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5,200 | The autonomic nervous system in cardiac electrophysiology: an elegant interaction and emerging concepts. | The autonomic nervous system plays an integral role in the modulation of normal cardiac electrophysiology. This is achieved via a complex network of pre- and postganglionic sympathetic and parasympathetic fibers that synapse on extrinsic and intrinsic cardiac ganglia and ultimately directly innervate cardiac myocytes. ... |
5,201 | The impact of rapid atrial pacing on ADMA and endothelial NOS. | The endothelial nitric oxide synthase (eNOS) inhibitor asymmetric dimethylarginine (ADMA) is a well-established risk factor for oxidative stress, vascular dysfunction, and congestive heart failure. The aim of the present study was to determine the impact of rapid atrial pacing (RAP) on ADMA levels and eNOS expression.<... |
5,202 | Domperidone and ventricular arrhythmia or sudden cardiac death: a population-based case-control study in the Netherlands. | Recently, a 4-fold increase in risk of sudden cardiac death (SCD) was reported for domperidone in a study that focused on corrected QT interval (QTc)-prolonging drugs as a class and their association with SCD.</AbstractText>To evaluate the association between the use of domperidone and serious non-fatal ventricular arr... |
5,203 | Differential action of two prolactin isoforms on ischemia and re-perfusion-induced arrhythmias in rats in vivo. | The different influences of one of the PRL isoforms (PRL I) on the cardiovascular system have been described in the past.</AbstractText>Our goal was to establish an appropriate iv dose of 2 PRL isoforms (PRL I and PRL II) in intact rats. After establishing this dose, PRL I (0.01 mg/kg) or PRL II (0.001 mg/kg) was admin... |
5,204 | Green tea extract given before regional myocardial ischemia-reperfusion in rats improves myocardial contractility by attenuating calcium overload. | There is evidence for a negative correlation between green tea consumption and cardiovascular diseases. The aim of the present study was to examine whether green tea extract (GTE) given before regional myocardial ischemia could improve depression of myocardial contractility by preventing cytosolic Ca(2+) overload. Regi... |
5,205 | Three-dimensional echocardiography using single-heartbeat modality decreases variability in measuring left ventricular volumes and function in comparison to four-beat technique in atrial fibrillation. | Three dimensional echocardiography (3DE) approaches the accuracy of cardiac magnetic resonance in measuring left ventricular (LV) volumes and ejection fraction (EF). The multibeat modality in comparison to single-beat (SB) requires breath-hold technique and regular heart rhythm which could limit the use of this techniq... |
5,206 | [Four-week Levitronix Centrimag bridge-to-transplant for post myocardial infarction cardiogenic shock. A case report]. | Cardiogenic shock after myocardial infarction has a high mortality even if early revascularization is achieved. Biventricular assist devices have not been used in Chile in this critical setting. We report a case of a 55-year-old diabetic man who suffered an acute chest pain and ventricular fibrillation. Prompt outside ... |
5,207 | Incidence and predictors of subclavian vein obstruction following biventricular device implantation. | The data about the incidence of subclavian venous (SCV) obstruction or thrombosis after biventricular device implantation is limited. Therefore, we aimed to assess the incidence and predictors of venous obstruction after biventricular device implantation with or without a defibrillator in patients with left ventricular... |
5,208 | Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation. | To investigate whether hypothermia could be induced pharmacologically after resuscitation with the cannabinoid CB1/CB2 receptor agonist in a rat model and its effects on outcomes of cardiopulmonary resuscitation.</AbstractText>Prospective, randomized, placebo-controlled experimental study.</AbstractText>University-affi... |
5,209 | Predictors of resuscitation in a swine model of ischemic and nonischemic ventricular fibrillation cardiac arrest: superiority of amplitude spectral area and slope to predict a return of spontaneous circulation when resuscitation efforts are prolonged. | We have demonstrated that a return of spontaneous circulation in the first 3 mins of resuscitation in swine is predicted by ventricular fibrillation waveform (amplitude spectral area or slope) when untreated ventricular fibrillation duration or presence of acute myocardial infarction is unknown. We hypothesized that in... |
5,210 | A patient with commotio cordis successfully resuscitated by bystander cardiopulmonary resuscitation and automated external defibrillator. | Sudden deaths of children and adolescents during competitive sports are usually due to congenital heart diseases. Ventricular fibrillation, however, may also occur in individuals with no underlying cardiac disease who have sustained a low-impact chest wall blow. This phenomenon is described as commotio cordis, and the ... |
5,211 | Moderate exercise prevents impaired Ca2+ handling in heart of CO-exposed rat: implication for sensitivity to ischemia-reperfusion. | Sustained urban carbon monoxide (CO) exposure exacerbates heart vulnerability to ischemia-reperfusion via deleterious effects on the antioxidant status and Ca(2+) homeostasis of cardiomyocytes. The aim of this work was to evaluate whether moderate exercise training prevents these effects. Wistar rats were randomly assi... |
