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5,300 | Premature Ventricular Contractions and Non-sustained Ventricular Tachycardia: Association with Sudden Cardiac Death, Risk Stratification, and Management Strategies. | Premature ventricular contractions (PVCs) and non-sustained ventricular tachycardia (NSVT) are frequently encountered and a marker of electrocardiomyopathy. In some instances, they increase the risk for sustained ventricular tachycardia, ventricular fibrillation, and sudden cardiac death. While often associated with a ... |
5,301 | Anatomic guidance for ablation: atrial flutter, fibrillation, and outflow tract ventricular tachycardia. | After initial documentation of excellent efficacy with radiofrequency ablation, this procedure is being performed increasingly in more complex situations and for more difficult arrhythmia. In these circumstances, an accurate knowledge of the anatomic basis for the ablation procedure will help maintain this efficacy and... |
5,302 | Interference of remote magnetic catheter navigation and ablation with implanted devices for pacing and defibrillation. | Remote magnetic catheter navigation (RMN) may facilitate catheter ablation. However, as the system uses permanent magnets, interference (INF) with devices for pacing [pacemaker (PM)], defibrillation [implantable cardioverter defibrillators (ICD)], or cardiac resynchronisation [cardiac resynchronization therapy (CRT)] m... |
5,303 | Incidence of rearrest after return of spontaneous circulation in out-of-hospital cardiac arrest. | Return of spontaneous circulation (ROSC) occurs in 35.0 to 61.0% of emergency medical services (EMS)-treated out-of-hospital cardiac arrests (OHCAs); however, not all patients achieving ROSC survive to hospital arrival or discharge. Previous studies have estimated the incidence of some types of rearrest(RA) at 61.0 to ... |
5,304 | Delayed time to defibrillation after intraoperative and periprocedural cardiac arrest. | Delay in defibrillation (more than 2 min) is associated with worse survival in patients with a cardiac arrest because of ventricular fibrillation or pulseless ventricular tachycardia in intensive care units and inpatient wards.</AbstractText>We tested the relationship between delayed defibrillation and survival from in... |
5,305 | Prevalence and predictors of pulmonary hypertension in elderly patients with isolated diastolic heart failure. | Despite the growing recognition that pulmonary hypertension can develop in diastolic heart failure; its clinical significance remains poorly defined.</AbstractText>We sought to explore the prevalence and predictors of pulmonary hypertension in elderly patients with isolated diastolic heart failure.</AbstractText>We enr... |
5,306 | Exploring newer cardioprotective strategies: ω-3 fatty acids in perspective. | In the 1980s, observational retrospective studies showed an inverse relation between coronary heart disease (CHD) and consumption of fish containing fatty acids that belong to the omega (ω)-3 family. Large case-control studies and prospective intervention trials consistently showed that ω-3 fatty acids supp... |
5,307 | Time in recurrent ventricular fibrillation and survival after out-of-hospital cardiac arrest. | Current resuscitation guidelines (2005 guidelines [G2005]) accelerate ventricular fibrillation (VF) recurrence. We investigated whether patients resuscitated under G2005 spend more time in VF and have better survival rates than patients treated under the 2000 guidelines (G2000).</AbstractText>We analyzed continuous ECG... |
5,308 | Advances in Antiarrhythmic Drug Therapy: New and Emerging Therapies. | Despite major advances in the nonpharmacologic therapy for arrhythmias in the past decades, there is still a substantial role for antiarrhythmic drugs especially in the treatment of atrial fibrillation and ventricular tachycardia, the most effective of which is amiodarone. Dronedarone has been developed by modifying th... |
5,309 | Acute Antiarrhythmic Therapy of Ventricular Tachycardia and Ventricular Fibrillation. | Ventricular arrhythmias (ventricular tachycardia and ventricular fibrillation) are often associated with underlying structural heart disease and require prompt assessment and treatment. Acute treatment involves initial hemodynamic stabilization of the patient followed by suppressive treatment with pharmacologic and non... |
5,310 | Chronic Maintenance of Sinus Rhythm in Patients with Atrial Fibrillation Using Antiarrhythmic Drugs: Update 2010. | Atrial fibrillation (AF) is a growing public health concern. For most patients the treatment of AF involves antiarrhythmic drugs. Despite the widespread use of antiarrhythmic drugs for the conversion of AF and maintenance of normal sinus rhythm, their use is limited by modest efficacy, frequent intolerance, and the pot... |
5,311 | Complex structure of electrophysiological gradients emerging during long-duration ventricular fibrillation in the canine heart. | Long-duration ventricular fibrillation (LDVF) in the globally ischemic heart is a common setting of cardiac arrest. Electrical heterogeneities during LDVF may affect outcomes of defibrillation and resuscitation. Previous studies in large mammalian hearts have investigated the role of Purkinje fibers and electrophysiolo... |
