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2,326,500 | Fast automatic myocardial segmentation in 4D cine CMR datasets. | A novel automatic 3D+time left ventricle (LV) segmentation framework is proposed for cardiac magnetic resonance (CMR) datasets. The proposed framework consists of three conceptual blocks to delineate both endo and epicardial contours throughout the cardiac cycle: (1) an automatic 2D mid-ventricular initialization and s... |
2,326,501 | Central hydrogen sulphide mediates ventilatory responses to hypercapnia in adult conscious rats. | Hydrogen sulphide (H2S) is endogenously produced and plays an important role as a modulator of neuronal functions; however, its modulatory role in the central CO2 chemoreception is unknown. The aim of the present study was to assess the role of endogenously produced H2S in the ventilatory response to hypercapnia in adu... |
2,326,502 | Neuropsychological follow-up at school age of children with asymmetric ventricles or unilateral ventriculomegaly identified in utero. | To examine the long-term neuropsychological outcome of children with a prenatal diagnosis of asymmetric ventricles or unilateral ventriculomegaly.</AbstractText>A clinic-based neuropsychological study.</AbstractText>Paediatric neurology clinic.</AbstractText>Thirty-three of 41 children, previously assessed at kindergar... |
2,326,503 | Prenatal molecular diagnosis of X-linked hydrocephalus via a silent C924T mutation in the L1CAM gene. | We present a case of a patient whose L1CAM gene in X-chromosome has a C924T transition. Her first son's ventriculomegaly was prenatally detected. A mature infant was born, his head circumference was large, and thumbs were bilaterally adducted. X-linked hydrocephalus (XLH) was suspected. The DNA examination revealed tha... |
2,326,504 | Sickle cell disease in children: chronic complications and search of predictive factors for adverse outcomes. | Sickle cell disease (SCD) has extremely variable phenotypes, and several factors have been associated with the severity of the disease.</AbstractText>To analyze the chronic complications of SCD and look for predictive risk factors for increased severity and number of complications.</AbstractText>Retrospective study inc... |
2,326,505 | Prognosis by tumor location in adults with intracranial ependymomas. | Intracranial ependymomas are rare tumors in adults. Thus, factors affecting prognosis are poorly understood. We performed a study to investigate whether tumor location is an important prognostic factor in adults who undergo surgery for intracranial ependymomas. PubMed was searched to identify studies that reported clin... |
2,326,506 | To repeat or to recreate: a contralateral posterior interhemispheric transfalcine transprecuneus approach for recurrent meningiomas at the trigone of the lateral ventricle. | Surgery in the trigone of the lateral ventricle remains a challenge for neurosurgeons. In recurrent trigonal meningiomas (RTM), the disturbance of normal anatomic structures and adhesion due to previous surgeries, significant oedema, and their malignant properties heighten the difficulties associated with their surgica... |
2,326,507 | Hippocampal GLP-1 receptors influence food intake, meal size, and effort-based responding for food through volume transmission. | Glucagon-like peptide-1 (GLP-1) is produced in the small intestines and in nucleus tractus solitarius (NTS) neurons. Activation of central GLP-1 receptors (GLP-1Rs) reduces feeding and body weight. The neural circuits mediating these effects are only partially understood. Here we investigate the inhibition of food inta... |
2,326,508 | Progressive reduction in cortical thickness as psychosis develops: a multisite longitudinal neuroimaging study of youth at elevated clinical risk. | Individuals at clinical high risk (CHR) who progress to fully psychotic symptoms have been observed to show a steeper rate of cortical gray matter reduction compared with individuals without symptomatic progression and with healthy control subjects. Whether such changes reflect processes associated with the pathophysio... |
2,326,509 | Intrauterine diagnosis and pathology of fetal choroid plexus carcinoma--a case study. | This is a case report of a 39-year-old pregnant woman whose fetus was found to have a large hydrocephalus on routine prenatal ultrasound at the 29th gestational week. A 56 mm × 73 mm mass was detected in the fetal brain arising from the brainstem and invading the third cerebral ventricle. On the subsequent fetal c... |
2,326,510 | Large/giant meningiomas of posterior third ventricular region: falcotentorial or velum interpositum? | Surgical excision of rare, large-to-giant posterior third ventricular (PTV) meningiomas [including velum-interpositum meningiomas (VIM; postero-superior venous complex displacement; without falco-tentorial attachment) and falco-tentorial meningiomas (FTM; falco-tentorial attachment; displacing major veins antero-inferi... |
2,326,511 | Biportal endoscopic removal of choroid papilloma of the lateral ventricle in a child. | The article is devoted to the use of minimally invasive techniques for removing intraventricular tumors; this topic is currently relevant to pediatric neurosurgery. As an example, a clinical case of complete removal of a choroid plexus papilloma in a child using the neuroendoscopic technique through the biportal approa... |