5,212 | Left atrial volume index as a predictor for occurrence of atrial fibrillation after ablation of typical atrial flutter. | Radiofrequency catheter ablation of the cavotricuspid isthmus (CTI) is effective in the treatment of typical atrial flutter (AFL) and atrial fibrillation (AF). AF and AFL often coexist. However, AF often occurs following successful ablation of CTI. The aim of this study was to investigate the predictors of concomitant ... |
5,213 | Clinical, electrocardiographic, and electrophysiologic characteristics of patients with a fasciculoventricular pathway: the role of PRKAG2 mutation. | The ECG, clinical, and electrophysiologic profiles of patients with a fasciculoventricular pathway are well described. Fasciculoventricular pathways occurring in the setting of glycogen storage cardiomyopathy possess unique features.</AbstractText>The purpose of this study was to compare the clinical, ECG, and electrop... |
5,214 | An ECG index of myocardial scar enhances prediction of defibrillator shocks: an analysis of the Sudden Cardiac Death in Heart Failure Trial. | Only a minority of patients receiving implantable cardioverter-defibrillators (ICDs) for the primary prevention of sudden death receive appropriate shocks, yet almost as many are subjected to inappropriate shocks and device complications. Identifying and quantifying myocardial scar, which forms the substrate for ventri... |
5,215 | Left-ventricular electromechanical delay is prolonged in patients with postoperative atrial fibrillation. | Although several risk factors for postoperative atrial fibrillation (AF) have been proposed, it remains the most common complication after cardiac surgery, even in low-risk patients. There is still no single reliable and reproducible parameter for predicting AF, and no standardized recommendation exists for this issue.... |
5,216 | Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation. | The aim of this study was to evaluate the effectiveness of a combination of dronedarone and ranolazine in suppression of atrial fibrillation (AF).</AbstractText>Safe and effective pharmacological management of AF remains one of the greatest unmet medical needs.</AbstractText>The electrophysiological effects of dronedar... |
5,217 | Clinical and mechanistic issues in early repolarization of normal variants and lethal arrhythmia syndromes. | Early repolarization, involving ST-segment elevation and, sometimes, prominent J waves at the QRS-ST junction, has been considered a normal electrocardiographic variant for over 60 years. A growing number of case reports and case-control studies indicate that in some instances, early repolarization patterns are associa... |
5,218 | Ranolazine safely decreases ventricular and atrial fibrillation in Timothy syndrome (LQT8). | Long QT eight (LQT8), otherwise known as Timothy syndrome (TS), is a genetic disorder causing hyper-activation of the L-type calcium channel Cav 1.2. This calcium load and the resultant increase in the QT interval provide the substrate for ventricular arrhythmias. We previously presented a case in a patient with TS who... |
5,219 | A novel echocardiographic marker in hypertensive patients: is diastolic dysfunction associated with atrial electromechanical abnormalities in hypertension? | Atrial arrhythmias are common problems in hypertensive patients. Atrial electromechanical delay (AEMD) can be used to evaluate development of atrial arrhythmias. The authors aimed to assess inter- and intra-AEMD in hypertensive patients. The study population consisted of 200 medically treated hypertensive patients and ... |
5,220 | Pulmonary Vein Sleeves as a Pharmacologic Model for the Study of Atrial Fibrillation. | To review the electrophysiologic effects of antiarrhythmic agents in pulmonary veins (PV) sleeve preparations.</AbstractText>Ectopic activity arising from the PV plays a prominent role in the development of atrial fibrillation.</AbstractText>Transmembrane action potentials were recorded from canine superfused left supe... |
5,221 | MRI-Guided Electrophysiology Intervention. | Catheter ablation is a first-line treatment for many cardiac arrhythmias and is generally performed under X-ray fluoroscopy guidance. However, current techniques for ablating complex arrhythmias such as atrial fibrillation and ventricular tachycardia are associated with sub-optimal success rates and prolonged radiation... |
5,222 | Cardiac arrhythmias and left ventricular hypertrophy in systemic hypertension. | Hypertensive left ventricular hypertrophy (LVH) is associated with increased risk of arrhythmias and mortality. Objective was to investigate the prevalence of cardiac arrhythmias and LVH in systemic hypertension.</AbstractText>In all subjects blood pressure was measured, electrocardiography and echocardiography was don... |
5,223 | Incidence of, predictors for, and mortality associated with malignant ventricular arrhythmias in non-ST elevation myocardial infarction patients. | The incidence of non-ST elevation myocardial infarction (NSTEMI) is increasing. Although life-threatening ventricular arrhythmias have been well-documented in patients with ST elevation MI (STEMI), their incidence and importance in NSTEMI have not been examined in similar detail. We examined the incidence, predictors, ... |
