Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
30,800 | Spontaneous regression of cerebral AVM due to thrombosis of draining vein--angiographic and MRI demonstration. | Spontaneous regression of cerebral arteriovenous malformation (AVM) is rare and poorly understood phenomenon. We present a case of spontaneous complete and asymptomatic occlusion of the AVM associated with thrombosis of the draining cortical vein. The thrombosed draining cortical vein is beautifully demonstrated on mag... |
30,801 | Traumatic unilateral deep cerebral venous infarction. | A case of unilateral deep cerebral venous infarction in a young man associated with mild head injury is presented. The diagnosis is made on the basis of the clinical, radiological, operative and histopathological findings. We propose that a thrombosis or obstruction of the anterior segment of the basal vein of Rosentha... |
30,802 | Management patterns and outcomes of patients with venous thromboembolism in the usual community practice setting. | The objectives of this study were to observe a commercially insured sample diagnosed with a venous thromboembolism (VTE) event and treated postevent with warfarin and to detail the thromboembolic and bleeding outcomes in the time periods during warfarin therapy and after discontinuation of such therapy.</AbstractText>T... |
30,803 | Management of thalidomide toxicity. | Thalidomide has re-emerged as a novel antineoplastic agent with immunomodulatory and antiangiogenic activities. In the early sixties, it was withdrawn from the market after its infamous association with congenital abnormalities that left about 10,000 children affected world-wide. With strict regulations and precautions... |
30,804 | Management of thrombosis in the cancer patient. | The treatment of venous thromboembolism in the cancer patient presents many challenges. The safety and efficacy of anticoagulation in these patients are still evolving. The clinical scenario is often unique to each patient and dictates careful consideration of the method of anticoagulation. Various issues that need to ... |
30,805 | Economics of unfractionated heparin: beyond acquisition cost. | Despite numerous clinical trials demonstrating advantages of new anticoagulants, unfractionated heparin (UFH) is still used by a number of clinicians in the United States. The reason for this continued use of UFH is not superior efficacy, improved safety, or convenience, but low acquisition cost. However, several other... |
30,806 | Unfractionated heparin dosing nomograms: road maps to where? | Weight-adjusted nomograms have been a significant advance in the use of unfractionated heparin (UFH). Clinical trials have demonstrated the ability of weight-adjusted nomograms to achieve a therapeutic activated partial thromboplastin time (aPTT) more rapidly than with standard UFH dosing. Despite this advantage, a sig... |
30,807 | Treatment of venous thromboembolism: challenging the unfractionated heparin standard. | Venous thromboembolism (VTE) is a major public health problem leading to high morbidity and mortality in the United States. Since more then 50% of patients with VTE may have asymptomatic disease, the start of appropriate therapy often is delayed. Traditionally, intravenous unfractionated heparin (UFH) has been used to ... |
30,808 | Anticoagulant prophylaxis in medical patients: an objective assessment. | Venous thromboembolism (VTE) is a clinically silent and potentially fatal disease that manifests as deep vein thrombosis (DVT) and pulmonary embolism. Venous thromboembolism remains a serious public health challenge, with an ever-increasing odds ratio of occurrence given the aging population in the United States. This ... |
30,809 | Heparin overview and issues. | Unfractionated heparin (UFH), which has been available commercially for over half a century, has been the most widely used agent for quickly suppressing thrombosis. When given intravenously, UFH quickly binds to and activates antithrombin, which then inhibits several activated factors in the clotting cascade. For decad... |
30,810 | High-pass-low-pass (HP-LP) reconstruction of CINE phase-contrast MRI. | A new interpretation of CINE phase-contrast (PC) MRI is presented in which flowing blood is shown to induce separate high- and low-temporal-frequency components in the resulting image sequence. The flow velocities can then be extracted from the ratio of these two components, independently of any unknown phase offset. T... |
30,811 | Lateral sinus thrombosis associated with zoster sine herpete. | Herpes zoster results from reactivation of the varicella zoster virus (VZV). Zoster sine herpete (ZSH) is an uncommon manifestation of VZV infection and presents with similar symptoms but without the vesicular rash. We describe an unusual case of lateral sinus thrombosis (LST) that developed during the clinical course ... |
30,812 | A case of antiphospholipid antibody syndrome with Budd-Chiari and colonic ulcers complicated with gastrointestinal hemorrhage. | The antiphospholipid antibody syndrome (APA) is characterized by an increased incidence of venous and arterial thrombosis. APA syndrome has some gastroenterological manifestations such as Budd-Chiari syndrome, hepatic infarction, esophageal necrosis, intestinal ischemia, pancreatitis and colonic ulceration. We report a... |