5,312 | Redo sternotomy for cardiac reoperations using peripheral heparin-bonded cardiopulmonary bypass circuits without systemic heparinization: technique and results. | Cardiac reoperations are challenging and time-consuming and incur a high incidence of perioperative complications because of injuries to cardiac structures, bleeding, and hemodynamic instability. Some centers are using extracorporeal circulation with heparinization at the time of resternotomy, but it leads to prolonged... |
5,313 | One single dose of histidine-tryptophan-ketoglutarate solution gives equally good myocardial protection in elective mitral valve surgery as repetitive cold blood cardioplegia: a prospective randomized study. | Histidine-tryptophan-ketoglutarate (HTK-Custodiol) cardioplegic solution is administered as one single dose for more than 2 hours of ischemia. No prospective randomized clinical study has compared the effects of HTK and cold blood cardioplegia on myocardial damage in elective mitral valve surgery. Thus, the main aim of... |
5,314 | Optimization of Doppler echocardiographic velocity measurements using an automatic contour detection method. | Intra- and interobserver variability in Doppler echocardiographic velocity measurements (DEVM) is a significant issue. Indeed, imprecisions of DEVM can lead to diagnostic errors, particularly in the quantification of the severity of heart valve dysfunctions. To reduce the variability and rapidity of DEVM, we have devel... |
5,315 | Predicting cardiotoxicity propensity of the novel iodinated contrast medium GE-145: Ventricular fibrillation during left coronary arteriography in pigs. | Severe side effects caused by iodinated radiographic contrast media (CM) are rare, but can occur in high risk patients and during percutaneous coronary intervention. To minimize this risk a new nonionic CM with low inherent osmolality has been designed, giving room for a relatively high concentration of favorable elect... |
5,316 | Evaluation of left ventricular dyssynchrony using combined pulsed wave and tissue Doppler imaging. | The combination of pulsed wave (PW) and tissue Doppler imaging (TDI) has been proposed as a new method to assess left ventricular (LV) mechanical dyssynchrony (LVMD), but results have not been validated. We investigated the correlation of a combination of PW and TDI with a positive response to cardiac resynchronization... |
5,317 | Role of ambulance response times in the survival of patients with out-of-hospital cardiac arrest. | To evaluate the role of ambulance response times in improving survival for out-of-hospital cardiac arrest (OHCA).</AbstractText>OHCAs were identified by sampling consecutive life-threatening category A emergency ambulance calls on an annual basis for the 5 years 1996/7-2000/1 from four ambulance services in England. Fr... |
5,318 | Pericardial fat is independently associated with human atrial fibrillation. | The purpose of this study was to investigate the association between atrial fibrillation (AF) and pericardial fat.</AbstractText>Pericardial fat is visceral adipose tissue that possesses inflammatory properties. Inflammation and obesity are associated with AF, but the relationship between AF and pericardial fat is unkn... |
5,319 | Prevalence and predictors of off-label use of cardiac resynchronization therapy in patients enrolled in the National Cardiovascular Data Registry Implantable Cardiac-Defibrillator Registry. | The purpose of the study was to define the extent and nature of cardiac resynchronization therapy (CRT) device usage outside consensus guidelines using national data.</AbstractText>Recent literature has shown that the application of CRT in clinical practice frequently does not adhere to evidence-based consensus guideli... |
5,320 | Dronedarone: a new antiarrhythmic agent. | Dronedarone is an antiarrhythmic agent recently approved by the United States Food and Drug Administration for the reduction of cardiovascular-related hospitalizations in patients with paroxysmal or persistent atrial fibrillation or atrial flutter. The drug is a derivative of amiodarone and has been modified to reduce ... |
5,321 | Defibrillation and resuscitation in a piglet model of pediatric ventricular fibrillation following AHA 2005 guidelines. | To evaluate the efficacy and safety of defibrillation on children according to AHA 2005 recommendations</AbstractText>Pig resembles human in the chest configuration, anatomy and physiology of the cardiovascular and pulmonary systems. Piglets weighing 7.0 Kg ± 1.4kg, 14.0kg ± 2.8kg, 25.0kg ± 5.0kg respect... |
5,322 | Takotsubo cardiomyopathy presenting as postoperative atrial fibrillation. | Takotsubo cardiomyopathy (TC) is a condition which was first acknowledged in Japan and is characterized by a reversible systolic dysfunction of the apical or mid segments of the left ventricle. Typically affecting women in the post-menopausal population, it is triggered by intense emotional, physical or medical stress.... |
5,323 | Automated external defibrillation by first-responders. | This review examines whether the use of automated external defibrillators by first-responders improves the survival of adults who suffer cardiopulmonary arrest. We also examined the risks associated with these devices, based on a review of the literature using the standard Prescrire methodology. Automated external defi... |
5,324 | Survey of the use of therapeutic hypothermia post cardiac arrest. | Therapeutic hypothermia improves neurological outcome in adults after ventricular fibrillation cardiac arrest and neonates with hypoxic ischaemic encephalopathy. There is currently no clinical research to support its use in the paediatric population. This survey aims to ascertain current practice in the UK, and attitud... |
