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25,500 | Long-Term Results of the Treatment of Patients With Chronic Ischemia of the
Lower Limbs in Combination With Ischemic Heart Disease. | Aim To compare long-term outcomes of x-ray endovascular (percutaneous
coronary intervention, PCI, and lower limb angioplasty with stent placement,
LLA; group 1) and combination treatments (PCI and open LLA surgery; group 2) in
patients with chronic lower limb ischemia (CLLI) associated with ischemic heart
dise... |
25,501 | Features of antiplatelet therapy with P2Y12 receptor inhibitors in patients with
myocardial infarction according to the Russian Register of Acute Myocardial
Infarction REGION-MI. | Aim To study specific features of administering platelet P2Y12 receptor
inhibitors to patients with myocardial infarction (MI) in real-life clinical
practice; to reveal a possible inconsistency of the therapy with clinical
guidelines; to evaluate the patients' compliance with the medication at the
outpatient sta... |
25,502 | APACHE II score predicts in-hospital mortality more accurately than inflammatory
indices in patients with acute coronary syndrome. | Aim This study evaluated the prognostic ability of the APACHE II score and
compared it with inflammatory indices in patients with acute coronary syndrome
(ACS).Material and Methods A total of 525 patients with ACS were
retrospectively enrolled in the study. APACHE II scores were calculated and
C-reactive prot... |
25,503 | Prognostic value of non-traditional lipid parameters: Castelli Risk Index I,
Castelli Risk Index II, and triglycerides to high-density lipoprotein
cholesterol ratio among patients with non-ST-segment elevation myocardial
infarction during 1‑year follow-up. | Aim Concentrations of classical lipoproteines have a well-established role in
non-invasive cardiology. The efficacy of the Castelli Risk Index I (CRI I),
Castelli Risk Index II (CRI II), and triglycerides to high-density lipoprotein
cholesterol (TG / HDL-C) ratio in clinical practice are currently under
evaluati... |
25,504 | The relationship between pericardial effusion and pulmonary involvement,
prognosis, mortality in COVID-19 patients. | Aim Comprehensive studies on the coexistence of COVID-19 and pericardial
effusion (PEff) are limited. In this study, we investigated the relationship
between pneumonia severity and PEff, predisposing factors, and the effect of
PEff on clinical prognosis and mortality in COVID-19 patients.Material and
methods ... |
25,505 | [A case of clinically malignant rapid-progressive cardiac myxoma after COVID-19
infection]. | This article presents a clinical case of urgent, life-saving surgical
intervention in a 69-year-old woman with left atrial myxoma with rapid
morphological and clinical progression and a history of COVID-19 and breast
cancer in remission. However, the concurrent (perhaps secondary) thrombophilic
condition facilitate... |
25,506 | Features of Parenteral Anticoagulant Therapy in Patients With Myocardial
Infarction According to the Russian Register of Acute Myocardial Infarction -
REGION-IM. | Aim To study specific features of the parenteral anticoagulant therapy for
acute myocardial infarction (MI) in the Russian Federation and to evaluate the
consistency of the prescribed parenteral anticoagulant therapy with the
effective clinical guidelines.Material and methods REGION-MI, the Russian
rEGIstry f... |
25,507 | Dynamics of Regional Mortality Rates From Cardiac Causes in Russia 2019-2020. | Aim To analyze the dynamics of standardized mortality ratios (SMR)
(2019-2020) for the cardiological causes indicated as the primary (original)
cause of death, in regions of the Russian Federation, based on the RF State
Statistics Service Brief Nomenclature of Causes of Death (RFSSS BNCD). Reports
have indicat... |
25,508 | The Burden of Residual SymptOms That Complicate the Life of Patients Who Have
Suffered a new Coronavirus Infection (THROW study). | Aim To evaluate the prevalence of residual symptoms in patients
hospitalized for novel coronavirus infection at 8 months after discharge and the
severity of such symptoms depending on demographic characteristics, concurrent
diseases, and specific features of the acute period of COVID-19.Material and
methods T... |
25,509 | Prognostic value of myocardial strain by magnetic resonance imaging in
nonischemic dilated cardiomyopathy: a systematic review and meta-analysis. | Aim This study was aimed at performing a systematic review and meta-analysis
to investigate the prognostic role of left ventricular (LV) myocardial strain
variables as determined by magnetic-resonance imaging in non-ischemic dilated
cardiomyopathy.Material and methods A search was performed in PubMed
(MEDLINE... |
25,510 | The effect of ferric carboxymaltose treatment on the Tp-e interval and the
Tp-e/QT and Tp-e/QTc ratios in heart failure patients with iron deficiency. | Aim In heart failure (HF) patients with iron deficiency, cardiac electrical
irregularity is a cause of arrhythmias. The aim of our study was to evaluate the
effect of ferric carboxymaltose (FCM) treatment on T wave peak to end (Tp-e)
interval and the Tp-e / QT and Tp-e / corrected QT (QTc) ratios that reflect the... |
25,511 | Low sCD163/TWEAK Ratio at First Day After Acute Myocardial Infarction Associated
with Adverse Cardiac Remodeling in Non-Elderly Patients. | Aim In this study, we aimed to investigate the role of sCD163 / tumor
necrosis factor-like weak apoptosis-inducing (TWEAK) ratio in cardiac remodeling
in non-elderly patients diagnosed with first acute myocardial infarction
(MI).Material and Methods Forty-four patients (age ranges: 40-64 years)
diagnosed with... |
25,512 | Effects of obesity on arrhythmic events and survival in patients with an
