Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
29,600 | Short-term effects of estrogen, tamoxifen and raloxifene on hemostasis: a randomized-controlled study and review of the literature. | Estrogen therapy (ET), tamoxifen and raloxifene are associated with a two- to three-fold increased risk of venous thrombosis (VT); however, the mechanisms by which each drug increases venous thrombosis propensity are not fully understood. The objectives of this investigation were to compare the effects of these three t... |
29,601 | [2 patients with signs of venous thromboemolism: deviations from the guidelines]. | Deviations from the relevant guidelines occurred during the diagnosis of 2 patients with clinical signs of venous thromboembolism (VTE). In a 73-year-old man with bladder cancer and dyspnoea in whom pulmonary embolism was suspected, pulmonary angiography was not performed following a negative ventilation/perfusion scan... |
29,602 | Capability of multidetector CT to diagnose hepatocellular carcinoma-associated arterioportal shunt. | To investigate the capability of multidetector CT (MDCT) to diagnose HCC-associated arterioportal shunt (APS).</AbstractText>Two hundred and eighty-two patients with HCC received both thin-slice and enhancement MDCT scanning at early hepatic arterial phase, late hepatic arterial phase and portal venous phase, and digit... |
29,603 | A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project. | Homocysteine (Hcy) plasma level is an independent risk marker for venous thrombosis, myocardial infarction, stroke, congestive heart failure, osteoporotic fractures, and Alzheimer disease. Hcy levels are determined by the interaction of genetic and environmental factors. The genetic basis is still poorly understood, si... |
29,604 | Management of von Willebrand disease with factor VIII/von Willebrand factor concentrates: results from current studies and surveys. | Until the mid 1980s, cryoprecipitate had been the mainstay of treatment of patients with von Willebrand disease (VWD) who were unresponsive to desmopressin. The advent of virally inactivated factor VIII/von Willebrand factor (FVIII/VWF) concentrates, originally developed for the treatment of patients with hemophilia, p... |
29,605 | Antithrombotic effect of captopril and enalapril in old rats. | In the present study, we have shown considerably accelerated thrombosis in old rats in comparison with adult rats, which may be related to the impaired hemostatic balance in these animals. In old rats, captopril and enalapril caused a marked reduction of venous thrombus weight. The mechanism of antithrombotic action of... |
29,606 | Three-year evaluation of late breast reconstruction with a free transverse rectus abdominis musculocutaneous flap in a county hospital in Sweden: a retrospective study. | We present our three-year experience of late breast reconstruction with conventional free TRAM flaps in 16 consecutive patients in a Swedish county hospital. The breast reconstruction was done unilaterally in 14 and bilaterally in two, giving a total of 18 free TRAM flaps in 16 patients. Six patients developed anastomo... |
29,607 | Liver transplantation in recipients with portal vein thrombosis: experience of a single transplant center. | Although portal vein thrombosis (PVT) is no longer considered a contraindication for liver transplantation (OLT), it is still considered a high risk because of the complexity of the surgical procedure. The aim of this study was to evaluate the impact of PVT in the recipient during OLT on intra- and perioperative manage... |
29,608 | Liver transplantation using cavoportal transposition: an effective treatment in patients with complete splanchnic venous thrombosis. | Complete venous thrombosis of the splanchnic system remains a major challenge in liver transplantation surgery. Some of these patients have been treated successfully by multivisceral transplantation. Cavoportal transposition is another alternative to treat these patients. We reviewed our single-center experience with t... |
29,609 | Does pretransplant obesity affect the outcome in kidney transplant recipients? | The effect of obesity on renal transplant outcome remains unclear due to conflicting published studies. The purpose of this study was to assess whether obesity affects the outcome in renal transplant patients.</AbstractText>We retrospectively analyzed 33 obese (BMI >30; mean = 34.1 +/- 3.68; group I) and 35 nonobese... |
29,610 | [Surgical details and complications from retransplantation into the iliac fossa for third and fourth kidney transplants]. | To analyze the surgical aspects and complications from retransplantation into the iliac fossa for third and fourth kidney transplants.</AbstractText>Retrospective study of the 34 third and 5 fourth transplants performed in our department. We analyze patient's characteristics, surgical aspects and complications, and gra... |
29,611 | Deep venous thrombosis in elderly hospitalized patients: prevalence and clinical features.<Pagination><StartPage>42</StartPage><EndPage>45</EndPage><MedlinePgn>42-5</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND AND AIMS" NlmCategory="OBJECTIVE">It is not known whether old age influences the clinica... | It is not known whether old age influences the clinical outcome of deep venous thrombosis (DVT) in patients admitted to acute internal medicine wards. This study aimed at evaluating the effect of age on the prevalence and clinical features of DVT in patients admitted to acute medical wards in a general hospital.</Abstr... |
