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2,326,600 | Neurocysticercosis presenting as focal hydrocephalus. | A 40-year-old man presented with a 2-month history of headache, nausea and vomiting, with generalised seizures for the past 15 days. On examination he had bilateral papilloedema, visual acuity was 6/6 in both eyes but perimetry showed right homonymous inferior quadrantanopia. His MRI showed numerous small cystic... |
2,326,601 | TNFα causes thrombin-dependent vagal neuron apoptosis in inflammatory bowel disease. | The role of peripheral tumor necrosis factor alpha (TNFα) in inflammatory bowel disease (IBD) is well established, but its central nervous system (CNS) effects are not understood. Thrombin, another mediator of inflammation in IBD, has been implicated in CNS vagal neuron apoptosis in the dorsal motor nucleus of th... |
2,326,602 | Hybrid technology in treatment of severe combined pathology.<Pagination><StartPage>158</StartPage><EndPage>166</EndPage><MedlinePgn>158-66</MedlinePgn></Pagination><Abstract><AbstractText>The present report describes a clinical case concerning a two-stage hybrid operative intervention in a patient presenting with an ao... | The present report describes a clinical case concerning a two-stage hybrid operative intervention in a patient presenting with an aortic arch aneurysm associated with coronary artery disease. The first stage consisted in performing mammary coronary artery bypass grafting of the anterior descending artery, coronary arte... |
2,326,603 | The clinical benefits of adding a third dimension to assess the left ventricle with echocardiography. | Three-dimensional echocardiography is a novel imaging technique based on acquisition and display of volumetric data sets in the beating heart. This permits a comprehensive evaluation of left ventricular (LV) anatomy and function from a single acquisition and expands the diagnostic possibilities of noninvasive cardiolog... |
2,326,604 | Association of myeloid cells of triggering receptor-1 with left ventricular systolic dysfunction in BALB/c mice with sepsis. | To investigate the correlation between TREM-1 and LPS-induced left ventricular systolic dysfunction in BALB/c mice.</AbstractText>Male BALB/c mice were randomly divided into 3 groups: LPS, LPS/TREM-1, and control groups which were injected intraperitoneally with 25 mg/kg LPS, 5 μg TREM-1mAb 1 h after LPS challeng... |
2,326,605 | Measuring myofiber orientations from high-frequency ultrasound images using multiscale decompositions. | High-frequency ultrasound (HFU) has the ability to image both skeletal and cardiac muscles. The quantitative assessment of these myofiber orientations has a number of applications in both research and clinical examinations; however, difficulties arise due to the severe speckle noise contained in the HFU images. Thus, f... |
2,326,606 | Dynamic oxygen-enhanced MRI of cerebrospinal fluid. | Oxygen causes an increase in the longitudinal relaxation rate of tissues through its T1-shortening effect owing to its paramagnetic properties. Due to such effects, MRI has been used to study oxygen-related signal intensity changes in various body parts including cerebrospinal fluid (CSF) space. Oxygen enhancement of C... |
2,326,607 | Effects of aerobic training, resistance training, or combined resistance-aerobic training on the left ventricular myocardium in a rat model. | This study follows the left ventricular (LV) hypertrophy in rats undergoing aerobic training alone (A), resistance training alone (R), or combined resistance and aerobic training (RA) (usually referred as concurrent training) program. A sedentary control group (C) was included. LV remodeling was evaluated using electro... |
2,326,608 | Endoscopic versus microsurgical resection of colloid cysts: a systematic review and meta-analysis of 1,278 patients. | Colloid cysts of the third ventricle have been successfully treated with transcranial microsurgical approaches. However, the endoscopic approach has recently been advocated as a lesser invasive technique. We conducted a systematic review and meta-analysis of published studies to compare the outcomes between the two app... |
2,326,609 | Axial diffusivity of the corona radiata correlated with ventricular size in adult hydrocephalus. | Hydrocephalus causes changes in the diffusion-tensor properties of periventricular white matter. Understanding the nature of these changes may aid in the diagnosis and treatment planning of this relatively common neurologic condition. Because ventricular size is a common measure of the severity of hydrocephalus, we hyp... |
2,326,610 | Poor correlation between head circumference and cranial ultrasound findings in premature infants with intraventricular hemorrhage. | Intraventricular hemorrhage (IVH) is the most common cause of hydrocephalus in the pediatric population and is particularly common in preterm infants. The decision to place a ventriculoperitoneal shunt or ventricular access device is based on physical examination findings and radiographic imaging. The authors undertook... |
2,326,611 | The PVH as a site of CB1-mediated stimulation of thermogenesis by MC4R agonism in male rats. | The present study was designed to investigate the involvement of the cannabinoid receptor 1 (CB1) in the stimulating effects of the melanocortin-4 receptor (MC4R) agonism on whole-body and brown adipose tissue (BAT) thermogenesis. In a first series of experiments, whole-body and BAT thermogenesis were investigated in r... |
