Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
2,500 | Prolonged ventricular asystole, sinus arrest, and paroxysmal atrial flutter-fibrillation: an uncommon presentation of vasovagal syncope. | We described a 55-year-old woman with recurrent syncope, complete atrioventricular (AV) block, sparsely scattered idioventricular beats lasting for 56 seconds, and long sinus arrest recorded during the syncopal episode. Paroxysmal atrial flutter-fibrillation was also presented during Holter electrocardiograph (ECG) mon... |
2,501 | Sympathetic nerve sprouting, electrical remodeling, and increased vulnerability to ventricular fibrillation in hypercholesterolemic rabbits. | Whether hypercholesterolemia (HC) can induce proarrhythmic neural and electrophysiological remodeling is unclear. We fed rabbits with either high cholesterol (HC, n=10) or standard (S, n=10) chows for 12 weeks (protocol 1), and with HC (n=12) or S (n=10) chows for 8 weeks (protocol 2). In protocol 3, 10 rabbits were fe... |
2,502 | Serum C-reactive protein elevation in left ventricular remodeling after acute myocardial infarction--role of neurohormones and cytokines. | We previously reported that increased peak serum C-reactive protein (CRP) level after acute myocardial infarction (AMI) was a major predictor of cardiac rupture and long-term outcome. The aim of this study was to clarify the role of serum CRP elevation as a possible marker of left ventricular (LV) remodeling after AMI.... |
2,503 | Effect of diurnal variability of heart rate on development of arrhythmia in patients with chronic obstructive pulmonary disease. | We examined the possible effect of diurnal variability of heart rate on the development of arrhythmias in patients with chronic obstructive pulmonary disease (COPD). Forty-one COPD patients (M/F: 39/2, mean age: 59+/-8.5 years) and 32 (M/F: 27/5, mean age: 57+/-11 years) healthy controls were included. Twenty-four hour... |
2,504 | Cardiac arrhythmias in pregnancy: clinical and therapeutic considerations. | Pregnancy can precipitate cardiac arrhythmias not previously present in seemingly well individuals. Risk of arrhythmias is relatively higher during labor and delivery. Potential factors that can promote arrhythmias in pregnancy and during labor and delivery include the direct cardiac electrophysiological effects of hor... |
2,505 | Long-term improvements in quality of life by biventricular pacing in patients with chronic heart failure: results from the Multisite Stimulation in Cardiomyopathy study (MUSTIC). | To assess the impact of biventricular pacing on quality of life over 12 months of follow-up, 76 patients in the MUSTIC trial were evaluated by 2 instruments: The Minnesota Living with Heart Failure Questionnaire and the Karolinska Quality of Life Questionnaire. MUSTIC is a randomized, controlled study to evaluate the e... |
2,506 | Acute and long-term results of radiofrequency ablation of common atrial flutter and the influence of the right atrial isthmus ablation on the occurrence of atrial fibrillation. | The purpose of this study was to evaluate the acute success rate and long-term efficacy of radiofrequency ablation of common type atrial flutter (AFL) by using a standardised anatomical approach in a large series of patients and to assess the influence of right atrial isthmus ablation on the occurrence of atrial fibril... |
2,507 | Nicotine gum-induced atrial fibrillation. | A 39-year-old man with no prior history of atrial fibrillation was hospitalized with atrial fibrillation and a rapid ventricular rate. For the 7 months before presentation, he had been chewing nicotine polacrilex gum on his own. The week he first developed palpitations, he was chewing more than 1 piece of nicotine Pola... |
2,508 | A case of complete situs inversus. | Complete situs inversus is a rare syndrome, with overall frequency estimated at 1/10,000 births, resulting from abnormal rotation of the cardiac tube during embryogenesis, of unknown mechanism. Recent studies suggest that left-right asymmetry defects are likely to be due to genetic abnormalities in the lefty, nodal, i.... |
2,509 | [Cardioversion for atrial fibrillations: not better than ventricular rate control].<Pagination><StartPage>636</StartPage><EndPage>638</EndPage><MedlinePgn>636-8</MedlinePgn></Pagination><Abstract><AbstractText>Atrial fibrillation is a frequent cardiac arrhythmia in the elderly, which can be treated either by rate contr... | Atrial fibrillation is a frequent cardiac arrhythmia in the elderly, which can be treated either by rate control, or by rhythm control through chemical or electrical cardioversion. Rate control is easily achieved, but leaves the arrhythmia with its inherent risk of heart failure and stroke intact. Although rhythm contr... |
2,510 | Reperfusion-induced arrhythmias are suppressed by inhibition of the angiotensin II type 1 receptor. | We examined antiarrhythmic effects of drugs, including renin-angiotensin system (RAS) inhibitors, on reperfusion arrhythmias in rats in vivo. Anesthetized rats were subjected to 5 min of coronary occlusion and 30 min of reperfusion. Arrhythmia scores, calculated as the product of the type of arrhythmia (1 for ventricul... |
2,511 | Reversible myoglobinuric renal failure following rhabdomyolysis as a rare complication of cardioversion. | Reversible myoglobinuric renal failure following rhabdomyolysis that was related to repeated countershocks delivered for the treatment of refractory recurrent VT and VF attacks during acute myocardial infarction is presented in this case report, in which scan with technetium-99m pyrophosphate has been used for in the d... |
