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29,400 | [Portal vein thrombosis in HIV-infected patients: report of four cases]. | Portal vein thrombosis (PVT) seems rare among HIV infected patients. Even though, the report of such cases is of great interest because it may help to determine the factors of occurrence. We describe cases of PVT in 4 HIV-infected men, aged 32 - 64. Two of them were co-infected with hepatitis C virus (HCV). The four pa... |
29,401 | Tricaprylin microemulsion for oral delivery of low molecular weight heparin conjugates. | Heparin is available to patients only by parenteral administrations due to its low oral bioavailability. For the oral delivery of low molecular weight heparin (LMWH), LMWH-DOCA was synthesized by chemical conjugation of LMWH and deoxycholic acid (DOCA) and this conjugate was formulated in a microemulsion system. The co... |
29,402 | Lower extremity arterial and venous ulcers. | The prevalence of peripheral arterial disease in the general population is high, but the awareness of primary care providers of the disease process is low. The disease is not recognized by primary care providers. Early recognition and treatment of venous diseases that progress to postphlebotic syndrome, such as after a... |
29,403 | [Sepsis-associated coagulation disorders]. | Coagulation activation with intravascular fibrin formation is a general finding in patients with sepsis. Low coagulation factors may be caused by disseminated intravascular coagulation, as well as by loss of plasma and impaired hepatic synthesis in the course of sepsis. The leading clinical symptom in consumption coagu... |
29,404 | [Recurring pulmonary embolism despite the presence of a vena cava filter: a case report from the CNHU Cotonou-Benin]. | A 50-year-old man presents several clinical signs of pulmonary embolism, but this diagnosis was excluded due to the lack of venous thrombosis of the lower limbs and because the presence of a vena cava filter. The same signs reoccurred a few months later, leading to the diagnosis of venous thrombosis of the lower limbs ... |
29,405 | [When should a myeloproliferative syndrome be suggested in vascular medicine?]. | Thrombotic events are frequent in polycythemia vera (PV) and in essential thrombocythemia (ET). The frequency of thrombotic complications at presentation of PV and ET is nearly 50%. The spectrum of thrombotic complications is broad: thrombosis of arteries, veins and microvessels have been reported. Venous thrombosis ca... |
29,406 | Home therapy for deep vein thrombosis and pulmonary embolism in cancer patients. | Outpatient treatment of deep vein thrombosis (DVT) has become a common practice in uncomplicated patients. Few data are still present in patients with comorbidity (such as cancer) or concomitant symptomatic pulmonary embolism. Cancer patients with DVT are often excluded from home treatment because they have a higher ri... |
29,407 | Achilles tendon rupture and tendinopathy: management of complications. | Ailments of the Achilles tendon are on the increase and present in athletic and sedentary patients. The management of tendinopathy and rupture is not codified; Achilles tendon rupture and tendinopathy can be managed conservatively or surgically. Tackling the complications that arise from the management of these conditi... |
29,408 | Oral anticoagulation strategies after a first idiopathic venous thromboembolic event. | The optimal duration and intensity of warfarin therapy after a first idiopathic venous thromboembolic event are uncertain. We used decision analysis to evaluate clinical and economic outcomes of different anticoagulation strategies with warfarin.</AbstractText>We built a Markov model to assess 6 strategies to treat 40-... |
29,409 | Integrating the theories of Darwin and Bernoulli: maladaptive baroreceptor network dysfunction may explain the pathogenesis of aortic aneurysms. | Current treatment options for aortic aneurysms are suboptimal and their pathogenic mechanisms remain unclear. We propose the existence of a coordinated multi-node baroreceptor network that measures pressures at all vascular bifurcations and enables system-wide hemodynamic coordination and vasomotor regulation, in accor... |
29,410 | Renal tumor with associated venous tumor thrombus prolapsing through tricuspid valve during diastole. | We describe the case of a 76-year-old man with a renal cell carcinoma thrombus extending into the right atrium, prolapsing across the tricuspid valve into the right ventricle during diastole, and producing sufficient portal venous pressure to result in intestinal venous thrombosis and necrosis of the upper gastrointest... |
29,411 | [Study on the significance and application of crossover analysis in assessing gene-environmental interaction]. | To examine the significance of crossover analysis in gene-environmental interaction studies.</AbstractText>Through elaboration of a case-control study on the increased risk of venous thrombosis in oral-conceptive users who were carriers of factor V Leiden mutation, core information from 2 x 4 crossover table were analy... |
29,412 | The role of D-dimer and residual venous obstruction in recurrence of venous thromboembolism after anticoagulation withdrawal in cancer patients. | We assessed the predictive value of D-dimer (D-d) and residual venous obstruction (RVO), alone or in combination, for recurrent venous thromboembolism (VTE) over a 2-year follow-up in a cohort of 88 cancer patients after oral anticoagulant therapy (OAT) withdrawal following a first episode of proximal deep vein thrombo... |