2,326,612 | Imaging mass spectrometry of diversified cardiolipin molecular species in the brain. | MALDI imaging mass spectrometry (MALDI-IMS) has been used successfully in mapping different lipids in tissue sections, yet existing protocols fail to detect the diverse species of mitochondria-unique cardiolipins (CLs) in the brain which are essential for cellular and mitochondrial physiology. We have developed methods... |
2,326,613 | [The 2013 Sixto Obrador Award. A triple-axis topographical model for surgical planning of craniopharyngiomas. Part II: Anatomical and neuroradiological evidence to define triple-axis topography and its usefulness in predicting individual surgical risk]. | This study evaluates the pathological and magnetic resonance imaging evidence to define the precise topographical relationships of craniopharyngiomas and to classify these lesions according to the risks of hypothalamic injury associated with their removal.</AbstractText>An extensive, systematic analysis of the topograp... |
2,326,614 | Epigenetic regulation by chromatin activation mark H3K4me3 in primate progenitor cells within adult neurogenic niche. | Histone 3 lysine 4 trimethylation (H3K4me3) is known to be associated with transcriptionally active or poised genes and required for postnatal neurogenesis within the subventricular zone (SVZ) in the rodent model. Previous comparisons have shown significant correlation between baboon (Papio anubis) and human brain. In ... |
2,326,615 | In vitro evaluation of ice-cold saline irrigation during catheter radiofrequency ablation. | Irrigated radiofrequency (RF) catheters allow tissue-electrode interface cooling, decreasing thrombus risk while enabling higher RF power delivery. The impact of irrigation with ice-cold saline (ICS) instead of conventional ambient-temperature saline (ATS) on lesion formation is unknown.</AbstractText>We performed 120 ... |
2,326,616 | Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in rats. | Inflammation plays a key role in the pathophysiology of ischemic stroke. Some proinflammatory mediators, such as cytokines and chemokines, are produced in stroke. Chemokine-like factor 1 (CKLF1), as a novel C-C chemokine, displays chemotactic activities in a wide spectrum of leukocytes and plays an important role in br... |
2,326,617 | AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease. | Huntington's disease (HD) is an autosomal dominant neurological disorder that is induced by a CAG trinucleotide expansion in exon 1 of the Huntingtin (HTT) gene. We previously reported that the abnormal activation of an important energy sensor, AMP-activated protein kinase α1 (AMPK-α1), occurs in the brains... |
2,326,618 | Slit ventricle syndrome and early-onset secondary craniosynostosis in an infant. | Female, 14 months</AbstractText>Slit ventricle syndrome Symptoms: Hydrocephalus • lethargy and seizure • vomiting</AbstractText>- Clinical Procedure: - Specialty: Pediatrics and Neonatology.</AbstractText>Challenging differential diagnosis.</AbstractText>Shunt surgery is a common solution for hydrocephalu... |
2,326,619 | Effect of ligustilide on Ang II-induced hypertrophy in cardiomyocytes and the potential mechanisms. | The aim of the present study was to investigate the effect of ligustilide (LIG) on angiotensin II (Ang II)-induced hypertrophy in neonatal rat myocardial cells and the expression levels of p53, Bcl-2 and Bax. Myocardial cells were isolated and purified from the ventricles of neonate Sprague-Dawley rats (age, 1-3 days) ... |
2,326,620 | Large cell/anaplastic medulloblastoma with myogenic, melanotic and neuronal differentiation: a case report of a rare tumor. | Medulloblastoma is an embryonal neuroepithelial tumor of the cerebellum and is the most common malignant central nervous system tumor in children. Different histological variants and patterns have been described. The classic variant represents the majority of cases. This report describes a rare case of large cell/anapl... |
2,326,621 | Lateral ventricular cystic meningioma: 2 rare case reports. | Cystic meningioma is an uncommon meningioma variant that is often difficult to distinguish from other intra-axial tumors, including necrotic gliomas. Cystic meningiomas located in the ventricle are particularly rare and may be misdiagnosed with other brain tumors, including ependymoma, choroid plexus papilloma and neur... |
2,326,622 | Following OGD/R, annexin 1 nuclear translocation and subsequent induction of apoptosis in neurons are assisted by myosin IIA in a TRPM7 kinase-dependent manner. | Transient receptor potential cation channel, subfamily M, member 7 (TRPM7) is a bifunctional channel protein that contains an α-kinase domain at its C-terminal. Previous studies have indicated that oxygen-glucose deprivation/reoxygenation (OGD/R) induces neuronal apoptosis via TRPM7. Annexin 1 and myosin IIA have... |
2,326,623 | Individually adapted tube current selection and contrast medium injection protocol of coronary CT angiography based on test bolus parameters: a feasibility study. | Test bolus is mostly used to determine the starting point of a full cardiac scanning with respect to injection of a larger bolus of contrast material. So far there are limited data demonstrating the feasibility of using information obtained from a test bolus to adjust contrast delivery protocols and tube current indivi... |
2,326,624 | Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review. | Clinically, central nervous system (CNS) disorders account for more hospitalisations and prolonged care than almost all other diseases combined. In the preclinical setting, the intracerebroventricular (ICV) route for cerebrospinal fluid (CSF) sampling or dose administration in rodent models of human CNS disorders has p... |