5,325 | Sleep disordered breathing and arrhythmia burden in pacemaker recipients. | Sleep disordered breathing (SDB), a common condition among patients with permanent pacemaker (PM), is associated with greater incidence of cardiac arrhythmias. Scarce availability of sleep laboratories and the high costs of nocturnal-attended polysomnography limit the routine screening of patients with PM for SDB. We i... |
5,326 | ICD defibrillation failure solved in an unusual fashion. | An implantable cardioverter defibrillator (ICD) is designed to sense life-threatening ventricular arrhythmias and terminate them, either by rapid pacing or by delivering an electrical shock. Nowadays it is a proven therapy for both primary and secondary prevention of sudden cardiac death. The typical configuration of a... |
5,327 | Association between clinical examination and outcome after cardiac arrest. | Neurologic prognostication after cardiac arrest relies on clinical examination findings derived before the advent of therapeutic hypothermia (TH). We measured the association between clinical examination findings at hospital arrival, 24, and 72 h after cardiac arrest in a modern intensive care unit setting.</AbstractTe... |
5,328 | Biphasic DC shock cardioverting doses for paediatric atrial dysrhythmias. | To determine cardioversion doses of biphasic DC shock for paediatric atrial dysrhythmias.</AbstractText>Prospective recording of energy, pre-shock and post-shock rhythms.</AbstractText>Paediatric hospital.</AbstractText>Shockable atrial dysrhythmias.</AbstractText>Forty episodes of atrial dysrhythmias among 25 children... |
5,329 | Low risk of major complications associated with pulmonary vein antral isolation for atrial fibrillation: results of 500 consecutive ablation procedures in patients with low prevalence of structural heart disease from a single center. | To report the major complication rate associated with pulmonary vein antral isolation (PVAI) in a consecutive series of 500 patients from a single center.</AbstractText>Catheter ablation for atrial fibrillation (AF) is an established procedure for refractory AF. However, the risk of major complications has been reporte... |
5,330 | High concentrations of B-type natriuretic peptide and left ventricular diastolic dysfunction in patients with paroxysmal/persistent atrial fibrillation as possible markers of conversion into permanent form of arrhythmia: 1-year prospective evaluation. | Atrial fibrillation (AF) may cause electrical and structural atrial remodelling, leading to progression from paroxysmal to permanent form of arrhythmia. Predictors of such a transition have not yet been well established.</AbstractText>To assess the role of B-type natriuretic peptide (BNP) and left ventricular (LV) dias... |
5,331 | Vernakalant, a mixed sodium and potassium ion channel antagonist that blocks K(v)1.5 channels, for the potential treatment of atrial fibrillation. | Despite being the most common arrhythmia currently treated by cardiologists, safe and effective treatments for atrial fibrillation (AF) remain elusive. To address this issue, Astellas Pharma Inc, Merck & Co Inc and Cardiome Pharma Corp are developing vernakalant (RSD-1235), a drug which dose-dependently inhibits so... |
5,332 | Clinical predictors of preserved left ventricular ejection fraction in decompensated heart failure. | Identification and clinical impact of preserved left ventricular ejection fraction (LVEF) on in-hospital outcomes in patients with acute decompensated heart failure (HF) remain poorly defined.</AbstractText>To describe clinical predictors and in-hospital outcomes of acute decompensated HF patients and preserved LVEF, a... |
5,333 | Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia. | Amiodarone has emerged as the leading antiarrhythmic therapy for termination and prevention of ventricular arrhythmia in different clinical settings because of its proven efficacy and safety. In patients with shock refractory out-of-hospital cardiac arrest and hemodynamically destabilizing ventricular arrhythmia, amiod... |
5,334 | Dronedarone in patients with atrial fibrillation. | Dronedarone is a recently developed new class III antiarrhythmic drug which possesses electrophysiological properties of all four Vaughan-Williams classes. An important difference with amiodarone is that it does not contain an iodine component and therefore lacks the iodine-related adverse effects. Based on currently a... |
5,335 | Isolated left ventricular pacing results in worse long-term clinical outcome when compared with biventricular pacing: a single-centre randomized study. | The objective of this study was to compare long-term clinical effects of biventricular pacing with isolated left ventricular pacing.</AbstractText>Forty consecutive patients with idiopathic dilated cardiomyopathy and indication for cardiac resynchronization therapy were randomized to biventricular or isolated left vent... |
5,336 | Defining new insight into atypical arrhythmia: a computational model of ankyrin-B syndrome. | Normal cardiac excitability depends on the coordinated activity of specific ion channels and transporters within specialized domains at the plasma membrane and sarcoplasmic reticulum. Ion channel dysfunction due to congenital or acquired defects has been linked to human cardiac arrhythmia. More recently, defects in ion... |
