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27,800 | [Atherosclerosis of abdominal aorta and carotid arteries and its correlation
with blood serum lipid levels in cholelithiasis]. | AIM: To elucidate relationship between cholelithiasis and presence and severity
of atherosclerosis in abdominal aorta and carotid arteries.
MATERIAL AND METHODS: Ultrasound investigation of vessels and abdominal organs,
determination of blood serum total, high density lipoprotein cholesterol and
triglycerides were c... |
27,801 | [Longitudinal global and regional left ventricular function in patients with
hypertensive disease (tissue Doppler echocardiography data)]. | Impulse tissue doppler study was carried out in 154 patients with hypertensive
disease (age 35-60 years) and 39 practically healthy volunteers (mean age
43.4+/-5.5 years). According to left ventricular geometry the following groups
of patients were distinguished (after A.Ganau): with normal geometry (n=47),
with co... |
27,802 | [Evaluation of cerebral hemodynamics in patients with syndrome of obstructive
sleep apnea by long term registration of rheoencephalogram]. | AIM: To assess cerebral hemodynamics during sleep in patients with syndrome of
obstructive sleep apnea.
METHODS: Long term monitoring of rheoencephalogram. Data processing consisted in
construction of trends (curves of changes of rheographical parameters during any
selected time interval).
RESULTS AND CONCLUSION: Cy... |
27,803 | [Tissue plasminogen activator and plasminogen activator inhibitor gene
polymorphisms: possible relation to atherosclerosis and its complications]. | In the present review the dates about association of genetic variants of a
plasminogen activator inhibitor type 1 (PAI-1) and tissue plasminogen activator
(tPA) with ischemic heart disease and atherosclerosis of other localization are
toted. The singularities of synthesis of PAI-1 and tPA, possible paths of
regulat... |
27,804 | [Dynamics of heart rate variability in ischemic heart disease patients after
coronary artery bypass grafting]. | AIM: To study dynamics of 24-hour heart rate variability (HRV) after coronary
artery bypass grafting (CABG) and to elucidate relationship between HRV dynamics
and clinical course of the disease.
METHODS AND MATERIAL: A novel methodological approach to evaluation of HRV based
on measurement of mean weighted rhythmogr... |
27,805 | [The use of fatty acid beta-oxidation inhibitor mildronate as monotherapy or in
combination with atenolol in patients with left ventricular dysfunction after
myocardial infarction]. | AIM: To assess antiischemic efficacy, safety and effect on myocardial perfusion
of a course treatment with mildronate (as monotherapy and in combination with
atenolol) in patients with postinfarction left ventricular dysfunction
associated with moderate heart failure.
MATERIAL AND METHODS: Patients (n=47) with posti... |
27,806 | [Left ventricular remodeling in chronic heart failure: clinical-morphological
parallels]. | AIM: To study morphofunctional state of left ventricular and right atrial
myocardium in chronic heart failure at tissue, cellular and subcellular levels
and to assess relationship between observed morphological changes and
echocardiographical characteristics of left ventricular remodeling.
RESULTS AND CONCLUSION: My... |
27,807 | [Register of acute coronary syndromes in Russia: treatment and in hospital
outcomes in non-ST elevation acute coronary syndrome]. | Data from about 50 consecutive patients with acute coronary syndromes aged > or
=18 years admitted to 59 hospitals in different Russian cities were collected
between November 2000 and July 2001. In addition to presumably ischemic symptoms
within previous 24 hours they were to have ischemic ECG changes, documented
c... |
27,808 | [The effect of risk factors on development of myocardial infarction among
professional drivers in Kaunas]. | We investigated effect of risk factors on elevated first myocardial infarction
risk among professional drivers. We carried out case-control study among men
aged 25-64 years in Kaunas in 1997-2000. We identified myocardial infarction
cases (n=448) from the myocardial infarction hospital register (International
Class... |
27,809 | [Pathomorphological features of atherosclerotic plaques in acute coronary
syndrome]. | We studied transverse cross-sections (5 mm apart) of coronary arteries of 45 men
and women who died of acute myocardial infarction at the age of 41-79 years.
Both stable and unstable atherosclerotic plaques were found in all cases. Stable
plaques consisted of solid fibrous tissue with small amount of lipids and
cel... |
27,810 | [Effect of radio frequency catheter ablation on spectral parameters of heart
rate variability in patients with paroxysmal supraventricular tachyarrhythmias]. | AIM: To assess effect of radio frequency catheter ablation (RFCA) on heart rate
variability (HRV) in patients with supraventricular tachyarrhythmias (SVT).
METHODS: Spectral analysis of HRV on 5-minute ECG strips was carried out in 19
patients with SVT before and 2 days after RFCA.
RESULTS: Both total and high freque... |
27,811 | [Effects of Na(+)/H(+)-exchanger inhibition on metabolism of area at risk and
myocardial infarct size in dogs]. | The aim of this work was to study cardioprotective effects of BIIB 722, a novel
Na(+)/H(+) exchanger-1 inhibitor, during regional ischemia and reperfusion in
canine myocardium. The experiments were carried out on anaesthetized dogs
intubated and artificially ventilated with room air enriched with oxygen.
