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27,600 | [High-resolution ECG in assessment of myocardial functional state in patients
with ischemic heart disease and resultant cardiac dilatation]. | High resolution signal-averaged ECG (SAECG), echocardiography and 24-hour Holter
ECG monitoring were used in the study of 30 patients (mean age 56-/+2 years)
with coronary heart disease and stable class II-IV angina (group 1) and 66
patients (mean age 45-/+1 years) with dilated cardiomyopathy of ischemic origin
(gr... |
27,601 | [24-hour blood pressure rhythm: clinical and predictive value]. | Clinical and predictive value of 24-hour blood pressure rhythm is reviewed.
Insufficient nocturnal blood pressure lowering induces augmented pressure load
on target organs. On the other hand it reflects dysregulatory changes due to
target-organ involvement. Lack of adequate nocturnal blood pressure lowering is
cons... |
27,602 | [Activity of blood platelets and functional state of endothelium in patients
with unstable angina with favorable and unfavorable outcome (prospective
study)]. | Functional activity of platelets (aggregation and plasma levels of soluble
P-selectin) and functional state of endothelium (antiaggregatory activity of
vessel wall - AAVW, cuff occasion test, and plasma content of von Willebrand
factor) were assessed in patients with unstable (n=41) and stable (n=19) angina
and hea... |
27,603 | [Proinflammatory cytokines and soluble intercellular adhesion molecule-1 in
ischemic heart disease]. | Blood serum levels of tumor necrosis factor alpha (TNF-alpha), interleukin 1beta
(IL-1beta) and soluble intercellular adhesion molecule-1 (sICAM-1) were measured
by ELISA in patients with stable and unstable angina. Levels of cytokines and
sICAM-1 were elevated in patients with stable and were even higher in patient... |
27,604 | [Relationship between parameters of heart rate variability, angiographical
severity of coronary atherosclerosis and functional class of angina in patients
with ischemic heart disease]. | AIM: To elucidate relationship between heart rate variability and severity of
coronary atherosclerosis.
MATERIAL: Seventy five patients with class I-IV angina subjected to coronary
angiography and 23 apparently healthy subjects of the same age without overt
coronary heart disease.
METHODS: Analysis of parameters of ... |
27,605 | [Atenolol induced bradycardia in patients with stable angina: effects on
exercise tolerance, myocardial perfusion and left ventricular contractility]. | AIM: To assess effects of atenolol-induced heart rate decrease on myocardial
perfusion, left ventricular contractility and tolerance to exercise in patients
with chronic coronary artery disease.
MATERIAL AND METHODS: Twenty eight men (mean age 54,5-/+9,2 years) with stable
class I-III angina and positive reproducibl... |
27,606 | [Dynamics of left ventricular remodeling in patients with acute myocardial
infarction]. | Dynamics of structural and functional left ventricular parameters was
investigated in 51 patients with acute anterior myocardial infarction by means
of serial (on days 1, 2, 3, 5, 7, 10 and 21 of infarction) echocardiographical
study. Increase of end-diastolic volume index relative to initial values became
signific... |
27,607 | [Peculiarities of blood pressure rhythms and blood pressure variability in
adolescents with hypertension (in accordance with twenty-four monitoring of
blood pressure)]. | Registration of 24-hour blood pressure in adolescents with and without
hypertension revealed active participation of sympathetic nervous system in
genesis of juvenile hypertension. Hypertension in adolescents was mainly
systolic, blood pressure elevation as a rule was accompanied by accelerated
heart rate and incre... |
27,608 | [Clinical effectiveness of beta-adrenoblockers and their effects on copulative
function in patients with hypertension]. | Twenty four hour blood pressure and ECG monitoring, assessment of sexual
function (questionnaires, penile artery Doppler flowmetry) were carried out in
male hypertensives treated with atenolol, metoprolol, or bisoprolol. Compared
with atenolol and metoprolol bisoprolol was found to be more effective and safe.
The u... |
27,609 | [Prevalence of electrocardiographic signs of pulmonary hypertension in a sample
of male population of Novosibirsk]. | Prevalence of ECG signs of right ventricular hypertrophy and pulmonary
hypertension was assessed in a representative sample (n=715) of nonorganized
male population (age 25-64 years) of Novosibirsk studied within a framework of
WHO MONICA project. Other methods of investigation included Rose questionnaire,
anthropom... |
27,610 | [Effect of adriamycin on expression and content of myocardial structural and
regulatory proteins]. | The biochemical and morphological study of the cytoskeleton and extracellular
matrix of rat heart was carried out after single injection of adriamycin (2.2 or
0.44 mg/kg). Hearts were taken for the study after 2 hours and 3 weeks after
injection. The light and electronic microscopy, immunohistochemical
determinatio... |
27,611 | [Angiotensin converting enzyme inhibitors in renal diseases]. | Chronic diffuse renal diseases, involvement of the kidney in systemic and
metabolic disorders are characterized by steady progression of renal pathology
with loss of functional nephrons, lowering of renal functions and gradual
development of chronic and eventually terminal renal failure. Basic mechanism of
progress... |
27,612 | [Relationship between myocardial viability and ventricular late potentials in
patients with history of myocardial infarction]. | AIM: To study relationship between presence and volume of viable myocardium and
registration of late ventricular potentials in patients with history of
myocardial infarction.
