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30,900
Challenges in the prevention of venous thromboembolism in the elderly.
Aging itself is a risk factor for venous thromboembolism, and the prevalence in the elderly of additional risk factors (e.g. cancer, orthopedic surgery, immobility) increase its intrinsic risk. Many in the medical community are reluctant to prescribe anticoagulation (for primary and secondary prevention of venous throm...
30,901
Use of different D-dimer levels to exclude venous thromboembolism depending on clinical pretest probability.
Currently, the same D-dimer cut-off point is used to define a positive result for all patients with suspected venous thromboembolism, regardless of their pretest probability. However, use of a relatively high D-dimer cut-off point (lower sensitivity) for those with a low clinical pretest probability, and a low D-dimer ...
30,902
C-reactive protein gene polymorphisms and the risk of venous thromboembolism: a haplotype-based analysis.
C-reactive protein (CRP) is a risk predictor for future athero-thrombotic events, and its plasma concentration has a heritable component. CRP has also been suggested to play a role in the pathophysiology of venous thromboembolism. To date, no genetic-epidemiological data are available on the relation of CRP gene varian...
30,903
Upper extremity deep vein thrombosis: clinical and treatment characteristics.
We aimed to evaluate patients with upper extremity deep vein thrombosis (UEDVT) in terms of the risk factors, symptoms, clinical course, diagnostic approaches and treatment outcome. Thirty-six patients with a diagnosis of UEDVT, comprising 19 males (52.7%) and 17 females (47.3%), were included in the study; the mean (+...
30,904
Superiority of fondaparinux over enoxaparin in preventing venous thromboembolism in major orthopedic surgery using different efficacy end points.
To assess the relevance of various efficacy end points established for thromboprophylaxis trials, we compared the results of the fondaparinux phase III program in major orthopedic surgery using the original primary efficacy end point with those obtained when the efficacy end points recently suggested by the American Co...
30,905
Radial optic neurotomy in the porcine eye without retinal vein occlusion.
To demonstrate the histopathologic changes in the porcine eye without retinal vein occlusion after radial optic neurotomy (RON).</AbstractText>A RON was performed in 14 normal eyes of 12 Yorkshire Cross pigs. One radial stab incision at the edge of the nasal optic nerve head was made using a 20-gauge microvitreoretinal...
30,906
Orbital venous malformations: current multidisciplinary treatment approach.
To evaluate the clinical, radiological, and histopathological features, treatment, and outcome of a series of orbital venous flow malformations (OVMs) with the aim of delineating a more systematic approach for treatment.</AbstractText>A 38-year retrospective review of 22 patients with OVMs followed up at 1 institute.</...
30,907
Intravitreal triamcinolone for the management of macular edema due to nonischemic central retinal vein occlusion.
To evaluate the efficacy of intravitreal triamcinolone acetonide in the management of persistent macular edema secondary to nonischemic central retinal vein occlusion (CRVO).</AbstractText>Twenty consecutive patients were selected with a 3- to 4-month history of nonischemic CRVO and persistent macular edema. These pati...
30,908
Intravitreal triamcinolone for the treatment of macular edema associated with central retinal vein occlusion.
To investigate the safety and efficacy of intravitreal triamcinolone acetonide as treatment for macular edema associated with central retinal vein occlusion (CRVO).</AbstractText>We reviewed the medical records of 13 consecutive patients (13 eyes) with macular edema associated with CRVO who were treated with an injecti...
30,909
Outcomes and cost of deep venous thrombosis among patients with cancer.
Although deep venous thrombosis (DVT) often complicates the clinical course in patients with cancer, few studies of the outcomes of DVT in this population have been published. Furthermore, the cost of DVT is largely undescribed. We herein report the largest study of DVT in this population to date.</AbstractText>We revi...
30,910
Short-term menopausal hormone therapy for symptom relief: an updated decision model.
Hormone therapy (HT) provides the most effective relief of menopausal symptoms. This therapy is associated with a decreased risk of osteoporosis and colorectal cancer but increased risks of cardiovascular disease (CVD), venous thrombosis, and breast cancer. Our objective was to identify which women should benefit from ...
30,911
Analysis of deep vein thrombosis in burn patients.
Deep vein thrombosis (DVT) represents a major cause of morbidity in surgical patients. Controversial reports exist on the incidence of DVT in burn patients. We report our experience over a 10-year period.</AbstractText>Patients admitted to our Burn Unit over the period 1991-2001 and diagnosed with DVT were identified. ...
30,912
Acute pulmonary embolism.
Deep vein thrombosis (DVT) and, therefore, pulmonary embolism (PE) are often preventable. Because of the lack of specificity of symptoms and signs, DVT and PE are frequently clinically unsuspected, leading to substantial diagnostic and therapeutic delays and resulting in considerable morbidity and mortality. Furthermor...
