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2,322,100 | [Expression of genes related to inflammatory response in myocardium of rats after burn injury]. | To observe expression of genes related to inflammatory response in myocardium of rats after burn injury.</AbstractText>After 40 percent total body surface area (TBSA) of rat was burned gene expression of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), induced nitric oxide synthase (iNOS) and cyto... |
2,322,101 | FAME--a flexible appearance modeling environment. | Combined modeling of pixel intensities and shape has proven to be a very robust and widely applicable approach to interpret images. As such the active appearance model (AAM) framework has been applied to a wide variety of problems within medical image analysis. This paper summarizes AAM applications within medicine and... |
2,322,102 | Venous variations in the region of the third ventricle: the role of MR venography. | In this study, we examined the anatomical variations of the subependymal veins in the region of the foramen of Monro and the third ventricle by MR time of flight (TOF) venography. Fifty healthy subjects, ten patients with third-ventricle tumors, and four patients with lateral-ventricle tumors were included in the study... |
2,322,103 | Responses of chronically hypoxic rat hearts to ischemia: KATP channel blockade does not abolish increased RV tolerance to ischemia. | Chronic hypoxia may precondition the myocardium and protect from ischemia-reperfusion damage. We therefore examined the recovery of left and right ventricular function after ischemia and reperfusion (15 min each) in isolated blood-perfused working hearts from normoxic (Norm) and hypoxic (Hypo; 14 days, 10.5% O(2)) adul... |
2,322,104 | Distribution of mu receptors in the ventral respiratory group neurons; immunohistochemical and pharmacological studies in decerebrate cats. | Immunoreactivity for mu receptors was investigated in 21 bulbar respiratory neurons, individually identified by intracellular recording and labeling with neurobiotin. In 14 of these neurons, effects of iontophoresed morphine were examined. Morphine hyperpolarized the membrane and decreased spike discharges in 4/6 augme... |
2,322,105 | Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum. | Pathological processes, including cerebral ischemia, can enhance neurogenesis in the adult brain, but the fate of the newborn neurons that are produced and their role in brain repair are obscure. To determine if ischemia-induced neuronal proliferation is associated with migration of nascent neurons toward ischemic lesi... |
2,322,106 | Diagnosing death by drowning in fresh water using blood strontium as an indicator. | The interpretation of the level of strontium (Sr) in blood has been demonstrated to be useful in the diagnosis of death by drowning occurred in sea water, but its use in fresh water drownings is not so evident because of the low Sr concentration present in most of fresh water media. In this paper, we show a survey of t... |
2,322,107 | Central effects of rat versus mouse leptin: ingestive behavior and adipose apoptosis. | Leptin decreases food intake, body weight and fat mass while sparing lean mass. Although mouse leptin (ML) and rat leptin (RL) are 95.9% identical, our impression from previous studies was that they were not equally potent in rats. Thus, in the present study, 0 microg (vehicle) or 10 microg of ML or RL was injected int... |
2,322,108 | Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenous IGF-1 and GDNF. | Progenitor cells in the dentate gyrus of hippocampus (DG) and the subventricular zone of lateral ventricles (SVZ) generate new neurons throughout the life of mammals. Cerebral ischemia increases this basal progenitor cell proliferation. The present study evaluated the time frame of proliferation, length of survival and... |
2,322,109 | Cerebral cysticercosis by Taenia crassiceps in a domestic cat. | Cerebral cysticercosis by Taenia crassiceps was diagnosed in an adult female domestic shorthair cat. The animal was euthanized 6 weeks after the initial presentation with signs of vomiting, lethargy, and ataxia. The disease took an intermittent relapsing course with the neurological signs progressing eventually to recu... |
2,322,110 | Voxel-based morphometry detects cortical atrophy in the Parkinson variant of multiple system atrophy. | To determine magnetic resonance imaging (MRI) patterns of brain atrophy in parkinsonian syndromes, we applied voxel-based morphometry (VBM) to segmented gray matter, white matter, and cerebrospinal fluid compartments of T(1)-weighted brain volumes of 12 patients with probable multiple system atrophy-parkinson variant (... |
2,322,111 | Pathomorphological criteria of arrhythmogenic heart. | Pathomorphological criteria of arrhythmogenic heart include structural compartmentalization with primary changes in the right ventricle and interventricular septum, fibro- and lipomatosis of the myocardium, and disseminated coronary obstruction. Ischemic focuses in the conducting system are the site of formation of arr... |
2,322,112 | Novel distribution of calcitonin gene-related peptide in rodent subcommissural organs. | For the first time we showed the presence of CGRP immunoreactivity in the SCO of golden hamsters, Wistar rats and Mongolian gerbils. In hamsters, the intense CGRP-like immunoreactivity was detected in the whole SCO, including Reissner's fiber- and granule-like structures at the ventricular surface of the SCO. The CGRP-... |