29,413 | Implementing guidelines for venous thromboembolism prophylaxis in a large Italian teaching hospital: lights and shadows. | Venous thromboembolism (VTE) remains a serious complication in hospitalized patients, in spite of several published guidelines (GL) on its prevention. The objective of this study (part of the TRiPSS-2 project) was to evaluate the impact of a locally adapted GL, supported by a multifaceted implementation strategy, in im... |
29,414 | Treatment of superficial vein thrombosis to prevent deep vein thrombosis and pulmonary embolism: a systematic review. | The aim of this systematic review was to summarize the evidence from randomized controlled trials (RCT) concerning the efficacy and safety of medical or surgical treatments of superficial vein thrombosis (SVT) for the prevention of deep venous thrombosis (DVT) and pulmonary embolism (PE).</AbstractText>A systematic sea... |
29,415 | [Selective thrombolytic therapy for deep venous thrombosis by using a small caliber catheter passed through a temporary vena cava filter]. | To evaluate the feasibility of selective thrombolytic therapy for deep venous thrombosis (DVT)by using a small caliber catheter passed through a temporary vena cava filter.</AbstractText>During a 3-year period, 14 consecutive symptomatic patients (7 men, 7 women, age range, 35-80 years; mean, 62 years) were referred fo... |
29,416 | Is long-term low-molecular-weight heparin acceptable to palliative care patients in the treatment of cancer related venous thromboembolism? A qualitative study. | Venous thromboembolism (VTE) is common in patients with terminal cancer. Current treatment practice with warfarin has a high incidence of complications, including bleeding, poor control and recurrent VTE. Long-term low-molecular-weight heparin (LMWH) therapy is safer and more efficacious in this patient group, but ther... |
29,417 | Endoluminal recanalization in a patient with phlegmasia cerulea dolens using a multimodality approach-a case report. | Phlegmasia cerulea dolens is a limb-threatening form of deep venous thrombosis and should be treated aggressively. The authors report a patient who presented with iliocaval and femoral deep venous thrombosis and posed an additional therapeutic challenge based on a recent history of heparin-induced thrombocytopenia. Cat... |
29,418 | Thrombophilia screening in pregnancy. | Thromboembolism in pregnancy is a major contributor to pregnancy morbidity and mortality with potentially serious adverse effects for both mother and fetus. The purposes of this article are to explore the impact of heritable and acquired thrombophilias on pregnancy and to determine the appropriateness of screening for ... |
29,419 | Transjugular intrahepatic portosystemic shunt. | The transjugular intrahepatic portosystemic shunt (TIPS) is an interventional treatment resulting in decompression of the portal system by creation of a side-to-side portosystemic anastomosis. Since its introduction 16 years ago, more than 1,000 publications have appeared demonstrating broad acceptance and increasing c... |
29,420 | Steroid sparing in renal transplantation with tacrolimus and mycophenolate mofetil: three-year results. | Although renal transplantation with a 7-day steroid-sparing regimen, tacrolimus and mycophenolate, is associated with good short-term outcomes, late allograft dysfunction and failure remain concerns. In this study 101 consecutive patients underwent renal transplantation using this immunosuppressive regimen. In addition... |
29,421 | Long-term results of tacrolimus therapy for renal transplantation in patients with diabetic nephropathy in Japan. | In Japan, the number of kidney transplants for the patients with diabetic nephropathy is limited because of an extreme organ shortage and poor patient and graft survival rates. We analyzed the 5-year outcomes in kidney transplant recipients treated with tacrolimus with (group 1; n = 53) and without a diagnosis of diabe... |
29,422 | Efficacy and tolerability of a pasteurised human fibrinogen concentrate in patients with congenital fibrinogen deficiency. | The efficacy and tolerability of a pasteurised human fibrinogen concentrate were assessed in an open, multi-centre, non-controlled retrospective study in patients with congenital fibrinogen deficiency. Haemostatic efficacy was assessed by laboratory investigation and clinical observation. The study included 12 patients... |
29,423 | Prophylaxis for deep venous thrombosis in craniotomy patients: a decision analysis. | We sought to determine the most efficient perioperative prophylactic strategy for deep venous thrombosis (DVT) in craniotomy patients by use of a decision analysis model.</AbstractText>We conducted a structured review of the relevant literature and compiled the reported incidences of DVT, pulmonary embolism, and postop... |
29,424 | [Pregnancy-associated venous thrombosis in women with hereditary heterozygous factor V Leiden and/or factor II gene mutations]. | The risk of venous thromboembolism (VTE) in pregnant women with heterozygous factor V Leiden and/or heterozygous factor II 20210A gene mutations is poorly documented, and the need for prophylaxis is therefore controversial. We retrospectively studied 208 women with hereditary thrombophilia (heterozygous FV Leiden and/o... |
