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2,600 | Real-time cardiac catheter navigation on three-dimensional CT images. | Targets for ablation of atrial fibrillation, atrial flutter, and non-idiopathic ventricular tachycardia are increasingly being selected based on anatomic considerations. Because fluoroscopy provides only limited information about the relationship between catheter positions and cardiac structures, and is associated with... |
2,601 | Factors determining the duration of tracheal intubation in cardiac surgery: a single-centre sequential patient audit. | The study was designed to identify those factors associated with early tracheal extubation following cardiac surgery. Previous studies have tended to concentrate on surgery for coronary artery bypass or on other selected cohorts.</AbstractText>Sequential cohort analysis of 296 unselected adult cardiac surgery patients ... |
2,602 | Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat. | This study was designed to compare the haemodynamic, electrophysiological and pharmacodynamic effects of three selective inhibitors of the different isoenzyme forms of phosphodiesterase (PDE) on ischaemia-induced dysrhythmias in the anaesthetized rat. The drugs used were pimobendan, a selective PDE III inhibitor, rolip... |
2,603 | [Long-term efficacy of combination therapy using antiarrhythmic agents and angiotensin converting enzyme inhibitor in patients with paroxysmal and persistent atrial fibrillation: importance of the timing of administration]. | This study examined the long-term efficacy of combination therapy using antiarrhythmic agents and angiotensin converting enzyme inhibitor (ACE-I) to maintain sinus rhythm in patients with paroxysmal and persistent atrial fibrillation (Paf). There were 246 patients (176 men, 70 women, mean age 67.3 +/- 11.7 years, mean ... |
2,604 | Clinical relevance of atrial fibrillation/flutter, stroke, pacemaker implant, and heart failure in Emery-Dreifuss muscular dystrophy: a long-term longitudinal study. | Emery-Dreifuss muscular dystrophy (EDMD) is a rare inherited disorder associated with cardiac involvement. We investigated the spectrum and relevance of the cardiac manifestations of EDMD, focusing on bradyarrhythmias and tachyarrhythmias (including atrial fibrillation/flutter), embolic stroke, and heart failure.</Abst... |
2,605 | Amiodarone-induced postrepolarization refractoriness suppresses induction of ventricular fibrillation. | It is still incompletely understood why amiodarone is such a potent antiarrhythmic drug. We hypothesized that chronic amiodarone treatment produces postrepolarization refractoriness (PRR) without conduction slowing and that PRR modifies the induction of ventricular arrhythmias. In this study, the hearts of 15 amiodaron... |
2,606 | [Torsades de pointes ventricular tachycardia induced by intravenous amiodarone]. | The authors report on the case history of a 61 year old woman with hyperthyroidism induced atrial fibrillation, tachycardiomyopathy and congestive heart failure, in whom life threatening ventricular proarrhythmia (torsades de pointes) developed in response to intravenous amiodarone. The patient in a septic state was re... |
2,607 | Older patients fare better with the Ross operation. | The Ross operation has an established position in young patients. We address the question of whether any age group profits most from the Ross operation, and we compare the results in various ages.</AbstractText>From February 1995 to August 2001 we performed 250 Ross operations. Group 1 consisted of 46 patients, ages 2 ... |
2,608 | Improved neurohormonal markers of ventricular function after restoring sinus rhythm by the Maze procedure. | Clinical results of the Maze procedure for treatment of atrial fibrillation (AF) are excellent, suggesting improved ventricular function after restoring sinus rhythm. However, long-term corresponding effects on the release of cardiac natriuretic peptides and other vasoactive hormones are incompletely investigated after... |
2,609 | [Out-of-hospital cardiac arrest. Mechanisms and treatment with automated external defibrillator]. | In Denmark, approximately 4500 persons suffer yearly from an out-of-hospital cardiac arrest with mortality close to 100%. The principal arrhythmia is ventricular fibrillation, which can only be treated effectively with prompt external defibrillation. Automatic external defibrillators (AED) are small, portable, easily o... |
2,610 | Angiotensin II subtype AT1 receptor blockade prevents hypertension and renal insufficiency induced by chronic NO-synthase inhibition in rats. | Aim of the present study was to investigate the influence of the angiotensin II (ANG II) subtype 1 (AT(1)) receptor blockers fonsartan and losartan on blood pressure, cardiac -dynamics and -metabolism as well as functional and morphological changes in the kidney of rats after long-term inhibition of the nitric oxide (N... |
2,611 | [Reversible thyrotoxic cardiomyopathy--report of three cases]. | Three patients with thyrotoxicosis, atrial tachyarrhythmia and congestive heart failure despite successful treatment of hyperthyroidism revealed atrial fibrillation/flagellation and left ventricular systolic dysfunction. Congestive heart failure resolved and left ventricular systolic function normalized only after succ... |
