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30,700 | Antithrombotic effect of L-arginine in hypertensive rats. | The aim of the study was to evaluate the effect of L-arginine (L-Arg) on haemostasis in stasis model of venous thrombosis in renal hypertensive rats. The effect of the single dose (i.v. 300 mg/kg bolus+300 mg/kg/h) and of the 10-day application (p.o. 1 g/kg, once daily) of L-Arg was determined. L-Arg reduced the blood ... |
30,701 | Morbidity of lupus anticoagulants in children: a single institution experience. | The lupus anticoagulant (LA) and the anticardiolipin antibodies (ACA) are the antiphospholipid antibodies more relevant clinically. Their clinical manifestations are diverse with most patients being asymptomatic while others present venous or arterial thrombosis, and more rarely, bleeding. Our objectives were to evalua... |
30,702 | Peripancreatic vascular abnormalities complicating acute pancreatitis: contrast-enhanced helical CT findings. | To determine the prevalence and morphologic helical computed tomography (CT) features of peripancreatic vascular abnormalities in patients with acute pancreatic inflammatory disease in correlation with the severity of the pancreatitis.</AbstractText>One hundred and fifty-nine contrast-enhanced helical CT scans of 100 c... |
30,703 | [Hormone replacement therapy and venous thromboembolism]. | Venous thromboemboembolism is a multigenic and a multifactorial disease. Several genetic risk factors have been identified: antithrombin, protein C and protein S deficiencies, and molecular defects in factor V gene (factor V Leiden) or factor II gene (G 20210A transition). Retrospective and prospective studies have dem... |
30,704 | Progress in the development of synthetic thrombin inhibitors as new orally active anticoagulants. | The trypsin-like serine protease thrombin is a multifunctional key enzyme at the final step of the coagulation cascade and is involved in the regulation of hemostasis and thrombosis. An increased activation of coagulation can result in severe thromboembolic disorders, one of the major reasons responsible for mortality ... |
30,705 | The use of antibodies to coagulation factors for anticoagulant therapy. | Current treatments for preventing thrombotic diseases are associated with a significant risk of bleeding. Improved anticoagulant agents are therefore still required. The specificity and pharmacokinetics properties of monoclonal antibodies to coagulation factors allow novel anticoagulation approaches. Treatment with hum... |
30,706 | [Possibility of diagnosis and treatment of thrombotic complications in primary mediastinal B-cell lymphosarcoma]. | Efficacy of the treatment of primary mediastinal B-cell lymphosarcoma depends to a great extent on early diagnosis and treatment policy. In this study we evaluated possibilities of diagnosis and treatment of thrombotic complications of primary mediastinal B-cell lymphosarcoma (PMBL).</AbstractText>61 patients were exam... |
30,707 | Oromandibular reconstruction with vascularized free flaps: a review of 50 cases. | Fifty cases of oromandibular reconstruction using vascularized free flaps to evaluate functional parameters of results were evaluated. There were 23 iliac crest flaps, 17 fibula flaps, 30 ulnar forearm flaps, and 3 radial forearm flaps with bone. Thirteen female and 37 male patients comprised the study, with a mean age... |
30,708 | A case of antiphospholipid syndrome presenting with pulmonary truncus and main pulmonary artery thrombosis. | In patients with antiphospholipid syndrome (APS), thromboembolism and pulmonary hypertension are the most common pulmonary manifestations. Thrombotic obstruction at the level of the main and/or proximal pulmonary arteries is rare. We report a 40-year-old woman without any history of previous arterial and/or venous thro... |
30,709 | Aggressive systemic mastocytosis mimicking sclerosing cholangitis. | A 43 year-old woman presented with fever, abdominal pain, epato-splenomegaly, ascites, cholestasis, anemia, thrombocytopenia and previous diagnosis of sclerosing cholangitis based on liver biopsy and endoscopic retrograde cholangiopancreatography(ERCP). The bone marrow biopsy and the revision of liver biopsy using anti... |
30,710 | Recombinant human erythropoietin and the risk of thrombosis in patients receiving thalidomide for multiple myeloma. | Among 199 patients treated with thalidomide for multiple myeloma, four thromboses occurred in 49 cases during erythropoietin therapy (prevalence 8.1%; annual rate 7.25%), and another 14 events occurred in patients not on erythropoietin (9.3%; 7.56%). Thus, erythropoietin would seem not to increase the risk of thrombosi... |
30,711 | Acute Budd-Chiari syndrome with liver failure: the experience of a policy of initial interventional radiological treatment using transjugular intrahepatic portosystemic shunt. | The optimal management of acute Budd-Chiari syndrome (BCS) with liver failure is controversial. Options include anticoagulation, portal systemic shunting or liver transplantation. In recent years, transjugular intrahepatic portosystemic shunts (TIPS) have been tried in place of shunt surgery. We report our experience w... |
30,712 | A model for cardiopulmonary bypass redesign. | A portion of patients undergoing cardiac surgery may develop focal and/or subtle brain injuries secondary to cardiac surgery. There is evidence that, in some cases, these injuries may be related to cardiopulmonary bypass (CPB). Embolism and hypoperfusion are the dominant mechanisms for focal neurologic injuries among c... |