implantable cardioverter defibrillator. | Background Studies have shown that increased body weight and obesity may be
associated with an increased risk of arrhythmic events. The aim of this study
was to evaluate the effect of obesity on the risk of arrhythmic events,
hospitalization, and death in patients who received implantable cardioverter
defibrilla... |
25,513 | [Anatomical and Functional Approaches in the Assessment of Ischemia in Ischemic
Heart Disease: Analysis of Major World Research]. | This review provides a chronology of major international studies of the effect
of evaluating transient myocardial ischemia, including with radionuclide
methods, and coronary stenosis on the choice of therapeutic strategy and
prognosis for patients with ischemic and coronary disease. The authors discussed
the ration... |
25,514 | [Complete atrioventricular block as the first manifestation of dermatomyositis]. | Dermatomyositis is a rare systemic autoimmune disease characterized by primary
damage of the skin and striated muscles with the development of chronic muscle
weakness. Due to the polymorphic nature of the clinical picture, early diagnosis
of dermatomyositis is challenging since patients may visit different specialis... |
25,515 | Prognostic Value of Subclinical Pulmonary Congestion With Stress Ultrasound of
the Lungs in the Development of Heart Failure in Patients With Primary
Myocardial Infarction and Percutaneous Coronary Intervention. | Aim To determine the clinical and prognostic significance of subclinical
pulmonary congestion, as evaluated by stress ultrasound (stress-US) examination
of the lungs, in the development of heart failure (HF) during the postinfarction
period after acute myocardial infarction (AMI) and percutaneous coronary
inte... |
25,516 | Echocardiographic Predictors of Ventricular Tachyarrhythmias in Patients With
Cardioverter-Defibrillator Implanted for Primary Prevention of Sudden Cardiac
Death. Results From a two-Year Prospective Follow-up Study. | Aim To compare variables of transthoracic EchoCG for determining
echocardiographic predictors and their prognostic role in the development of
persistent paroxysmal ventricular tachyarrhythmias (VT) in patients with
ischemic CHF who had been implanted with a cardioverter defibrillator (CD) for
primary preventio... |
25,517 | The influence of the Ini-tial Severity of Coronary Artery Lesion (by the Syntax
Score) on the Midterm Prognosis of Patients With Acute Myocardial Infarction
Without ST Segment Elevation. | Aim To study the effect of the baseline severity of coronary artery damage
according to the SYNTAX scale (baseline score of coronary lesions, BSCL) on the
mid-term prognosis in patients with non-ST segment elevation acute myocardial
infarction (AMI) (NSTEMI), and to identify the threshold BSCL value that
deter... |
25,518 | The Role of Modi-fiable and Non-Modifiable Factors in the Development of Right
and Left Ventricular Myocardial Dysfunction in High-Risk Patients. | Aim To study early manifestations of left ventricular (LV) and right
ventricular (RV) myocardial remodeling in high-risk patients.Material and
methods Intracardiac hemodynamics was studied by equilibrium radionuclide
ventriculography (ERVG) in 83 patients (mean age, 61.1±8.9 years) with preserved
LV ejection ... |
25,519 | Analysis of Clinical and Biochemical Characteristics of Patients With
Genetically Confirmed Familial Hypercholesterolemia in Russian North Western
District Residents. | Aim To compare results of clinical, laboratory, and genetic examination of
patients with familial hypercholesterolemia (FHC).Material and methods 112
patients aged 40.2±17.9 years (49 men) were examined. The gene of low-density
lipoprotein receptor (LDLR) was analyzed and evaluated using the Dutch Lipid
Clini... |
25,520 | Comparative analysis of tryptophan and downstream metabolites of the kynurenine
and serotonin pathways in patients with arterial hypertension and coronary
artery disease. | Aim To compare serum concentrations of tryptophane (Trp) and its metabolites
in subjects with no cardiovascular disease (CVD) and patients with СVD,
including arterial hypertension (AH) and ischemic heart disease (IHD).Material
and methods This study included 131 participants; 58 participants (11 of them
with... |
25,521 | Adipokines and adipocytokines in men with coronary atherosclerosis and
overweight. | Aim To study concentrations of adipokines and their associations with
proinflammatory cytokines in overweight men with coronary
atherosclerosis. Material and methods This study included 79 men aged 45-60
years with atherosclerosis who had undergone coronary endarterectomy during a
coronary bypass surgery, and... |
25,522 | Predictors of tachycardia-induced cardiomyopathy in patients with first-time
decompensation of chro-nic heart failure with reduced left ventricular ejection
fraction of nonischemic etiology and persistent atrial tachyarrhythmia. | Aim To identify possible predictors of tachycardia-induced cardiomyopathy
(TICMP) in patients with newly developed decompensated chronic heart failure
(CHF) of nonischemic origin with reduced left ventricular ejection fraction (LV
EF) and with persistent atrial tachyarrhythmias. Material and methods This
stud... |
25,523 | Associations of adipokines and metabolic hormones with low-density lipoprotein
hypercholesterolemia in men and women under 45 years of age. | Aim To study the adipokine profile in young people with hypercholesterolemia
and low-density lipoproteins (LDL) and to evaluate the relationship between
concentrations of LDL cholesterol (LDL-C) and metabolic hormones in men and
women younger than 45 years. Material and methods This study included 304
subject... |
25,524 | [Cardiac contractility modulation in heart failure with reduced ejection