30,813 | Duodenal varices as an unusual cause of gastrointestinal bleeding due to portal hypertension: a case report. | Duodenal varices that develop in patients with portal hypertension rarely cause hemorrhage, but varix rupture is a serious and often fatal event. We report the case of a 38-year-old man with hepatic vein occlusion who was referred to our hospital for gastrointestinal hemorrhage of unknown origin. Upper gastrointestinal... |
30,814 | A case of Budd-Chiari syndrome secondary to multiple thrombogenic conditions: a case report and review of literature. | This report describes a case of Budd-Chiari syndrome caused by latent polycythemia vera and factor V Leiden mutation. This syndrome usually occurs due to thrombosis of hepatic veins or membranous obstruction of inferior vena cava. The most common reasons for thrombosis are manifest polycythemia vera and the other proth... |
30,815 | Cerebral venous sinus thrombosis as presenting feature of Crohn's disease. | Hepatobiliary and vascular manifestations are rare form of extraintestinal manifestations in Crohn's disease. We report a 20-year-old man in whom cerebral venous sinus thrombosis was the presenting symptom and preceded the diagnosis of Crohn's disease. |
30,816 | Impact of progestagens on activated protein C (APC) resistance among users of oral contraceptives. | Oral contraceptive (OC) use is associated with an increased risk of venous thromboembolism. Previous data reported higher thrombotic risk in women using third-generation combined OC than in those using second generation OC. The difference could be explained by differential effects of progestagens on plasma sensitivity ... |
30,817 | Correlation between thrombus regression and recurrent venous thromboembolism. Examining venographic and clinical effects of low-molecular-weight heparins: a meta-analysis. | We analyzed the correlation between thrombus regression on control venography performed after discontinuation of heparin therapy and recurrent venous thromboembolism (VTE) detected during clinical follow-up in randomized trials comparing low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) in patients w... |
30,818 | Dose escalating safety study of a new oral direct thrombin inhibitor, dabigatran etexilate, in patients undergoing total hip replacement: BISTRO I. | Dabigatran etexilate (BIBR 1048) is an oral direct thrombin inhibitor undergoing evaluation for the prevention of venous thromboembolism (VTE) following total hip replacement. Following oral administration, dabigatran etexilate is rapidly converted to its active form dabigatran (BIBR 953 ZW).</AbstractText>To determine... |
30,819 | Familial thrombophilia and lifetime risk of venous thrombosis. | We started a large multicenter prospective follow-up study to provide reliable risk estimates of venous thrombosis in families with various thrombophilic defects.</AbstractText>This paper describes data collected at study entry on venous events experienced before study inclusion, i.e. the baseline data.</AbstractText><... |
30,820 | [The importance of forseeing and early diagnosis of thromboembolic disease]. | The aim of this study is to assess the incidence of thromboembolism in laparoscopic cholecystectomies. 100 unselected patients undergoing laparoscopic procedures performed by the same team were studied. All patients received preoperative prophylaxis with low/molecular weight heparin (LMWH), which was continued until fu... |
30,821 | Thrombosis and anticoagulation in palliative care: an evolving clinical challenge. | There is a clear recognition of the relationship between thrombosis and neoplastic diseases. In recent years, there have been a few reports dealing with some of the features of clinical progression and management of venous thromboembolism (VTE) in palliative care patients. In this report, we present four cases that des... |
30,822 | Intravitreal preservative-free triamcinolone acetonide for the treatment of macular oedema. | To report the use of commercially available preservative-free intravitreal triamcinolone acetonide for the treatment of macular oedema due to retinal vascular diseases.</AbstractText>Retrospective interventional case series.</AbstractText>Charts of eyes that received 4 mg preservative-free intravitreal triamcinolone ac... |
30,823 | Is AV fistula patency associated with angiotensin-converting enzyme (ACE) polymorphism and ACE inhibitor intake? | <AbstractText Label="BACKGROUND/AIMS" NlmCategory="OBJECTIVE">Hemodialysis treatment requires a well-functioning vascular access. Access patency is limited by the development of venous intimal hyperplasia, which predisposes to fistula stenosis and subsequent thrombosis. In animal models, the renin-angiotensin system ha... |
30,824 | Incidence and etiologies of stroke during pregnancy and puerperium as evidenced in Taiwanese women. | Pregnancy is a known risk factor for stroke, but relatively few studies have been conducted in Asian populations to document the risk. This study aimed to analyze the incidence and etiologies of stroke occurring during pregnancy and puerperium in Taiwanese women.</AbstractText>From 1984 to 2002, female patients 15 thro... |
30,825 | Serum lipid levels and the risk of venous thrombosis. | Lipids, through effects on the coagulation and fibrinolytic systems, may contribute to the development of venous thrombosis. This association has been investigated in a few studies, with conflicting results.</AbstractText>We conducted a population-based, case-control study at a health maintenance organization in Washin... |