Regional i... |
27,812 | [Genetic predictors of left ventricular hypertrophy: do polymorphisms of
peroxisome proliferator activated nuclear receptor genes play any role?]. | AIM: To assess possible associations of polymorphic markers of PPARA and PPARG2
genes with presence of left ventricular hypertrophy (LVH) in patients with
hypertension.
MATERIAL: Patients with hypertension (n=163, mean age 60.93+/-0.82 years) with
(n=110) and without (n=53) LVH.
METHODS: Echocardiography was used fo... |
27,813 | [Role of Chlamydia, mycoplasma and cytomegalovirus infection in the development
of coronary artery disease]. | AIM: To assess relationship between some infection factors and presence of
coronary heart disease.
MATERIAL: Patients with myocardial infarction (n=56), unstable angina (n=50),
stable angina (n=50) and age - matched controls (n=49).
METHODS: Levels of IgG, IgM, IgA antibodies to Chlamydia pneumonia, Chlamydia
tracho... |
27,814 | [Stress echocardiography with the use of impulse wave tissue Doppler technology
in diagnosis and quantitative evaluation of concealed myocardial ischemia]. | AIM: To elucidate the role of the use of impulse-wave tissue doppler technology
during stress echocardiography with transesophageal atrial pacing for diagnosis
and evaluation of concealed myocardial ischemia.
MATERIAL: Patients (n=82, 72 men, 10 women, mean age 43+/-10 years) with
syndrome of cardiac pain of obscure... |
27,815 | [Results of pharmacoepidemiological study of arterial hypertension in Russia
(PIFAGOR)]. | AIM: To assess physicians preferences concerning the use of various groups of
antihypertensive drugs in Russia.
METHODS: Special questionnaires containing 8 questions related to preferential
adherence to representatives of various groups of antihypertensive drugs were
distributed among practicing physicians who rout... |
27,816 | [Hyperplasia and degranulation of mast cells in intima of the aorta and
pulmonary artery in acute myocardial infarction]. | AIM: To study morphological and functional state of mast cells from intima of
the aorta and pulmonary artery associated with acute cardiovascular failure due
to myocardial infarction.
MATERIAL: Vessels of 44 men who died of acute myocardial infarction at the age
of 42-73 years.
METHODS: Intimal cellular elements wer... |
27,817 | [Salt consumption and arterial hypertension]. | Solution of the problem of hypertension lies in prevention. And here it is
impossible to get along without risk factor concept. Most valuable risk factor
for development of hypertension is salt - sodium ion at first hand. Increased
salt intake with diet modifies effect of such important risk factors of
hypertension... |
27,818 | [Peroxisome proliferator activated nuclear receptors: possible role in the
development of atherosclerosis]. | Peroxisome proliferator activated nuclear receptors (PPAR) belong to steroid
receptors and are represented by 3 types: PPAR alpha, PPAR beta, PPAR gamma.
PPAR alpha is a key regulator of fatty acid beta-oxidation, participates in
development of inflammatory reaction and atherosclerosis formation. Main effects
of fi... |
27,819 | [Diastolic function of the heart in patients with chronic heart failure and
methods of diagnosis of its impairment by tissue Doppler echocardiography]. | Negative role of diastolic dysfunction in the heart failure formation is out of
doubt now. But the problem of complex diagnostics of this dysfunction is still
open. New scientific and technical developments widen our understanding of
diastolic function of the heart and possibilities of its assessment in patients
wi... |
27,820 | [New guidelines of the Joint National Committee (USA) on Prevention, Diagnosis
and Management of Hypertension. From JNC VI to JNC VII]. | Need for update of guidelines of the Joint National Committee (USA) on
Prevention, Diagnosis and Management of Hypertension was based on necessity to
adopt changes based on results of recent studies as well as creation of more
simple and convenient variant for practical physicians. Compared with JNC VI
most importa... |
27,821 | [Left ventricular hypertrophy in hypertension. Part II. Prognostic value of left
ventricular hypertrophy]. | This part of review is based on results of prospective studies of prognostic
value of left ventricular hypertrophy defined by electro- or echocardiographical
criteria. Increased risk of cardiovascular complications has been found to be
associated with left ventricular hypertrophy detected not only by voltage ECG
cr... |
27,822 | [Metoprolol in the treatment of essential hypertension]. | In the review the basic studies devoted to researching of effectiveness of
metoprolol in treatment of essential hypertension and also influence of this
drug in the prognosis in this group of patients, are summarized. The
specification on pharmacokinetic properties of the drug is shown. Outcomes of
two studies (BCAP... |
27,823 | [Characteristics of coronary artery lesions in patients with painless myocardial
ischemia]. | AIM: To assess extent and localization of coronary artery lesions in patients
with painless myocardial ischemia.
MATERIAL AND METHODS: Tredmill stress-echocardiograghy, Holter ECG monitoring
and coronary angiography were carried out in 59 male patients (age 30-72, mean
54.5 years) with either angina pectoris or pain... |
27,824 | [Automatic analysis of cardiological signals for diagnosis of ischemic heart
disease]. | A new noninvasive method for early detection of ischemic heart disease based on
singular value decomposition is introduced. The method automatically explores
waveforms of an ECG by making projections of individual ECG leads onto axes
formed by the first three components of the singular value decomposition
performed... |
27,825 | [Nebivolol in the treatment of ischemic heart disease patients with chronic
heart failure]. | AIM: To assess effectiveness of inclusion of nebivolol in complex therapy of
patients with chronic heart failure (CHF) due to ischemic heart disease (IHD).