5,224 | Brugada syndrome with aborted sudden cardiac death related to liquorice-induced hypokalemia. | It was the aim of this study to report an aborted cardiac arrest due to ventricular fibrillation and electrocardiographic changes consistent with Brugada syndrome due to liquorice-induced hypokalemia.</AbstractText>Ventricular fibrillation was witnessed in a 50-year-old woman who was admitted to our emergency departmen... |
5,225 | Homocysteine levels in patients with heart failure with preserved ejection fraction. | Increased homocysteine (HCY) levels are associated with an increased risk of cardiovascular disease. Plasma HCY is increased in chronic heart failure (CHF) patients, and previous studies suggest that hyperhomocysteinemia causes adverse cardiac remodeling and affects pump function. We aimed to evaluate the HCY levels in... |
5,226 | Decreased apoptosis following successful ablation of atrial fibrillation. | Increased apoptotic processes in tissue samples from hearts in atrial fibrillation (AF) have been previously documented in animals. Whether the restoration of sinus rhythm is associated with decreased apoptosis is not known. The aim of the present study was to establish whether successful epicardial ablation of AF lead... |
5,227 | Heart rate-dependent variability of cardiac events in type 2 congenital long-QT syndrome. | We aimed to examine the validity of heart rate (HR) at rest before β-blocker therapy as a risk factor influencing cardiac events (ventricular fibrillation, torsades de pointes, or syncope) in long QT type 2 (LQT2) patients.</AbstractText>In 110 genetically confirmed LQT2 patients (45 probands), we examined the si... |
5,228 | Characteristics and clinical outcome of 458 patients with acute myocardial infarction requiring mechanical ventilation. Results of the BEAT registry of the ALKK-study group. | Information about the clinical course of patients with acute myocardial infarction requiring mechanical ventilation is scarce. We sought to evaluate the clinical outcome of a large cohort of such patients in clinical practice.</AbstractText>The German BEAT registry prospectively enrolled consecutive patients requiring ... |
5,229 | Report from J-PULSE multicenter registry of patients with shock-resistant out-of-hospital cardiac arrest treated with nifekalant hydrochloride. | Nifekalant hydrochloride (NIF) is an intravenous class-III antiarrhythmic agent that purely blocks the K(+)-channel without inhibiting β-adrenergic receptors. The present study was designed to investigate the feasibility of NIF as a life-saving therapy for out-of-hospital ventricular fibrillation (VF).</AbstractT... |
5,230 | Numerically simulated cardiac exposure to electric current densities induced by TASER X-26 pulses in adult men. | There is still an ongoing debate whether or not electronic stun devices (ESDs) induce cardiac fibrillation. To assess the ventricular fibrillation risk of law enforcing electronic control devices, quantitative estimates of cardiac electric current densities induced by delivered electric pulses are essential. Numerical ... |
5,231 | Downloadable software algorithm reduces inappropriate shocks caused by implantable cardioverter-defibrillator lead fractures: a prospective study. | Downloadable software upgrades are common in consumer electronics but not in implantable medical devices. Fractures of implantable cardioverter-defibrillator (ICD) leads present commonly as inappropriate shocks. A lead-integrity alert (LIA) designed to reduce inappropriate shocks is the first software download approved... |
5,232 | Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643. | Human ether-à-go-go-related gene 1 (hERG1) channels conduct the rapid delayed rectifier K+ current, I(Kr), an important determinant of action potential repolarization in mammals, including humans. Reduced I(Kr) function caused by mutations in KCNH2 or drug block of hERG1 channels prolongs the QT interval of the el... |
5,233 | Cavotricuspid isthmus dependent flutter is associated with an increased incidence of occult coronary artery disease. | Atrial flutter (AFl) and atrial fibrillation (AFib) share many clinical risk factors and potential mechanisms with atherosclerosis. Despite this, an association between stable coronary artery disease (CAD) and atrial arrhythmias has not previously been documented. To investigate this hypothesis we measured the incidenc... |
5,234 | Endocardial vagal atrioventricular node stimulation in humans: reproducibility on 18-month follow-up. | Control of atrioventricular (AV) node conduction by means of high-frequency stimulation (HFS) of efferent AV node vagal stimulation (AVNS) fibres enables the ventricular rate (VR) to be modulated during atrial fibrillation (AF). The aims of this study were to verify, on 18-month follow-up, the reproducibility of the dr... |
5,235 | Therapeutic medical hypothermia--a multispecialty approach. | Cardiac arrest remains one of the most common causes of death in developed countries. Those who survive may have significant neurologic morbidity. In the current decade, therapeutic medical hypothermia (TMH) has emerged as the only treatment that unequivocally improves neurologic outcomes in post ventricular fibrillati... |
5,236 | Effects of tirofiban and percutaneous coronary intervention in an old patient with acute myocardial infarction and cardiogenic shock. | A 75 year old man presented in our institutition with acute inferoposterior and right ventricular ST-segment elevation myocardial infarction and cardiogenic shock, 40 minutes after the pain onset. He was pretreated with 300 mg of aspirin, 600 mg of clopidogrel, and was taken to the catheterization laboratory. Door to n... |