5,337 | A clinical prediction model to estimate risk for 30-day adverse events in emergency department patients with symptomatic atrial fibrillation. | Atrial fibrillation affects more than 2 million people in the United States and accounts for nearly 1% of emergency department (ED) visits. Physicians have little information to guide risk stratification of patients with symptomatic atrial fibrillation and admit more than 65%. Our aim is to assess whether data availabl... |
5,338 | Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. | Patients with long QT syndrome (LQTS) are at increased risk not only for ventricular arrhythmias but also for atrial pathology including atrial fibrillation (AF). Some patients with "lone" AF carry Na(+)-channel mutations.</AbstractText>The purpose of this study was to determine the mechanisms underlying atrial patholo... |
5,339 | Late potential at the high ventricular septal level in a patient with Brugada: possible mechanisms and clinical implications. | The Brugada syndrome (BS) accounts for approximately 20% of cases of sudden cardiac death in patients with structurally normal hearts. The electrophysiologic basis for ST-segment elevation in the precordial electrocardiogram (ECG) leads that characterize the Brugada phenotype and its strong linkage to ventricular tachy... |
5,340 | Short and long QT syndromes: does QT length really matter? | The short and long QT syndromes are inherited diseases associated with an increased risk for life-threatening arrhythmias. The first case of long QT syndrome (LQTS) was reported more than 150 years ago, and the study of this disease led to crucial advancement of our understanding of channelopathies and associated ventr... |
5,341 | Distribution of neuropathological lesions in pig brains after different durations of cardiac arrest. | To evaluate all brain regions reported to be selectively vulnerable to global ischaemia in a pig cardiac arrest model with different durations of no-flow by establishing a semi-quantitative brain histopathologic scoring system and to compare histological damage with neurological deficits.</AbstractText>In a prospective... |
5,342 | Epicardial left atrial appendage and biatrial appendage accessory pathways. | Acute success rates of accessory pathway ablation for Wolff-Parkinson-White (WPW) syndrome can exceed 95%, with rare failures attributed to anatomically complex epicardial connections. Right atrial appendage to right ventricle pathways have been reported, but their left-sided counterparts have only recently been descri... |
5,343 | Do traditional VT zones improve outcome in primary prevention ICD patients? | We reviewed outcomes in our primary prevention implantable cardioverter defibrillator (ICD) population according to whether the device was programmed with a single ventricular fibrillation (VF) zone or with two zones including a ventricular tachycardia (VT) zone in addition to a VF zone.</AbstractText>This retrospectiv... |
5,344 | Incidence, risk factors, and clinical outcomes of atrial fibrillation and atrial flutter after heart transplantation. | Atrial fibrillation (AF) and atrial flutter (AFL) after heart transplantation (HT) has been associated with increased mortality. Diverse incidence rates have been reported to date, with no clear classification according to the time of onset of such arrhythmias. We determined the incidence of AF/AFL using the time of on... |
5,345 | Atrial arrhythmias in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia and ventricular tachycardia. | Information on atrial arrhythmia associated with right ventricular cardiomyopathy/dysplasia (ARVC/D) is limited. In 36 patients with task force criteria for ARVC/D and history of ventricular tachycardia (VT), we confirmed the incidence and type of atrial arrhythmia, onset related to referral for VT ablation, fastest do... |
5,346 | Effect of cardiac resynchronization therapy on subendo- and subepicardial left ventricular twist mechanics and relation to favorable outcome. | The analysis of left ventricular (LV) mechanics provides novel insights into the effects of cardiac resynchronization therapy (CRT) on LV performance. Currently, advances in speckle-tracking echocardiographic analysis have permitted the characterization of subendocardial and subepicardial LV twist. The aim of this stud... |
5,347 | Comparison of detection of arrhythmias in patients with chronic heart failure secondary to non-ischemic versus ischemic cardiomyopathy by 1 versus 7-day holter monitoring. | The purpose of this study was to compare the diagnostic sensitivity of 1-day Holter monitoring versus 7-day Holter monitoring (7DH) to detect atrial and ventricular arrhythmias in a population of stable patients with chronic heart failure and left ventricular dysfunction. Sixty-three consecutive stable patients with ch... |
5,348 | Effect of high doses of magnesium on converting ibutilide to a safe and more effective agent. | Ibutilide is a class III antiarrhythmic agent indicated for cardioversion of atrial fibrillation and atrial flutter to sinus rhythm (SR). The most serious complication of ibutilide is torsades de pointes (TdP). Magnesium has been successfully used for the treatment of TdP, but its use as a prophylactic agent for this a... |
5,349 | Hemiazygous coil placement for high-defibrillation thresholds in a patient with a right-sided implantable cardioverter defibrillator. | A 41-year-old man underwent implantation of a right-sided implantable cardioverter defibrillator after removal of an infected left-sided system. Defibrillation threshold (DFT) testing on the right-sided system failed to convert ventricular fibrillation at maximum device output (35 J) compared with a DFT of less than 15... |