MATERIAL AND METHODS: High resolution ECG, dobutamine stress echocardiography
and Holter ECG monitoring were carried out 34 patients (mean age... |
27,613 | [Complex of factors affecting heart rate dispersion in survivors of myocardial
infarction]. | AIM: To establish complex of independent variables related to parameters of
heart rate variability in patients with postinfarction cardiosclerosis.
MATERIAL: Seventy four patients (age 49-/+0.8 years) were studied in 6 months or
later after myocardial infarction. Temporal and spectral characteristics of
heart rate v... |
27,614 | [Psychological traits and quality of life of patients with hypertension and
metabolic risk factors]. | Psychological status and quality of life were assessed in 75 patients with mild
and moderate hypertension and metabolic disturbances. Patients with hypertension
and metabolic risk factors compared with patients without these factors were
characterized by higher frequency of neurotic disorders, worse quality of life ... |
27,615 | [Effect of amiodarone on autonomic status and its efficacy in the treatment of
different variants of paroxysmal atrial fibrillation]. | Association of autonomic status and efficacy of therapy with amiodarone was
studied in 90 patients with paroxysmal atrial fibrillation of ischemic (n=45,
mean age 62 years) and nonischemic (n=45, mean age 38 years) origin. Autonomic
status was assessed by measurement of heart rate variability.
Electrophysiological ... |
27,616 | [Nitric oxide activates Ca2+ activated potassium current in rat tail artery
smooth muscle cells via cGMP-dependent mechanism]. | Mechanisms of nitric oxide (NO) action on K(Ca) channels were investigated using
patch-clamp technique and freshly isolated smooth muscle cells from rat tail
artery. In whole-cell experiments, the outward current was increased
6,64-/+0,72-fold (n=10) by 100 microM sodium nitroprusside (SNP), which was
significantly... |
27,617 | [Cardiological aspects of the antiphospholipid syndrome. Part I. Valvular
lesions in the primary and secondary antiphospholipid syndrome and systemic
lupus erythematosus]. | AIM: To assess prevalence of cardiac valvular lesions in patients with primary
(P) antiphospholipid syndrome (APLS) and systemic lupus erythematosus (SLE) with
and without secondary APLS.
MATERIAL AND METHODS: Patients with PAPLS (n=56, 15 men and 41 women), SLE and
APLS (n=88, 23 men, 65 women) and SLE without APLS... |
27,618 | [Invasive cardiology--focus on restenosis. Part I]. | In-stent restenosis is mainly caused by neointima proliferation and represents a
pathological process which histology is different from that of restenosis after
balloon angioplasty. Frequency of in-stent restenoses increases parallel with
progressively increasing number of procedures of coronary stenting. The review... |
27,619 | [Identification of slow anterograde conduction of excitation in patients with
paroxysmal reciprocal atrioventricular nodal tachycardia]. | Basing on results of examination of a cohort of patients with typical paroxysmal
reciprocal atrioventricular tachycardia a group of patients with continuous
curve of anterograde conduction was distinguished. The use of incremental doses
of adenosine triphosphate (ATP) during transesophageal atrial pacing allowed in ... |
27,620 | [Dynamics of parameters of heart rate variability in patients with ischemic
heart disease after direct myocardial revascularization]. | AIM: To study dynamics of parameters of heart rate variability (HRV) in patients
with ischemic heart disease after direct myocardial revascularization.
MATERIAL AND METHODS: Electrocardiography (ECG), 24 hour Holter ECG with
spectral and temporal analysis of 24-hour HRV, as well as echocardiography
(Echo) and stress... |
27,621 | [Heart rate variability before and after coronary artery bypass surgery in
patients with ischemic heart disease]. | Short term heart rate variability (HRV) was studied in 44 patients before, in 2
weeks and 2 months after coronary artery bypass grafting (CABG). Prior to
surgery the patients were divided into 2 groups: with normal and substantially
lowered HRV parameters. In 2 weeks after CABG lowering of HRV was registered in
all... |
27,622 | [Influenza virus infection in progressing atherosclerosis]. | AIM: To study relationship between influenza virus infection and activity of
clinical presentations of atherosclerosis.