30,713 | Trends in hospital admission for stroke in Calgary. | Stroke incidence has fallen since 1950. Recent trends suggest that stroke incidence may be stabilizing or increasing. We investigated time trends in stroke occurrence and in-hospital morbidity and mortality in the Calgary Health Region.</AbstractText>All patients admitted to hospitals in the Calgary Health Region betwe... |
30,714 | New insights into the development of popliteal cysts. | This prospective study was designed to investigate the aetiology of popliteal (Baker's) cysts.</AbstractText>Some 426 legs in 312 individuals were investigated with ultrasonography for the presence of a popliteal cyst. Participants included healthy volunteers, patients with a painful knee, and a group of patients with ... |
30,715 | [New criteria for the diagnostic and treatment of the deep vein thrombosis of the lower limbs]. | The diagnosis of the deep vein thrombosis (DVT) based exclusively on its symptomatology and on the examination clinic is of few usefulness due to its small sensibility and especificity. However, its adequate combination with the presence of risk factors for the thrombosis, and the existence or not of an alternative dia... |
30,716 | The antiphospholipid syndrome and endothelial function. | Endothelial function and vascular inflammation play major roles in the pathogenesis and clinical outcome of patients with the antiphospholipid syndrome. |
30,717 | Oral contraceptive use and smoking habits in young Israeli women: a cross-sectional study. | Oral contraceptive users are at increased risk for both arterial and venous thrombosis, some of which can be fatal. Studies are consistent with the existence of a synergism between cigarette smoking and OC use in the pathogenesis of myocardial infarction in young women.</AbstractText>To study the relationship between O... |
30,718 | [Unclear liver fibrosis in a 42-year-old patient with polycythemia vera]. | A 42-year-old patient was admitted to hospital because of ascites and polyglobulia. Laboratory tests revealed reduced liver function and a significant elevation of all three hematopoietic cell lines. Liver fibrosis and polycythemia vera were diagnosed by histologic examination. The most frequent causes for liver fibros... |
30,719 | Ureteral necrosis after kidney transplantation: risk factors and impact on graft and patient survival. | Ischemia, the main cause of ureteral necrosis in renal transplantation, cannot alone explain the late occurrence of some fistulas beyond the first postoperative month. The aim of this study, performed on a cohort of 1,629 consecutive kidney transplantations, was to analyze the risk factors implicated in the occurrence ... |
30,720 | A case of thrombosis mimicking a buccal tumour: usefulness of MRI. | A rare case of thrombosis mimicking a tumour in the buccal region is reported. Since the entire round mass was located deeply, it was difficult to diagnose. Contrast computed tomography, magnetic resonance imaging (MRI) and ultrasound examinations may be useful, but MRI was most useful in this case because it allowed p... |
30,721 | The association of antibodies to cardiolipin, beta 2-glycoprotein I, prothrombin, and oxidized low-density lipoprotein with thrombosis in 292 patients with familial and sporadic systemic lupus erythematosus. | To determine the prevalence of antibodies to phospholipid-binding plasma proteins (aPL) and to oxidized low-density lipoprotein (OX-LDL), and to study the association of these antibodies with thrombosis and coronary heart disease (CHD) in patients with systemic lupus erythematosus (SLE).</AbstractText>Clinical data and... |
30,722 | [Thromboembolic complications in patients undergoing in vitro fertilization: retrospective clinical study]. | To determine the incidence and the type thromboembolic complications in patients undergoing in vitro fertilization (IVF). To evaluate their clinical course, the influence on reproductive outcomes, and the prevalence of thrombophilia in these women.</AbstractText>Retrospective clinical study.</AbstractText>Assisted Repr... |
30,723 | Thrombectomy discloses intravascular growth of chondroid liposarcoma mimicking a long distance vena cava thrombosis. | A 22-year-old woman with a newly detected chondroid liposarcoma located in the iliac muscle was diagnosed as having bilateral pulmonary embolism. Gadolinium-enhanced MRI further revealed a long distance thrombus reaching from the iliac vein to the right atrium. The thrombus was attributed to a hypercoagulability state ... |
30,724 | Constrictive pericarditis associated with right atrial and major venous thrombosis. | Right atrial thrombi are very rare. Existence of right atrial thrombus with constrictive pericarditis is even rarer. Only few cases have been reported in the English literature. Here, we report an unusual case of constrictive pericarditis complicated with right atrial and major venous thrombi. The patient underwent a s... |
30,725 | Dementia associated with the antiphospholipid syndrome: clinical and radiological characteristics of 30 patients. | To analyse the clinical and radiological characteristics of patients with dementia associated with the antiphospholipid syndrome (APS).</AbstractText>Twenty-five patients were identified by a computer-assisted (MEDLINE, National Library of Medicine, Bethesda, MD) search of the literature to locate all cases of dementia... |
