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5,100 | Biomarkers in atrial fibrillation, ventricular arrhythmias, and sudden cardiac death. | Cardiac arrhythmias including atrial fibrillation, ventricular tachycardia, and ventricular fibrillation are important causes of cardiovascular morbidity and mortality. Although they usually occur in the setting of structural heart disease, these arrhythmias can be the primary manifestation of subclinical cardiovascula... |
5,101 | Safety and performance of a system specifically designed for selective site pacing. | In the right ventricle, selective site pacing (SSP) has been shown to avoid detrimental hemodynamic effects induced by right ventricular apical pacing and, in the right atrium, to prevent the onset of atrial fibrillation and to slow down disease progression. The purpose of our multicenter observational study was to des... |
5,102 | Dynamic QT/RR relationship in post-myocardial infarction patients with and without cardiac arrest. | Changes in QT interval dynamicity may be associated with susceptibility to ventricular fibrillation (VF) after myocardial infarction (MI). We tested the hypothesis that dynamic QT/RR relationship might differ between post-MI patients with and without a history of VF. We also evaluated the influence of negative T-waves ... |
5,103 | Emergency medical services transport decisions in posttraumatic circulatory arrest: are national practices congruent? | To catalog the 9-1-1 emergency medical services (EMS) transport practices for posttraumatic circulatory arrest patients (PTCAPs) in the majority of the nation's largest municipalities and to compare those practices to guidelines recommended by the National Association of EMS Physicians (NAEMSP) and American College of ... |
5,104 | History and current trends in sudden cardiac arrest and resuscitation in adults. | Cardiac arrest occurs when organized cardiac contractility ceases and circulation stops. During cardiac arrest, electrical activity may be abnormal or absent, and the rhythm documented can be ventricular fibrillation, pulseless ventricular tachycardia, pulseless electrical activity, or asystole. It has been estimated t... |
5,105 | Usefulness of tissue Doppler imaging to predict arrhythmic events in adults with repaired tetralogy of Fallot. | Adults with repaired tetralogy of Fallot (TOF) may be at risk for progressive right ventricular (RV) dilatation and dysfunction, which is commonly associated with arrhythmic events. In frequently volume-overloaded patients with congenital heart disease, tissue Doppler imaging (TDI) is particularly useful for assessing ... |
5,106 | Emerging clinical role of ranolazine in the management of angina. | Chronic stable angina is an exceedingly prevalent condition with tremendous clinical, social, and financial implications. Traditional medical therapy for angina consists of beta-blockers, calcium channel blockers, and nitrates. These agents decrease myocardial oxygen demand and ischemia by reducing heart rate, lowering... |
5,107 | Predisposing factors and incidence of newly diagnosed atrial fibrillation in an urban African community: insights from the Heart of Soweto Study. | Little is known about the incidence and clinical characteristics of newly diagnosed atrial fibrillation/flutter (AF) in urban Africans in epidemiological transition.</AbstractText>This observational cohort study was carried out in the Chris Hani Baragwanath Hospital in Soweto South Africa. A clinical registry captured ... |
5,108 | Factors associated with pulseless electric activity versus ventricular fibrillation: the Oregon sudden unexpected death study. | Corresponding with a continuing decline in the prevalence of sudden cardiac arrest cases presenting with ventricular fibrillation (VF), there has been a significant rise in the prevalence of pulseless electrical activity (PEA). Given significantly lower survival from PEA versus VF, we comprehensively investigated PEA c... |
5,109 | Role of family history of sudden death in risk stratification and prevention of sudden death with implantable defibrillators in hypertrophic cardiomyopathy. | The selection of patients with hypertrophic cardiomyopathy (HC) for the primary prevention of sudden death (SD) with implantable cardioverter-defibrillators (ICDs) has been determined by the assessment of 5 risk factors. We examined one of these markers, the family history of HC-related SD in first-degree relatives, fo... |
5,110 | Dronedarone for the treatment of atrial fibrillation and atrial flutter. | This paper presents a summary of the evidence review group (ERG) report on the clinical effectiveness and cost-effectiveness of dronedarone for the treatment of atrial fibrillation (AF) or atrial flutter based upon a review of the manufacturer's submission to the National Institute for Health and Clinical Excellence (N... |
5,111 | Dronedarone for atrial fibrillation? | Atrial fibrillation (AF) is the commonest sustained heart arrhythmia and is associated with significant morbidity and mortality, with, for example, one in five of all strokes being attributable to the condition. Dronedarone (pronounced dro-ne-da-roan) (Multaq--sanofi-aventis) is a new anti-arrhythmic drug related to th... |