30,826 | Genetic thrombophilia. | The genetic thrombophilias are an important cause of venous thrombotic events. Much has been learned about the natural history of these disorders, their genetics, and, to a lesser degree, their treatment. This article provides an overview of the genetics of thrombophilia. Specific information on the factor V Leiden mut... |
30,827 | Sinus thrombosis after a jump from a small rock and a sneezing attack: minor endothelial trauma as a precipitating factor for cerebral venous thrombosis? | Cerebral venous thrombosis (CVT) associated with minor or trivial head trauma has only been described in a few cases so far. We report two patients who developed CVT after a sudden intracranial pressure increase and head acceleration. A 49-year-old woman jumped from a small rock, 1 m in height, and developed instantane... |
30,828 | Radiofrequency ablation combined with percutaneous ethanol injection in the treatment of hepatocellular carcinoma and portal vein neoplastic thrombosis. | In the last ten years new techniques, such as percutaneous ethanol injection (PEI) and radiofrequency ablation (RFA), have been developed for the treatment of hepatocellular carcinoma (HCC). Portal vein involvement is a complication of HCC and the role of surgical resection for HCC with tumor thrombi in the portal vein... |
30,829 | Medium-term results with a primary cemented rotating-hinge total knee replacement. A 7- to 15-year follow-up. | We reviewed 100 cemented Endo-model rotating-hinge (Waldemar Link GMBH & Co, Hamburg, Germany) total knee replacements in 80 patients with a mean age of 70 years (56 to 85) at a mean post-operative follow-up of 11 years (7 to 15). Good or excellent results were seen in 91% of knees and survival at 15 years was 96.1... |
30,830 | Prevention of deep-vein thrombosis after total hip and knee replacement. Low-molecular-weight heparin in combination with intermittent pneumatic compression. | After total hip (THR) or knee replacement (TKR), there is still an appreciable risk of developing deep-vein thrombosis despite prophylaxis with low-molecular-weight heparin (LMWH). In a prospective, randomised study we examined the efficacy of LMWH in combination with intermittent pneumatic compression in patients unde... |
30,831 | Behcet's disease: experience in a tertiary rheumatology centre in Singapore and a review of the literature. | The only reported study on Behcet's disease (BD) in Singapore found that only 15% of 34 BD patients managed at a tertiary dermatology centre had arthritis and 6% had eye complications with no other systemic manifestations. The aim of our study was to characterise the clinical manifestations and outcome of patients with... |
30,832 | Pharmacoeconomic analysis of bemiparin and enoxaparin as prophylaxis for venous thromboembolism in total knee replacement surgery. | Low molecular weight heparins are effective and have a good tolerability profile as first-line prophylaxis for venous thromboembolism (VTE) in major orthopaedic surgery. However, pharmacological inequivalence within the class could lead to differences in cost-effectiveness ratios.</AbstractText>To quantify the potentia... |
30,833 | Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation. | A group of 256 newly diagnosed myeloma patients were enrolled in a phase III study that included 4 monthly cycles of induction chemotherapy and tandem transplant. All patients were randomized to either receive or not receive thalidomide. A total of 221 patients (86%) received no prophylactic anticoagulation (cohort I);... |
30,834 | Thalidomide for the treatment of multiple myeloma. | Although thalidomide was withdrawn in the 1960s after its teratogenic property was recognized, it was subsequently found that this drug possesses immunomodulatory and anti-inflammatory effects. Recent studies have also demonstrated that thalidomide has antineoplastic activity via an antiangiogenic mechanism. Observatio... |
30,835 | Thrombophlebitis diagnosed on indium-111 labelled white cell scan. | A 64-year-old lady with type 2 diabetes and a non-resolving right foot ulcer, had an indium-111 labelled white cell scan (indium-111 WCS) to investigate the possibility of underlying osteitis. The scan suggested the possibility of infective thrombophlebitis. Unknown to the clinical team who requested the scan and the r... |
30,836 | Is there a role for TPN in terminally ill patients with bowel obstruction? | There is controversy regarding the use of total parenteral nutrition (TPN) in individuals with metastatic malignancies. The objective of this study was to determine whether a subgroup of patients with intestinal obstruction would benefit from support with TPN.</AbstractText>A retrospective review of patients considered... |
30,837 | Antibody to serum amyloid A. | Serum amyloid A (SAA) is elevated in inflammatory states. While antibodies to CRP, the other major acute phase reactant, have been described, to our knowledge, antibodies to SAA have not. This study was therefore undertaken to determine whether antibodies to SAA could be detected in patients and whether these antibodie... |