2,612 | Physiologic predictors of survival in post-traumatic arrest. | Traumatic cardiac or pulmonary arrest is often associated with a dismal outcome and is considered by many to be an example of medical futility and inappropriate use of resources. This study aimed to identify the predictors of survival in patients experiencing traumatic cardiac arrest. We retrospectively reviewed all tr... |
2,613 | Coronary surgery with non-cardioplegic methods in patients with advanced left ventricular dysfunction: immediate and long term results. | To evaluate perioperative results and long term survival in patients with severe left ventricular (LV) dysfunction undergoing coronary artery bypass grafting (CABG) using non-cardioplegic methods.</AbstractText>From April 1990 through December 1999, 4100 consecutive patients underwent isolated CABG using hypothermic ve... |
2,614 | Nucleotide changes in the translated region of SCN5A from Japanese patients with Brugada syndrome and control subjects. | The mutations of the SCN5A gene have been implicated to play a pathogenetic role in Brugada syndrome, which causes ventricular fibrillation. To determine the Brugada-associated mutations in Japanese patients, facilitate pre-symptomatic diagnosis, and allow genotype-phenotype studies, we screened unrelated patients with... |
2,615 | Implantable cardioverter defibrillators in primary and secondary prevention: a systematic review of randomized, controlled trials. | Sudden cardiac death is common in persons with cardiovascular disease.</AbstractText>To assess the efficacy of implantable cardioverter defibrillators (ICDs) in persons at increased risk for sudden cardiac death.</AbstractText>MEDLINE (1980-2002), EMBASE (1980-2002), Cochrane Controlled Clinical Trial Registry (2002, V... |
2,616 | Off-pump coronary artery bypass grafting and transmyocardial laser revascularization via a left thoracotomy. | Off-pump coronary artery bypass grafting may be combined with adjunctive transmyocardial laser revascularization to optimize revascularization. This approach may be advantageous for high-risk patients, particularly those having undergone previous sternotomies. From October 2000 through May 2001, 17 patients (9 women an... |
2,617 | Delaying defibrillation to give basic cardiopulmonary resuscitation to patients with out-of-hospital ventricular fibrillation: a randomized trial. | Defibrillation as soon as possible is standard treatment for patients with ventricular fibrillation. A nonrandomized study indicates that after a few minutes of ventricular fibrillation, delaying defibrillation to give cardiopulmonary resuscitation (CPR) first might improve the outcome.</AbstractText>To determine the e... |
2,618 | Remodelling after surgical repair of atrial septal defects within the oval fossa. | In a retrospective study, we analysed the data from 101 adults with echocardiographic follow-up after surgical repair of defects within the oval fossa at a mean age of 35 +/- 17 years; 56% of the cohort being above the age of 30 years. Mean age at follow-up was 44 +/- 18 years, and length of follow-up was up to 40 year... |
2,619 | [Staging and diagnosis in accidental hypothermia]. | Core body temperature below 35 degrees C is defining arbitrarily hypothermia. There is no worldwide consensus concerning the staging and resuscitation strategies in such a vital emergency, not even in rewarming strategy. Accidental hypothermia has its own "survival chain", modifying some steps or the timing in the comm... |
2,620 | Antiarrhythmic therapy in heart failure. | Heart failure is the term used for a cardiovascular syndrome whose definition lacks uniform criteria. It is associated with a very high mortality rate. Approximately 50% of deaths in patients with heart failure are sudden, mostly due to ventricular tachycardia (VT). In severe heart failure, death may also occur due to ... |
2,621 | Short and long-term single-centre experience with an S-shaped unipolar lead for left ventricular pacing. | Left ventricular-based pacing is an established method for treatment of congestive heart failure in patients with ventricular dyssynchrony. The transvenous epicardial approach is the method of choice to pace the left ventricle.</AbstractText>To evaluate short and long-term stability and pacing and sensing performance o... |
2,622 | The DDDR closed loop stimulation for the prevention of vasovagal syncope: results from the INVASY prospective feasibility registry. | The contraction dynamics of the ventricular myocardium are affected before and during vasovagal fainting suggesting that the Closed Loop Stimulation (CLS) pacemaker could be useful for the treatment of these patients. CLS is a new concept of heart rate modulation in cardiac pacing. The pacemaker INOS(2) CLS (Biotronik,... |
2,623 | Transjugular liver biopsy in patients with hematologic malignancy and severe thrombocytopenia. | The purposes of this study are to report experience with transjugular liver biopsy (TJLB) in patients with hematologic malignancy and severe thrombocytopenia and to determine the incidence of hemorrhage-related complications in patients with prebiopsy and pretransfusion platelet counts of 30 x 10(9) /L or lower to prop... |
2,624 | Thrombolytic therapy with recombinant streptokinase for prosthetic valve thrombosis. | Thrombosis is a serious complication of prosthetic heart valves, and management is often difficult. Thrombolytic therapy is a promising alternative to valve re-operation in the prosthetic valve thrombosis.</AbstractText>Fifteen consecutive patients with prosthetic heart valve thrombosis (10 mitral, 3 aortic, 2 tricuspi... |