2,326,625 | High-salt intake suppressed microRNA-133a expression in Dahl SS rat myocardium. | Salt-sensitive individuals show earlier and more serious cardiac damage than nonsalt-sensitive ones. Some studies have suggested that microRNA-133a could reduce cardiac hypertrophy and myocardial fibrosis. The current study aims to investigate the different functions of high-salt intake on salt-sensitive (SS) rats and ... |
2,326,626 | Intraventricular craniopharyngiomas: surgical management and outcome analyses in 24 cases. | Pure intraventricular craniopharyngioma is a rare subtype of craniopharyngioma that attaches frequently to the hypothalamus. The main challenge in tumor removal is protection of hypothalamic structure. The aim of our study was to set up a feasible risk-evaluation approach to help the surgeons make an individual treatme... |
2,326,627 | Clinical factors predicting outcomes after surgical resection for sporadic cerebellar hemangioblastomas. | To determine whether various clinical factors are related to long-term outcomes of patients with sporadic cerebellar hemangioblastomas.</AbstractText>Subjects included 36 patients (19 men and 17 women) who underwent resection of sporadic hemangioblastoma in the cerebellum. Age at surgery ranged from 17-79 years (mean, ... |
2,326,628 | A template-based procedure for determining white matter integrity in the internal capsule early after stroke. | The integrity of descending white matter pathways, measured by fractional anisotropy from DW-MRI, is a key prognostic indicator of motor recovery after stroke. Barriers to translation of fractional anisotropy measures into routine clinical practice include the time required for manually delineating volumes of interest ... |
2,326,629 | Deferoxamine attenuates acute hydrocephalus after traumatic brain injury in rats. | Acute post-traumatic ventricular dilation and hydrocephalus are relatively frequent consequences of traumatic brain injury (TBI). Several recent studies have indicated that high iron levels in brain may relate to hydrocephalus development after intracranial hemorrhage. However, the role of iron in the development of po... |
2,326,630 | Liver X receptor β is essential for the differentiation of radial glial cells to oligodendrocytes in the dorsal cortex. | Several psychiatric disorders are associated with aberrant white matter development, suggesting oligodendrocyte and myelin dysfunction in these diseases. There are indications that radial glial cells (RGCs) are involved in initiating myelination, and may contribute to the production of oligodendrocyte progenitor cells ... |
2,326,631 | Fluorescent protein-expressing neural progenitor cells as a tool for transplantation studies. | The purpose of this study was to generate quadruple fluorescent protein (QFP) transgenic mice as a source for QFP-expressing neural stem and progenitor cells (NSCs/NPCs) that could be utilized as a tool for transplantation research. When undifferentiated, these NSCs only express cyan fluorescent protein (CFP); however,... |
2,326,632 | Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats. | Many aspects of CSF dynamics are poorly understood due to the difficulties involved in quantification and visualization. In particular, there is debate surrounding the route of CSF drainage. Our aim was to quantify CSF flow, volume, and drainage route dynamics in vivo in young and aged spontaneously hypertensive rats (... |
2,326,633 | Cytoarchitecture of the olfactory bulb in the laggard mutant mouse. | The laggard (lag) mutant mouse, characterized by hypomyelination and cerebellar ataxia, is a spontaneously occurring mutant mouse caused by mutation in the Kif14 gene. In this mutant mouse, the laminated structures such as the cerebral and cerebellar cortices and the dentate gyrus are cytoarchitecturally abnormal. Macr... |
2,326,634 | Neuropsychological performance, brain imaging, and driving violations in multiple sclerosis. | To examine the relationship between third ventricular width, a measure of thalamic brain atrophy, and motor vehicle violation type and frequency in a cohort of patients with multiple sclerosis (MS).</AbstractText>Retrospective cohort study.</AbstractText>Tertiary care university hospital.</AbstractText>Thirty-five indi... |
2,326,635 | Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain. | The individual contribution of different progenitor subtypes towards the mature rodent cerebral cortex is not fully understood. Intermediate progenitor cells (IPCs) are key to understanding the regulation of neuronal number during cortical development and evolution, yet their exact contribution is much debated. Interme... |
2,326,636 | Establishment of NOD/SCID mouse model of central nervous system leukemia. | In the present study, we successfully established a NOD/SCID mouse model of central nervous system leukemia by injection of acute monocytic leukemia cell line SHI-1 cells into the lateral ventricle. Immunohistochemistry was used to detect human leukocyte common antigen in brain slices. Nested PCR assay was used to dete... |
2,326,637 | Factors associated with ventricular catheter movement and inaccurate catheter location: post hoc analysis of the hydrocephalus clinical research network ultrasound-guided shunt placement study. | Shunt survival may improve when ventricular catheters are placed into the frontal horn or trigone of the lateral ventricle. However, techniques for accurate catheter placement have not been developed. The authors recently reported a prospective study designed to test the accuracy of catheter placement with the assistan... |