MATERIAL: Patients (n=62, age 47-73 years) with NYHA class II-III CHF and left
ventricular (LV) ejection fraction (EF) less than 45% receiving standard therapy
+... |
27,826 | [Blood pressure dynamics and prognostication of hypertension: 20-year follow-up
of children's cohort]. | AIM: To track dynamics of blood pressure (BP) from childhood to young maturity
and to determine predictors of hypertension.
METHODS: School children (n=1082) were examined in a framework of an
international program on juvenile hypertension in 1976-1977. Samples of this
initial cohort were reexamined in 1988 (n=444) ... |
27,827 | [Efficacy of nondrug correction of hypertension in general medical practice]. | Effectiveness of nondrug correction of elevated blood pressure was assessed in a
group of hypertensives selected from participants of a study of prevalence of
cardiovascular risk factors conducted in one of Saint Petersburg districts.
Patients were divided into 3 subgroups in which the following interventions were
... |
27,828 | [Lowering of antiatherogenic significance of high density lipoproteins in obese
persons]. | Protein and lipid components of blood serum high density lipoproteins (HDL)
responsible for their functional activity were studied before and after fat load
in subjects with normal body mass and various types of obesity. Subjects with
abdominal obesity compared with those with gluteo-femoral obesity and normal
body... |
27,829 | [QT interval shortening in families with history of sudden death at young age]. | AIM: To assess frequency of short QT interval among members of families with
history of young age sudden death.
MATERIAL: Eleven children aged 3-16 years (mean age 11.2+/-4.2 years) from
families with cases of sudden death at young age (<40 years) not caused by an
obvious disease according to autopsy data. None of t... |
27,830 | [Left ventricular geometry in inhabitants of Tallinn (an echocardiographic
population study)]. | Echocardiography was performed in 325 men and 398 women in the framework of a
population survey of inhabitants of Tallinn aged 35 to 59 years in 1999-2001.
Left ventricular geometry was analyzed according to generally recognized four
types. Prevalence of concentric hypertrophy was similar in men and women (7.7%
and... |
27,831 | [Antioxidants in complex therapy of atherosclerosis: pro et contra]. | The review contains current insights into the role of free radical processes in
formation of oxidative stress in atherosclerosis and its relevance to therapy
and prevention. Data of epidemiological studies evidence for existence of
correlations between blood plasma content of antioxidant vitamins and presence
of si... |
27,832 | [Systolic and diastolic left ventricular dysfunction--independent types of
cardiac failure or two sides of a single process?]. | At present disturbances of systolic and diastolic myocardial function are
subjected to intensive study. Most researches acknowledge possibility of
development of diastolic dysfunction in the absence of systolic dysfunction.
Meanwhile disturbances of systolic and diastolic myocardial functions have
common pathogenet... |
27,833 | [Myocardial infarction in patients with infectious endocarditis]. | Myocardial infarction (MI) developed in 9% of 230 patients with active
infectious endocarditis. Development of MI was associated with worsened clinical
course and poorer prognosis of infectious endocarditis. MI manifested with pain
in 43 and was painless in 57% of these cases. In 29% of patients initial
manifestati... |
27,834 | [Comparison of eprosartan and captopril in left ventricular systolic
dysfunction: relation of efficacy to myocardial viability]. | Patients with left ventricular ejection fraction below 45% (mean 39+/-3.7%) were
randomized either to captopril (n=33) or eprosartan after miocardial infarction
(n=33) on days 3-7 of myocardial infarction. All patients were subjected to
echocardiography and 40 to perfusion myocardial scintigraphy with
(99m)TC-Techn... |
27,835 | [Novel functional stress test (stochastic) and perspectives of its application]. | AIM: To assess advantages of a stochastic functional stress test during which
workloads change according to law of random numbers.
METHOD: Results of stochastic tests and standard stress tests with stepwise
increments of workloads were compared in 45 healthy subjects and 90 patients
with ischemic heart disease (45 w... |
27,836 | [Clinical and functional characteristics of hypertension in patients consuming
excessive amounts of salt]. | Salt sensitivity threshold was measured in 230 patients with arterial
hypertension and clinical and functional characteristics of hypertension in
patients consuming excessive amounts of salt were studied. Patients with high
salt sensitivity threshold consumed more salt with food and represented a
special group of p... |
27,837 | [Correction of rate and structure of ventricular rhythm in permanent atrial
fibrillation: a novel pathogenetic approach]. | AIM: To analyze action of digoxin and some non-digitalis drugs (beta-blockers,
verapamil, amiodarone, d,l-sotalol) and their combinations on electrical
activity of atria, frequency and structure of ventricular rhythm in patients
with permanent atrial fibrillation.