5,350 | Implantation of a fully subcutaneous ICD in children. | The subcutaneous implantable cardioverter defibrillator (S-ICD) from Cameron Health (San Clemente, CA, USA) does not require a lead to be placed on or in the heart. Such a device, being subcutaneous, has potential benefits in children who require ICDs where problems largely relate to transvenous or epicardial leads and... |
5,351 | An acute myocardial infarction case that survived an out-of-hospital cardiac arrest in which prominent ischemic J waves were documented. | We describe a case of a myocardial infarction, in which prominent ischemic J waves were documented during recurrent ventricular fibrillation attacks. The patient was referred to our hospital to treat an out-of hospital cardiac arrest. Although the 12-lead electrocardiogram obtained just after the first cardioversion di... |
5,352 | Significant impairment of left atrial function in patients with cardioembolic stroke caused by paroxysmal atrial fibrillation. | Patients with cardioembolic stroke (CE) caused by paroxysmal atrial fibrillation (Paf) sometimes show normal sinus rhythm on admission, which makes it difficult to diagnose them as having CE. The present study examined the differences in echocardiographic findings between patients with CE caused by Paf (the Paf-CE grou... |
5,353 | Synthetic ECG generation and Bayesian filtering using a Gaussian wave-based dynamical model. | In this paper, we describe a Gaussian wave-based state space to model the temporal dynamics of electrocardiogram (ECG) signals. It is shown that this model may be effectively used for generating synthetic ECGs as well as separate characteristic waves (CWs) such as the atrial and ventricular complexes. The model uses se... |
5,354 | Absence of calcium channel alpha1C-subunit mutation in human atrial fibrillation. | L-type voltage-gated calcium channel mutation or phenotypical variation resulting from alternative splicing has been associated with sudden arrhythmogenic death and heart failure. Changes in calcium current density, protein and mRNA expression have been associated with atrial fibrillation. We studied human atrium harve... |
5,355 | Gender-specific differences in the clinical features of hypertrophic cardiomyopathy in a community-based Japanese population: results from Kochi RYOMA study. | Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with a broad spectrum of clinical features. Although gender may be one of the important modifying factors in HCM, there has been little information on gender differences.</AbstractText>We investigated gender-specific differences in the clinical features... |
5,356 | Improving contemporary algorithms for implantable cardioverter-defibrillator function. | Implantable cardioverter-defibrillators (ICDs) have been shown in various clinical trials to prevent mortality from sudden cardiac death due to unstable rhythms or ventricular fibrillation. Modern ICDs use sophisticated algorithms to not only deliver therapy on the detection of a malignant rhythm but also reduce the in... |
5,357 | Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias. | Myocardial ischaemia is associated with perturbations of electrophysiological profile of cardiac myocytes. The persistent sodium current (I(Nap)) is one of the major contributors to ischaemic arrhythmias and appears as an attractive therapeutic target. We investigated the effects of F 15845, a new anti-anginal drug on ... |
5,358 | Reduction of reperfusion-induced ventricular fibrillation and infarct size via heme oxygenase-1 overexpression in isolated mouse hearts. | Heme oxygenase-1 (HO-1), also known as heat shock protein 32 (hsp-32) is a stress induced cytoprotective protein. The present investigation evaluated the capacity of HO-1 to reduce the incidence of reperfusion-induced ventricular fibrillation (VF) and infarct size. HO-1 transgenic (Tg) mice were generated using a rat H... |
5,359 | [News in hemodynamic monitoring, resuscitation and intensive care of patients after cardiac surgery: "Guidelines for resuscitation in cardiac arrest after cardiac surgery" of the European Association for Cardio-Thoracic Surgery]. | In order to simplify and to standardize procedures during cardiac arrest in patients after cardiac surgery and for professional medical staff education, working group of the European Association for Cardio-Thoracic Surgery issued in 2009 "Guideline for resuscitation in cardiac arest after cardiac surgery". There are se... |
5,360 | Arrhythmia burden in adults with surgically repaired tetralogy of Fallot: a multi-institutional study. | The arrhythmia burden in tetralogy of Fallot, types of arrhythmias encountered, and risk profile may change as the population ages.</AbstractText>The Alliance for Adult Research in Congenital Cardiology (AARCC) conducted a multicenter cross-sectional study to quantify the arrhythmia burden in tetralogy of Fallot, to ch... |
5,361 | Impact of myocardial perfusion abnormality on prognosis in patients with non-ischemic dilated cardiomyopathy. | Myocardial perfusion imaging shows various patterns in patients with non-ischemic dilated cardiomyopathy (DCM). However, influences of regional abnormalities of myocardial perfusion or ventricular wall motion on prognosis in DCM patients remains to be clarified. Accordingly, we investigated a relation between myocardia... |
