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25,600 | [Problems of Determination of Degree of Disability After Coronary Artery Bypass
Surgery]. | The review contains data on rates of permanent loss of working ability
(disability) after coronary artery bypass grafting (CABG) in Russia and in
European populations of patients with ischemic heart disease. According to
domestic studies determination of disability status is not based on assessment
of objective cha... |
25,601 | [Chronic Heart Failure With Preserved Systolic Function and Reversible
Dilatation of Cardiac Chambers]. | Diagnosis of dilation (D) cardiomyopathy (CMP) requires exclusion not only of
inflammatory and genetically determined forms but also of some rare diseases.
This 51 year old patient with history of moderate arterial hypertension
approached a cardiologist because of new onset atrial fibrillation and dyspnea.
Echocard... |
25,602 | [Association of I/D and -786 Polymorphisms of ACE and NOS3 Genes With Features
of the Course of Ischemic Heart Disease and Diabetes Mellitus Type 2]. | AIM: to study relationship of ACE insertion-deletion (I/D) polymorphism and NOS3
T-786C polymorphism with characteristics of the course of ischemic heart disease
(IHD) at the background of diabetes mellitus.
MATERIALS AND METHODS: Were examined 114 patients with IHD, 29.8% of patients
had type 2 diabetes mellitus. A... |
25,603 | [Left Bundle Branch Block in Unstable Angina. Mortality and Rate of Myocardial
Infarction]. | AIM: to study mortality and adverse outcomes in patients with unstable angina
(UA) and left bundle branch block (LBBB).
MATERIAL AND METHODS: We included in this study UA patients with (n=56) and
without LBBB (n=310). Period of observation was 14 days (from admission to
discharge). The following events were consider... |
25,604 | [Prognostic Significance of Erythropoietin in Patients With Acute Coronary
Syndrome]. | AIM: to investigate the prognostic role of erythropoietin (EPO) in patients with
acute coronary syndrome (ACS).
MATERIAL AND METHODS: Eighty-four patients (46 men, 38 women, mean age 63+/-11
years) with ACS were studied. Twenty-one patients had ST-elevation myocardial
infarction (STEMI), 12 - non-ST-elevation myocar... |
25,605 | [In-hospital Outcomes and Complications of Percutaneous Coronary Interventions
in Acute ST-Elevation Myocardial Infarction in Different Age Groups]. | AIM: to assess early (in-hospital) results of percutaneous coronary intervention
(PCI) for ST-elevation (STE) myocardial infarction (MI) in different age groups.
MATERIALS AND METHODS: We enrolled in this study 356 patients with STEMI who
underwent PCI within 24 hours of the disease during 1 year (2012). According to... |
25,606 | [Histochemistry of Coronary Arteries in Myocardial Infarction]. | In this study we used the samples of autopsy material from 15 patients who died
of myocardial infarction. As control we used autopsy material from 5 victims of
car accidents. Quantitative comparison of area of coronary arteries of healthy
persons and patients with myocardial infarction revealed its decrease in
pati... |
25,607 | [The Effectiveness of Combination Antihypertensive Therapy in Women With
Hypothyroidism and the Metabolic Syndrome]. | PURPOSE OF THE STUDY: Evaluating the effectiveness of the various options of
combination antihypertensive therapy (AHT) in women with arterial hypertension
(AH) and metabolic syndrome (MS) and hypothyroidism.
MATERIAL AND METHODS: The study included 163 women with hypertension, metabolic
syndrome, and hypothyroidism... |
25,608 | [Psychological Characteristics of Patients With Stress-induced Arterial
Hypertension: a Violation of the Regulation of Emotions as a Central Link of
Pathogenesis]. | GOAL: The study of emotional and personality characteristics of patients with
hypertension in the workplace (HW) and comparative assessment of the
effectiveness of antihypertensive therapy in these patients.
MATERIAL AND METHODS: The study included 170 patients c hypertensive disease
stage II, 1-2-th degree, aged 32... |
25,609 | [Factors Associated With Development of Atrial Fibrillation After Coronary
Artery Bypass Grafting]. | PURPOSE: to identify factors associated with development of atrial fibrillation
(AF) in the early postoperative period of coronary artery bypass grafting
(CABG).
METHODS: A total of 376 patients with ischemic heart disease who underwent CABG
were enrolled in the study.
RESULTS: During the observation period AF occur... |
25,610 | [Chronic Reno-Cardial Continuum in Glomerulonephritis]. | OBJECTIVES: To elucidate main risk factors contributing to development of
cardiovascular pathology at the predialysis stage of chronic glomerulonephritis.
MATERIALS AND METHODS: We examined 173 patients (90 men, 83 women, age 15-70,
mean age 36.8+/-12.9 years) at predialysis stage of chronic glomerulonephritis.
Card... |
25,611 | [Is it Possible to Improve Results in the Conservative Treatment Strategy in
Patients With Acute Coronary Syndrome?]. | Almost 60% of patients with acute coronary syndrome (ACS) without ST segment
elevation are not subjected to revascularization procedures. This review
analyzes the reasons for the choice of the conservative tactics of patients with
ACS. The possibilities of improving outcomes by using modern medicines.