2,512 | Biventricular pacing for severe mitral regurgitation following atrioventricular nodal ablation. | A 69-year-old woman developed acute pulmonary edema and severe mitral regurgitation (MR) 2 days following an uncomplicated AV nodal (AVN) ablation and insertion of VVI pacemaker for chronic atrial fibrillation. There was no history of significant mitral valve disease. Left ventricular function was normal and there was ... |
2,513 | A case of a short-coupled variant of torsades de Pointes with electrical storm. | This case report describes a short-coupled variant of Torsades de Pointes with a characteristic ECG pattern consisting of a prominent J wave in leads V3-V6, in which an electrical storm was evoked with autonomic receptor stimulation and a blockade test. The patient's frequent VF attacks were triggered by short-coupled ... |
2,514 | Postoperative ventricular arrhythmias after cardiac surgery: immediate- and long-term significance. | AF is frequent after cardiac surgery. However, ventricular arrhythmias are less known. The purpose of the study was to evaluate the causes and the prognostic significance of severe ventricular arrhythmias occurring after cardiac surgery. For 10 years, among 2,100 cardiac surgeries, 16 (0.8%) patients (13 men, 3 women; ... |
2,515 | Prospective randomized comparison of two defibrillation safety margins in unipolar, active pectoral defibrillator therapy. | Various techniques are used to establish defibrillation efficacy and to evaluate defibrillation safety margins in patients with an ICD. In daily practice a safety margin of 10 J is generally accepted. However, this is based on old clinical data and there are no data on safety margins using current ICD technology with u... |
2,516 | Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients. | The cardiac safety of a once-a-day 200 mg controlled-release formulation of flecainide acetate in the prevention of paroxysmal atrial fibrillation (PAF) was assessed in outpatients.</AbstractText>The drug was administered for 24 weeks to 227 patients diagnosed with recurrent Paf episodes. Cardiac safety was assessed pr... |
2,517 | Blunt chest trauma: an experimental model for heart and lung contusion. | Blunt chest trauma is an important clinical problem leading to injury of the heart and lungs that may be fatal. Experimental models in large animals have been developed previously. This study was aimed at developing a small-animal (rat) model for the purpose of evaluating blunt chest trauma.</AbstractText>Blunt trauma ... |
2,518 | Pulmonary venous flow by doppler echocardiography: revisited 12 years later. | In 2003, pulmonary venous flow (PVF) evaluation by Doppler echocardiography is being used daily in clinical practice. Twelve years ago, we reviewed the potential uses of PVF in various conditions. Some of its important uses in cardiology have materialized, while others have not and have been supplanted by newer approac... |
2,519 | Cardiopulmonary bypass strategy during concomitant surgical treatment of mitral valve disease and atrial fibrillation. | In recent years, the popularity of simplified intraoperative ablation approaches to treat atrial fibrillation (AF) has been progressively increasing. Our group has described a left atrial procedure based on epicardial radio frequency ablation on cardiopulmonary bypass (CPB). We report our CPB and myocardial protection ... |
2,520 | A new tool for estimating left ventricular ejection fraction derived from wall motion score index. | Radionuclide angiography (RNA) and echocardiography (biplane Simpson method) are the most accepted techniques for left ventricular ejection fraction (LVEF) assessment. A new method to evaluate LVEF based on the regional wall motion assessment of the LV was attempted.</AbstractText>To develop a simple method for LVEF es... |
2,521 | Physician specialty and quality of care for CHF: different patients or different patterns of practice? | Previous reports have suggested that internists employ evidence-based care for congestive heart failure (CHF) less frequently than cardiologists. Reasons for this possible difference are unclear.</AbstractText>A retrospective review of 185 consecutive patients admitted to a Canadian tertiary care facility between April... |
2,522 | CCORT/CCS quality indicators for congestive heart failure care. | Quality indicators are measurement tools for assessing the structure, processes and outcomes of care. Although quality indicators have been developed in other countries, Canadian cardiovascular disease indicators do not exist.</AbstractText>To develop quality indicators for measuring and improving congestive heart fail... |
2,523 | Effects of burst stimulation during ventricular fibrillation on cardiac function after defibrillation. | The purpose of defibrillation is to rapidly restore blood flow and tissue perfusion following ventricular fibrillation (VF) and shock delivery. We tested the hypotheses that 1) a series of 1-ms pulses of various amplitudes delivered before the defibrillation shock can improve hemodynamics following the shock, and 2) th... |
2,524 | KCNQ1 mutations in patients with a family history of lethal cardiac arrhythmias and sudden death. | Long QT syndrome (LQTS) is the prototype of the cardiac ion channelopathies which cause syncope and sudden death. LQT1, due to mutations of KCNQ1 (KVLQT1), is the most common form. This study describes the genotype-phenotype characteristics in 10 families with mutations of KCNQ1, including 5 novel mutations. One hundre... |