29,612 | Utility of contrast-enhanced 3D turbo-flash MR angiography in evaluating the intracranial venous system. | The objective of this study was to compare the effectiveness of contrast-enhanced 3D turbo-flash and 2D time-of-flight (TOF) magnetic resonance angiography (MRA) sequences in the visualization and evaluation of the intracranial venous system. A prospective study was carried out on 41 patients referred to our Magnetic R... |
29,613 | Erythrocyte adhesiveness/aggregation: a novel biomarker for the detection of low-grade internal inflammation in individuals with atherothrombotic risk factors and proven vascular disease. | We have introduced a concept of using the erythrocyte as a sensor for the detection of enhanced inflammation-sensitive protein concentrations. We presently evaluated the capability of this new biomarker to detect the presence of inflammation in individuals with a history of a vascular disease as opposed to individuals ... |
29,614 | Prevalent misconceptions about acute retinal vascular occlusive disorders. | Acute retinal vascular occlusive disorders collectively constitute one of the major causes of blindness or seriously impaired vision, and yet there is marked controversy on their pathogeneses, clinical features and particularly their management. This is because the subject is plagued by multiple misconceptions. These i... |
29,615 | Transjugular intrahepatic cavoportal shunt for Budd-Chiari syndrome. | Budd-Chiari syndrome (BCS) is characterized by obstruction of the hepatic venous outflow tract. Therapeutic options for BCS are limited. We report a case of a 21-year-old woman with protein S and C deficiency with gross ascites. Treatment with transjugular intrahepatic portosystemic shunt (TIPS) was attempted, which re... |
29,616 | Cerebral venous sinus thrombosis presenting as subdural haematoma. | The authors report a 39-year-old woman who presented with intermittent, excruciating nuchal and occipital headache. Magnetic resonance imaging and magnetic resonance angiography scans showed bilateral subdural haematomas with veno-occlusive disease of the superficial and deep venous systems. There were bridging collate... |
29,617 | [Surgical approach to retinal vein occlusion]. | Retinal vein occlusions are the second most common vision threatening retinal vascular disorders. Our therapeutic armamentarium for functional improvement was very limited in the past for all types of retinal vein occlusions (branch, central and hemi-central retinal vein occlusion). Also pathomechanism and risk factors... |
29,618 | Recombinant tissue plasminogen activator infusion for hemodialysis catheter clearance. | Hemodialysis (HD) catheter occlusion is a common cause of poor blood flow and inadequate dialysis. In order to address this problem in our pediatric dialysis unit, we elected to use short (2-h) infusions of low-dose recombinant tissue plasminogen activator (rtPA) for thrombolysis of occluded catheters. Catheters meetin... |
29,619 | [A case of pulmonary thromboembolism in active ulcerative colitis]. | Thromboembolic disease is a significant cause of morbidity and mortality in patients with inflammatory bowel disease. The reported incidence is 1-6%. The most common thromboembolic complications are deep venous thrombosis of legs and pulmonary thromboembolism. Cerebral thrombosis, portal vein thrombosis, retinal venous... |
29,620 | [Diagnosis and treatment of tentorial dural arteriovenous fistulae]. | Tentorial dural arteriovenous fistulae are uncommon but life-threatened lesions. We present our experience of 5 cases with tentorial dural arteriovenous fistulae, review the relevant literature and present the rationale of our current management strategy.</AbstractText>The data of five patients with tentorial DAVF trea... |
29,621 | Thrombomodulin gene polymorphisms or haplotypes as potential risk factors for venous thromboembolism: a population-based case-control study. | Dysfunction of the protein C anticoagulant system is associated with venous thromboembolism (VTE) and thrombomodulin (TM) is a critical cofactor within the protein C system. The aim of this study was to test the hypotheses that polymorphisms or haplotypes within the TM gene are common risk factors for VTE. We screened ... |
29,622 | Clinical outcome of patients with venous thromboembolism and recent major bleeding: findings from a prospective registry (RIETE). | Patients who have experienced a recent major bleeding episode are usually excluded from clinical studies of venous thromboembolism (VTE) treatment. Therefore, recommendations based on evidence from clinical trials may not be suitable for these patients. The Registro Informatizado de la Enfermedad TromboEmbolica (RIETE)... |
29,623 | The G20210A prothrombin-gene mutation and the plasminogen activator inhibitor (PAI-1) 5G/5G genotype are associated with early onset of severe preeclampsia. | Hereditary risk determinants of venous thrombosis have been reported to be associated with severe preeclampsia. So far there are no data to support whether these risk determinants are related to the time of onset of severe preeclampsia. We used a case-control design, studying 97 women with severe preeclampsia in previo... |