2,322,113 | Role of apoptosis and mitosis during human eye development. | The spatial and temporal distribution as well as ultrastructural and biochemical characteristics of apoptotic and mitotic cells during human eye development were investigated in 14 human conceptuses of 4-9 postovulatory weeks, using electron and light microscopy. In the 5th developmental week, apoptotic and mitotic cel... |
2,322,114 | [Intracranial lipomas in paediatrics: a retrospective study of 20 patients]. | Intracranial lipomas (ICL) are congenital malformations that are due to an anomalous differentiation of the primitive meninges.</AbstractText>The purpose of this study is to determine the most frequent symptoms related to ICL in the paediatric age, as well as to evaluate whether they are directly related to their locat... |
2,322,115 | Transcortical-transventricular approach in colloid cysts of the third ventricle: surgical experience with 26 cases. | Colloid cysts of the third ventricle account for 0.5-2% of all intracranial tumors. The treatment of these benign tumors remains controversial, and the best surgical option has not yet been determined. Between 1995 and 2002, 27 patients with colloid cysts of the third ventricle presented at our clinic. Twenty-six under... |
2,322,116 | Unrecognised ventriculitis/meningitis presenting as hydrocephalus in infancy. | Infantile hydrocephalus due to unrecognized neonatal-onset meningitis/ventriculitis, was studied retrospectively using 1991-1998 chart review. Seventy two patients with hydrocephalus were reviewed. Thirteen infants had hydrocephalus associated with active meningitis/ventriculitis which had remained unrecognized. Active... |
2,322,117 | Development of a long-lasting ventricular catheter impregnated with a combination of antibiotics. | A ventricular silicone catheter impregnated with a combination of rifampin and a quinolone was developed in order to prevent ventricular shunt related infections. As model substance for the quinolones we used sparfloxacin, because of its specific physicochemical properties resulting in a quantitative detection also in ... |
2,322,118 | Reactive gliosis in areas around third ventricle in association with epileptogenesis in amygdaloid-kindled rat. | Repeated focal electrical stimulation of the brain is known to produce epileptogenesis, and this phenomenon is recognized as kindling. It is also considered to be a model of temporal lobe epilepsy. In the present study, morphological changes in areas around third ventricle in rat brain were examined according to the pr... |
2,322,119 | Intraventricular haemorrhage and periventricular leukomalacia in Nigerian infants of very low birth weight. | Transfontanelle ultrasound scans were performed on 93 very low birth weight neonates admitted at the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria, between January 1992 and April 1994, to ascertain the pattern and determinants of intraventricular haemorrhage and periventricular leukomalacia. Forty-seve... |
2,322,120 | Selective elimination of I(K,slow1) in mouse ventricular myocytes expressing a dominant negative Kv1.5alpha subunit. | Although previous studies have revealed a role for the voltage-gated K+ channel alpha-subunit Kv1.5 (KCNA5) in the generation of the 4-aminopyridine (4-AP)-sensitive component of delayed rectification in mouse ventricles (IK,slow1), the phenotypic consequences of manipulating IK,slow1 expression in vivo in different (m... |
2,322,121 | A cylindrical model for studying subendocardial ischaemia in the left ventricle. | In this paper a mathematical model of a left ventricle with a cylindrical geometry is presented with the aim of gaining a better understanding of the relationship between subendocardial ischaemia and ST depression. The model is formulated as an infinite cylinder and takes into account the full bidomain nature of cardia... |
2,322,122 | Inferior central sulcus: variations of anatomy and function on the example of the motor tongue area. | We wanted to define the position of the primary motor tongue area (MTA) by using functional magnetic resonance imaging (fMRI) to display the MTA in relation to the inferolateral segment of the central sulcus (CS). The anatomy of the inferolateral segment was analyzed in 24 healthy subjects, using the magnetization prep... |
2,322,123 | A voxel-based morphometric study of nondemented adults with Down Syndrome. | Previous structural brain imaging studies of Down Syndrome (DS) have offered important insights into the underlying morphometric aberrations associated with the condition. These previous studies have relied almost exclusively on classic region-of-interest (ROI)-based morphometry, a method in which a finite number of an... |
2,322,124 | Functional reorganization of brain in children affected with congenital hemiplegia: fMRI study. | Using functional magnetic resonance imaging, the brain activation related to unilateral sequential finger-to-thumb opposition was studied in six children with a right congenital hemiplegia of cortical origin. They were compared to six age-matched controls. In the control group, movements with either hand asymmetrically... |