30,913
Ultrasound diagnosis of deep venous thrombosis.
The ultrasound diagnosis of deep venous thrombosis by an emergency physician is occurring with increased frequency. The examination is simple to perform and, when combined with a clinical pretest probability or D-dimer, can aid in the rapid disposition ofa patient with lower extremity pain and swelling. The technique a...
30,914
Renal ultrasound.
Renal US is one of several imaging modalities available to the EP in the evaluation of patients with acute urologic disorders. It offers excellent anatomic detail without exposure to radiation or contrast agents but is limited in its assessment of renal function. It is an important alternative to helical CT scanning fo...
30,915
New partially parallel acquisition technique in cerebral imaging: preliminary findings.
In MRI applications where short acquisition time is necessary, the increase of acquisition speed is often at the expense of image resolution and SNR. In such cases, the newly developed parallel acquisition techniques could provide images without mentioned limitations and in reasonably shortened measurement time. A newl...
30,916
Management of macular edema in branch retinal vein occlusion with sheathotomy and recombinant tissue plasminogen activator.
The common adventitial sheath that surrounds the retinal venule and arteriole at the crossing site plays a crucial role in branch retinal vein occlusion (BRVO). The purpose of this study was to report the surgical recanalization of the occluded vein using a bimanual technique and recombinant tissue plasminogen activato...
30,917
D-003 and warfarin interaction on the bleeding time and venous thrombosis experimentally induced in rats.
D-003 is a mixture of higher aliphatic primary acids isolated and purified from sugarcane wax, the main component of which is octacosanoic acid. D-003 exhibits a cholesterol-lowering effect as well as antiplatelet and antithrombotic effects in experimental models. Warfarin is a coumarin derivative with anticoagulant ac...
30,918
Randomized comparison of 6-mm straight grafts versus 6- to 8-mm tapered grafts for brachial-axillary dialysis access.
This report presents the results of a prospective randomized study that compared 2 grafts of different diameter: 6 mm, and 8 mm tapered to 6 mm at the arterial site, placed in the upper arm for hemodialysis in a selected population of patients younger than 71 years without diabetes.</AbstractText>Seventy consecutive pa...
30,919
A shortened activated partial thromboplastin time is associated with the risk of venous thromboembolism.
Hypercoagulability due to high coagulation factors XI, VIII, IX, II, and fibrinogen is recognized as a risk factor of venous thromboembolism (VTE). These factors are cumulatively explored by the activated partial thromboplastin time (APTT). To test the hypothesis that a short APTT increases the risk of VTE, a case-cont...
30,920
Bithalamic infarcts: embolism of the top of basilar artery or deep cerebral venous thrombosis?
Bithalamic infarcts are usually attributed to thromboembolism of the top of the basilar artery. However, in some cases, deep cerebral venous thrombosis and thrombosis of cerebral venous sinuses was proved to be the cause. The case of a 47-year-old female with ischemic thalamic and mesencephalic lesions is reported, tha...
30,921
Totally implantable femoral vein catheters in cancer patients.
Totally implantable devices are increasingly being utilized for chemotherapy treatment of oncological patients. When it is impossible to implant the reservoir on the anterior wall of the thorax, or when there is an obstruction of the superior vena cava system, alternative access routes must be sought. Of these, the fem...
30,922
Multiple-vein thrombosis and pulmonary embolism after pacemaker implantation treated by thrombolysis.
This report describes a patient who suffered multiple-vein thrombosis following permanent pacemaker implantation and developed a pulmonary embolism while on anticoagulation treatment, which was successfully treated by thrombolytic therapy.
30,923
Bilateral renal infarctions and lower limbs artery thrombosis in a patient with nephrotic syndrome.
Thromboembolism is a well-recognized complication in patients with nephrotic syndrome owing to their hypercoagulable status. Usually, the venous system is affected, whereas the very rare occurrence of arterial thrombosis is mainly restricted to pediatric patients. This complication often results in high rates of mortal...
30,924
Recurrence of hepatocellular carcinoma 102 months after successful eradication and removal of membranous obstruction of the inferior vena cava.
We report a 54-year-old Japanese woman who developed liver tumors 102 months after hepatic resection for hepatocellular carcinoma (HCC) and percutaneous transluminal angioplasty (PTA) for membranous obstruction of the inferior vena cava (MOVC), which is one form of Budd-Chiari syndrome. In the present admission workup ...
30,925
Lupus anticoagulant, factor V Leiden, and methylenetetrahydrofolate reductase gene mutation in a lupus patient with cerebral venous thrombosis.
