exchanger blocker, on transient inward current (It(i)) and Na(+) - Ca(2+) exchange during hypoxia-reoxygenation in guinea pig cardiomyocytes. METHODS. Cardiomyocytes were isolated from adult guinea pig ventricle. Experiment was performed in an experimental ... |
2,322,338 | Differential patterns of glial fibrillary acidic protein-immunolabeling in the brain of adult lizards. | The present study describes by means of immunohistochemistry the comparative distribution of glial fibrillary acidic protein (GFAP)-positive cells in the forebrain and midbrain of three species of lizards: Eumeces algeriensis, Scincoidae; Agama impalearis, Agamidae; Tarentola mauritanica, Gekkonidae. In the species stu... |
2,322,339 | Stress protein expression in the Alzheimer-diseased choroid plexus. | Abnormal patterns of stress protein expression are found in the cerebral cortex and hippocampus of Alzheimer (AD) subjects. In this study, expression of various stress proteins in the Alzheimer-diseased choroid plexus (CP) was assessed immunohistochemically. We observed decreased HO-1 immunoreactivity in the AD CP, com... |
2,322,340 | Analysing differences in clinical outcomes between hospitals. | To examine the variation between hospitals in rates of severe intraventricular haemorrhage (IVH) in preterm babies adjusting for case mix and sampling variability.</AbstractText>Cross sectional study of pooled data from 1995 to 1997.</AbstractText>24 neonatal intensive care units (NICUs) in the Australian and New Zeala... |
2,322,341 | Neural trans-differentiation potential of hepatic oval cells in the neonatal mouse brain. | Although the existence of the hepatic oval cell (HOC), the liver stem cell has been known for almost 70 years, little is known about the potential for this adult stem cell to trans-differentiate into cells of other tissues. While their origin remains enigmatic, HOCs share many similarities with hematopoietic stem cells... |
2,322,342 | Experience of cranial ultrasonography in admitted symptomatic neonates. | In infants who have experienced perinatal injury or who have neurological symptoms, it is often difficult on the basis of history and clinical examination to come to a proper diagnosis. Cranial ultrasonography of the symptomatic neonates can often diagnose the underlying pathology. Cranial ultrasonography of 28 admitte... |
2,322,343 | Coupling of cardiac electrical activity over extended distances by fibroblasts of cardiac origin. | Roughly half of the cells of the heart consist of nonmyocardial cells, with fibroblasts representing the predominant cell type. It is well established that individual cardiomyocytes and fibroblasts in culture establish gap junctional communication at the single cell level (short-range interaction). However, it is not k... |
2,322,344 | Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis. | We have identified a novel form of cardiac myocyte enlargement in nonmuscle myosin heavy chain II-B (NMHC II-B) ablated mice, based on a partial failure in cytokinesis. In contrast to most cells, cardiac myocytes lack NMHC II-A, and ablation of NMHC II-B results in a heart with 70% fewer myocytes at embryonic day 14.5 ... |
2,322,345 | The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes. | One of the major manifestations of obesity is increased production of the adipocyte-derived 16-kDa peptide leptin, which is also elevated in heart disease, including congestive heart failure. However, whether leptin can directly alter the cardiac phenotype is not known. We therefore studied the effect of leptin as a po... |
2,322,346 | Brain volume, asymmetry and intellectual impairment in relation to sex in early-onset schizophrenia. | Accumulating evidence suggests that early-onset schizophrenia arises from a disturbance in the normal trajectory of cerebral development.</AbstractText>To investigate brain structure, asymmetry and IQ in early-onset schizophrenia.</AbstractText>Volumes of left and right cerebral hemispheres and IQ were assessed in 33 p... |
2,322,347 | Myocardial kinematics from tagged MRI based on a 4-D B-spline model. | Current research investigating the modeling of left ventricular dynamics for accurate clinical assessment of cardiac function is extensive. Magnetic resonance (MR) tagging is a functional imaging method which allows for encoding of a grid of signal voids on cardiac MR images, providing a mechanism for noninvasive measu... |