29,425 | Quantification of changes in electroencephalographic power spectra in a patient with Budd-Chiari-syndrome after implantation of a transjugular intrahepatic portosystemic stent shunt (TIPSS). | We examined a 41-year-old female with a subacute Budd-Chiari Syndrome (BCS) before and after implantation of a transjugular intrahepatic portosystemic stent shunt (TIPSS) by means of digital electroencephalography (EEG). After TIPSS implantation hepatic decompression had been achieved and the liver function as well as ... |
29,426 | [Delivery of a healthy child from pregnancy after IVF complicated hyperstimulation syndrome, phlebothrombosis and resection of uterine horn. Case report]. | To evaluate the negative effect of uterine horn resection for heterotopic pregnancy in the uterine horn in the first trimester on the course of pregnancy and labor. To point out the increased incidence of other complications in pregnancy after IVF+ET (ovarian hyperstimulation syndrome, phlebothrombosis of the pelvic ve... |
29,427 | [The frequency of venous thromboembolism in women with Leiden mutation in association with pregnancy and puerperium]. | The assessment of the frequency of venous thromboembolism (VTE) in women with F V Leiden in association with pregnancy and puerperium and according these results and available data to formulate the principles of thromboprophylaxis.</AbstractText>Retrospective case control study.</AbstractText>The assessment of frequenc... |
29,428 | An indium:calcium phosphate colloid that specifically targets fibrin. | The ability of indium to target fibrin in vitro was evaluated. The radionuclide (114m)Indium (114mIn) was prepared as a soluble and colloidal (In:In) form, as well as, a mixed indium:calcium phosphate (In:CaP) colloid. Soluble 114mIn was prepared by maintaining acid pH (50 mM HCl). Colloidal 114mIn (In:In) was prepared... |
29,429 | Analysis of a potential trigger of an acute illness. | Sometimes certain short-term risk exposures are postulated to act as a trigger for the onset of a specific acute illness. When the incidence of the illness is low it is desirable to investigate this possible association using only data on cases detected during a specific observation period. Here we propose an analysis ... |
29,430 | The Belgian Improvement Study on Oral Anticoagulation Therapy: a randomized clinical trial. | In Belgium, general practitioners (GPs) mainly manage oral anticoagulation therapy. To improve the quality of oral anticoagulation management by GPs and to compare different models and interventions, a randomized clinical trial was performed.</AbstractText>Stratified randomization divided 66 GP-practices into four grou... |
29,431 | A novel mouse model of autologous venous graft intimal hyperplasia. | To investigate the molecular mechanism of autologous venous graft intimal hyperplasia, a mouse model is needed. Currently only vein to carotid artery mouse models are available and are hampered by a high thrombosis rate. We hypothesized that operating on the aorta would lead to intimal hyperplasia with decreased risk o... |
29,432 | Reduced efficacy of clinical probability score and D-dimer assay in elderly subjects suspected of having deep vein thrombosis. | The combined strategy of a pretest clinical probability (PCP) score and D-dimer has shown to be of value in the diagnosis of deep vein thrombosis (DVT). As D-dimer concentrations increase with age, the effect of age on the usefulness of this strategy was retrospectively investigated in outpatients suspected of having D... |
29,433 | Sonographic evaluation of upper extremity deep venous thrombosis. | The purpose of this presentation is to review the techniques of performing an upper extremity Doppler examination, in addition to illustrating the sonographic appearances of acute and chronic upper extremity deep venous thrombosis (UEDVT).</AbstractText>The risk factors and complications of UEDVT are discussed, and the... |
29,434 | [Paradoxical brain embolism with a floating deep venous thrombus detected by sonography of lower extremities]. | A 68-year-old woman was admitted to our hospital due to brain embolism in the right middle cerebral artery. Patent foramen ovale was detected by transesophageal echocardiogram. The sonogram of the legs revealed a floating thrombus originating from the left posterior tibial vein and extended to the superficial femoral v... |
29,435 | An unusual presentation of metastatic testicular tumour. | We report a unique case of metastatic malignant teratoma from an undescended testis which presented with acute pulmonary embolism. After chemotherapy, the undescended right testicle was resected along with a cord of non- obstructing inferior venal caval tumour which extended into the right atrium with tumour floating f... |
29,436 | Resistance to activated protein C caused by factor V Leiden mutation and orthotopic liver transplantation. | Factor V (FV)-dependent resistance to activated protein C (APCR) is most likely caused by a point mutation in the FV gene, the so-called FV Leiden mutation (FV:Q506), which is a common risk factor predisposing to venous thromboembolism. Little is known about the role of FV:Q506 in recipients of human liver grafts and t... |