30,726 | Weekly paclitaxel combined with pegylated liposomal doxorubicin (CaelyxTM) given every 4 weeks: dose-finding and pharmacokinetic study in patients with advanced solid tumors. | We aimed to define the maximum tolerated dose (MTD) and characterize the toxicity of the combination of pegylated liposomal doxorubicin (PLD; Caelyx trade mark ) and weekly paclitaxel (wPTX), and to investigate pharmacokinetics of PLD in this combination.</AbstractText>A phase I study was performed with an initial dose... |
30,727 | The risk of venous thromboembolic disease in patients with monoclonal gammopathy of undetermined significance. | Recent evidence indicates that patients with multiple myeloma receiving combination chemotherapy containing thalidomide are at a significantly high risk for venous thromboembolic disease (VTD). However, information on the occurrence of VTD in a related disorder, benign monoclonal gammopathy of undetermined significance... |
30,728 | Validation of a clinical guideline on prevention of venous thromboembolism in medical inpatients: a before-and-after study with systematic ultrasound examination. | Clinical practice guidelines on prevention of venous thromboembolism in medical inpatients have been implemented in various settings, although few studies have assessed their impact on venous thromboembolism events.</AbstractText>To determine whether the implementation of a locally developed guideline is followed by ch... |
30,729 | Design and synthesis of a short-chain bitistatin analogue for imaging thrombi and emboli. | Previously, we showed that labeled bitistatin analogues possessed excellent characteristics for imaging both deep-vein thrombosis and pulmonary embolism. We hypothesized that the N-terminal amino acid sequence of bitistatin, which is different from other disintegrins, likely interacts with the binding site of platelets... |
30,730 | Thromboembolic prophylaxis as a risk factor for postoperative complications after breast cancer surgery. | Hematoma and bruising (sugillation) are frequent problems after operations for primary breast cancer. In the present study we evaluated the influence of various methods of perioperative thromboembolic prophylaxis on the postoperative incidence of hematoma and suggilation. From June 1994 through August 1996, a series of... |
30,731 | [Sudden death due to massive pulmonary thromboembolism after pneumonectomy; report of a case]. | A 76-year-old woman underwent a left pneumonectomy for a primary adenocarcinoma. On the fourth postoperative day, when walking to the toilet, she suddenly developed syncope followed by dyspnea and cardiopulmonary arrest. Although we performed cardiopulmonary resusciation, she died 1 hour later. With her family's approv... |
30,732 | Urokinase for restoring patency of malfunctioning or blocked central venous catheters in children with hemato-oncological diseases. | To evaluate differences in success rate between two dosages of intraluminal urokinase (IL-UK) for treatment of withdraw occlusion in central venous catheters (CVC) and to confirm the efficacy of a salvage protocol with low-dose systemic urokinase (S-UK) in case of failure of IL-UK or of complete catheter obstruction.</... |
30,733 | Port-a-Cath complicated by right atrial thrombus. Minimally invasive thrombectomy without cardiopulmonary bypass. | Right atrial thrombosis during chemotherapy is commonly treated conservatively. We describe a minimally invasive surgical procedure to remove a right atrial thrombus in a patient with a history of recurrent lung embolism. Surgery was performed through a mini-thoracotomy without cardiopulmonary bypass during occlusion o... |
30,734 | Prolonged enoxaparin therapy to prevent venous thromboembolism after primary hip or knee replacement. A cost-utility analysis. | Among patients undergoing elective total hip or knee replacement, prolonged prophylaxis with low-molecular-weight heparin significantly reduces the risk of symptomatic venous thromboembolism. Whether implementing routine prolonged prophylaxis is cost-effective remains uncertain.</AbstractText>We performed an economic m... |
30,735 | Klinefelter's syndrome presenting with leg ulcers. | A 54-year-old man of Persian origin presented to our department with a 1-year history of ulcers on the right leg that had been unresponsive to numerous topical treatments, accompanied by lymphedema of the right leg. Medical history included hypergonadotropic hypogonadism, which had not been further investigated. He was... |
30,736 | Pulmonary thromboembolism in American Indians and Alaskan Natives. | The rate of diagnosis of deep venous thrombosis and/or pulmonary embolism (collectively, venous thromboembolism: VTE) among patients discharged from Indian Health Service hospital care from 1980 through 1996 was considerably lower than rates reported in African Americans or whites. Expansion of the national census in 1... |
30,737 | Change in thrombus length on venous ultrasound and recurrent deep vein thrombosis. | Despite successful treatment, deep vein thrombosis may not fully resolve in some patients. Consequently, in patients with new symptoms in a previously affected leg, noncompressibility on ultrasound cannot be assumed to be due to recurrent thrombosis; therefore, we sought to determine interobserver agreement on ultrasou... |