2,322,348 | Quantitative clinical assessment of chronic anterior myocardial infarction with delayed enhancement magnetic resonance imaging and QRS scoring. | Both the regional and global myocardial extent of chronic myocardial infarction (MI) are important prognostic factors for length and quality of life and also crucial for the choice of therapy in patients with ischemic heart disease. Our aim was to develop and validate techniques for comparison between regional and glob... |
2,322,349 | Pharmacological evidence for involvement of phospholipase D, protein kinase C, and sodium-calcium exchanger in alpha-adrenoceptor-mediated negative inotropy in adult mouse ventricle. | The intracellular signalling pathway for alpha-adrenoceptor-mediated negative inotropy was studied pharmacologically in isolated adult mouse ventricle. The negative inotropy was inhibited by GF-109203X, a nonselective protein kinase C inhibitor. Phorbol 12-myristate 13-acetate also produced sustained negative inotropy,... |
2,322,350 | Malondialdehyde inhibits cardiac contractile function in ventricular myocytes via a p38 mitogen-activated protein kinase-dependent mechanism. | (1) Increased oxidative stress plays a significant role in the etiology of cardiovascular disease. Lipid peroxidation, initiated in the presence of hydroxy radicals resulting in the production of malondialdehyde, directly produces oxidative stress. This study was designed to examine the direct impact of malondialdehyde... |
2,322,351 | Premorbid intellectual functioning, education, and brain size in traumatic brain injury: an investigation of the cognitive reserve hypothesis. | Cognitive reserve theories have been postulated in an attempt to explain individual differences in functional outcome following cerebral insult or disease. These theories suggest that higher education and psychometric intelligence may preserve functional capacity regardless of injury or disease severity. This study inv... |
2,322,352 | Organization of projections from the raphe nuclei to the vestibular nuclei in rats. | Previous anatomic and electrophysiological evidence suggests that serotonin modulates processing in the vestibular nuclei. This study examined the organization of projections from serotonergic raphe nuclei to the vestibular nuclei in rats. The distribution of serotonergic axons in the vestibular nuclei was visualized i... |
2,322,353 | Cardiac energetics: from E(max) to pressure-volume area. | 1. To celebrate this Festschrift for Professor Colin Gibbs, as an invited speaker, I would like to review briefly my 35 year research career in cardiac physiology. 2. My career started in the late 1960s in Tokyo with my serendipitous discovery of Emax (ventricular end-systolic maximum elastance) as a load-independent c... |
2,322,354 | Increased cardiac weight in interleukin-6 transgenic mice with viral infection accompanies impaired expression of natriuretic peptide genes.<Pagination><StartPage>275</StartPage><EndPage>283</EndPage><MedlinePgn>275-83</MedlinePgn></Pagination><Abstract><AbstractText>Atrial natriuretic peptide (ANP) and B-type natriure... | Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) regulate cardiac hypertrophy. We investigated ventricular alterations of ANP and BNP in interleukin-6 (IL-6) transgenic mice (TG) and wild type (WT) mice with or without viral infection. The ANP and BNP mRNA/GAPDH mRNA ratios in the ventricles of IL-... |
2,322,355 | [Effects of stress on L type calcium channels of rat ventricular myocytes]. | To observe the effects of stress on Ica-L, steady-state activation curves and steady-state inactivation curves.</AbstractText>Use NE to construct stress cell model, then the whole-cell patch-clamp recording technique was used to record the Ica-L, the steady-state activation curves and the steady-state inactivation curv... |
2,322,356 | Cardiac MIBG scintigraphy is a sensitive tool for detecting cardiac sympathetic denervation in Parkinson's disease. | [(123)I]Metaiodobenzylguanidine ([(123)I]MIBG) cardiac scintigraphy could be helpful to differentiate Parkinson's disease (PD) from multiple system atrophy (MSA), demonstrating that, in PD with autonomic failure but not in MSA, there is a myocardial postganglionic sympathetic dysfunction. To investigate whether this me... |
2,322,357 | Three dimensional modeling of the cerebrospinal fluid dynamics and brain interactions in the aqueduct of sylvius. | A computational fluid dynamics (CFD) method is presented to investigate the flow of cerebro-spinal fluid (CSF) in the cerebral aqueduct. In addition to former approaches exhibiting a rigid geometry, we propose a model which includes a deformable membrane as the wall of this flow channel. An anatomical shape of the aque... |