29,624 | The oral direct thrombin inhibitor, ximelagatran, an alternative for anticoagulant treatment during the puerperium and lactation. | To determine the excretion of the oral direct thrombin inhibitor (oral DTI), ximelagatran, and its active form, melagatran, in human milk, and to thus evaluate the potential exposure of breastfed infants to melagatran.</AbstractText>An open, single dose, single centre study.</AbstractText>Department of Antenatal Care, ... |
29,625 | Stroke and antiphospholipid syndrome: the treatment debate. | Antiphospholipid syndrome (APS) is one of the most frequent acquired thrombophilias. Thromboses can be at both the venous and arterial level, are usually recurrent and frequently affect cerebral circulation. Although it is difficult to predict which patients with antiphospholipid antibodies (aPL) will develop thrombosi... |
29,626 | Inflow stenosis in arteriovenous fistulas and grafts: a multicenter, prospective study. | Traditionally, arteriovenous hemodialysis access inflow stenosis has been reported to occur infrequently (0% to 4%). In contrast, recent reports have suggested a significantly higher incidence (14% to 42%). Interpretation of these studies has been complicated by the presence of one or more confounding factors such as r... |
29,627 | The artificial lung facility at Brown: more than a dozen years with Pierre Galletti. | Beginning in 1969, Pierre Galletti and his colleagues established a laboratory at Brown University, which, initially and for many years, was involved with artificial lungs. Various projects budded out of this, including the following: the establishment of standards for oxygenator performance, which anticipated Food and... |
29,628 | A phase II trial of docetaxel and vinorelbine in patients with hormone-refractory prostate cancer. | Recent studies of docetaxel have demonstrated improved survival over mitoxantrone and prednisone in patients with hormone-refractory prostate cancer (HRPC), supporting the study of novel docetaxel-containing regimens as primary therapy or following initial docetaxel-based therapy. To evaluate the combination of docetax... |
29,629 | Risk factors for mortality in patients with upper extremity and internal jugular deep venous thrombosis. | To elucidate the natural history of upper extremity deep venous thrombosis (UEDVT), we examined factors that may contribute to the high mortality associated with UEDVT.</AbstractText>Five hundred forty-six patients were diagnosed with acute internal jugular/subclavian/axillary deep venous thrombosis from January 1992 t... |
29,630 | Accuracy of ICD-9-CM codes for identifying cardiovascular and stroke risk factors. | We sought to determine which ICD-9-CM codes in Medicare Part A data identify cardiovascular and stroke risk factors.</AbstractText>This was a cross-sectional study comparing ICD-9-CM data to structured medical record review from 23,657 Medicare beneficiaries aged 20 to 105 years who had atrial fibrillation.</AbstractTe... |
29,631 | Brief communication: high incidence of venous thrombotic events among patients with Wegener granulomatosis: the Wegener's Clinical Occurrence of Thrombosis (WeCLOT) Study. | Venous thrombotic events (VTEs) have been observed in Wegener granulomatosis, but the incidence rate is not known.</AbstractText>To measure the incidence of VTEs in patients with Wegener granulomatosis.</AbstractText>Prospective, observational cohort study.</AbstractText>A multicenter, randomized, double-blind, placebo... |
29,632 | Infectious complications of central venous catheters increase the risk of catheter-related thrombosis in hematology patients: a prospective study. | We studied whether the risk of central venous catheter (CVC) -related thrombosis increased after an episode of CVC-related infection in patients undergoing intensive chemotherapy. Secondly, we determined whether thrombosis can be predicted or excluded by CVC lock fluid surveillance cultures.</AbstractText>In a prospect... |
29,633 | Surgical outcome following radical nephrectomy in cases with inferior vena cava tumour thrombus extension. | To report our experience with extensive surgery in patients with and without metastatic renal cell carcinoma and gross venous tumour thrombus.</AbstractText>Twenty-seven patients with unilateral renal cell carcinoma and tumour thrombus into the vena cava underwent radical nephrectomy and thrombectomy. Eight patients pr... |
29,634 | Budd-Chiari-like presentation of hepatic adenoma. | Hepatic adenoma is a benign tumor characterized by its hypervascularity. Hepatic adenoma tends to occur more frequently in women and is related to the use of contraceptive hormones, androgenic/anabolic steroids, pregnancy, glycogen storage diseases and hemochromatosis. Hepatic venous obstruction, or Budd-Chiari syndrom... |
29,635 | [Portal vein thrombosis associated with hepatic encephalopathy]. | A 54-year-old man who had been administered chlormadinone acetate 3 months after prostatectomy for prostate cancer, acutely developed disorientation and memory disturbance. Six days later, he experienced high grade fever and epigastralgia. He was suspected to have hepatic encephalopathy, because the Fischer ratio was l... |
29,636 | Radial optic neurotomy for ischaemic central vein occlusion. | <AbstractText Label="BACKGROUND/AIMS" NlmCategory="OBJECTIVE">Ischaemic central retinal vein occlusion (CRVO) accounts for 20-50% of all CRVO. No treatment has been proved to be effective. The efficacy of radial optic neurotomy (RON) was evaluated in eyes with ischaemic CRVO.</AbstractText>10 patients with ischaemic CR... |