MATERIAL AND METHODS: One hundred patients with perm... |
27,838 | [Endothelial dysfunction and risk factors of its development in subjects with
family history of atherosclerosis]. | Brachial artery blood flow reactions to hyperemia and hyperventilation
(endothelium dependent vasodilation and vasoconstriction) were studied by
doppler sonography in 60 persons aged 19-39 years with family history of
atherosclerosis and risk factors of this disease. Reactivity of peripheral
artery and risk factors... |
27,839 | [Protective effect of hydrophilic ubiquinone on cardiac muscle during oxidative
stress]. | AIM: To assess effects of long term administration of a natural antioxidant
ubiquinone on isoproterenol induced myocardial injury.
METHODS: Rats were given hydrophilic ubiquinone with water for 8 weeks.
RESULTS: Long term use of ubiquinone did not affect myocardial ultrastructure
and relative myocardial weight. The d... |
27,840 | [Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of
pharmacology and experience of use in arterial hypertension]. | Candesartan is a novel high-affinity type 1 AT(1)-receptor blocker characterized
by prolonged binding to and slow dissociation from the receptor. Pharmacokinetic
properties of candesartan explain its pronounced and lengthy (24-36 hours)
antihypertensive action which does not depend on patients sex, age and body
mas... |
27,841 | [Clinical value of some factors of gene transcription in heart diseases]. | Two families of gene transcription factors - these review deals with peroxisome
proliferator activated receptors (PP AR) and nuclear factor kappa B (NFkappaB).
PPAR family controls lipid metabolism, processes of inflammation and
atherothrombosis. Activation of NFkappaB initiates transcription of genes of
such proin... |
27,842 | [Register of Acute Coronary Syndromes in Russia: Management and Inhospital
Outcomes in ST Elevation Acute Coronary Syndrome]. | Data of about 50 consecutive patients with acute coronary syndromes aged at
least 18 years admitted to 59 hospitals in different Russian cities were
collected from November 2000 to July 2001. In 1412 patients included into
registry presumably ischemic symptoms within previous 24 hours were associated
with ST-segmen... |
27,843 | [Results of nonmedical interventions in multicenter randomized open study of
efficacy of lifestyle modification and therapy with quinapril in patients with
obesity and hypertension]. | There is a pathogenetic interrelationship between obesity and hypertension.
Moreover it has become evident that the use of most modern and active
antihypertensive drugs can not be effective without concomitant treatment of
obesity. This study was conducted in 18 cities of Russian Federation in order to
demonstrate ... |
27,844 | [Rheological properties of blood and endothelial function in patients with
hypertensive disease]. | Patients with hypertension are characterized by elevated platelet and
erythrocytes aggregation and presence of relationship between rigidity of red
blood cells and myocardial mass index. They also have increased number of
leukocytes in peripheral blood, enhanced adhesive ability of neutrophils,
increased representa... |
27,845 | [Complex assessment of vasomotor function of vascular endothelium in patients
with hypertension]. | Vasomotor function of vascular endothelium was studied in 62 patients with grade
1-2 hypertension with moderate and high added risk. Methods included study of
brachial and middle cerebral artery endothelium dependent and independent
vasodilation/vasoconstriction, measurement of plasma levels of nitric oxide
metabol... |
27,846 | [The state of microcirculation during use of long acting metoprolol]. | The aim of the study was to assess the effect of prolonged action metoprolol on
the microcirculation in patients with essential hypertension (EH). We studied 51
patients with EH aged 53,4+/-4,5 years. After 7-10 days of "wash-out" period and
after 8 weeks of prolonged action metoprolol (betaloc ZOK) the state of
mi... |
27,847 | [Clinical, angiographical, and procedural causes of acute vessel closure during
transluminal coronary intervention]. | AIM: To elucidate factors related to acute vessel closure (AVC) after
transluminal coronary intervention.
METHODS: From population of 10439 patients subjected to transluminal coronary
intervention 2 groups were formed: with (n=885) and without (n=885) acute vessel
closure (AVC). Twenty five clinical, angiographical ... |
27,848 | [Effect of trimetazidine on regressione of ischemic dysfunction of myocardium
after coronary bypass surgery on beating heart]. | AIM: To study effect of trimetazidine on restoration of hibernating myocardium
after myocardial revascularization on beating heart.
MATERIAL: Patients with ischemic heart disease subjected to direct myocardial
revascularization on beating heart: 25 patients received trimetazidine (60
mg/day) in pre and postoperative... |
27,849 | [Hemorheological changes during mammary coronary bypass grafting]. | Hemorheological studies were performed in 44 patients subjected to mammary
coronary bypass surgery during induction of anesthesia, at initiation of
cardiopulmonary bypass, at the end of operation, on the 1(st) and 2(nd) or 3(rd)
postoperative day. Methods included determination of whole blood and plasma
viscosity w... |
27,850 | [Assessment of phenomenology of attacks of atrial fibrillation before and after
treatment with clonasepam]. | AIM: To assess phenomenology of attacks of atrial fibrillation using
psychovegetative index (PVI) and to compare PVI values obtained before and after
treatment with clonasepam in patients with paroxysmal atrial fibrillation.
MATERIAL: Patients with nonrheumatic atrial fibrillation (n=105).