Particular at... |
25,612 | [The Importance of Perfusion Assessment for Determination of Functional
Sufficiency of Myocardium]. | Myocardial vascular bed is represented by a network of arterial and venous
vessels as well as microcirculatory vessels including arterioles,
precapillaries, capillaries, postcapillaries, venules, and arteriolo-venular
anastomoses. Myocardial capillaries are an exchange link providing perfusion of
the myocardium wit... |
25,613 | [Selection of Diuretic Therapy in Cardiology Practice]. | Diuretic drugs - one of the most frequently prescribed groups of drugs in
cardiology practice, primarily in patients with arterial hypertension (AH) and
chronic heart failure (CHF). The article discusses the features of thiazide and
loop diuretics, questions the selection of individual representatives of this
class... |
25,614 | [Chronic Heart Failure Due to Formation of Giant Left Ventricular Pseudoaneurysm
After Painless Myocardial Infarction in a Female Patient With Diabetes]. | Rupture of the free wall of the left ventricle with the formation of a false
aneurysm (pseudoaneurysm, PA) - is a rare complication of acute myocardial
infarction. Given the high risk of rupture of the PA and other life-threatening
consequences (progressive heart failure, thromboembolic events), as well as the
abse... |
25,615 | [The Impact of Asymptomatic Left Ventricular Dilatation on the Course of
Anterior Myocardial Infarction.]. | AIM: to elucidate effect of asymptomatic left ventricular (LV) dilatation on the
course of myocardial infarction (MI).
MATERIAL AND METHODS: LV remodeling and diastolic function, as well as inter-
and intraventricular asynchrony were studied in 58 patients with primary
anterior MI without signs of heart failure and ... |
25,616 | [Clinical and Economic Aspects of Meldonium as Part of Physical Rehabilitation
Programs in Patients With Coronary Heart Disease After Percutaneous Coronary
Interventions]. | PURPOSE: to analyze clinical and economical effectiveness of meldonium as
component of integrated program of cardio-rehabilitation in patients with
ischemic heart disease (IHD) in the early period after percutaneous coronary
intervention (PCI) with incomplete revascularization.
MATERIAL AND METHODS: A program of con... |
25,617 | [Circadian CLOCK Gene Variants, Parameters of Arterial Stiffness and Blood
Pressure Levels in Subjects Without Arterial Hypertension]. | CLOCK gene polymorphic variants, parameters of arterial stiffness and blood
pressure (BP) variability were studied in 115 normotensive Russian patients
without cardiovascular diseases (62 men, 53 women; mean age 36.4+/-1.01 years).
Examination included ECG, 24h BP monitoring, duplex scan of carotid arteries,
regist... |
25,618 | [Dynamics of Biochemical Markers of Endothelial Dysfunction in Patients With
Arterial Hypertension]. | Arterial hypertension (AH) occupies the first place among causes of atrial
fibrillation (AF) in general population. AF in patients with AH substantially
elevates risk of cardiovascular complications. Endothelial dysfunction (ED) in
patients with AH at appearance of AF might have great prognostic value for
stratific... |
25,619 | [Immediate Outcomes of Coronary Artery Bypass Grafting in Patients With
Multifocal Atherosclerosis: Gender Differences]. | AIM: To assess the impact of presence of multifocal atherosclerosis (MFA) and
gender differences on immediate outcomes after coronary artery bypass grafting
(CABG) in patients with ischemic heart disease (IHD).
MATERIAL AND METHODS: Medical records of patients with MFA, who underwent
elective CABG (n=764, 655 men, 1... |
25,620 | [Adipokines Level in Metabolically Healthy Obese Saint-Petersburg Inhabitants
(ESSE-RF)]. | AIM: to elucidate prevalence of phenotypes of metabolically heathy obesity (MHO)
among inhabitants of Saint-Petersburg using various criteria and assess
dependence levels of adipokines on obesity phenotype.
MATERIAL AND METHODS: Within a framework of epidemiologic study ESSE-RF we
formed a random sample of 1600 Sain... |
25,621 | [Treatment of Patients With Atrial Fibrillation: the Search for Optimal
Solutions]. | Atrial fibrillation (AF) - the most common arrhythmia in clinical practice,
impair the quality of life significantly increases morbidity and mortality.
Current methods of treatment of patients with AF, except anticoagulant therapy
hitherto failed to provide significant improvement in cardiovascular events are
of li... |
25,622 | [A Review of Recent European Clinical Guidelines: What Useful for the
Practitioner?]. | This review article provides an outline of 5 of the updated clinical practice
guidelines of the European Society of Cardiology developed by leading experts of
the relevant working groups of the society. Guidelines deal with new approaches
to identification, diagnosis, treatment and prevention of pericardial diseases... |
25,623 | [The New European Questionnaire for Assessment of Quality of Life of Patients
With Ischemic Heart Disease: HeartQoL]. | Quality of life (QL) of patients with ischemic heart disease (IHD) is a
combination symptoms of the disease, physical state, emotional status, and
social-laboring functioning. Until recently there were no universal
questionnaire allowing to perform comparative analysis of QL of patients with
effort angina (EF), sur... |
25,624 | [The Insufficiency Type of Metabolic Balance and Nutritional Status in Patient
With Heart Failure]. | A lot of data has been accumulated at present on the metabolic and nutritional
insufficiency in patients with chronic heart failure (CHF). Researchers have
noted an actuality of the study of nutritional and metabolic insufficiency in
CHF patients as independent factors affecting the course of CHF and because of
its... |
25,625 | [Rivaroxaban at Non-Valvular Atrial Fibrillation: a Prospective Study and
Clinical Practice]. | The article presents an analytical review of the results of post-registration
clinical studies on the efficacy and safety of rivaroxaban in nonvalvular atrial
fibrillation (AF) to prevent stroke and other systemic thromboembolic
complications. The main purpose of the first large prospective international
observatio... |
25,626 | [Platelet Metabolism in Clopidogrel Resistant and Sensitive Patients With
Ischemic Heart Disease]. | OBJECTIVE: to investigate relationship between activity of platelet nicotinamide
adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate
(NADP) dependent dehydrogenases in patients with ischemic heart disease (IHD)
after coronary artery bypass grafting (CABG) and their sensitivity to
clopidogrel.... |
25,627 | [Factors Associated With Immediate Results of Coronary Artery Bypass Grafting in
Patients With Ischemic Heart Disease in the Presence of Type 2 Diabetes]. | OBJECTIVE: to elucidate factors associated with cardiovascular events (CVE)
after coronary artery bypass grafting (CABG) depending on the presence of type 2
diabetes mellitus (DM2).
