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6,400 | Catheter ablation versus standard conventional treatment in patients with left ventricular dysfunction and atrial fibrillation (CASTLE-AF) - study design. | Electrical isolation of the pulmonary veins by catheter ablation is an emerging treatment modality for the treatment of atrial fibrillation (AF) and is increasingly used in patients with heart failure.</AbstractText>The catheter ablation versus standard conventional treatment in patients with left ventricular dysfuncti... |
6,401 | Catheter ablation of recurrent scar-related ventricular tachycardia using electroanatomical mapping and irrigated ablation technology: results of the prospective multicenter Euro-VT-study. | Ventricular tachycardia (VT) late after myocardial infarction is an important contributor to morbidity and mortality. This prospective multicenter study assessed the efficacy and safety of electroanatomical mapping in combination with open-saline irrigated ablation technology for ablation of chronic recurrent mappable ... |
6,402 | [Right ventricular cardiac failure in hospitalized patients with chronic obstructive pulmonary disease: prevalence and clinical and instrumental characteristics]. | The prevalence of right ventricular cardiac failure (CF) and its characteristics were analysed in 326 hospitalized elderly patients with chronic obstructive pulmonary disease (COPD) (average age 70+/-11 years). At admission right ventricular CF was diagnosed in 107 (33%) patients with COPD; its prevalence did not depen... |
6,403 | [Treatment of patients with long nocturnal asystoles and obstructive sleep apnea syndrome by creating continuous positive air pressure in the upper respiratory tract]. | To study prevalence of obstructive sleep apnea syndrome (OSAS) in patients with nocturnal asystoles, and assess therapeutic efficiency of constant positive air pressure (CPAP) applied to upper respiratory tract in this category of patients.</AbstractText>The study incorporated 37 patients (33 men and 4 women, average a... |
6,404 | [Repetitive hospitalizations of patients with chronic heart failure according to data of one year follow-up study]. | Patients with chronic heart failure (CHF) represent a group with high risk of repetitive hospitalizations. In order to assess frequency of repetitive hospitalizations and elucidate their risk factors we included in this study 962 patients with stage IIA-III and functional class II-IV CHF hospitalized in a multiprofile ... |
6,405 | Neurotoxic and cardiotoxic effects of cocaine and ethanol. | Concurrent abuse of alcohol and cocaine results in the formation of cocaethylene, a powerful cocaine metabolite. Cocaethylene potentiates the direct cardiotoxic and indirect neurotoxic effects of cocaine or alcohol alone.</AbstractText>A 44-year-old female with history of cocaine and alcohol abuse presented with massiv... |
6,406 | Burst stimulation improves hemodynamics during resuscitation after prolonged ventricular fibrillation. | Although return of spontaneous circulation (ROSC) is frequently achieved during resuscitation for sudden cardiac arrest, systolic blood pressure can then decrease, requiring additional myocardial support. Previous studies have shown that a series of 1-ms electrical pulses delivered through the defibrillation patches du... |
6,407 | Stress cardiomyopathy and arrhythmic storm in a 14-year-old boy. | Stress cardiomyopathy is a newly described reversible cardiomyopathy, characterized by transient cardiac dysfunction usually precipitated by intense emotional or physical stress. Apart from the classical apical ballooning syndrome (Takotsubo), it is now increasingly recognized that the spectrum of stress cardiomyopathi... |
6,408 | Undersensing of ventricular fibrillation due to interference between a pacemaker and defibrillator in the same patient. | Sensing in pacemakers (PMs) and implantable cardioverter defibrillators (ICDs) is crucial to normal device behaviour. Since both devices treat different arrhythmias, the technical approach to signal detection is also completely different. A PM has a fixed threshold of sensing, above which events are sensed and therapy ... |
6,409 | What have we learned about the contribution of autonomic nervous system to human arrhythmia? | Myocardial infarction results in denervation, followed by neural remodeling characterized by nerve sprouting and heterogeneous sympathetic hyperinnervation throughout the myocardium. There is an association between the density of sympathetic nerves and occurrence of cardiac arrhythmia in humans. Autonomic nerve recordi... |