2,625 | Hypertonic saline improves myocardial blood flow during CPR, but is not enhanced further by the addition of hydroxy ethyl starch. | To evaluate the effects of hypertonic saline (HS) and/or hydroxy ethyl starch (HES) on myocardial perfusion pressure (MPP) and blood flow (MBF), and cardiac index (CI) during and after cardiopulmonary resuscitation (CPR).</AbstractText>In 32 domestic swine (13-23.5 kg) open chest CPR was initiated after 8 min of ventri... |
2,626 | Evaluation of the in-hospital Utstein template in cardiopulmonary resuscitation in secondary hospitals. | The in-hospital Utstein template for cardiopulmonary resuscitation (CPR) was assessed in four secondary hospitals (334-441 beds) which did not have systematic data collection.</AbstractText>The reports and outcome over a period of 12 months during the years 2000-2001 were evaluated.</AbstractText>Of a total of 1690 pat... |
2,627 | Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. | Free radicals and oxidative stress play a crucial role in the pathophysiology of a broad spectrum of cardiovascular diseases including congestive heart failure, valvular heart disease, cardiomyopathy, hypertrophy, atherosclerosis and ischemic heart disease. We have demonstrated that IH636 grape seed proanthocyanidin ex... |
2,628 | Treatment of arrhythmias during pregnancy. | During pregnancy, significant changes occur in the hormonal and hemodynamic state of women that make arrhythmias more likely to occur. Palpitations are frequently reported, but are usually found to be associated with sinus tachycardia. The incidence of paroxysmal supraventricular tachycardia is increased during pregnan... |
2,629 | [First onset of panic disorder and agoraphobia induced by a series of inappropriate shocks of an implanted cardioverter/defibrillator]. | We report on a 61-year-old patient with an implanted defibrillator due to malignant arrhythmia after myocardial infarction. After several years of appropriate function, the patient suffered a cluster of 16 shocks due to a defect in the defibrillator. Soon the patient developed a panic disorder with agoraphobia which wa... |
2,630 | Leukotriene-mediated coronary vasoconstriction and loss of myocardial contractility evoked by low doses of Escherichia coli hemolysin in perfused rat hearts. | hemolysin has been implicated as an important pathogenic factor in extraintestinal infections including sepsis. We investigated the effects of coronary administration of hemolysin on cardiac function in isolated rat hearts perfused at constant flow.</AbstractText>Prospective, experimental study.</AbstractText>Research ... |
2,631 | Failing atrial myocardium: energetic deficits accompany structural remodeling and electrical instability. | The failing ventricular myocardium is characterized by reduction of high-energy phosphates and reduced activity of the phosphotransfer enzymes creatine kinase (CK) and adenylate kinase (AK), which are responsible for transfer of high-energy phosphoryls from sites of production to sites of utilization, thereby compromis... |
2,632 | Automated external defibrillator arrhythmia detection in a model of cardiac arrest due to commotio cordis. | Cardiac arrest due to chest wall blows (commotio cordis) has been reported with increasing frequency in children, and only about 15% of victims survive. Automated external defibrillators (AEDs) have been shown to be life saving in adults with cardiac arrest, but data on their use in children are limited. In a swine mod... |
2,633 | Delayed afterdepolarization inhibitor: a potential pharmacologic intervention to improve defibrillation efficacy. | Electrical and optical mapping studies of defibrillation have demonstrated that following shocks of strength near the defibrillation threshold (DFT), the first several postshock cycles always arise focally. No immediate postshock reentry was observed. Delayed afterdepolarizations (DADs) have been suggested as a possibl... |
2,634 | Three-dimensional mapping of earliest activation after near-threshold ventricular defibrillation shocks. | Following shocks with a 50% defibrillation success (DFT50) delivered from electrodes at the right ventricular (RV) apex and superior vena cava (SVC), the earliest epicardial postshock activation always appears focally in the left ventricular (LV) apex for both successful and failed shocks. Because the heart is a three-... |
2,635 | Transvenous defibrillation leads: high incidence of failure during long-term follow-up. | Patients with implantable cardioverter defibrillators (ICD) critically depend on correct functioning of their system. The aim of this study was to determine the incidence and clinical presentation of transvenous ICD lead failures during long-term follow-up.</AbstractText>The study group consisted of 261 consecutive pat... |
2,636 | Effect of coronary sinus electrode on the optimal atrial defibrillation pathway for an atrioventricular defibrillator. | Previous studies have demonstrated significant failure in converting atrial fibrillation (AF) using a conventional ventricular pathway. The aim of this study was to assess the benefit of incorporating a coronary sinus (CS) lead into the atrial defibrillation pathway in atrial defibrillation threshold (ADFT) reduction i... |