2,322,358 | Moderate alcohol exposure compromises neural tube midline development in prenatal brain. | We previously reported that fetal alcohol treatment compromised the development of the midline raphe and the serotonin neurons contained in it. In this study, we report that the timely development of midline neural tissue during neural tube formation is sensitive to alcohol exposure. Pregnant dams were treated from emb... |
2,322,359 | Comparison of left ventricular function by echocardiogram in patients with Wilms' tumor treated with anthracyclines versus those not so treated. | The aim of this report was to evaluate late left ventricular function in survivors of Wilms' tumor and to compare patients treated with anthracyclines with those treated without anthracycline and with normal subjects. Wilms' tumor survivors treated without anthracycline had no myocardial abnormalities. A large percenta... |
2,322,360 | Left ventricular free wall rupture after reperfusion therapy for acute myocardial infarction. | We evaluated the clinical significance of angiographic indexes and pericardial involvement in predicting increased risk of free wall rupture after reperfusion therapy and found that Thrombolysis In Myocardial Infarction (TIMI) <3 flow grade after reperfusion therapy was a significant variable related to the free wal... |
2,322,361 | Effect of i.c.v. infusion of the alpha-MSH agonist MTII on meal patterns in male rats following nicotine withdrawal. | The present study explored the role of endogenous alpha-MSH in the alteration of meal patterns induced by nicotine (NIC) withdrawal. Male Sprague Dawley rats bearing third ventricle cannulas were placed in computerized food intake monitors. On days 1-21, the rats were given 4 mg/kg/day of NIC or saline (SAL) in four eq... |
2,322,362 | CREB is required for acquisition of ischemic tolerance in gerbil hippocampal CA1 region. | Ischemic tolerance is well known as a neuroprotective effect of pre-conditioning ischemia against delayed neuronal death, however, the mechanism or mechanisms underlying this effect are not fully understood. We investigated the relationship between CREB and ischemic tolerance in gerbil hippocampal CA1 neurons using CRE... |
2,322,363 | Effects of inter- and intra-observer variability on echocardiographic measurements in awake cats. | The objective of this study was to determine intra- and inter-observer variability of echocardiographic measurements in awake cats. Four observers with different levels of experience in echocardiography performed 96 echocardiographic examinations in four cats on four different days over a 3-week period. The examination... |
2,322,364 | Identification of circadian brain photoreceptors mediating photic entrainment of behavioural rhythms in lizards. | We have shown previously that in ruin lizards (Podarcis sicula) the ablation of all known photoreceptive structures (lateral eyes, pineal and parietal eye) in the same individual animal does not prevent entrainment of their circadian locomotor rhythms to light. The present study was aimed at identifying the circadian b... |
2,322,365 | Insulin-like growth factor II mRNA is expressed in neurones of the brain of the bony fish Oreochromis mossambicus, the tilapia. | The physiological meaning of insulin-like growth factor II (IGF-II) is still enigmatic. IGF-II occurs in the adult mammalian brain where it is expressed in the mesodermal portion of the choroid plexus and the meninges, but results on its presence in cells of neuroepithelial origin are controversial. However, IGF-II mRN... |
2,322,366 | Choroidal bodies: a new structure in the fourth ventricular choroid plexus of the rat and mouse. | Histologic study of the caudal end of the fourth ventricular choroid plexus of the rat and mouse revealed 1-4 small, discrete collections of cells that differed from the surrounding choroidal epithelial cells in appearance. They did not occur in other parts of the choroid plexuses. These choroidal bodies were not affec... |
2,322,367 | Central 5-HT2B/2C and 5-HT3 receptor stimulation decreases salt intake in sodium-depleted rats. | In the present study, we investigated the participation of central 5-HT(2B/2C) and 5-HT(3) receptors in the salt intake induced by sodium depletion in Wistar male rats. Sodium depletion was produced by the administration of furosemide associated with a low salt diet. Third ventricle injections of mCPP, a 5-HT(2B/2C) ag... |
2,322,368 | Eurasian otter (Lutra lutra), a definitive host for Dirofilaria immitis. | A mature male and a mature female Dirofilaria immitis were found in the right ventricle of the heart of a naturally infected 2-yr-old male Eurasian otter (Lutra lutra) that had died of severe lung congestion at a zoo in South Korea. Both developing embryos and microfilariae were present in the uterus of the female D. i... |