2,326,638 | Primary malignant peripheral nerve sheath tumor of the spine with acute hydrocephalus: a rare clinical entity. | Primary malignant peripheral nerve sheath tumors (MPNSTs) are extremely rare in patients without a history of neurofibromatosis; only 18 cases have been reported in the English-language literature to this point. The authors report their experience with 1 new case of a primary MPNST. A 33-year-old woman presented with l... |
2,326,639 | Endoscopic approach to colloid cyst: what is the optimal entry point and trajectory? | An optimal entry point and trajectory for endoscopic colloid cyst (ECC) resection helps to protect important neurovascular structures. There is a large discrepancy in the entry point and trajectory in the neuroendoscopic literature.</AbstractText>Trajectory views from MRI or CT scans used for cranial image guidance in ... |
2,326,640 | Diffusion-weighted imaging thermometry in multiple sclerosis. | To prospectively investigate brain temperature using MR diffusion-weighted imaging thermometry in multiple sclerosis (MS) patients and age-matched healthy controls, to examine comparisons of brain temperature between MS patients and healthy volunteers, and to examine correlations between brain temperature and disease d... |
2,326,641 | White matter segmentation based on a skeletonized atlas: effects on diffusion tensor imaging studies of regions of interest. | To compare the influence of conventional and skeletonized atlas-based white matter (WM) segmentation on diffusion tensor imaging (DTI) region-of-interest (ROI) investigations.</AbstractText>A conventional WM atlas was skeletonized by thinning the corresponding fractional anisotropy (FA) map and labels. The conventional... |
2,326,642 | CXCR-7 receptor promotes SDF-1α-induced migration of bone marrow mesenchymal stem cells in the transient cerebral ischemia/reperfusion rat hippocampus. | The stromal cell-derived factor 1/C-X-C chemokine receptor type 4 (SDF-1/CXCR-4) axis plays an important role during stem cell recruitment. SDF-1 can also bind the more recently described CXCR-7 receptor, but effects of SDF-1/CXCR-7 signaling on stem cell migrating to ischemic brain injury area are little known. In the... |
2,326,643 | Increased collagen deposition in the heart of chronically hypoxic ovine fetuses. | This study determined the effect of chronic intrauterine hypoxia on collagen deposition in the fetal sheep heart. Moderate or severe hypoxia was induced by placental embolization in chronically catheterized fetal sheep for 15 days starting at gestational day 116 ± 2 (term ∼147 days). The fetal right and lef... |
2,326,644 | Factors affecting surgical outcome of endoscopic third ventriculostomy in congenital hydrocephalus. | Endoscopic third ventriculostomy (ETV) is an accepted modality of treatment for obstructive hydrocephalus, with good results in adult patients. However in the pediatric age group results vary from poor to similar to the adult population. This study evaluates the outcome of ETV in congenital hydrocephalus of both early ... |
2,326,645 | Cardiovascular magnetic resonance validation of fractional changes in annulo-apical angles and tricuspid annular plane systolic excursion for rapid assessment of right ventricular systolic function.<Pagination><StartPage>133</StartPage><EndPage>139</EndPage><MedlinePgn>133-9</MedlinePgn></Pagination><ELocationID EIdTyp... | Results of performance of Senning operation for the main vessels transposition were analyzed. Analysis of complications, lethality in early postoperative period and of far-remote results was conducted. The systemic right ventricle function in patients after Senning operation was estimated. Not high level of early and l... |
2,326,646 | Left ventricular strain and its pattern estimated from cine CMR and validation with DENSE. | Measurement of local strain provides insight into the biomechanical significance of viable myocardium. We attempted to estimate myocardial strain from cine cardiovascular magnetic resonance (CMR) images by using a b-spline deformable image registration method. Three healthy volunteers and 41 patients with either recent... |
2,326,647 | Left and Right Ventricle Leads Switch as a Solution for TWave Oversensing - How a Good Idea Turned Out Bad. | A 50-year-old male with a CRT defibrillator received inappropriate ICD shocks due to T-wave oversensing. Decreasing the sensitivity to avoid T wave oversensing was not an option due to a suboptimal R-wave sensing amplitude. We decided to re-plug the LV lead in the RV port and the RV lead in the LV port. This however le... |
2,326,648 | [A case of lateral ventricle metastasis from gastric carcinoma]. | Metastatic brain tumors of the lateral ventricles are rare. Approximately half of the reported cases have originated from renal carcinoma;to the best of our knowledge, only 1 case originating from gastric carcinoma has been reported. A 57-year-old man presented with dull headache, left hemiparesis, and constructional a... |
2,326,649 | Cardiac extracellular proteome profiling and membrane topology analysis using glycoproteomics. | Extracellular proteins are easily accessible, which presents a subproteome of molecular targets that have high diagnostic and therapeutic potential. Efforts have been made to catalog the cardiac extracellular matridome and analyze the topology of identified proteins for the design of therapeutic targets. Although many ... |