MATERIAL AND METHODS: Medical records of 667 patients who underwent CABG during
the period from 2006 to 2009 (317 patients with and 350... |
25,628 | [The Role of Urinary Lipocalin in Prognostication of Hospital Complications in
Patients With Ischemic Heart Disease After Coronary Artery Bypass Grafting]. | PURPOSE: To assess significance of urinary neutrophil gelatinase-associated
lipocalin (NGAL) for predicting hospital complications in subjects with ischemic
heart disease (IHD) after coronary artery bypass grafting (CABG).
MATERIALS AND METHODS: The study included 720 subjects who underwent CABG
between 03/2011 and ... |
25,629 | [Comparative Assessment of Antianginal Efficacy and Safety of Nicorandil at the
Background of Therapy With -Adrenoblockers in Ischemic Heart Disease Patients
With Stable Angina]. | AIM: to demonstrate impact of addition of nicorandil to standard treatment in
patients with stable ischemic heart disease (IHD) on clinical manifestations of
the disease and safety of conducted therapy.
MATERIAL AND METHODS: We included in this double-blind placebo controlled study
with parallel groups 120 patients ... |
25,630 | [Hronotherapy Aspects of Efficiency Azilsartan Medoxomil in Combination Therapy
in Patients With Hypertension and Metabolic Syndrome]. | OBJECTIVE: Determination of the effectiveness and safety of different dosing
regimens during the day (in the morning or at bedtime) combination therapy
including azilsartan medoxomil in patients with essential hypertension and
metabolic syndrome (MS).
DESIGN AND METHODS: The study included 60 patients with uncontrol... |
25,631 | [Clinical and Ultrasonographic Characteristics of Women With Gestational
Hypertension]. | We studied clinical and ultrasonographic parameters in pregnant women - 183 with
and 152 without gestational arterial hypertension (GAP). Characteristics of
women with GAP were as follows: age 16-45 years, mean age 27.9+/-4.7 years,
disease duration 8.8+/-4.0 weeks, mean systolic and diastolic blood pressure at
ini... |
25,632 | [Hemodynamic Predictors of Clinical Deterioration in Patients With Pulmonary
Arterial Hypertension Associated With Systemic Scleroderma]. | OBJECTIVE: to elucidate hemodynamic predictors of clinical deterioration (CD) in
patients with pulmonary arterial hypertension (PAH) associated with systemic
scleroderma (SSD).
MATERIAL AND METHODS: We included into this study 48 patients with PAH-SSD
consecutively admitted in 2004-2014. At inclusion all patients un... |
25,633 | [The Brugada Syndrome as a Cause of Sudden Death. Diagnostics and Clinical
Manifestations in Children]. | The Brugada syndrome is a hereditary potentially arrhythmogenic disease related
to the category of channelopathies. It is manifested as syncopal states and
sudden death in young people in the absence of structural cardiac disease. The
basis of the disease is genetically determined abnormality of function of ionic
c... |
25,634 | [Renoprotecion With Metabolic Syndrome: the Possibility of Receptor Agonist
Imidazoline Moxonidine]. | The article is devoted to the of prevalence, diagnosis, and prognostic
significance of renal damage in metabolic syndrome. The pathogenetic mechanisms
of development and progression of chronic kidney disease in individuals with
obesity, including the role of increased activity of the sympathetic nervous
system is d... |
25,635 | [Availability of Potassium and Magnesium Ions is a Fundamental Condition for the
Maintenance of Normal Blood Pressure]. | Administration of preparations of potassium and magnesium to patients with
arterial hypertension is an accepted therapeutic practice. In this paper we
examine relationships between the content of potassium and magnesium in the body
and levels of arterial pressure. Results of relevant fundamental and clinical
studie... |
25,636 | [Ability to Overcome the Thrombocyte Resistance to Acetylsalicylic Acid in
Patients With Coronary Artery Disease After Myocardial Revascularization With
Coronary Stenting]. | Resistance to acetylsalicylic acid (ASA) in patients with coronary artery
disease is a poor predictor for the development of atherothrombotic
complications. In 277 patients with coronary artery disease suffered
uncomplicated coronary angioplasty with stent implantation, we was estimated
arachidon-induced platelet a... |
25,637 | [Interaction Between Personality, Pain, and Genes in Ischemic Heart Disease]. | Personality traits of the patient with ischemic heart disease (IHD) are thought
to determine disease course. Their level depends on clinical presentations of
IHD including the presence of cardiac pain. The aim of the study was to identify
the modifying effect of genes coding for serotonin transporter (5-HTTLPR),
se... |
25,638 | [Stable Nitric Oxide Metabolites Levels in Hypertensive Patients With Obesity
and High Leptin Level]. | OBJECTIVE: to investigate levels of the stable nitric oxide metabolites (NOx) in
hypertensive patients with obesity and hyperleptinemia.