We describe the case of a young Lebanese woman with systemic lupus erythematosus (SLE) and a positive lupus anticoagulant (LAC) who developed right internal jugular vein and sigmoid sinus thrombosis. Coagulation studies showed that in addition to the LAC the patient was heterozygous for the factor V (FV) Leiden mutatio...
30,926
[Venous thromboembolism prophylaxis].
Venous thromboembolism is a common and frequent complication of hospitalized patients. Some venous thromboembolisms may be subclinical, while others present as symptomatic deep vein thrombosis and/or pulmonary embolism. Venous thromboembolism and pulmonary embolism contribute significantly to inhospital morbidity and m...
30,927
Antiphospholipid syndrome and asymptomatic carriers of antiphospholipid antibody: prospective analysis of 404 individuals.
We carried out a prospective analysis of clinical and analytical findings in individuals with antiphospholipid antibodies (aPL).</AbstractText>We prospectively studied 404 individuals, classified in 2 groups: (1) patients with primary or secondary antiphospholipid syndrome (APS, n = 226); and (2) asymptomatic carriers ...
30,928
Utilization of CT-PA in an emergency department with readily available V/Q scintigraphy.
To describe the role of computed tomographic pulmonary angiography (CT-PA) in the emergency department of an institution which utilizes ventilation-perfusion (V/Q) scintigraphy as its primary imaging modality for the diagnosis of pulmonary embolism.</AbstractText>We retrospectively identified and reviewed the records o...
30,929
Pulmonary embolism-the initial manifestation of renal cell carcinoma in a young woman.
We report a case of massive pulmonary embolus demonstrated on CT in a young woman presenting with dyspnea, with no known risk factors for embolism. Abdominal CT on further investigation showed a renal tumor invading the left renal vein and the inferior vena cava as the cause of the pulmonary embolus. In a patient prese...
30,930
Changes in femoral vein blood flow velocity by intermittent pneumatic compression: calf compression device versus plantar-calf sequential compression device.
Intermittent pneumatic compression has become widely used to prevent deep venous thrombosis potentially causing fatal pulmonary embolism. Although uniform compression has been commonly applied, a new method of sequential compression from plantar to calf has recently been developed. In this report, changes in maximum bl...
30,931
Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients.
Considerable variability exists in the use of pharmacological thromboprophylaxis among acutely ill medical patients, partly because clinically relevant end points have not been fully assessed in this population. We undertook an international, multicenter, randomized, double-blind, placebo-controlled trial using clinica...
30,932
Unusual and aggressive thrombotic onset in two children with antiphospholipid-antibody syndrome and systemic lupus erythematosus.
We report two pediatric patients with unusual, aggressive initial manifestation of antiphospholipid antibody syndrome secondary to systemic lupus erythematosus. The first patient, a 13-year-old girl, presented with bilateral amaurosis and ischemic cerebral lesions. The second, another 13-year-old girl, presented with c...
30,933
Anomaly of the inferior vena cava causing recurrent deep vein thrombosis in a young male.
Anomaly of the inferior vena cava (IVC) as a cause of (recurrent) deep vein thrombosis (DVT) is uncommon. We report on a 33-year-old patient suffering from this unusual cause of DVT without the presence of known predisposing factors (immobilization, trauma, surgery, or underlying thrombophilia). Thus, in young patients...
30,934
Acute mesenteric venous thrombosis: a better outcome achieved through improved imaging techniques and a changed policy of clinical management.
To analyse and compare the results obtained from acute mesenteric venous thrombosis (MVT) patients before and after the change of the clinical management principle, to assess the factors responsible for the recent better outcome and determine the best management for this disease.</AbstractText>We retrospectively review...
30,935
Idiopathic intracranial hypertension: priapism of the brain?
It has long been recognized that a clinical syndrome similar to idiopathic intracranial hypertension can occur secondary to venous sinus obstruction with the elevation in sinus pressure causing a reversal in the pressure gradient across the arachnoid granulations and therefore elevated CSF pressure. There remains, howe...
30,936
The poor man's epidural: systemic local anesthetics for improving postoperative outcomes.
The inflammatory response is an important determinant of outcome after major surgery. Perioperative excessive stimulation of the inflammatory and hemostatic systems plays a role in the development of postoperative ileus, ischemia-reperfusion syndromes (e.g. myocardial infarction), hypercoagulation syndromes (e.g. deep ...
30,937
Activated protein C levels in Beh&#xe7;et's disease and risk of venous thrombosis.
Beh&#xe7;et's disease is a multi-systemic inflammatory disorder of unknown cause. Most abnormalities have been associated with endothelial injury caused by vasculitis. Thrombosis occurs in about 25% of patients, although the mechanism is unknown. The objective of this study was to evaluate the protein C activation syst...
30,938
Hormones and pregnancy: thromboembolic risks for women.