2,326,650 | Long-term MRI cell tracking after intraventricular delivery in a patient with global cerebral ischemia and prospects for magnetic navigation of stem cells within the CSF. | The purpose of the study was to evaluate the long-term clinical tracking of magnetically labeled stem cells after intracerebroventricular transplantation as well as to investigate in vitro feasibility for magnetic guidance of cell therapy within large fluid compartments.</AbstractText>After approval by our Institutiona... |
2,326,651 | Microsurgical training model with nonliving swine head. Alternative for neurosurgical education. | This paper proposes a practical model of microneurosurgical training using a nonliving swine head.</AbstractText>Fresh porcine heads were obtained from butchery and dissected at our Laboratory of Microsurgery. Brain and skull base surgery were trained under microscopic magnification.</AbstractText>Several neurosurgical... |
2,326,652 | [Stress (Takotsubo) cardiomyopathy in a patient with anorexia nervosa]. | We report the case of a woman with anorexia nervosa who developed takotsubo cardiomyopathy triggered by emotional stress and electrolyte disturbances. The patient improved with conservative management. Descriptions of stress-cardiomyopathy in association with eating disorders are often of higher severity and related to... |
2,326,653 | D609-mediated inhibition of ATP synthesis in neural progenitor cells. | Tricyclodecan-9-yl-xanthogenate (D609) is an antioxidative molecule with antiproliferative and neuroprotective properties in a variety of cells. Previously, we have shown that D609 decreased the proliferation of neural progenitor cells. In this study, we examined the antioxidative property of D609 on neural progenitor ... |
2,326,654 | Comparison of rapid cranial MRI to CT for ventricular shunt malfunction. | To compare the accuracy of rapid cranial magnetic resonance imaging (MRI) with that of computed tomography (CT) for diagnosing ventricular shunt malfunction.</AbstractText>We performed a single-center, retrospective cohort study of children ≤21 years of age who underwent either rapid cranial MRI or cranial CT in... |
2,326,655 | [Penetrating injury of the left ventricle caused by a nail gun; report of a case]. | Penetrating cardiac injuries are life-threatening emergencies. We present a case of a 24-year-old construction worker who accidentally shot himself with a nail gun. Chest X-ray showed a 6 cm-long nail overlapping the cardiac shadow. A computed tomography (CT) scan revealed the nail penetrating the left ventricle and a ... |
2,326,656 | Neonatal influenza infection causes pathological changes in the mouse brain. | Influenza A virus infections have been proposed to be associated with a broad spectrum of central nervous system complications that range from acute encephalitis/encephalopathy to neuropsychiatric disorders in humans. In order to study early influenza virus exposure in the brain, we created an influenza-infection model... |
2,326,657 | New pitfalls of high-density postmortem computed tomography. | An 80-year-old female was transferred to the hospital due to a traffic accident. Multiple cranial bone fractures with intracranial hemorrhage and intracranial air were detected. Despite treatment, the patient died after 6h. Twenty-one hours after the patient died, her whole body was scanned by postmortem CT, and a regi... |
2,326,658 | Thrombin mediates vagal apoptosis and dysfunction in inflammatory bowel disease. | In inflammatory bowel disease, autonomic dysfunction contributes to symptoms, morbidity, and health care resource utilization. Efferent vagal neurons, which provide the primary parasympathetic input to the gastrointestinal tract, are housed in the dorsal motor nucleus of the vagus (DMV) in the brainstem. This study see... |
2,326,659 | Cervical vestibular evoked myogenic potentials in cerebellar lesions. | Reports about cervical vestibular evoked myogenic potentials (cVEMPs) in central nervous system lesions are scarce. Our experience with cerebellar lesions is still evolving, with only a few cases published. The purpose of this article is to present our cVEMP findings of 3 cases with cerebellar lesions.</AbstractText>cV... |
2,326,660 | Dietary salt intake exaggerates sympathetic reflexes and increases blood pressure variability in normotensive rats. | Previous studies have reported that chronic increases in dietary salt intake enhance sympathetic nerve activity and arterial blood pressure (ABP) responses evoked from brain stem nuclei of normotensive, salt-resistant rats. The purpose of the present study was to determine whether this sensitization results in exaggera... |
2,326,661 | CXCR4/CXCR7 molecular involvement in neuronal and neural progenitor migration: focus in CNS repair. | In the adult brain, neural progenitor cells (NPCs) reside in the subventricular zone (SVZ) of the lateral ventricles, the dentate gyrus and the olfactory bulb. Following CNS insult, NPCs from the SVZ can migrate along the rostral migratory stream (RMS), a migration of NPCs that is directed by proinflammatory cytokines.... |
2,326,662 | Increased expression of Aquaporin 4 in the rat hippocampus and cortex during trimethyltin-induced neurodegeneration. | Trimethyltin chloride (TMT) is a neurotoxicant producing neuronal degeneration and reactive astrogliosis in the mammalian central nervous system, especially the hippocampus. A previous magnetic resonance imaging investigation in TMT-treated rats evidenced dilation of lateral ventricles, also suggesting alterations in b... |