fraction treatment]. | Heart failure with reduced left ventricular ejection fraction (LV EF) (HFrEF) is
a significant issue of health care due to increasing indexes of morbidity and
mortality. The emergence of a number of drugs and implantable devices for the
treatment of HFrEF has allowed improvement of patients' well-being and
prognosi... |
25,525 | [Рossibility of using European (HFA-PEFF) and American (H2FPEF) algorithms for
diagnosing heart failure with preserved ejection fraction in Russian clinical
practice]. | This article focuses on the significance of a unified approach to diagnosing
heart failure with preserved left ventricular ejection fraction (HFpEF). The key
hemodynamic index of HFpEF is increased left ventricular filling pressure (LVFP)
and its noninvasive marker, the E / e' value obtained by tissue Doppler
echoc... |
25,526 | Proactive anti-inflammatory therapy in the advanced stages of a new coronavirus
infection. Main results of the inpatient phase of the COLORIT study (Colchicin
vs. Ruxolitinib and secukinumab in an open, prospective, randomized trial in
patients with novel coronavirus infection COVID-19). | Aim To evaluate clinical efficacy of the proactive anti-inflammatory
therapy in patients hospitalized for COVID-19 with pneumonia and a risk of
"cytokine storm".Material and methods The COLORIT study was a comparative study
with randomization into 4 groups: colchicine (n=21) 1 mg for the first 3 days
followed... |
25,527 | The Effect of COVID-19 on Long-Term Cardiac Function in Patients With Chronic
Heart Failure. | Aim To evaluate functional changes in the heart in the long-term following
COVID-19 in patients with chronic heart failure (CHF).Material and methods Case
reports of 54 patients aged 69.1±9.7 years who had COVID-19 from January 2021
through January 2022 and had been previously diagnosed with NYHA functional
c... |
25,528 | Electrocardiogram QRS Complex Duration as a Predictor of Hospital Prognosis in
Patients With COVID-19. | Aim To determine the effect of major electrocardiographic (ECG) parameters
on the prognosis of patients with COVID-19.Material and methods One of systemic
manifestations of COVID-19 is heart injury. ECG is the most simple and available
method for diagnosing the heart injury, which influences the therapeutic
a... |
25,529 | Анализ влияния коморбидной сердечно-сосудистой патологии на течение и исходы
COVID-19 у госпитализированных пациентов в первую и вторую волну пандемии в
Евразийском регионе. | Цель: Изучение особенностей клинического течения новой коронавирусной инфекции
и влияния сопутствующих заболеваний на исход заболевания у госпитализированных
больных с инфекцией SARS-CoV-2 в первую и вторую волны пандемии.Методы и
результаты. Для оценки особенностей течения COVID-19 в Евразийском регионе были
со... |
25,530 | Prevalence of Heart Failure in a Megalopolis. | Aim To assess the prevalence of heart failure (HF) in St. Petersburg from
2019 through 2021 based on medical reports.Material and methods Medical records
of 146 912 patients with HF who were managed in St. Petersburg from 2019 through
2021 were analyzed. Prevalence of HF was assessed using a standard ICD-10 I ... |
25,531 | Long-term outcomes in patients with an implanted cardioverter-defibrillator
according to the Kuzbass registry. | Aim To analyze long-term outcomes by results of the prospective part of the
Kuban registry of patients with an implantable cardioverter defibrillator
(ICD).Material and methods A prospective analysis of the incidence of hard
endpoints and changes in the condition was performed for 260 patients with ICD
succes... |
25,532 | Cardiometabolic Effects of Empagliflozin in Patients Undergoing Elective
Percu-taneous Coronary Intervention for Type 2 Diabetes Mellitus. | Aim To evaluate cardiometabolic effects of empagliflozin in patients with
ischemic heart disease and type 2 diabetes mellitus (DM) following elective
percutaneous coronary intervention (PCI).Materials and methods Patients meeting
the inclusion/non-inclusion criteria were randomized into two groups of equal
num... |
25,533 | [Case of peripartum cardiomyopathy misdiagnosed as pulmonary changes due to
COVID-19]. | A 37-year-old female patient was admitted 16 days after delivery in a hospital
for infectious diseases with cough, shortness of breath, and infiltrative
changes in the lungs that were interpreted as viral pneumonia. Considering the
failure of therapy and the history, peripartum cardiomyopathy was suspected.
Examina... |
25,534 | [Анализ влияния коморбидной сердечно-сосудистой патологии на течение и исходы
COVID-19 у госпитализированных пациентов в первую и вторую волну пандемии в
Евразийском регионе]. | Цель: Изучение особенностей клинического течения новой коронавирусной инфекции
и влияния сопутствующих заболеваний на исход заболевания у госпитализированных
больных с инфекцией SARS-CoV-2 в первую и вторую волны пандемии.Методы и
результаты. Для оценки особенностей течения COVID-19 в Евразийском регионе были
со... |
25,535 | Risk Factors and Hospital Outcomes of Acute Kidney Injury in Patients Operated
on for an acquired Valvular Heart Disease. | Aim To determine predictors of acute kidney injury (AKI) related with
surgeries for correction of acquired valvular heart disease (HD) and to evaluate
the incidence of in-hospital complications in patients with postoperative
AKI.Material and methods This study included 62 patients after surgery for
correction... |
25,536 | [Regulatory Adaptive Status in Assessment of Efficacy of Pharmacotherapy and
Prognostication of Complications in Functional Class III Chronic Heart Failure]. | OBJECTIVE: to elucidate significance of regulatory adaptive status (RAS) for
assessment of effectiveness of medical treatment and prediction of
cardiovascular complications in functional class (FC) III congestive heart
failure (CHF).