5,112 | Effect of early changes in functional geometry of left ventricular contraction on the development of ventricular fibrillation during acute myocardial ischaemia. An experimental study. | The early appearance of ventricular fibrillation (VF) following acute myocardial infarction (MI) is associated with adrenergic effects and electrical interactions although some early "mechanical" changes may also occur. The aim of the present experimental study was to examine whether early changes in the functional geo... |
5,113 | [Viable myocardium detecting by CARTO voltage mapping in swine model of acute myocardial infarction]. | To evaluate the accuracy and practicability of detecting viable myocardium by CARTO voltage mapping in swine model of acute myocardial infarction (MI).</AbstractText>MI was induced in 13 anesthetized swines via occluding the distal of left anterior descending coronary arteries by angioplasty balloon for 60-90 minutes. ... |
5,114 | Prognostic value of serial B-type natriuretic peptide measurement in asymptomatic organic mitral regurgitation. | Optimal timing of surgery is crucial in mitral regurgitation (MR) to avoid excess mortality and morbidity. The role of brain-type natriuretic peptide (BNP) in this setting remains controversial. We evaluated the value of serial BNP measurements for early prediction of deterioration in asymptomatic MR.</AbstractText>Eig... |
5,115 | Radiofrequency ablation for persistent atrial fibrillation in patients with advanced heart failure and severe left ventricular systolic dysfunction: a randomised controlled trial. | To determine whether or not radiofrequency ablation (RFA) for persistent atrial fibrillation in patients with advanced heart failure leads to improvements in cardiac function.</AbstractText>Patients were recruited from heart failure outpatient clinics in Scotland.</AbstractText>Patients with advanced heart failure and ... |
5,116 | Heart rhythm disturbances in the neonatal alloxan-induced diabetic rat. | Diabetic patients show a higher incidence of cardiac arrhythmias, including ventricular fibrillation and sudden death. Their electrocardiograms may show several alterations from normal patterns, many of them related to the QT. Various diastolic and systolic abnormalities are frequently reported in diabetic patients, an... |
5,117 | Does prearrest adrenergic integrity affect pressor response? A comparison of epinephrine and vasopressin in a spontaneous ventricular fibrillation swine model. | Coronary perfusion pressure (CPP) during resuscitation from cardiac arrest has been shown to correlate with return of spontaneous circulation. Adrenergic blockade of beta-1 and alpha-1 receptors is common in the long-term management of ischemic heart disease and congestive heart failure. We sought to compare the CPP re... |
5,118 | SCN5A mutation is associated with early and frequent recurrence of ventricular fibrillation in patients with Brugada syndrome. | Mutations in SCN5A are reportedly linked to Brugada syndrome (BS), but recent observations suggest that they are not necessarily associated with ventricular fibrillation (VF) in BS patients. Therefore, the clinical importance of SCN5A mutations in BS patients was examined in the present study.</AbstractText> The... |
5,119 | Real-time lesion assessment using a novel combined ultrasound and radiofrequency ablation catheter. | Assessment of lesion size and transmurality is currently via indirect measures. Real-time image assessment may allow ablation parameters to be titrated to achieve transmurality and reduce recurrences due to incomplete lesions.</AbstractText>The purpose of this study was to visualize lesion formation in real time using ... |
5,120 | Modeling the effect of Kv1.5 block on the canine action potential. | A wide range of ion channels have been considered as potential targets for pharmacological treatment of atrial fibrillation. The Kv1.5 channel, carrying the I(Kur) current, has received special attention because it contributes to repolarization in the atria but is absent or weakly expressed in ventricular tissue. The d... |
5,121 | Dronedarone: evidence supporting its therapeutic use in the treatment of atrial fibrillation. | Dronedarone, a benzofuran derivative with a structure similar to amiodarone, has been developed as a potential therapy for patients with atrial fibrillation.</AbstractText>To review the published evidence regarding the efficacy and safety of dronedarone use in patients with atrial fibrillation.</AbstractText>Available ... |
5,122 | Distinct restitution properties in vagally mediated atrial fibrillation and six-hour rapid pacing-induced atrial fibrillation. | The atrial potential duration (APD) restitution has been suggested to play an important role in ventricular fibrillation; however, its role in atrial fibrillation (AF) has not been determined. This study sought to investigate the APD restitution properties in two different AF models: vagally mediated AF and 6-h rapid a... |
5,123 | Control of action potential duration alternans in canine cardiac ventricular tissue. | Cardiac electrical alternans, characterized by a beat-to-beat alternation in action potential waveform, is a naturally occurring phenomenon, which can occur at sufficiently fast pacing rates. Its presence has been putatively linked to the onset of cardiac reentry, which is a precursor to ventricular fibrillation. Previ... |
5,124 | Coronary artery bypass graft for anomalous right coronary artery. | A 27-year-old man with anomalous right coronary artery (RCA) presented with ventricular fibrillatory arrest. Computed tomography angiography revealed an anomalous RCA arising from the left sinus of Valsalva with an acute angulation at the coronary takeoff and compressed interarterial segment. This patient underwent a s... |