2,322,369 | Expression of transgenes in primary neurons from chick peripheral and central nervous systems by retroviral infection of early embryos. | Many cell biological studies require the expression of transgenes in cells in culture, but it is difficult to obtain uniform, stable, and efficient expression of transgenes in primary neurons. We have approached this problem by adapting from developmental biologists the avian retroviral vector, RCAS. This vector allows... |
2,322,370 | Improvement in the quantification of myocardial perfusion using an automatic spline-based registration algorithm. | To improve the quantification of myocardial perfusion by registering the time series of magnetic resonance (MR) images with injection of gadolinium.</AbstractText>Eight patients underwent MR scans to perform myocardial perfusion exam. Two short axis views of the left ventricle (LV) were acquired in free breathing. Two ... |
2,322,371 | Selective modulation of endogenous nitric oxide formation in ischemia/reperfusion injury in isolated rat hearts--effects on regional myocardial flow and enzyme release. | The role of nitric oxide (NO) in ischemia/reperfusion injury is controversial. We tested the role of inducible NOS (iNOS) in the ischemia/reperfusion injury in isolated rat hearts using the selective iNOS inhibitor S-methylisothiourea sulfate (SMT) and the non-selective NOS inhibitor N(G)-nitro-L-arginine methyl ester ... |
2,322,372 | Prenatal assessment of ventriculomegaly: an anatomical study. | The aim of the study was to analyze the development of the lateral ventricles during the 1st and 2nd trimester of fetal life using computerized image processing, and to compare the findings with the results obtained by ultrasound imaging and MRI.</AbstractText><AbstractText Label="MATERIAL/METHODS" NlmCategory="METHODS... |
2,322,373 | Ketorolac attenuates cardiopulmonary derangements in sheep with combined burn and smoke inhalation injury. | Massive cutaneous burn combined with smoke inhalation causes high mortality in fire victims. Cyclo-oxygenase (COX) and inducible nitric oxide (NO) synthase (iNOS) have been shown to be up-regulated in burn injury. Ketorolac, a non-steroidal, anti-inflammatory agent (NSAID), inhibits prostaglandin and thromboxane synthe... |
2,322,374 | Influence of changes in glutathione concentration on body temperature and tolerance to cerebral ischemia. | Two compounds that deplete glutathione (buthionine sulfoximine and diethyl maleate) with different mechanisms of action decrease body temperature and increase tolerance to complete global cerebral ischemia, both correlating closely with the glutathione concentration decrease. Glutathione apparently participates in the ... |
2,322,375 | Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice. | Neurogenesis, which may contribute to the ability of the adult brain to function normally and adapt to disease, nevertheless declines with advancing age. Adult neurogenesis can be enhanced by administration of growth factors, but whether the aged brain remains responsive to these factors is unknown. We compared the eff... |
2,322,376 | Cardiac pseudotumor: tissue characterization by cardiovascular magnetic resonance. | We present serial cardiovascular magnetic resonance (CMR) in a case of cardiac pseudotumor (inflammatory myofibroblastic tumor). The diagnosis proved difficult and was helped by myocardial tissue characterization using CMR. Intrinsic contrast and extrinsic contrast (using gadolinium-DTPA perfusion, early and late imagi... |
2,322,377 | Cannabinoid1 receptor in the dorsal vagal complex modulates lower oesophageal sphincter relaxation in ferrets. | Delta9-tetrahydrocannabinol (delta9-THC) is an effective anti-emetic; however, other potential gastrointestinal therapeutic effects of delta9-THC are less well-known. Here, we report a role of delta9-THC in a vago-vagal reflex that can result in gastro-oesophageal reflux, that is, gastric distension-evoked lower oesoph... |
2,322,378 | Ventricular dilatations. | Ventricular dilatation is generally defined on ultrasounds (US) or MRI as an atrium larger than 10 to 12 mm on axial or coronal planes. After 22 weeks, this measure is independent of the term.</AbstractText>In the view of the prognostication, it is of utmost importance to not only calculate the width of the ventricles ... |