2,637 | Regional gap junction inhibition increases defibrillation thresholds. | It is clear that ischemia inhibits successful defibrillation by altering regional electro-physiology. However, the exact mechanisms are unclear. This study investigated whether regional gap junction inhibition increases biphasic shock defibrillation thresholds (DFT). Sixteen swine were instrumented with a mid-left ante... |
2,638 | [Value of NTproBNP concentration in an out-of-hospital adult population]. | The diagnosis of chronic heart failure (CHF) is based on demonstrating the cardiac origin of clinical manifestations. Echocardiography is the method of choice for the detection of left ventricular systolic dysfunction (LVSD). Brain natriuretic peptide (BNP) rises during LVSD.</AbstractText>To analyze the plasma concent... |
2,639 | Effect of cervical vagal nerve stimulation on defibrillation energy: a possible adjunct to efficient defibrillation. | The efficacy of electrical defibrillation is considered to be related to the autonomic status. In search of a possible adjunct to enhance the therapeutic performance of an implantable cardioverter-defibrillator. we investigated whether parasympathetic manipulation by cervical vagal nerve stimulation (VNS) increases def... |
2,640 | [Pathogenesis and clinical significance of atrial fibrillation]. | The authors review the current knowledge relating to the epidemiology, classification and pathogenesis of atrial fibrillation, and then discuss those cardiac electrophysiological changes that play roles in the initiation and/or maintenance of atrial fibrillation. They draw attention to the fact that atrial fibrillation... |
2,641 | Atrial fibrillation after ondansetron for the prevention and treatment of postoperative nausea and vomiting: a case report. | Even though clinical safety has been established in large studies, ondansetron has been reported to cause adverse cardiovascular events. We present a case of atrial fibrillation in association with ondansetron in the postoperative period.</AbstractText>A 47-yr-old, 81 kg female presented with a benign lump in her left ... |
2,642 | Involvement of tyrosine kinase in peroxynitrite-induced preconditioning in rat isolated heart. | We have investigated the role of tyrosine kinase in the antiarrhythmic effects of peroxynitrite preconditioning in rat isolated heart by using a tyrosine phosphatase inhibitor, sodium orthovanadate, and tyrosine kinase inhibitors, genistein and tyrphostin. Rat hearts were preconditioned by peroxynitrite administration ... |
2,643 | Amiodarone and bretylium in the treatment of hypothermic ventricular fibrillation in a canine model. | Refractory ventricular fibrillation (VF) is a complication of severe hypothermia. Despite mixed experimental data, some authors view bretylium as the drug of choice in hypothermic VF. Bretylium was removed from Advanced Cardiac Life Support guidelines, and, to date, efficacy of amiodarone in hypothermia is unknown.</Ab... |
2,644 | Factors associated with cardiac rhythm disturbances in the early post-pneumonectomy period: a study on 259 pneumonectomies. | To identify predisposing factors associated with cardiac rhythm disturbances during the early post-pneumonectomy period (first 7 postoperative days).</AbstractText>During the study period (1995-1999), 259 pneumonectomies were performed for malignant (244 cases) or benign disease (15 cases). Postoperative monitoring of ... |
2,645 | Predictors of cerebrovascular events in patients subjected to isolated coronary surgery. The importance of aortic cross-clamping. | Stroke is a major complication after coronary surgery, occurring in 1-4% of the patients. In this study, we evaluate the incidence and pre- and intraoperative risk factors for the development of a cerebrovascular accident (CVA) and the impact of such an event on perioperative mortality and on hospital length of stay.</... |
2,646 | Postinfarction ventricular septal defect closure with Amplatzer occluders. | Postinfarction ventricular septal defect (PIVSD) is a rare and life-threatening complication with high risk of both surgical and medical treatment. Another option available now is transcatheter closure. The purpose of this paper is to report the results of such treatment with Amplatzer occluders.</AbstractText>Seven pa... |
2,647 | [The best of valvular heart disease in 2002]. | For AS, besides a very thorough update by Carabello on their management, new experimental work confirms that the pathophysiology of the condition is closer to atherosclerotic and inflammatory processes than pure degeneration. Moreover this year brings a batch of long term post-operative results, one of which is an impo... |
2,648 | [The best of arrhythmias in 2002]. | In the era of evidence based medicine the year 2002 will be remembered principally for having brought the results of two large trials in areas of daily preoccupation for rhythmologists: those of atrial fibrillation and of prevention of rhythmic sudden death. The Atrial Fibrillation Following Investigation of Rhythm Man... |
2,649 | Experimental evidence of regional myocardial ischemia during beating heart coronary bypass: prevention with temporary intraluminal shunts.<Pagination><StartPage>10</StartPage><EndPage>18</EndPage><MedlinePgn>10-8</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Our center has... | The paper discusses how to choose the optimum shape of a pulse for electric defibrillation of the heart. The authors' data are given on the values of an induced field in the contracting myocardial structure when a defibrillator evokes pulses. Mono- and bipolar pulse-induced changes of the transmembranous potential on t... |