5,237 | Clinical observation on the treatment of atrial fibrillation with amiodarone combined with Shenmai Injection (参麦注射液). | To observe the therapeutic efficacy and safety of amiodarone combined with Shenmai Injection (参麦注射液) on atrial fibrillation.</AbstractText>A total of 351 patients with atrial fibrillation caused by cardiovascular diseases and idiopathic atrial fibrillation were assigned to amiodarone ... |
5,238 | Evaluation of cardiac arrhythmia among athletes. | Due to the growing awareness of exercise-related arrhythmias and improved sensitivity of diagnostic modalities, physicians are increasingly faced with choices that may have life-changing impact for the athlete. This article surveys recent research and expert opinion addressing benign and pathogenic cardiac changes unde... |
5,239 | Assessment of left atrial appendage function during sinus rhythm in patients with hypertrophic cardiomyopathy: transesophageal echocardiography and tissue doppler study. | The incidence of systemic thromboembolism is high in patients with hypertrophic cardiomyopathy (HCM). The authors hypothesized that vulnerability to such vascular events could be caused by depressed left atrial appendage (LAA) function during normal sinus rhythm (SR). The aim of this cross-sectional study was to invest... |
5,240 | Risk of cardiac arrhythmias and conduction abnormalities in patients with acute myocardial infarction receiving packed red blood cell transfusions. | Although transfusion has been linked to the development of atrial fibrillation (AF) in cardiac surgical patients, this association has not been investigated in patients with acute myocardial infarction (AMI). Evidence supports an inflammatory mechanism in the development of AF, and red cell transfusions also elicit an ... |
5,241 | Fetal right ventricular myocardial function is better preserved by fibrillatory arrest during fetal cardiac bypass. | Protection and preservation of fetal myocardial function are important for successful fetal intracardiac repair. Our objective was to determine fetal biventricular cardiac performance after two cardiac-arrest techniques.</AbstractText>Three groups of midterm ovine fetuses underwent 90-minute bypass. A control group (no... |
5,242 | Early afterdepolarizations and cardiac arrhythmias. | Early afterdepolarizations (EADs) are an important cause of lethal ventricular arrhythmias in long QT syndromes and heart failure, but the mechanisms by which EADs at the cellular scale cause arrhythmias such as polymorphic ventricular tachycardia (PVT) and torsades de pointes (TdP) at the tissue scale are not well und... |
5,243 | Recurrent ventricular arrhythmias and myocardial infarctions associated with cocaine induced reversible coronary vasospasm. | Cocaine has become the most frequently used illicit drug among patients presenting to emergency departments worldwide. Although acute myocardial infarction is the most common reported cardiovascular manifestation in this setting, there are many other potential cardiotoxic effects of cocaine use including coronary arter... |
5,244 | Does atrial fibrillation affect plasma endothelin level? | Atrial fibrillation (AF) may result in endocardial endothelium dysfunction. The main objective of the study was to evaluate the plasma concentration of endothelin-1 (ET-1) during persistent AF and after sinus rhythm recovery following direct-current cardioversion and to assess the predictive value of ET-1 in AF patient... |
5,245 | Active tissue factor and activated factor XI in circulating blood of patients with systolic heart failure due to ischemic cardiomyopathy. | Elevated clotting factors and thrombin generation have been reported to occur in patients with heart failure (HF). Circulating activated factor XI (FXIa) and active tissue factor (TF) can be detected in acute coronary syndromes and stable angina.</AbstractText>We investigated circulating FXIa and active TF and their as... |
5,246 | Intramural dyssynchrony and response to cardiac resynchronization therapy in patients with and without previous right ventricular pacing. | Right ventricular (RV) pacing is an iatrogenic cause of heart failure (HF) that has not been well studied. We assessed whether HF patients paced from the right ventricle (RVp) adversely remodel and respond to cardiac resynchronization therapy (CRT) in a similar way to HF patients without right ventricular pacing (nRVp)... |
5,247 | [Clinical applications of strain rate imaging for evaluation of left atrial function]. | Left atrial (LA) function plays an important role in patients with left ventricular dysfunction and atrial fibrillation, and has been assessed using several noninvasive methods. However, there are a number of limitations regarding clinical application, including the dependence of altered left ventricular hemodynamics, ... |
5,248 | Over 10 years with an implantable cardioverter-defibrillator - a long term follow-up of 60 patients. | Transvenous implantable cardioverter-defibrillators (ICD) have been implanted in Poland since 1995. As the method spreads it is important to consider its long-term benefits and disadvantages.</AbstractText>To assess survival, efficacy and complication rate in ICD patients, who received the device more than ten years ea... |
5,249 | New-onset versus chronic atrial fibrillation in acute myocardial infarction: differences in short- and long-term follow-up. | Atrial fibrillation (AF) occurs commonly in patients with acute myocardial infarction (AMI) and has been established as a marker of adverse prognosis. There are only few clinical trials that investigate differences between new-onset and chronic AF in AMI. We hypothesize that chronic AF is associated with an increased r... |