5,125 | Utility of postoperative testing of implantable cardioverter-defibrillators. | Implantable cardioverter-defibrillators (ICDs) can provide life-saving therapies for ventricular arrhythmias. Arrhythmia induction and defibrillation threshold testing is often performed at implantation and postoperatively during long-term follow-up to ensure proper device function.</AbstractText>We sought to evaluate ... |
5,126 | Greater three-dimensional ventricular lead tip separation is associated with improved outcome after cardiac resynchronization therapy. | Effective cardiac resynchronization therapy (CRT) is more likely with widely separated left ventricular (LV) and right ventricular (RV) pacing leads tips. We hypothesized that lead separation is an important factor in determining the clinical response to CRT.</AbstractText>A retrospective study of 86 consecutive patien... |
5,127 | Termination of ventricular tachycardia by far-field stimulation in humans: a feasibility study. | Although a low-energy cardioversion (LEC) shock from an implantable cardioverter-defibrillator (ICD) can terminate ventricular tachycardia (VT), it frequently triggers ventricular fibrillation (VF) and is therefore not used in clinical practice. We tested whether a modified LEC shock with a very short duration (0.12-0.... |
5,128 | Outcome of heart failure with preserved ejection fraction: a multicentre spanish registry. | Studies on clinical features, treatment and prognosis of patients with congestive heart failure (CHF) and preserved left ventricular ejection fraction (LVEF) are few and their results frequently conflicting.</AbstractText>To investigate the characteristics and long term prognosis of patients with CHF and preserved (&#x... |
5,129 | Echocardiographic Brockenbrough-Braunwald-Morrow sign. | The Brockenbrough-Braunwald-Morrow sign is the paradoxical decrease in pulse pressure during the post-extrasystole beat seen in patients with hypertrophic obstructive cardiomyopathy. We present a case of intermittent left ventricular outflow tract obstruction and secondary mitral regurgitation resulting from post-extra... |
5,130 | Accurate estimation of entropy in very short physiological time series: the problem of atrial fibrillation detection in implanted ventricular devices. | Entropy estimation is useful but difficult in short time series. For example, automated detection of atrial fibrillation (AF) in very short heart beat interval time series would be useful in patients with cardiac implantable electronic devices that record only from the ventricle. Such devices require efficient algorith... |
5,131 | Improving safety in the electrophysiology laboratory using a simple radiation dose reduction strategy: a study of 1007 radiofrequency ablation procedures. | The use of fluoroscopic screening involves exposure to ionising radiation for both patients and operators.</AbstractText>To assess the effects of radiation dose reduction manoeuvres (DRM) during radiofrequency ablation (RFA) procedures.</AbstractText>Prospective study of DRM.</AbstractText>Tertiary cardiac centre. Inte... |
5,132 | The association between intra-arrest therapeutic hypothermia and return of spontaneous circulation among individuals experiencing out of hospital cardiac arrest. | Therapeutic hypothermia has been shown to improve both mortality and neurologic outcomes following pulseless ventricular tachycardia and fibrillation. Animal data suggest intra-arrest induction of therapeutic hypothermia (IATH) improves frequency of return of spontaneous circulation (ROSC). Our objective was to evaluat... |
5,133 | Novel intravascular defibrillator: defibrillation thresholds of intravascular cardioverter-defibrillator compared to conventional implantable cardioverter-defibrillator in a canine model. | An intravascular, percutaneously placed implantable defibrillator (InnerPulse percutaneous intravascular cardioverter-defibrillator [PICD]) with a right ventricular (RV) single-coil lead and titanium electrodes in the superior vena cava (SVC) and the inferior vena cava (IVC) has been developed.</AbstractText>The purpos... |
5,134 | Potential proarrhythmic effect of cardiac resynchronization therapy during perioperative period: data from a single cardiac center. | Cardiac resynchronization therapy (CRT) could improve heart function, symptom status, quality of life and reduce hospitalization and mortality in patients with severe heart failure (HF) with optimal medical management. However, the possible adverse effects of CRT are often ignored by clinicians.</AbstractText>A retrosp... |
5,135 | Flash pulmonary edema in patients with renal artery stenosis--the Pickering Syndrome. | We report the prevalence of flash pulmonary edema in patients consecutively referred for balloon angioplasty of uni- or bilateral renal artery stenosis (PTRA), and describe the characteristics of this special fraction of the patients. We further report two unusual cases.</AbstractText>Review of medical records from 60 ... |
5,136 | [Restitution of atrial repolarization and atrial fibrillation in canine atrium]. | Electrical restitution was believed to be a determinant responsible for the stability of heart rhythm. Although numerous studies focused on the role of action potential duration restitution (APDR) in the initiation and maintenance of ventricular fibrillation (VF), the relationship between atrial APDR and atrial fibrill... |