METHODS: PVI was calculated... |
27,851 | [Aspartic Acid and mannitol enhance protective efficiency of asanquineous
cardioplegic solution]. | The aim of this work was to assess effects of a novel asanquineous cardioplegic
solution (CP-5), buffered with trisamine (pH 7.6+/-0.1 at 22 degrees C) and
containing 21.5 mM aspartic acid and 20.0 mM mannitol, on postischemic
functional and metabolic recovery of isolated rat heart. A modified Ringer
solution with ... |
27,852 | [Left Ventricular Hypertrophy in Hypertension. Part III. Reversibility of Left
Ventricular Hypertrophy During Treatment With Antihypertensive Drugs]. | Results of prospective trials of effects of various antihypertensive drugs on
left ventricular hypertrophy in patients with hypertensive disease are reviewed.
According to 2 meta-analyses angiotensin converting enzyme inhibitors are most
effective inducers of regression of left ventricular hypertrophy. However in
c... |
27,853 | [Arterial hypertension in a framework of metabolic syndrome: special features
and principles of drug correction]. | About 60% of patients with mild and moderate hypertension have insulin
resistance and half of them have clinically manifest metabolic syndrome which
comprises abdominal obesity, hyperlipidemia, impaired glucose tolerance,
hypertension and insulin resistance. In a framework of metabolic syndrome
hypertension is char... |
27,854 | [Effect of high doses of broncholytics on the state of cardiovascular system
during treatment of sever exacerbation of bronchial asthma]. | The use of broncholytic drugs through nebulizer is a standard treatment for
acute episodes of bronchial asthma. However doses of these drugs administered by
nebulizer can be much higher than those applied when metered dose inhaler is
used. These doses have a potential of cardiotoxic effects.
MATERIAL: Patients (n=75... |
27,855 | [Apoptosis and hibernation of cardiomyocytes of periscar zone as factor of
chronic cardiac aneurysm progression]. | Tissue specimen from chronic aneurysms and adjacent myocardium obtained at
aneurysmectomy and coronary bypass surgery from 46 patients were subjected to
morphological study. Immunohistochemical methods and electronic microscopy were
applied for detection of apoptosis and hibernation of cardiomyocytes in 11 cases
an... |
27,856 | [Clinical value of morphological analysis of radial and internal mammary
arteries in patients with ischemic heart disease]. | Morphological study of intraoperative biopsies of radial and internal mammary
arteries taken from patients with ischemic heart disease during coronary bypass
surgery revealed structural alterations of intima and media mostly in radial
artery. These alterations depended on severity of arterial hypertension,
presence... |
27,857 | [Prognosis of unstable angina resulting from restenosis after percutaneous
angioplasty of saphenous vein grafts]. | AIM: To assess frequency of unstable angina due to restenosis after percutaneous
angioplasty of venous grafts and to elucidate risk factors of its development.
MATERIAL AND METHODS: Percutaneous interventions were successfully performed in
100 out of 106 patients with venous graft stenoses. These patients were follow... |
27,858 | [Effect of long-term physical training on hemostasis in patients with coronary
heart disease and non-insulin dependent diabetes]. | AIM: To study effects of 6-month physical training on some parameters of
hemostasis in patients with coronary heart disease and non-insulin dependent
diabetes (NIDDM).
RESULTS: Long-term physical training resulted in lowering of fibrinogen level
and increase of fibrinolytic activity assessed as euglobulin fraction c... |
27,859 | [The treatment of coronary atherosclerosis: effect of the use of stents on
immediate and long term results of coronary angioplasty]. | Immediate and long term results of 2 methods of coronary angioplasty (balloon
dilatation and stenting) were analyzed retrospectively. During 10 years
proportion of stent implantations increased 30-fold reaching 95-97% of coronary
interventions. This was associated with improvement of immediate results of
angioplast... |
27,860 | [Clinical assessment of immediate results of various methods of myocardial
revascularization in ischemic heart disease patients with isolated anterior
descending coronary artery disease]. | Open heart coronary artery bypass grafting (CABG), minimally invasive coronary
artery surgery, transluminal balloon coronary angioplasty (TBCA) and coronary
stenting were carried out in 25, 35, 12 and 38 patients with isolated anterior
descending coronary artery disease, respectively. In immediate period after
proc... |
27,861 | [Relation between resistance to oxidation and cholesterol acceptance of high
density lipoproteins in patients with ischemic heart disease]. | Cholesterol (CH) acceptance ability of high density lipoproteins (HDL) was
assessed in 43 ischemic heart disease (IHD) patients, including patients with
post-infarction cardiosclerosis and class II-III effort angina. CH acceptance
ability of HDL was measured as increment of HDL CH after incubation with
artificial C... |
27,862 | [Comparative assessment of efficacy of tissue plasminogen activator and
streptokinase in the treatment of patients with acute myocardial infarction]. | AIM: To compare results of treatment of patients with acute myocardial
infarction with tissue plasminogen activator (TPA) and streptokinase.
MATERIAL AND METHODS: TPA (100 mg intravenously) and streptokinase (1500000 U
intravenously) were used for thrombolytic therapy of acute myocardial infarction
in 114 and 118 pa... |
27,863 | [Clinical Efficacy of Combination Therapy With Trimetazidine and Angiotensin
Converting Enzyme Inhibitors in Patients With Hypertension and Ischemic Heart
Disease Associated With Type II Diabetes]. | AIM: To assess in a randomized open study effect of 12-15 week use of
angiotensin converting enzyme inhibitors (ACEI) with and without trimetazidine
on myocardial perfusion reserve in patients with ischemic heart disease (IHD)
and/or hypertension associated with type II diabetes.