30,838 | Pentasaccharides. The new anticoagulants. | Venous thromboembolism VTE remains a common but preventable disease. The last decade has witnessed major advances in VTE treatment and prophylaxis. Low molecular weight heparins LMWH became the agents of choice in the treatment of deep venous thrombosis DVT and are increasingly used in the treatment of stable pulmonary... |
30,839 | Venous thromboembolism after acute ischemic stroke: a prospective study using magnetic resonance direct thrombus imaging. | We prospectively evaluated the prevalence and clinical risk factors for venous thromboembolism (VTE) after acute ischemic stroke using magnetic resonance direct thrombus imaging, a highly accurate noninvasive technique that directly visualizes thrombus.Method-102 unselected patients with AIS receiving standard prophyla... |
30,840 | Anesthetic management of a parturient with congenital cavernous transformation of the portal vein and chronic thrombocytopenia. | Cavernous transformation of the portal vein is a rare disorder resulting from extrahepatic portal vein thrombosis and development of collateral venous circulation. We report a case of a pregnant patient with congenital cavernous transformation of the portal vein associated with persistent consumptive coagulopathy and c... |
30,841 | Biochemical strategies to anticoagulation: a comparative overview. | Hypercoagulability is widely associated with sepsis, inflammation, diabetes, cancers, aging, and many pathological conditions, resulting in life-threatening disseminated intravascular coagulation (DIC), venous thrombosis, thromboembolism, cardiovascular complications, or even deadly multiple organ failure. Relieving co... |
30,842 | Cardiovascular alterations after spinal cord injury: an overview. | The recent developments in the management of spinal cord injury (SCI) have led to a reduction in mortality and in the consequences, resulting from incomplete spinal cord damage in those who survive. In this respect, it is noteworthy that SCI not only results in paraplegia or tetraplegia, but also in systemic, cardiovas... |
30,843 | Direct antithrombins: new perspectives in cardiovascular medicine. | Thrombin converts fibrinogen to fibrin and is the most powerful activator of platelets thus playing a crucial role in arterial and venous thrombosis. The limitations of heparin, largely used in the therapy of arterial and venous thromboembolism, has prompted the development of new antithrombotic drugs, able to directly... |
30,844 | Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank. | Venous thromboembolic events (VTE) are potentially preventable causes of morbidity and mortality after injury. We hypothesized that the current clinical incidence of VTE is relatively low and that VTE risk factors could be identified.</AbstractText>We queried the ACS National Trauma Data Bank for episodes of deep venou... |
30,845 | Improved imaging of deep venous thrombi during anticoagulation using radiolabelled anti-D-dimer antibodies. | Radiolabelled anti-fibrin antibodies have not yet enabled reliable and practical diagnosis of venous thromboembolism. However, previous unsuccessful clinical trials were performed with anti-fibrin beta-chain antibodies that do not optimally bind to thrombi during anticoagulation. The current experiments were performed ... |
30,846 | Thromboembolism following removal of femoral venous apheresis catheters in patients with breast cancer. | Apheresis catheters have simplified collection of peripheral blood stem cells (PBSC), but may be associated with thrombosis of the instrumented vessels. We performed a retrospective analysis to study the prevalence of thromboembolism associated with the use of femoral apheresis catheters in patients with breast cancer.... |
30,847 | Extended venous thrombosis in Adamantiades-Behçet's disease. | A 27-year-old male patient presented with new thrombotic areas and undiagnosed partially old thrombosis of both vena femoralis, vena iliaca externa, vena iliaca communis and the vena cava inferior. He reported episodes of orchitis, recurrent oral aphthous ulcers, mild arthritis of several joints, recurrent iridocycliti... |
30,848 | Placement of inferior vena cava filters in bariatric surgical patients--possible indications and technical considerations. | Surgical treatment of the morbidly obese has assumed an increasingly important role in both the academic and community setting, while postoperative pulmonary embolism remains a devastating complication. Since the overall incidence remains low, the role for vena cava filter placement in this group is not yet well define... |
30,849 | An approach to venous thromboembolism prophylaxis in laparoscopic Roux-en-Y gastric bypass surgery. | Venous thromboembolism (VTE) prophylaxis regimens for laparoscopic Roux-en-Y gastric bypass (LRYGBP) have not been adequately addressed in the literature. This study presents the results of our prophylactic regimen in LRYGBP at a tertiary care hospital.</AbstractText>A retrospective review of 255 morbidly obese patient... |
30,850 | Spontaneous bilateral internal jugular vein thrombosis: a sign of metastasis. | Head and neck swellings are common referrals to the otolaryngology department, with a wide range of aetiologies. Internal jugular vein thrombosis presenting as swelling in the neck is a rare occurrence. The authors report a case of bilateral internal jugular vein thrombosis secondary to malignant lymphadenopathy of unk... |