5,137 | Transaortic endoclamp for mitral valve operation through right minithoracotomy in 369 patients. | : The effects and benefits of a transaortic endoclamp for mitral valve operation through right minithoracotomy have not been established.</AbstractText>: The records were examined in 671 patients undergoing mitral valve operation using aortic cannulation through a 6-cm right minithoracotomy in the fourth intercostal sp... |
5,138 | Augmented ST-segment elevation during recovery from exercise predicts cardiac events in patients with Brugada syndrome. | The goal of this study was to evaluate the prevalence and the clinical significance of ST-segment elevation during recovery from exercise testing.</AbstractText>During recovery from exercise testing, ST-segment elevation is reported in some patients with Brugada syndrome (BrS).</AbstractText>Treadmill exercise testing ... |
5,139 | Meta-analysis of the effectiveness and safety of catheter ablation of atrial fibrillation in patients with versus without left ventricular systolic dysfunction. | Catheter ablation is a promising therapy for atrial fibrillation (AF), but its utility in patients with left ventricular systolic dysfunction (LVSD) is uncertain. The objectives of this study were to perform a systematic review and meta-analysis of randomized and observational studies comparing the rates of recurrent A... |
5,140 | Usefulness of vernakalant hydrochloride injection for rapid conversion of atrial fibrillation. | The objective of the present study was to assess the safety and effectiveness of vernakalant hydrochloride injection (RSD1235), a novel antiarrhythmic drug, for the conversion of atrial fibrillation (AF) or atrial flutter to sinus rhythm (SR). Patients with either AF or atrial flutter were randomized in a 1:1 ratio to ... |
5,141 | [Summary of the practice guideline 'Atrial fibrillation' (first revision) from the Dutch College of General Practitioners]. | The revised practice guideline 'Atrial fibrillation' from the Dutch College of General Practitioners provides the general practitioner with guidelines for diagnosis and management of patients with atrial fibrillation. To find patients with atrial fibrillation, it is advised to check cardiac rhythm at every blood pressu... |
5,142 | Manual versus mechanical cardiopulmonary resuscitation. An experimental study in pigs. | Optimal manual closed chest compressions are difficult to give. A mechanical compression/decompression device, named LUCAS, is programmed to give compression according to the latest international guidelines (2005) for cardiopulmonary resuscitation (CPR). The aim of the present study was to compare manual CPR with LUCAS... |
5,143 | Noninvasive detection of left-ventricular systolic dysfunction by acoustic cardiography in atrial fibrillation. | Objectives. Assessment of left ventricular (LV) systolic function in patients with atrial fibrillation can be difficult. Acoustic cardiography provides several parameters for quantifying LV systolic function. We evaluated the ability of acoustic cardiography to detect LV systolic dysfunction in patients with and withou... |
5,144 | Brugada syndrome associated with supraventricular tachycardia: diagnostic and therapeutic strategies. | We report the case of a patient with Brugada syndrome and a history of palpitations who presented with an episode of syncope and developed supraventricular tachycardia in the electrophysiological study. The patient was treated with radiofrequency ablation for the supraventricular tachycardia and an implantable cardiove... |
5,145 | Risk stratification in individuals with the Brugada type 1 ECG pattern without previous cardiac arrest: usefulness of a combined clinical and electrophysiologic approach. | Risk stratification in individuals with type 1 Brugada electrocardiogram (ECG) pattern (type 1 ECG) for primary prevention of sudden death (SD).</AbstractText>Three hundred and twenty patients (258 males, median age 43 years) with type 1 ECG were enrolled. No patient had previous cardiac arrest. Fifty-four per cent of ... |
5,146 | [Changes in myocardial connexin 43 during ventricular fibrillation]. | To observe changes in connexin 43 (Cx43) after ventricular fibrillation (VF) and the effects of rotigaptide (ZP123) on Cx43.</AbstractText>Thirty domestic pigs were randomly assigned to three groups (10 in each group): sham group, model group and ZP123 group. VF was induced by an 80 V AC transthoracic shock for 5 secon... |
5,147 | Intracoronary autologous CD34+ stem cell therapy for intractable angina. | <AbstractText Label="BACKGROUND/OBJECTIVES" NlmCategory="OBJECTIVE">A large number of patients with coronary artery disease experience angina that is not suitable for revascularization and is refractory to conventional medical therapy. Laboratory and preclinical studies have provided evidence for the safety and potenti... |
5,148 | Chronic occlusion of the left main coronary artery: importance of collaterals. | Chronic occlusion of the left coronary artery is an infrequent finding in patients undergoing coronary angiography. These patients usually present symptoms of angina or heart failure. We describe a patient who was training regularly without cardiac symptoms until ventricular fibrillation suddenly occurred during a long... |
5,149 | Comparison between transcatheter and surgical prosthetic valve implantation in patients with severe aortic stenosis and reduced left ventricular ejection fraction. | Patients with severe aortic stenosis and reduced left ventricular ejection fraction (LVEF) have a poor prognosis with conservative therapy but a high operative mortality when treated surgically. Recently, transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement (... |