5,250 | Alcohol ablation at the posterior papillary muscle prevents ventricular fibrillation in swine without affecting mitral valve function. | Radiofrequency ablation at the posterior papillary muscle (PM) significantly reduced ventricular fibrillation (VF) inducibility in rabbits and dogs, suggesting that PM may be involved in the generation of VF. However, the effect of ablation at the PM on VF inducibility remains unknown in normal intact swine hearts beca... |
5,251 | [Coronary artery dissection in young adults]. | Two young patients, a 23-year-old man and a 30-year-old woman, without any risk factors for coronary artery disease, apart from the woman being a smoker, were admitted to our hospital because of acute myocardial infarction (MI) due to spontaneous dissection of a coronary artery (SDCA). The first patient developed acute... |
5,252 | Assessing the impact of prehospital intubation on survival in out-of-hospital cardiac arrest. | There is a developing body of literature documenting adverse survival outcome of out-of-hospital endotracheal intubation for critical multiple trauma and head injury patients.</AbstractText>To compare the rates of survival to hospital admission and discharge of nontraumatic out-of-hospital cardiac arrest (OHCA) patient... |
5,253 | Ventricular fibrillation associated with early repolarization in a patient with thyroid storm. | We present a case of a 69-year-old male who was hospitalized for the treatment of thyroid storm due to Grave's disease, who presented with unexpected ventricular fibrillation (VF). The possible etiology was early repolarization (ER), characterized by J-point elevation in inferior and posterolateral leads, unmasked by t... |
5,254 | B-type natriuretic peptide is predictive of postoperative events in orthopedic surgery. | [Corrected] Clinical assessment is not always sufficient to predict postoperative (PO) cardiac complications. B-type natriuretic peptide (BNP) has an important prognostic value in patients with heart failure. Its value as a predictor of events in orthopedic surgeries has not yet been tested.</AbstractText>To assess the... |
5,255 | Optimizing ICD programming for shock reduction. | With the increasing numbers of patients with implantable cardioverter/defibrillators for primary prevention (PP), the topic of inappropriate therapy becomes more and more important. If a shock intervention, e.g. for rapidly conducted atrial fibrillation or fast VT (FVT), represents the first reminder of the implantable... |
5,256 | Chronotropic incompetence and its relation to exercise intolerance in hypertrophic cardiomyopathy. | Diminished functional capacity is common in hypertrophic cardiomyopathy (HCM), although the underlying mechanisms are complicated. We studied the prevalence of chronotropic incompetence and its relation to exercise intolerance in patients with HCM.</AbstractText>Cardiopulmonary exercise testing was performed in 68 pati... |
5,257 | Left ventricular diastolic function and right atrial size are important rhythm outcome predictors after intraoperative ablation for atrial fibrillation. | Left ventricular (LV) diastolic function and right atrial (RA) size are not routinely included in preoperative echocardiographic examination in patients undergoing cardiac surgery with concomitant ablation for atrial fibrillation (AF).</AbstractText>To investigate the role of echocardiographic variables including LV di... |
5,258 | Ischemia-induced prominent J waves in a patient with Brugada syndrome. | A 75-year-old man was admitted to our hospital in January 2010 for evaluation of syncope and abnormal ECG. ECG showed type 1 ST elevation in lead V(1) and he was diagnosed as Brugada syndrome. During cardiac catheterization, baseline coronary angiography was normal, but intracoronary ergonovine maleate induced spasms o... |
5,259 | Increase in internal defibrillation threshold during acute myocardial infarction. | A 67-year-old man suffered an acute anteroseptal myocardial infarction complicated by multiple episodes of ventricular fibrillation, which were not systematically defibrillated by maximum, internal 35-J shocks delivered by an implanted cardioverter defibrillator (ICD). He had suffered from acute inferior myocardial inf... |
5,260 | Early and late cardiac ventricular reverse remodeling after catheter ablation for lone paroxysmal atrial fibrillation. | We sought to explore ventricular function in patients with lone paroxysmal atrial fibrillation (AF) and determine the mid- and long-term impact of pulmonary vein isolation on cardiac remodeling.</AbstractText>The relationship between tachyarrhythmia and ventricular dysfunction is still a matter of debate. Tachycardia-i... |
5,261 | Tricuspid regurgitation in patients with severe mitral regurgitation and normal left ventricular ejection fraction: risk factors and prognostic implications in a cohort of 895 patients. | Although tricuspid regurgitation (TR) is common in patients with mitral regurgitation (MR), its frequency, determinants and prognostic implications in those with severe MR and a normal left ventricular ejection fraction (LVEF) are not fully known. The study aim was to evaluate the risk factors for, and prognostic impli... |