2,322,125 | Retrograde labeling of mouse spinal descending tracts by a recombinant adenovirus. | The present study tested whether a gene-transfer based upon the retrograde axonal transport of the lacZ adenovirus is effective in the spinal descending tracts of the adult mouse. A small volume of a replication-defective recombinant adenovirus encoding E. coli beta-galactosidase was injected into the upper lumbar cord... |
2,322,126 | Extranodal imaging manifestations of non-Hodgkin's lymphoma. | A series of imaging features of extranodal, multi-systemic involvements in Non-Hodgkin's lymphoma (NHL) were investigated. The clinical data and imaging findings of 16 patients with pathologically proved NHL were retrospectively analyzed. The related literatures were reviewed. Of the 16 cases of NHL, skeletal involveme... |
2,322,127 | [Neurosurgical Embryology. Part 2: Recent data on normal and pathological development of the cortex]. | Understanding how the cortex develops has gained very important new data thanks to both experimental and clinical studies. Experimental studies have shown that: --neurons are generated in the ventricular zone by asymmetric mitoses; --the first cortical region to differentiate is the so-called pre-plate that plays a maj... |
2,322,128 | Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. | Neuropeptide Y (NPY) is a powerful orexigenic neurotransmitter. The NPY Y1 and Y5 receptors have been implicated in mediating the appetite-stimulating activity of NPY. To further investigate the importance of these two receptors in NPY-induced hyperphagia after chronic central administration, we used mice lacking eithe... |
2,322,129 | Percutaneous left ventricular "vent" insertion for left heart decompression during extracorporeal membrane oxygenation. | Description of a novel method of left ventricular decompression by a percutaneous technique under transthoracic echocardiographic guidance.</AbstractText>Case report.</AbstractText>Supraregional cardiac referral center.</AbstractText>PATIENT with end-stage cardiomyopathy.</AbstractText>Percutaneous insertion of a modif... |
2,322,130 | Association between use of antenatal magnesium sulfate in preterm labor and adverse health outcomes in infants.<Pagination><StartPage>613</StartPage><MedlinePgn>613</MedlinePgn></Pagination><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mittendorf</LastName><ForeName>Robert</ForeName><Initials>R</Initials></A... | Seventy patients with bronchial asthma (BA), including 17 with mild asthma, 41 with moderate asthma, and 12 with severe BA, were examined by performing external respiration function test, echocardioscopy, ECG, 24-hour Holter monitoring, lipid metabolic studies. Myocardial ischemia was detected in 47% of the patients wi... |
2,322,131 | Inhibition of membrane-associated calcium-independent phospholipase A2 as a potential culprit of anthracycline cardiotoxicity. | Administration of anthracyclines, a family of highly effective anticancer drugs, is associated with a cumulative dose-related cardiomyopathy, the etiology of which remains poorly understood. We have discovered that administration of the anthracyclines leads to a marked inhibition of membrane-associated calcium-independ... |
2,322,132 | Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta. | The purpose of this study is to test the hypothesis that mechanical and electrical activity in adult rat ventricular myocytes (ARVM) alters responses to proapoptotic and prosurvival ligands. The effects of electrical stimulation on myocyte survival, stress signaling, response to beta-adrenergic receptor (beta-AR)-stimu... |
2,322,133 | Zidovudine-induced alterations in the heart and vascular smooth muscle of the rat. | We investigated the effects of zidovudine (AZT) on cardiac and vascular smooth muscle function and morphology in rats.</AbstractText>Four adult male Wistar-Kyoto rats received AZT in drinking water for 240 days; four rats served as controls. Echocardiographic examination and systolic blood pressure (SBP) measurement we... |
2,322,134 | Attentional functions of cortical cholinergic inputs: what does it mean for learning and memory? | The hypothesis that cortical cholinergic inputs mediate attentional functions and capacities has been extensively substantiated by experiments assessing the attentional effects of specific cholinotoxic lesions of cortical cholinergic inputs, attentional performance-associated cortical acetylcholine release, and the eff... |
2,322,135 | Acetylcholine modulation of neural systems involved in learning and memory. | Extensive evidence supports the view that cholinergic mechanisms modulate learning and memory formation. This paper reviews evidence for cholinergic regulation of multiple memory systems, noting that manipulations of cholinergic functions in many neural systems can enhance or impair memory for tasks generally associate... |
2,322,136 | N1-acetyl-N2-formyl-5-methoxykynuramine is a product of melatonin oxidation in rats. | The product of melatonin oxidation, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), was synthesized and a method for its determination in biological samples was developed. High performance liquid chromatography (HPLC) with fluorescence detection provided good sensitivity and selectivity. Wavelengths of 350 and 480 nm w... |