30,851 | [Current concepts of venous thromboembolism and anticoagulation during pregnancy]. | The pregnancy is a physiologic state with an elevated risk for thromboembolic complications. Clinical diagnosis and many diagnostic tests are less accurate in pregnant than in nonpregnant patients. The principal indications for anticoagulation during pregnancy include treatment and prophylaxis of deep vein thrombosis a... |
30,852 | Prevention of venous thromboembolism in the plastic surgery patient. | The term venous thromboembolism refers to a spectrum of disease that includes deep venous thrombosis and pulmonary embolism. Both deep venous thrombosis and pulmonary embolism are often clinically silent and thus difficult to diagnose, which leads to a substantial delay in treatment that results in high rates of morbid... |
30,853 | Pharmacoeconomics of thrombosis management. | Venous thromboembolism (VTE) is the cause of significant morbidity and mortality and may lead to other complications, including recurrent VTE and long-term postthrombotic syndrome. Venous thromboembolism represents a huge health economic burden of nearly 500 million dollars/year in the United States. Without adequate p... |
30,854 | Evolving concepts in the treatment of venous thromboembolism: the role of factor Xa inhibitors. | Anticoagulation is an essential component of the care of patients with venous thromboembolism (VTE). Traditional anticoagulants for the treatment of VTE include unfractionated heparin (UFH), low-molecular-weight heparin (LMWH), and the oral vitamin K antagonist, warfarin. A variety of anticoagulant agents with improved... |
30,855 | Evidence for extended prophylaxis in the setting of orthopedic surgery. | Patients undergoing orthopedic surgery represent one of the highest risk groups for the development of venous thromboembolism (VTE). Evidence shows that this risk extends beyond the period in which the patient is hospitalized, especially for patients undergoing hip surgery. Clinical trials have shown that extended prop... |
30,856 | Emerging options for thromboprophylaxis after orthopedic surgery: a review of clinical data. | In four randomized, controlled studies of patients undergoing orthopedic surgery, the antithrombotic efficacy and safety of subcutaneous fondaparinux 2.5 mg once/day were compared with those of subcutaneous enoxaparin regimens that were approved by the United States Food and Drug Administration. In patients undergoing ... |
30,857 | Long-term outcome of radiological-guided insertion of implanted central venous access port devices (CVAPD) for the delivery of chemotherapy in cancer patients: institutional experience and review of the literature. | Central venous access port devices (CVAPD) are necessary for delivery of prolonged infusional chemotherapy or in patients with poor peripheral venous access. Previous studies of Hickman catheters report complication rates in about 45% of patients. Our aim was to assess the early and late complication rate, and duration... |
30,858 | Low-molecular-weight heparin for the prevention and treatment of venous thromboembolism in pregnancy. | Low-molecular-weight heparins (LMWHs) have largely replaced unfractionated heparins for both prophylaxis and treatment of venous thromboembolism in nonpregnant patients. However, until recently, evidence in pregnant women was lacking, despite the increasing use of LMWHs during pregnancy in clinical practice. This revie... |
30,859 | Prophylaxis of venous thromboembolism in medical patients. | Venous thromboembolism is a multifactorial silent disease and tends not to be suspected by physicians, especially in medical patients. Pulmonary embolism is the most preventable cause of death among hospitalized patients. It is of major importance to assess the risk for venous thromboembolism and to adapt the prophylac... |
30,860 | Complete compression ultrasound for the diagnosis of venous thromboembolism. | Since its first appearance in the 1980s, venous ultrasound has increasingly gained interest of both clinicians and researchers. However, a majority of authors currently are convinced that venous ultrasound has inherent limitations that preclude it from safely ruling out distal deep vein thrombosis (DVT) in symptomatic ... |
30,861 | Pentasaccharides in the prophylaxis and treatment of venous thromboembolism: a systematic review. | The aim of this review is to perform a critical analysis of all completed studies evaluating pentasaccharides-synthetically derived, selective inhibitors of activated factor X-in prophylaxis in major orthopedic surgery and the treatment of venous thromboembolism.</AbstractText>Venous thromboembolism is a disorder with ... |
30,862 | Extensive forearm deep venous thrombosis following a severe infliximab infusion reaction. | Here we describe a patient with Crohn's disease who developed a severe infliximab infusion reaction (IIR), complicated 1 day later by severe swelling of the forearm and hand ipsilateral to the site of infliximab infusion. This proved to be extensive forearm deep venous thrombosis. The site of thrombosis and the chronol... |