MATERIAL: We examined 124 untreated patients (45 men and 79 women) with
essential hypertension (EH) (mean age 51.4+/-6.5 years, mean hypertension
duration 8.5+/-7.6 years, 64% with... |
25,639 | [Desadaptive Reaction and Development of Arterial Hypertension in Conditions of
Professional Stress]. | PURPOSE: to compare prevalence of maladaptive responses and risk of hypertension
and cardiovascular remodeling.
MATERIAL AND METHODS: We examined using clinical and instrumental methods 1321
workers of locomotive crews; 472 of those examined were followed-up for 12
years.
RESULTS: Machinists with maladaptive respons... |
25,640 | [Therapy of High Risk Patients After Decompensation of Heart Failure Under
NT-proBNP Control. Main Results]. | AIM: to compare efficacy of treatment of high risk patients after acute
decompensation (AD) of chronic heart failure (CHF) based on monitoring of
NT-proBNP concentration and standard treatment.
MATERIAL AND METHODS: Patients (n=100) with class III-IV CHF and left
ventricular ejection fraction (LV EF) <40% due to isc... |
25,641 | [Bone Metabolism and Mineral Density in Chronic Heart Failure]. | PURPOSE: to assess the state of bone metabolism and mineral density in
outpatients with chronic heart failure (CHF).
MATERIAL AND METHODS: We examined 70 outpatients (30 men, 40 women, aged 56-88
years) with CHF and 40 outpatients without CHF (10 men, 30 women, aged 57-88
years). Examination included laboratory asse... |
25,642 | [Combination of Visual and Metabolic Markers in Assessment of Probability of
Presence and Severity of Atherosclerosis of Coronary Arteries]. | AIM: to assess possibilities of the use of biochemical markers combined with
data of methods of imaging of arterial atherosclerotic lesions for evaluation of
risk of presence and severity of coronary atherosclerosis.
MATERIALS AND METHODS: We enrolled into this study patients (n=205, 136 men, 69
women, age 33-85 yea... |
25,643 | [Coronary Angioplasty and Stenting in Patients Older Than 80 Years: Immediate
and Long-Term Results]. | AIM: to assess immediate and long-term results of coronary angioplasty and
stenting in patients older than 80 years - a high risk group in view of the
severity of concomitant pathology and extent of coronary atherosclerosis.
MATERIAL AND METHODS: We conducted retrospective analysis of data from 167
patients older th... |
25,644 | [Prevalence of Hypertriglyceridemia: New Data Across the Russian Population. The
PROMETHEUS Study]. | STUDY AIM: The main purpose of the study was to estimate prevalence of subjects
with hypertriglyceridemia (HTG) in Russia. Secondary objectives were to explore
HTG prevalence by levels, age and sex, and to assess correlation between
glycated hemoglobin (HbA1C) and triglyceride (TG) level. Additionally, we
analyzed ... |
25,645 | [The Results of the Method Percutaneous Intracoronary Intervention in Patients
of Both Male and Female]. | OBJECTIVE: To assess gender differences among patients subjected to percutaneous
coronary intervention (PCI) according to data of the "Register of performed
operations of percutaneous transluminal coronary angioplasty (PTCA)".
MATERIALS AND METHODS: The Register was conducted from 1996 to 2012 years and
comprised 48... |
25,646 | [Influence of Type D Personality on Adherence to Treatment in Cardiac Patients]. | AIM: of the study was to examine relationship between behavioral type D and
adherence to therapy in cardiological patients.
MATERIAL AND METHODS: Patients (n=308, 63 [20.5%] women and 245 [79.5%] men,
mean age 59+/-4 years) with stable ischemic heart disease and arterial
hypertension were divided into 2 groups: with... |
25,647 | [Nonplatelet Effects of Ticagrelor]. | This review summarizes current knowledge concerning "nonplatelet effects of
P2Y12 receptor antagonist ticagrelor. We show the experimental and clinical
evidence that ticagrelor increases plasma concentration of adenosine as a
potential mechanism of additive effects of ticagrelor. In addition, we sought to
compare t... |
25,648 | [Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction
With ST-Segment Elevation After Prehospital Thrombolysis]. | PURPOSE: to analyze results of percutaneous coronary intervention (PCI) in
patients with acute ST- elevation myocardial infarction performed after
prehospital thrombolysis in real clinical practice.
MATERIAL: In the period from 2008 to 2013 144 and 577 patients were subjected to
PCI after prehospital thrombolysis wi... |
25,649 | [The Study of Associations of Polymorphisms of Candidate Gene of Cardiovascular
Diseases With Reduction of Glomerular Filtration Rate in Patients With ST
Segment Elevation Myocardial Infarction]. | AIM: to study associations of polymorphic genetic variants of inflammatory
response, endothelial function, lipid metabolism, and blood coagulation with
impaired renal function in patients with ST elevation myocardial infarction
(STEMI).
MATERIAL AND METHODS: We enrolled in the study 171 patients admitted to the
Kem... |
25,650 | [Effectiveness of Dispersible Forms of Perindipril in Patients With Uncontrolled
Arterial Hypertension in Clinical Practice]. | AIM: The study was aimed at evaluating the efficacy and usability of a
dispersible form of perindopril in patients with arterial hypertension (HT) in
clinical practice.