29,437 | The utility of TIPS in the management of Budd-Chiari syndrome. | Budd-Chiari syndrome (BCS) is a rare condition associated with hepatic venous outflow obstruction classically treated with portosystemic shunts or liver transplantation. Recent reports indicate promising results with the use of transjugular intrahepatic portosystemic shunts (TIPS) in the treatment of these patients.</A... |
29,438 | Resident work hour limits and patient safety. | This study evaluates the effect of resident physician work hour limits on surgical patient safety.</AbstractText>Resident work hour limits have been enforced in New York State since 1998 and nationwide from 2003. A primary assumption of these limits is that these changes will improve patient safety. We examined effects... |
29,439 | A nurse-led ambulatory care pathway for patients with deep venous thrombosis in an acute teaching hospital. | This article describes the management of deep vein thrombosis (DVT) using an ambulatory nurse-led pathway and the compression technique using duplex ultrasound. This pathway permits the management of the "walking wounded" as well as other patients at varying risks of having DVT and in so doing has changed the approach ... |
29,440 | Prospective evaluation of health-related quality of life in patients with deep venous thrombosis. | To our knowledge, the burden of deep venous thrombosis from the patient's perspective has not been quantified. We evaluated health-related quality of life (QOL) after deep vein thrombosis and compared results with general population norms.</AbstractText>This was a multicenter prospective cohort study of 359 consecutive... |
29,441 | Perception, assessment, treatment, and management of pain in the elderly. | Twenty to 50% of community elderly suffer from pain. Up to 80% of the institutionalized elderly report at least one pain problem. Multiple pain etiologies that occur in elderly patients may be the occurrence of multiple chronic diseases: osteoarthritis, RA, cancer, DJD, bone/joint disorders, osteoporosis, surgical pain... |
29,442 | Retrievable vena cava filters in trauma patients for high-risk prophylaxis and prevention of pulmonary embolism. | Venous thromboembolic (VTE) disease remains a significant cause of morbidity for trauma patients because many patients have injuries that may preclude effective VTE prevention and treatment. Retrievable vena cava filters may prove beneficial in this subset of trauma patients.</AbstractText>Trauma patients at risk for V... |
29,443 | Portal vein thrombosis after intraportal hepatocytes transplantation in a liver transplant recipient. | Hepatocytes transplantation is viewed as a possible alternative or as a bridge therapy to liver transplantation for patients affected by acute or chronic liver disorders. Very few data regarding complications of hepatocytes transplantation is available from the literature. Herein we report for the first time a case of ... |
29,444 | A single solution for multiple organ procurement and preservation. | Two or three different solutions may be used to preserve thoracic and abdominal organs during a single procurement. The aim of this prospective, multi-center, noncomparative study was to evaluate the safety and efficacy of Celsior (study solution, solution S) as a flushing and cold storage solution for both thoracic an... |
29,445 | Ultrasound-guided fine needle aspiration biopsy in differential diagnosis of portal vein tumor thrombosis. | Portal vein tumor thrombosis (PVTT) is a serious complication and a major metastatic way of hepatocellular carcinoma(HCC). But portal vein benign thrombosis(PVBT) always appears in patients with hepatocirrhosis, and PVTT should be differentiated from PVBT. The aim of this study was to probe the value of ultrasound-guid... |
29,446 | Performance of the automated and rapid STA Liatest D-dimer on the STA-R analyzer. | The aim of the present study was to investigate the accuracy indices of the new automated and rapid microlatex D-dimer assay, STA Liatest D-Di, on the STA-R analyzer and to compare it with established D-dimer assays.</AbstractText>D-dimer testing has been performed in 103 consecutive outpatients with suspected deep ven... |
29,447 | Argatroban anticoagulation in patients with a history of heparin-induced thrombocytopenia. | Heparin therapy is not recommended for patients with a history of heparin-induced thrombocytopenia (HIT), except in specialized situations, because this treatment can lead to severe reactions including thrombocytopenia and thrombosis. However, the optimal management of patients with a history of HIT requiring acute ant... |
29,448 | Upper extremity deep vein thrombosis. | A case of deep vein thrombosis of axillary vein (Paget-Schroetter syndrome) is described in an 18 years old male. Patient presented via emergency with a one week history of pain and swelling of arm. Duplex imaging showed deep vein thrombosis of third part of left axillary vein and venae comitantes of brachial artery. P... |
29,449 | Frequency of postoperative deep vein thrombosis in high-risk surgical patients. | To find the frequency of postoperative deep vein thrombosis (DVT) in high-risk surgical patients.</AbstractText>Cohort study.</AbstractText>The surgical department of the Combined Military Hospital, Rawalpindi from October 1997 to January 2000.</AbstractText>Patients of both genders were chosen from all the major branc... |