30,863 | Cerebrovascular complications in patients with malignancy: report of three cases and review of the literature. | A cerebrovascular thromboembolic event may precede the identification of cancer, and be the first clinical evidence of an underlying malignancy. The malignancy can cause either nonbacterial thrombotic endocarditis or hypercoagulable state, both of which may have clinical manifestions such as thrombotic or embolic occlu... |
30,864 | [Antibiotic prophylaxis and therapy in dental surgery]. | Antibiotics are used for prophylactic and therapeutic indications. Since the conditions caused by bacteria resistance are in constant modification the regime has to be verified at regular intervals and adapted to the new conditions. The prescription of antibiotics in oral surgery and medicine should be administrated wi... |
30,865 | Paroxysmal nocturnal hemoglobinuria. | Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder resulting from a somatic mutation in the hematopoietic stem cell. It is characterized by intravascular hemolysis, cytopenias, frequent infections, bone marrow hypoplasia, and a high incidence of life-threatening venous thrombosis. An abs... |
30,866 | Perioperative anticoagulation: looking through heparin window.<Pagination><StartPage>21</StartPage><EndPage>34</EndPage><MedlinePgn>21-5; quiz 33-4</MedlinePgn></Pagination><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hartsell</LastName><ForeName>Zachary C</ForeName><Initials>ZC</Initials><AffiliationInfo><... | 24,564 autopsy protocols from the central city hospital and oncology dispensary were analyzed in order to evaluate the rate and dynamics of postoperative thrombotic complications (PTC). The PTC rate was 14.89% and went up two-fold within the recent 20 years. The rate of pulmonary thromboembolism (PTE) was 10.13%; it in... |
30,867 | A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding. | The provision of adequate iron to support erythropoiesis in iron deficient patients is a time-consuming process which may present compliance problems for patients in the outpatient setting. The aim of the present study was to evaluate the safety and tolerability of intravenous high-dose iron sucrose therapy specificall... |
30,868 | [Thrombin: antithrombotic properties and pharmacological consequences]. | During the last few years, the availability of endothelial cell cultures isolated from different vascular regions contributed to a significant increase in understanding the complex pro- and antithrombotic mechanisms in our circulatory system. The most important key enzyme is thrombin. Due to its haemostatic properties ... |
30,869 | [Home treatment for deep vein thrombosis: pros and cons]. | There is sound evidence, that low molecular weight heparin (LMWH) administered subcutaneously is at least as effective and safe as an i.v. infusion of unfractionated heparin. Thus, with LMWH out-patient treatment of deep vein thrombosis (DVT) becomes feasible. According to the current guidelines, an objective diagnosis... |
30,870 | Treatment of refractory status epilepticus with inhalational anesthetic agents isoflurane and desflurane. | Refractory status epilepticus (RSE) is defined as continued seizures after 2 or 3 antiepileptic drugs have failed. Several intravenous agents have been used for RSE; however, problems occur with their toxicity and/or effectiveness.</AbstractText>To report our experience with inhalational anesthesia (IA) in patients who... |
30,871 | Below-knee elastic compression stockings to prevent the post-thrombotic syndrome: a randomized, controlled trial. | Because only limited evidence suggests that elastic stockings prevent the post-thrombotic syndrome in patients with symptomatic deep venous thrombosis (DVT), these stockings are not widely used.</AbstractText>To evaluate the efficacy of compression elastic stockings for prevention of the post-thrombotic syndrome in pat... |
30,872 | Modified Sugiura procedure for the management of 160 cirrhotic patients with portal hypertension. | Portal hypertension is a common disease with a high mortality and serious effect on the life quality of patients. Presently, shunt and disconnection are commonly used for surgical treatment of portal hypertension. The aim of this study was conducted to analyze the results of a modified Sugiura procedure for the managem... |
30,873 | Surgical treatment of 1360 cases of Budd-Chiari syndrome: 20-year experience. | Budd-Chiari syndrome (BCS) is a disease caused by blood flow obstruction of the main hepatic veins (MHVs) and/or the outlet of the inferior vena cava (IVC), characterized by retrohepatic portal hypertension (PHT) and/or IVC hypertension. In the past decade, over 3000 cases of BCS have been reported in China. This study... |
30,874 | Orthotopic liver transplantation for patients with hepatocellular carcinoma complicated by portal vein tumor thrombi. | Orthotopic liver transplantation (OLT) has been the valuable treatment of choice for patients with hepatocellular carcinoma (HCC). As the number of patients with portal vein tumor thrombi (PVTT) increases, most transplant centers become suspicious of the exact effect of the operation which has been accepted as a radica... |
30,875 | The influence of hemodynamics and wall biomechanics on the thrombogenicity of vein segments perfused in vitro. | This study addresses the hypothesis that exposure to peripheral arterial (ART) or coronary (COR) hemodynamics and wall biomechanics affect platelet deposition on vein segments. Intact human saphenous vein (HSV) and porcine internal jugular vein (PIJV) segments were studied under venous (VEN), ART, and COR environments ... |