2,326,512 | Biological features and long-term results of comprehensive treatment of brain tumors in infants. | Complete removal is the treatment standard for most brain tumors. Outcomes of subsequent comprehensive treatment depend on biological features, the histological structure of the tumor, and radicality of surgery. The aim of this work was to study the morphological features of brain tumors in infants and to analyze long-... |
2,326,513 | Targeted inactivation of Cerberus like-2 leads to left ventricular cardiac hyperplasia and systolic dysfunction in the mouse. | Previous analysis of the Cerberus like 2 knockout (Cerl2-/-) mouse revealed a significant mortality during the first day after birth, mostly due to cardiac defects apparently associated with randomization of the left-right axis. We have however, identified Cerl2-associated cardiac defects, particularly a large increase... |
2,326,514 | Features of intraventricular tanycytic ependymoma: report of a case and review of literature. | Tanycytic ependymoma is the rarest variant of ependymoma and occurs primarily in the spinal cord. Intracranial cases are even rarer. Only 9 ventricular and 5 subcortical tanycytic ependymoma have been reported in the literature. Amongst the 9 ventricular cases, only one tumor arose from the third ventricle. We report h... |
2,326,515 | N-cadherin promotes recruitment and migration of neural progenitor cells from the SVZ neural stem cell niche into demyelinated lesions. | Discrete cellular microenvironments regulate stem cell pools and their development, as well as function in maintaining tissue homeostasis. Although the signaling elements modulating neural progenitor cells (NPCs) of the adult subventricular zone (SVZ) niche are fairly well understood, the pathways activated following i... |
2,326,516 | Dietary salt restriction in hyperthyroid rats. Differential influence on left and right ventricular mass. | This study assessed the impact of salt restriction on cardiac morphology and biochemistry and its effects on hemodynamic and renal variables in experimental hyperthyroidism. Four groups of male Wistar rats were used: control, hyperthyroid, and the same groups under low salt intake. Body weight, blood pressure (BP), and... |
2,326,517 | Metformin promotes focal angiogenesis and neurogenesis in mice following middle cerebral artery occlusion. | Current studies demonstrated that metformin is not only a hypoglycemic drug, but also a neuro-protective agent. However, the effect of metformin during ischemic brain injury is unclear. The aim of the present study is to explore the effect of metformin during ischemic brain injury. Adult male CD1 mice underwent 90min t... |
2,326,518 | A dual role for planar cell polarity genes in ciliated cells. | In the nervous system, cilia dysfunction perturbs the circulation of the cerebrospinal fluid, thus affecting neurogenesis and brain homeostasis. A role for planar cell polarity (PCP) signaling in the orientation of cilia (rotational polarity) and ciliogenesis is established. However, whether and how PCP regulates cilia... |
2,326,519 | Connatal cyst in a preterm twin infant with maternal comorbidities. | Connatal cysts are rare but recognized periventricular cysts that represent anatomic variants and are associated with good neurological outcomes. These cysts can be differentiated from cysts that portend graver prognoses by their location in relation to the ventricles, size, laterality, and temporal resolution.</Abstra... |
2,326,520 | Dynamic clamp as a tool to study the functional effects of individual membrane currents. | Today, the patch-clamp technique is the main technique in electrophysiology to record action potentials or membrane current from isolated cells, using a patch pipette to gain electrical access to the cell. The common recording modes of the patch-clamp technique are current clamp and voltage clamp. In the current clamp ... |
2,326,521 | Stage-specific changes in neurogenic and glial markers in Alzheimer's disease. | Reports of altered endogenous neurogenesis in people with Alzheimer's disease (AD) and transgenic AD models have suggested that endogenous neurogenesis may be an important treatment target, but there is considerable discrepancy among studies. We examined endogenous neurogenesis and glia changes across the range of path... |
2,326,522 | Cardioprotection afforded by exercise training prior to myocardial infarction is associated with autonomic function improvement. | It has been suggested that exercise training (ET) protects against the pathological remodeling and ventricular dysfunction induced by myocardial infarction (MI). However, it remains unclear whether the positive adjustments on baroreflex and cardiac autonomic modulations promoted by ET may afford a cardioprotective mech... |
2,326,523 | Three-dimensional reconstruction of a cardiac outline by magnetocardiography. | A 3-D cardiac visualization is significantly helpful toward clinical applications of magnetocardiography (MCG), but the cardiac reconstruction requires a segmentation process using additional image modalities. This paper proposes a 3-D cardiac outline reconstruction method using only MCG measurement data without furthe... |
2,326,524 | Impact of heavy load activity on cardiovascular system: echocardiographic assessment of informal construction workers heart in Cameroon. | Physiological cardiac hypertrophy and dilation are common findings in heavy physical load activity. We carried out this study to investigate the relationship between construction work and cardiac parameters adaptations, by comparing healthy masons to office workers on heart ultrasound.</AbstractText>The study was carri... |