MATERIAL AND METHODS: We included into this study 100 patients with hypertensive
d... |
25,537 | [Value of Two Dimensional Echocardiography for Assessment of Disease Severity in
Patients With Pulmonary Hypertension]. | AIM: To carry out complex assessment of the right ventricular (RV) function with
two-dimensional echocardiography (2D-EchoCG) for detection of most informative
markers of the disease severity in patients with pulmonary hypertension (PH).
MATERIAL AND METHODS: We examined 63 patients with PH (38 with idiopathic PH, 7 ... |
25,538 | [Bilateral Internal Mammary Grafts With Preservation of Sternum Blood Supply]. | We have prospectively collected data from 43 patients who underwent coronary
artery bypass surgery and received bilateral internal thoracic artery (ITA)
graft. Left ITA was harvested on full length from ostium to bifurcation. Right
ITA harvesting included mobilization of only its proximal stump (5-6 cm long),
that ... |
25,539 | [Infective Endocarditis: Problems of Diagnosis and Treatment]. | Results of the clinical study involving 458 patients (from 12 to 75 years, mean
age 49 +/- 9.3 years) with various forms of infective endocarditis (IE) have
been summarized. Integrated echocardiography was the principal non-invasive
method of presurgical diagnosis of the disease. Sensitivity of transthoracic
echoca... |
25,540 | [Disorders of Vasoregulative Endothelial Function, Echocardiographic Assessment
of Myocardial Dysfunction and Hemodynamics of Pulmonary Circulation in Cirrhosis
of the Liver]. | AIM: to study relationship between parameters of intracardiac hemodynamics
assessed by Doppler echocardiography and functional activity of endothelium,
hepatic blood flow and severity of portal hypertension in patients with
cirrhosis of the liver (CL) of different etiology.
RESULTS: We found that changes of structur... |
25,541 | [Myocardial Revascularization in Patients With Chronic Ischemic Heart Disease
Combined With Chronic Obstructive Pulmonary Disease]. | Currently enough data has been accumulated to consider chronic obstructive
pulmonary disease (COPD) as one of important factors of poor prognosis in
patients with coronary artery disease, possibly producing an impact on
perioperative risk during coronary artery bypass grafting surgery and
percutaneous coronary inte... |
25,542 | [Sudden Cardiac Death in Patients With Hypertrophic Cardiomyopathy]. | This literature review is devoted to the problem of studying sudden cardiac
death (SCD) in hypertrophic cardiomyopathy (HCM). It covers prevalence of SCD
and its structure among young individuals and trained athletes, contains
discussion of relation of SCD to sex, age, and hypertrophic response of
myocardium to phy... |
25,543 | [Desaggregant Therapy of Patients With Ischemic Heart Disease: Unsolved
Problems]. | At present, choice of antiplatelet therapy in ischemic heart disease (IHD)
patients depends on the IHD form, accepted treatment guidelines,
contraindications, and cost of drugs. Usually, there is no regular control of
the action of antiplatelet drugs. However, in many patients such therapy does
not improve the long... |
25,544 | [The Problem of Adherence to Anticoagulant Therapy and Ways to Its Solution]. | Suboptimal medication adherence to anticoagulation therapy is a widespread
problem and is associated with increases in risk of thromboembolic or
haemorrhagic events. Standard therapy with warfarin is associated with
suboptimal adherence due to narrow therapeutic window, frequent side effects and
need for INR contro... |
25,545 | [Trimetazidine in the Treatment of Chronic HeartFailure]. | The review presents data on alterations of mitochondrial oxidative metabolism
occuring due to heart failure, mechanisms of cytoprotective agent trimetazidine
associated with a partial inhibition of the fatty acid oxidation and increased
metabolism of pyruvate, reduction of cardiomyocyte apoptosis and oxidative
stre... |
25,546 | [The Possibility of Using Myocardial Cytoprotector Tiotriazoline in Cardiology
Practice]. | The improvement of approaches to the treatment of cardiovascular diseases is
considered the number of primary concerns of modern cardiology. It is
undoubtable that the main achievements of the last few decades are creation and
introduction into clinical practice of metabolic drugs, which mechanism of
action is asso... |
25,547 | [Intracardiac Thrombosis in a Child With Hereditary Thrombophilia]. | A child who had undergone subclavian vein catheterization in the neonatal period
was hospitalized in a grave condition at the age of 1 year 7 months with
echocardiographic signs of right ventricular thrombus. Further examination
revealed low level of protein C and mutations in methylenetetrahydrofolate
reductase an... |
25,548 | [Optimization of Control of Blood Pressure, Metabolic Disorders and Target
Organs Protection With Fixed Perindopril and Indapamide Combination in Treated
Patients With Arterial Hypertension]. | PURPOSE: to assess the potential of fixed perindopril/indapamide combination
(FPIC) to improve angioprotection in patients with arterial hypertension (AP)
with various efficacy of preceding therapy with combination of losartan and
hydrochlorothiazide (HCTZ).