2,322,137 | Magnetic resonance imaging in foetuses with bilateral moderate ventriculomegaly and suspected anomaly of the corpus callosum on ultrasound scan. | The diagnosis of anomalies of the corpus callosum (ACC) in foetuses with bilateral moderate ventriculomegaly (BMV) is difficult by means of ultrasound scan. The aim of this study was to examine the value of the additional investigation with magnetic resonance imaging (MRI) in foetuses with BMV and suspected ACC on ultr... |
2,322,138 | [Myocardium of mdx mice contains factor(s) that damage DNA structure and retard DNA reparation after gamma-irradiation (experiences in modeling system)]. | We studied the action of saline extracts of ventricle myocard (EM) of C57BL and mdx mice on DNA structure and repair of one-strand breaks of DNA in a modelling system. The system involves DNA repair in E. coli WP2 cells after gamma-irradiation. Using standard technique, DNA reparation was estimated on measuring the spe... |
2,322,139 | [Transient periventricular echodensities (TPE) in preterm infants under 1500 gramms: an analysis of the outcome of the last 10 years]. | The aim of our study was to analyze neurodevelopmental outcome in preterm infants with TPE.</AbstractText>46 preterm infants with a birthweight (BW) < or = 1500 g were included in the study. They all had TPE in parieto-occipital location (some combined with frontal flares). Exclusion criteria were PVL II-IV, intrave... |
2,322,140 | Functional characterisation of the active ascorbic acid transport into cerebrospinal fluid using primary cultured choroid plexus cells. | Crossing the blood-CSF barrier is an important pathway for certain nutrients to enter the CNS. Cultured choroid plexus epithelial cells are a potent model system to study active transport properties of this tissue in vitro. In the present study this in vitro model was used to analyse ascorbic acid transport across the ... |
2,322,141 | The distributions and signaling directions of the cerebrospinal fluid contacting neurons in the parenchyma of a rat brain. | Many studies have been made on the distributions of CSF contacting neurons (CSF-CNs) in the parenchyma of the brain with horseradish peroxidase (HRP) or autoradiographics. A significant amount of data has shown that both HRP and autoradiographical substances could pass freely through the spaces of ependyma into the par... |
2,322,142 | Overexpression of calpastatin by gene transfer prevents troponin I degradation and ameliorates contractile dysfunction in rat hearts subjected to ischemia/reperfusion. | Calpain is a Ca(2+)-activated neutral protease that supposedly plays a key role in myocardial dysfunction following ischemia/reperfusion, by degrading certain proteins involved in the contraction mechanism. It is possible that overexpression of calpastatin, an endogenous calpain inhibitor, lessens contractile dysfuncti... |
2,322,143 | Tyrosine kinases inhibitors block Fas-mediated deleterious effects in normoxic and hypoxic ventricular myocytes. | Experimental evidences suggest an important role for Fas receptor activation in a wide range of myocardial pathologies, which are associated with a variety of arrhythmias and mechanical dysfunction. Our recent studies have shown that Fas-mediated arrhythmias and mechanical disturbances of ventricular myocytes can be ac... |
2,322,144 | Brief altitude exposure in New Zealand white rabbits (Oryctolagus cuniculus) does not produce elevated intracranial pressure. | Our intent was to observe the effect of simulated altitude exposure on the intracranial pressure (ICP) of New Zealand white rabbits. It is theorized that the hypoxia of high altitude causes a rise in ICP, which may play a role in the pathogenesis of acute mountain sickness (AMS). Dexamethasone is a medication used to t... |
2,322,145 | Distribution of 125J-labeled leucopyrokinin (LPK) in rats. | The distribution in parts of the brain and internal organs of 125J-labeled leucopyrokinin (LPK), an insect myotropic peptide injected into the lateral brain ventricle was determined in rats. A high accumulation of this peptide in adrenals and in the hypothalamus and hippocampus of the brain was found. A lesser but sign... |
2,322,146 | Cardiac myosin phenotype remodelling following adrenodemedullectomy and chronic 6-hydroxydopamine in male Sprague-Dawley rats. | An increase was previously found in relative beta myosin heavy chain (MyHC) in the right ventricle of rats following thoracic spinal transection. It was hypothesized that the MyHC remodelling that was observed might be due, in part, to autonomic influences on the right ventricle.</AbstractText>To evaluate cardiac myosi... |
2,322,147 | The functional domains of human ventricular myosin light chain 1. | The biological functions of the myosin light chain 1 (LC1) have not been clearly elucidated yet. In this work we cloned and expressed N- and C- terminal fragments of human ventricular LC1 (HVLC1) containing amino acid residues 1-98 and 99-195 and two parts, NN and NC of N fragment in GST-fusion forms, respectively. Usi... |
2,322,148 | Brain transplantation of genetically engineered human neural stem cells globally corrects brain lesions in the mucopolysaccharidosis type VII mouse. | In the present study, we investigated the feasibility of using human neural stem cells (NSCs) in the treatment of diffuse central nervous system (CNS) alterations in a murine model of mucopolysaccharidosis VII (MPS VII), a lysosomal storage disease caused by a genetic defect in the beta-glucuronidase gene. An immortali... |