2,525 | Echocardiographic markers of severe tricuspid regurgitation associated with right-sided congestive heart failure. | Severe tricuspid regurgitation (TR), diagnosed with echocardiography, is not necessarily symptomatic. The study aim was to identify echocardiographic markers associated with right-sided congestive heart failure (RCHF) in patients with severe TR.</AbstractText>Ninety-six patients (30 males, 66 females; mean age 67 +/- 1... |
2,526 | Quality of life after mitral valve surgery: differences between reconstruction and replacement. | Quality of life (QoL) is of increasing interest in major surgical procedures. Mitral valve reconstruction (MRr) is assumed to be better tolerated than mitral valve replacement (MVR). The study aim was to assess mid-term QoL in patients undergoing isolated mitral valve surgery.</AbstractText>QoL was monitored in 115 con... |
2,527 | Prediction of paroxysmal atrial fibrillation after aortic valve replacement in patients with aortic stenosis: identification of potential risk factors. | Paroxysmal atrial fibrillation (AF) is a frequent complication after cardiac surgery. The study aim was to identify preoperative predictors of risk for this condition in patients with aortic stenosis after aortic valve replacement.</AbstractText>The influence of clinical, echocardiographic and 24 h electrocardiogram (E... |
2,528 | Effect of atrial fibrillation and an irregular ventricular response on sympathetic nerve activity in human subjects. | Although the hemodynamic changes associated with atrial fibrillation (AF) have been extensively studied, the neural changes remain unclear. We hypothesized that AF is associated with an increase in sympathetic nerve activity (SNA) and that the irregular ventricular response contributes to this state of sympathoexcitati... |
2,529 | Arterial hypertension, left ventricular geometry and QT dispersion in a middle-aged Estonian female population. | The aim of the present study was to determine the prevalence of Left ventricular hypertrophy (LVH) and different left ventricular (LV) geometric patterns in the middle-aged women population of Tallinn, to assess the relationship between LV geometry, age, blood pressure and LV repolarization duration and inhomogeneity. ... |
2,530 | Microdislodgment of ventricular pacing lead undetectable during rapid pacing one year after implantation. | A 71-year-old woman had undergone valvular heart surgery in 1981, and implantation of a permanent ventricular pacemaker for ventricular pauses during atrial fibrillation in 2001. One year after pacemaker implantation, she complained of faintness. When pacing at 100 beats/min the pacemaker functioned properly. However, ... |
2,531 | Open-chest epicardial "surgical" defibrillation: biphasic versus monophasic waveform shocks. | The aim of the study was to compare biphasic versus monophasic shocks for open-chest epicardial defibrillation. Transthoracic biphasic waveform shocks require less energy to terminate ventricular fibrillation compared to monophasic waveform shocks. However, if biphasic shocks are effective for open-chest epicardial ("s... |
2,532 | Paced QT dispersion and QT morphology after radiofrequency atrioventricular junction ablation: impact of left ventricular function. | Catheter ablation of the atrioventricular junction (AVJ) is a widely accepted treatment for drug refractory atrial fibrillation. Unfortunately, there have been some reports of pause dependent ventricular arrhythmias associated with QT interval prolongation, mainly in patients with reduced LV function. The present inves... |
2,533 | Circadian variation in ventricular tachycardia and atrial fibrillation in a medical-cardiological ICU. | To assess the diurnal distribution of ventricular tachycardia (VT) and atrial fibrillation (AF) in critically ill patients.</AbstractText>Prospective observational study (episode-based design) in an eight-bed medical/cardiological ICU at a university hospital that also admits postoperative patients.</AbstractText>98 co... |
2,534 | Prospective study of sudden cardiac death among women in the United States. | There are few data regarding the determinants of sudden cardiac death (SCD) in women, primarily because of their markedly lower rate of SCD compared with men. Nonetheless, existing data, although sparse, suggest possible gender differences in risk factors for SCD.</AbstractText>In this prospective cohort of 121 701 wom... |
2,535 | Defibrillator Versus beta-Blockers for Unexplained Death in Thailand (DEBUT): a randomized clinical trial. | Sudden Unexplained Death Syndrome (SUDS) is the leading cause of death in young, healthy, Southeast Asian men. The role of an implantable cardioverter defibrillator (ICD) for mortality reduction in these patients remains unclear.</AbstractText>The Defibrillator Versus beta-Blockers for Unexplained Death in Thailand (DE... |
2,536 | Digoxin remains useful in the management of chronic heart failure. | Despite the introduction of a variety of new classes of drugs for the management of heart failure, digoxin continues to have an important role in long-term outpatient management. A wide variety of placebo-controlled clinical trials have unequivocally shown that treatment with digoxin can improve symptoms, quality of li... |