5,262 | [Characteristics and the prognosis of patients with acute heart failure in current clinical practice]. | Analysis of predefined characteristics and outcomes in a non-selected population of patients hospitalized for acute heart failure (AHF) in Slovakia.</AbstractText>We conducted a nationwide prospective multicenter survey with 860 consecutive patients enrolled in 11 hospitals throughout Slovakia--two centres with a non-s... |
5,263 | [Changes in NT-proBNP levels in patients with atrial fibrillation related to heart failure]. | NT-proBNP, a well-established diagnostic and prognostic marker in clinical practice, is significantly elevated in individuals with atrial fibrillation (AF), even in absence of heart failure or major structural heart disease.</AbstractText>The aim of this study was to determine the cut-off value of NT-proBNP for diagnos... |
5,264 | Syncope, widened QRS interval, and left ventricular systolic depression: coincident with propafenone therapy for atrial fibrillation. | We report the case of a 46-year-old man who developed syncope, a widened QRS interval, and depressed left ventricular systolic function during propafenone therapy for atrial fibrillation. These acute findings may have been consequent to an increased dosage of propafenone combined with heavy alcohol consumption that led... |
5,265 | [Return of sinus rhythm in permanent atrial fibrillation patients at the time of the testing defibrillation during cardioverter-defibrillator implantation]. | Among patients, who underwent implantable cardioverter-defibrillator (ICD) implantation procedure, there are some, who have permanent atrial fibrillation (AF). There is a theoretical possibility of return of sinus rhythm at these patients during ventricular defibrillation testing at the time of the ICD implantation pro... |
5,266 | Superior vena cava syndrome: A rare complication of percutaneous nephrolithotripsy laser lithotripsy. | To describe a case of acute superior vena cava syndrome during percutaneous nephrolithotomy (PCNL), and to review the associated clinical features, management and complications.</AbstractText>A 34-year-old man, diagnosed as right renal calculi and nodal tachycardia, was admitted to receive percutaneous nephroscope lase... |
5,267 | Evaluation of noncontact mapping by comparison with simultaneous multisite contact recordings in acute ischemic ventricular fibrillation. | The study aim was to determine the utility of noncontact mapping in acute ischemic ventricular fibrillation, by direct comparison with simultaneously acquired multisite contact needle recordings.</AbstractText>Noncontact mapping has emerged as a promising tool to make percutaneous high-density intracardiac electrical r... |
5,268 | Early repolarization syndrome – a new electrical disorder associated with sudden cardiac death –. | Early repolarization (ER), consisting of a J-point elevation, notching or slurring of the terminal portion of the R wave (J wave), and tall/symmetric T wave, is a common finding on the 12-lead electrocardiogram. For decades, it has been considered as benign, barring sporadic case reports and basic electrophysiology res... |
5,269 | Long-term recording of cardiac arrhythmias with an implantable cardiac monitor in patients with reduced ejection fraction after acute myocardial infarction: the Cardiac Arrhythmias and Risk Stratification After Acute Myocardial Infarction (CARISMA) study. | Knowledge about the incidence of cardiac arrhythmias after acute myocardial infarction has been limited by the lack of traditional ECG recording systems to document and confirm asymptomatic and symptomatic arrhythmias. The Cardiac Arrhythmias and Risk Stratification After Myocardial Infarction (CARISMA) trial was desig... |
5,270 | Prognostic impact of atrial fibrillation progression in a community study: AFBAR Study (Atrial Fibrillation in the Barbanza Area Study). | The aim of the study is to describe the natural history of an unselected population of patients with atrial fibrillation (AF) currently attending primary care services in a single health-service area in Galicia, north-western Spain.</AbstractText>AFBAR is a transverse prospective study in which 35 general practitioners... |
5,271 | [Overlooked Wolff-Parkinson-White syndrome]. | An autopsy in a 28-year-old man did not explain the cause of sudden unexpected death. However, a history of episodes with tachycardia and dizziness and a reassessed previous electrocardiogram exhibiting ventricular pre-excitation was consistent with Wolff-Parkinson-White (WPW) syndrome. In this patient we believe that ... |
5,272 | Ventricular arrhythmia is predicted by sum absolute QRST integralbut not by QRS width. | There is a controversy regarding the association between QRS width and ventricular arrhythmias (VAs). We hypothesized that predictive value of the QRS width could be improved if QRS width were considered in the context of the sum magnitude of the absolute QRST integral in 3 orthogonal leads sum absolute QRST integral (... |
5,273 | Short-term autonomic denervation of the atria using botulinum toxin. | Major epicardial fat pads contain cardiac ganglionated plexi (GP) of the autonomic nervous system. Autonomic denervation may improve the success rate of atrial fibrillation (AF) ablation. This study was designed to elucidate the acute effects of blocking the right atrium-pulmonary vein (RA-PV) and left atrium-inferior ... |