30,738 | Endovascular management of iliofemoral venous occlusive disease. | New developments in the management of both acute and chronic iliac vein occlusive disease offer exciting options for the treatment of this often debilitating condition. Percutaneous clot removal using thrombolysis, mechanical thrombectomy, or a combination of the two is fast becoming the treatment of choice for patient... |
30,739 | Perioperative management of the post-gastric-bypass patient presenting for body contour surgery. | Bariatric surgery has evolved as an effective and relatively safe treatment for morbid obesity. With nearly every region of the body as a potential operative site and an unprecedented number of surgical procedures available, we must give attention to thoughtful perioperative management. Bariatric surgery is a life-chan... |
30,740 | The role of uracil-tegafur (UFT) in elderly patients with colorectal cancer. | 5-Fluorouracil (5-FU) administered in several schedules since its introduction in 1957 continues to be an integral part of standard first-line therapy for colorectal cancer. Continuous intravenous (i.v.) infusion appears to yield improved response rate and overall survival, with fewer adverse effects compared with i.v.... |
30,741 | [Portal venous and enteric drainage in simultaneous pancreas kidney transplantation]. | To summarize the initial experience of simultaneous pancreas kidney transplantation (SPK) with portal venous and enteric drainage.</AbstractText>Between Jane 2001 and Jane 2003, SPK were performed in 5 patients. Systemic venous-enteric drainage (SED) was used in the first 2 patients and portal venous-enteric drainage (... |
30,742 | [Diagnosis and treatment of renal cell carcinoma with vena cava tumor thrombi]. | <AbstractText Label="BACKGROUND & OBJECTIVE" NlmCategory="OBJECTIVE">Renal cell carcinoma (RCC) might involve the renal vein, and form tumor thrombus extending into the vena cava or the right atrium. Treating RCC with vena cava involvement is difficult in clinical practice. Radical nephrectomy with complete tumor t... |
30,743 | [Preliminary study on orthotopic liver transplantation for treatment of advanced hepatocellular carcinoma without extra-hepatic metastasis - a report of 10 cases]. | <AbstractText Label="BACKGROUND & OBJECTIVE" NlmCategory="OBJECTIVE">Most cases of hepatocellular carcinoma (HCC) are unresectable even without extra-hepatic metastasis. In addition, about 80%-90% patients in China are accompanied with cirrhosis. Liver transplantation is probably more proper for these patients than... |
30,744 | Enoxaparin can be used safely in patients with severe thrombocytopenia due to intensive chemotherapy regimens. | Treatment with intensive chemotherapy regimens is frequently complicated by severe thrombocytopenia. During the period of severe thrombocytopenia, anticoagulant treatment is not uncommonly indicated for thromboembolic events or thromboprophylaxis in these patients. We report 10 hematological patients treated with inten... |
30,745 | Portal vein thrombosis in children and adolescents: the low prevalence of hereditary thrombophilic disorders. | The aim of this study was to determine the frequency of thrombophilic disorders in children and adolescents with portal vein thrombosis (PVT) as well as assessing the hereditary character of this disorder.</AbstractText>A 2-year prospective study was carried out in pediatric PVT patients (n = 14), their parents (n = 25... |
30,746 | Chronic external iliac vein obstruction as a cause of leg ulceration. | Chronic venous leg ulceration, which tends to recur, is difficult to treat and therefore needs special diagnostic and therapeutic care. We recently treated a 45-year-old patient with an obstruction of the left external iliac vein, caused by deep venous thrombosis. We would like to propose that, although rare, the exist... |
30,747 | Lower ambient temperature was associated with an increased risk of hospitalization for stroke and acute myocardial infarction in young women. | Results of investigations into the impact of seasonal variation on the incidence of cardiovascular diseases (CVD) have been inconsistent. Using the WHO Collaborative Study of CVD and Steroid Hormone Contraception database, we attempted to examine the relationship between variation in three climatic variables and risk o... |
30,748 | Repeated-measures modeling improved comparison of diagnostic tests in meta-analysis of dependent studies. | Current methods for meta-analysis of diagnostic tests do not allow utilizing all the information from papers in which several tests have been studied on the same patient sample. We demonstrate how to combine several studies of diagnostic tests, where each study reports on more than one test and some tests (but not nece... |
30,749 | Consensus recommendations for use of central venous access devices in haemophilia. | Venous access is essential for delivery of haemophilia factor concentrate. Wherever possible, peripheral veins remain the route of choice, and the use of central venous access devices (CVADs) should be limited to cases of clear need in patients with caregivers able to exercise diligence in CVAD care and should continue... |