MATERIAL AND METHODS: We included in this open study 50 pa... |
25,549 | [The Familial Hypercholesterolemia Caused by a Novel Human Low Density
Lipoprotein Receptor Gene Mutation c.1327 T>C (p.W433R)]. | During investigation of molecular nature of familial hypercholesterolemia (FH)
in Petrozavodsk (Russia) cohort of patients a novel low density lipoprotein
(LDL) receptor gene mutation was found. This mutation designated c.1327 T>C
(W443R [W422R]) was predicted to cause substitution of arginine for tryptophan
residu... |
25,550 | [Genetic Risk Factors of Macrovascular Complications in Patients With Type 2
Diabetes]. | High risk of macrovascular complications in patients with type 2 diabetes
mellitus (T2DM) is caused by insulin resistance and atherogenic dyslipidemia
that may be genetically determined. The aim of this study was to assess the
association of polymorphic genetic variants APOA5 (S19W/rs3135506), CETP
(Taq1B/rs708272)... |
25,551 | [Predictors of Heart Failure With Preserved Ejection Fraction in Patients With
Metabolic Syndrome and Preclinical Diastolic Dysfunction]. | PURPOSE: to evaluate differences in echocardiographic parameters between
patients with preclinical diastolic dysfunction (PDD) and heart failure with
preserved ejection fraction (HFpEF) and to identify predictors of transition
from PDD to HFpEF.
MATERIAL AND METHODS: Echocardiographic parameters were recorded in 325... |
25,552 | [The Myocardial Sleeves of the Pulmonary Veins: Potential Implications For
Atrial Fibrillation]. | Pulmonary veins (PVs) are thought to play an important role in the initiation of
atrial fibrillation. However, systematic microelectrode studies from different
regions of the left atria and PV myocardium remain limited.
METHODS AND RESULTS: A 2-microelectrode technique was used to characterize
electrophysiological p... |
25,553 | [The Evaluation of Left Ventricular Diastolic Function by Echocardiography in
Patients With Preserved Ejection Fraction]. | OBJECTIVE: to compare non-invasive evaluation of left ventricular (LV) diastolic
function (DF) by echocardiography using algorithms of the 2009 and 2016 American
Society of Echocardiography (ASE)/European Association of Echocardiography (EAE,
now European Association of Cardiovascular Imaging [EACVI]) Recommendation... |
25,554 | [Assessment of Relationship Between Cardiovascular Risk and Risk of Development
of Diabetes Mellitus]. | AIM: to analyze interrelationship between cardiovascular risk (CVR) and risk of
development of diabetes mellitus (DM) in a cohort of working age men.
MATERIAL AND METHODS: We enrolled in this study 300 men aged 40-59 years with
more or equal 1 risk factors. Examination included questionnaire, standard
clinical, inst... |
25,555 | [Myocardial Infarction and Stroke Among Railway Employees in Azerbaijan]. | We studied the incidence of myocardial infarction (MI) and stroke in two groups
of railway employees aged over 39 years including pensioners. The first (main)
group included employees (n=15 671) responsible for movement of trains and
exposed to `action of harmful occupational factors. The second (control) group
inc... |
25,556 | [Possibilities to Control Early Stages of Inflammation in and of Thrombus
Formation in Cardiovascular Pathology]. | Circulating platelet-leukocyte aggregates (PLA) are present in patients with
various diseases of the cardiovascular system and are considered as sensitive
markers of platelet activation. At the same time characteristics of PLA in the
circulating blood continue to be discussed in the context of the search for
early ... |
25,557 | [Hemodynamic Derangements in Patients With Functional Univentricular Heart:
Mechanisms of Development, Possibilities of Treatment]. | Heart failure (HF) is a predictable outcome of nearly all cardiovascular
diseases including congenital heart diseases (CHD). A special category comprises
patients with functional single ventricle (FSV) of the heart because of extreme
diversity of anatomical changes of the heart and great vessels, complex
mechanisms... |
25,558 | [A Breakthrough in the Treatment of Patients With Heart Failure With Reduced
Ejection Fraction: the Clinical Significance of the PARADIGM HF-Trial]. | The implementation into clinical practice of new therapeutic strategies that
could improve the prognosis of patients with heart failure (HF) with reduced
ejection fraction (HFrEF) remains relevant. Innovative approach is to restore
imbalances of neurohumoral systems by inhibiting angiotensin II receptor and
neprily... |
25,559 | [Combined Effect of Genetic Factors, Age, and Smoking on the Risk of Developing
Myocardial Infarction]. | OBJECTIVE: to elaborate a complex model for myocardial infarction (MI) risk
assessment considering the combined effect of genetic predisposition, age and
smoking.
MATERIALS AND METHODS: The study included two independent samples of ethnic
Russians: 325 patients with MI and 185 individuals without history of
cardiov... |
25,560 | [Comparative Efficacy of the Influence of Fixed Combinations of Antihypertensive
Drugs That Block the Renin-Angiotensin-Aldosterone System, With Thiazide
Diuretics on the Parameters of Ambulatory Blood Pressure Monitoring]. | AIM: to compare effects of fixed-dose combinations of antihypertensive drugs
that block renin-angiotensin-aldosterone system (RAAS) with hydrochlorothiazide
(HCT) on parameters of ambulatory blood pressure monitoring (ABPM).
MATERIAL AND METHODS: Patients (n=50; 25 women, 25 men aged 40-75 years) with
stage II essen... |
25,561 | [Comparison of Verapamil and Amlodipine for Treatment of Chronic Heart Failure
With Preserved Left Ventricular Ejection Fraction in Patients With Hypertensive
Disease]. | OBJECTIVE: to compare efficacy of verapamil and amlodipine in treatment of
chronic heart failure (CHF) with preserved left ventricular (LV) ejection
fraction (EF) in patients with hypertensive disease (HD).
MATERIAL AND METHODS: Patients with stage III HD, class II-III CHF, and LVEF
more or equal 50% (n=167, age 48-... |
25,562 | [Assessment of Impact of Acute Kidney Injury on Prognosis of a Hospitalized
Patients With Acute Decompensated Heart Failure]. | OBJECTIVE: to assess prevalence of acute kidney injury (AKI) among patients with
acute decompensated heart failure (ADHF) and its impact on prognosis in a
hospitalized patient.