5,274 | Assessment of atrial electromechanical delay by tissue Doppler echocardiography in obese subjects. | Our aim was to evaluate whether atrial electromechanical delay measured by tissue Doppler imaging (TDI), which is an early predictor of atrial fibrillation (AF) development, is prolonged in obese subjects. A total of 40 obese and 40 normal-weight subjects with normal coronary angiograms were included in this study. P-w... |
5,275 | Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies. | The aim of this investigation was to estimate and contrast the global incidence and outcome of out-of-hospital cardiac arrest (OHCA) to provide a better understanding of the variability in risk and survival of OHCA.</AbstractText>We conducted a review of published English-language articles about incidence of OHCA, avai... |
5,276 | Hypokalemia during the cooling phase of therapeutic hypothermia and its impact on arrhythmogenesis. | Mild to moderate therapeutic hypothermia (TH) has been shown to improve survival and neurological outcome in patients resuscitated from out-of-hospital cardiac arrest (OHCA) with ventricular fibrillation (VF) as the presenting rhythm. This approach entails the management of physiological variables which fall outside th... |
5,277 | Cardiac herniation following completion pneumonectomy for bronchiectasis. | Sporadic reports on cardiac herniation are available in the literature; most of them had followed intrapericardial pneumonectomies for malignant pulmonary tumors. We present an uncommon event of heart herniation after a completion pneumonectomy indicated for chronic bronchiectasis. A 35-year-old male patient was operat... |
5,278 | Therapeutic hypothermia following out-of-hospital cardiac arrest; does it start in the emergency department? | The use of therapeutic hypothermia after cardiac arrest is a well-practised treatment modality in the intensive care unit (ICU). However, recent evidence points to advantages in starting the cooling process as soon as possible after the return of spontaneous circulation (ROSC). There are no data on implementation of th... |
5,279 | Low-dose diltiazem in atrial fibrillation with rapid ventricular response. | Diltiazem is one of the most commonly used medications to control the rapid ventricular response in atrial fibrillation (AF). The recommended starting dose is an intravenous bolus of 0.25 mg/kg over 2 minutes. To avoid hypotension, we have empirically used a lower dose of diltiazem. We compared the efficacy and safety ... |
5,280 | Effects of norepinephrine on kidney in a swine model of cardiopulmonary resuscitation. | The aim of this study was to study the effects of norepinephrine (NE)-induced hypertension (HT) on renal biochemistry, enzymology, and morphology after restoration of spontaneous circulation (ROSC) by cardiopulmonary resuscitation (CPR) in swine.</AbstractText>After 4 minutes of ventricular fibrillation, standard CPR w... |
5,281 | Abdominal compressions do not achieve similar survival rates compared with chest compressions: an experimental study. | The aim of this study is to investigate whether abdominal compression cardiopulmonary resuscitation (CPR) would result in similar survival rates and neurologic outcome than chest compression CPR in a swine model of cardiac arrest.</AbstractText>Forty Landrace/Large White piglets were randomized into 2 groups: group A (... |
5,282 | Emergent precordial percussion revisited--pacing the heart in asystole. | Precordial percussion is a technique by which a manual force is applied repeatedly to the chest of a patient experiencing an unstable bradycardic or asystolic rhythm. The force is used not to defibrillate the myocardium as is the case with the "precordial thump" in pulseless ventricular tachycardia/ventricular fibrilla... |
5,283 | Radiofrequency energy induced ventricular fibrillation in a case of idiopathic premature ventricular contraction originating from the left ventricular papillary muscle. | A 15-year-old boy without structural heart disease was admitted for the treatment of frequent episodes of premature ventricular contractions (PVCs). Left ventricular mapping revealed that the origin of PVC was at the posterior papillary muscle. Diastolic small potentials were observed during sinus rhythm with a constan... |
5,284 | Prophylactic implantable defibrillator in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia and no prior ventricular fibrillation or sustained ventricular tachycardia. | The role of implantable cardioverter-defibrillator (ICD) in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia and no prior ventricular fibrillation (VF) or sustained ventricular tachycardia is an unsolved issue.</AbstractText>We studied 106 consecutive patients (62 men and 44 women; age, 35.6±... |
5,285 | Assessment of left atrial volume: a focus on echocardiographic methods and clinical implications. | Left atrial enlargement is an important predictor of cardiovascular events such as atrial fibrillation, stroke, heart failure and mortality. A number of methods of left atrial size assessment by echocardiography have been reported, from the simple antero-posterior diameter in the parasternal long axis view to the more ... |
5,286 | Gender difference of clinical characteristics in Chinese patients with spontaneous variant angina. | Spontaneous attack of variant angina (VA) is a unique component of coronary artery disease (CAD), and associated with severe cardiac events. However, no data are available regarding sex differences in Chinese patients with spontaneous attacks of VA. Accordingly, the present retrospective study was initiated to evaluate... |