2,322,149 | Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system. | Voltage-dependent K(+) channels play a pivotal role in controlling cellular excitability within the nervous system. The aim of the present study was to investigate the expression in the adult rat brain of the three ether-a-gogo-related gene (ERG) family members ERG1, ERG2, and ERG3, encoding for K(+) channel subunits. ... |
2,322,150 | Destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter. | 1. The ability to target specific neurons can be used to produce selective neural lesions and potentially to deliver therapeutically useful moieties for treatment of disease. In the present study, we sought to determine if a monoclonal antibody to the dopamine transporter (anti-DAT) could be used to target midbrain dop... |
2,322,151 | Secretin activates visceral brain regions in the rat including areas abnormal in autism. | 1. The aim of this study was to determine whether central networks are involved in the presumptive behavioral and autonomic regulatory actions of secretin, a gut hormone that has been reported to have ameliorative effects in autistic children. 2. Central neural responses monitored by regional c-fos gene expression were... |
2,322,152 | Immunocytochemical characterisation of the wall of the bovine lateral ventricle. | The cytoarchitecture of the walls of the bovine lateral ventricles was investigated by the use of immunocytochemistry. We defined three types of walls. Type 1 lined regions of white matter and had ciliated cuboidal ependyma, a few subependymal cells and a narrow subjacent glial layer. Type 2 lined the striatum and poss... |
2,322,153 | Right ventricular infarction during a lung lobectomy in a patient with chronic obstructive pulmonary disease: report of a case. | A 63-year-old man with a low forced expiratory volume in 1 s underwent a wedge resection for peripheral lung cancer; however, it relapsed in the residual lobe. We decided that a lobectomy was feasible after further examinations focusing on gas exchange. During the lobectomy right ventricle myocardial infarction occurre... |
2,322,154 | Septo-optic dysplasia plus: case report. | Septo-optic dysplasia (SOD) is a syndrome composed by optic nerve and septum pellucidum dysgenesis. It has been classified into two subsets according to the embryogenesis and the neuropathological findings. Basically, the difference between these two groups is the presence or not of schizencephaly. The term SOD-Plus wa... |
2,322,155 | The natural history of ventriculomegaly and tonsillar herniation in children with posterior fossa tumours--an MRI study. | Posterior fossa tumours in children predispose to hydrocephalus, although the natural history is unclear and the need for drainage of the ventricles is controversial. We report on the natural history of ventriculomegaly and tonsillar herniation, as seen on serial MRI scans in children with posterior fossa tumours.</Abs... |
2,322,156 | Increased ICAM-1 and VCAM-1 expression in the brains of autoimmune mice. | Pathogenic mechanisms of central nervous system (CNS) involvement in systemic lupus erythematosus (SLE) remain unknown. We recently reported the presence of autoantibodies in the brain tissue ex vivo of autoimmune MRL/lpr mice. We postulated that at least some of these autoantibodies are produced in situ because of B-c... |
2,322,157 | Brain volumes as predictor of outcome in recent-onset schizophrenia: a multi-center MRI study. | Gray matter brain volume decreases have been found in patients with schizophrenia as compared to healthy control subjects measured by using Magnetic Resonance Imaging (MRI). An association has been suggested between decreased gray matter volume and poor outcome in chronically ill patients with schizophrenia. The presen... |
2,322,158 | Role of Ca2+-activated Cl- current during proarrhythmic early afterdepolarizations in sheep and human ventricular myocytes. | The proarrhythmic early afterdepolarizations (EADs) during phase-2 of the cardiac action potential (phase-2 EADs) are associated with secondary Ca2+-release of the sarcoplasmic reticulum. This makes it probable that the Ca2+-activated Cl- current [ICl(Ca)] is present during phase-2 EADs. Activation of ICl(Ca) during ph... |
2,322,159 | Heart rate variability before ventricular arrhythmias in patients with coronary artery disease and an implantable cardioverter defibrillator. | Changes in autonomic regulation of the heart may be responsible for the occurrence of arrhythmias. Although a decrease in 24-hour heart rate variability is a strong predictor of subsequent arrhythmias in patients with heart disease, many questions remain unanswered concerning changes in heart rate and heart rate variab... |
2,322,160 | Quantitative assessment of myocardial scar in delayed enhancement magnetic resonance imaging. | To characterize the extent and distribution of left ventricular myocardial scar in delayed enhancement magnetic resonance imaging (MRI).</AbstractText>Delayed enhancement images from 18 patients were categorized into three groups based on myocardial scar appearance: discrete myocardial infarction (N = 10), diffuse fibr... |
2,322,161 | Coxsackievirus B3 and the neonatal CNS: the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease. | Neonates are particularly susceptible to coxsackievirus infections of the central nervous system (CNS), which can cause meningitis, encephalitis, and long-term neurological deficits. However, viral tropism and mechanism of spread in the CNS have not been examined. Here we investigate coxsackievirus B3 (CVB3) tropism an... |