2,537 | Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads. | Mutations in the SCN5A gene can lead to the Brugada syndrome, a genetically inherited form of idiopathic ventricular fibrillation that has a characteristic ECG phenotype usually restricted to precordial leads V1-V3. We identified a novel G752R SCN5A missense mutation leading to various degrees of the Brugada ECG phenot... |
2,538 | Clinical investigation of a new dual-chamber implantable cardioverter defibrillator with improved rhythm discrimination capabilities. | Despite continuing advances, inappropriate implantable cardioverter defibrillator (ICD) therapies in response to nonventricular tachyarrhythmias continue to cause patient discomfort and increased follow-up demands.</AbstractText>We investigated the performance of a new dual-chamber ICD (Photon DR, St. Jude Medical), wi... |
2,539 | Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function. | We previously showed that an angiotensin-converting enzyme inhibitor (captopril) or an angiotensin receptor blocker (losartan) reduced infarct size and improved endothelial function in a rat model of ischaemia-reperfusion. The present study was undertaken to see if aspirin (ASA) antagonised the beneficial effects of ca... |
2,540 | Linguistic analysis of the human heartbeat using frequency and rank order statistics. | Complex physiologic signals may carry unique dynamical signatures that are related to their underlying mechanisms. We present a method based on rank order statistics of symbolic sequences to investigate the profile of different types of physiologic dynamics. We apply this method to heart rate fluctuations, the output o... |
2,541 | Evidence for time-dependent maximum increase of free radical damage and eicosanoid formation in the brain as related to duration of cardiac arrest and cardio-pulmonary resuscitation. | Recovery of neurological function in patients following cardiac arrest and cardiopulmonary resuscitation (CPR) is a complex event. Free radical induced oxidative stress is supposed to be involved in this process. We studied levels of 8-iso-PGF2alpha (indicating oxidative injury) and 15-keto-dihydro-PGF2alpha (indicatin... |
2,542 | Broad applicability of ultrarapid train stimulation as an efficient alternative to conventional programmed electrical stimulation. | Conventional programmed electrical stimulation (PES) is useful for establishing inducibility or noninducibility of clinical ventricular arrhythmias (VA), but is complex and time-consuming. This study compared a standard PES protocol with ultrarapid train stimulation (UTS) in a broad range of patients with and without a... |
2,543 | End tidal CO2 is a quantitative measure of cardiac arrest. | Predictors of severity of cardiac arrest or efficacy of cardiopulmonary resuscitation are few. Respiratory end tidal CO2 (ETCO) is a marker of pulmonary blood flow and, possibly, cardiac arrest. The purpose of this study was to evaluate ETCO as a quantitative marker of cardiac arrest in a human model of ventricular fib... |
2,544 | Safety of a single successful conversion of ventricular fibrillation before the implantation of cardioverter defibrillators. | Multiple successful conversions of ventricular fibrillation (VF) at 10 J below the maximum output of implantable cardioverter defibrillator (ICD) have been recommended as a minimum device implantation criterion. This recommendation is based on the probabilistic properties of defibrillation that necessitates multiple sh... |
2,545 | Rhythm discrimination by rate branch and QRS morphology in dual chamber implantable cardioverter defibrillators. | Morphology Discrimination is a discriminator based on QRS morphology analysis that has been recently implemented in dual chamber implantable cardioverter defibrillators (ICDs). Detected events are initially classified according to median atrial and ventricular rates (Rate Branch). Then, a series of discriminators (Morp... |
2,546 | Evaluation of a dual chamber implantable cardioverter defibrillator for the treatment of atrial and ventricular arrhythmias. | Eighty-nine patients with a documented history of atrial tachyarrhythmias or fibrillation (AF) received a cardioverter defibrillator designed to selectively differentiate and treat atrial and ventricular arrhythmias. Twenty-two patients received a coronary sinus lead and, therefore, could use a separate shock vector fo... |
2,547 | Value of heart rate variability to predict ventricular arrhythmias in recipients of prophylactic defibrillators with idiopathic dilated cardiomyopathy. | This study investigated the relation between heart rate variability (HRV) measured as standard deviation of normal to normal RR intervals (SDNN) on baseline 24-hour ambulatory electrocardiogram (ECG) and subsequent appropriate implantable cardioverter defibrillator (ICD) interventions in 70 patients with idiopathic dil... |
2,548 | Abnormal cardiac innervation in patients with idiopathic ventricular fibrillation. | Idiopathic ventricular fibrillation (VF) is diagnosed in up to nearly 10% of survivors of out-of-hospital cardiac arrest. The arrhythmogenic substrate is unknown. This study examined the role of cardiac innervation as a possible contributor to this arrhythmia. Eight patients with idiopathic VF were compared with eight ... |
2,549 | Ventricular dyssynchrony and risk markers of ventricular arrhythmias in nonischemic dilated cardiomyopathy: a study with phase analysis of angioscintigraphy. | Biventricular pacing is a new form of treatment for patients with dilated cardiomyopathy and ventricular dyssynchrony. Limited information is available regarding the relationship between ventricular dyssynchrony and risk markers of ventricular arrhythmias in idiopathic dilated cardiomyopathy (IDC). In 103 patients with... |