30,750 | Cutaneous manifestations associated with antiphospholipid antibodies. | Primary Antiphospholipid Antibody Syndrome (PAAS) is characterized by detection of antiphospholipid antibodies associated with venous or arterial thrombosis and/or miscarriages by patients with no other associated disease such as systemic lupus erythematosus (SLE). Primary Antiphospholipid Antibody Syndrome has many cl... |
30,751 | Indwelled femoral vein non-cuffed, double-lumen hemodialysis catheter complicated by pulmonary thromboembolism. | Non-cuffed, double-lumen hemodialysis (HD) catheters can be inserted at the bedside in the femoral, internal jugular or subclavian position. The femoral route is less risky, and the incidence of life-threatening complications is lower for femoral cannulation than for internal jugular and subclavian cannulations. Howeve... |
30,752 | Pronto ThromboRisk--a novel primer-extension ELISA based assay for the detection of mutations associated with increased risk for thrombophilia. | The role of inherited thrombophilias in the pathogenesis of thrombosis, and their relation to thromboembolic events and pregnancy complications, has escalated the demand for molecular testing. We employed the new Pronto ThromboRisk kit (Pronto Diagnostics Ltd., Rehovot, Israel), which is based on a novel primer-extensi... |
30,753 | Prospective evaluation of outcome measures in free-flap surgery. | Free-flap failure is usually caused by venous or arterial thrombosis. In many cases, lack of experience and surgical delay also contribute to flap loss. The authors prospectively analyzed the outcome of 57 free flaps over a 28-month period (January, 1999 to April, 2001). The setting was a university hospital tertiary r... |
30,754 | Elevated plasma factor VIII and D-dimer levels as predictors of poor outcomes of thrombosis in children. | Elevated levels of plasma factor VIII and D-dimer predict recurrent venous thromboembolism in adults. We sought to determine whether an elevation of factor VIII, D-dimer, or both at diagnosis and persistence of the laboratory abnormality after three to six months of anticoagulant therapy correlate with poor outcomes of... |
30,755 | [Relationship of plasma homocysteine and folic acid levels and 5,10-methylenetetrahydrofolate reductase gene mutation with venous thromboembolism]. | To investigate the association between concentrations of plasma homocysteine and folic acid, 5,10-methylenetetrahydrofolate reductase (MTHFR) C667T mutation and venous thromboembolism (VTE) and to analyze the effect of MTHFR C667T mutation on concentrations of plasma homocysteine and folic acid.</AbstractText>In 58 pat... |
30,756 | Compression of the iliac vein by a synovial cyst. | While a synovial cyst of the hip is a rare cause of lower limb swelling, a differential diagnosis of deep vein thrombosis is needed. A case of lower limb swelling due to compression of the external iliac vein by a synovial cyst is presented with a review of the literature. Sagittal views and three-dimensional images of... |
30,757 | Expanding options for bedside placement of inferior vena cava filters with intravascular ultrasound when transabdominal duplex ultrasound imaging is inadequate. | Although bedside placement of inferior vena cava (IVC) filters by means of transabdominal duplex ultrasound is possible in most patients, those with inadequate visualization have traditionally required fluoroscopy. The purpose of this study was to assess the safety and efficacy of bedside IVC filter placement with intr... |
30,758 | Validation and application of an automated 96 -well solid-phase extraction liquid chromatography-tandem mass spectrometry method for the quantitative determination of SCH 201781 in human plasma. | SCH 201781 is a direct thrombin inhibitor recently under study in clinical trials to determine its safety and efficacy for the treatment of venous and arterial thrombosis. In aqueous solution, SCH 201781 exists as three forms, a ring-opened hydrated form and two ring-closed diastereomers. An automated solid-phase extra... |
30,759 | [Management of postoperative compartment syndrome -- case report]. | Differential diagnosis and management of the lower extremity compartment syndrome as a potentially devastating complication of prolonged surgery in the lithotomy position.</AbstractText>A 55-year-old patient underwent radical cystoprostatovesiculourethrectomy including reconstruction of an ileal conduit because of a mu... |
30,760 | Catheter interventional therapy in an elderly patient with deep vein thrombosis and a brain tumor. | A 92-year-old woman with a brain tumor developed swelling of the left lower extremity. Venography showed considerable thrombi from the left common iliac vein to the femoral vein. Following implantation of a temporary inferior vena cava filter, catheter aspiration therapy and catheter-directed thrombolysis were performe... |
30,761 | Upper-extremity deep vein thrombosis: a prospective registry of 592 patients. | Upper-extremity deep vein thrombosis (UEDVT) occurs spontaneously or sometimes develops as a complication of pacemaker use, long-term use of a central venous catheter (CVC), or cancer.</AbstractText>To improve our understanding of UEDVT, we compared the demographics, symptoms, risk factors, prophylaxis, and initial man... |