MATERIAL AND METHODS: a sample of patients hospitalized with signs of ADHF.
RESULTS: Prevalence of AKI in this sample was 23.1%. There was no... |
25,563 | [The Prediction Model of Cardiovascular Events Among the Russian Population:
Methodological Aspects]. | Modeling is the common approach for predicting not only the population health,
but also the social and economic burden of disease, which is an important
argument while making decisions in health care and prevention.
AIM: To develop the model for predicting cardiovascular risk, applicable for the
assessment of clinic... |
25,564 | [Cardio-hepatic Syndrome in Heart Failure: Prevalence, Pathogenesis and
Prognostic Significance]. | In a framework of the concept of organ interactions great attention has been
paid during recent years to interaction of the heart and liver. The term
cardio-hepatic syndrome (CHS) designates the combination of clinical-laboratory
signs of liver dysfunction and acute or chronic cardiac pathology. In this
article, we... |
25,565 | [Cardiooncology: Current Aspects of Prevention of Anthracycline Toxicity]. | Anthracyclines including doxorubicin, epirubicin, daunorubicin, aclarubicin are
extensively used as chemotherapeutic agents for treatment of hematological and
other malignancies. In cancer therapy anthracyclines are often used in
combinations with other chemotherapeutic drugs and agents for molecularly
targeted the... |
25,566 | [Role of Autoantibodies Against 1-Adrenergic Receptor in Cardiovascular
Disease]. | According to current knowledge, autoantibodies against 1-adrenergic receptors
may be involved in pathogenesis of different cardiovascular diseases and are
mostly studied in patients with Chagas disease, dilated cardiomyopathy and heart
rhythm disorders. They may play an important role in cardiomyocyte apoptosis,
al... |
25,567 | [Free Radical Processes Play an Important Role in the Etiology and Pathogenesis
of Atherosclerosis and Diabetes]. | In this review, we present with exhaustive completeness the data of foreign
studies and results of many years of own research, evidencing of the important
role of free radical processes in the etiology and pathogenesis of
atherosclerosis. The review contains the rationale for the concept that
oxidative stress in at... |
25,568 | [Transaortic Implantation of Aortic Valve Bioprosthesis in High-Risk Patient
With Simultaneous Off-Pump Coronary Artery Bypass Grafting]. | Transaortic approach represents an alternative variant of transcatheter aortic
valve implantation (TAVI) which combines benefits of antegrade transapical
approach and high safety profile characteristic of transfemoral approach. This
method has substantial advantages over subclavian and transapical approaches in
cas... |
25,569 | [Causes of Angina Pectoris in Survivors of Myocardial Infarction and the Role of
Optimization of Antianginal Therapy. Data of the LINKOR Study E..]. | AIM: to analyze causes of attacks of angina pectoris and assess impact of
optimization of antianginal therapy on frequency of attacks provoked by various
factors.
MATERIAL AND METHOD: We analyzed diaries of 1226 survivors of myocardial
infarction (MI) which occurred within 12months before inclusion in the LINKOR
pr... |
25,570 | [Assessment of the Impact of Nicorandil on the Quality of Life and Prognosis
Indicators in Patients With Stable Angina]. | OBJECTIVE: To study the effect of nicorandil on the elasticity of the great
vessels, cardiac functional parameters and quality of life in patients with
coronary heart disease (CHD).
MATERIAL AND METHODS: In a double-blind, randomized, placebo-controlled trial of
nicorandil was attended by 154 patients with stable an... |
25,571 | [A Single Preventive Counseling in the Hospital Does Not Improve the Prognosis
of Patients After Percutaneous Coronary Intervention]. | The purpose of the study "Invasive Techniques for the treatment of
atherosclerosis: the effectiveness of secondary preventive intervention"
(IMLA-TRAC) - long-term efficacy of single preventive counseling of patients
with coronary heart disease (CHD) in a stationary treatment for percutaneous
coronary intervention ... |
25,572 | [Effects of Amlodipine/Lisinopril Fixed-Dose Combination on Severity of Left
Ventricular Hypertrophy and Parameters of Myocardial Stiffness in Patients With
Hypertension]. | AIM: To assess effects of 12 weeks treatment with the amlodipine/lisinopril
fixed-dose combination (ALFDC) on the left ventricular (LV) mass index (LVMI),
parameters of LV and left atrial stiffness.
METHODS: At phase 1 of the study we examined 44 healthy subjects (21 men, 23
women, mean age 51.5+/-1.0 years) and 60 ... |
25,573 | [Diagnosis, Prognosis, Monitoring of Cardiac Complications of Arterial
Hypertension. Hypertensive Heart Disease]. | AIM: of the study was further investigation of diagnostics and management of
cardiac complications of essential hypertension (EH).
METHODS: Retrospective analysis of annual reports of cardiological departments
for 10 year period was carried out. Internists (n=330) from 6 regions of Russia
participated in the study. ... |
25,574 | [Antihypertensive Therapy and its Efficacy in Outpatient Elderly and Very
Elderly Subjects]. | PURPOSE OF THE STUDY: The study of the characteristics and effectiveness of
antihypertensive therapy (AHT) in patients aged 65 years and older.
MATERIAL AND METHODS: The study included 356 patients, mean age 74,9+/-6,1
years, 80.4% women. The prevalence of arterial hypertension (AH) and the current
intake of antihyp... |
25,575 | [Volume of Coronary Artery Bypass Surgery and Risk of Postoperative Atrial
Fibrillation]. | PURPOSE: To identify prevalence of atrial fibrillation (AF) in dependence of
volume of coronary artery bypass grafting (CABG) as assessed by the number of
grafts.