MATERIAL: Patients (n=69) receiving ... |
27,864 | [Effect of fixed low dose combination of perindopril and indapamide on processes
of cardiovascular remodeling in previously untreated patients with
hypertension]. | AIM: To assess changes of blood pressure (BP) and processes of cardiovascular
remodeling during treatment of previously untreated patients with hypertension
with fixed low dose combination of perindopril and indapamide.
MATERIAL: Patients with untreated hypertension (n=30, mean age 46.7+/-1.8 years,
16 men, 14 women... |
27,865 | [Comparison of QT-Interval Measurement Techniques and Their Clinical Value]. | Long QT-interval is one of most important predictors of risk of development of
life threatening arrhythmias and sudden death. Correct measurement of
QT-interval is essential for diagnosis of its prolongation. At present the
Bazett formula for calculation of corrected QT (QT(c) = QT/ radical (RR)) is a
standard meth... |
27,866 | [Pathogenesis, clinical picture, and diagnosis of myopericarditides]. | Basing on own data and literature survey the authors analyze clinical course of
viral myopericarditides. Special emphasis is made on evolution of
electrocardiographical signs in which four stages are distinguished. It is noted
that incidence of hemorrhagic myopericarditides probably of viral nature is
increasing. T... |
27,867 | [Stroke and Other Thromboembolic Complications of Atrial Fibrillation. Part II.
Prevention With Warfarin]. | In part II of a series of papers on epidemiology and drug prevention of stroke
and other thromboembolic complications of atrial fibrillation the authors
present data on clinical pharmacology of oral anticoagulants as well as
discussion of results of randomized studies demonstrating high efficacy of
warfarin in prim... |
27,868 | [First experience with "live" three-dimensional echocardiography in Russia]. | Revival of interest to three-dimensional echocardiography during recent years
was invoked by introduction of essentially novel ultrasound technology of "live"
three-dimensional imaging. We introduce here the first experience of the use of
<<live>> three-dimensional echocardiography in Russia comprising examination o... |
27,869 | [Enoxaparin for the Treatment of Unstable Angina and Non-ST Segment Elevation
Myocardial Infarction: the ENO-INT Study]. | AIM. To assess safety and efficacy of enoxaparin in patients with UA/NSTEMI in
an open-label, multi-centre, non-comparative study and to compare the results
with data from large-scale randomized trials ESSENCE and TIMI-11B.
METHODS: Patients hospitalized with a diagnosis of recent UA/NSTEMI were treated
with 1 mg/kg... |
27,870 | [The use of intraaortic balloon counterpulsation in patients with acute
myocardial infarction]. | Intraaortic balloon counterpulsation was implemented in 11 patients with acute
myocardial infarction and 1 patient with unstable angina. All patients had
severe multivessel coronary artery disease. In 9 patients counterpulsation was
used in conjunction with percutaneous transluminal coronary angioplasty, in 3 -
wit... |
27,871 | [Long-term therapy with anticoagulants in patients with nonvalvular atrial
fibrillation (prospective follow-up). Part I. Effect of 12-month therapy with
acenocoumarol on content of d-dimer, frequency of thrombosis and parameters of
hemodynamics of left auricle]. | AIM: To assess frequency of left auricular thrombosis and effect of long-term
therapy with acenocoumarol on auricular hemodynamics and system of hemostasis
and to elucidate predictors of effective therapy with acenocoumarol in patients
with nonvalvular atrial fibrillation.
MATERIAL: Patients (n=100) with nonvalvular... |
27,872 | [Comparative analysis of phenomenology of paroxysms of atrial fibrillation and
panic attacks]. | AIM: To study phenomenology of attacks of atrial fibrillation (AF) and to
compare it with phenomenology of panic attacks for elucidation of pathogenesis
of atrial fibrillation and for elaboration of rational therapeutic intervention
including those aimed at correction of psychovegetative abnormalities.
MATERIAL: Pat... |
27,873 | [On the role of insufficient mitochondrial energy production in primary
hypertension: the neurogenic constitutive of the pathogenesis]. | There are accumulated evidences on existence of an imbalance between energy
production and consumption in tissues in primary hypertension resulting in
insufficient compensation of energy and its deficiency in cells (human essential
hypertension, spontaneous hypertension in rats, SHR). An origin of these
abnormaliti... |
27,874 | [Psychoemotional stress tests and prospects for their use in cardiology]. | Social and economic transformations of the society enable to suggest an ever
increasing role of psychoemotional factors in the development of cardiovascular
pathology. The paper contains a review of psychoemotional functional stress
tests (arithmetic, speech, information, computer games). Stroop-testing method,
whi... |
27,875 | [Detection and morphofunctional predictors of left auricular thrombosis in
patients with atrial fibrillation]. | Atrial fibrillation significantly worsens quality and duration of patient's life
because of frequent development of thromboembolic complications. The main cause
of these complications is formation of intracardiac thrombosis. Prevalence of
left atrial thrombosis in patients with atrial fibrillation varies from 8 to
... |
27,876 | [Stroke and Other Thromboembolic Complications of Atrial Fibrillation. Part III.