During their lifetimes, women face several unique situations with an increased risk of venous thromboembolism (VTE). Doctors in a variety of specialties must advise women on the risks of oral contraceptives (OC), hormone replacement or pregnancy. Modern 'low dose' OC are associated with a three to sixfold increased rel...
30,939
Insertion of prolonged venous access device: a comparison between surgical cutdown and percutaneous techniques.
The use of totally implantable prolonged venous access devices (TIPVAD) in chemotherapy for oncological patients is now consolidated practice, whereas the choice between surgical cutdown and the percutaneous technique is still a controversial matter. The aim of this study was to retrospectively evaluate the validity an...
30,940
Transcatheter arterial embolization for advanced tumor thrombus with marked arterioportal or arteriovenous shunt complicating hepatocellular carcinoma.
To evaluate the efficacy and safety of transcatheter arterial embolization with gelatin sponge immersed in an anti-cancer agent (GIA-TAE) alone or combined with radiation therapy, in hepatocellular carcinoma with portal vein tumor thrombus (PVTT) or hepatic vein tumor thrombus (HVTT) complicated by marked arterioportal...
30,941
[Thalidomide treatment of patients with refractory myeloma in the institutes participating in the Japan Myeloma Study Group].
Thalidomide was used in 73 patients with refractory myeloma in 15 of 45 institutes participating in the Japan Myeloma Study Group. The mean age and male/female ratio were 63.8 years and 0.92 (35/38), respectively. Thirty-four patients (47%) were treated with only thalidomide, 27 patients (37%) were treated with thalido...
30,942
Do thigh tourniquets contribute to the formation of intra-operative venous emboli?
The authors undertook a randomised prospective study to investigate the contribution of thigh tourniquets to the formation of intra-operative venous emboli during lower limb surgery. Patients were randomised to have a thigh tourniquet or no tourniquet and transoesophageal echocardiography was used to detect embolic sig...
30,943
Long-term prognosis of cerebral venous sinus thrombosis in childhood.
Cerebral venous sinus thrombosis (CVST) is a rare but potentially serious disorder in children. There is no literature on the long-term neuropsychological and emotional sequelae and implications for quality of life. We studied 17 children who had CVST after the neonatal period, aged between 1 month and 16 years at the ...
30,944
Low molecular weight heparin for the prevention of venous thromboembolism after abdominal surgery.
Abdominal surgery carries a significant risk of venous thrombosis, a risk further increased in patients with cancer.</AbstractText>Embase and Pubmed searches between 1980 and 2003, using the key words 'heparin,' 'surgery,' 'abdominal or rectal or colorectal or rectum or colon' and 'clinical trial', were conducted to id...
30,945
[Adventitial sheathotomy in branch retinal vein occlusion with non ischemic macular edema].
To determine whether surgical decompression of branch retinal vein occlusion at the arterio-venous (A/V) crossing is effective as a treatment for associated non ischemic macular edema.</AbstractText>A total of 13 consecutive patients with non ischemic macular edema secondary to branch retinal vein occlusion were treate...
30,946
Heparin-induced thrombocytopenia and vascular surgery.
Heparin-induced thrombocytopenia (HIT) is of special interest to vascular surgeons as heparin is the predominant anticoagulant used before, during, and after vascular surgery. Further, the prothrombotic nature of this antibody-mediated disorder leads to a high frequency of limb ischemia due to large arterial occlusion ...
30,947
Central venous catheters: choosing the most appropriate access route.
Intravenous therapy and care is a complex and intricate area of practice, which is being subsumed into the core role of registered nurses. As more patients become recipients of a vascular access device (VAD), particularly those requiring intermediate to long-term central venous access, it is important to ensure that no...
30,948
Real-time intravascular ultrasound-guided placement of a removable inferior vena cava filter.
Reports have demonstrated the benefit of prophylactic inferior vena cava filter (IVCF) placement to prevent pulmonary embolism. This series evaluates the potential for the bedside placement of a removable IVCF under "real-time" intravascular ultrasound (IVUS) guidance.</AbstractText>Twenty trauma patients underwent int...
30,949
[Sinistral portal hypertension with bleeding gastric varices as initial manifestation of renal-cell carcinoma].
We report a clinic case of renal-cell carcinoma presenting as sinistral portal hypertension; a clinical syndrome consisting of esplenic vein thrombosis manifested as isolated gastric varices with patent portal vein and normal hepatic function. The most frequent cause of this syndrome is pancreatic pathology. Renal-cell...
30,950
Diagnosis of lower-extremity deep vein thrombosis in outpatients with musculoskeletal disorders: a national survey study of physical therapists.
Prompt identification of outpatients who may have proximal lower-extremity deep vein thrombosis (PDVT) is important, in part, because of the risk of pulmonary embolism. The purposes of our study were to determine the degree of accuracy of physical therapists' estimates of the probability of PDVT in hypothetical patient...