29,637 | Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome. | A 3.5-year-old healthy boy with 4 days of fever was referred to the emergency department for respiratory distress. The physical examination was remarkable for stupor, tachycardia, tachypnea, and dyspnea. Initial blood tests showed pancytopenia. He rapidly developed torticollis. Computerized tomography of the neck revea... |
29,638 | Clinical inquiries. Does anticoagulation prevent thrombosis for persons with fractures distal to the hip? | Low-molecular-weight heparin (LMWH) prophylaxis significantly reduces the total incidence of deep venous thrombosis (DVT) for patients with lower-limb fractures managed with surgical fixation and cast immobilization (strength of recommendation [SOR]: A, based on multiple randomized controlled studies [RCTs]). Evidence ... |
29,639 | Use of the femoral vein ('groin injecting') by a sample of needle exchange clients in Bristol, UK. | BACKGROUND: Use of the femoral vein for intravenous access by injecting drug users (IDUs) (commonly called 'groin injecting') is a practice that is often observed but on which little is written in the literature. The purpose of this study was to describe self-reported data from a sample of groin injectors on the natura... |
29,640 | The poor outcome of the delayed diagnosis of acute spontaneous spinal epidural hematoma: two cases report. | We present two patients who had acute paraplegia with sensory loss due to spontaneous spinal epidural hematoma (SSEH). One had myocardial infraction and the other had deep vein thrombosis, and the former was treated with anticoagulants and the latter was treated with thrombolytic agent. We analyzed the neurological sta... |
29,641 | Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation. | Splanchnic vein thrombosis is a significant source of complications in candidates for liver transplantation. The aims of this study were: (a) to determine the prevalence of and risk factors for splanchnic vein thrombosis in cirrhotic patients awaiting transplantation and (b) to assess the usefulness of anticoagulation.... |
29,642 | Analysis of prothrombotic mutations and polymorphisms in children who developed thrombosis in the perioperative period of congenital cardiac surgery. | In this study, we investigated some of the prothrombothic mutations and polymorphisms in 15 children with congenital cardiac malformations who developed severe thrombosis in the perioperative period following surgical repair. The mutations and polymorphisms included in the study were Factor V Leiden, prothrombin G20210... |
29,643 | Post-transplant IVC occlusion and thrombosis treated with tPA, heparin, and sharp recanalization. | Complete inferior vena cava (IVC) thrombosis can be a lethal complication in a liver transplant recipient. The case of a 52-year-old liver transplant recipient, who developed complete IVC as well as left iliofemoral thrombosis, is reported. After treatment with combined tissue plasminogen activator (tPA) and heparin, t... |
29,644 | [An unusual foreign body in the upper gastrointestinal tract causing nonspecific abdominal pain]. | The risk of penetration of vena cava filters through the wall of the vena cava is estimated to be as high as 25%, although clinical symptoms are observed far less frequently in patients with this complication. Due to the close relationship between vena cava and duodenum, the latter can be injured by dislocated filters.... |
29,645 | [Hormone therapy and risk for venous thromboembolism in postmenopausal women]. | Oral estrogens are associated with a two-fold to three-fold increased risk of venous thromboembolism in postmenopausal women. Absolute excess risk is low but higher than for contraceptive pills. Biological data and observational studies suggest that transdermal estrogens are associated with a lower risk for venous thro... |
29,646 | [Evaluation of macula in patients with branch retinal vein occlusion using multifocal electroretinogram and optical coherence tomography]. | To evaluate the functions of the macular area in patients with branch retinal vein occlusion (BRVO) by using multifocal electroretinograms (mERG) and optical coherence tomography(OCT).</AbstractText>mERGs were recorded from 18 eyes of 18 patients with BRVO. An array of 103 hexagonal elements was displayed on a monitor.... |
29,647 | Genomic susceptibility-testing and pregnancy: something old, something new. | This essay explores how testing for common and complex or genomic, as opposed to genetic, susceptibility to deep vein thrombosis both challenges and consolidates old social discourses on genes, gender and pregnancy. The nexus between genetics and reproduction usually crystallizes in the moral dilemma of selective termi... |
29,648 | The relationship between postoperative complications and outcomes after hip fracture surgery. | We studied the prevalence of postoperative complications in a series of consecutive patients who received surgery for hip fractures in a major public hospital in Singapore. We also studied the predictors for the occurrence of complications and the impact of these complications on patient outcomes.</AbstractText>A retro... |