MATERIALS AND METHODS: The study enrolled 52 patients with newly diagnosed or
uncontrolled HT of grade 1-2. The baseline assessment consisted of phy... |
25,651 | [Comparative Evaluation of -blockers and If-Channel Inhibitor in Patients With
Chronic Heart Failure and Preserved Left Ventricular Ejection Fraction]. | Treatment of patients with chronic heart failure (CHF) and preserved left
ventricular (LV) ejection fraction remains largely empirical, as none of the
methods of therapy improves the prognosis of patients. In a prospective
randomized study on 126 patients with CHF and LV ejection fraction more or equal
50% we compa... |
25,652 | [Risk Factors of Recurrent Bleedings at Therapeutic International Normalized
Ratio in Patients on Long-Term Warfarin Therapy]. | AIM: to investigate parameters of fibrinolysis in patients on long-term warfarin
(W) therapy, and assess their relation to the risk of recurrent bleeding
occurring at therapeutic international normalized ratio (INR).
MATERIALS AND METHODS: Our prospective study involved 78 W-naive patients (40
men, age 64.3+/-12.2 y... |
25,653 | [Visceral Obesity as Risk Factor of Early Vascular Aging]. | AIM: to analyze dependence of parameters of vascular remodeling on the presence
of visceral obesity (VO) assessed by echocardiographic measurement of epicardial
fat thickness (EFT).
MATERIAL AND METHODS: We examined 163 asymptomatic normotensive patients (74.8%
men, mean age 45.0+/-5.4 years) with low or moderate ri... |
25,654 | [Immediate and Long-term Results of the First in Russia of IntrocoronaryMetal
Stent in the Coronary Artery]. | The authors present immediate and long term results of the first in Russia
implantation in coronary artery of Palmaz-Shatz metal stent. Indications for
stenting were urgent after complicated dissection as a result of balloon
dilation of discrete bifurcational stenosis of anterior interventricular artery
(IVA). Imme... |
25,655 | [Clinical Case of Severe Heart Failure Treatment, Produced due to the
Development of Arrhythmogenic Cardiomyopathy in a Patient With Permanent
Junctional Reciprocating Tachycardia (Coumels Tachycardia) With Additional Left
Lateral Accessory Pathway]. | Thirty two years old man had history of atrioventricular re-entry tachycardia
(AVRT) with concealed left-lateral accessory pathway (AP), 3-5episodes per year,
30-40 minutes duration without hemodynamic compromise. Two years ago patient
underwent ablation of concealed left lateral AP. After that tachycardia became
m... |
25,656 | [Interrelation of Electrophysiological and Perfusion Changes in Patients With
Left Ventricular Aneurysm]. | The study was aimed at identification of relations between perfusion and
electrophysiological changes in left ventricular (LV) myocardium in patients
with ischemic heart disease (IHD) with postinfarction LV aneurysm and
ventricular tachycardia. The study enrolled 23 patients with the aforementioned
disease. Preoper... |
25,657 | [Registry of Acute Coronary Syndromes RECORD-3. Characteristics of Patients and
Treatment During Initial Hospitalization]. | Acute Coronary Syndrome (ACS) Registries RECORD 1-2 (2007-2001) gave valuable
information on management of ACS patients in Russia. RECORD-3 was carried out in
March-April, 2015. Here we present characteristics of included patients (pts)
and data on their treatment during initial hospitalization.
MATERIAL AND METHODS... |
25,658 | [Relationship Between Blood Serum Galectin and Renal Dysfunction in ST Elevation
Myocardial Infarction]. | AIM: to assess value for inhospital and 1 year prognosis of unfavorable course
of ST-elevation myocardial infarction (STEMI) of blood serum galectin and
markers of renal dysfunction (RD).
MATERIAL AND METHODS: Standard laboratory and instrumental examination,
calculation of glomerular filtration rate using MDRD form... |
25,659 | [Life Threatening Complications in Patients With ST-Elevation Acute Coronary
Syndrome-Dependence on Reperfusion Interventions (Data of Federal Register of
Patients With Acute Coronary Syndrome)]. | AIM: to study rate and type of life-threatening complications (LC) in patients
with ST-Elevation (STE) Acute Coronary Syndrome (ACS) and their relation to
implementation of reperfusion measures.
MATERIAL AND METHODS: Database of the Federal Register of patients with ACS
(FRACS) which functioned from 01/01/2009 to 01... |
25,660 | [Evaluation of Antihypertensive Efficacy and Patient Adherence to Treatment With
the New Formulation Perindopril Arginine (Orally Disintegrating Tablet) in
General Clinical Practice: OPTIMUM Program]. | The purpose of this study was to evaluate the antihypertensive efficacy of
perindopril arginine in the oral dispersible form of tablets, in clinical
practice.
MATERIALS AND METHODS: Post-marketing observational open program OPTIMUM was
carried out from october 2014 to march 2015 year in 48 cities of the Russian
Fed... |
25,661 | [Myocardial and Arterial Stiffness Important Determinant of NT-ProBNP at
Development of Heart Failure in Survivors of Myocardial Infarction]. | AIM: To study diagnostic value of myocardial-arterial stiffness (MAS) as a
determinant of N-terminal pro-brain natriuretic peptide (NT-proBNP) expression
in patients with chronic heart failure (CHF) with ischemic or postinfarction
left ventricular (LV) dysfunction.
MATERIAL AND METHODS: We analyzed 6 months prognosi... |
25,662 | [Coronary Flow Reserve in the Left Anterior and Posterior Descending Arteries as
an Additional Option to Dipyridamole Stress Echocardiography for Detection of
Stenosis]. | AIM: to assess additive diagnostic value of simultaneous evaluation of coronary
flow reserve (CFR) in the left anterior descending (LAD) artery and posterior
descending artery (PDA) during dipyridamole stress echocardiography
(stress-Echo) for detection of LAD and PDA stenoses >50%.