29,450 | Diagnostic yield of color Doppler ultrasonography in deep vein thrombosis. | To see the diagnostic yield of color Doppler ultrasonography in patients who presented with clinical symptoms and signs of acute deep vein thrombosis of lower limb.</AbstractText>Descriptive study.</AbstractText>The study was carried out in Bolan Medical Complex Hospital, Quetta from January 2002 to December 2002.</Abs... |
29,451 | Pylephlebitis due to perforated diverticulitis. | Pylephlebitis or septic thrombophlebitis of the portal vein is an uncommon and frequently fatal complication of diverticulitis. We describe a case report of a patient with pylephlebitis due to a perforation of the sigmoid. The patient was successfully treated with broad spectrum antibiotics and a Hartmann procedure. |
29,452 | Brachial artery pseudoaneurysm: a rare complication after haemodialysis therapy. | Haemodialysis patients carry a high risk of pseudoaneurysm due to inadvertent puncture of the brachial artery during venous cannulation for haemodialysis. Signs and symptoms are pulsatile mass and a systolic murmur. Complications are rupture, infection, haemorrhage, distal arterial insufficiency, venous thrombosis and ... |
29,453 | Doppler ultrasonography in a young patient with penile Mondor's disease. | Mondor reported the first superficial venous thrombosis on the chest wall in 1939. This condition is usually a benign and self-limited process, requiring only symptomatic treatment. Mondor's disease of the penis is an uncommon condition, which usually involves the superficial dorsal veins, it was first described by Bra... |
29,454 | Prolonged low dose IL-2 and thalidomide in progressive metastatic renal cell carcinoma with concurrent radiotherapy to bone and/or soft tissue metastasis: a phase II study. | Metastatic renal cell cancer is one of the immuno-sensitive tumors. Apart from the immuno-modulating agents IFNalpha and IL-2, thalidomide has been reported to be effective in this type of cancer. However, bone metastases and bulky metastases, show limited response to immunotherapy, are often site of recurrent disease ... |
29,455 | [Combined central retinal vein and artery occlusion after retrobulbar anesthesia--report of two cases]. | Two cases of combined central retinal artery and vein occlusion after intraocular surgery are described. Both patients were submitted to peribulbar anesthesia. Due to the painful sensation and ocular mobility retrobulbar anesthesia was necessary. At the end of the surgery both patients received a subconjunctival inject... |
29,456 | Efficacy of computer-aided dosing of warfarin among patients in a rehabilitation hospital. | To determine whether computer-aided dosing of warfarin is superior to physician dosing to maintain a patient in a rehabilitation hospital within a target international normalized ratio goal.</AbstractText>Randomized, double-blinded, clinical trial in an inpatient rehabilitation hospital. A total of 30 consecutive patie... |
29,457 | Corynebacterium diphtheriae endocarditis--surgery for some but not all!<Pagination><StartPage>119</StartPage><EndPage>126</EndPage><MedlinePgn>119-26</MedlinePgn></Pagination><Abstract><AbstractText>Corynebacterium diphtheriae endocarditis was thought to be a rare disease. We reviewed our experience in four cases of th... | Corynebacterium diphtheriae endocarditis was thought to be a rare disease. We reviewed our experience in four cases of this disease treated over a period of 10 years. Seventy cases reported in literature were reviewed. The outcome is good if cases are carefully selected for medical or surgical treatment. We conclude th... |
29,458 | Pharmacokinetics of ximelagatran and relationship to clinical response in acute deep vein thrombosis. | Our objective was to characterize the pharmacokinetics of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, and the relationship between melagatran exposure and clinical outcome in patients with acute deep vein thrombosis.</AbstractText>A population pharmacokinetic analysis was performed o... |
29,459 | Spinal epidural abscess-from onset to rehabilitation: case study. | Spinal epidural abscess (SEA) is a rare condition; consequently, the clinical significance of early diagnosis often is overlooked. The challenge with SEA is not its treatment, but achieving early diagnosis before neurological symptoms occur. Once neurological deficits are present, immediate treatment must be implemente... |
29,460 | [Epidemiology of venous thromboembolic disease]. | The wide variations in reported incidence and mortality rates reflect gaps in the epidemiology of venous thromboembolic disease (VTD), a clinical entity with two different manifestations--deep vein thrombosis and pulmonary embolism. We reviewed recent studies and data sources to find the most useful estimates of its ep... |
29,461 | Platelet microparticles and soluble P selectin in peripheral artery disease: relationship to extent of disease and platelet activation markers. | There is increased platelet activation in many cardiovascular diseases. This observation may explain the presence of increased levels of platelet microparticles (PMP) in these diseases. However, whether or not levels of PMPs inter-relate with other markers of platelet activation, such as soluble P-selectin, or with dis... |