2,650 | Mitral regurgitation of degenerative etiology: should the timing of surgery be changed in the mitral valve repair era? | The timing of surgery in patients with chronic mitral regurgitation is a controversial issue. Left ventricular dysfunction progresses silently and is partly predictable; depressed left ventricular contractility sometimes accompanies a normal ejection fraction. Severe symptoms remain a clear recommendation for surgery. ... |
2,651 | [Atrial flutter with 1/1 nodo-ventricular conduction with amiodarone. From physiopathology to diagnosis]. | Atrial flutter with 1/1 nodo-ventricular conduction is a classical complication of Vaughan-Williams's Class I antiarrhythmic drugs. The increase of the flutter cycle and weak action of the antiarrhythmic on the atrioventricular node leads to 1/1 conduction of atrial depolarisation to the ventricles. In view of their ma... |
2,652 | Behaviour of the adrenergic cardiovascular drive in atrial fibrillation and cardiac arrhythmias. | Animal studies have conclusively shown that the sympathetic nervous system plays a major role not only in regulating sinus node activity but also in promoting cardiac rhythm alterations. Less univocal and often circumstantial have been the evidences collected on this issue in humans. However, the introduction of the mi... |
2,653 | [Holter EKG for the hypertensive heart disease]. | During chronic mechanical overload induced by hypertension, left ventricular hypertrophy predisposes to atrial and ventricular arrhythmias. Atrial arrhythmias, mainly atrial fibrillation, decrease cardiac output and increase the risk of embolism whereas ventricular arrhythmias remain the major cause of sudden death. In... |
2,654 | Combination of QT variability and signal-averaged electrocardiography in association with ventricular tachycardia in postinfarction patients. | The authors investigate incidence of ventricular tachycardia/ventricular fibrillation (VT/VF) in relationship with combination of noninvasive arrhythmia risk markers as left ventricular ejection fraction (LVEF), late potentials (LP), and QT variability index (QTVI) and compare the utility of their combination in associ... |
2,655 | Frequent ventricular ectopy after exercise as a predictor of death. | Exercise-induced ventricular ectopy predicts an increased risk of death in population-based cohorts. We sought to examine in a clinical cohort the prognostic importance of ventricular ectopy immediately after exercise, when reactivation of parasympathetic activity occurs. We hypothesized that ventricular ectopy after e... |
2,656 | Comparison of cardioprotective efficacy of two thromboxane A2 receptor antagonists. | The purpose of the current study was to compare the efficacy of two structurally unrelated thromboxane A (TXA ) receptor antagonists, KT2-962 and daltroban (BM 13.505), in a dog model of myocardial ischemia/reperfusion injury. Pentobarbital-anesthetized dogs were subjected to left circumflex coronary artery occlusion f... |
2,657 | Decreased left atrial appendage flow velocity with atrial fibrillation caused by negative inotropic agents: report of two cases. | Although pharmacological agents are frequently used to control ventricular rate or restore sinus rhythm of patients with atrial fibrillation (AF), there are no reports of the relationship between those agents and left atrial appendage (LAA) function. Two cases of a decrease in LAA blood flow velocity caused by negative... |
2,658 | A giant aneurysm of the circumflex coronary artery with fistulous connection to the coronary sinus: a case report. | Non-atherosclerotic coronary artery aneurysms are rare and most of them remain asymptomatic. We report a case who has a giant circumflex coronary artery aneurysm with fistulisation into the coronary sinus. The patient presents with dyspnea and palpitation due to atrial fibrillation with rapid ventricular response. The ... |
2,659 | His electrogram alternans reveal dual atrioventricular nodal pathway conduction during atrial fibrillation: the role of slow-pathway modification. | Traditional tools to study dual-pathway atrioventricular nodal (AVN) electrophysiology are not applicable in subjects with permanent atrial fibrillation (AF). The presence of fast-pathway (FP) and slow-pathway (SP) wavefronts and their possible modification remain uncertain in this condition. We demonstrated previously... |
2,660 | Sustained reentry in the left ventricle of fibrillating pig hearts. | It has been proposed that ventricular fibrillation (VF) is driven by sustained reentry. However, mapping studies have not detected such "mother rotors" in large mammalian hearts. We mapped VF from three 21x12 unipolar electrode arrays in 6 pigs. Two of the arrays were adjacent to each other on the left-ventricular epic... |
2,661 | Wavebreak formation during ventricular fibrillation in the isolated, regionally ischemic pig heart. | Both fixed and dynamic heterogeneities were implicated in the mechanism of wavebreak (WB) generation during ventricular fibrillation (VF). However, their relative roles remain unclear. We hypothesized that during ischemic VF, the WBs are produced primarily because of a fixed heterogeneity; namely, the gradient of refra... |