2,326,525 | Large right ventricular thrombus. | Right ventricular thrombosis is a rare yet potentially fatal condition. It has been described in association with hypercoagulability states, autoimmune diseases and dilated cardiomyopathy. Echocardiography constitutes the election tool for diagnosis and characterization of these entities, allowing for the differentiati... |
2,326,526 | Safety of Ommaya reservoirs in children with brain tumors: a 20-year experience with 5472 intraventricular drug administrations in 98 patients. | The Ommaya reservoir facilitates repetitive delivery of drugs into the CSF and is a pharmacologically rational system for intrathecal chemotherapy. Because previous studies have found a high rate of infection and other complications we herein studied our experience with this device. Between 1993 and 2013, 98 children w... |
2,326,527 | A retrospective study on the course and outcome of fetal ventriculomegaly. | To evaluate the outcomes associated with fetal ventriculomegaly.</AbstractText>Reports of women who underwent ultrasound scanning between 18 and 36 weeks of gestation during the period from January 1, 2000, to December 31, 2010, were reviewed. According to the defined severity of ventriculomegaly of affected fetuses, t... |
2,326,528 | The female human heart at rest and during exercise: a review. | Sexual dimorphism exists in numerous aspects of exercise physiology. One area that has long been debated is the potential of sex differences in cardiac structure and function. Anthropometric differences exist between males and females, and the relationship between absolute body size and cardiac structure dictate that m... |
2,326,529 | High-protein-low-carbohydrate diet: deleterious metabolic and cardiovascular effects depend on age. | High-protein-low-carbohydrate (HP-LC) diets have become widespread. Yet their deleterious consequences, especially on glucose metabolism and arteries, have already been underlined. Our previous study (2) has already shown glucose intolerance with major arterial dysfunction in very old mice subjected to an HP-LC diet. T... |
2,326,530 | Anti-apoptotic potency of TNFR:Fc gene in ischemia/ reperfusion-induced myocardial cell injury. | The aim of the study was to investigate the anti-apoptotic potency of TNFR:Fc gene in ischemia/reperfusion-induced myocardial cell injury and hypoxia/reoxygenation-induced H9c2 rat cardiomyocytes injury. Rats were randomly divided into the following groups (n=8): (1) sham operation group; (2) ischemia-reperfusion (I/R)... |
2,326,531 | Adaptive immune response to viral infections in the central nervous system. | Historically, the central nervous system (CNS) has been considered to be an immunologically privileged site within the body (Bailey et al., 2006; Galea et al. 2007; Engelhardt, 2008; Prendergast and Anderton, 2009). By definition, immunologically privileged sites, to include the brain, cornea, testis, and pregnant uter... |
2,326,532 | Pair bond formation is impaired by VPAC receptor antagonism in the socially monogamous zebra finch. | A variety of recent data demonstrate that vasoactive intestinal polypeptide (VIP) and VPAC receptors (which bind VIP, and to a lesser extent, pituitary adenylatecyclase activating peptide) are important for numerous social behaviors in songbirds, including grouping and aggression, although VIP relates to these behavior... |
2,326,533 | The influence of hypoxia during different pregnancy stages on cardiac collagen accumulation in the adult offspring. | We evaluated whether the timing of maternal hypoxia during pregnancy influenced cardiac extracellular matrix accumulation in the adult offspring. Rats in different periods of pregnancy were assigned to maternal hypoxia or control groups. Maternal hypoxia from day 3 to 21 of pregnancy or day 9 to 21 of pregnancy increas... |
2,326,534 | Evaluation of Protein Expression in Housekeeping Genes across Multiple Tissues in Rats. | Housekeeping genes, which show constant protein expression patterns between different tissue types, are very important in molecular biological studies as an internal control for protein research.</AbstractText>The protein expression profiles of seven housekeeping genes (HPRT1, PPIA, GYS1, TBP, YWHAZ, GAPDH and ACTB) in... |
2,326,535 | Current and emerging MR imaging techniques for the diagnosis and management of CSF flow disorders: a review of phase-contrast and time-spatial labeling inversion pulse. | This article provides an overview of phase-contrast and time-spatial labeling inversion pulse MR imaging techniques to assess CSF movement in the CNS under normal and pathophysiologic situations. Phase-contrast can quantitatively measure stroke volume in selected regions, notably the aqueduct of Sylvius, synchronized t... |
2,326,536 | Preoperative prognostic value of MRI findings in 108 patients with idiopathic normal pressure hydrocephalus. | MR imaging is used in the diagnostic evaluation of patients with idiopathic normal pressure hydrocephalus. The aim of this study was to describe the prevalence of several imaging features and their prognostic use in the selection of shunt candidates with idiopathic normal pressure hydrocephalus.</AbstractText>Preoperat... |
2,326,537 | Blockade of orexin type 1 receptors inhibits the development of morphine tolerance in lateral paragigantocellularis nucleus: an electrophysiological approach. | Repetitive administration of opioid agonists is associated with the development of tolerance to the effects of these substances and limits their application. Orexin (also known as hypocretin) is involved in morphine tolerance and dependence. The lateral paragigantocellularis nucleus (LPGi) is a key brain region implica... |