Prevention With Aspirin]. | In part III of a series of papers on epidemiology and drug prevention of stroke
and other thromboembolic complications of atrial fibrillation the authors
present data on clinical pharmacology of aspirin as well as discussion of
results of randomized trials in which cerebroprotective efficacy and safety of
the use o... |
27,877 | [Quantitative myocardial perfusion assessment with magnetic resonance imaging in
patients with coronary artery disease]. | AIM: To elucidate feasibility of the absolute myocardial blood flow (MBF), total
coronary resistance (TCR), and myocardial blood flow reserve (MBFR)
quantification using MRI in patients with coronary artery disease (CAD).
MATERIAL AND METHODS: A total of 19 patients with angiographically documented
CAD and 9 healthy... |
27,878 | [Sigmental right ventricular contractile function in patients with ischemic
heart disease]. | Segmental right ventricular function was assessed by dobutamine stress
echocardiography in 101 patients with ischemic heart disease and multiple
coronary artery lesions. At rest local wall motion abnormalities were found in
69% of patients. Overall 505 segments of the right ventricle were analyzed (5
per patient). ... |
27,879 | [Anginal States provoked by psychogenic stimuli. To the problem of psychosomatic
reactions in patients with ischemic heart disease]. | Two types of vulnerability of coronary vessels damaged by atherosclerosis were
proposed basing on results of a study of 94 patients with psychosomatic
reactions accompanied with ischemia or myocardial infarction. First variant (35
patients) was characterized by stable course of the disease (high effort angina
witho... |
27,880 | [Relationship between heart rate changes during reflex tests and heart rate
variability in patients with recent myocardial infarction]. | BACKGROUND: Low heart rate variability (HRV) reflecting predominance of
sympathetic tone is an independent predictor of sudden cardiac death after
myocardial infarction (MI). We have previously shown that decreased heart rate
(HR) response during reflex tests (breathing 6 per minute and Valsalva maneuver
at the end... |
27,881 | [Efficacy of multifactorial preventive interventions in achievement of target
levels of low density lipoprotein cholesterol in survivors of myocardial
infarction]. | AIM: To assess Efficacy of multifactorial preventive Interventions in
achievement of target levels of low density lipoprotein cholesterol in survivors
of myocardial infarction.
METHODS: Design of the study was open randomized comparative prospective. Two
groups of patients with history of myocardial infarction were ... |
27,882 | [Allele Frequency Analysis of Four Single Nucleotide Polymorphisms Locating in
Promoter and 5'-Untranslated Regions of ABCAI Gene in Young Men - Survivors From
Myocardial Infarction]. | Analysis of allele distribution of four single nucleotide polymorphisms (C-17G,
C69T, G-191C and 319insG) of promoter and 5'-untranslated regions of the ABCA1
gene was carried out in a sample of 171 men, who had survived myocardial
infarction before 45 years, and in controls. Two-fold increase of T69 and C-191
alle... |
27,883 | [Effect of antiischemic therapy in immediate period after mammary coronary
bypass surgery on left ventricular contractility and conduit blood flow.
Randomized controlled study]. | AIM: To assess influence of 2-week course therapy with atenolol, nebivolol, and
verapamil on systolic and diastolic left ventricular function and mammary
coronary blood flow in early period after revascularization.
MATERIAL: Patients (n=113) after mammary coronary bypass grafting.
METHODS: Echocardiographic character... |
27,884 | [Dynamics of parameters of diastole and subendocardial right ventricular blood
flow in adult patients after correction of atrial septal defect]. | The study of intracardiac hemodynamics and subendocardial blood flow in 55
adults with atrial septal defect confirmed practical value of assessment of
myocardial contractility by long term catheterization of right cardiac chambers,
construction of right ventricular function curves and "pressure-volume"
diagrams. Si... |
27,885 | [Antiremodeling Activity of Nebivolol in Patients With Essential Hypertension
and Various Types of 4a/4b Polymorphisms of Endothelial NO Synthase Gene]. | Frequencies of alleles and genotypes of a polymorphic marker 4a/4b of eNOS gene
and association of this marker with parameters of hemodynamics, signs of left
ventricular hypertrophy and endothelial dysfunction were studied in 78 uzbek men
aged 50.5+/-9.5 years with stage I-II essential hypertension. Allele 4b and
g... |
27,886 | [Modern antidepressants in complex management of patients with hypertension and
concomitant affective disorders]. | According to results of multiple studies depression and anxiety are found in
more than 50% of patients with hypertension. Presence of affective disorders
elevates risk of progression of hypertension. That is why complex therapy
comprising antihypertensive drugs from various groups and antidepressants takes
on highe... |
27,887 | [Atorvastatin: lipid lowering activity, pleiotropic properties and efficacy in
prevention of atherosclerosis and coronary heart disease]. | The review presents data on pharmacological properties of atorvastatin, its
lipid lowering activity, and action on main mechanisms of atherogenesis.