5,362 | Circadian, weekly, and seasonal mortality variations in out-of-hospital cardiac arrest in Japan: analysis from AMI-Kyoto Multicenter Risk Study database. | Several studies have reported circadian, weekly, and seasonal variations in the rates of out-of-hospital cardiac arrest (OHCA). However, variations in the mortality of OHCA are not well known.</AbstractText>We investigated the 1396 consecutive cases of OHCA with cardiac etiology between October 2004 and September 2008.... |
5,363 | Analysis of transthoracic impedance during real cardiac arrest defibrillation attempts in older children and adolescents: are stacked-shocks appropriate? | In 2005, the AHA changed the treatment recommendation for shockable rhythms from 3 transthoracic stacked-shocks to a single shock followed by immediate chest compressions. The stacked-shock recommendation was based on low first-shock efficacy of monophasic waveforms and the theoretical decrease in transthoracic impedan... |
5,364 | Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest. | Therapeutic hypothermia has been shown to provide neuroprotection and improved survival in patients suffering a cardiac arrest. We report outcomes of consecutive patients receiving therapeutic hypothermia for cardiac arrest and describe predictors of short and long-term survival.</AbstractText>Eighty patients receiving... |
5,365 | Pre- and post-operative cardiac evaluation of dogs undergoing lobectomy and pneumonectomy. | This study aimed to assess the influence of lobectomy and pneumonectomy on cardiac rhythm and on the dimensions and function of the right-side of the heart. Twelve dogs undergoing lobectomy and eight dogs undergoing pneumonectomy were evaluated preoperatively and one month postoperatively with electrocardiography and D... |
5,366 | The Intermountain Risk Score (including the red cell distribution width) predicts heart failure and other morbidity endpoints. | The complete blood count (CBC) and basic metabolic profile are common, low-cost blood tests, which have previously been used to create and validate the Intermountain Risk Score (IMRS) for mortality prediction. Mortality is the most definitive clinical endpoint, but medical care is more easily applied to modify morbidit... |
5,367 | Sudden cardiac death secondary to demonstrated reperfusion ventricular fibrillation in a woman with Takotsubo cardiomyopathy. | Takotsubo cardiomyopathy is a left ventricle cardiomyopathy characterized by a reversible dyskinesia responsible for the typical apical ballooning aspect. The disease is considered benignant with a full recovery within a few weeks. We present the case of a 52-year-old woman who presented with angina diagnosed with Tako... |
5,368 | [Modern technology in cardiovascular medicine]. | Despite basic physiologic principles being well known for more than 300 years, the diagnosis and therapy of cardiovascular diseases are still in their early beginnings. For example, 100 years ago sudden cardiac arrest was regarded as the result of toxic gases. The diagnosis of ventricular fibrillation or treatment with... |
5,369 | Body mass index and survival after in-hospital cardiac arrest. | The quality and effectiveness of resuscitation processes may be influenced by the patient's body mass index (BMI); however, the relationship between BMI and survival after in-hospital cardiac arrest has not been previously studied.</AbstractText>We evaluated 21 237 adult patients with an in-hospital cardiac arrest with... |
5,370 | Are new resuscitation guidelines better? Experience of an Asian metropolitan hospital. | Cardiopulmonary resuscitation (CPR) guidelines were revised in 2005 based on new evidence and expert consensus. However, the benefits of the new guidelines remain undetermined and their influence has not been published in Asia. This study aimed to evaluate the impact of implementing the new resuscitation guidelines and... |
5,371 | An eight year review of exercise-related cardiac arrests. | Exercise-related cardiac arrest is uncommon, however it is devastating when it occurs in otherwise healthy adults. This study aims to identify the characteristics of exercise-related cardiac arrest in the study population and estimate the overall survival rate.</AbstractText>This is a retrospective observational study ... |
5,372 | Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells. | Renin released by ischemia/reperfusion from cardiac mast cells activates a local renin-angiotensin system (RAS). This exacerbates norepinephrine release and reperfusion arrhythmias (ventricular tachycardia and fibrillation), making RAS a new therapeutic target in myocardial ischemia.</AbstractText>We investigated wheth... |
5,373 | Gene therapy strategies for cardiac electrical dysfunction. | Cardiac disease is frequently associated with abnormalities in electrical function that can severely impair cardiac performance with potentially fatal consequences. The available therapeutic options have some efficacy but are far from perfect. The curative potential of gene therapy makes it an attractive approach for t... |
5,374 | The effects of epinephrine on outcomes of normothermic and therapeutic hypothermic cardiopulmonary resuscitation. | To investigate the effects of epinephrine when administered during either normothermic or therapeutic hypothermic cardiopulmonary resuscitation on postresuscitation myocardial and cerebral function and survival.</AbstractText>Prospective, randomized, placebo-controlled experimental study.</AbstractText>University-affil... |