5,150 | Ventricular fibrillation with diminished internal mammary artery graft flow during sternal retraction. | Ventricular fibrillation is a common arrhythmia encountered after the termination of cardiopulmonary bypass. Risk is augmented in patients who are undergoing repeat cardiac procedures with most documented complications occurring during repeat sternotomy. Aortic valve surgery is more complex after coronary artery bypass... |
5,151 | Pulseless electrical activity in cardiac arrest: electrocardiographic presentations and management considerations based on the electrocardiogram. | Pulseless electrical activity (PEA), a cardiac arrest rhythm scenario with an associated poor prognosis, is defined as cardiac electrical activity without a palpable pulse. Considering both outpatient and inpatient cardiac arrest presentations, PEA as a rhythm group has been increasing over the past 10 to 20 years with... |
5,152 | A dangerous fruit juice. | We report the case of a female patient presenting to the emergency department with postprandial syncope and atrial fibrillation. After amiodarone administration, the electrocardiogram showed marked QT prolongation associated with ventricular arrhythmias, including an episode of torsade de pointes requiring immediate el... |
5,153 | Termination of sustained atrial flutter and fibrillation using low-voltage multiple-shock therapy. | Defibrillation therapy for atrial fibrillation (AF) and flutter (AFl) is limited by pain induced by high-energy shocks. Thus, lowering the defibrillation energy for AFl/AF is desirable.</AbstractText>In this study we applied low-voltage multiple-shock defibrillation therapy in a rabbit model of atrial tachyarrhythmias ... |
5,154 | Immediate and 6-month outcomes of transapical and transfemoral Edwards-Sapien prosthesis implantation in patients with aortic stenosis. | severe symptomatic aortic valve stenosis is an unequivocal indication for surgical valve replacement, assuring symptoms relief and increasing survival. About one third of elderly patients is not being operated due to, among others, high peri-procedural risk and comorbidities. Transcatheter aortic valve implantation (TA... |
5,155 | Predicting atrial fibrillation recurrence with circulating inflammatory markers in patients in sinus rhythm at high risk for atrial fibrillation: data from the GISSI atrial fibrillation trial. | Inflammation may play a significant role in the pathogenesis of atrial fibrillation (AF).</AbstractText>To examine the roles of three systemic inflammatory markers in predicting recurrent AF.</AbstractText>The association between the plasma concentrations of high-sensitivity C reactive protein (hsCRP), interleukin-6 (I... |
5,156 | [Transient apical dysfunction syndrome (Tako-Tsubo) simulating acute myocardial infarction]. | Transient apical dysfunction syndrome (TADS) is frequently misdiagnosed as an acute coronary syndrome (ACS). It is characterized by electrocardiographic alterations and elevated myocardial necrosis markers, accompanied by hypokinesia, akinesia or anteroapical dyskinesia, in absence of significant coronary disorders. It... |
5,157 | Atrial Tachycardias Occurring After Atrial Fibrillation Ablation: Strategies for Mapping and Ablation. | The occurrence of left atrial tachycardias (AT) after catheter ablation for atrial fibrillation (AF) is common, especially after more extensive ablation of persistent AF. These AT are invariably symptomatic and often do not respond to medical therapy. The initial strategy involves ventricular rate control, cardioversio... |
5,158 | Rapid ventricular pacing: a fast, reliable, and safe technique for optimization of image acquisition during rotational angiography for catheter ablation of atrial fibrillation. | Rotational angiography is a novel method for three-dimensional reconstruction of the left atrium and pulmonary veins during catheter ablation for atrial fibrillation, but is still hampered by suboptimal reconstructions in a considerable number of patients. We describe the results of rapid pacing of the right ventricle ... |
5,159 | Is this a philosophic issue? Do patients with drug-induced Brugada type ECG have poor prognosis? (Pro). | Brugada syndrome (BS) has an intermittent or concealed type, which can be unmasked by the sodium (Na(+))-channel-blocker challenge test. The appropriate risk stratification of patients with a drug-induced Brugada-type electrocardiographic (ECG), especially those without a history of syncope or aborted sudden cardiac de... |
5,160 | Low risk for arrhythmic events in asymptomatic patients with drug-induced type 1 ECG. Do patients with drug-induced Brugada type ECG have poor prognosis? (Con). | The type 1 ST-segment elevation is diagnostic for Brugada syndrome (BS) and its presence may sometimes be associated with a high risk of arrhythmic events. The type 1 ECG is also known to be unmasked by administration of sodium-channel blockers in equivocal or suspected cases of BS, and the drug-challenge test is frequ... |
5,161 | The role of pulmonary veins vs. autonomic ganglia in different experimental substrates of canine atrial fibrillation. | Pulmonary vein (PV)-encircling ablation, which is effective in suppressing atrial fibrillation (AF), damages autonomic ganglia near the PV ostia. This study examined the effects of PV isolation (PVI) vs. peri-PV ganglionic plexus ablation (GPA) in two discrete canine AF models: ventricular tachypacing (240 bpm, 2 weeks... |