2,326,538 | RhoE deficiency alters postnatal subventricular zone development and the number of calbindin-expressing neurons in the olfactory bulb of mouse. | The subventricular zone represents an important reservoir of progenitor cells in the adult brain. Cells from the subventricular zone migrate along the rostral migratory stream and reach the olfactory bulb, where they originate different types of interneurons. In this work, we have analyzed the role of the small GTPase ... |
2,326,539 | Evaluation of variability of phase indices of the left ventricle in the course of time. | Since the effect of time on phase indices is still unclear, the aim of the study was to evaluate the variability of phase indices of the left ventricle which were derived from stress and rest single-photon emission computed tomography (SPECT) imaging acquired at early and late times.</AbstractText>One hundred twenty-on... |
2,326,540 | Influence of inhomogeneous static magnetic field-exposure on patients with erosive gastritis: a randomized, self- and placebo-controlled, double-blind, single centre, pilot study. | This pilot study was devoted to the effect of static magnetic field (SMF)-exposure on erosive gastritis. The randomized, self- and placebo-controlled, double-blind, pilot study included 16 patients of the 2nd Department of Internal Medicine, Semmelweis University diagnosed with erosive gastritis. The instrumental analy... |
2,326,541 | Involvement of Nrf2 in development of anxiety-like behavior by linking Bcl2 to oxidative phosphorylation: estimation in rat hippocampus, amygdala, and prefrontal cortex. | Anxiety-related disorders are complex illnesses that underlying molecular mechanisms of these complicated emotional disorders are poorly understood. Nuclear factor erythroid 2-related factor 2 (Nrf2) is the most important regulator of the antioxidant defense system. Its protective actions are not only limited to antiox... |
2,326,542 | MicroRNAs in right ventricular (dys)function (2013 Grover Conference series). | MicroRNAs (miRNAs) are molecules increasingly investigated for both diagnostic and therapeutic strategies. Whereas information about their role in the left ventricle has been studied for many years, there is scarce information about the right ventricle. We thus here review known details about the expression, regulation... |
2,326,543 | Right heart failure: toward a common language. | In this guideline, the International Right Heart Foundation Working Group moves a step forward to develop a common language to describe the development and defects that exemplify the common syndrome of right heart failure. We first propose fundamental definitions of the distinctive components of the right heart circula... |
2,326,544 | Meningoencephalitis in a dog due to Trichosporon montevideense. | Meningoencephalitis due to infection with Trichosporon montevideense was diagnosed in a 4-year-old dog with a brief clinical history of rapidly progressing neurological signs that culminated in a comatose state. No significant gross lesions were found at post-mortem examination. Microscopically, a few scattered areas o... |
2,326,545 | [Primary amenorrhoea and macrocephaly]. | Primary amenorrhoea has a broad differential diagnosis. When hypogonadotropic hypogonadism is present, possible intracranial abnormalities should always be suspected.</AbstractText>We present the case of a 16-year-old girl with primary amenorrhoea. Laboratory investigations showed hypogonadotropic hypogonadism. MRI of ... |
2,326,546 | Neurobiology: the eye within the brain. | All vertebrates except mammals have photoreceptors within their brains; however, the light-sensitive cells have never been unambiguously identified. A new paper provides direct evidence of photosensitivity in cerebrospinal fluid (CSF)-contacting neurons in quail brain that mediate the seasonal reproductive response. |
2,326,547 | Ventricular-vascular coupling in hypertension: methodological considerations and clinical implications. | The present review is addressed to analyse the complex interplay between left ventricle and arterial tree in hypertension. The different methodological approaches to the analysis of ventricular vascular coupling in the time and frequency domain are discussed. Moreover, the role of hypertension-related changes of arteri... |
2,326,548 | The transcription factor Fezf2 directs the differentiation of neural stem cells in the subventricular zone toward a cortical phenotype. | Postnatal neurogenesis in mammals is confined to restricted brain regions, including the subventricular zone (SVZ). In rodents, the SVZ is a lifelong source of new neurons fated to migrate to the olfactory bulb (OB), where the majority become GABAergic interneurons. The plastic capacity of neonatal and adult SVZ stem/p... |
2,326,549 | Mesencephalic astrocyte-derived neurotrophic factor prevents neuron loss via inhibiting ischemia-induced apoptosis. | Mesencephalic astrocyte-derived neurotrophic factor (MANF) has been shown to be up-regulated under the focal cerebral ischemia and protected against ischemic injury in rats. However, the underlying mechanisms are unclear. The aim of this study was to verify the protection of MANF on the cerebral ischemic injury and fur... |
2,326,550 | The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex. | Neural stem and progenitor cells have a central role in the development and evolution of the mammalian neocortex. In this review, we first provide a set of criteria to classify the various types of cortical stem and progenitor cells. We then discuss the issue of cell polarity, as well as specific subcellular features o... |