30,876 | Statins but not fibrates are associated with a reduced risk of venous thromboembolism: a hospital-based case-control study. | Previous studies of selected patients have suggested a reduction in the risk of venous thromboembolism with the use of statins. The objective of this study is to evaluate the influence of statin use on the risk of venous thromboembolic (VTE) events. The study is a case-control study (EDITH: Etude des Déterminants ... |
30,877 | A transcranial approach for direct mechanical thrombectomy of dural sinus thrombosis. Report of two cases. | Cerebral venous sinus thrombosis is often difficult to manage. Treatment options include systemically delivered anticoagulation therapy or chemical thrombolysis. Targeted endovascular delivery of thrombolytic agents is currently a popular option, but it carries an increased risk of hemorrhage. These strategies require ... |
30,878 | Successful treatment with stent angioplasty for Budd-Chiari syndrome in Behçet's disease. | Budd-Chiari syndrome (BCS) is a very rare vascular complication of Behçet's disease (BD) which often leads to death as a result of portal hypertension and liver failure. We report a 45-year-old BD patient who presented with BCS. Diagnosis was confirmed with CT scan and contrast-enhanced MR angiography which showed... |
30,879 | Safety profile of raloxifene as used in general practice in England: results of a prescription-event monitoring study. | Raloxifene, a selective estrogen receptor modulator (SERM) licensed for the prevention of non-traumatic vertebral fractures in postmenopausal women at increased risk of osteoporosis, was launched in the UK in August 1998. The aim of the study was to monitor the safety of raloxifene prescribed in the primary care settin... |
30,880 | Lipoprotein(a) and the link between atherosclerosis and thrombosis. | Elevated plasma concentrations of lipoprotein(a) (Lp[a]) have been consistently shown to be a risk factor for the development of a variety of thrombotic and atherosclerotic disorders including coronary artery disease. However, the mechanisms by which Lp(a) mediates its apparent pathophysiological effects remain to be c... |
30,881 | [Optic neurotomy for central retinal vein occlusion]. | To investigate the surgical effect and complication of optic neurotomy for ischemic central retinal vein occlusion (CRVO).</AbstractText>Eight patients elected to undergo optic neurotomy, The age range was 32 - 67 years, Five of the 8 were women and three were men. The duration of the CRVO were 3 - 8 months. Systemic h... |
30,882 | The prevention and treatment of deep vein thrombosis. | Deep vein thrombosis can have serious long-term consequences and can result in fatal complications. Many patients are at increased risk of DVT, but knowledge of common risk factors and an awareness of appropriate prophylactic measures can help prevent its occurrence. An ability to recognise common clinical signs and sy... |
30,883 | Chron's disease, rare association with selective IgA immunodeficiency, and development of life-threatening bacterial infections. | Life-threatening necrotizing fasciitis and relapsing Lemierre syndrome associated with Fusobacterium necrophorum septicaemia occurred in young adults with a moderate Chron's disease and a missed profound IgA deficiency. This unexpected association of a chronic bowel inflammatory syndrome with prominent IgA abnormalitie... |
30,884 | [D-dimer in the early detection of deep vein thrombosis in the lower extremity]. | Deep vein thrombosis is important social and health care problem for its high incidence, pulmonary embolism-related mortality, and long-term sequelae which may be disabling (post-thrombotic syndrome and ulceration). The aim of our work was to determine the diagnostic potential and importance of D dimer in the early det... |
30,885 | [Unilateral decompressive craniectomy in left transverse and sigmoid sinus thrombosis]. | Cerebral venous and dural sinus thrombosis is a rare cause of stroke. We explore the controversial issue of anticoagulation therapy and indication for decompressive craniectomy in association with severe sinus thrombosis. The 62-year-old female patient was admitted to hospital, because of first generalized seizure. A c... |
30,886 | Successful limb reperfusion using prolonged intravascular shunting in a case of an unstable trauma patient--a case report. | When peripheral vascular injuries present in conjunction with life threatening emergencies, controlling hemorrhage from a peripheral blood vessel may take initial priority, however, sacrificing a limb to preserve life is a well-established dictum. The use of intravascular shunts has allowed arterial and venous injuries... |
30,887 | Fate of great saphenous vein after radio-frequency ablation: detailed ultrasound imaging. | Radio-frequency ablation (RFA) of the great saphenous vein (GSV) is an endovascular alternative to stripping. To determine long-term effectiveness, the fate of GSV treated for valvular insufficiency with RFA was evaluated in detail with ultrasound imaging (US). One hundred lower extremities were examined with high-reso... |