METHODS AND RESULTS: Average blood level of IgG to influenza A virus was
significantly higher in patients with progressing forms of ischemic heart
disease then in patients without objective signs o... |
27,623 | [Tolerability and efficacy of retard form of indapamide in the treatment of
hypertension in elderly patients (results of multicenter open non-comparative
trial in Russian program ARGUS)]. | Open noncomparative multicenter study of tolerability and efficacy of a retard
form of indapamide (1.5 mg o.d. for 3 months) in patients older then 55 years
was conducted in 14 centers in Russia. Numbers of patients included into was
analysis of safety and tolerability were 1277 and 1121, respectively. After 3
mont... |
27,624 | [The state of microcirculation in hypertensive disease (essential
hypertension)]. | Skin microcirculation was studied by laser doppler flowmetry in 149 patients
with essential hypertension (92 men, 67 women; mean age 50.1+/-4.9 years) and in
25 normotensive controls. In patients with hypertension prevailed pathological
hemodynamic types of microcirculation. Hyperemic, spastic and congestive types
... |
27,625 | [The use of enalaprilat for the treatment of uncomplicated hypertensive crises
in patients with hypertensive disease (essential hypertension)]. | When used for the treatment of hypertensive crises enalaprilat produced
pronounced lowering of both systolic and diastolic blood pressures. Lowering of
blood pressure was accompanied by regression of clinical symptoms. There were no
episodes of excessive blood pressure drop. The use of enalaprilat was associated
wi... |
27,626 | [Blood pressure profile in patients with hyper- and hypotension: effect of
physiological stresses]. | Responses to physiological stresses, relationship between character and severity
of these reactions and parameters of 24-hour blood pressure (BP) profile were
studied in patients with arterial hyper- and hypotension. Disturbed regulation
of BP in hyper-, and hypotension was associated not only with pronounced
spont... |
27,627 | [Effect of hormone replacement therapy on blood serum lipids in postmenopausal
women with type 2 diabetes]. | There are limited data concerning influence of hormone replacement therapy (HRT)
on lipid profile in women with type 2 diabetes. Aim of the study was to compare
changes of blood lipids during HRT in postmenopausal women with and without type
2 diabetes. Seventy seven women included in the study were assigned to 1 of... |
27,628 | [C-reactive protein--marker of inflammation in atherosclerosis (new data)]. | According to contemporary conceptions two interrelated processes underlie
development and progression of atherosclerosis: changes of metabolism and
transport of lipids inflammation of vessel wall. Vascular inflammation plays
fundamental role in destabilization of atherosclerotic plaque and thus in
development of va... |
27,629 | [Interaction of angiotensin converting enzyme inhibitors with nonsteroidal
antiinflammatory drugs]. | Analysis of results of randomized controlled studies revealed pronounced
attenuation of vasodilating, natriuretic, and cardioprotective effects of
angiotensin converting enzyme inhibitors (ACEI) by concomitant use with of
indomethacin and aspirin in patients with hypertension, chronic heart failure,
and acute myoca... |
27,630 | [Pravastatin: pharmacological action, pleiotropic effects and efficacy in
prevention of atherosclerosis]. | This literature review presents data on pharmacological action of pravastatin,
its lipid lowering activity, and influence on main mechanisms of atherogenesis.
Beneficial pleiotropic (nonlipid) effects of pravastatin: normalization of
endothelial function, antiinflammatory action, antiischemic- and antithrombotic
ef... |
27,631 | [Antiarrhythmic drug allapinin: review of results of clinical investigation]. | Antiarrhythmic drug allapinin has been used in clinical practice for a long time
but data of investigation of its effects and mechanism of action are scanty. The
aim of this review is to summarize results of clinical studies of allapinin
supplementing them with personal unpublished data. The review embraces
pharmac... |
27,632 | [The use of a beta-blocker esmolol in patients with acute myocardial infarction
treated with streptokinase]. | Infusion of esmolol (50-300 mcg/kg/min, mean 119-/+75.5 mcg/kg/min, average
duration 3.2-/+1.22 h)) was carried out in 49 streptokinase treated patients
within 6 hours of myocardial infarction. Infusion was associated with slowing of
heart rate and lowering of mean dynamic systolic blood pressure (by 22%). No
chang... |
27,633 | [Pharmacodynamics, safety, and clinical effects of a novel glycoprotein IIb/IIIa
antagonist framon during high risk coronary angioplasty]. | Preparation framon [F(ab')2 fragments of the anti-glycoprotein (GP) IIb/IIIa
monoclonal antibody (FRaMon)] blocks fibrinogen binding to GP IIb/IIIa and
platelet aggregation. Dynamics of platelet aggregation inhibition, safety, and
clinical effects of framon were studied in high-risk coronary angioplasty.
Twenty sev... |
27,634 | [Heart fatty acid binding protein in patients with ST-elevation acute coronary
syndrome hospitalized within 6 hours after onset of pain]. | AIM: To compare diagnostic value of a novel marker of myocardial necrosis heart
fatty acid binding protein (FABP) with that of troponin I (TnI) and total
creatine kinase (CK) in patients admitted early after onset of ST-elevation
acute coronary syndrome.
MATERIAL: Fifty seven patients with ST-segment elevations just... |
27,635 | [Trimetazidine in pectoris patients older than 65 years with stable angina]. | AIM: To study efficacy of trimetazidine including action on quality of life in
patients over 65 years of age with stable angina pectoris.
MATERIAL: Seventy two patients (75% men, age 65-80 years) with stable class
II-III angina not completely controlled by baseline conventional combined
antianginal therapy (nitrates... |
27,636 | [Blood lipids in offsprings of patients with ischemic heart disease]. | AIM: To elucidate correlations between characteristics of lipid metabolism in
patients with ischemic heart disease and their offsprings.