2,326,551 | Splenopancreatic ductal adenocarcinoma with multiorgan metastasis in a northern water snake (Nerodia sipedon). | A 16-yr-old northern water snake (Nerodia sipedon) presented with a large, firm midcoelomic swelling. A complete blood count, survey radiographs, coelomic ultrasound, and fine needle aspirate of the mass were performed. Survey radiographs revealed a soft tissue opacity mass. Ultrasonographic examination confirmed the p... |
2,326,552 | GATA-4 protects against hypoxia-induced cardiomyocyte injury: effects on mitochondrial membrane potential. | Our previous studies have suggested that GATA-4 increases the differentiation of bone-marrow-derived mesenchymal stem cells (MSCs) into cardiac phenotypes. This study further investigated whether GATA-4 enhances MSC-mediated cardioprotection following hypoxia. MSCs were harvested from rat bone marrow and transduced wit... |
2,326,553 | Microvascular circulation at cool, normal and warm temperatures in rat leg muscles examined by histochemistry using Lycopersicon esculentum lectin. | Local cooling and/or warming of the body are widely used for therapy. For safer and more effective therapy, microvascular hemodynamics needs to be clarified. To examine blood circulation in rat leg muscles at 20, 30, 37 and 40°C, fluorescein isothiocyanate (FITC)-labeled Lycopersicon esculentum lectin was injected... |
2,326,554 | Three-dimensional principal strain analysis for characterizing subclinical changes in left ventricular function.<Pagination><StartPage>1041</StartPage><EndPage>1050.e1</EndPage><MedlinePgn>1041-1050.e1</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.echo.2014.05.014</ELocationID><ELocationID E... | Myocarditis is an inflammation of the myocardium, but only -10% of those affected show clinical manifestations of the disease. To study the immune events of myocardial injuries, various mouse models of myocarditis have been widely used. This study involved experimental autoimmune myocarditis (EAM) induced with cardiac ... |
2,326,555 | Liver perfusion in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI): comparison of enhancement in Gd-BT-DO3A and Gd-EOB-DTPA in normal liver parenchyma. | Within-patient comparison of the enhancement patterns of normal liver parenchyma after gadobutrol and gadoxetate disodium, with emphasis on the start of hepatocytic uptake of gadoxetate disodium.</AbstractText>Twenty-one patients (12 female, 9 male) without chronic liver disease underwent 1.5-T contrast-enhanced MRI tw... |
2,326,556 | Changes in neural stem cells in the subventricular zone in a rat model of communicating hydrocephalus. | Communicating hydrocephalus is a common type of hydrocephalus. At present, the prevalent treatment is to perform a ventriculo-peritoneal shunt, which, for reasons that are not clear, is sometimes ineffective. The subventricular zone (SVZ) of the lateral ventricles has been established as the primary site of adult neuro... |
2,326,557 | Endoscopic third ventriculostomy and choroid plexus cauterization in infants with hydrocephalus: a retrospective Hydrocephalus Clinical Research Network study. | The use of endoscopic third ventriculostomy (ETV) with choroid plexus cauterization (CPC) has been advocated as an alternative to CSF shunting in infants with hydrocephalus. There are limited reports of this procedure in the North American population, however. The authors provide a retrospective review of the experienc... |
2,326,558 | Obliteration of the choroid plexus after endoscopic coagulation. | Endoscopic choroid plexus coagulation (CPC) with or without endoscopic third ventriculostomy (ETV) has been shown to be effective for selected patients with hydrocephalus. However, whether the effect of the coagulation is temporary and the choroid plexus regenerates or can be obliterated has remained largely unknown. T... |
2,326,559 | New endoscopic route to the temporal horn of the lateral ventricle: surgical simulation and morphometric assessment. | The temporal horn of the lateral ventricle is a complex structure affected by specific pathological conditions. Current approaches to the temporal horn involve a certain amount of corticotomy and white matter disruption. Surgeons therefore set aside anterior temporal lobectomy as a last resource and avoid it in the dom... |
2,326,560 | Comparison of two algorithms for the application of real-time image mosaicking in neuroendoscopy. | Neuroendoscopy is used more and more frequently in neurosurgical procedures and has become an important tool in the neurosurgical armamentarium. However, the main restriction of neuroendoscopy is the limited field of view. A better overview of the area of interest would increase surgical safety and decrease procedure-r... |
2,326,561 | Neuroepithelial cyst of the fourth ventricle. | Neuroepithelial cyst is considered an unusual differential diagnosis for cysts in the posterior fossa. Here, we present a paediatric case with such a pathology and review the pertinent literature.</AbstractText>A 12-year old girl with headache, vertigo and disturbed gait was diagnosed with a cystic lesion in the fourth... |
2,326,562 | An individual patient data meta-analysis on characteristics and outcome of patients with papillary glioneuronal tumor, rosette glioneuronal tumor with neuropil-like islands and rosette forming glioneuronal tumor of the fourth ventricle. | In 2007, the WHO classification of brain tumors was extended by three new entities of glioneuronal tumors: papillary glioneuronal tumor (PGNT), rosette-forming glioneuronal tumor of the fourth ventricle (RGNT) and glioneuronal tumor with neuropil-like islands (GNTNI). Focusing on clinical characteristics and outcome, t... |