METHODS: 108 in-patients (mean ag... |
25,663 | [Revascularization in Stable Ischemic Heart Disease: Whether to Change the
Approach?]. | Current international guidelines on stable ischemic heart disease (IHD) state
that coronary revascularization is indicated in cases of: limiting ischemic
symptoms while on optimal medical therapy (OMT); high risk coronary anatomy;
high risk stress test result. At the same time, many results supporting these
conclus... |
25,664 | [Thromboxane A2: Mechanisms of Synthesis and Intracellular Signaling System of
Realization]. | One of major complications of ischemic heart disease is myocardial infarction,
which develops as a result of thrombosis at the site of ruptured atherosclerotic
plaque. Platelets activation and aggregation are the key events of this process.
The efficiency of aspirin and/or clopidogrel use is limited by residual plat... |
25,665 | [Coronary Heart Disease at the Patient With Metabolic Syndrome: Strategy of
Antianginal Therapy]. | Fist-line drugs in ischemic heart disease are -adrenoblockers. However there are
cases when comorbidities limit possibilities of their use. In metabolic syndrome
some representatives of this class unfavorably affect insulin sensitivity,
carbohydrate and lipid metabolism. Alternative is to use ivabradine - selective ... |
25,666 | [Treatment of Patients With Stable Ischemic Heart Disease in Real Clinical
Practice in Russia. The CHOICE-2 Program]. | OBJECTIVE: in the framework of an open post-marketing observational national
program CHOICE-2 to assess correspondence between recommendations for management
of patients with stable angina and actual clinical practice, as well as to
assess effect of treatment with cytoprotector trimetazidine on clinical course
of t... |
25,667 | [Comparative Prospective Clinical Economic Study of Original and Generic
Bisoprolol in Patients With Coronary Heart Disease]. | PURPOSE: to conduct comparative clinical and economical analysis of original and
generic preparations of bisoprolol.
MATERIALS AND METHODS: The study included 61 patients after acute coronary
syndrome (ACS) (34 men, 27 women, age 46-78 years). Patients were distributed
(envelope method) to 2 groups. Patients of grou... |
25,668 | [Rosuvastatin in Coronary Bypass Surgery: Whether Only Secondary Prevention?]. | BACKGROUND AND AIM: The increasing number of coronary artery bypass grafting
(CABG) is associated with a need for active introduction of methods improving
immediate and long-term results of these interventions. Results of a number of
studies conducted during recent years allow to consider high dose statin therapy
o... |
25,669 | [Changing Clinical Presentation of Acute Coronary Syndrome in Patients With
Chronic Obstructive Pulmonary Disease]. | OBJECTIVE: to determine clinical features of acute coronary syndrome (ACS) in
patients with chronic obstructive pulmonary disease (COPD).
METHODS: We included into this study 272 patients with ACS, 110 with and 162
without concomitant COPD. In both groups we registered prevalence of atypical
forms of ACS debut, seve... |
25,670 | [Pleotropic Effects of Atorvastatin in Patients With Chronic Ischemic Heart
Disease]. | Examined 52 patients with a diagnosis Ischemic heart disease: stable angina
II-III FC CHF I-IIA stage, in combination with hypercholesterolemia aged 53-65
years (58,2+/-6,5), receiving together with traditional antianginal therapy
generic atorvastatin Torvakard in the dose of 10 mg/day (20 people) with the
level of... |
25,671 | [Search for an Optimal Formula for Calculation of the Corrected QT Interval in
Children Based on Data of Clinical-Epidemiological Study]. | The aim of the study was to compare different types of QT correction, establish
age norms of QT duration, and assess associations between QT duration and heart
rate (HR) in children. The sample comprised 0-18-year-old children (n=5909)
selected from general population. The study examined several existing formulas
o... |
25,672 | [Efficiency of Operation Trombendarterektomy From Pulmonary Artery Branches
Depending on the Degree of Pulmonary Hypertension and Duration of Disease]. | AIM: to assess effect of thromboendarterectomy from pulmonary artery branches on
clinical functional state of patients with chronic thromboembolic pulmonary
hypertension (CTEPH) in dependence on degree of pulmonary hypertension and
disease duration.
MATERIAL: Patients (n=152) were divided into 3 groups: (1) with sys... |
25,673 | [Myocardial Infarction and Natural Defense Mechanisms: The Role of
Norepinephrine Reuptake]. | PURPOSE: to study effect of norepinephrine reuptake blockade in reperfusion
period on size of infarct caused by local ischemia with and without ischemic
pre- and postconditioning.
MATERIAL AND METHODS: Wistar rats (n=46) were randomly divided into 6 groups.
Group (gr) I (n=7) - 30 min occlusion of left coronary arte... |
25,674 | [Results of Monitoring of the Plan of Measures Directed to Reduction of Ischemic
Heart Disease in North Caucasus Republics. Analysis of Dynamics of
Cardio-Vascular Mortality]. | Comparative analysis of dynamics of cardiovascular mortality in Russia and
foreign countries as well as main directions of development of cardiological
service in Russia are presented in this review article. Plan of measures for
reduction of mortality from ischemic heart disease (IHD) was created in 2015.
This plan... |
25,675 | [Own and Parental Predictors of Low Blood Level of High Density Lipoprotein
Cholesterol in Offspring of Persons With Early Coronary Heart Disease]. | AIM: to elucidate own and parental predictors of low levels of high density
lipoprotein cholesterol (HDL-C) in blood of children of persons with early
coronary heart disease (ECHD) (onset less or equal 55 years, men, or less or
equal 60 years, women).