5,375 | Morbidity and mortality in heart failure patients treated with cardiac resynchronization therapy: influence of pre-implantation characteristics on long-term outcome. | Cardiac resynchronization therapy (CRT) improves cardiac function, heart failure symptoms, and prognosis in selected patients. Many baseline characteristics associated with heart failure may influence prognosis after CRT. The objective of this study was to evaluate the effect of several baseline characteristics in rela... |
5,376 | Plasma renin activity and pro-B-type natriuretic peptide levels in different atrial fibrillation types. | Renin-angiotensin system may be activated during atrial fibrillation (AF). Our aim was to evaluate plasma renin activity (PRA) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in patients with different AF types who had normal left ventricular (LV) systolic function.</AbstractText>This cross-sectional s... |
5,377 | Efficacy of levosimendan in patients with chronic heart failure: Does rhythm matter? | Levosimendan is a relatively new inotropic agent. Unlike other inotropic agents, Levosimendan does not increase cellular calcium intake, so that, does not cause intracellular calcium overload and related arrhythmias. Atrial fibrillation (AF) was shown to be an independent risk factor for mortality and morbidity in larg... |
5,378 | [Quality of records in OMI-AP of the patients with stroke followed in primary care]. | 1) To determine the level of registration and control of cardiovascular risk factors in stroke patients treated in primary care in Murcia through electronic medical records. 2) To describe the registered drug treatment in patients with stroke.</AbstractText>Observational descriptive, retrospective, evaluated through th... |
5,379 | Predictive value of preoperative tissue Doppler echocardiographic analysis for postoperative atrial fibrillation after pulmonary resection for lung cancer. | The objective of the present study was to evaluate the utility of tissue Doppler imaging for predicting the development of postoperative atrial fibrillation.</AbstractText>In this prospective observational study, we evaluated 126 patients with lung cancer who underwent a lobectomy during the 18-month period from August... |
5,380 | Early repolarization, left ventricular diastolic function, and left atrial size in professional soccer players. | Recent data have suggested a relation among long-term endurance sport practice, left atrial remodeling, and atrial fibrillation. We investigated the influence of an increased vagal tone, represented by the early repolarization (ER) pattern, on diastolic function and left atrial size in professional soccer players. Fift... |
5,381 | Continued breathing followed by gasping or apnea in a swine model of ventricular fibrillation cardiac arrest. | Continued breathing following ventricular fibrillation has here-to-fore not been described.</AbstractText>We analyzed the spontaneous ventilatory activity during the first several minutes of ventricular fibrillation (VF) in our isoflurane anesthesized swine model of out-of-hospital cardiac arrest. The frequency and typ... |
5,382 | An observational study to assess changes in arterial blood gas values during untreated porcine ventricular fibrillation. | Cardiocerebral resuscitation (CCR) is reportedly superior to cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) even though active ventilation is not initially provided. Understandably, concerns have been raised regarding the withholding of positive pressure ventilation (PPV) during CCR becau... |
5,383 | Anti-tachycardia pacing degenerated fast ventricular tachycardia into undetectable life-threatening tachyarrhythmia in a patient with non-ischemic dilated cardiomyopathy. | A 45-year-old man with dilated cardiomyopathy was admitted to our hospital due to congestive heart failure (CHF). Despite the optimal medical treatment, his condition had not improved because of severe left ventricular dysfunction. Because he experienced non-sustained ventricular tachycardia (VT), a biventricular impla... |
5,384 | The effect of early and intensive statin therapy on ventricular premature beat or non-sustained ventricular tachycardia in patients with acute coronary syndrome. | Our study's aim was to evaluate the prognostic value of early and intensive lipid-lowering treatment on ventricular premature beat or non-sustained ventricular tachycardia (NSVT) after acute coronary syndrome (STEMI, non-STEMI, and unstable angina pectoris).</AbstractText>Some 586 patients with acute coronary syndrome ... |
5,385 | Cardiac arrhythmia and thyroid dysfunction: a novel genetic link. | Inherited Long QT Syndrome (LQTS), a cardiac arrhythmia that predisposes to the often lethal ventricular fibrillation, is commonly linked to mutations in KCNQ1. The KCNQ1 voltage-gated K(+) channel α subunit passes ventricular myocyte K(+) current that helps bring a timely end to each heart-beat. KCNQ1, like many... |
5,386 | Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy. | We investigated the significance of fibrosis detected by late gadolinium enhancement cardiovascular magnetic resonance for the prediction of major clinical events in hypertrophic cardiomyopathy (HCM).</AbstractText>The role of myocardial fibrosis in the prediction of sudden death and heart failure in HCM is unclear wit... |
5,387 | A case of fulminant myocarditis associated with novel N1H1 influenza successfully treated by percutaneous cardiopulmonary support system. | We report a case of fulminant myocarditis associated with N1H1 influenza virus infection. N1H1 was confirmed by a polymerase chain reaction assay and she was treated with oseltamivir phosphate. She was admitted to the hospital because of respiratory distress, however, echocardiography revealed severely depressed wall m... |