5,162 | Modification of a hybrid technique for closure of muscular ventricular septal defects in a pig model. | Closure of muscular ventricular septal defects (mVSDs) beyond the moderator band is still a challenge for both surgeons and interventional cardiologists. We evaluated a new technique in a pig model for hybrid patch closure of mVSDs via 2 stab wound incisions in the left ventricle (LV) without cardiopulmonary bypass.</A... |
5,163 | [An autopsy case of senile dementia suspected to be influenced by cerebral amyloid angiopathy with multiple cortical microinfarcts]. | A Japanese male showed gradually progressing dementia with psychiatric symptoms including abnormal behavior, night and day reversal, nocturnal delirium, loud shouting, agitation, resistance to care, and loud soliloquy. The patient had a history of right cerebral embolism due to atrial fibrillation 1 month before the on... |
5,164 | [Successful use of intravenous amiodarone for refractory ventricular fibrillation just after releasing aortic cross-clamp]. | Amiodarone is widely used in Europe and the United States for refractory ventricular fibrillation (VF) in various situations, such as VF after myocardial infarction or out-of-hospital cardiac arrest. We report a case of successful treatment with amiodarone of refractory VF immediately after releasing aortic cross-clamp... |
5,165 | Atrioventricular reverse remodeling after valve repair for chronic severe mitral regurgitation: 1-year follow-up. | Chronic severe mitral regurgitation is associated with poor clinical outcome because chronic volume overload leads to hemodynamic changes and left ventricular and left atrial remodeling. Few data are available regarding left atrial volume index regression (LAVIR) and left ventricular mass index regression (LVMIR) after... |
5,166 | Outcome of invasive electrophysiological procedures and gender: are males and females the same? | The aim of this review is to summarize the available evidence on gender-related differences in outcome of invasive electrophysiological procedures. Gender exerts significant influences on the epidemiology, pathophysiology, and clinical presentation of many cardiac rhythm disorders. Women with supraventricular arrhythmi... |
5,167 | Combining shock reduction strategies to enhance ICD therapy: a role for computer modeling. | To develop a computer model to test shock reduction strategies such as antitachycardia pacing and shock withholding for supraventricular rhythms, oversensing, and nonsustained ventricular tachycardia.</AbstractText>While the implantable cardioverter defibrillator (ICD) can reduce mortality, inappropriate ICD shocks rem... |
5,168 | A case of atrial fibrillation induced by inhaled fluticasone propionate. | Atrial fibrillation (AF) is the most common rhythm disorder observed in clinical practice. Several case reports and case-control studies have associated this condition with the use of systemic corticosteroids. However, to our knowledge, no case of AF induced by inhaled corticosteroids has been reported in the literatur... |
5,169 | Effects of therapeutic hypothermia on coagulopathy and microcirculation after cardiopulmonary resuscitation in rabbits. | The aim of this study was to investigate the effects of therapeutic hypothermia (TH) on coagulopathy and cerebral microcirculation disorder after cardiopulmonary resuscitation (CPR) in rabbits.</AbstractText>Cardiac ventricular fibrillation was induced by alternating current in 24 New Zealand rabbits, and hypothermia w... |
5,170 | A KCR1 variant implicated in susceptibility to the long QT syndrome. | The acquired long QT syndrome (aLQTS) is frequently associated with extrinsic and intrinsic risk factors including therapeutic agents that inadvertently inhibit the KCNH2 K(+) channel that underlies the repolarizing I(Kr) current in the heart. Previous reports demonstrated that K(+) channel regulator 1 (KCR1) diminishe... |
5,171 | Antiarrhythmic and antioxidant activity of novel pyrrolidin-2-one derivatives with adrenolytic properties. | A series of novel pyrrolidin-2-one derivatives (17 compounds) with adrenolytic properties was evaluated for antiarrhythmic, electrocardiographic and antioxidant activity. Some of them displayed antiarrhythmic activity in barium chloride-induced arrhythmia and in the rat coronary artery ligation-reperfusion model, and s... |
5,172 | A major role for HERG in determining frequency of reentry in neonatal rat ventricular myocyte monolayer. | the rapid delayed rectifier potassium current, I(Kr), which flows through the human ether-a-go-go-related (hERG) channel, is a major determinant of the shape and duration of the human cardiac action potential (APD). However, it is unknown whether the time dependency of I(Kr) enables it to control APD, conduction veloci... |
5,173 | Catheter ablation of electrical storm in patients with structural heart disease. | Electrical storm (ES) adversely affects prognosis of patients and may become a life-threatening event. Catheter ablation (CA) has been proposed for the treatment of ES. Our goal was to evaluate the efficacy of CA ablation both in acute and long-term suppression of ES.</AbstractText>Fifty consecutive patients with coron... |