29,649 | FDG uptake in tumor thrombus in inferior vena cava from rectal cancer on positron emission tomography. | A 74-year-old woman with a history of rectal carcinoma underwent whole body combined positron emission tomography/computed tomography (PET/CT) scanning for staging. Diffuse intense FDG uptake was seen in the distended infrarenal inferior vena cava (IVC) extending to the bilateral common iliac and left external as well ... |
29,650 | FDG uptake in a catheter-related thrombus simulating relapse of lymphoma. | FDG-PET imaging was performed because of suspected recurrence of lymphoma of the chest. There was an area of increased activity posterior to the left sternoclavicular joint, suspected of being a relapse. Workup showed a thrombus at the tip of a central venous line corresponding to the FDG uptake. This is explained by t... |
29,651 | [Low molecular weight heparin in patients undergoing vascular surgery]. | Despite the fact that there are no approved indications by the French regulatory agency and despite the absence of recommendations, low molecular weight heparins (LMWH) are frequently used in vascular surgery, an area at both high risk of perioperative arterial and venous thrombosis as well as of bleeding. The aim of t... |
29,652 | Operative management of acetabular fractures. A review of 73 fractures. | Between June 1994 and December 2000, 80 displaced acetabular fractures were treated by open reduction and internal fixation, where possible by a single surgical approach. We report our results in 72 patients (73 fractures) who completed a minimum follow-up of 2 years. The average age of patients was 39.5 years (range 1... |
29,653 | [Markers of thrombophilia in patients with retinal vein thrombosis]. | Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis.</AbstractText>To study the presence of thrombophilia in patients with retinal vein thrombosis.</AbstractText>Prospective study of 55 patients aged... |
29,654 | [Bilateral central retinal vein occlusion associated with blood hyperviscosity syndrome--case report]. | The authors report the case of a 16-year-old male patient who presented with blurred vision and bilateral optic disc edema, then developing bilateral central retinal vein occlusion. On laboratory work-up, he was found to have multiple myeloma IgA along with hyperviscosity syndrome, which led to the ophthalmological fea... |
29,655 | Evaluation of the applicability, efficacy, and safety of a thromboembolic event prophylaxis guideline designed for quality improvement of the traumatically injured patient. | Thromboembolic events (TE) such as deep venous thrombosis (DVT) and pulmonary embolism (PE) are common after trauma. Our Trauma Practice Management Committee developed an evidence-based DVT/PE prophylaxis guideline using a modified Delphi approach to standardize care and reduce TE rates. Our objective was to evaluate t... |
29,656 | A randomized trial comparing 2 low-molecular-weight heparins for the outpatient treatment of deep vein thrombosis and pulmonary embolism. | Low-molecular-weight heparins (LMWHs) are now standard therapy for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). No published trials have compared LMWHs, and few studies have examined outpatient therapy for PE. Only tinzaparin sodium has demonstrated superiority to unfractionated heparin in a... |
29,657 | Significant reduction of the risk of venous thromboembolism in all long-term immobile patients a few months after the onset of immobility. | Prophylactic anticoagulation is a standard practice in patients with sudden lower limbs paralysis. Thromboprophylaxis is usually continued until the patient regains independent mobility. The duration of anticoagulation in long-term immobile patients is unknown. Spinal cord injury patients are the only population that w... |
29,658 | Thrombolytic therapies: the current state of affairs.<Pagination><StartPage>224</StartPage><EndPage>232</EndPage><MedlinePgn>224-32</MedlinePgn></Pagination><Abstract><AbstractText>Thrombotic occlusive diseases are manifested in several disorders that have significant morbidity and mortality, including acute myocardial... | Thrombotic occlusive diseases are manifested in several disorders that have significant morbidity and mortality, including acute myocardial infarction, pulmonary embolism, deep venous thrombosis, and cerebrovascular accidents. This review summarizes the recently published literature covering thrombolytic therapies in t... |
29,659 | Three-dimensional conformal radiotherapy for portal vein thrombosis of hepatocellular carcinoma. | Portal vein thrombosis (PVT) is a common complication in patients with advanced-stage hepatocellular carcinoma (HCC). The authors evaluated the impact of radiotherapy (RT) for PVT of HCC and analyzed the dose-response relation between RT and PVT.</AbstractText>Between March 1995 and December 2003, 59 patients diagnosed... |
29,660 | The first three years of the Swiss Neuropaediatric Stroke Registry (SNPSR): a population-based study of incidence, symptoms and risk factors. | We report the results of three years of the population-based, prospective Swiss NeuroPaediatric Stroke Registry (SNPSR) of children (up to 16 years) with childhood arterial ischaemic stroke (AIS1), neonatal stroke (AIS2), or symptomatic sinus venous thrombosis (SVT). Data on risk factors (RF), presentation, diagnostic ... |