METHODS: We examined 305 families: probands with ECAD (n=289, 69.... |
25,676 | [Effect of Combined Antihypertensive Therapy With Perindopril and Indapamide on
Morpho-Functional Parameters of The Heart, Blood Vessels of Small and Medium
Caliber in Patients With Essential Hypertension]. | AIM: to study effect of therapy with fixed combination of angiotensin-converting
enzyme infibitor and diuretic on structural-functional parameters of the heart
and vessels and cognitive function.
MATERIAL AND METHODS: We included into this study 30 patients (20 women) with
mean age 60.06+/-10.19 years, duration of h... |
25,677 | [Comparative Assessment of Effects of Free and Fixed Combinations of Hypotensive
Drugs on Quality of Life of Patients With Arterial Hypertension of High and Very
High Risk]. | PURPOSE: comparative assessment of effects of free and fixed combinations of
hypotensive drugs on quality of life (QL) of patients with arterial hypertension
(AH) of high and very high risk of cardiovascular complications.
MATERIAL: Study group comprised 120 patients (70% men, 30% women, age 45-65
years) with degree... |
25,678 | [Masked Arterial Hypertension in Employed Adult Women: Aspects of Screening and
Prognostication]. | Masked (M) hypertension (H) remains an unsolved problem of cardiology. Gender
aspects of MH require further pathogenetic deciphering and clinical
interpretation. We used breathe-hold test and 24-hour blood pressure (BP)
monitoring for detection of MH in 275 female middle- aged employees. MH
Prevalence of MH was 7.7... |
25,679 | [Evaluation of Direct and Indirect Expenditures for Management of Patients With
Stable Ischemic Heart Disease After Stenting of Coronary Arteries]. | Assessment of cost of management of patients during 1 year after stenting of
coronary arteries has shown that priority should be given to active introduction
into practical health care of technologies increasing duration of life and
lowering probability of invalidization. We stress the need for evaluation of
indire... |
25,680 | [The Study of Evidence Base for the Use of Lappaconitine Hydrobromide in
Patients With Atrial Fibrillation]. | Lappaconitine Hydrobromide (LH, allapinin) has been included by authors of
National Guidelines on Diagnosis and Treatment of Atrial Fibrillation (AF), 2012
in the number of medications recommended for use in patients with AF for rhythm
control. Moreover, LH is also included into the List of Vital and Essential
Medi... |
25,681 | [Assessment of Efficacy and Safety of Metabolic Therapy With Trimetazidine MB in
Patients With Ischemic Heart Disease and Chronic Heart Failure]. | Study purpose - to assess clinical and hemodynamic parameters in patients with
ischemic heart disease (IHD) with and without use of metabolic therapy with
trimetazidine MB.
MATERIALS: Seventy four patients with IHD, 40 of whom in addition to the main
therapy for 3 months received metabolic preparation trimetazidine ... |
25,682 | [On Synergism of Potassium and Magnesium in Maintenance of Myocardial Function]. | AIM: systematization of studies of synergistic effect of potassium and magnesium
on myocardial function.
MATERIAL AND METHODS: Analysis of an array of literature using methods of
computer learning.
RESULTS: Synergism of potassium and magnesium is driven by common causes of
deficit (low content in diet, abnormal rena... |
25,683 | [Problems of Diagnosis and Treatment of Pulmonary Hypertension in Old Patients
With Chronic Obstructive Pulmonary Disease]. | The article contains consideration of risk factors of pulmonary hypertension
(PH), clinical states associated with PH, and effect of age on susceptibility to
PH in patients with chronic obstructive pulmonary disease (COPD). We have
analyzed the prevalence of PH associated with COPD, its importance in the
structure ... |
25,684 | [Predictors of Cardiorespiratory Complications in Patients With Ischemic Heart
Disease After Coronary Artery Bypass Grafting]. | PURPOSE: to elucidate predictors of cardiorespiratory complications during the
early postoperative period after coronary artery bypass grafting (CABG) in
patients with ischemic heart disease (IHD).
MATERIAL AND METHODS: We examined 180 patients with IHD (mean age
59.3+/-1.23years). Prior to surgery we assessed their... |
25,685 | [The Problem of Minimally Changed Coronary Arteries at Elective Coronary
Angiography]. | AIM: to study rates and possible causes of detecting "clean" coronary arteries
at elective coronary angiography.
MATERIAL AND METHODS: Medical records of 711 patients who had undergone elective
coronary angiography (ECAG) between 01/04 and 31/05 2014 were retrospectively
reviewed. Four groups were distinguished: gro... |
25,686 | [The First Experience of Using Very Long Stents Covered With Sirolimus (4060 mm)
in the Treatment of Patients With Extensive and Diffuse Lesions of the Coronary
Arteries]. | OBJECTIVES: To assess the clinical outcome of one year follow-up in patients
with diffuse long lesions treated with extra-long sirolimus-eluting stents.
METHODS AND RESULTS: 85 patients underwent implantation of very long BioMime
stents during the period from March 2014 to February 2016.
RESULTS: The angiographic suc... |
25,687 | [Outcomes of Various Revascularisation Strategies in the Elderly STEMI Patients
With Multi-Vessel Coronary Pathology]. | AIM: to assess safety and efficacy of single stage complete revascularization by
multivessel stenting as primary percutaneous coronary intervention (pPCI) in
elderly and middle aged patients with acute ST-elevation myocardial infarction
(STEMI).