29,462 | [Deep venous thrombosis and pulmonary embolism. Prophylaxis and therapy]. | Venous thromboembolism is a common cause of morbidity and mortality with an estimated annual incidence of 1:1,000. Several patient groups at risk can be differentiated, according to the presence of endogenous factors (such as hereditary thrombophilic disorders), but much more by exogenous factors (underlying disease). ... |
29,463 | [Direct inhibition of thrombin. A new strategy for the treatment of atrial fibrillation and acute coronary syndrome?]. | Direct inhibition of thrombin is a promising new strategy for the treatment of cardiovascular disease and thrombosis. Three intravenous (lepirudin, bivalirudin and argatroban) and one oral direct thrombin inhibitor (ximelagatran) are currently available and approved for some clinical indications in the treatment of car... |
29,464 | [Early thrombosis of radiocephalic fistula in patients on chronic hemodialysis (results of Kaunas University of Medicine Hospital 2000-2003)]. | In 2000-2003 surgeons performed 616 surgeries on arterio-venous access formation, more than 30% of them were radiocephalic. In 36.9% of cases of radiocephalic fistula early thrombotic complications developed (during the first month after operation) and a new access creation was needed. Various factors that indicate ear... |
29,465 | Live three-dimensional transthoracic echocardiographic assessment of thrombus in the innominate veins and superior vena cava utilizing right parasternal and supraclavicular approaches. | We report the usefulness of right parasternal and supraclavicular live three-dimensional transthoracic echocardiography in the delineation and follow-up of a thrombus involving a catheter placed in superior vena cava for dialysis in an adult patient with chronic renal disease. |
29,466 | [Value of ultrasound and doppler sonography in chronic hepatitis and liver cirrhosis]. | Ultrasound is unquestionably of great importance in the diagnosis of liver diseases due to the technical improvements of the last years. Indications for an ultrasound examination are the primary diagnosis of chronic liver disease and the screening for hepatocellular carcinoma. Apart from the diagnosis of portal hyperte... |
29,467 | Prevalence of factor V Leiden and prothrombin G20210A gene mutation. | To determine the prevalence of factor V Leiden (FVL) and prothrombin gene (PG) 20210A mutations in patients who attended the outpatient clinic and do not have a family history of thrombosis.</AbstractText>We researched FVL and PG20210A mutations in 151 outpatients (92 males and 59 females) who attended the Pediatrics P... |
29,468 | Impaired washout--embolism and ischemic stroke: further examples and proof of concept. | We previously posited that impaired washout of emboli was an important mechanism of brain infarction in patients with cerebral hypoperfusion. Hyperviscosity and hypoperfusion enhance thrombus formation promoting embolization of fresh thrombi. Hypoperfusion also reduces dissolution of emboli due to reduced flow velocity... |
29,469 | Thrombophilia, clinical factors, and recurrent venous thrombotic events. | Data on the recurrence rate of venous thrombotic events and the effect of several risk factors, including thrombophilia, remain controversial. The potential benefit of screening for thrombophilia with respect to prophylactic strategies and duration of anticoagulant treatment is not yet known.</AbstractText>To estimate ... |
29,470 | Therapeutic advances in interventional neurology. | Rapid advances in the field of interventional neurology and the development of minimally invasive techniques have resulted in a great expansion of potential therapeutic applications. We discuss therapeutic interventional neurology as applied in clinical practice in one of the two possible ways: 1) embolization leading ... |
29,471 | Lemierre's syndrome: Porphyromonas asaccharolytica as a putative pathogen. | A case of Lemierre's syndrome is reported in which metastatic abscesses resulted from septic thrombophlebitis of the internal jugular vein secondary to bacterial pharyngitis. A 32-year-old male suffering from a painful left-sided neck mass, sore throat, and fever was admitted to our hospital. Computed tomography reveal... |
29,472 | Extension of intracranial thrombosis after unilateral dissection of the internal jugular vein. | Resection of the internal jugular vein can be necessary in cases of radical neck dissection or even in cases involving benign neoplasms such as glomus tumors. According to the triad described by Virchow (ie, stasis of blood flow, damage to the endothelium, and changes in hemostasis), the development of a thrombosis in ... |
29,473 | Venous thromboembolism: regional differences in the nationwide inpatient sample, 1993 to 2000. | Venous thromboembolism (VTE) is a costly complication of hospitalization. The sequelae make it a concern for public health planners. The Nationwide Inpatient Sample (NIS) contains data for hospital discharges in the United States. These data were reviewed to determine their suitability for health policy planning. Inter... |
29,474 | 3. Sudden death due to pulmonary thromboembolism after car driving: a case report. | An autopsy case of sudden death due to pulmonary thromboembolism after a car trip is reported. A 56-year-old Japanese man with hypertension and atrial fibrillation suddenly died immediately after having driven for two and a half hours. At autopsy, the pulmonary arteries were found to be filled with dark-red, coiling th... |