2,326,563 | Restricted nature of adult neural stem cells: re-evaluation of their potential for brain repair. | Neural stem cells (NSCs) in the walls of the lateral ventricles continue to produce new neurons and oligodendrocytes throughout life. The identification of NSCs, long-range neuronal migration, and the integration of new neurons into fully formed mature neural circuits-all in the juvenile or adult brain-has dramatically... |
2,326,564 | The Hemi-Fontan operation: A critical overview. | The hemi-Fontan (HF) operation is a staging procedure in the journey towards an ultimate Fontan palliation. Although popular in the Western world, it has found limited application in the developing world. In this review we discuss the indications, techniques, merits, and demerits of this procedure along with its presen... |
2,326,565 | Synchronous rosette-forming glioneuronal tumor and diffuse astrocytoma with molecular characterization: a case report. | Rosette-forming glioneuronal tumor (WHO grade I) is a rare neoplasm primarily arising in young adults that is characterized by distinctive neurocytic rosette formation, a spindled glial component resembling pilocytic astrocytoma, and a high incidence of PIK3CA mutation. Low-grade diffuse astrocytoma (WHO grade II), on ... |
2,326,566 | Parametric-based brain Magnetic Resonance Elastography using a Rayleigh damping material model. | The three-parameter Rayleigh damping (RD) model applied to time-harmonic Magnetic Resonance Elastography (MRE) has potential to better characterise fluid-saturated tissue systems. However, it is not uniquely identifiable at a single frequency. One solution to this problem involves simultaneous inverse problem solution ... |
2,326,567 | Rosette-forming glioneuronal tumour (RGNT) of the fourth ventricle: a highly aggressive case. | The rosette-forming glioneuronal tumour (RGNT) is a rarely encountered tumour that has been included as a new entity in the 2007 edition of the "World Health Organization (WHO) Classification of Tumours of the Central Nervous System". We describe a rather unusual case of multifocal cerebellar RGNT, located in the spina... |
2,326,568 | Minimally invasive cone beam CT-guided evacuation of parenchymal and ventricular hemorrhage using the Apollo system: proof of concept in a cadaver model. | The Apollo system (Penumbra Inc, Alameda, California, USA) is a low profile irrigation-aspiration system designed for the evacuation of intracranial hemorrhage.</AbstractText>To demonstrate the feasibility of using Apollo in combination with cone beam CT guidance.</AbstractText>Parenchymal (n=1) and mixed parenchymal-i... |
2,326,569 | Thrombospondin 4 deficiency in mouse impairs neuronal migration in the early postnatal and adult brain. | In the post-natal rodent brain, neuronal precursors originating from the sub-ventricular zone (SVZ) migrate over a long distance along the rostral migratory stream (RMS) to eventually integrate the olfactory bulb neuronal circuitry. In order to identify new genes specifically expressed in the RMS, we have screened the ... |
2,326,570 | A framework for the merging of pre-existing and correspondenceless 3D statistical shape models. | The construction of statistical shape models (SSMs) that are rich, i.e., that represent well the natural and complex variability of anatomical structures, is an important research topic in medical imaging. To this end, existing works have addressed the limited availability of training data by decomposing the shape vari... |
2,326,571 | New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis. | The subventricular zone (SVZ) contains neural stem cells (NSCs) that generate new neurons throughout life. Many brain diseases stimulate NSCs proliferation, neuronal differentiation and homing of these newborns cells into damaged regions. However, complete cell replacement has never been fully achieved. Hence, the iden... |
2,326,572 | Trajectories of heart failure self-care management and changes in quality of life. | Heart failure patients vary considerably in their self-care management behaviors (i.e. recognizing and responding to symptoms). The goal of this study was to identify unique patterns of change in heart failure self-care management and quantify associations between self-care management and quality of life (HRQOL) over t... |
2,326,573 | Targeted gene transfer into ependymal cells through intraventricular injection of AAV1 vector and long-term enzyme replacement via the CSF. | Enzyme replacement via the cerebrospinal fluid (CSF) has been shown to ameliorate neurological symptoms in model animals with neuropathic metabolic disorders. Gene therapy via the CSF offers a means to achieve a long-term sustainable supply of therapeutic proteins within the central nervous system (CNS) by setting up a... |
2,326,574 | Cardicola beveridgei n. sp. (Digenea: Aporocotylidae) from the mangrove jack, Lutjanus argentimaculatus (Perciformes: Lutjanidae), and C. bullardi n. sp. from the Australian spotted mackerel, Scomberomorus munroi (Perciformes: Scombridae), from the northern Great Barrier Reef. | Cardicola Short, 1953 is a genus of the Aporocotylidae Odhner, 1912 (Digenea), with 25 currently recognised species described from 32 species of Perciformes and Mugiliformes fishes around the world, including eight species from the Great Barrier Reef. Here, we describe two new species from this region, namely Cardicola... |