MATERIAL AND METHODS: The study included 431 patients with ischemic heart
disease (IHD) who underwent CABG. Group 1 comprised patients with single-vessel ... |
25,576 | [Detection of Autoantibodies Against the 1-Adrenergic Receptor in the Sera of
Patients via the Competitive cell-Based Enzyme Linked Immunosorbent Assay]. | OBJECTIVE: This study aimed to assess the level of anti-1-adrenergic receptor
autoantibodies in patients with ventricular arrhythmias with no signs of organic
heart disease and with presence of cardiovascular pathology in comparison with a
group of healthy volunteers.
MATERIAL AND METHODS: The study included 44 pati... |
25,577 | [Immunological Analysis of Human Atherosclerotic Plaques in ex vivo Culture
System]. | THE AIM OF THE STUDY: to analyze the dynamics of lymphocytic composition of
human atherosclerotic plaques in ex vivo culture system.
MATERIALS AND METHODS: The study included 15 atherosclerotic plaques obtained
from patients who underwent carotid endarterectomy. Plaques were cultured as
ring-shaped explants on colla... |
25,578 | [Prevalence of Risk Factors of Non-Communicable Disease in Kyrgyzstan:
Assessment using WHO STEPS Approach]. | Assessment of prevalence of risk factors for non-communicable diseases (NCD)
based on WHO "STEPS" approach was conducted in Kyrgyzstan. Results of this study
demonstrated high prevalence of NCD risk factors: 94.2% of subjects aged 24-64
years had risk factors. Prevalence of elevated blood pressure was 48.7, smoking ... |
25,579 | [Assessment of the Possibility of Comparing Mortality Rates from Diseases of the
Circulatory System in the United States and Russia]. | OBJECTIVE: to compare and discuss causes of differences between standardized
mortality rates (SMR) from diseases of the circulatory system (DCS) among men
and women older than 50 years in Russia and USA.
MATERIAL AND METHODS: Data on mortality rate in the USA were taken from WHO
mortality database (WHO MD), those on... |
25,580 | [Five Year Dynamics of Main Clinical Symptoms in Patients With Ischemic Heart
Disease in Russia in Comparison With Other Countries (the CLARIFY Registry)]. | The CLARIFY register (The prospeCtive observational LongitudinAl RegIstry oF
patients with stable coronary arterY disease) combined data of outpatients with
stable coronary artery disease (CAD) from 45 countries including Russia. Purpose
of this publication was to analyze dynamics of stable angina during 5 years of ... |
25,581 | [Efficacy of Home-Based Exercise Training and Adherence to Therapy in Patients
After Coronary Artery Bypass Grafting]. | AIM: to assess efficacy of home-based exercise training (HBET) at outpatient
stage of cardiac rehabilitation and its impact on adherence to treatment in
patients after coronary artery bypass grafting (CABG).
MATERIAL AND METHODS: In 1 month after CABG 112 male patients (after completion
of rehabilitation program in ... |
25,582 | [Efficacy and Safety of a Fixed Combination of Perindopril Arginine and
Amlodipine in Patients With Hypertension Uncontrolled by Treatment With
Angiotensin II Receptor Blockers in Real Clinical Practice. Results of the
PREVOSHODSTVO (SUPERIORITY) Program]. | The article presents preliminary results of a subanalysis of PREVOSHODSTVO
(SUPERIORITY) phase IV study. Aim of this subanalysis was to assess efficacy and
tolerability of a fixed-dose perindopril/amlodipine combination (FDPAC) in
patients with arterial hypertension (AP) uncontrolled on previous treatment with
angi... |
25,583 | [Computed Tomography in the Evaluation of Coronary Atherosclerotic Plaques:
Comparison With Intravascular Ultrasound]. | PURPOSE: Determination of computed tomography angiography (CTA) informativeness
in assessment of state of atherosclerotic coronary plaque (ACP) and
identification of signs of its instability compared with intravascular
ultrasound (IVUS).
MATERIALS AND METHODS: Coronary CTA was carried out in 52 patients with clinica... |
25,584 | [Soluble Suppression of Tumorogenicity 2 Increases Opportunities for Risk
Stratification After Acute Heart Failure Decompensation]. | PURPOSE: to evaluate the significance of soluble ST2-receptor (sST2)
concentrations in patient (pts) risk stratification in with acute decompensated
heart failure (ADHF) during long-term follow-up period.