30,762 | High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11. | High factor VIII (FVIII) levels are known to be a risk factor for deep venous thrombosis, but the mechanisms responsible for high FVIII levels remain unclear. Here, a new phenotype "FVIII level residuum" (FVIII-R) was defined in order to eliminate the impact of common determinants on FVIII levels. We studied 13 familie... |
30,763 | The femoral gateway. | A patient who abused cocaine intravenously had an abscess in the groin, which healed to form a sinus tract leading directly to the wall of the femoral vein. She used this "gateway" as her primary means of venous access for the next 5 years. It was both "painless and brainless" and led to femoral vein thrombosis and sep... |
30,764 | Prevention of central venous line-related thrombosis by continuous infusion of low-dose unfractionated heparin, in patients with haemato-oncological disease. A randomized controlled trial. | We have conducted a prospective randomized controlled trial to evaluate the role of low-dose unfractionated heparin prophylaxis in preventing central venous line-related thrombosis in patients with haemato-oncological disease. Patients were randomly assigned to receive either prophylactic intravenous unfractionated hep... |
30,765 | Murine thrombosis models. | Due to exciting advances in molecular biology, the laboratory mouse has become an important and frequently used model for studying thrombosis. This article reviews several experimental approaches that have been used to study arterial, venous, and microvascular thrombosis in mice. The advantages and limitations of diffe... |
30,766 | Compliance matching stent placement in the carotid artery of the swine promotes optimal blood flow and attenuates restenosis. | We assessed the value of a gradient-compliant stent in an animal model.</AbstractText>Bilateral carotid arteries were stented with nitinol stents having variable-oversizing, variable-stiffness, and with (CMS, 10 animals) and without (SMART, four animals) compliance-matching endings. Angiography, hemodynamic, scanning-e... |
30,767 | The management of short saphenous varicose veins: a survey of the members of the vascular surgical society of Great Britain and Ireland. | The outcome of short saphenous vein surgery is often unsatisfactory and the high litigation rate reflects this. The aim of this study was to explore the current management of short saphenous varicose veins in Great Britain and Ireland.</AbstractText>This was a postal questionnaire survey of the surgical members of the ... |
30,768 | Preservation of venous valve function after catheter-directed and systemic thrombolysis for deep venous thrombosis. | The aim of the study was to assess venous reflux and the obstruction pattern after catheter-directed and systemic thrombolysis of deep iliofemoral venous thrombosis.</AbstractText>Thirty-two patients treated either with systemic (16) or catheter-directed local thrombolysis (16) for massive iliofemoral thrombosis were i... |
30,769 | Liver transplantation in Medellin, Colombia: initial experience. | The goal of this article is to present the experience of a new liver transplant team.</AbstractText>This review includes all patients who received a liver transplant between March 15, 2000 and March 15, 2003.</AbstractText>We performed 87 transplantations on 84 patients; 39 were females and 45 were males of average age... |
30,770 | Spermatic vein tumor thrombus in renal cell carcinoma. | Renal cell carcinoma has the tendency to form venous thrombi. This may involve the renal veins or the inferior vena cava and may extend cephalad/antegrade into the right atrium. We report a patient with renal cell carcinoma who had an intracaval tumor thrombus that had extended into the right spermatic vein. We believe... |
30,771 | Bilateral anterior ischemic optic neuropathy after liposuction.<Pagination><StartPage>211</StartPage><EndPage>213</EndPage><MedlinePgn>211-3</MedlinePgn></Pagination><Abstract><AbstractText>A 30-year-old woman had bilateral anterior ischemic optic neuropathy after undergoing large-volume liposuction. Visual function re... | A 30-year-old woman had bilateral anterior ischemic optic neuropathy after undergoing large-volume liposuction. Visual function remained stable over a four-month follow-up, with decreased visual acuity and marked constriction of the visual fields. To our knowledge, this is the second reported case of ischemic optic neu... |
30,772 | Clinical significance of anticardiolipin and anti-beta2-glycoprotein I antibodies. | Anticardiolipin (aCl) and anti-beta2-glycoprotein I (anti-beta2-gpI) antibodies are autoantibodies associated with the antiphospholipid syndrome (APS), which is characterized by both arterial and venous thrombosis and miscarriages. The scope of this study was to explore the clinical characteristics of patients with aCl... |
30,773 | The development and application of a surface plasmon resonance-based inhibition immunoassay for the determination of warfarin in plasma ultrafiltrate. | Warfarin is the most widely prescribed oral anticoagulant for the management of a wide variety of thromboembolic disorders such as atrial fibrillation and deep vein thrombosis. A panel of warfarin-protein conjugates were produced and characterised and subsequently used for the production of monoclonal antibodies to war... |