5,174 | New conventional long-term survival normovolemic cardiac arrest pig model. | A reproducible long-term intensive care and outcome cardiac arrest model for exploring new cerebral preservation strategies is needed. We tried to determine effects and limitations of current therapies after different 'no-flow' times.</AbstractText>Thirty-five female Large White Breed pigs (26-37kg) were included in th... |
5,175 | Systemic fibrinolysis through intraosseous vascular access in ST-segment elevation myocardial infarction. | In emergency situations, intraosseous cannulation represents an alternative route of vascular access when peripheral vein insertion is difficult. We present the first documented case of intraosseous systemic fibrinolysis in a patient with ST-segment elevation myocardial infarction. In this case, repetitive episodes of ... |
5,176 | Clinical impact of screening for sleep related breathing disorders in atrial fibrillation. | The aim of this study was to quantify daytime symptoms in atrial fibrillation (AF) patients with and without sleep related breathing disorders (SRBD).</AbstractText>SRBD are common in patients with AF but little is known about daytime symptoms among those with SRBD.</AbstractText>Patients with AF admitted to clinics of... |
5,177 | Clinical and electrophysiological profile of Brugada syndrome in the Tunisian population. | Most clinical studies of the clinical profile of Brugada syndrome (BS) have been conducted in either Asia, Europe, or America and their applicability to North African populations is largely unknown. The aim of the study was to analyze the clinical profile of BS in Tunisian patients.</AbstractText>The clinical and follo... |
5,178 | Failure of transvenous ICD to terminate ventricular fibrillation in a patient with left ventricular noncompaction and polycystic kidneys. | Implantable cardioverter defibrillator (ICD) testing in patients with left ventricular noncompaction (LVNC) at the time of implantation and potential difficulties with ventricular fibrillation (VF) induction/termination in LVNC patients are often not stated in the literature. This report describes the failure of transv... |
5,179 | Clinical predictors of conduction disease progression in type I myotonic muscular dystrophy. | Patients with type I myotonic muscular dystrophy (DM1) are at risk for sudden death due to atrioventricular conduction block. We sought to characterize the trends and predictors of time-dependent electrocardiographic (ECG) variations in patients with DM1.</AbstractText>Seventy patients with DM1 underwent standard elect... |
5,180 | Effect of substance abuse on defibrillation threshold in patients with implantable cardioverter-defibrillator. | The use of recreational drugs has been observed to have deleterious effects on the heart. The aim of our study was to evaluate the effect of substance abuse on the defibrillation threshold (DFT) in patients with implantable cardioverter-defibrillators (ICDs).</AbstractText>A retrospective analysis was conducted on pati... |
5,181 | Contributions of a hemodynamic sensor embedded in an atrial lead in a porcine model. | Preliminary studies have revealed a high correlation between peak endocardial acceleration (PEA) measured with a sensor embedded in a ventricular lead and human cardiac contractility. In this study we assessed (1) the contributions made by measurements of PEA1, an index of ventricular systolic contraction, from the rig... |
5,182 | Temporal associations between thoracic volume overload and malignant ventricular arrhythmias: a study of intrathoracic impedance. | Acute exacerbations of heart failure (HF) are believed to trigger malignant ventricular arrhythmias, but the temporal association between fluid accumulation and ventricular arrhythmias has not been evaluated in an objective manner. We hypothesized that increased intrathoracic fluid accumulation in patients with HF, as ... |
5,183 | Severe vasospastic angina with ventricular fibrillation suggested by iodine-123 beta-methyl-p-iodophenyl-pentadecanoic acid in a young woman. | Iodine-123 beta-methyl-p-iodophenyl-pentadecanoic acid (BMIPP) imaging is useful to diagnose recent myocardial ischemia. A 27-year-old woman was admitted to our hospital because of aborted cardiac arrest due to ventricular fibrillation. She underwent BMIPP imaging in order to rule out ischemic heart disease. Reduced BM... |
5,184 | Spontaneous resolution of sinoatrial exit block and atrioventricular dissociation in a child with dengue fever. | Cardiac rhythm abnormalities, including ventricular arrhythmia, atrial fibrillation and atrioventricular block, have been observed during the acute stage of dengue haemorrhagic fever. Atrioventricular or complete heart block can be fatal and may require a temporary pacemaker. We report a ten-year-old girl who presented... |
5,185 | Pharmacological testing in the diagnosis of arrhythmias. | Pharmacological testing has several indications in the diagnosis of arrhythmia. It is used for the diagnosis of bradycardia-related syncope either during non invasive tests as adenosine triphosphate (ATP) for the diagnosis of vasovagal syncope, but also for the diagnosis of sick sinus syndrome or isoproterenol infusion... |
5,186 | Primary electrical diseases diagnosis, genetic and management. | Primary electrical diseases or channelopathies are inherited genetic alterations of the cell ionic and electrical behavior leading to various cardiac arrhythmias carrying the risk of sudden death. A descriptive review of the successively described channelopathies is made in this article, with emphasis on the clinical m... |