30,888 | Long term use of oral contraceptives without thrombosis in patients with FV Leiden polymorphism: a study of 37 patients (2 homozygous and 35 heterozygous). | It is commonly accepted that women on oral contraceptive therapy have about a four fold increased incidence of venous thrombosis in comparison to non users. Women with FV Leiden polymorphism have an even higher incidence. The purpose of the paper is to show that women with FV Leiden polymorphism may sometimes remain as... |
30,889 | The occasional venous thromboses seen in patients with severe (homozygous) FXII deficiency are probably due to associated risk factors: a study of prevalence in 21 patients and review of the literature. | According to our personal experience and to the study of the literature, 11 cases of venous thrombosis have been described as sporadic reports in patients with severe (homozygous) factor XII (FXII) deficiencies. In every cases but 4, associated risk factors were found to be present (pregnancy, post-partum period, surge... |
30,890 | Plasma levels of factor XII, prekallikrein and high molecular weight kininogen in normal blood donors and patients having suffered venous thrombosis. | The contact system proteins factor XII (FXII), prekallikrein (PK) and high molecular weight kininogen (HK) have roles in coagulation, fibrinolysis, thrombin-induced platelet activation, cell adhesion and angeogenisis. It has been suggested that inherited or acquired deficiencies of these proteins may be risk factors fo... |
30,891 | Comparison between CoaguChek S- and Owren-type prothrombin time assay for monitoring anticoagulant therapy. | Anticoagulation therapy with warfarin is monitored by the prothrombin time (PT) assay. The PT is standardized using international normalized ratios (INRs). By keeping the INR within specific values, it is possible to reduce potential complications from the treatment. To facilitate the PT monitoring, point-of-care devic... |
30,892 | Differences in platelet activation by prolactin and leptin. | Hormones such as prolactin and leptin have recently been recognized as potent platelet aggregation co-activators, and have therefore been postulated as an additional risk factor for both arterial and venous thrombosis. Clinical situations exist that are known to be associated with higher leptin and/or prolactin levels ... |
30,893 | Anomalies of the fetal venous system: a report of 26 cases and review of the literature. | To evaluate sonographic appearance, natural history, and neonatal outcome of fetal venous anomalies.</AbstractText>We performed an observational study, including all fetuses affected by abnormalities of the venous system diagnosed by ultrasound during the prenatal period.</AbstractText>26 fetuses were identified. Other... |
30,894 | Deep vein thrombosis: prevalence and risk factors in rehabilitation admissions with brain injury. | To determine the prevalence and risk factors of deep vein thrombosis (DVT) among neurorehabilitation admissions with acquired brain injury (BI).</AbstractText>In this prospective, sequential case series, 709 consecutive initial neurorehabilitation patients with BI < 120 days-including traumatic brain injury (TBI; n ... |
30,895 | Characterization and comparative evaluation of a structurally unique PAI-1 inhibitor exhibiting oral in-vivo efficacy. | Plasminogen activator inhibitor-1 (PAI-1) is the major physiological inhibitor of both tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). Elevated levels of PAI-1 are associated with thrombosis and vascular disease, suggesting that high plasma PAI-1 may promote a hypercoagulable sta... |
30,896 | Effect of age on the incidence of venous thromboembolism after major surgery. | Most guidelines for administration of thromboprophylaxis after major surgery use age as a major predictor of postoperative venous thromboembolism (VTE). We sought to quantify the effect of age on the risk of symptomatic VTE after a spectrum of surgical procedures.</AbstractText>Using the California Patient Discharge Da... |
30,897 | Beta-receptor blockade decreases elevated plasma levels of factor VIII:C in patients with deep vein thrombosis. | An elevated plasma level of factor VIII:C (FVIII:C) is a strong and dose-dependent risk factor for venous thromboembolism (VTE). The cause of elevated FVIII:C in patients with thrombophilia is as yet unknown. FVIII:C increases significantly after infusion of epinephrine, vasopressin or physical exercise. The aim of the... |
30,898 | Fixed-dose low-molecular-weight heparin for secondary prevention of venous thromboembolism in patients with disseminated cancer: a prospective cohort study. | Secondary prevention of venous thromboembolism (VTE) with vitamin K antagonists is often problematic in patients with cancer. We prospectively evaluated the effectiveness and safety of long-term subcutaneous dalteparin in a series of consecutive patients with symptomatic VTE and metastatic cancer.</AbstractText>The stu... |
30,899 | Haplotypes of the EPCR gene, plasma sEPCR levels and the risk of deep venous thrombosis. | Binding of protein C (PC) to the endothelial cell PC receptor (EPCR) stimulates PC activation by increasing the affinity of PC for the thrombin-thrombomodulin complex. A soluble form of this receptor (sEPCR) circulates in plasma and inhibits both PC activation and APC anticoagulant activity.</AbstractText>The aim of th... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.