30,774 | Neonatal venous cerebral hemorrhage. Report of two cases. | Intracranial pathological changes can occur as a result of impaired craniocervical venous return. Thrombosis of central venous access catheters was demonstrated in two neonates born at 38 and 27 weeks' gestation. Neither infant developed hemorrhage of prematurity as confirmed on cranial ultrasonography. Clinical eviden... |
30,775 | Spontaneous intracerebral hemorrhage: a review. | Spontaneous intracerebral hemorrhage (SICH) is a blood clot that arises in the brain parenchyma in the absence of trauma or surgery. This entity accounts for 10 to 15% of all strokes and is associated with a higher mortality rate than either ischemic stroke or subarachnoid hemorrhage. Common causes include hypertension... |
30,776 | [Therapeutic education of patients receiving anticoagulants for thromboembolic venous disease: description of the Educ'AVK program]. | Educ'AVK is an education program designed for patients starting an oral anticoagulant treatment following a thromboembolic event (deep venous thrombosis or pulmonary embolism). Patients enrolled are judged capable of self-management of their drug treatment. The intervention, adapted to a short-term treatment, consists ... |
30,777 | [Management of venous thromboembolic disease in ambulatory and hospital settings: an assessment of general practices in France]. | In spite of increasing use of prophylactic treatments, venous thromboembolic disease (VTD) remains an important public health problem because of its high morbidity and mortality, in particular after major orthopedic surgery. The aim of this study is to provide an assessment of current medical management of VTD and post... |
30,778 | Low molecular weight heparin in the treatment of venous and arterial thromboses in the premature infant. | Thrombosis in the preterm newborn is a growing problem, a result of improved survival of the smallest and sickest infants. Treatment with low molecular weight heparin (LMWH) has potential advantages, including predictable pharmacokinetics, subcutaneous administration, and minimal monitoring. However, studies with LMWH ... |
30,779 | Methyl-methacrylate bone cement surface does not promote platelet aggregation or plasma coagulation in vitro. | Leakage of viscous bone cement into venous blood possibly resulting in pulmonary embolism may occur during percutaneous vertebroplasty. Our aim was to study if bone cement surface or cement liquid component could induce platelet aggregation or plasma coagulation in vitro. Two types of commonly used methyl-methacrylate ... |
30,780 | Patient preferences for capillary vs. venous INR determination in an anticoagulation clinic: a randomized controlled trial. | Patients who are receiving warfarin therapy require frequent blood testing to monitor the intensity of anticoagulation. Although previous studies suggest that capillary blood monitoring of the international normalize ratio (INR) is rapid and reliable, patient preferences for the method of blood drawing have not been in... |
30,781 | An open-label, comparative study of the efficacy and safety of once-daily dose of enoxaparin versus unfractionated heparin in the treatment of proximal lower limb deep-vein thrombosis. | Treatment of deep-vein thrombosis (DVT) with a once-daily regimen of enoxaparin, rather than a continuous infusion of unfractionated heparin (UFH) is more convenient and allows for home care in some patients. This study was designed to compare the efficacy and safety of these two regimens for the treatment of patients ... |
30,782 | Extended treatment for venous thromboembolism: how long is long enough? | The long-term aim of treatment of venous thromboembolism (VTE) is the prevention of late recurrences and the post-thrombotic syndrome. The optimal duration of oral anticoagulant therapy after VTE is still controversial. Patients are currently stratified into risk categories for recurrence on the basis of clinical chara... |
30,783 | New anticoagulants and their potential impact on the treatment of thromboembolic disease. | Traditional anticoagulants have drawbacks that make them complex to manage, limit their usefulness, and increase the possibility of adverse events. New anticoagulants are being developed that directly target a single coagulation factor. The agents have improved pharmacokinetics and pharmacodynamics and may not need coa... |
30,784 | [A 77-year-old patient with suspected left atrial tumor]. | A 77-year-old female presented with a suspected cardiac tumor and thrombosis of both legs diagnosed by phlebography with pulmonary embolism of both sides. In transthoracic echocardiography, transesophageal echocardiography, and CT no intracardial tumor was seen. There was a hiatal hernia which compressed the left atriu... |
30,785 | Invasive approaches to treatment of venous thromboembolism. | Deep vein thrombosis (DVT) occurs in one-quarter of a million individuals annually in the United States and results in significant disability from pulmonary embolism and chronic venous insufficiency, especially when the proximal iliofemoral is involved. Treatment has centered on early institution of adequate anticoagul... |
30,786 | New anticoagulants for treatment of venous thromboembolism. | Treatment of venous thromboembolism (VTE) usually starts with concomitant administration of heparin or low-molecular-weight heparin (LMWH) and a vitamin K antagonist. The parenteral anticoagulant, which is given for at least 5 days, is stopped once the vitamin K antagonist produces a therapeutic level of anticoagulatio... |