2,326,663 | Evaluation of behavioral parameters and mortality in a model of temporal lobe epilepsy induced by intracerebroventricular pilocarpine administration.<Pagination><StartPage>875</StartPage><EndPage>879</EndPage><MedlinePgn>875-879</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/WNR.000000000000020... | The pilocarpine model of temporal lobe epilepsy (TLE) is a useful tool that is used to investigate the mechanisms underlying the generation and maintenance of seizures. Although this model has been modified significantly to reduce mortality and to promote the appearance of spontaneous recurrent seizures, to date, no de... |
2,326,664 | New Insight: Preperimetric Homonymous Hemianopia. | A 29-year-old man was referred to our institution for a visual function evaluation 14 months after a traffic accident. His best-corrected visual acuity was 1.0 in both eyes. Brain magnetic resonance imaging revealed multifocal encephalomalacic changes in the left frontal and left temporal cortical and subcortical regio... |
2,326,665 | Late gadolinium enhancement assessed by cardiac magnetic resonance imaging in heart transplant recipients with different stages of cardiac allograft vasculopathy. | Cardiac allograft vasculopathy (CAV), which limits long-term survival after heart transplantation (HTX), is usually evaluated by coronary angiography (CA). Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) is a non-invasive technique that can detect CAV-related myocardial infarctions. We aimed to investi... |
2,326,666 | [The 2013 Sixto Obrador Award. A triple-axis topographical model for surgical planning of craniopharyngiomas. Part I: historical review of the topographical diagnosis and classification schemes of craniopharyngiomas]. | This study reviews the historical evolution of pathological, neuroradiological and surgical evidence that influenced the topographical concepts and classification schemes of craniopharyngiomas.</AbstractText>An extensive, systematic analysis of the surgical series of craniopharyngiomas reported in the literature was pe... |
2,326,667 | Determination of homocysteine in cerebrospinal fluid as an indicator for surgery treatment in patients with hydrocefalus. | Increased homocysteine levels in serum are typical features of neurodegenerative brain diseases including hydrocephalus. The most frequent therapeutic approach consists of the insertion of a shunt, connecting the brain ventricles to an alternative drainage site. To decide whether the patient should undergo this, the lu... |
2,326,668 | Analytical evidence of heterogeneous lead accumulation in the hypothalamic defence area and nucleus tractus solitarius. | Lead is a potent toxicant associated with adverse cardiovascular effects and hypertension in children. Yet, few studies have determined if autonomic dysfunction associated with lead exposure involves brain regions which regulate autonomic responses. Central autonomic nuclei such as the nucleus tractus solitarius (NTS) ... |
2,326,669 | Electrical properties of kisspeptin neurons and their regulation of GnRH neurons. | Kisspeptin neurons are critical components of the neuronal network controlling the activity of the gonadotropin-releasing hormone (GnRH) neurons. A variety of genetically-manipulated mouse models have recently facilitated the study of the electrical activity of the two principal kisspeptin neuron populations located in... |
2,326,670 | MicroRNA-363 negatively regulates the left ventricular determining transcription factor HAND1 in human embryonic stem cell-derived cardiomyocytes. | Posttranscriptional control of mRNA by microRNA (miRNA) has been implicated in the regulation of diverse biologic processes from directed differentiation of stem cells through organism development. We describe a unique pathway by which miRNA regulates the specialized differentiation of cardiomyocyte (CM) subtypes.</Abs... |
2,326,671 | Acute cerebellitis with hydrocephalus. | We report a case of an 8 years old child who presented with sudden onset of headache and vomiting. He had broad-based gait and intention tremors on admission. MRI brain revealed isointense signals on T1-weighted imaging and hyperintense signals on T2-weighted imaging. Cerebellar swelling was also identified with signif... |
2,326,672 | Nesfatin-1 influences the excitability of glucosensing neurons in the dorsal vagal complex and inhibits food intake. | Nesfatin-1 is a recently discovered metabolic peptide hormone that decreases food intake after lateral, third, or fourth brain ventricle; cisterna magna; or paraventricular nucleus (PVN) injection in ad libitum fed rats. Additional micro-injection studies will improve the understanding of how nesfatin-1 acts on the bra... |
2,326,673 | Ameliorative role of gemfibrozil against partial abdominal aortic constriction-induced cardiac hypertrophy in rats.<Pagination><StartPage>725</StartPage><EndPage>730</EndPage><MedlinePgn>725-30</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1017/S104795111400081X</ELocationID><Abstract><AbstractText... | Fibrates are peroxisome proliferator-activated receptor-α agonists and are clinically used for treatment of dyslipidemia and hypertriglyceridemia. Fenofibrate is reported as a cardioprotective agent in various models of cardiac dysfunction; however, limited literature is available regarding the role of gemfibrozi... |
2,326,674 | The functional significance of newly born neurons integrated into olfactory bulb circuits. | The olfactory bulb (OB) is the first central processing center for olfactory information connecting with higher areas in the brain, and this neuronal circuitry mediates a variety of odor-evoked behavioral responses. In the adult mammalian brain, continuous neurogenesis occurs in two restricted regions, the subventricul... |