30,951
[Combined video-thoracoscopic, surgical and endovascular treatment in a case of ascites and recurrent bilateral pleural effusion].
Among recurrent pleural effusions a role of remarkable importance is held by those combined with ascitis due to the difficulty of their treatment, even using widely tested techniques. The incidence of such pathology varies from 4% to 6% of patients suffering from cirrhotic pathology, reaching 10% in cases with advanced...
30,952
[Right atrial thrombus--a complication of central venous catheters].
We describe the development, in three days, of a pediculate mass hanging on the right atrial lateral wall in a 39-year-old woman with a subclavian venous catheterization. She was a current smoker and alcoholic but without drug addict. The hypothesis of a non valvular right atrial infective endocarditis was considered a...
30,953
High prevalence of anti-prothrombin antibody in patients with deep vein thrombosis.
The present study was designed to determine the prevalence of lupus anticoagulant (LA) antibody and several antibodies for antiphospholipid syndrome (APS) in patients with deep vein thrombosis (DVT)/pulmonary embolism (PE) (n = 48), cerebral thrombosis (CT, n = 30), systemic lupus erythematosus (SLE, n = 22), and idiop...
30,954
Primary upper-extremity deep vein thrombosis: high prevalence of thrombophilic defects.
Primary deep venous thrombosis of the upper extremity (UEDVT) is an unusual disorder. Limited data are available on the contribution of hypercoagulable status in the pathogenesis of this disease. This study aims to report the prevalence of inherited and acquired thrombophilic risk factors (TF) in patients with primary ...
30,955
An overview of the heparin-induced thrombocytopenia syndrome.
Heparin-induced thrombocytopenia (HIT) is caused by heparin-dependent, platelet-activating IgG antibodies that increase thrombin generation in vivo, producing a prothrombotic phenotype. In addition to platelet activation, there is in vitro evidence that activation of endothelium and monocytes occurs, perhaps directly b...
30,956
[Risk factors and clinical characteristics of thromboembolic venous disease in young patients: a prospective study].
We aimed to determine the risk factors of thromboembolic disease in young patients and to study the clinical characteristics according to the etiology.</AbstractText>A prospective study of 100 patients under 50 years who were not affected by neoplasias or chronic diseases and who required hospitalization due to thrombo...
30,957
Combined central retinal artery and vein occlusion from orbital inflammatory pseudotumour.
Progressive, painful blurred vision and proptosis developed in the left eye of a 32-year-old man over an 8-day period. On initial neuro-ophthalmic evaluation the visual acuity in the left eye was no light perception. Erythema of the periorbital skin, 5 mm of proptosis, and ophthalmoplegia were noted on the left side. F...
30,958
Thrombotic complications of implanted central venous access devices: prospective evaluation.
Implanted venous access devices (IVAD) are routinely used in oncologic patients. Thrombotic complication is a source of morbidity. During one year 246 patients with different solid neoplastic diseases received IVAD for chemotherapy administration. Two hundred forty-nine IVAD were placed percutaneously or by surgical cu...
30,959
Fatal venous thromboembolism associated with antipsychotic therapy.
To describe the occurrence of pulmonary embolism (PE) as a rare adverse effect of clozapine that is treatable, but sometimes fatal, and survey the literature on the subject in the hope of increasing awareness of the potential danger that may result from drug interactions.</AbstractText>A 47-year-old woman treated with ...
30,960
Mouse cremaster venules are predisposed to light/dye-induced thrombosis independent of wall shear rate, CD18, ICAM-1, or P-selectin.
Microvascular adhesion of platelets to endothelium occurs in response to various inflammatory stimuli, and in venules is often accompanied by adherent leukocytes. In a light/dye injury model, platelet adhesion and thrombi occur preferentially in venules, though the reasons for this predisposition are unknown. The autho...
30,961
Systemic haemostasis after intermittent pneumatic compression. Clues for the investigation of DVT prophylaxis and travellers thrombosis.
Intermittent pneumatic compression (IPC) is known to provide effective prophylaxis against post-surgical deep-vein thrombosis (DVT), and other procedures based on reducing venous stasis have been promoted recently to minimize the risk of thromboembolism after long-haul travel ('travellers thrombosis'). This study sough...
30,962
[Axial length and branch retinal vein occlusion].
To determine whether there is a connection between the axial length and the occurrence of the branch retinal vein occlusion (BRVO).</AbstractText>18 patients that had been diagnosed with BRVO have been selected retrospectively. The diagnosis has been made according to the clinical criteria (fundus aspect). A control gr...
30,963
Treatment of superior mesenteric and portal vein thrombosis with direct thrombolytic infusion via an operatively placed mesenteric catheter.