MATERIAL: Patients with overt ischemic heart disease (probands, n=24, mean age
53-/+1.9 years), their first (n=25, mean age 25.7-/+1.8 years) and second
generation (n=20, mean age ... |
27,637 | [Assessment of right ventricular function in patients with congenital heart
defects with pulmonary hypertension. The role of some parameters of
hemodynamics]. | Intracardiac hemodynamics was studied in 46 patients with intraventricular
septal defect and 32 patients with incomplete atrioventricular canal. The study
confirmed practical value of assessment of contractility of right ventricular
myocardium basing on information obtained during prolonged catheterization of
the r... |
27,638 | [Prevalence of detection of autoantibodies to beta-1 adrenoreceptors in patients
with myocarditides and cardiomyopathies]. | BACKGROUND: Autoantibodies to the second extracellular loop of a cardiac
beta1-adrenoreceptors has been detected in some patients with cardiomyopathies
and myocarditides. In animal experiments these autoantibodies have been shown to
cause reduction of myocardial contractility.
AIM: To estimate prevalence of detectio... |
27,639 | [Clinical characteristics of hypertensive disease in patients with alexithymia]. | AIM: To study hemodynamics and metabolism in patients with hypertensive disease
and various severity of alexithymia.
MATERIAL AND METHODS: Psychological testing was included into complex
examination of 202 patients with stage II hypertensive disease.
RESULTS: Patients with alexithymia had longer duration of hypertens... |
27,640 | [Does "pulmogenic hypertension" exist?]. | Validity of criteria of so called "pulmogenic hypertension" in chronic
obstructive pulmonary diseases was assessed with the use of a questionnaire and
simultaneous 24 hour monitoring of blood pressure and peak expiratory rate in 80
and 28 patients, respectively. This method of bifunctional monitoring allowed to
stu... |
27,641 | [Contemporary approaches to diagnosis and management of chronic heart failure
(summary of the American College of Cardiology/American Heart Association
Guidelines)]. | ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in
the Adult are summarized in detail. According to statements of these Guidelines
most patients with chronic heart failure as a rule should receive combination of
representatives of 4 different drug classes - diuretic, angiotensin convert... |
27,642 | [Preventing of stroke by antihypertensive drugs: potential and limitations]. | Analysis of controlled randomized studies of efficacy of antihypertensive drugs
in primary and secondary prevention of stroke is presented. Basing on this
analysis a conclusion is made that in patients with hypertension representatives
of all 4 main classes of antihypertensive drugs prevent stroke with similar
effi... |
27,643 | [Clinical sequelae of tissue angiotensin converting enzyme inhibition:
practicability of use in ischemic heart disease]. | Harmonic combination of efficacy and safety allowed angiotensin converting
enzyme inhibitors (ACEI) to conquer popularity among physicians in the treatment
of hypertension, heart failure, myocardial infarction, diabetic and non-diabetic
nephropathy. This multiprofile application is determined by their action not
on... |
27,644 | [Apheresis of immunoglobulins - new approach to the treatment of severe dilated
cardiomyopathy]. | Two courses of immunoadsorption with 'Ig Adsopak' were used in the treatment of
a patient with dilated cardiomyopathy (DCM) during which all class G and
partially class M and A immunoglobulins were removed. Every course consisted of
5 daily procedures and resulted in removal of 98% of immunoglobulins. This was
asso... |
27,645 | [Lipoprotein (a) and ischemic heart disease in patients with hypertensive
disease]. | Relationship between level of lipoprotein (a) and presence of ischemic heart
disease (IHD) was studied in 191 patients with hypertensive disease (essential
hypertension) (112 men, 79 women, age 56.9-/+10.6 years) and 33 patients with
normal blood pressure (23 men, 10 women, age 50.8-/+11.0 years). Concentration
of ... |
27,646 | [Dynamics of rates of fatal and nonfatal complications of hypertension in a
population of workers subjected to occupational vibration (15-year follow-up)]. | Prospective monitoring of fatal and nonfatal myocardial infarctions and strokes
was carried out in a population of workers with professional exposure to
vibration. Duration of monitoring was 15 years. In the end of this period
implementation of a program of preventive intervention was associated with
lowering of ra... |
27,647 | [Effects of nebivolol on microcirculation, platelet aggregation and blood
viscosity in patients with essential hypertension]. | AIM: To assess effects of a selective beta1-adrenoreceptor blocker acting in
part via nitric oxide nebivolol on microcirculation, platelet aggregation and
blood viscosity.
MATERIAL: Thirty patients with mild-to-moderate essential hypertension (mean age
54,1-/+9,3 years).
METHODS: Ambulatory blood pressure monitoring... |
27,648 | [Gender differences in the state of the system of hemostasis in patients with
ischemic heart disease]. | Levels of fibrinogen, von Willebrand factor, d-dimer, antithrombin III, protein
C, plasminogen, and plasminogen activator inhibitor were measured in 62 men and
37 women with ischemic heart disease before and after 20-min venous occlusion.
Women compared with men had higher baseline levels of fibrinogen (4.046-/+0.17... |
27,649 | [Prospective analysis of conservative treatment of acute coronary syndrome]. | The in-hospital and intermediate outcomes in 341 patients with acute coronary
syndrome treated with conservative (non-invasive) interventions were analysed.