2,326,675 | A rare immature teratoma of the tela chorioidea of the third ventricle: late-onset, intrapartum ultrasound diagnosis and postnatal outcome. | We describe a previously unreported case of immature teratoma originating from the tela chorioidea of the third ventricle diagnosed during labor at term of pregnancy. Postnatal MR imaging and pediatric neurosurgery with postnatal outcome at 6 months of age are reported. |
2,326,676 | Incidental findings on preoperative computed tomography for nonsyndromic single suture craniosynostosis. | Although the diagnosis of nonsyndromic single suture craniosynostosis (NSSC) can usually be made by clinical examination, computed tomography (CT) is still commonly used in preoperative evaluation. This practice has been questioned in light of recent studies that document a small, but measurable, increased risk of mali... |
2,326,677 | Quantification of white matter fibre pathways disruption in frontal transcortical approach to the lateral ventricle or the interventricular foramen in diffusion tensor tractography. | Pathologies occupying the interventricular foramen (foramen of Monro - FM) or the anterior part of lateral ventricle (LV) are accessed by the transcortical or transcallosal route. As severing of rostral corpus callosum has been deemed inferior to cortical incision, the approaches through various points of frontal lobe ... |
2,326,678 | Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice. | Air pollution has been associated with adverse neurological and behavioral health effects in children and adults. Recent studies link air pollutant exposure to adverse neurodevelopmental outcomes, including increased risk for autism, cognitive decline, ischemic stroke, schizophrenia, and depression.</AbstractText>We so... |
2,326,679 | Acetate supplementation modulates brain adenosine metabolizing enzymes and adenosine A₂A receptor levels in rats subjected to neuroinflammation. | Acetate supplementation reduces neuroglia activation and pro-inflammatory cytokine expression in rat models of neuroinflammation and Lyme neuroborreliosis. Because single-dose glyceryl triacetate (GTA) treatment increases brain phosphocreatine and reduces brain AMP levels, we postulate that GTA modulates adenosine meta... |
2,326,680 | [A case of intraventricular dissemination arising from hepatocelullar carcinoma effectively treated with intrathecal administration of methotrexate]. | A 78-year-old man with hepatocellular carcinoma was admitted to our hospital for vertigo after transcatheter arterial chemoembolization. Contrast-enhanced magnetic resonance imaging revealed metastasis in the cerebellar vermis. Although the cerebellar metastasis decreased in size after cyberknife radiotherapy, multiple... |
2,326,681 | A fatal case of JC virus meningitis presenting with hydrocephalus in a human immunodeficiency virus-seronegative patient. | JC virus (JCV) is the etiologic agent of progressive multifocal leukoencephalopathy, JCV granule cell neuronopathy, and JCV encephalopathy. Whether JCV can also cause meningitis has not yet been demonstrated. We report a case of aseptic meningitis resulting in symptomatic hydrocephalus in a human immunodeficiency virus... |
2,326,682 | Automatic cardiac segmentation using semantic information from random forests. | We propose a fully automated method for segmenting the cardiac right ventricle (RV) from magnetic resonance (MR) images. Given a MR test image, it is first oversegmented into superpixels and each superpixel is analyzed to detect the presence of RV regions using random forest (RF) classifiers. The superpixels containing... |
2,326,683 | Clocks for all seasons: unwinding the roles and mechanisms of circadian and interval timers in the hypothalamus and pituitary. | Adaptation to the environment is essential for survival, in all wild animal species seasonal variation in temperature and food availability needs to be anticipated. This has led to the evolution of deep-rooted physiological cycles, driven by internal clocks, which can track seasonal time with remarkable precision. Evid... |
2,326,684 | Single acute stress-induced progesterone and ovariectomy alter cardiomyocyte contractile function in female rats. | To assess how ovarian-derived sex hormones (in particular progesterone) modify the effects of single acute stress on the mechanical and biochemical properties of left ventricular cardiomyocytes in the rat.</AbstractText>Non-ovariectomized (control, n=8) and ovariectomized (OVX, n=8) female rats were kept under normal c... |
2,326,685 | Imaging genomic mapping of an invasive MRI phenotype predicts patient outcome and metabolic dysfunction: a TCGA glioma phenotype research group project. | Invasion of tumor cells into adjacent brain parenchyma is a major cause of treatment failure in glioblastoma. Furthermore, invasive tumors are shown to have a different genomic composition and metabolic abnormalities that allow for a more aggressive GBM phenotype and resistance to therapy. We thus seek to identify thos... |
2,326,686 | Polymicrogyria: a common and heterogeneous malformation of cortical development. | Polymicrogyria (PMG) is one of the most common malformations of cortical development. It is characterized by overfolding of the cerebral cortex and abnormal cortical layering. It is a highly heterogeneous malformation with variable clinical and imaging features, pathological findings, and etiologies. It may occur as an... |