2,322,162 | Planar measurements of foetal lateral ventricles. | To compare the linear dimensions (width) of the foetal atrium and occipital horns to their areas, 31 foetuses (15-24 weeks, C-R 12.5-23.5 mm) from spontaneous abortions were evaluated. Images of the axial sections of the brains were transferred to computer and Scion for Windows 98 software was used for image analysis. ... |
2,322,163 | Tangential migration of neocortical neurons in early human foetuses. | The aim of the present study is to describe the tangential migration of cortical neurons in early human foetuses aged 9-11 weeks. Histological sections showed that in this early period of development most of the neurons migrate along radial glia, but there is also tangential migration, especially from the lateral emine... |
2,322,164 | Symptomatic cysts of the cavum septi pellucidi and cavum vergae: the role of endoscopic neurosurgery in the treatment of four consecutive cases. | Cavum septi pellucidi and cavum vergae are generally asymptomatic fluid collections between the leaves of the septum pellucidum and are present in approximately 15 % of adult brains. These cavities rarely enlarge and become symptomatic causing significant neurological dysfunction as a result of obstruction of the inter... |
2,322,165 | Unsuccessful third ventriculostomy for occlusive hydrocephalus. | For non-communicating hydrocephalus, neuroendoscopic third ventriculostomy has become a major choice. But sometimes, the procedure results in failure. Typically, impairment of a distal CSF absorption, a preexisting arachnoid membrane just below the fenestrated site and a glial scarring of fenestrated site were pointed ... |
2,322,166 | Neuroendoscopy: one year of experience--personal results, observations and limits. | After reading reports of successful neuroendoscopic treatment of hydrocephalus, colloid cysts and arachnoid cysts as well as tumor biopsy, we started using endoscopic procedures in our Department, one year ago. One surgeon (E.S.) skilled in the Decq Endoscope, performed a series of sixteen procedures, from January 2001... |
2,322,167 | Pro and cons of different designs of rigid endoscopes. | Experience with more than 200 neuroendoscopic procedures taught us the advantages and disadvantages of the different endoscope designs. Using an endoscope with a sheath with separate channels for the endoscope, the instruments as well as for rinsing and suction we found advantages in rinsing properties, handling, and p... |
2,322,168 | The mechanism of fornix lesions in 3rd ventriculostomy. | Fornix lesions as a complication of 3rd ventriculostomy are rare and almost not reported. However, in our series of 94 procedures we observed 5 fornix lesions. Although we did not find any clinical deterioration, we were alarmed by these unexpected incidences and analysed the mechanism. All fornix lesions occurred usin... |
2,322,169 | Cardiovascular changes during endoscopic third ventriculostomy. | During an endoscopic third ventriculostomy (ETV) a sudden increase in intracranial pressure (ICP) may occur at any time. In the literature little attention has been paid to the early detection of such an increase. In particular the occurrence of a 'Cushing reflex' has not been discussed in this context. Therefore, we h... |
2,322,170 | Interactive image-guided management of colloid cysts of the third ventricle. | Image guidance provides a three-dimensional view of the lesion and allows the surgeon to plan a surgical strategy that takes the relationship of the lesion and the surrounding brain into account. We evaluated the degree of resection and the functional outcome of patients with colloid cysts from the third ventricle subm... |
2,322,171 | Adult cardiac stem cells are multipotent and support myocardial regeneration. | The notion of the adult heart as terminally differentiated organ without self-renewal potential has been undermined by the existence of a subpopulation of replicating myocytes in normal and pathological states. The origin and significance of these cells has remained obscure for lack of a proper biological context. We r... |
2,322,172 | Germinoma in the fourth ventricle. | A 33-year-old male presented with trigeminal, abducens, and facial nerve pareses associated with cerebellar signs. Magnetic resonance imaging showed a homogeneously enhanced mass occupying the lower half of the fourth ventricle and attached to the floor of the fourth ventricle. The mass was subtotally removed. The hist... |
2,322,173 | Linear accelerator radiosurgery in treatment of central neurocytomas. | The purpose of this report was to review our experience with stereotactic radiosurgery in the management of patients with residual neurocytomas after initial surgery.</AbstractText>Between October 1996 and December 2001, four patients with central neurocytoma were treated by surgery and subsequently underwent linear ac... |
2,322,174 | Arterial vascularization of the human thalamus: extra-parenchymal arterial groups. | The problem of the arterial vascularization of the human thalamus has been debated at length. Anatomical references concerning the thalamic arterial groups are contradictory and complex, preventing any solid application in practice. It is, therefore, difficult to produce reliable anatomical radio-clinical correlation. ... |