The coronary reperfusion was achieved in 59% patients with acute myocardial
infarction (MI) treated with thrombolysis, but in 27% patients with MI treated
only... |
27,650 | [Results of stenting and surgical treatment in patients with ischemic heart
disease and multivessel coronary artery involvement]. | Efficacy of surgical and endovascular (with the use of stents) methods of
treatment was assessed in 56 patients with ischemic heart disease and double and
triple vessel involvement. Coronary artery bypass grafting (CABG) was carried
out in 31, implantation of stents - in 25 patients. Clinical factors used for
asses... |
27,651 | [Antihypertensive drugs and malignant neoplasia]. | Analysis of epidemiological, cohort and randomized studies of antihypertensive
drugs containing reports of development of malignant neoplasms shows that long
term use of some antihypertensive drugs while preventing cardiovascular
complications has been associated with increased risk of malignancies. Most
convincing... |
27,652 | [The no-reflow phenomenon and its clinical significance]. | The no-reflow phenomenon is characterized by inadequate myocardial perfusion
without angiographic manifestations of mechanical vascular occlusion. The
phenomenon occurs after coronary vascular interventions (coronary angiography,
percutaneous coronary angioplasty, stenting, coronary artery bypass surgery).
The deve... |
27,653 | [Emerging problems of medical ethics in Russia: medical practice and research]. | The problem of maintenance of integrity of medical profession is rarely
discussed in Russia. Meanwhile the following pressing challenges emerge within
the medical community in this country: tolerant attitude to violations of
ethical principles and falsification in research, incompetence and deceit in
practical work... |
27,654 | [Feasibility of implementation of guidelines for the management of acute
coronary syndrome in cardiac unit of a community hospital]. | AIM: To assess feasibility of implementation of Guidelines of Russian Society of
Cardiology (RSC) on the management of non ST elevation acute coronary syndrome
(adaptation of Guidelines of the European Society of Cardiology) in an ordinary
noninvasive community hospital.
METHODS: Retrospective analysis of inhospital... |
27,655 | [Thrombolytic therapy of acute myocardial infarction in elderly patients.
Immediate and long-term remote prognosis]. | AIM: To study effects of thrombolytic therapy in elderly patients.
MATERIAL AND METHODS: One hundred twenty three patients with acute myocardial
infarction were admitted within first 12 hours of myocardial infarction, 66 of
them were subjected to thrombolytic therapy with streptokinase (group 1) while
57 were not be... |
27,656 | [Prognostic value of cardiac troponin I in patients with non-ST elevation acute
coronary syndrome]. | AIM: To elucidate relationship between initial blood levels of troponin I and
occurrence of such events as death, myocardial infarction, coronary artery
bypass surgery, and angioplasty in patients with non-ST elevation acute coronary
syndrome.
MATERIAL: One hundred one patients aged 32-78 years admitted to coronary ... |
27,657 | [Fatal and nonfatal cardiovascular complications in patients with essential
hypertension (hypertensive disease) during follow-up for many years]. | Fatal and nonfatal complications (stroke, myocardial infarction, chronic heart
failure, sudden coronary death, chronic renal insufficiency) were registered
during long term follow-up of 529 patients with hypertensive disease and results
were analyzed retrospectively. Duration of ambulatory treatment in two thirds of... |
27,658 | [Effect of therapy with lisinopril on the state of cerebral blood flow in women
with hypertension in peri- and postmenopause]. | Blood flow in extra and intracranial arteries was assessed by doppler ultrasound
in 26 hypertensive women without history of stroke. Studies were performed
before treatment, after acute test with lisinopril and in 1 month of therapy
with lisinopril. Baseline investigation revealed changes of velocity
characteristic... |
27,659 | [Long term use of a non-selective beta-blocker with vasodilating properties
carvedilol in patients with severe heart failure]. | Results of drug treatment of 51 patients (41 men, 10 women) aged 35-86 years
(mean age 62 years) included into COPERNICUS trial are presented. All patients
had compensated NYHA class IV chronic heart failure and left ventricular
ejection fraction less than 25%. For at least 2 months the patients received
therapy wi... |
27,660 | [Comparative analysis of results of two techniques of ablation for typical
atrial flutter]. | AIM: To compare efficacy of two techniques of ablation for typical atrial
flutter: 'old' which end point was impossibility of arrhythmia reinduction and
'novel' aimed at change of sequence of right atrial excitation during coronary
sinus ostium pacing for verification of isthmus block after ablation of the
inferior... |
27,661 | ['Uninterrupted' anterograde atrioventricular excitation conduction in patients
with paroxysmal reciprocal atrioventricular nodal tachycardias]. | Different variants of anterograde atrioventricular conduction of excitation were
distinguished basing on data obtained from 150 patients with paroxysmal
reciprocal atrioventricular nodal tachycardias. Excitation conduction during
programmed and accelerating atrial transesophageal pacing allowed to assess
characteri... |
27,662 | [Assessment of the use of various cardiac pacing modes for selection of
antiarrhythmic therapy for prevention of recurrent attacks of atrial
fibrillation and flutter]. | AIM: To determine optimal mode of transesophageal pacing for selection of
appropriate antiarrhythmic therapy for prevention of attacks of atrial
fibrillation and flutter in patients with ischemic heart disease.