Acute superior mesenteric vein (SMV) and portal vein (PV) thrombosis can be a complication of hypercoagulable, inflammatory, or infectious states. It can also occur as a complication of medical or surgical intervention. Management of mesenteric and portal vein thrombosis includes both operative and nonoperative approac...
30,964
Paroxysmal nocturnal hemoglobinuria in a girl with hemolysis and "hematuria".
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder of unknown frequency. In its classic form, PNH is characterized by hemolysis accompanied by nocturnal hemoglobinuria. The clinical course is unpredictable and may vary from severe hemolysis and recurrent venous thrombosis to latent periods with milder symptom...
30,965
Prothrombin G20210A gene mutation with LightCycler polymerase chain reaction in venous thrombosis and healthy population in the southeast of Turkey.
Venous thrombosis (VT) is a common disease, with an annual incidence in the general population of approximately 1 per 1000. The prevalence of genetic risk factors for thrombosis varies greatly in different parts of the world. Prothrombin G20210A (PT G20210A) gene mutation has been recently identified as a common risk f...
30,966
[Heparin induced thrombocytopenia. A frequently unrecognised complication after major orthopedic surgery].
The application of unfractioned (UFH) and low molecular weight heparins (LMH) has reduced the incidence of thromboembolic events. However, the frequency of heparin-induced thrombocytopenia (HIT II) in orthopedic patients, particularly susceptible for both thromboembolic complications and HIT II with potentially life th...
30,967
Twenty-one-year trends in the use of inferior vena cava filters.
Improved inferior vena cava (IVC) filters have led to liberalization of the indications for insertion. Increased use, however, has been followed with a potential for unwarranted insertion. There are only sparse data on trends in the use of IVC filters in patients with pulmonary embolism (PE), patients with deep venous ...
30,968
Paediatric pulmonary vascular disease.
Pulmonary vascular disease comprises any congenital or acquired pathology of the intrinsic pulmonary vessels with the unique feature of pulmonary arteries carrying unsaturated blood and pulmonary veins carrying oxygenated blood. Pulmonary hypertension (PH) ensues when pulmonary vascular disease affects at least 50% of ...
30,969
Portosystemic shunts in children: a 15-year experience.
The role of portosystemic shunt (PSS) in children with portal hypertension has changed because of acceptance of liver transplantation and endoscopic hemostasis. We report our experience with PSS, mainly the distal splenorenal shunt, to define its role in the management of variceal bleeding.</AbstractText>From 1987 to 2...
30,970
Mechanical prophylaxis of deep-vein thrombosis after total hip replacement a randomised clinical trial.
Routine prophylaxis for venous thromboembolic disease after total hip replacement (THR) is recommended. Pneumatic compression with foot pumps seems to provide an alternative to chemical agents. However, the overall number of patients investigated in randomised clinical trials has been too small to draw evidence-based c...
30,971
Effect of the two-wall-stitch mistake upon patency of rat femoral vein anastomosis: Preliminary observations.
Anastomotic patency is believed to be the most important factor in microvascular surgery. The two-wall stitch is a technical error commonly considered to cause thrombosis of the anastomosis, especially on the venous side. In order to demonstrate the real effect on vein patency of the two-wall stitch, the authors perfor...
30,972
Salvage of free flaps after venous thrombosis: case report.
Venous thrombosis of a free flap is a serious complication in microsurgery. Several agents with the ability to dissolve an occluding thrombus exist. Recombinant tissue plasminogen activator (rt-PA) seems the most effective. We present our experience with a procedure that was successful in elimination of the occluding t...
30,973
Role of ulnar forearm free flap in oromandibular reconstruction.
The ulnar forearm flap is not frequently utilized for oromandibular reconstruction. This study evaluated the usefulness of the ulnar free flap for reconstruction. A retrospective study of 32 patients was conducted. The ulnar forearm flap was combined with an osseous flap in 24 patients. Nine females and 23 males with a...
30,974
The risk of venous thromboembolic disease associated with adjuvant hormone therapy for breast carcinoma: a systematic review.
Tamoxifen therapy for patients with breast carcinoma is perceived as an independent risk factor for venous thromboembolic events (VTE), but the risk associated with other adjuvant therapies is less well recognized.</AbstractText>The authors conducted a computerized PubMed literature search for English-language articles...
30,975
Importance of anatomical asymmetries of transverse sinuses: an MR venographic study.
Time-of-flight (TOF) magnetic resonance venography (MRV) is often used to examine the intracranial dural sinuses, particularly in the evaluation of dural sinus thrombosis. The goal of the study was to evaluate the use of TOF MRV in assessing the normal anatomy of dural sinuses and their variations as sources of potenti...