2,322,175 | Hypercholesterolemia-induced long-term increase of macrophages in the myocardium of New Zealand White rabbits. | The effect of hypercholesterolemia on the number, immunological phenotype and oxidative stress-dependent processes of macrophages (MPhi) and dendritic cells (DC) was studied in New Zealand White rabbits. The left ventricular myocardium was immunohistochemically analyzed in group I (control), which was on standard chow,... |
2,322,176 | [A case of multiple sclerosis with incongruous homonymous hemianopia due to lateral geniculate body lesion]. | We report a rare case of a 31-year-old woman who was diagnosed as multiple sclerosis with homonymous hemianopia due to a demyelinative lesion in the lateral geniculate body. Paresthesia appeared in the distal parts of both legs from September, 2002. She complained of loss of visual field in both eyes 2 months later. Si... |
2,322,177 | Cyclic AMP and cyclic GMP independent stimulation of ventricular calcium current by peroxynitrite donors in guinea pig myocytes. | We investigated the potential involvement of peroxynitrite (ONOO(-)) in the modulation of calcium current (I(Ca)) in guinea pig ventricular myocytes with the whole-cell patch clamp technique and with cyclic AMP (cAMP) measurements. Because of the short half-life of ONOO(-) at physiological pH, we induced an increase in... |
2,322,178 | Rapid progression of midventricular obstruction in adults with double-chambered right ventricle. | The purpose of this study was to determine the rate of progression of midventricular obstruction in adolescents and adults with double-chambered right ventricle.</AbstractText>Clinical and echocardiographic findings in 45 patients (mean age 26 +/- 6 years, range 15-44) diagnosed with double-chambered right ventricle we... |
2,322,179 | Rapid computed tomography technique to measure ventricular volumes in the child with suspected ventriculoperitoneal shunt failure II. Clinical application. | Assessment of ventricular volume change is critical in the child with suspected shunt failure. Minimal increases may represent high pressures in the child with reduced ventricular compliance but are difficult to detect subjectively. Objective techniques described limit anatomic sampling and are time intensive. The purp... |
2,322,180 | Further studies on cortical tangential migration in wild type and Pax-6 mutant mice. | In this study we present new data concerning the tangential migration from the medial and lateral ganglionic eminences (MGE and LGE) to the cerebral cortex during development. We have used Calbindin as a useful marker to follow the itinerary of tangential migratory cells during early developmental stages in wild-type a... |
2,322,181 | The brain's interstitial clefts and their glial walls. | The heterogeneous contents of the CNS interstitial clefts and the configuration of their astrocytic walls may be regionally variable. Astrocytic processes of the glia limitans, in normal midbrain and in astroglial scars, form thin, parallel, concentric sheets comprising the walls of narrow interstitial clefts. There is... |
2,322,182 | Dexrazoxane (ICRF-187) protects cardiac myocytes against doxorubicin by preventing damage to mitochondria. | The clinically approved antioxidant cardioprotective agent dexrazoxane (ICRF-187) was examined for its ability to protect neonatal rat cardiac myocytes from doxorubicin-induced damage. Doxorubicin is thought to induce oxidative stress on the heart muscle, both through reductive activation to its semiquinone form, and b... |
2,322,183 | Citrobacter koseri brain abscess in the neonatal rat: survival and replication within human and rat macrophages. | A unique feature of Citrobacter koseri is the extremely high propensity to initiate brain abscesses during neonatal meningitis. Previous clinical reports and studies on infant rats have documented many Citrobacter-filled macrophages within the ventricles and brain abscesses. It has been hypothesized that intracellular ... |
2,322,184 | Cell coupling between ventricular myocyte pairs from connexin43-deficient murine hearts. | Mice with cardiac-restricted inactivation of the connexin43 gene (CKO mice) have moderate slowing of ventricular conduction and lethal arrhythmias. Mechanisms through which propagation is maintained in the absence of Cx43 are unknown. We evaluated gap junctional conductance in CKO ventricular pairs using dual patch cla... |
2,322,185 | Agouti-related protein increases food hoarding more than food intake in Siberian hamsters. | Agouti-related protein (AgRP), an endogenous melanocortin 3/4 receptor antagonist, appears to play an important role in the control of food intake and energy balance because exogenous administration in rats and overexpression in mice result in hyperphagia and body mass gain. Furthermore, arcuate nucleus AgRP mRNA is in... |
2,322,186 | Hystereses in the force-length relation and regulation of cross-bridge recruitment in tetanized rat trabeculae. | Various mechanisms have been suggested to explain cardiac force-length Ca2+ relations. The existence of a cooperativity mechanism, whereby cross-bridge (XB) recruitment is affected by the number of active XBs, suggests that the force response to length oscillations should lag length oscillations. Consequently, the osci... |