5,287 | Nifekalant hydrochloride terminating sustained ventricular tachycardia accompanied with QT dispersion prolongation. | Ventricular tachycardia (VT) and ventricular fibrillation are the main reasons causing sudden cardiac death. This study aimed to investigate the effects of nifekalant hydrochloride (NIF) on QT dispersion (QTd) in treating VT.</AbstractText>A total of 16 consecutive patients suffered sustained VT was included and then r... |
5,288 | Characteristics and risk factors of cerebrovascular accidents after percutaneous coronary interventions in patients with history of stroke. | Percutaneous coronary intervention (PCI) is a well-established method for managing coronary diseases. However, the increasing use of PCI has led to an increased incidence of acute cerebrovascular accidents (CVA) related to PCI. In this study, we investigated the characteristics and risk factors of CVA after PCI in pati... |
5,289 | A case of commotio cordis caused by steering wheel injury. | We report a rare case of commotio cordis caused by traffic injury. The patient was a 60-year-old female driver who suffered severe steering wheel impact to the chest during a head-on collision in which her car overturned. She had no history of cardiac disease. Emergency medical services arrived at the scene within 12 m... |
5,290 | Hypoxia causes connexin 43 internalization in neonatal rat ventricular myocytes. | Gap junctions produce low resistance pathways between cardiomyocytes and are major determinants of electrical conduction in the heart. Altered distribution and function of connexin 43 (Cx43), the major gap junctional protein in the ventricles, can slow conduction, and thus contribute to arrhythmogenesis in experimental... |
5,291 | An impaired renal function and advanced heart failure represent independent predictors of the incidence of malignant ventricular arrhythmias in patients with an implantable cardioverter/defibrillator for primary prevention. | Malignant ventricular arrhythmias and inappropriate therapies represent unsolved problems in patients with implantable cardioverter/defibrillator (ICD) for primary prevention. This study focuses on the incidence of such therapies and thereby seeks to identify new predictors of adverse events to enhance risk stratificat... |
5,292 | Sex differences in cardiac injury after severe haemorrhage and ventricular fibrillation in pigs. | Experimental studies have shown sex differences in haemodynamic response and outcome after trauma and haemorrhagic shock. We recently reported that female sex protects against cerebral injury after exsanguination cardiac arrest (CA), independent of sexual effects of hormones. The current study examines if female sex is... |
5,293 | Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death. | L-type calcium channel (LTCC) mutations have been associated with Brugada syndrome (BrS), short QT (SQT) syndrome, and Timothy syndrome (LQT8). Little is known about the extent to which LTCC mutations contribute to the J-wave syndromes associated with sudden cardiac death.</AbstractText>The purpose of this study was to... |
5,294 | Implantable cardioverter defibrillator therapy for congenital long QT syndrome: a single-center experience. | Long QT syndrome's (LQTS) marked heterogeneity necessitates both evidence-based and individualized therapeutic approaches.</AbstractText>This study sought to analyze a single LQTS specialty center's experience regarding the relationship between risk factors and appropriate ventricular fibrillation (VF)-terminating ther... |
5,295 | Sequential algorithm for life threatening cardiac pathologies detection based on mean signal strength and EMD functions. | Ventricular tachycardia (VT) and ventricular fibrillation (VF) are the most serious cardiac arrhythmias that require quick and accurate detection to save lives. Automated external defibrillators (AEDs) have been developed to recognize these severe cardiac arrhythmias using complex algorithms inside it and determine if ... |
5,296 | The use of transtelephonic loop recorders for the assessment of symptoms and arrhythmia recurrence after radiofrequency catheter ablation. | Radiofrequency catheter ablation (RFA) is an effective treatment of arrhythmias. However, patients often remain symptomatic after the procedure. We aimed to assess the arrhythmia recurrence after successful RFA in relation to patients' symptoms using transtelephonic loop recorders. Thirty-six consecutive patients (age ... |
5,297 | The atria: from morphology to function. | The fact that some atrial and ventricular disorders (e.g., atrial fibrillation and heart failure) have a structural basis and cause atrial myocardial remodeling has led to increasing attention being paid to the atrial chambers. Furthermore, the rapid development of mapping and ablative procedures as a means of diagnosi... |
5,298 | Idiopathic ventricular fibrillation controlled successfully with phenytoin. | We describe a case of an individual with idiopathic ventricular fibrillation whose arrhythmias were successfully controlled with phenytoin therapy. |
5,299 | Bivalirudin use during radiofrequency catheter ablation procedures in two patients with a history of heparin-induced thrombocytopenia. | Current guidelines recommend using bivalirudin, a direct thrombin inhibitor,as a preferred alternative to unfractionated heparin in patients with heparin induced thrombocytopenia (HIT) for percutaneous coronary intervention, as well as for cardiac and vascular surgery. Anticoagulation during radiofrequency catheter abl... |
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