2,550 | Flecainide test in Brugada syndrome: a reproducible but risky tool. | The flecainide test is widely used in Brugada syndrome. However, its reproducibility and safety remain ill-defined. This study included 22 patients (18 men, mean age 34 years). Mutations in the SCN5A gene were found in eight patients. Two patients had aborted sudden cardiac death, 8 had syncope/presyncope, and 12 were ... |
2,551 | Enhancement of J-ST-segment elevation by the glucose and insulin test in Brugada syndrome. | The effects of glucose and insulin on J-ST-segment elevation were evaluated in seven men (mean age 45 +/- 10 years) with Brugada syndrome. Six patients had been reanimated from VF and one patient had experienced syncope. The effects of intavenous (1) pilsicainide 50 mg, (2) glucose 50 g, and (3) glucose 50 g plus regul... |
2,552 | Thromboembolic risk of patients referred for radiofrequency catheter ablation of typical atrial flutter without prior appropriate anticoagulation therapy. | Radiofrequency catheter ablation of isthmus dependent atrial flutter is considered the therapy of choice. There is, however, controversy with regard to the thrombogenicity of atrial flutter in comparison with atrial fibrillation.</AbstractText>Consecutive patients scheduled for catheter ablation of documented typical a... |
2,553 | Angiotensin-converting enzyme and endothelial nitric oxide synthase polymorphisms in patients with atrial fibrillation. | Experimental studies have shown a significant increase in angiotensin-converting enzyme (ACE) expression in atrial tissue of AF patients. ACE regulates the synthesis of endothelial nitric oxide (NO), which modulates autonomic nervous activity involved in the development of AF. The aim of the study was to evaluate the p... |
2,554 | Hemodynamic effects of alternative atrial pacing sites in patients with paroxysmal atrial fibrillation. | Recently, multisite atrial pacing has been suggested as an alternative therapy to prevent recurrences of paroxysmal atrial fibrillation (PAF). A study was conducted to compare the acute effects of biatrial (BiA), left atrial (LA), and right atrial appendage (RAA) pacing on cardiac hemodynamics. In 14 patients with PAF ... |
2,555 | Contributions of high resolution electrograms memorized by DDDR pacemakers in the interpretation of arrhythmic events. | The accuracy of information retrievable from the memories of DDDR pacing systems has been limited by the absence of actual electrograms confirming the proper sensing of spontaneous cardiac activity versus that of extraneous signals. This study examined the diagnostic power of a new arrhythmia interpretation scheme, whi... |
2,556 | Optical mapping technique applied to biventricular pacing: potential mechanisms of ventricular arrhythmias occurrence. | Although it has been suggested that multisite ventricular pacing alleviates heart failure by restoring ventricular electrical synchronization, the respective roles of voltage output, interventricular delay, and pacing sites in the development of ventricular arrhythmias occurrence have not been studied during biventricu... |
2,557 | Long-term experience with a preshaped left ventricular pacing lead. | This study describes a long-term experience with a new LV pacing lead. The study population consisted of 62 patients (85% men, 71 +/- 10 years old) with advanced dilated cardiomyopathy, in NYHA Class III or IV despite optimal drug therapy, and a QRS duration > 150 ms. Patients in sinus rhythm were implanted with a t... |
2,558 | Ibutilide versus amiodarone in atrial fibrillation: a double-blinded, randomized study. | Ibutilide, a class III antiarrhythmic drug, has been shown to convert atrial fibrillation to sinus rhythm more rapidly than procainamide or sotalol. Our objective was to compare the efficacy and safety of ibutilide and amiodarone in patients after cardiac surgery.</AbstractText>Prospective, randomized, double-blinded s... |
2,559 | [Training in cardiopulmonary reanimation with early defibrillation to nurses from the 7th area of Madrid]. | Ventricular fibrillation and ventricular tachicardia without pulse are the most frequent causes of suddenly death, therefore, it was considered that training hospitals and healthcentre nurses in identifying arritms and using properly the defibrilators was necessary. It was made by practical-theoric courses. The main ai... |
2,560 | Understanding implantable cardioverter defibrillator shocks and storms: medical and psychosocial considerations for research and clinical care. | The experience of shock is the distinguishing feature for patients with implantable cardioverter defibrillators (ICDs) and is associated with diminished psychological functioning and quality of life. Multiple shocks and ICD storm are a relatively common event among patients with ICDs (10-20%) and may present specific c... |
2,561 | High defibrillation thresholds in transvenous biphasic implantable defibrillators: clinical predictors and prognostic implications. | The aim of this study was to identify clinical characteristics that distinguish patients with high DFTs and assess the prognostic implication. DFTs testing is a lengthy, potentially painful, and a hazardous process. Little information is available concerning the identification of patients with high DFT who undergo ICD ... |