2,326,575 | Impact of adiposity on cardiac structure in adult life: the Childhood Determinants of Adult Health (CDAH) study. | We have examined the association between adiposity and cardiac structure in adulthood, using a life course approach that takes account of the contribution of adiposity in both childhood and adulthood.</AbstractText>The Childhood Determinants of Adult Health study (CDAH) is a follow-up study of 8,498 children who partic... |
2,326,576 | [Successful tracheal intubation using the GlideScope AVL in a pediatric patient with Pierre Robin syndrome]. | We report a successful use of GlideScope AVL in a pediatric patient with Pierre Robin syndrome. A 36-day-old boy weighing 2.8 kg with Pierre Robin syndrome presented for tracheostomy after several weeks of trial airway management in prone position, who had failed to relieve his obstructive apnea. The Pentax-AWS videola... |
2,326,577 | Chronic Stress and Early Recurrence of Takotsubo Cardiomyopathy: A Clinical Case. | Takotsubo cardiomyopathy (TC) is characterized by transient systolic dysfunction of the apical and middle segments of the left ventricle, accompanied by electrocardiographic abnormalities and mild elevation of cardiac biomarker levels in the absence of obstructive coronary artery disease. The following case is of a wom... |
2,326,578 | New concepts in the pathogenesis of hydrocephalus. | Hydrocephalus is a central nervous system disorder characterized by excessive accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain. Cognitive and physical handicap can occur as a result of hydrocephalus. The disorder can present at any age as a result of a wide variety of different diseases. The pat... |
2,326,579 | Progressive multifocal leukoencephalopathy: a rare cause of cerebellar edema and atypical mass effect. A case report. | Progressive multifocal leukoencephalopathy (PML) is an opportunistic demyelinating disease of the CNS caused by the JC papovavirus (JCV). Demyelination due to oligodendrocyte death leads to multifocal, asymmetric lesions. MRI is a valuable tool for detecting and differentiating PML from other neuropathies. Radiographic... |
2,326,580 | Assessment of cerebrospinal fluid flow patterns using the time-spatial labeling inversion pulse technique with 3T MRI: early clinical experiences. | CSF imaging using the time-spatial labeling inversion pulse (time-SLIP) technique at 3T magnetic resonance imaging (MRI) was performed to assess cerebrospinal fluid (CSF) dynamics. The study population comprised 15 healthy volunteers and five patients with MR findings showing expansive dilation of the third and lateral... |
2,326,581 | Left ventricular myocardial strain by three-dimensional speckle-tracking echocardiography in healthy subjects: reference values and analysis of their physiologic and technical determinants. | Despite growing interest in applying three-dimensional (3D) speckle-tracking echocardiography (STE) to measure left ventricular (LV) myocardial deformation in various diseases, normative values for 3D speckle-tracking echocardiographic parameters and the effects of demographic, hemodynamic, and technical factors on the... |
2,326,582 | Rescue extracorporeal membrane oxygenation in a young man with a stab wound in the chest. | A 27-year-old man with haemorrhagic shock and acute cardiac tamponade due to a stab in the chest underwent successful resuscitation and surgical repair of the right ventricular perforation thanks to the use of extracorporeal membrane oxygenation (ECMO) in the emergency department. To the best of the authors' knowledge,... |
2,326,583 | Anatomo-functional study of the temporo-parieto-occipital region: dissection, tractographic and brain mapping evidence from a neurosurgical perspective. | The temporo-parieto-occipital (TPO) junction is a complex brain territory heavily involved in several high-level neurological functions, such as language, visuo-spatial recognition, writing, reading, symbol processing, calculation, self-processing, working memory, musical memory, and face and object recognition. Recent... |
2,326,584 | Is pineal melatonin released in the third ventricle in humans? A study in movement disorders. | In order to determine sources and metabolism of melatonin in human cerebrospinal fluid (CSF), melatonin and 6-sulfatoxymelatonin (aMT6S) concentrations were measured in CSF sampled during neurosurgery in both lateral and third ventricles in patients displaying movement disorder (Parkinson's disease, essential tremor, d... |
2,326,585 | Schisandrin A and B affect subventricular zone neurogenesis in mouse. | Schisandrin A and B (Sch A and B) are the main effective components extracted from the oriental medicine Schisandra chinensis which is traditionally used to enhance mental and intellectual function. Although their neuroprotective effects have been demonstrated, their influences on neurogenesis are still unknown. In the... |
2,326,586 | Sellar cysticercosis and septum pellucidum cyst: a case report and review of the literature. | Sellar cysticercosis is a rare form of neurocysticercosis. A septum pellucidum cysts is a rare, often asymptomatic cystic structure between the lateral ventricles. We report here a male patient with sellar cysticercosis and septum pellucidum cysts who was successfully treated by neuroendoscopic resection. The patient w... |
2,326,587 | Anatomical, molecular and pathological consideration of the circumventricular organs. | Circumventricular organs (CVOs) are a diverse group of specialised structures characterized by peculiar vascular and position around the third and fourth ventricles of the brain. In humans, these organs are present during the fetal period and some become vestigial after birth. Some, such as the pineal gland (PG), subco... |