2,662 | Increased vulnerability to ischemia/reperfusion-induced ventricular tachyarrhythmias by pre-ischemic inhibition of nitric oxide synthase in isolated rat hearts. | The relationship between vulnerability to reperfusion-induced ventricular tachyarrhythmias, such as ventricular tachycardia (VT) and fibrillation (VF), and the endogenous activity of nitric oxide synthase (NOS) has not been well documented. The objective of the present study was to clarify whether the vulnerability to ... |
2,663 | Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1). | The sodium-hydrogen exchanger isoform-1 (NHE-1) plays an important role in the myocardial response to ischemia-reperfusion; inhibition of this exchanger protects against ischemic injury, including reduction in infarct size. Herein we describe a novel, potent, and highly selective NHE-1 inhibitor, zoniporide (CP-597,396... |
2,664 | Relation between heart rate, heart rhythm, and reverse left ventricular remodelling in response to carvedilol in patients with chronic heart failure: a single centre, observational study. | To determine whether the process of reverse left ventricular remodelling in response to carvedilol is dependent on baseline heart rate (BHR), heart rhythm, or heart rate reduction (HRR) in response to carvedilol.</AbstractText>Retrospective analysis of serial echocardiograms in 257 patients with chronic systolic heart ... |
2,665 | Effects of vasopressin on adrenal gland regional perfusion during experimental cardiopulmonary resuscitation. | Despite the important role of the adrenal gland during cardiac arrest, little is known about changes in the adrenal medullary or cortical blood flow in this setting. This study was designed to assess regional adrenal gland perfusion in the medulla and cortex during cardiopulmonary resuscitation (CPR), and after adminis... |
2,666 | Survival and normal neurological outcome after CPR with periodic Gz acceleration and vasopressin. | We showed previously that whole body periodic acceleration along the spinal axis (pGz) is a novel method of cardiopulmonary resuscitation (CPR). The ultimate assessment of the value of any CPR technique is the neurological outcome after using such a technique. In this study, we determined the neurological outcome in pi... |
2,667 | 'Event tree' analysis of out-of-hospital cardiac arrest data: confirming the importance of bystander CPR. | The British National Service Framework (NSF) for heart disease commended the 'Utstein style' for auditing out-of-hospital cardiac arrests. The NSF also set standards for pre-hospital treatment and response times. To increase the flexibility of Utstein, an 'event tree' technique is proposed as an audit tool. Event trees... |
2,668 | Evaluation of a defibrillator-basic cardiopulmonary resuscitation programme for non medical personnel. | To improve the outcome for out-of-hospital patients with ventricular fibrillation/pulseless ventricular tachycardia (VF/VT), the use of automated external defibrillators (AEDs) by first responders including non-medical personnel with a duty to respond to an emergency is recommended. A special CPR-AED course has been de... |
2,669 | Public access defibrillation in Helsinki--costs and potential benefits from a community-based pilot study. | In cardiac arrest the interval between the collapse and defibrillation may be shortened by teaching lay people to use defibrillators. We conducted a 3-year prospective, community-based study on public access defibrillation (PAD) in an urban emergency medical services system. All public sites with a cardiac arrest incid... |
2,670 | Electrical injury as a possible cause of sick sinus syndrome. | Electrical injury is a serious public health problem. Heart is one of the most frequently affected organs. Electrical injury can cause life-threatening cardiac complications such as asystole, ventricular fibrillation, and myocardial rupture. In this case report, we present a 20-yr-old male patient with sick sinus syndr... |
2,671 | Quality of life after use of the patient activated atrial defibrillator. | The aim of the study was to evaluate the effects of long-term use of the patient-activated atrial defibrillator for recurrent persistent atrial fibrillation (AF) on quality of life (QOL). Fifteen patients were implanted with the Medtronic Jewel AF 7250 device (dual chamber atrial and ventricular defibrillator) for AF o... |
2,672 | Effectiveness of percutaneous mechanical mitral commissurotomy using the metallic commissurotome in patients with restenosis after balloon or previous surgical commissurotomy. | Balloon mitral valvuloplasty has been reported to give equal or less positive results after previous commissurotomy than after a first procedure. Percutaneous mechanical mitral commissurotomy (PMMC) is a new technique that has not yet been evaluated in this subset of patients. Of 1,175 PMMC procedures (1,175 patients),... |
2,673 | Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials. | Progressive heart failure is the most common mechanism of death among patients with advanced heart failure. Cardiac resynchronization, a pacemaker-based therapy for heart failure, enhances cardiac performance and quality of life, but its effect on mortality is uncertain.</AbstractText>To determine whether cardiac resyn... |
2,674 | [Arrhythmogenic right ventricular dysplasia as a cause of "sudden cardiac death" with survival]. | A 42 year old woman was resuscitated from ventricular fibrillation. 5 months previously she had a syncope. Her nephew had died of sudden cardiac death at the age of 25 years.</AbstractText>There was no evidence for ST segment elevation, myocardial infarction or pulmonary embolism. The ECG showed right precordial T wave... |