2,562 | Atrial septal versus atrial appendage pacing: feasibility and effects on atrial conduction, interatrial synchronization, and atrioventricular sequence. | Atrial septal (Se-P) and atrial appendage pacing (Ap-P) were compared in a randomized, controlled study to assess the feasibility, the reliability, and the effects of Se-P on atrial conduction, interatrial synchronization, and the AV sequence. The main baseline characteristics of the patients were comparable in both gr... |
2,563 | Oral nicorandil recaptures the waned protection from preconditioning in vivo. | 1. Protection from preconditioning (PC) wanes and is eventually lost when multiple bouts of short ischemia or a prolonged reperfusion interval precedes the following sustained ischemia. The activation of mitochondrial K(ATP) channels plays a pivotal role in the intracellular signaling of PC. We tested whether the K(ATP... |
2,564 | Outcomes of cardiac surgery in nonagenarians: a 10-year experience. | With an increasing awareness of health issues and greater emphasis on preventive medicine, the general population is living longer and healthier lives than ever before. Physicians are taking care of older patients, many of whom may require cardiac surgical procedures. Improving cardiopulmonary bypass technology allows ... |
2,565 | Early and late arrhythmias in patients in preoperative sinus rhythm submitted to mitral valve surgery through the superior septal approach. | It has been hypothesized that the use of the superior septal approach to the mitral valve can lead to postoperative loss of sinus rhythm. This study was undertaken to evaluate the early and mid-term alterations of the cardiac rhythm in patients with preoperative sinus rhythm (SR) submitted to mitral valve surgery throu... |
2,566 | What characterizes episodes of atrial fibrillation requiring cardioversion? Experience from patients with an implantable atrial cardioverter. | Episodes of paroxysmal atrial fibrillation may cause disabling symptoms. Asymptomatic episodes of paroxysmal atrial fibrillation are, however, more common than symptomatic episodes. The aim of the study was to investigate whether episodes of atrial fibrillation for which the patient requires cardioversion differ from t... |
2,567 | Effects of heart isolation, voltage-sensitive dye, and electromechanical uncoupling agents on ventricular fibrillation. | We tested whether the interventions typically required for optical mapping affect activation patterns during ventricular fibrillation (VF). A 21 x 24 unipolar electrode array (1.5 mm spacing) was sutured to the left ventricular epicardium of 16 anesthetized pigs, and four episodes of electrically induced VF (30-s durat... |
2,568 | [Guideline 'Resuscitation', revision 2002]. | In 2002, the Netherlands Resuscitation Council published a translation of guidelines on Basic Life Support, use of the Automated External Defibrillator, and Advanced Life Support for adults and children, as laid down in 2000 by the International Liaison Committee on Resuscitation. The Dutch situation has altered in tha... |
2,569 | [Efficacy of Nifekalant hydrochloride for life-threatening ventricular tachyarrhythmias in patients with resistance to lidocaine: a study of patients with out-of-hospital cardiac arrest]. | Class I antiarrhythmic agents are not always effective in the treatment of life-threatening ventricular tachycardia/ventricular fibrillation (VT/VF) especially in patients with cardiopulmonary arrest. Nifekalant hydrochloride(NIF) is a novel class III antiarrhythmic agent for malignant VT/VF. This study prospectively e... |
2,570 | I-123 MIBG imaging and heart rate variability analysis to predict the need for an implantable cardioverter defibrillator. | Iodine 123 metaiodobenzylguanidine (MIBG) imaging and heart rate variability (HRV) analysis were compared in patients with an implantable cardioverter defibrillator (ICD) who did and did not receive defibrillator discharges. Although the ICD has been shown to abort potentially fatal ventricular arrhythmias, identificat... |
2,571 | Management of arrhythmias in heart failure. | Arrhythmias continue to contribute significantly to morbidity and mortality in heart failure. Implantable defibrillators have assumed an increasingly important role in preventing sudden death and are recommended for patients who have been resuscitated from cardiac arrest, have unexplained syncope, or exhibit inducible ... |
2,572 | Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches. | Atrial fibrillation is a common arrhythmia in patients with heart failure and is responsible for substantial morbidity and mortality. Restoration and preservation of sinus rhythm, therefore, has a premium. Of the numerous treatment options available, many must be avoided because of their potential for adverse effects o... |
2,573 | Risks and benefits of rate control versus maintenance of sinus rhythm. | There are 2 fundamental approaches to managing patients with recurrent atrial fibrillation (AF): to restore and maintain sinus rhythm with cardioversion and/or antiarrhythmic drugs, or to control the ventricular rate only. Over the past few years, there have been several important prospective clinical trials comparing ... |
2,574 | Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials. | In managing atrial fibrillation (AF), the main therapeutic strategies include rate control, termination of the arrhythmia, and the prevention of recurrences and thromboembolic events. Safety and efficacy considerations are important in optimizing the choice of an antiarrhythmic drug for the treatment of AF. Recently ap... |