5,388 | Atrial pacing or ventricular backup-only pacing in implantable cardioverter-defibrillator patients. | The need for pacing support in typical ICD patients is unknown.</AbstractText>This study sought to determine whether atrial pacing with ventricular backup pacing is equivalent to ventricular backup pacing only in implantable cardioverter-defibrillator (ICD) patients.</AbstractText>We randomized 1,030 patients from 84 s... |
5,389 | Effect of continuous compressions and 30:2 cardiopulmonary resuscitation on global ventilation/perfusion values during resuscitation in a porcine model. | Rescue ventilations during bystander resuscitation, although previously considered essential, interrupt the continuity of chest compressions and might have deleterious effects in basic life support. This study was undertaken to analyze the global ventilation/perfusion values of continuous compressions and 30:2 cardiopu... |
5,390 | Impact of angiotensin-converting enzyme-inhibitors and angiotensin receptor blockers on long-term outcome of catheter ablation for atrial fibrillation. | We hypothesized that modulation of the renin-angiotensin-aldosterone system (RAAS) improves success following catheter ablation for atrial fibrillation (AF).</AbstractText>We examined a prospective registry of consecutive patients undergoing catheter ablation of paroxysmal or persistent AF between November 2004 and Dec... |
5,391 | Premature coronary artery disease in a patient with glycogen storage disease III. | The glycogen storage diseases are a rare form of inherited metabolic disease affecting intracellular glycogen metabolism, and several studies suggest glycogen storage disease (GSD) III predisposes patients to dyslipidemia and endothelial dysfunction. The presence of premature atherosclerotic heart disease in patients w... |
5,392 | Induction of therapeutic hypothermia by paramedics after resuscitation from out-of-hospital ventricular fibrillation cardiac arrest: a randomized controlled trial. | Therapeutic hypothermia is recommended for the treatment of neurological injury after resuscitation from out-of-hospital cardiac arrest. Laboratory studies have suggested that earlier cooling may be associated with improved neurological outcomes. We hypothesized that induction of therapeutic hypothermia by paramedics b... |
5,393 | Metformin is associated with improved left ventricular diastolic function measured by tissue Doppler imaging in patients with diabetes. | To examine the association between selected glucose-lowering medications and left ventricular (LV) diastolic function in patients with diabetes.</AbstractText>Retrospective cohort study (years 2005-2008).</AbstractText>Echocardiograms of 242 patients with diabetes undergoing coronary angiography were analyzed. All pati... |
5,394 | [Mortality prognosis factors in heart failure in a cohort of North-West Spain. EPICOUR study]. | Heart failure (HF) is a serious health problem in Spain because it has a high mortality rate and causes considerable costs to the health-care system. This paper presents a study made in the Spanish province of Ourense to study the survival of patients with HF related to the ventricular function or other possible risk f... |
5,395 | Cardiac arrest with "pseudo-Brugada" ECG pattern in the setting of a coronary artery anomaly. | A 36-year-old Hispanic man with no prior cardiac history presented with chest pain and then ventricular fibrillation requiring defibrillation after a physical altercation. His ECG on presentation to the emergency room was suggestive of Brugada syndrome, which later normalized. Cardiac catheterization revealed anomalous... |
5,396 | Clinical effectiveness of pulmonary vein isolation for arrhythmic events in a patient with catecholaminergic polymorphic ventricular tachycardia. | An 18-year-old woman with catecholaminergic polymorphic ventricular tachycardia (CPVT) underwent pulmonary vein isolation (PVI) because of frequent and inappropriate shocks from an implantable cardioverter defibrillator (ICD) associated with atrial fibrillation (AF) with a rapid ventricular response. While the PVI did ... |
5,397 | [Psychosomatic aspects of cardiac arrhythmias]. | Emotional stress facilitates the occurrence of cardiac arrhythmias including sudden cardiac death. The prevalence of anxiety and depression is increased in cardiac patients as compared to the normal population. The risk of cardiovascular mortality is enhanced in patients suffering from depression. Comorbid anxiety diso... |
5,398 | [In-hospital resuscitation concept with first-responder defibrillation. 2-year experience]. | Sudden cardiac arrest appears in 1-5 patients/ 1,000 clinical admissions. In spite of different research approaches, the prognosis after in-hospital resuscitation has not significantly improved in the last 40 years. This account presents the experiences with a hospital-wide emergency plan using the concept of defibrill... |
5,399 | Acute amiodarone promotes drift and early termination of spiral wave re-entry. | Intravenous application of amiodarone is commonly used in the treatment of life-threatening arrhythmias, but the underlying mechanism is not fully understood. The purpose of the present study is to investigate the acute effects of amiodarone on spiral wave (SW) re-entry, the primary organization machinery of ventricula... |
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