2,675 | Prognostic and clinical significance of newly acquired complete right bundle branch block in Japan Airline pilots. | The purpose of this study was to evaluate the prognostic and clinical significance of newly acquired complete right bundle branch block (CRBBB) in airline pilots.</AbstractText>This study included pilots with acquired CRBBB, identified from a group of over 2,700 Japan Airline pilots. When the pilots applied for employm... |
2,676 | [Analysis and detection of abnormal ECG signal: ventricular tachycardia and fibrillation]. | This paper, utilizing signal power spectrum and L-Z complexity measure, analyzes the abnormal ECG: ventricular tachycardia (VT) and ventricular fibrillation (VF). And on the base of linear and nonlinear dynamics, the paper forwards a new definition of information complexity rate, deduces some relative properties and ap... |
2,677 | [The development of a 64-channel epicardial potential mapping system]. | A 64-channel epicardial potential mapping system was developed in order to study the mechanics of arrhythmia such as atrial fibrillation and ventricular fibrillation, and instruct the procedure of detecting and eliminating abnormal rhythm in experiment or clinic. The system was consist of electrode, amplifier, A/D card... |
2,678 | A novel approach to identifying antiarrhythmic drug targets. | Sudden cardiac death, secondary to ventricular fibrillation (VF), remains the leading cause of death in the USA. Recent experimental and theoretical studies suggest that VF could be caused by spiral wave re-entry. The initiation and subsequent break-up of spiral waves has been linked to electrical alternans, a phenomen... |
2,679 | Effect of atrial fibrillation on the dynamics of mitral annular area. | The mitral annulus shows dynamic changes in shape and size during the cardiac cycle. A smaller size in end-diastole is attributed to the sphincteric action of atrial systole, and this may be important for functional integrity of the mitral valve. However, the effect of atrial fibrillation (AF) on dynamic changes in mit... |
2,680 | [Clinical and experimental study of effect of yangxin fumai oral liquid in treating patients with extrasystole]. | To evaluate the therapeutic effect of Yangxin Fumai Oral Liquid (YFOL), a Chinese herbal medicine for nourishing heart and restoring pulse, in treating patients with extrasystole.</AbstractText>The effect of YFOL was observed in treating 30 patients with different kinds of extrasystole and compared with that in 30 pati... |
2,681 | Should vasopressin replace adrenaline for endotracheal drug administration? | Arginine vasopressin was established recently as a drug of choice in the treatment of cardiac arrest and in retractable ventricular fibrillation; however, the hemodynamic effect of vasopressin following endotracheal drug administration has not been fully elucidated. We compared the effects of endotracheally administere... |
2,682 | Effectiveness of direct-current cardioversion for treatment of supraventricular tachyarrhythmias, in particular atrial fibrillation, in surgical intensive care patients. | To evaluate primary success rate and effectiveness of direct-current cardioversion in postoperative critically ill patients with new-onset supraventricular tachyarrhythmias.</AbstractText>Prospective intervention study.</AbstractText>Twelve-bed surgical intensive care unit in a university teaching hospital.</AbstractTe... |
2,683 | Sudden cardiac death in dilated cardiomyopathy -- therapeutic options. | Despite routine use of angiotensin-converting enzyme (ACE) inhibitors, beta-blockers and spironolactone in patients with heart failure due to dilated cardiomyopathy (DCM), these patients still have a considerable annual mortality rate of 5-10%. Sudden unexpected death accounts for up to 50% of all deaths and is most of... |
2,684 | Molecular mechanisms of inherited ventricular arrhythmias. | Inherited ventricular arrhythmias such as the long QT syndrome (LQTS), Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia (CPVT), idiopathic ventricular fibrillation (VF), and arrhythmogenic right ventricular cardiomyopathy (ARVC) account for a relevant proportion of sudden cardiac death cases in y... |
2,685 | Atrial fibrillation in hypertension: predictors and outcome. | Incidence, determinants, and outcome of atrial fibrillation in hypertensive subjects are incompletely known. We followed for up to 16 years 2482 initially untreated subjects with essential hypertension. At entry, all subjects were in sinus rhythm. Subjects with valvular heart disease, coronary artery disease, preexcita... |
2,686 | Upper and lower limits of vulnerability to sudden arrhythmic death with chest-wall impact (commotio cordis). | In an animal model of commotio cordis, sudden death with chest-wall impact, we sought to systematically evaluate the importance of impact velocity in the generation of ventricular fibrillation (VF) with baseball chest-wall impact.</AbstractText>Sudden cardiac death can occur with chest-wall blows in recreational and co... |
2,687 | Mechanism of syncope in patients with positive adenosine triphosphate tests. | We prospectively evaluated the mechanism of syncope in patients with positive adenosine triphosphate (ATP) tests (defined as the induction of atrioventricular [AV] block with a ventricular pause >/=6 s after an intravenous bolus of 20 mg ATP).</AbstractText>Patients with unexplained syncope tend to have more positiv... |