2,575 | Sudden cardiac death: implantable cardioverter defibrillators and pharmacological treatments. | Sudden cardiac death (SCD) is the leading cause of death in advanced heart failure and cardiomyopathy patients, regardless of the underlying causes of cardiomyopathy. Ventricular tachycardia and ventricular fibrillation are the causes of SCD. This article examines pharmacological interventions and mostly, the role of i... |
2,576 | Therapeutic hypothermia after prolonged cardiac arrest due to non-coronary causes. | Mild resuscitative hypothermia has been shown to improve neurological outcome after cardiac arrest presenting with ventricular fibrillation (VF) due to cardiac causes. We describe the experience of inducing mild hypothermia in three patients with non-cardiac causes of arrest and long delays before a return of spontaneo... |
2,577 | A comparison of alpha-methylnorepinephrine, vasopressin and epinephrine for cardiac resuscitation. | The objective of this research was to compare the effects of an alpha- and beta-adrenergic agonist, epinephrine, a selective alpha(2)-adrenergic agonist, alpha-methylnorepinephrine (alpha-MNE), and a non-adrenergic vasopressin on post-resuscitation myocardial function and duration of survival. Epinephrine continues to ... |
2,578 | Comparison of six clinically used external defibrillators in swine. | External defibrillation has long been practiced with two types of monophasic waveforms, and now four biphasic waveforms are also widely available. Although waveforms and clinical dosing protocols differ among defibrillators, no studies have adequately compared performance of the monophasic or the biphasic waveforms. Th... |
2,579 | Efficacy of CPR in a general, adult ICU. | To investigate the initial cardiopulmonary resuscitation (CPR) success rate and long term survival in an Intensive care unit (ICU) population.</AbstractText>All patients with cardiac arrest over a 2-year-period (1999-2000) in a general, adult ICU of a general hospital of Athens.</AbstractText>Retrospective collection o... |
2,580 | Characteristics and outcome among patients suffering from out of hospital cardiac arrest of non-cardiac aetiology. | To describe the epidemiology for out of hospital cardiac arrest of a non-cardiac aetiology.</AbstractText>All patients suffering from out of hospital cardiac arrest in whom resuscitation efforts were attempted in the community of Göteborg between 1981 and 2000.</AbstractText>Between October 1, 1980 and October 1, ... |
2,581 | Analysing the ventricular fibrillation waveform. | The surface electrocardiogram associated with ventricular fibrillation has been of interest to researchers for some time. Over the last few decades, techniques have been developed to analyse this signal in an attempt to obtain more information about the state of the myocardium and the chances of successful defibrillati... |
2,582 | Comparison of arrhythmia recurrence in patients presenting with ventricular fibrillation versus ventricular tachycardia in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. | Because many episodes of ventricular fibrillation (VF) are believed to be triggered by ventricular tachycardia (VT), patients who present with VT or VF are usually grouped together in discussions of natural history and treatment. However, there are significant differences in the clinical profiles of these 2 patient gro... |
2,583 | Effects of long-term exercise training on cardiac autonomic nervous activities and baroreflex sensitivity. | Reductions in tonic vagal controls of the heart and depressed baroreflex sensitivity (BRS) have been associated with a postural fall in blood pressure (BP) and the incidence of cardiac events among older people. We examined the hypothesis that BP regulation during orthostatic challenge as well as heart rate variability... |
2,584 | Sodium-hydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability. | Inhibition of the sarcolemmal sodium-hydrogen exchanger isoform-1 (NHE-1) is emerging as a promising novel strategy for ameliorating myocardial injury associated with ischemia and reperfusion. We investigated whether NHE-1 inhibition (with cariporide) could minimize mechanical and electrical myocardial abnormalities th... |
2,585 | Pre-operative balloon counterpulsation and off-pump coronary surgery for high-risk patients. | Coronary artery bypass surgery (CABG) can be performed less invasively without cardiopulmonary bypass (CPB). Multivessel off-pump CABG (OPCAB) is challenging in patients with critical left main stenosis (> 70%) and/or severe ventricular dysfunction (ejection fraction < 0.35) Our objective was the evaluation of ef... |
2,586 | Open access echocardiography: a prospective audit of referral patterns from primary care. | Following recently published recommendations and guidelines, a prospective audit of 222 consecutive patients referred for open access echocardiography was conducted over a period of three months in a large district general hospital in the UK. Our study demonstrated the waiting time for an open access echocardiogram to ... |
2,587 | Sustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: results from the GUSTO-III trial. | In many patients, ventricular arrhythmias will develop early after acute myocardial infarction. We studied the incidence, timing, and outcomes of such arrhythmias in the international Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries (GUSTO)-III trial.</AbstractText>We identified in... |