MATERIAL AND METHODS: Two hundred eighteen patients with ischemic heart disease
and attacks of atrial fibr... |
27,663 | [Comparative assessment of different types of adaptational protection of the
myocardium during stress]. | AIM: To study in rats effects of 3 types of adaptation on structural
rearrangement of myocardium during stress.
METHOD: Corrosion preparations of coronary vessels, morphometry of focal lesions
of cardiomyocytes and correlation analysis of relationships between data
obtained by these methods.
RESULTS AND CONCLUSIONS:... |
27,664 | [Synthesis of nitric oxide and development of atherosclerosis]. | The paper reviews data on the possible role of malfunction of nitric oxide (NO)
synthesis in pathogenesis of atherosclerosis. The singularities of NO synthesis,
types of enzymes catalyzing this reaction (a set of NO-synthases), and some
possible aspects of regulation of their activity are briefly surveyed. Available... |
27,665 | [Cardiovascular complications of type 2 diabetes]. | Cardiovascular complications due to micro- and microangiopathy are main causes
of death of patients with type 2 diabetes. Principal role in development of
these complications belong to hyperglycemia which triggers such pathological
processes as endothelial dysfunction, oxidative stress, impairment of hemostasis
and... |
27,666 | [Assessment of efficacy of treatment of patients with chronic ischemic heart
disease]. | The lecture summarizes data on approaches to organization of studies in which
evidence based data on efficacy and safety of therapy of patients with ischemic
heart disease can be obtained. Some novel approaches to improvement of quality
of assessment of benefits of treatment are suggested. It is stressed that
resul... |
27,667 | [Depression--a novel risk factor of ischemic heart disease and predictor of
coronary death]. | According to results of recent prospective studies depression is an independent
risk factor of ischemic heart disease and should be considered together with
such acknowledged risk factors as dyslipidemia, hypertension and smoking.
Possible pathophysiological mechanisms of relationship between depression and
ischemi... |
27,668 | [Some results and perspectives of heart failure research]. | Heart failure is a frequent often in the practice of a cardiologist but data on
its actual incidence are inconsistent. This can be explained by variations in
methodological approaches. Screening studies require simple easily obtainable
and safe techniques capable to characterize activity of a patient. Their results ... |
27,669 | [Effect of long-term myocardial unloading with beta1-adrenoblocker atenolol on
the state of the left ventricle in patients with moderate ischemic dysfunction
of the heart as shown by doppler echocardiography]. | Effects of 12-month therapy with a beta1-adrenoblocker atenolol on the process
of late postinfarction remodeling of the heart and parameters of intracardiac
hemodynamics were assessed in an open noncomparative study on 55 survivors of
macrofocal myocardial infarction. Therapy with atenolol was associated with: (1)
... |
27,670 | [Trimetazidine in correction of chronic heart failure in patients with ischemic
heart disease]. | Twenty patients with NYHA class II-IV heart failure and ejection fraction below
40% received standard therapy (control period) or standard therapy plus open
trimetazidine (20 mg t.i.d.) for 3 months in a cross-over design. Therapy with
trimetazidine was associated with attenuation of clinical signs of heart failure ... |
27,671 | [Coronary stenting in acute myocardial infarction complicated with cardiogenic
shock]. | AIM: To assess immediate and long-term results of urgent coronary stenting in
patients with cardiogenic shock.
MATERIAL AND METHODS: Twenty three patients (15 men, 8 women mean age 58-/+12
years) with myocardial infarction and cardiogenic shock treated with
vasopressors and intraaortic balloon pumping (IABP). Culpri... |
27,672 | [Stratification of patients with hypertension and selection of antihypertensive
therapy]. | Patients with hypertension (78 men, 113 women aged 20-73 years) were stratified
according to risk of development of cardiovascular complications. In low and
moderate risk patients (n=31) with borderline hypertension, dyslipidemia and
pronounced obesity mainly non-drug measures were employed directed at lowering
of ... |
27,673 | [Effect of mexidol on oxidative stress in cerebral variant of hypertensive
crisis]. | Parameters of oxidative stress were studied in 44 patients with grade II-III
essential hypertension and cerebral variant of hypertensive crisis. All patients
received antihypertensive treatment. Mexidol was administered intravenously (300
mg o.d.) for 7 days starting with the second day of a hypertensive crisis.