5,187 | Genetic Basis of Ventricular Arrhythmias. | Sudden cardiac death (SCD) is a leading cause of total and cardiovascular mortality, and ventricular fibrillation is the underlying arrhythmia in the majority of cases. In the young, where the incidence of SCD is low, a great proportion of SCDs occur in the context of inherited disorders such as cardiomyopathy or prima... |
5,188 | Successful use of ivabradine in a case of exaggerated autonomic dysfunction. | We present a 30-year-old male with complex and predominantly cardiovascular autonomic dysfunction. He had frequent syncopal attacks and paroxysmal atrial fibrillation (PAF). Physical, electrocardiographic, and echocardiographic findings were unremarkable. Syncopal attacks were precipitated by emotional stress, upright ... |
5,189 | Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A review of the Japanese literature. | Although favourable outcomes in patients receiving extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest have been frequently reported in Japanese journals since the late 1980s, there has been no meta-analysis of ECPR in Japan. This study reviewed and analysed all previous studies in Ja... |
5,190 | Cardiac safety of conducted electrical devices in pigs and their effect on pacemaker function. | The aims of this study are to evaluate the cardiac safety of the Stinger S-200 Conducted Energy Weapon Device (CED) (Stinger Systems, Tampa, Fla) on a human-sized pig model and to test the effect of various commercially available CEDs, specifically the Stinger S-200, TASER M26 (Taser International, Scottsdale, Ariz), a... |
5,191 | Pharmacology of cardiac potassium channels. | Cardiac K(+) channels are cardiomyocyte membrane proteins that regulate K(+) ion flow across the cell membrane on the electrochemical gradient and determine the resting membrane potential and the cardiac action potential morphology and duration. Several K(+) channels have been well studied in the human heart. They incl... |
5,192 | The ryanodine receptor in cardiac physiology and disease. | According to the American Heart Association it is estimated that the United States will spend close to $39 billion in 2010 to treat over five million Americans suffering from heart failure. Patients with heart failure suffer from dyspnea and decreased exercised tolerance and are at increased risk for fatal ventricular ... |
5,193 | Right ventricular dysfunction is a strong predictor of developing atrial fibrillation in acutely decompensated heart failure patients, ACAP-HF data analysis. | Heart failure and atrial fibrillation (AFib) are the twin epidemics of modern cardiovascular disease. The incidence of new-onset AFib in acute decompensated heart failure (ADHF) patients is difficult to predict and the short- and long-term outcomes of AFib in a cohort of patients admitted with ADHF are unknown.</Abstra... |
5,194 | Recurrent post-partum coronary artery dissection. | Coronary artery dissection is a rare but well-described cause for myocardial infarction during the post-partum period. Dissection of multiple coronary arteries is even less frequent. Here we present a case of recurrent post-partum coronary artery dissections. This unusual presentation poses unique problems for manageme... |
5,195 | [Comparison of treatment effectiveness of implantable cardioverter defibrillator in patients undergoing defibrillation threshold testing at the time of implantation versus no defibrillation threshold testing]. | Inability to perform defibrillation threshold (DFT) testing during implantable cardioverter defibrillator (ICD) implantation due to comorbidities may influence long-term survival.</AbstractText>Retrospective review (2005-2007) identified 142 patients undergoing ICD implantation without DFT testing (No-DFT group). A con... |
5,196 | Defibrillation in children. | Defibrillation is the only effective treatment for ventricular fibrillation (VF). Optimal methods for defibrillation in children are derived and extrapolated from adult data. VF occurs as the initial rhythm in 8-20% of pediatric cardiac arrests. This has fostered a new interest in determining the optimal technique for ... |
5,197 | Better outcome after pediatric resuscitation is still a dilemma. | Pediatric cardiac arrest is not a single problem. Although most episodes of pediatric cardiac arrest occur as complications and progression of respiratory failure and shock. Sudden cardiac arrest may result from abrupt and unexpected arrhythmias. With a better-tailored therapy, we can optimize the outcome. In the hospi... |
5,198 | Utilization of Electrocardiographic P-wave Duration for AV Interval Optimization in Dual-Chamber Pacemakers. | Empiric programming of the atrio-ventricular (AV) delay is commonly performed during pacemaker implantation. Transmitral flow assessment by Doppler echocardiography can be used to find the optimal AV delay by Ritter's method, but this cannot easily be performed during pacemaker implantation. We sought to determine a no... |
5,199 | Predictors for permanent pacing after transcatheter aortic valve implantation. | Transcatheter aortic valve implantation (TAVI) is a new treatment strategy for patients with symptomatic aortic stenosis who are high risk for traditional surgical aortic valve replacement. The incidence of conduction system abnormalities after the procedure is significant. We examine our experience with CoreValve TAVI... |
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