2,326,588 | Personalising population-based respiratory motion models of the heart using neighbourhood approximation based on learnt anatomical features. | Respiratory motion models have been proposed for the estimation and compensation of respiratory motion during image acquisition and image-guided interventions on organs in the chest and abdomen. However, such techniques are not commonly used in the clinic. Subject-specific motion models require a dynamic calibration sc... |
2,326,589 | Association between gait variability and brain ventricle attributes: a brain mapping study. | It remains unknown which brain regions are involved in the maintenance of gait dynamic stability in older adults, as characterized by a low stride time variability. Expansion of lateral cerebral ventricles is an indirect marker of adjacent brain tissue volume. The purpose of this study was to examine the association be... |
2,326,590 | Effect of Ca2+ efflux pathway distribution and exogenous Ca2+ buffers on intracellular Ca2+ dynamics in the rat ventricular myocyte: a simulation study. | We have used a previously published computer model of the rat cardiac ventricular myocyte to investigate the effect of changing the distribution of Ca(2+) efflux pathways (SERCA, Na(+)/Ca(2+) exchange, and sarcolemmal Ca(2+) ATPase) between the dyad and bulk cytoplasm and the effect of adding exogenous Ca(2+) buffers (... |
2,326,591 | Impact of obstructive sleep apnea and snoring on left ventricular mass and diastolic function in hypertensive nigerians. | Systemic hypertension (HTN) and obstructive sleep apnea (OSA) are individually associated with left ventricular structural and functional adaptations. However, little is known about the impact of OSA on the left ventricle in Africans with HTN.</AbstractText>The aim of this study is to determine the association between ... |
2,326,592 | Maternal undernutrition around the time of conception and embryo number each impact on the abundance of key regulators of cardiac growth and metabolism in the fetal sheep heart. | Poor maternal nutrition before and during pregnancy is associated with an increased risk of cardiovascular disease in later life. To determine the impact of maternal undernutrition during the periconceptional (PCUN: -45 days to 6 days) and preimplantation (PIUN: 0-6 days) periods on cardiac growth and metabolism, we ha... |
2,326,593 | Interleukin-13 deficiency aggravates healing and remodeling in male mice after experimental myocardial infarction. | Activation of innate immunity, especially infiltration of monocytes, is critical for proper wound healing and scar formation after myocardial infarction (MI). Therefore, we tested the hypothesis that interleukin-13 (IL-13), which influences the differentiation of monocytes/macrophages and has profibrotic properties, mo... |
2,326,594 | Atypical Bourneville sclerosis without epilepsy and mental retardation: case report and literature review. | Twenty-four-year-old woman without familiar detected signs of Bourneville's disease or tuberous sclerosis complex (TSC) was diagnosed with this disease by casual discovery on cerebral magnetic resonance imaging (MRI) of an intraventricular tumor, after symptoms consist in headache, equilibrium disturbances, and progres... |
2,326,595 | Impaired functional communication between the L-type calcium channel and mitochondria contributes to metabolic inhibition in the mdx heart. | Duchenne muscular dystrophy is a fatal X-linked disease characterized by the absence of dystrophin. Approximately 20% of boys will die of dilated cardiomyopathy that is associated with cytoskeletal protein disarray, contractile dysfunction, and reduced energy production. However, the mechanisms for altered energy metab... |
2,326,596 | Heart ventricles specific stress-induced changes in β-adrenoceptors and muscarinic receptors. | The left and right ventricles fulfill different role in heart function. Here we compare chamber specific changes in local catecholamine concentrations; gene expression and the receptor protein amount of all three β-adrenoceptors (β-AR) in rat right heart ventricles exposed to acute (1 session) and repeated ... |
2,326,597 | A case of intraventricular primary central nervous system lymphoma. | We report a case of primary central nervous system lymphoma presenting as multiple intraventricular masses in an immunocompetent 68 year old man with severe headache and unsteady gait. The diagnosis was obtained by analysis of the cerebrospinal fluid and subsequent surgical biopsy. This is an unusual appearance for pri... |
2,326,598 | Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation. | Growth differentiation factor 10 (Gdf10), also known as Bmp3b, is a member of the transforming growth factor (TGF)-ß superfamily. Gdf10 is expressed in Bergmann glial cells, which was investigated by single-cell transcriptional profiling (Koirala and Corfas, (2010) PLoS ONE 5: e9198). Here we provide a detailed ch... |
2,326,599 | Maternal pravastatin prevents altered fetal brain development in a preeclamptic CD-1 mouse model. | Using an animal model, we have previously shown that preeclampsia results in long-term adverse neuromotor outcomes in the offspring, and this phenotype was prevented by antenatal treatment with pravastatin. This study aims to localize the altered neuromotor programming in this animal model and to evaluate the role of p... |
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