29,661 | Diagnosis of antiphospholipid syndrome during the diagnostic workup of second-trimester fetal bradycardia. | Antiphospholipid syndrome (APS) is an autoimmune disorder associated with either arterial and/or venous thrombosis (1). Two cases of APS, which were diagnosed in the second trimester during the diagnostic workup of fetal bradycardia, are presented. |
29,662 | Clinicohematologic spectrum in patients with lupus anticoagulant. | A retrospective analysis of clinicohematologic parameters of 25 patients with lupus anticoagulant was carried out. The hematologic tests included dilute Russel viper venom test (dRVVT), kaolin clotting time (KCT), activated partial thromboplastin time, and prothrombin time. The diagnosis of lupus anticoagulants was bas... |
29,663 | Prevalence of thromboembolic disease including superior vena cava and brachiocephalic veins. | Thrombosis of the brachiocephalic veins or superior vena cava (SVC) is rare. This study was conducted to determine the prevalence and characteristics of thrombosis of brachiocephalic veins and SVC , and its association with symptomatic pulmonary embolism (PE). The prevalence of thrombosis involving the brachiocephalic ... |
29,664 | Association of anticardiolipin antibody and C677T in methylenetetrahydrofolate reductase mutation in women with recurrent spontaneous abortions: a new path to thrombophilia? | Recurrent spontaneous abortion (RSA) has been associated with venous thrombosis in the mother. Acquired and inherited thrombophilia factors are possible causes.</AbstractText>To evaluate the association between thrombogenic factors and recurrent spontaneous abortion.</AbstractText>Case-control study.</AbstractText>Cent... |
29,665 | Venous thrombosis prophylaxis for urological laparoscopy: fractionated heparin versus sequential compression devices. | Venous thromboembolism (VTE) is a significant postoperative complication. Common methods of VTE prophylaxis include subcutaneous fractionated heparin (FH) and lower extremity sequential compression devices (SCD). There is no conclusive evidence supporting 1 method compared to the other for urological laparoscopy. We ex... |
29,666 | Elevated levels of D-dimer and fragment 1+2 upon central venous catheter insertion and factor V Leiden predict subclavian vein thrombosis. | Subclavian vein thrombosis is a well-recognized complication following central venous catheter insertion. We studied whether the determination of D-dimer levels, fragment 1+2 levels and factor V Leiden can identify patients at high risk of developing subclavian vein thrombosis.</AbstractText>The presence of central ven... |
29,667 | [Symptomatic thrombosis in central venous catheter in oncology: a predictive score?]. | Central venous catheters are essential to management of cancer patients. Thrombotic complications are potentially severe, but it is difficult to prescribe systematically a prophylactic treatment. So it is necessary to identify the higher risk patients who need a prophylaxis.</AbstractText>To identify factors associated... |
29,668 | Antiphospholipid syndrome. | Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by a combination of arterial or venous thrombosis and recurrent fetal loss, accompanied by elevated titers of antiphospholipid antibodies (aPL). APS has been recognized as the leading cause of vascular thrombosis in children. The diagnostic... |
29,669 | Cost consequence analysis of fondaparinux versus enoxaparin in the prevention of venous thromboembolism after major orthopaedic surgery in Belgium. | Fondaparinux, a selective inhibitor of activated factor X, has been shown to reduce further the risk of venous thromboembolism (VTE) in major orthopaedic surgery compared to the low molecular weight heparin enoxaparin, when both were applied for 7 days after surgery. To compare the expected costs and clinical outcomes ... |
29,670 | Trousseau syndrome and the unknown cancer: use of positron emission tomographic imaging in a patient with a paraneoplastic syndrome. | Trousseau syndrome is defined as a migratory thrombophlebitis found typically in patients with an underlying malignancy. Conventional diagnostic testing and imaging can be used to successfully diagnose a primary malignancy in approximately 85% to 95% of patients. However, along with a comprehensive medical history and ... |
29,671 | Thrombosis and bleeding: when opposites are not so far apart. | Thrombotic events in patients with inherited bleeding disorders occur only rarely. However, in some cases, the co-existence of acquired or inherited prothrombotic risk factors may overcome the hypocoagulative state, modulating the clinical phenotype to a decrease in bleeding symptoms or even to an increase in the likel... |
29,672 | Effect of heparins on thrombin generation in hemophilic plasma supplemented with FVIII, FVIIa, or FEIBA. | Central venous catheters assist infusion of coagulation factors in hemophiliacs but can be problematic due to mechanical dysfunction, infection, and thrombosis. The effect of low molecular weight heparin, unfractionated heparin, or covalent antithrombin-heparin complex on thrombin generation in factor concentrate-suppl... |
29,673 | Straight talk about ovarian cancer. | Learn how to help patients recognize and defeat this insidious malignancy. |
29,674 | Extra hepatic portal vein obstruction leading to variceal bleed due to portal hypertension. | Portal Hypertension can be due to many causes other than cirrhosis. We report a case of extra hepatic portal vein obstruction leading to portal hypertension and varices, managed successfully by creating a Porto Caval shunt. |