2,588 | Long-term amiodarone therapy and the risk of complications after cardiac surgery: results from the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial (CAMIAT). | This study was undertaken to determine the association between amiodarone therapy and risk of complications of cardiac surgery in patients in the randomized placebo-controlled, double-blind Canadian Amiodarone Myocardial Infarction Arrhythmia Trial.</AbstractText>Prospectively collected data regarding postoperative com... |
2,589 | Effect of sotalol and acute ventricular dilatation on action potential duration and dispersion of repolarization after defibrillation shocks. | Ventricular dilatation shortens action potential duration and increases the defibrillation threshold, whereas sotalol prolongs action potential duration and may decrease the defibrillation threshold. Whether these action potential changes remain after defibrillation shocks, and how they relate to defibrillation success... |
2,590 | Effect of pilsicainide on atrial electrophysiologic properties in the canine rapid atrial stimulation model. | The heterogeneous process of atrial electrical remodeling (AER) in the canine rapid atrial stimulation model has been previously reported although it has been reported that a sodium channel blocker might suppress the shortening of the atrial effective refractory period (AERP), its effect on long-term electrical remodel... |
2,591 | Protective effect of basic fibroblast growth factor against myocyte death and arrhythmias in acute myocardial infarction in rats. | The present study in rats investigated whether basic fibroblast growth factor (bFGF) plays an important role in cardioprotection against myocardial cell death and arrhythmias in acute myocardial infarction (AMI). After ligating the left coronary artery in 62 Wistar rats, 20 Eg of human recombinant bFGF was injected int... |
2,592 | Risk stratification for asymptomatic patients with Brugada syndrome. | Ventricular fibrillation (VF) is induced in some asymptomatic patients with Brugada syndrome (BS), but the prognostic value of programmed electrical stimulation (PES) in such patients is controversial. The clinical characteristics of 41 asymptomatic BS patients, divided into 2 groups according to whether VF was induced... |
2,593 | Left ventricular performance during acute rate control in atrial fibrillation: the importance of heart rate and agent used. | The relation between heart rate and left ventricular function during rate control in atrial fibrillation is incompletely understood.</AbstractText>Twenty-four patients (age 67 +/- 11 years) with symptomatic recent onset rapid atrial fibrillation and rapid ventricular rate (> 110 bpm) were randomly assigned to receiv... |
2,594 | Ventricular fibrillation resulting from acute right ventricular infarction from isolated occlusion of a right ventricular branch artery. | Malignant ventricular arrhythmias can result from isolated right ventricular infarction, and reports of this phenomenon in the literature are rare. We present a case of a 46-year-old man with acute onset of chest pain angiographically confirmed to be a result of isolated occlusion of a right ventricular branch artery. ... |
2,595 | The dual pathway electrophysiology of the atrioventricular conduction. A new look at an old phenomenon. | Although we soon will be marking the 100th anniversary of the discovery of the atrioventricular (AV) node, the mysteries of this most complex of all parts of the conduction system of the heart remain. We are still battling controversies related to the precise morphology of the AV node and its atrial approaches. We are ... |
2,596 | Successful implantation of cardiac defibrillators without induction of ventricular fibrillation using upper limit of vulnerability testing. | Conventionally, the implantable cardioverter-defibrillator (ICD) is tested at implantation by measurement of defibrillation threshold (DFT), which involves repeated induction of ventricular fibrillation (VF). We report our data on successful ICD implantation without VF induction using a modified upper limit of vulnerab... |
2,597 | Comparison of coronary venous defibrillation with conventional transvenous internal defibrillation in man. | Animal studies have shown that defibrillation in coronary veins is more effective than in the right ventricle. We aimed to assess the feasibility of placing defibrillation electrodes in the middle cardiac vein (MCV) in man and its impact on defibrillation requirements.</AbstractText>A prospective randomised study condu... |
2,598 | Atrial fibrillation ablation leads to long-term improvement of quality of life and reduced utilization of healthcare resources. | In some patients, rapid activation from one or several foci can lead to atrial fibrillation. This study evaluated long-term changes in quality of life and healthcare resource utilization in patients with atrial fibrillation treated by ablation of focal triggers. Thirty-three patients underwent ablation for paroxysmal a... |
2,599 | Selective atrionodal input ablation for induction of proximal complete heart block with stable junctional escape rhythm in patients with uncontrolled atrial fibrillation. | The study tests the hypothesis that ablating all inputs to the atrioventricular (AV) node can result in complete heart block with stable junctional escape rhythm.</AbstractText>We attempted atrionodal input ablation in 76 consecutive patients with uncontrolled atrial fibrillation. Fast and slow pathways were first abla... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.