30,976
Safety and efficacy of single bolus anticoagulation with enoxaparin for chronic hemodialysis. Results of an open-label post-certification study.
Low-molecular-weight heparin (LMWH) is supposed to be advantageous compared to unfractionated heparin for chronic hemodialysis (HD) with respect to lipid and bone metabolism, polymorphonuclear cell stimulation, induction of antibody-mediated thrombocytopenia, and aldosterone suppression. Due to longer biological half-l...
30,977
A negative personal and family history for venous thrombotic events is not sufficient to exclude thrombophilia in patients with cerebral venous thrombosis.
A hereditary thrombophilia is found in 20-30% of patients with cerebral venous thrombosis (CVT). These patients might have an increased rate of a positive personal or family history of venous thrombotic events. We investigated the diagnostic value of a structured personal and family history for venous thrombotic events...
30,978
A contemporary evaluation of cytoreductive nephrectomy with tumor thrombus: Morbidity and long-term survival.
Metastatic renal cell carcinoma (RCC) is an aggressive entity that frequently invades the venous system. We evaluated the morbidity and survival of patients with tumor thrombus who undergo cytoreductive nephrectomy.</AbstractText>We identified 56 patients from our institution's database who had a primary renal tumor in...
30,979
Risk factors for deep vein thrombosis in inpatients aged 65 and older: a case-control multicenter study.
To identify independent risk factors of symptomatic deep vein thrombosis (DVT) in geriatric inpatients and to define high-risk patients likely to benefit from preventive treatment.</AbstractText>Hospital-based case-control multicenter study with prospective data collection.</AbstractText>Geriatric university hospitals ...
30,980
Ximelagatran, a new oral direct thrombin inhibitor, for the prevention of venous thromboembolic events in major elective orthopaedic surgery. Efficacy, safety and anaesthetic considerations.
The oral direct thrombin inhibitor ximelagatran shows great promise for prevention of venous thromboembolic events following major elective orthopaedic surgery. Its consistent and predictable pharmacokinetics and pharmacodynamics across a wide range of patient populations allow administration with fixed dosing and with...
30,981
Right versus left internal jugular vein catheterization for hemodialysis: complications and impact on ipsilateral access creation.
This study investigated whether the anatomical differences between right and left internal jugular vein catheterization (RJVC and LJVC) would lead to differences in the frequency of complications, in particular, central vein occlusion (CVO). A group of 479 jugular vein catheterizations, 403 RJVC and 77 LJVC done in 294...
30,982
Sinusoidal dilatation and congestion in liver biopsy: is it always due to venous outflow impairment?
Impairment of venous outflow manifests as zone 3 sinusoidal dilatation and congestion (SDC) in liver biopsy. However, the finding of SDC is not specific for venous outflow impairment.Objectives.-To determine the specificity of SDC in liver biopsies for venous outflow impairment and to seek an explanation for SDC in pat...
30,983
Under-reporting of serious adverse drug reactions in Sweden.
Adverse drug reactions (ADR) constitute a major problem, both from a medical point of view and as an economical burden. Spontaneous reporting of ADRs is one of the methods for post marketing surveillance of drug safety. Under-reporting can also provide an important obstacle to rapid and relevant signal detection.</Abst...
30,984
Venous thromboembolism associated with cyproterone acetate in combination with ethinyloestradiol (Dianette): observational studies using the UK General Practice Research Database.
To derive risk estimates for venous thromboembolism (VTE) in women prescribed cyproterone acetate combined with ethinyloestradiol (CPA/EE), a drug licensed in the UK for the treatment of women with acne or hirsutism. CPA/EE provides a treatment option for women with polycystic ovary syndrome (PCOS). CPA/EE has been ass...
30,985
Postmenopausal hormone replacement and venous thromboembolism following hip and knee arthroplasty.
Hormone replacement therapy has been associated with venous thromboembolism. Controversy exists regarding the appropriate management of hormone replacement in the perioperative setting and in other situations--such as acute illness--predisposing to acute venous thromboembolism. We performed a case-control study to dete...
30,986
Incidence of post-thrombotic syndrome and its association with various risk factors in a cohort of Spanish patients after one year of follow-up following acute deep venous thrombosis.
Post-thrombotic syndrome (PTS) is a frequent complication of deep venous thrombosis (DVT). However, neither the incidence nor the moment of PTS appearance are known. The main reason are the criteria used to define PTS, the characteristics of the patients, the study design and the time of follow-up. Our aims were to est...
30,987
Thrombotic complications in patients with hereditary bleeding disorders.
Thromboses in patients with hereditary bleeding disorders are uncommon. However, in some cases, the co-existence of prothrombotic risk factors may increase the likelihood of developing thrombotic complications in such patients. This review summarizes the cases of thrombosis reported in the literature and analyzes the m...