29,675 | Novel antithrombotic strategies in cardiovascular diseases. | Ischemic cardiovascular diseases represent the most common cause of mortality and morbidity in the western world, and atherothrombosis occupies a central role in their pathophysiology. Venous thrombi, which form under low shear conditions, are predominantly composed of fibrin and red cells, while arterial thrombi form ... |
29,676 | Diffuse venous thromboemboli associated with IVIg therapy in the treatment of streptococcal toxic shock syndrome: case report and review. | Streptococcal toxic shock syndrome (STSS) is a severe invasive disease with a 40-80% mortality rate. Inflammatory cytokines induced by streptococcal pyrogenic exotoxins (SPEs) produce the clinical manifestations of a flu-like syndrome, followed by high fevers and multiorgan failure. Previously published reports have de... |
29,677 | Pregnancies and oral contraceptive therapy in severe (homozygons) FXII deficiency: a study in 12 patients and review of the literature. | Twelve women with severe Factor XII (FXII) deficiency were under observation for an average period of about 16 years. During this time, these women had 19 pregnancies without any bleeding or thrombotic complications. The evaluation of the literature has shown that three patients manifested deep vein thrombosis during p... |
29,678 | Budd-Chiari syndrome associated with visceral leishmaniasis and factor V Leiden mutation. | We here report a case of subacute Budd-Chiari syndrome (BCS) related to Factor V Leiden (FVL) mutation in the presence of visceral leishmaniasis. A 17-year-old man was admitted to hospital because of abdominal pain, pretibial edema and fever. The clinical picture of BCS had been developed within several months. BCS was... |
29,679 | Factor V Leiden in patients with venous thrombosis in Slovak population. | Resistance to activated protein C determined by factor V Leiden (FVL) is the most frequent inherited risk factor of venous thrombosis. The purpose of our work was to reveal the frequency of FVL in Slovak patients with venous thromboses, to characterise the nature of venous thromboses in this inherited thrombophilia, an... |
29,680 | Persistent falcine sinus in an adult: demonstration by MR venography. | The falcine sinus is a normal anatomic structure located in the falx cerebri that closes after birth and is rarely observed in the adult population. We describe a unique case of persistent falcine sinus in an adult who presented with venous sinus obstruction. |
29,681 | Spectrum of surgical complications after simultaneous pancreas-kidney transplantation in a prospectively randomized study of two immunosuppressive protocols. | Simultaneous pancreas-kidney transplantation (SPK) has evolved as an effective treatment for patients with end-stage nephropathy due to type 1 diabetes mellitus. This report analyses the spectrum of surgical complications among patients receiving tacrolimus and cyclosporin microemulsion (ME)-based therapy for SPK trans... |
29,682 | Anti-prothrombin IgG from patients with anti-phospholipid antibodies inhibits the inactivation of factor Va by activated protein C. | Interference of anti-phospholipid antibodies with the protein C pathway has been suggested to play a role in the development of thrombosis in the anti-phospholipid syndrome. We studied the effect of IgG preparations containing anti-prothrombin antibodies of 17 lupus anticoagulant-positive patients and 12 controls on th... |
29,683 | Local and systemic thrombolytic therapy for acute deep venous thrombosis. | This article presents a review of the treatment of lower-extremity deep venous thrombosis (DVT) with systemic and catheter-directed thrombolysis (CDT) and percutaneous mechanical thrombectomy (PMT). Standard treatment including anticoagulation therapy and compression stockings may not be entirely adequate, because a si... |
29,684 | Arterial misplacement of a femoral central venous catheter complicated with acute arterial occlusion. | Femoral vein catheterization is often carried out during resuscitation and in critical care units. It is usually achieved via a blind, external landmark-guided technique, through manual localization of the femoral artery. However, this approach can be challenging in patients with severe shock because of absence or ambi... |
29,685 | The role of ximelagatran in the treatment of venous thromboembolism. | Clinical-based evidence demonstrates that long-term oral anticoagulant therapy with the vitamin K antagonists is highly effective for the secondary prevention of venous thromboembolism (VTE). However, owing to fear of bleeding complications and the inconvenience of coagulation monitoring, many patients do not receive t... |
29,686 | Current issues in anticoagulation. | Anticoagulation therapy with unfractionated heparin, low-molecular-weight heparins and oral vitamin K antagonists is currently the mainstay of treatment and prevention of thromboembolic disorders (such as deep vein thrombosis, pulmonary embolism and stroke prevention in patients with atrial fibrillation). Although thes... |