29,475 | [Phlegmasia caerulea dolens: therapeutic considerations]. | Phlegmasia caerulea dolens is a rare complication of a deep venous thrombosis and is the result of a massive occlusion of all venous outflow of the extremity. Diagnosis must be made early in the course of the process for treatment effectiveness although it can only produce modest results. The authors analyse retrospect... |
29,476 | [Cardiac pseudotumor revealing Behçet's disease]. | Cardiac thrombosis is a rare complication of Behçet's disease (BD), which may present as a cardiac tumor. Its discovery precedes, in half of the cases, the diagnosis of BD. The high mortality may be associated to postsurgical complications and/or an associated involvement of pulmonary arteries.</AbstractText>We pr... |
29,477 | Site and clinical outcome of deep vein thrombosis of the lower limbs: an epidemiological study. | Clinical outcomes of patients diagnosed with venous thromboembolic disease (VTED) have rarely been assessed on large series of patients from single institutions. This was work based on our practice to routinely screen all suspected pulmonary embolism (PE) and deep venous thrombosis (DVT) patients with bilateral proxima... |
29,478 | Enoxaparin: a review of its use as thromboprophylaxis in acutely ill, nonsurgical patients. | Enoxaparin (Clexane), Lovenox) is a low molecular weight heparin (LMWH) that has been widely used in the prevention of venous thromboembolism (VTE) in surgical patients. More recently, with the recognition of the high incidence of VTE in acutely ill medical (nonsurgical) patients, enoxaparin has been evaluated for thro... |
29,479 | Traumatic aortic transection. | Traumatic aortic transection is an uncommon but often fatal injury. It is typically a high energy injury and may occur in the multiply injured patient. This injury is often missed. There is evidence that airbags and seat belts protect against these injuries. We present the case of a patient who survived. |
29,480 | Hemodynamic and metabolic changes in a patient with cerebral venous sinus thrombosis: evaluation using O-15 positron emission tomography. | The cerebral hemodynamics and oxygen metabolism before and after the recanalization of the occluded sinus were evaluated using O-15 positron emission tomography (PET) scanning in a 21-year-old woman with superior sagittal sinus thrombosis. During the initial presentation, there was increased regional cerebral blood vol... |
29,481 | Selective neck dissection: CT and MR imaging findings. | Selective neck dissection (SND) has become a common surgical procedure for selectively treating known or potential metastatic nodal disease from head and neck cancer while preserving functional structures. The purpose of this article is to describe the expected CT and MR findings after SND.</AbstractText>CT (26/27) or ... |
29,482 | Management problems of spontaneous ICH. | The management of spontaneous intracerebral haemorrhage (ICH) can be challenging for hospital doctors. Although the management of ICH is covered in stroke guidelines, many difficult clinical questions remain. In this article the authors suggest approaches to ten common and difficult questions. |
29,483 | Heparin-induced skin lesions and other unusual sequelae of the heparin-induced thrombocytopenia syndrome: a nested cohort study. | Heparin-induced thrombocytopenia (HIT) is caused by platelet-activating, heparin-dependent IgG antibodies (HIT-IgG). Although HIT is known to predispose the patient to thrombosis, the relationship between the formation of HIT-IgG and various other unusual clinical sequelae putatively linked with the HIT syndrome, such ... |
29,484 | Bed rest or ambulation in the initial treatment of patients with acute deep vein thrombosis or pulmonary embolism: findings from the RIETE registry. | Traditionally, many patients with acute deep vein thrombosis (DVT) are treated not only by anticoagulation therapy but additionally by strict bed rest, which is aimed at reducing the risk of pulmonary embolism (PE) events. However, this risk has not been subjected to empirical verification.</AbstractText>The Registro I... |
29,485 | Contrast-enhanced MR angiography for evaluation of vascular complications of the pancreatic transplant. | Vascular complications are a common cause of postoperative dysfunction in a pancreatic transplant. Coronal three-dimensional (3D) contrast material-enhanced magnetic resonance (MR) angiography performed with high spatial and temporal resolution is a safe and effective method of assessing these vascular complications. A... |
29,486 | Heparin-induced thrombocytopenia in a renal transplant recipient. | Heparin-induced thrombocytopenia (HIT) type II is an immunologically mediated reduction in platelets that increases the risk of arterial or venous thrombosis. It has been reported in up to 5% of patients receiving unfractionated heparin. Unlike other thrombocytopenic coagulopathies, HIT is associated with a high risk o... |
29,487 | Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring. | A series of novel 2,7-disubstituted tetrahydroisoquinoline derivatives were designed and synthesized. Among these derivatives, compounds 1 and 2 exhibited potent inhibitory activity against factor Xa (FXa) and good selectivity with respect to other serine proteases (thrombin, plasmin, and trypsin). In addition, compoun... |