METHODS: In the prospective single-center study were included 159 pts with ADHF
III-IV FC NYHA. Blood samples to... |
25,585 | [The Time Course of Formation Of Systolic Dysfunction of the Heart in
Doxorubicin Cardiomyopathy]. | The anthracycline-induced cardiomyopathy is a frequent and menacing complication
of antitumor therapy leading to chronic heart failure. A study of the formation
of heart failure can reveal early signs of the development of systolic
dysfunction of the heart. In this work in rats we studied cardiac function at
differ... |
25,586 | [The Course of Pregnancy in Women With Arterial Hypertension]. | We included in this study 69 women with hypertension in the II trimester of
pregnancy, of whom 52 (75%) had normal weight gain during the period of
gestation, and 17 (25%) had abnormal weight gain. Comprehensive clinical and
instrumental examination included calculation of body mass index before and
during gestatio... |
25,587 | [Problems and Perspectives of Echocardiographic Evaluation of the Left
Ventricular Diastolic Function]. | This literature review is devoted to noninvasive evaluation of the left
ventricular (LV) diastolic function by echocardiography with special stress on
existing problems of detection of LV dysfunction by Doppler echocardiography of
transmitral blood flow. Basing on existent algorithms one often cannot clearly
judge ... |
25,588 | [The Choice of Anticoagulant Therapy in Patients With Non-Valvular Atrial
Fibrillation and Chronic Kidney Disease]. | The review shows the prevalence of atrial fibrillation (AF) in patients with
chronic kidney disease (CKD), depending on the severity of the disease. Patients
with non-valvular AF and CKD have a significantly increased risk of both
bleeding and thromboembolic complications, and death from all causes. Evaluation
of t... |
25,589 | [Ischemic Heart Disease: Focus on Acute Infarction of the Right Ventricular
Myocardium]. | Ischemic heart disease and acute myocardial infarction (AMI) in particular
remain widely spread and contribute seriously in total mortality of population.
This literature review is devoted to the right ventricular (RV) AMI as the least
studied problem of contemporary cardiology. We present here description of
speci... |
25,590 | [Elevated Lipoprotein(a) Cncentration and Presence of Subfractions of Small
Dense Low Density Lipoproteins as Independent Factors of Risk of Ischemic Heart
Disease]. | AIM: To study relation of lipoproteina - Lp(a) and subfractional composition of
apoB containing lipoproteins to the presence of ischemic heart disease (IHD).
Manerial and methods. Parameters of lipid spectrum, Lp(a), and subfractions of
apoB containing lipoproteins were determined in blood serum of 187 patients with... |
25,591 | [Novel Scale for Long-Term Prognostication of Risk of Death and Nonfatal
Cardiovascular Complications in Patients From the PROGNOSIS-IHD Registry]. | PURPOSE: To elaborate a risk score for prognostication of long-term survival of
patients with chronic ischemic heart disease (CIHD) using data of the
PROGNOSIS-IHD Registry.
MATERIAL AND METHODS: Participants of the PROGNOSIS-IHD Registry (n=641, 500
men, 141 women) were inhabitants of Moscow region consecutively ad... |
25,592 | [Serial Assessment of Transthoracic Coronary Flow Reserve as Method of Assessing
Efficacy of Intracoronary Intervention in the Left Anterior and Posterior
Descending Arteries]. | Transthoracic echocardiography (TTE) has been described as an accurate technique
for noninvasive evaluation of coronary flow reserve (CFR) of the left anterior
descending artery (LAD) and posterior descending artery (PDA). Aim of this study
was to find out whether serial measurement of CFR in LAD and PDA using TTE
... |
25,593 | [Influence of the Potassium Channels Activator Nicorandil to the Quality of Life
in Patients With Ishemic Heart Disease and Stable Angina Pectoris]. | The aim of the study to assess the influence of medicamentous therapy to the
quality of life of ischemic heart disease patients with stable angina pectoris
by activator potassium channels nicorandil in comparison with traditional
therapy by isosorbide dinitrate. The study included 84 ischemic heart disease
patients... |
25,594 | [Long-Term Survival After Myocardial Infarction]. | The purpose of this study was to explore the long-term survival of patients
after myocardial infarction (MI) and to elucidate main medical and social
factors affecting survival.
MATERIAL AND METHODS: In 2006 we included into this study 791 consecutive
patients with MI. Duration of follow-up was 8.5 years. Survival w... |
25,595 | [Assessment of Efficiency of Medicamentous Therapy in Correction of Structurally
Functional Changes of The Cardiac Muscle at Patients With Arterial Hypertension
in Combination With Bronchial Asthma]. | BACKGROUND: Bronchial asthma (BA) is a serious problem. It was found that the
frequency of arterial hypertension (AH) detection in patients with asthma is
about 30 %. At patients practically all types of violations of a warm rhythm
meet a bronkhoobstruktivny syndrome. Emergence of rather new preparations -
If-block... |
25,596 | [Galectin-3 in Patients With Paroxysmal and Persistent Atrial Fibrillation and
Metabolic Syndrome]. | OBJECTIVE: To evaluate serum galectin 3 and to determine the potential clinical
value of this parameter in patients with atrial fibrillation - AF (paroxysmal
and persistent) and metabolic syndrome (MS).
DESIGN AND METHODS: We examined 100 patients with MS (50 with paroxysmal or
persistent AF and 50 without arrhythmi... |
25,597 | [Comparative Analysis of the Efficacy and Safety of Rosuvastatin and Original
Rosuvastatin]. | The study is one of the priority points of the Russian Scientific Medical
Society of Internal Medicine, initiated due to known high average level of LDL
cholesterol in Russian population and necessity for its optimized control by
better access to treatment.
AIM: To conduct comparative analysis of efficacy and safety... |
25,598 | [Autoimmunity and Prognosis of Patients With Morphologically Documented
Myocarditis]. | AIM: to assess clinical and prognostic value of circulating cardiospecific
autoantibodies (AAB) and CD4+ T-regulatory cells in patients with myocarditis.
MATERIAL AND METHODS: We included into this study 47 patients with lymphocytic
myocarditis verified by analysis of histological and immunohistochemical data.
Compa... |
25,599 | [Cardiovascular Complications of Rheumatoid Arthritis: Prevalence and
Pathogenesis]. | Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with high
risk of cardiovascular events. Among main causes of death in RA are: myocardial
infarction, cerebrovascular accident, sudden cardiac death, which are determined
by the early development and rapid progression of atherosclerotic vascular ... |
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