2,688 | Detection and management of an implantable cardioverter defibrillator lead failure: incidence and clinical implications. | This study evaluated the long-term reliability of an implantable cardioverter defibrillator (ICD) lead to determine the incidence, clinical presentation, and management of lead failure.</AbstractText>Despite recent advances in ICD technology, the long-term reliability of ICD leads remains a significant problem.</Abstra... |
2,689 | Effect of regional differences in cardiac cellular electrophysiology on the stability of ventricular arrhythmias: a computational study. | Re-entry is an important mechanism of cardiac arrhythmias. During re-entry a wave of electrical activation repeatedly propagates into recovered tissue, rotating around a rod-like filament. Breakdown of a single re-entrant wave into multiple waves is believed to underlie the transition from ventricular tachycardia to ve... |
2,690 | The influence of spontaneous termination of atrial fibrillation on P wave-triggered signal-averaged electrocardiogram. | Prolongation of total filtered P wave duration (Ad) and low root mean square voltages for the last 20 ms of the P wave (LP20) on a P wave-triggered signal-averaged electrocardiogram (PSAECG) are typically observed in paroxysmal atrial fibrillation (PAF) patients. A shortening of atrial refractoriness and intra-atrial c... |
2,691 | Effects of verapamil and metoprolol on recovery from atrial electrical remodeling after cardioversion of long-lasting atrial fibrillation. | The aim of this prospective, randomized study was to investigate the effect of pretreatment with two different intracellular calcium-lowering drugs (verapamil and metoprolol) on recovery from atrial effective refractory period (AERP) shortening after internal electrical cardioversion (EC) of persistent atrial fibrillat... |
2,692 | Oral loading single dose flecainide for pharmacological cardioversion of recent-onset atrial fibrillation. | The efficacy and safety of the single oral loading dose of flecainide for cardioversion of recent-onset atrial fibrillation was examined by reviewing the trials on the subject identified through a comprehensive literature search. Most of the trials used a single dose of 300 mg for oral loading. The success rate ranged ... |
2,693 | The frequency of systolic versus diastolic heart failure in an Egyptian cohort. | All factors predisposing for congestive heart failure (CHF), such as coronary artery disease (CAD), hypertension and diabetes are increasing in prevalence in Egypt. Despite this, no data about CHF in our country are available.</AbstractText>To study the relative contribution of systolic vs. diastolic heart failure in E... |
2,694 | Blood compatibility of a newly developed trileaflet mechanical heart valve. | An ideal heart valve prosthesis, which has both the flow dynamic properties and blood compatibility of a tissue valve prosthesis and the durability of a mechanical prosthesis, does not exist. The Triflo trileaflet mechanical heart valve (MHV; Triflo Medical Inc., Irvine, CA) is a newly developed MHV prosthesis with the... |
2,695 | Clinical characteristics of induced nonclinical ventricular tachycardia in nonischemic cardiomyopathy. | The clinical significance of induced nonclinical ventricular tachycardia (NCVT) in nonischemic dilated cardiomyopathy (DCM) remains controversial. Twenty-eight patients with sustained VT or ventricular fibrillation related to DCM underwent programmed ventricular stimulation (PVS) to induce VT. However, VT was not induc... |
2,696 | Long-term follow-up of pacemakers with an Autocapture pacing system. | The aim of this study was to evaluate the safety and performance of the Autocapture pacing system during a 5-year follow-up period. The study was conducted retrospectively between May 1996 and May 2001. Sixty consecutive patients who had undergone VVI pacemaker implantation using an Autocapture program with leads 1402T... |
2,697 | Hyperthyroidism: a "curable" cause of congestive heart failure--three case reports and a review of the literature. | With the increasing incidence of coronary artery disease and the aging population, the prevalence of congestive heart failure (CHF) is increasing. In the majority of these cases the etiology is underlying coronary artery disease. Other less common causes of CHF include valvular heart disease, hypertension, alcoholic ca... |
2,698 | Post-cardiac catheterization access site complications and low-molecular -weight heparin following cardiac catheterization. | The low molecular weight heparin enoxaparin is often administered to patients on long-term anticoagulation regimens who temporarily discontinue warfarin prior to undergoing invasive procedures. The clinical outcome of all enoxaparin-treated patients who underwent cardiac catheterization or coronary artery interventiona... |
2,699 | [Indications of automatic ventricular implantable defibrillator. Implications for daily practice]. | The authors were the redactors of the Guidelines of the French Society of Cardiology for the indications of the automatic implantable defibillator, derived from the available indication in USA, and from the ulteriorly performed controlled studies. Three Class-I indications were selected: 1) circulatory arrest due to ve... |
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