2,322,379 | Dandy-Walker malformation: prenatal diagnosis and prognosis. | The difficulty in prognosticating the clinical and intellectual outcome of fetuses presenting with a Dandy-Walker malformation (DWM) comes from the great variety of cystic, median, and retrocerebellar malformations that probably have nothing in common and the variability of the definitions given to these lesions. In ad... |
2,322,380 | Determination of indices of the corpus callosum associated with normal aging in Japanese individuals. | Indices of the corpus callosum with normal aging and their sex differences were elucidated using quantitative MRI. We studied 94 Japanese men (mean+/-SD 57.3+/-20.8 years, range 6-90 years) and 111 Japanese women (mean+/-SD 61.2+/-17.6 years, range 9-86 years) who had no intracranial lesions on MRI and no history of ne... |
2,322,381 | Postnatal increase in insulin-sensitive glucose transporter expression is associated with improved recovery of postischemic myocardial function. | Glucose is an important substrate for energy production in the developing heart. Increased glucose uptake rate and metabolism during ischemia and reperfusion are closely linked to postischemic myocardial recovery. The initial rate-limiting step for glycolysis is the transport of glucose across the plasma membrane by gl... |
2,322,382 | Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs): in vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation. | The nitric oxide (NO)-cGMP pathway has been implicated as playing a crucial role in the induction of cerebellar long-term depression (LTD). The amplitude and duration of the cGMP signal is controlled by cyclic nucleotide phosphodiesterases (PDEs). Here we identify PDE5 and PDE1B as the two major cGMP-hydrolyzing PDEs s... |
2,322,383 | Environment temperature affects cell proliferation in the spinal cord and brain of juvenile turtles. | The spinal cords and brains--comprising dorsal cortex (DC), medial cortex (MC) and diencephalon (Dien)--of juvenile turtles acclimated to warm temperature [27-30 degrees C; warm-acclimated turtles (WATs)] revealed higher density values of bromodeoxyuridine-labeled cells (BrdU-LCs) than those acclimated to a cooler envi... |
2,322,384 | Myocardial laser coagulation for free wall rupture following acute infarction. | A 73-year-old woman was diagnosed with ventricular free wall rupture following acute myocardial infarction. The lesion was repaired with laser coagulation, fibrinogen-thrombin glue application, and patch reinforcement. Five years after surgery, the patient was in New York Heart Association class I. |
2,322,385 | Opposing effects of delta- and zeta-protein kinase C isozymes on cardiac fibroblast proliferation: use of isozyme-selective inhibitors. | Neonatal primary cardiac fibroblasts in defined medium continue to proliferate. Here, we show that phorbol ester inhibited and transforming growth factor-beta1 (TGFbeta1) stimulated this fibroblast proliferation. Cardiac fibroblasts contain six protein kinase C (PKC) isozymes: alpha-, delta-, epsilon-, betaI-, betaII-,... |
2,322,386 | Expression of leukotriene C4 synthase mRNA by the choroid plexus in mouse brain suggests novel neurohormone functions of cysteinyl leukotrienes. | Leukotriene C(4) is a potent mediator of allergic and inflammatory reactions, and is formed from arachidonic acid and glutathione through the sequential action of 5-lipoxygenase and leukotriene C(4) synthase (LTCS). These enzymes are predominantly expressed in cells of myeloid lineage. In this report, we have investiga... |
2,322,387 | Cerebroventricular administration of interferon-gamma modifies locomotor activity in the golden hamster. | The present study was undertaken to examine whether the intracerebroventricular (i.c.v.) administration of interferon (IFN)-gamma could modify 24-hour wheel running locomotor activity in the golden hamster. Hamsters implanted with a cannula in the third ventricle received a single i.c.v. injection of 1 microl of murine... |
2,322,388 | Myocardial protective effect of hypothermia during extracorporeal circulation -- by quantitative measurement of myocardial oxygen consumption -. | To evaluate the effect of systemic temperature on myocardial protection during extracorporeal circulation, we quantitatively evaluated the relationship between myocardial oxygen consumption and rectal temperature.</AbstractText>Myocardial oxygen consumption during cardiac arrest was calculated via blood gas analysis of... |