Co... |
27,674 | [NOS3 gene polymorphism and left ventricular hypertrophy in patients with
essential hypertension]. | One hundred nine patients with essential hypertension were studied (50 male and
59 female, mean age - 62,6-/+1,08 years). Seventy six patients had left
ventricular hypertrophy measured by echocardiography. NOS3 polymorphisms
(Glu298Asp and ecNOS4a/4b) were studied by PCR. In patients without left
ventricular hypert... |
27,675 | [Use of myocardial tissue Doppler imaging in cardiology]. | Tissue Doppler imaging is a new promising method of non-invasive assessment of
cardiac function. This method has heralded a renaissance of interest in
longitudinal ventricular function. There is evidence that long-axis function is
a more sensitive index of myocardial contractility than conventional
echocardiographi... |
27,676 | [Adverse effects of angiotensin II type 1 receptor blockers ]. | Angiotensin II type 1 receptor blockers belong to a novel class of
cardiovascular agents that is characterized by excellent tolerance. The overall
rate of their side effects is similar to that of placebo. Specific nonproductive
cough is much less common during treatment with angiotensin II blockers compared
with an... |
27,677 | [Reflected wave and isolated systolic hypertension: problems of pathogenesis and
therapy]. | The value of reflected (tidal) wave amplitude in the pathogenesis of isolated
systolic hypertension (ISH) is discussed and main characteristics of elastic
properties of arteries (compliance, distensibility, rigidity, pulse wave
velocity, and amplitude of reflected wave) are considered. In ISH systolic and
pulse blo... |
27,678 | [Clinical and angiographical results of the use of the EPHESOS stent in patients
with coronary artery atherosclerosis]. | The Ephesos is a new balloon-expandable, stainless steel, tubular stent with
multicellular design. This open nonrandomized study assesses the immediate and
long-term clinical and angiographic outcomes after Ephesos implantation in
patients with native coronary artery disease. The Ephesos was implanted in 168
patien... |
27,679 | [C-reactive protein as possible early prognostic marker of restenosis
development in coronary artery stents]. | AIM: To study possible link between inflammatory response of the body to stent
implantation and development of instent restenosis.
METHODS: C-reactive protein (CRP) was determined in 24 patients subjected to
coronary stenting. Coronary angiography was repeated in 7.1-/+0.68 months after
initial procedure.
RESULTS: A... |
27,680 | [Changes of parameters of the functional state of the organism and oxidative
stress in patients after surgical revascularization at early stage of
restorative treatment]. | Early complex restorative treatment with individualized aerobic physical
exercise in 2-4 weeks after surgical myocardial revascularization significantly
increased physical working capacity and cardiorespiratory reserve of the body.
Pronounced oxidative stress which had been present after myocardial
revascularizatio... |
27,681 | [Comparative analysis of parameters of corrected and uncorrected QT-interval
dispersion of magneto-, electrocardiography and isomagnetic maps in patients
with ischemic heart disease]. | AIM: To compare possibilities of magnetocardiography (MCG) and
electrocardiography for assessment of regional dispersion of ventricular
recovery time using parameters of corrected and uncorrected QT-interval
dispersion (DQTs and DQT).
MATERIAL: Twenty three patients with class II angina pectoris including 11
patien... |
27,682 | [Assessment of efficacy and safety of nebivolol in patients with stable effort
angina]. | AIM: To study efficacy and safety of nebivolol in patients with stable angina
pectoris.
MATERIAL: Twenty patients with stable effort angina pectoris and positive
exercise test without contraindications to beta-blockers, signs of NYHA class
III-IV heart failure, and obstructive lung disease. After 5-7 days of control... |
27,683 | [Antiischemic efficacy of trimetazidine in patients with ischemic heart disease,
stable angina pectoris and disturbances of carbohydrate metabolism]. | AIM: To compare antiischemic effects of trimetazidine in patients with stable
angina pectoris with and without disturbances of carbohydrate metabolism.
MATERIAL: Patients with ischemic heart disease, stable class II-III angina
pectoris and reproducible positive results of on-treatment exercise tests (n=40,
mean age ... |
27,684 | [The role of heredity and environment in formation of 24-hour blood pressure
profile in patients with hypertension (a study of twins)]. | Twenty four hour blood pressure monitoring was carried out in 64 sex concordant
pairs of monozygotic and dizygotic hypertensive twins (mean age 52.7-/+3.2
years). Clinico-genetic analysis of quantitative parameters showed that during
day awake time systolic, diastolic, and mean blood pressures were mainly
determine... |
27,685 | [Effect of long term therapy with captopril on dopplerographic parameters of
intrarenal blood flow and renal function in patients with hypertension and
diabetes]. | Effect of 9-12 month treatment with captopril on dopplerographic parameters of
intrarenal blood flow and renal function was studied in 30 hypertensive
diabetics without clinical signs of nephroangiopathy. There was an
interrelationship between strict blood pressure (BP) control (average 24-hour BP
below 135/83) and... |
27,686 | [Angiotensin II receptor blocker telmisartan: effect on 24-hour blood pressure
profile and left ventricular hypertrophy in patients with hypertension]. | AIM: To study antihypertensive efficacy of monotherapy with telmisartan and its
action on left ventricular myocardium remodeling in patients with hypertension.
MATERIAL AND METHODS: Telmisartan (40-80 mg/day) was given for 24 weeks to 24
patients aged 37-69 years with I-II degree of blood pressure (BP) elevation and ... |
27,687 | [Recovery of left atrial function after cardioversion of atrial fibrillation:
the role of some clinical and echocardiographical factors]. | Sinus rhythm was restored in 102 patients with atrial fibrillation.
Cardioversion was spontaneous (n=6), pharmacological (n=35), and electrical -
early (n=46) or postponed because of necessity of full anticoagulation (n=15).