30,787 | Long-term management of patients after venous thromboembolism. | Long-term treatment of venous thromboembolism (VTE) focuses mainly on the duration of anticoagulant therapy, usually with vitamin K (VK) antagonists. The duration of therapy should be individualized based on the risk of recurrent VTE if treatment were stopped and the risk of bleeding if treatment were continued. The ri... |
30,788 | Initial treatment of venous thromboembolism. | Adequate initial anticoagulant therapy of deep venous thrombosis (DVT) is required to prevent thrombus growth and pulmonary embolism (PE). Intravenous unfractionated heparin (UFH) is being replaced by low-molecular-weight heparin (LMWH) as the anticoagulant of choice for initial treatment of venous thromboembolism (VTE... |
30,789 | Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. | Leukocytes and leukocyte-derived microparticles contain low levels of tissue factor (TF) and incorporate into forming thrombi. Although this circulating pool of TF has been proposed to play a key role in thrombosis, its functional significance relative to that of vascular wall TF is poorly defined. We tested the hypoth... |
30,790 | Tamoxifen for breast cancer prevention: a framework for clinical decisions. | Given the potential side effects and an uncertain survival benefit, decisions about tamoxifen treatment for the primary prevention of breast cancer remain complex. Primary care providers, including gynecologists, will need to counsel patients regarding this form of preventive care. In this report, we update cost-effect... |
30,791 | [Effects of fraction from Phyllanthus urinaria on thrombosis and coagulation system in animals]. | To investigate the effects of PUW (a fraction containing 60% corilagin from a Chinese herbal plant Phyllanthus urinaria) on thrombosis and coagulation system.</AbstractText>Myers's method was used to evaluate the protection of intravenously administered PUW against the male mouse sudden death caused by injection of 75 ... |
30,792 | Candida kefyr, an uncommon but emerging fungal pathogen: report of two cases. | Although Candida species are present as normal microflora of the human host, alterations in host defenses can lead to development of disease. Candida infections, ranging from urinary tract infections to bloodstream infections, are common in patients in the intensive care unit. Infections with non-albicans Candida sp ar... |
30,793 | Upper-extremity deep-vein thrombosis following a clavicular fracture. | Upper-extremity deep-vein thrombosis (DVT) is not frequently reported in orthopaedic literature. We report a case of upper-limb DVT following an acute clavicular fracture that was treated conservatively with a figure-of-eight sling. Diagnosis of this condition requires a high index of suspicion, and treating it would p... |
30,794 | Wide surgical excision for osteoid osteoma. Should it be the first-choice treatment? | Osteoid osteomas (OO) are benign skeletal tumors with a predilection for the long bones of young patients. Many different methods are used for their treatment, conservative or operative, less or more radical, with variable technology applications to destroy the "nidus." We present 38 patients with OO who were treated i... |
30,795 | Portal vein resection for a portal vein thrombus caused by nonfunctioning islet cell carcinoma: report of a case. | We report a case of nonfunctioning islet cell carcinoma of the pancreas causing a tumor thrombus in the portal vein. The patient was a 60-year-old woman whose presenting symptoms were abdominal pain, vomiting, and weight loss. We performed a subtotal pancreatectomy and splenectomy combined with partial resection of the... |
30,796 | Transcranial Doppler imaging in children: sickle cell screening and beyond. | Transcranial Doppler (TCD) is widely accepted as the modality of choice for screening intracranial vessels in children with sickle cell disease. Its advantages are that it is noninvasive (no need for sedation, contrast material, or radiation), portable, easily repeated, and it provides information about the intracrania... |
30,797 | Deep vein thrombosis resolution is not accelerated with increased neovascularization. | Deep venous thrombosis (DVT) resolution involves fibrinolysis, neovascularization, and fibrosis. We hypothesized that promoting neovascularization would accelerate DVT resolution.</AbstractText>A rat model of stasis DVT was produced with proximal ligation of the inferior vena cava (IVC) and all visible tributaries. One... |
30,798 | Deep venous thrombosis after radiofrequency ablation of greater saphenous vein: a word of caution. | Radiofrequency ablation (RFA) of the greater saphenous vein (GSV; "closure") is a relatively new option for treatment of venous reflux. However, our initial enthusiasm for this minimally invasive technique has been tempered by our preliminary experience with its potentially lethal complication, deep venous thrombosis (... |
30,799 | Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis. | Heparin cofactor II (HCII) is a hepatic serpin with significant antithrombin activity that has been implicated in coagulation, inflammation, atherosclerosis, and wound repair. Recent data obtained in mice lacking HCII suggest that this serpin might inhibit thrombosis in the arterial circulation. However, the clinical r... |
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