2,322,389 | Phased-array intracardiac echocardiography for defining cavotricuspid isthmus anatomy during radiofrequency ablation of typical atrial flutter.<Pagination><StartPage>591</StartPage><EndPage>597</EndPage><MedlinePgn>591-7</MedlinePgn></Pagination><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Cavo... | Ischaemic preconditioning (IP) is a strong endogenous infarct reducing stimulus which has not previously been evaluated with myocardial perfusion imaging using 99mTc-MIBI. Factors responsible for cellular MIBI uptake are affected by both IP and acute ischaemia (plasma membrane and mitochondrial membrane potential and o... |
2,322,390 | A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging. | To investigate the effect of age on global and regional brain volumes and rates of atrophy, and to compare directly results based on cross-sectional and longitudinal data.</AbstractText>Thirty-nine healthy control subjects (age range, 31-84 years) underwent serial magnetic resonance imaging assessments. Measurements in... |
2,322,391 | A level set approach for shape-driven segmentation and tracking of the left ventricle. | Knowledge-based segmentation has been explored significantly in medical imaging. Prior anatomical knowledge can be used to define constraints that can improve performance of segmentation algorithms to physically corrupted and incomplete data. In this paper, the objective is to introduce such knowledge-based constraints... |
2,322,392 | Proteus syndrome associated with liver involvement: case report. | We report a patient with proteus syndrome who has epidermal nevus, right-sided asymmetric growth of extremities, pelvis, vertebrae and hemimegalencephaly. This patient also had enlargement of the liver which is not reported before in the proteus syndrome. |
2,322,393 | Effects of ginkgo biloba extract and bilobalide, a main constituent, on the ionic currents in guinea pig ventricular cardiomyocytes. | Effects of Ginkgo biloba extract (GBE, 0.01 to 1 mg/ml) and a main constituent, bilobalide (0.1 to 1 mumol/l), on the action potentials and the underlying ionic currents in guinea pig ventricular cardiomyocytes were investigated using a patch-clamp technique. Both GBE and bilobalide at high concentrations caused depres... |
2,322,394 | Application of endoscopy for a midbrain tumor. | It has been difficult to obtain a biopsy of a midbrain lesion. In addition, proper cerebrospinal fluid diversion should be secured because progressing tumor in the midbrain causes obstructive hydrocephalus. We report on the superiority of flexible neuroendoscopy to treat progressing midbrain tumor.</AbstractText>A 64-y... |
2,322,395 | Giant cyst of the cavum septi pellucidi, cavum Vergae and veli interpositi. | The authors report a case study of a giant cyst of the cavum septi pellucidi, cavum Vergae and veli interpositi spreading to the posterior fossa, and initially treated elsewhere by ventriculoperitoneal shunt, with no resolution of the symptomatology. A few months later the patient was successfully treated by fenestrati... |
2,322,396 | Treatment of posterior third ventricular central neurocytoma with endoscopic biopsy, endoscopic third ventriculostomy and stereotactic radiosurgery. | Central neurocytomas of the posterior third ventricle are rare. These typically benign lesions have recently been shown to respond well to Gamma knife stereotactic radiosurgery (SRS). We present the case of a posterior third ventricle central neurocytoma presenting with aqueduct obstruction. The patient was treated wit... |
2,322,397 | Microanatomy of endoscope-assisted glabellar nasal keyhole approach. | To make a study of the detailed microanatomy of endoscope-assisted glabellar nasal keyhole approach (GNKA) to be used clinically.</AbstractText>10 dry adult Chinese skulls were measured and 10 perfused cadaveric heads were dissected to mimic the GNKA.</AbstractText>Average distances between bilateral supraorbital foram... |
2,322,398 | Positive inotropic effect of endothelin-1 in the neonatal mouse right ventricle. | In neonatal mouse right ventricles, endothelin-1 (ET-1, 1-300 nM) induced a dose-dependent increase in twitch contractions and the dose-response curve was shifted to the right by BQ-123 (10 microM), an endothelin ET(A) receptor antagonist. The ET-1 (100 nM)-induced positive inotropy was accompanied by an increase in [C... |
2,322,399 | Gene therapy-mediated modulation of immune processes in the central nervous system. | Selective interference with immune processes in the central nervous system (CNS) is a very difficult task because of the limitations associated with the delivery of immuno modulatory molecules across the blood brain barrier. Systemic administration of immune-mediators, either by conventional routes or by intramuscularl... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.