Irrespective of method of cardioversion all patients had signs of atrial
stunning. Doppler ... |
27,688 | [Prevalence of ischemic heart disease and mortality among kaunas population aged
35-64 years in the prospective study]. | MONICA (MONItoring trends and determinants of CArdiovascular diseases) study was
carried out in Kaunas in 1983-1993 in three random samples of population aged
35-64 (overall 2694 men and 2801 women). The prevalence of previous MI among men
was higher than among women in the first and in the third surveys (2,2 and 1,... |
27,689 | [Prognostic value of duration and variability of QT and RR intervals in general
population of Novosibirsk]. | Increased duration and dispersion of QT interval and lowered variability of RR
interval are considered to be probable precursors of dangerous ventricular
arrhythmias and sudden death. Standard epidemiological methods were used for the
study of a representative sample of nonorganized male population (age 25-64
years... |
27,690 | [Effect of atorvastatin on endothelial function in patients with familial
hypercholesterolemia]. | AIM: To study the influence of treatment with HMG-CoA reductase inhibitor
atorvastatin on endothelial function in patients with familial
hypercholesterolemia type IIa.
MATERIALS AND METHODS: Sixteen patients (5m/11w, 51-/+3 years) with familial
hypercholesterolemia were studied before and after 3 months of therapy w... |
27,691 | [Atherosclerosis in victims of cancer]. | Atherosclerotic changes in aortas and coronary arteries of victims of cancer
were investigated within framework of 2 epidemiological studies of men aged
20-59 years in Malmo, Prague, Riga, Tallin, Yalta and of women aged 40-59 years
in Malmo, Riga and Yalta conducted in 1963-1966 (first study) and 1985-1989
(second... |
27,692 | [Correction of atherogenic exogenously-induced postprandial hyperlipidemia with
pravastatin]. | Effect of an HMG-CoA reductase inhibitor pravastatin on atherogenic changes in
the lipid transport system during postprandial hyperlipidemia immediately after
ingestion of fatty meal was studied in patients with coronary heart disease and
fasting hyperlipidemia. Treatment with pravastatin (20-40 mg/day for 3 months)... |
27,693 | [Simvastatin in management of patients with primary hypercholesterolemia:
tolerability and efficacy of daily doses 10-80 mg]. | AIM: To analyze retrospectively data on lipid lowering efficacy, tolerability
and safety of different doses of simvastatin in patients with primary
hyperlipidemia.
MATERIAL AND METHODS: Thirty five patients (mean age 54.9-/+8.5 years, 15 men,
20 women) received simvastatin for 3-6 months in doses 10 (n=12), 20 (n=8)... |
27,694 | [Stress-ultrasound study of hemodynamic reserve of aortic compression chamber in
atherosclerosis: effect on coronary blood flow]. | AIM: To study the role of hemodynamic reserve of aortic compression chamber
(ACC) in compensation of coronary blood flow during stress.
MATERIAL: Ninety three subjects (78 men and 15 women) including 74 patients with
chronic ischemic heart disease (mean age 50-/+7 years) and 19 healthy volunteers
(mean age 45-/+5 ye... |
27,695 | [FLAG--a program of achievability of target blood pressure levels during
treatment of patients with hypertension with fosinopril]. | The Program FLAG was initiated by the Scientific Society of Arterial
Hypertension in order to assess achievability of WHO/ISH target blood pressure
(BP) levels in conventional ambulatory practice. Overall 2829 patients (mean age
53.1 years, 65% women) were enrolled in 17 cities of 5 regions in Russia.
Nineteen, 68,... |
27,696 | [The value of blood pressure self-measurement by patients with hypertension]. | Blood pressure (BP) self-measurement (SM) is a promising method of investigation
of patients with hypertension capable to provide information unobtainable
neither with traditional office measurements nor with 24-hour BP monitoring.
Advantages of BPSM are as follows: accessibility, low effect of anxiety on
results o... |
27,697 | [Diagnostic value of ventricular late potentials, heart rate variability and QT
dispersion in patients with acute myocardial infarction]. | Late ventricular potentials (LVP), heart rate variability (HRV) and dispersion
of QT interval (QTd) were studied in 91 patients with myocardial infarction with
various ventricular arrhythmias. Patients with episodes of sustained ventricular
tachycardia (group 4) had the following characteristics: prevalence of LVP
... |
27,698 | [The use of a program of medical and psychological support after coronary artery
bypass surgery in patients with ischemic heart disease]. | The paper contains analysis of results of restorative treatment in a sanatorium
and subsequent ambulatory care for 1 year of 167 patients after coronary artery
bypass surgery. All patients received similar curative and preventive aid, 127
patients in addition participated in a special program of medical and
psychol... |
27,699 | [The use of positron emission tomography for noninvasive diagnosis of
mitochondrial dysfunction and assessment of myocardial compensatory reserve in
children with cardiomyopathies]. | BACKGROUND: Recent experimental and clinical studies have shown that
cardiomyopathy (CMP) can be associated with disorders of oxidative metabolism in
cardiomyocyte mitochondria. These disorders are connected with deficit of
enzymes and complexes of electron transfer chain, and can constitute
pathogenetic base of th... |
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