2,322,187 | Stem cells from the adult human brain develop into functional neurons in culture. | Recent research communications indicate that the adult human brain contains undifferentiated, multipotent precursors or neural stem cells. It is not known, however, whether these cells can develop into fully functional neurons. We cultured cells from the adult human ventricular wall as neurospheres and passed them at t... |
2,322,188 | Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases. | Iron has a variety of functions in cellular organisms ranging from electron transport and DNA synthesis to adenosine triphosphate (ATP) and neurotransmitter synthesis. Failure to regulate the homeostasis of iron can lead to cognition and demyelination disorders when iron levels are deficient, and to neurodegenerative d... |
2,322,189 | CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors. | To identify proteins interacting with the C-terminal cytoplasmic tail of the dopamine D(3) receptor (D(3)R), we used the two-hybrid system to screen a rat brain cDNA library. We isolated three partial cDNAs encoding, respectively, for the MUPP1 multi-PDZ protein, for the N-terminal region of radixin, for GIPC and for a... |
2,322,190 | A new norepinephrine transporter imaging agent for cardiac sympathetic nervous function imaging: radioiodinated (R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine. | Changes of the cardiac norepinephrine transporter (NET) have been reported in several cardiac failures. (R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine (MIPP), the 3-phenoxy-3-phenylpropylamine analogue iodinated at the 2-position of the phenoxy ring, was synthesized and evaluated as a potential radiopharmaceutical ... |
2,322,191 | Ultrastructural localization of vimentin immunoreactivity and gene expression in tanycytes and their alterations in hamsters kept under different photoperiods. | Tanycytes are located in the basolateral walls of the third ventricle. By light- and electron-microscopic immunohistochemistry, we demonstrated that the tanycytes of Djungarian hamsters were intensely immunostained with the vimentin monoclonal antibody V9. The cells always extended long radial processes in which aggreg... |
2,322,192 | The role of 70-degree telescopic examination during direct laryngoscopic evaluation of laryngeal cancers. | Endoscopy has currently been an indispensable method in many areas of otorhinolaryngology, especially in paranasal sinus surgery. Telescopic evaluation of the larynx has not drawn much attention. In this study, a 70-degree angled rigid telescope was used along with computerized tomography (CT), indirect and direct lary... |
2,322,193 | Primary intraventricular brain abscess. | We report a primary intraventricular brain abscess in a 13-year-old boy. We discuss possible explanations for this rare occurrence. |
2,322,194 | MRI estimation of the arterial input function in mice. | Dynamic contrast-enhanced (DCE) MRI offers the potential to provide quantitative maps of tumor perfusion parameters and is therefore expected to play an important role in the study of cancer in small animal models. Extraction of such information from DCE-MRI data requires a methodology for determination of the arterial... |
2,322,195 | [Obsessive-compulsive disorder in a patient with septum pellucidum cyst. Psychiatric and psychologic case study]. | The aim of this paper is to introduce the bases of neurobiology, embryology and pathology of one of the important structures of the limbic system-septum pellucidum. The presented patient was diagnosed with a septum pellucidum cyst, OCD and depression. The following diagnostic methods have been applied: Beck Depression ... |
2,322,196 | [Cognitive dysfunction in 32 diffuse axonal injury cases]. | In acute stage of traumatic brain injury, it is not easy to diagnose diffuse axonal injury (DAI) by computer imaging. Even in chronic stage, DAIs occasionally show no remarkable abnormality by ordinal CT or MRI images. We retrospectively studied 32 DAI cases by the Functional Independence Measure (FIM), a battery of ne... |
2,322,197 | Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576. | Current Alzheimer's disease (AD) research has established the fact that excessive genesis of Abeta derived from amyloidogenic processing of beta-amyloid (Abeta) precursor protein is fundamental to AD pathogenesis. There has been considerable interest in using immunization strategies for clearing excessive Abeta. Studie... |
2,322,198 | [Central neurocytoma: case report]. | The authors report a case of intraventricular tumor. The tumor was initially misdiagnosed as an oligodendroglioma but later proved to be a central neurocytoma. The imaging and histopathological features are reviewed. The immunopositivity allows a diagnosis of neurocytoma. Prognosis is favorable following total surgical... |
2,322,199 | The aminotetraline derivative (+/-)-(R,S)-5,6-dihydroxy-2-methylamino-1,2,3,4-tetrahydro-naphthalene hydrochloride (CHF-1024) displays cardioprotection in postischemic ventricular dysfunction of the rat heart. | To analyze the protective effects of the aminotetraline derivative (+/-)-(R,S)-5,6-dihydroxy-2-methylamino-1,2,3,4-tetrahydro-naphthalene hydrochloride (CHF-1024), a compound endowed with DA2-dopaminergic/alpha2-adrenergic receptor agonistic activity, in myocardial ischemia/reperfusion damage. A model of isolated and p... |
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