29,687 | Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. | To assess the safety and efficacy of low-molecular-weight heparins (LMWHs) for thromboprophylaxis and treatment of venous thromboembolism (VTE) in pregnancy, a systematic review of studies to the end of 2003 was undertaken. Data on VTE recurrence and side effects were extracted and cumulative incidences of VTE and adve... |
29,688 | Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. | A 55 year old woman, known to have systemic lupus erythematosus and protein S deficiency, presented with sudden onset of visual loss in the left eye. Three days previously, she took a herbal phytoestrogen preparation for relief of her menopausal symptoms. Ophthalmological assessment showed a left inferior hemiretinal v... |
29,689 | Management of Budd-Chiari syndrome. | Thrombotic occlusion of the hepatic veins leads to liver dysfunction and liver failure requiring liver transplantation in advanced cases. The cause for the occlusion of the hepatic veins is not completely understood. However, several underlying conditions such as polycytemia, factor V Leiden mutation, and protein C and... |
29,690 | [Protective effect of ligusticum chuanxiong phthalides on focai cerebral ischemia in rats and its related mechanism of action]. | To study the protective effect of ligusticum chuanxiong phthalides on cerebral ischemia in rats and its related mechanism of action.</AbstractText>Middle cerebral artery occlusion (MCAO) model, thrombosis formation, platelet aggregation and hemorrheological parameters were measured to evaluate the protective effect of ... |
29,691 | Haemorheological alterations in Behçet's disease are not related to a tendency for venous thrombosis. | Behçet's disease is associated with an increased risk of thrombosis, although the prothrombotic mechanisms are unclear. Alterations in blood rheology, particularly increased erythrocyte aggregation, might play a role in the development of such thrombotic events.</AbstractText>We measured plasma lipids, fibrinogen,... |
29,692 | Effect of physical activity after recent deep venous thrombosis: a cohort study. | To determine whether increased physical activity 1 month after deep vein thrombosis (DVT) led to worsening of venous symptoms and signs within the subsequent 3 months.</AbstractText>By a multicenter prospective cohort study of patients with acute DVT, we used validated questionnaires at baseline, 1 month, and 4 months ... |
29,693 | Achieving and maintaining venous access for home parenteral nutrition. | Once chronic intestinal failure is established and home parenteral nutrition has become necessary, the patient's life is literally dependent on secure long-term central venous access, other than in the small group in whom intestinal transplantation is both appropriate and available. Means to preserve venous access are ... |
29,694 | A randomized trial of diagnostic strategies after normal proximal vein ultrasonography for suspected deep venous thrombosis: D-dimer testing compared with repeated ultrasonography. | With suspected deep venous thrombosis and normal results on proximal vein ultrasonography, a negative d-dimer result may exclude thrombosis and a positive D-dimer result may be an indication for venography.</AbstractText>To evaluate and compare the safety of 2 diagnostic strategies for deep venous thrombosis.</Abstract... |
29,695 | Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice. | Activated protein C resistance due to factor V Leiden (FVL) is a common genetic risk factor for venous thrombosis in humans. Although the impact of FVL on the development of venous thrombosis is well established, its effect on arterial thrombosis and atherosclerosis is controversial.</AbstractText>To determine the effe... |
29,696 | Mutation study of antithrombin: the roles of disulfide bonds in intracellular accumulation and formation of russell body-like structures. | Antithrombin (AT) is a major plasma protease inhibitor with three intramolecular disulfide bonds and a deficiency of it is associated with venous thrombosis. Recently, we prepared CHO cells overexpressing a novel mutant, AT(C95R), with a disulfide bond removed, and revealed that this mutant remained for a long time in ... |
29,697 | Blood flow velocity of the femoral vein with foot exercise compared to pneumatic foot compression. | To compare the effects of foot exercise with an intermittent pneumatic foot compression (IPC) device on blood flow velocity of the femoral veins.</AbstractText>Prospective, controlled study.</AbstractText>General intensive care unit of a university hospital.</AbstractText>20 patients on bed rest in the intensive care u... |
29,698 | Transitory sleep spindles impairment in deep cerebral venous thrombosis. | Sleep spindles may be affected by thalamic or hemispheric ischemic stroke. However, spindles reduction and their relationship with K-complexes following deep cerebral venous thrombosis have not been reported. An 18-year-old woman suffered from a deep cerebral venous thrombosis with vasogenic oedema located predominantl... |
29,699 | [Successful recanulization of superior venous vessels: a new challenge for interventional pediatric cardiology]. | The use of long-term central venous catheters is a routine in chronic pediatric diseases. Thrombotic complications progressively reduce the central venous capital and hamper the long-term management of these patients.</AbstractText>We report two cases of obstruction of the central upper venous system and discuss of the... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.