30,988
Alterations in hepatic uptake and distribution of organ-specific superparamagnetic MRI contrast media: clinical findings and classification according to pathogenesis.
The aim of this study was to classify the alterations in the liver uptake and distribution of superparamagnetic contrast media that could potentially lead to diagnostic errors. These alterations, referred to as SPIO-LUDA for convenience, may be caused by a variety of disorders, such as cirrhosis, vascular thrombosis, h...
30,989
Relationship between various patterns of transient increased hepatic attenuation on CT and portal vein thrombosis related to acute cholecystitis.
We sought to investigate the prevalence of portal vein thrombosis in patients with acute cholecystitis and the relationship between portal vein thrombosis and the various patterns of transient increased hepatic attenuation on CT.</AbstractText>We studied 72 of 107 patients with acute cholecystitis who, during a 3-year ...
30,990
Design, synthesis, and biological activity of potent and selective inhibitors of blood coagulation factor Xa.
Factor Xa (FXa) has materialized as a key enzyme for the intervention of the blood coagulation cascade and for the development of new antithrombotic agents. FXa is the lone enzyme responsible for the production of thrombin and therefore is an attractive target for the control of thrombus formation. We have designed and...
30,991
Primary antiphospholipid antibody syndrome presenting as venous infarct and deep vein thrombosis.
We report the case of a young lady with primary antiphospholipid antibody syndrome, who had two spontaneous abortions and cerebral venous thrombosis and subsequently deep vein thrombosis of the leg veins. Three classes of antiphospholipid antibodies (IgG, IgM, IgA) were elevated. There was no clinical or laboratory evi...
30,992
Acute superior mesenteric vein thrombosis associated with factor V 'Leiden' gene mutation.<Pagination><StartPage>611</StartPage><EndPage>613</EndPage><MedlinePgn>611-3</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To study thrombophilia states in Indian patients with acute ...
To study thrombophilia states in Indian patients with acute spontaneous superior mesenteric vein thrombosis (SMVT).</AbstractText>Two men with this condition, a 56 year old and a 31 year old presenting with acute SMVT, demonstrated on CT scan, were subjected to a thrombophilia screen consisting of Protein C, S, antithr...
30,993
Diagnosis of infection of implantable central venous catheters by [18F]fluorodeoxyglucose positron emission tomography.
The aim of this study was to evaluate the role of [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging in the diagnosis of infection of implantable vascular catheters.</AbstractText>We evaluated six patients with haematological cancer and infection of their implantable vascular catheter and who unde...
30,994
Neurological conditions at altitude that fall outside the usual definition of altitude sickness.
Altitude sickness in its commonly recognized forms consists of acute mountain sickness and the two life-threatening forms, high altitude cerebral and pulmonary edema. Less well known are other conditions, chiefly neurological, that may arise completely outside the usual definition of altitude sickness. These, often foc...
30,995
Low molecular weight heparins: the optimal treatment for venous thromboembolism.
Venous thromboembolism (VTE) is a common vascular complication that requires immediate as well as long-term treatment. Unfractionated heparin (UFH), followed by oral anticoagulants (OAs), is of proved efficacy in the treatment of deep venous thrombosis (DVT) and pulmonary embolism (PE). However, low molecular weight he...
30,996
Liver retransplantation in an infant requiring cavoportal hemi transposition.
Historically inability to achieve portal inflow to the liver allograft operatively was felt to be a contraindication to orthotopic liver transplantation (OLTx). Cavoportal hemi transposition has been utilized more recently in adult OLTx recipients but rarely in pediatric recipients. Here we report the case of a 10-mont...
30,997
Thromboprophylaxis for radical prostatectomy: a comparative analysis of present practice between the USA, the UK, and Ireland.
A clinical dilemma exists in the management of patients undergoing radical prostatectomy (RP) whereby measures taken to reduce the risk of thrombotic events may adversely affect efforts to limit blood loss. No consensus exists in the literature on the ideal management of thromboprophylaxis in these patients. Our aim is...
30,998
Growth assessment in children with extra-hepatic portal vein obstruction and portal hypertension.
Several studies carried out to examine the growth of children with extra-hepatic portal vein obstruction and portal hypertension have reported a variety of findings.</AbstractText>To assess anthropometric indices in children with portal hypertension due to extra-hepatic portal vein obstruction and who were treated by e...
30,999
Risk factors and recurrence rate of primary deep vein thrombosis of the upper extremities.
One third of cases of upper-extremity deep vein thrombosis (DVT) are primary, ie, they occur in the absence of central venous catheters or cancer. Risk factors for primary upper-extremity DVT are not well established, and the recurrence rate is unknown.</AbstractText>We studied 115 primary upper-extremity DVT patients ...