2,326,687 | A computational model that predicts reverse growth in response to mechanical unloading. | Ventricular growth is widely considered to be an important feature in the adverse progression of heart diseases, whereas reverse ventricular growth (or reverse remodeling) is often considered to be a favorable response to clinical intervention. In recent years, a number of theoretical models have been proposed to model... |
2,326,688 | The microinjection of a cannabinoid agonist into the accumbens shell induces anxiogenesis in the elevated plus-maze. | This study investigated the effect of a cannabinoid agonist injected into the shell region of the nucleus accumbens (nAcb shell) on anxiety-related behaviors. The animals (male Wistar rats) were unilaterally microinjected with either ACEA (arachidonyl-2'-chloroethylamide a CB1 receptor agonist) at doses of 0.005, 0.05 ... |
2,326,689 | The Welsh study of mothers and babies: protocol for a population-based cohort study to investigate the clinical significance of defined ultrasound findings of uncertain significance. | Improvement in ultrasound imaging has led to the identification of subtle non-structural markers during the 18 - 20 week fetal anomaly scan, such as echogenic bowel, mild cerebral ventriculomegaly, renal pelvicalyceal dilatation, and nuchal thickening. These markers are estimated to occur in between 0.6% and 4.3% ... |
2,326,690 | Chronic toluene exposure induces cell proliferation in the mice SVZ but not migration through the RMS. | Abuse of toluene-containing inhalants is associated to various cognitive impairments that have been partly associated to deviation of the hippocampal neurogenesis processes during adulthood. In the present study we analyzed the effect of chronic toluene exposure (6000ppm) on cell proliferation and migration in the othe... |
2,326,691 | How do we measure pathology in PAH (lung and RV) and what does it tell us about the disease. | The current understanding of the pathology that underlies pulmonary vascular and right ventricular remodeling in pulmonary hypertension is discussed. Although recent studies underscored the importance of intima and media remodeling and, for the first time, the relevance of perivascular inflammation, much is needed to m... |
2,326,692 | Primary central nervous system cytotoxic T-cell lymphoma mimicking demyelinating disease. | A 40-year-old man visited to our hospital due to progressive right hemiparesis. Magnetic resonance imaging demonstrated a heterogeneous contrast-enhanced lesion in the left basal ganglia with compression of the ventricles. A brain biopsy did not demonstrate central nervous system (CNS) lymphoma, although acute demyelin... |
2,326,693 | [Use of intracranial translucency measurement in first trimester, beyond spina bifida]. | The intracranial translucency (IT) is described as echolucid space located in the fetal central nervous system corresponding to the fourth ventricle. Alteration in the first trimester is associated with neural tube defects (NTDs).</AbstractText>To describe as part of the ultrasonographic assessment of the first quarter... |
2,326,694 | Identification of distinct ChAT⁺ neurons and activity-dependent control of postnatal SVZ neurogenesis. | Postnatal and adult subventricular zone (SVZ) neurogenesis is believed to be primarily controlled by neural stem cell (NSC)-intrinsic mechanisms, interacting with extracellular and niche-driven cues. Although behavioral experiments and disease states have suggested possibilities for higher level inputs, it is unknown w... |
2,326,695 | Flaviviruses are neurotropic, but how do they invade the CNS? | Flaviruses (FV) are RNA viruses carried by mosquitoes. Neurological signs including acute encephalitis, meningitis and acute flaccid paralysis develop in a small percentage of infected individuals; long term sequlae are, Parkinsonism, dystonias and cognitive changes. FV neuroinfection is neurotropic involving subcortic... |
2,326,696 | Neuroradiological features of papillary glioneuronal tumor: a study of 8 cases. | The purpose of this study was to characterize the magnetic resonance imaging (MRI), and computed tomographic (CT) findings in a series of 8 patients with papillary glioneuronal tumor (PGNT).</AbstractText>The routine MRI (n = 8), DWI (n = 7), and CT (n = 4) of 8 PGNTs verified by pathologic examination were reviewed. T... |
2,326,697 | Galen and the beginnings of Western physiology. | Galen (129-c. 216 AD) was a key figure in the early development of Western physiology. His teachings incorporated much of the ancient Greek traditions including the work of Hippocrates and Aristotle. Galen himself was a well-educated Greco-Roman physician and physiologist who at one time was a physician to the gladiato... |
2,326,698 | Surgical management of meningioma of the trigone area of the lateral ventricle. | Lateral ventricular trigone meningioma is relatively rare and surgical resection is the main treatment strategy. It is a challenge to achieve total resection without any complication. We analyzed a series of cases using literature review.</AbstractText>Retrospective data was collected on patients who underwent surgical... |
2,326,699 | Endoscopic third ventriculostomy for hydrocephalus due to tectal glioma. | Tectal gliomas commonly present with hydrocephalus from obstruction of the aqueduct of Sylvius. The creation of a ventriculostomy in the floor of the third ventricle (ETV) has been previously reported to by-pass aqueduct obstruction. The goal of this study was to determine the safety and efficacy of ETV in the presence... |
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