MATERIAL AND METHODS: We included in this analysis data on 327 of 1690 ... |
25,688 | [Adherence of Patients to Antihypertensive Therapy With Combination of
Perindopril and Indapamide According to Data of the FORSAGE Program]. | AIM: to assess adherence of patients to antihypertensive therapy with fixed
perindopril and indapamide combination (FPIC) as well as to elucidate causes of
changes of therapy after 6 months.
MATERIAL AND METHODS: In 6 months after termination of the FORSAGE observational
program we interviewed over telephone 148 of ... |
25,689 | [Atrial Fibrillation After Coronary Artery Bypass Grafting]. | PURPOSE: to identify the role of factors of inflammation and myocardial ischemia
in the development of atrial fibrillation (AF) in the early postoperative period
after coronary artery bypass grafting (CABG).
METHODS: We enrolled in this study 96 patients with ischemic heart disease who
had undergone CABG. Patients w... |
25,690 | [Subpopulation Composition of CD4+ T-lymphocytes as Factor Contributing to the
Progression of Atherosclerosis of Carotid Arteries]. | AIM: to assess prognostic significance of blood content of regulatory and
effector T-lymphocytes for progression of atherosclerosis (AS) of carotid
arteries.
MATERIAL AND METHODS: We enrolled in this study 33 men with various severity of
carotid AS. Carotid artery duplex scan was done at admission and in 1 year afte... |
25,691 | [Blood Levels of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Men
from Different Population Groups and Its Relation to Unfavorable Long-Term
Prognosis]. | AIM: of the study was to investigate blood levels of proprotein convertase
subtilisin/kexin type 9 (PCSK9) in men from different population subgroups,
their associations with cardiovascular risk factors and with unfavorable 7-years
long-term prognosis.
MATERIAL AND METHODS: The study included three subgroups of men ... |
25,692 | [Fixed-Drug Combination Amlodipine, Indapamide and Perindopril: New Horizons of
Antihypertensive Therapy]. | High prevalence of arterial hypertension and low rate of blood pressure (BP)
control in patients with arterial hypertension require more intensive approaches
to antihypertensive therapy. Every patient with arterial hypertension is
characterized by different predominant pathophysiologic mechanisms in different
perio... |
25,693 | [The Experience of Use Triple Antithrombotic Therapy in Patients With Acute
Coronary Syndrome and Atrial Fibrillation]. | AIM: In real life to evaluate the effectiveness and safety of apixaban with
double antiplatelet therapy for prevention of stroke and systemic embolism in
patients with non-valvular atrial fibrillation and the recent episode of acute
coronary syndrome without ST segment elevation.
MATERIALS AND METHODS: 8 patients wi... |
25,694 | [Prevention of Cardiovascular Events: Are All Recommendations Applicable to
Elderly Patients With Senile Asthenia?]. | Primary prevention of cardiovascular events is based on achievement of optimal
control of risk factors - arterial hypertension, dyslipidemia, glycemia - in
accordance with current recommendations of scientific societies. But most
rapidly growing segment of population - elderly and old individuals - have been
underr... |
25,695 | [Adaptation to Intermittent Hypoxia-Hyperoxia in the Rehabilitation of Patients
With Ischemic Heart Disease: Exercise Tolerance and Quality of Life]. | AIM: to assess effect of interval hypoxic-hyperoxic training (IT) on exercise
tolerance and quality of life of patients with ischemic heart disease (IHD)
receiving optimal medical therapy, as well as the safety of IHHT use.
METHODS: Patients with stable IHD with functional class II and III angina (n=46)
were randomi... |
25,696 | [Association of Serum Levels and Gene Polymorphism of Vascular Endothelium
Growth Factor With Ischemic Heart Disease in Type 2 Diabetic Patients]. | AIM: to study serum levels of vascular endothelium growth factor family peptides
(VEGF-A, VEGF-C and VEGF-D) and functional gene polymorphisms of VEGFA gene
(rs699947 and rs3025039) in patients with type 2 diabetes (T2D) depending on the
presence of ischemic heart disease (IHD).
MATERIALS AND METHODS: The study invo... |
25,697 | [Predictors of Electrical Myocardial Instability in Men With Arterial
Hypertension and Obstructive Sleep Apnea-Hypopnea Syndrome]. | OBJECTIVE: To access the detectability of corrected QT interval (QTc)
prolongation ( more or equal 450 ms) and increased QT dispersion (QTd more or
equal 60 ms) in men with obstructive sleep apnea-hypopnea syndrome (OSAS) and
newly diagnosed arterial hypertension (AH).
MATERIAL AND METHODS: We included in this study... |
25,698 | [Noninvasive Electrophysiological Mapping in Patients With Complete Left Bundle
Branch Block and Different Modes of Biventricular Pacing]. | OBJECTIVE: to investigate possibilities of noninvasive electrophysiological
mapping (NEM) during biventricular (BiV) pacing and to compare the results with
data of 12 lead ECG and tissue Doppler echocardiography (TDI).
MATERIAL AND METHODS: The study included 25 patients with complete left bundle
branch block (LBBB)... |
25,699 | [Effectiveness of Extended Myectomy in Patients With Hypertrophic Cardiomyopathy
With Midventricular Obstruction]. | PURPOSE: to assess effectiveness and safety of extended myectomy performed in
patients with hypertrophic obstructive cardiomyopathy (HOCM) with midventricular
obstruction.
MATERIAL AND METHODS: Between 2010 and 2013 185 HOCM patients were operated for
left ventricular outflow tract (LVOT) obstruction. Among these pa... |
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