Favorable pleiotropic effects of atorvastatin such as normalization of
endothelial function, antiinflammatory, antithrombotic and antioxidant activity
contribute to st... |
27,888 | [The problem of optimization in cardiology]. | Optimization is understood as choice of the best version out of the competitive
decisions. The strategy and tactics of prevention is presented from this point
of view. Optimization of diagnostic investigations is viewed from the positions
of continuum with quantitative assessment of results. Characteristics of loads... |
27,889 | [Long-Term Therapy With Indirect Anticoagulants in Patients With Nonvalvular
Atrial Fibrillation (Prospective Follow-Up Study). Part II. Effectiveness and
Safety]. | AIM: To assess efficacy and safety of long-term international normalized ratio
(INR) guided therapy with acenocoumarol in patients with nonvalvular atrial
fibrillation.
MATERIAL: Patients (n=100) with nonvalvular atrial fibrillation and at least 1
risk factor of thromboembolic complications.
METHODS: Ischemic stroke... |
27,890 | [Autoantibodies Against beta(1)-Adrenoreceptors in Patients With Cardiac Rhythm
Disorders. Prevalence and Possible Role in Development of Arrhythmia]. | AIM: To assess prevalence of autoantibodies against beta(1)-adrenoreceptors
(beta(1)-AR) in patients with arrhythmias of various etiology.
MATERIAL: Patients with arrhythmias (n=110, including 59 patients with primary
[idiopathic] electrical abnormalities, 33 - with chronic myocarditis and dilated
cardiomyopathy [DC... |
27,891 | [Prevalence of electrocardiographical signs of right ventricular arrhythmogenic
dysplasia]. | Right ventricular arrhythmogenic dysplasia (RVAD) is a state with high risk of
sudden death in young patients. Early diagnosis of RVAD can facilitate sudden
death prevention.
AIM: To assess prevalence of electrocardiographical signs of RVAD among children
with "idiopathic" tachyarrhythmias.
MATERIAL: Patients withou... |
27,892 | [Assessment of myocardial viability by dobutamine stress echocardiography in
patients with ischemic heart disease]. | Detection of viable (hibernating) myocardium is necessary for determination of
prognosis and tactics of treatment of patients with ischemic heart disease. For
detection of viable myocardium and investigation of possibilities of its
restoration 60 patients with ischemic heart disease (54 men, mean age 52+/-8
years) ... |
27,893 | [Effectiveness of early psychological rehabilitation among hospitalized patients
with ischemic heart disease]. | The subjects of the study were men and women (n=418) suffering from myocardial
infarction or angina pectoris and hospitalized in the Cardiological Clinic of
Kaunas Medical University during May-June, 2001. In order to assess the
possibility to apply measures of psychological rehabilitation in a hospital
setting, pa... |
27,894 | [Relationship Between Lipid Lowering and Changes of Hemostasis and Inflammation
During Use of Statins in Non-ST Elevation Acute Coronary Syndrome]. | AIM: To analyze relationship between changes of lipid levels and parameters of
hemostasis and inflammation in a previously reported comparative study of some
biological effects of pravastatin and atorvastatin in patients with non ST
elevation acute coronary syndrome (NSTEACS).
METHODS: Ninety aspirin and heparin tre... |
27,895 | [Impairment of cardiac sympathetic function in patients with acute myocardial
infarction and unstable angina]. | AIM: To assess the state of sympathetic innervation of the heart in patients
with acute coronary syndrome.
MATERIAL: Patients with Q-myocardial infarction (MI, n=36), non-Q-MI (n=13), and
unstable angina (UA, n=9).
METHODS: Each subject underwent single-photon emission computed tomography
(SPECT) and planar scintigr... |
27,896 | [Postinfarction left ventricular remodeling in patients with hypertension]. | 1-3 years after myocardial infarction 140 patients (66 with - group 1, and 74
without - group 2 - hypertension before infarction) were examined by
echocardiography. In group 1 concentric remodeling was found in 71.4% of
patients with postinfarction scar occupying </=25% of left ventricular area
(nonextensive scar) ... |
27,897 | [Effect of beta-Blocker Bisoprolol on Function of Hibernating Myocardium in
Patients With Chronic Heart Failure of Ischemic Etiology]. | AIM: To elucidate effect of beta-blocker bisoprolol on hibernating myocardium in
patients with congestive heart failure (CHF) of ischaemic etiology without
concomitant use of angiotensin converting enzyme inhibitors.
MATERIAL AND METHODS: Men (n=21, mean age 51,1+/-2,3 years) with NYHA class
II-III congestive heart ... |
27,898 | [Anticholinergic Effect of a New Antiarrhythmic Class III Drug RG-2]. | In experiments on isolated rat and rabbit right atrium, a new class III
antiarrhythmic drug RG-2 (0,01-1 microM) was shown to have anticholinergic
action competing with 0.2-1 mM carbachol. RG-2 (0.1-1 microM) produced
dose-dependent increase of APD90% in rat and rabbit atrial cells and had no
effects on other actio... |
27,899 | [Peripheral hemodynamics in neurocirculatory dystonia]. | AIM: To assess the state of peripheral hemodynamics in patients with
neurocirculatory dystonia and elucidate its relation to disease duration and
clinical presentation.
MATERIAL AND METHODS: Laser doppler flowmetry was used for the study of
microcirculation in 25 healthy subjects and 91 patients with neurocirculator... |
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