29,488 | Reviparin sodium clivarine: a review of its therapeutic use. | Reviparin sodium (clivarine) is a second generation LMWH, developed with the aim of maximising the antithrombotic action while minimising the risk of haemorrhage. Clivarine has been extensively studied in acute coronary syndrome. Various clinical studies in unstable angina and acute coronary syndrome have proved that c... |
29,489 | [Modern aspects of varicose vein surgery]. | In Germany almost every third adult suffers from varicose veins requiring treatment. Conventional varicose vein surgery by high ligation and stripping is widely accepted as standard therapy for saphenous vein insufficiency, although associated with a high frequency of recurrent varicosities. Innovative endovascular pro... |
29,490 | Diagnostic management of pulmonary embolism using clinical assessment, plasma D-dimer assay, complete lower limb venous ultrasound and helical computed tomography of pulmonary arteries. A multicentre clinical outcome study. | The objective of the study was to assess the clinical validity of a non-invasive diagnostic strategy for acute pulmonary embolism using clinical assessment combined with both ELISA D-dimer and complete lower limb ultrasound (US) examination of proximal and distal veins, before single-detector helical computed tomograph... |
29,491 | Prevalence of venous thromboembolism at a teaching hospital in Okinawa, Japan. | Limited data suggest that Asian Americans may have a lower risk of venous thromboembolism (VTE) than Caucasians. However, the actual prevalence of VTE among Asians remains controversial, and has not been described in Japan. We studied all 131,060 patients hospitalized at a single medical centre in Japan (January 1987 -... |
29,492 | Patients with unstable control have a poorer dietary intake of vitamin K compared to patients with stable control of anticoagulation. | Evidence suggests that alterations in the dietary intake of vitamin K can affect anticoagulation response to warfarin. It is possible that a low and erratic intake of dietary vitamin K is at least partly responsible for the variable response to warfarin in patients with unstable control of anticoagulation. Twenty-six p... |
29,493 | Fatal vascular outcomes following major orthopedic surgery. | Major orthopedic surgery is known to be associated with potentially serious arterial and venous vascular complications, although uncertainty exists about current event rates. Using electronic databases and investigator contact, we identified randomized and cohort studies reporting overall mortality and fatal vascular e... |
29,494 | Elevated factor VIII is a risk factor for idiopathic venous thromboembolism in Canada - is it necessary to define a new upper reference range for factor VIII? | Previous studies suggest elevated factor VIII is a common, independent risk factor for venous thromboembolism (VTE); however, these studies included secondary and idiopathic VTE. We sought to explore the association between elevated factor VIII and VTE in Canadian patients with idiopathic thrombosis, and confirm the cu... |
29,495 | The role of neovascularisation in the resolution of venous thrombus. | Deep vein thrombosis (DVT) can give rise to chronic debilitating complications, which are expensive to treat. Anticoagulation, the standard therapy for DVT, prevents propagation, but does not remove the existing thrombus, which undergoes slow natural resolution. Alternative forms of treatment that accelerate resolution... |
29,496 | Low-dose warfarin for prevention of symptomatic thromboembolism after orthopedic surgery. | Warfarin dosing with a target international normalized ratio (INR) range of 1.5-2.5 has not been reported as adequate for venous thromboembolism (VTE) prophylaxis after total knee (TKR) and total hip replacement (THR) surgery.</AbstractText>To evaluate the rate of symptomatic VTE after TKR and THR surgery using a low-d... |
29,497 | Extensive prolongation of aPTT with argatroban in an elderly patient with improving renal function, normal hepatic enzymes, and metastatic lung cancer. | To report a case of an elderly male with improving renal function and normal hepatic function who sustained an elevated activated partial thromboplastin time (aPTT) after an infusion of argatroban was discontinued.</AbstractText>A 77-year-old white male with a history of heparin-induced thrombocytopenia (HIT) and metas... |
29,498 | [Venosus thromboembolism in pregnancy--case report]. | Venosus thromboembolic disease is an important problem in pregnant women. The overall risk of venosus thromboembolism in pregnancy is 6-times greater then in non pregnant women. In the article we present a case of a pregnant woman with venosus thromboembolism. The analysis of the pregnancy and mode of delivery, develop... |
29,499 | [Prophylactic role of the specifics and dynamics of health-related behaviors in patients with lower limb arteriosclerosis]. | The article presents longitudinal research into peculiarity and dynamics of health behaviours in patients suffering from atheromatosis of he lower limb arteries. The aim of the research was to show how the onset of the disease influenced patients to change their health behaviours. The survey was conducted in 2002-2003 ... |
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