6,410 | Mechanisms and clinical management of inherited channelopathies: long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and short QT syndrome. | The following briefly reviews features and management of long QT syndrome (LQTS), Brugada Syndrome, catecholaminergic polymorphic ventricular tachycardia (CPVT), and short QT syndrome (SQTS). LQTS is marked by QT prolongation, syncope and sudden death due to torsades de pointes. Risk stratification is based on age, gen... |
6,411 | Predictors of ventricular tachycardia induction in syncopal patients with mild to moderate left ventricular dysfunction. | In patients with mild to moderate left ventricular dysfunction (LVD) (35% pound LVEF pound 50%) who present with syncope, demonstration of tachy and/or brady-arrhythmia has prognostic value. In this group of patients electrophysiological study (EPS) is often necessary.</AbstractText>A total of 53 consecutive patients w... |
6,412 | Repetitive endocardial focal discharges during ventricular fibrillation with prolonged global ischemia in isolated rabbit hearts. | Ventricular fibrillation (VF) during prolonged (>5 min) global ischemia (GI) could be due to repetitive endocardial focal discharges (REFDs). This hypothesis was tested in isolated rabbit hearts.</AbstractText>With optical mapping, simultaneous endocardial (left ventricle, LV) and epicardial (both ventricles) activa... |
6,413 | Ventricular fibrillation diagnosed with trans-thoracic echocardiography. | Electrocardiographic artifacts on scope are frequently observed in pre-hospital settings. They can lead to misdiagnosis or inappropriate resuscitation treatments. Here we report a case of ventricular fibrillation by electrical injury masked by ECG artifacts, after the savage of a victim, due to persistent 50Hz domestic... |
6,414 | [Malignant form of familial hypertrophic cardiomyopathy complicated with ventricular fibrillation in siblings. Electrocardiogram in hypertrophic cardiomyopathy - a review]. | A family with hypertrophic cardiomyopathy (HCM) (15-year-old boy, his 17-year-old sister and 45-year-old father) is described. The first sign of HCM was cardiac arrest (CA) due to ventricular fibrillation (VF) in a boy. A few months later sister of proband had the episode of CA due to VF. Both had implanted cardioverte... |
6,415 | Atrial fibrillation is under-recognized in chronic heart failure: insights from a heart failure cohort treated with cardiac resynchronization therapy. | Atrial fibrillation (AF) is the most common sustained arrhythmia in patients with chronic heart failure (CHF). Under-detection of asymptomatic paroxysmal AF (PAF) underestimates the true burden of AF in patients with CHF. We retrospectively studied the prevalence of asymptomatic PAF in 162 CHF patients through analysis... |
6,416 | ACE I/D polymorphism associated with abnormal atrial and atrioventricular conduction in lone atrial fibrillation and structural heart disease: implications for electrical remodeling. | The angiotensin-converting enzyme (ACE) gene contains a common polymorphism based on the insertion (I) or deletion (D) of a 287-bp intronic DNA fragment. The D allele is associated with higher ACE activity and thus higher angiotensin II levels. Angiotensin II stimulates cardiac fibrosis and conduction heterogeneity.</A... |
6,417 | Cardiac signal extraction in patients with Implantable Cardioverter Defibrillators. | According to the guidelines the indication for Implantable Cardioverter Defibrillator (ICD) implantation is based on the ejection fraction. However, only a fraction of patients with implanted ICD shows live threatening arrhythmic events followed by adequate shocks. For this reason, further research is needed to find a ... |
6,418 | Use of real time three-dimensional transesophageal echocardiography in intracardiac catheter based interventions. | Real-time three-dimensional (RT3D) echocardiography is a recently developed technique that is being increasingly used in echocardiography laboratories. Over the past several years, improvements in transducer technologies have allowed development of a full matrix-array transducer that allows acquisition of pyramidal-sha... |
6,419 | P wave and QT changes among inpatients with schizophrenia after parenteral ziprasidone administration. | Although ziprasidone has been reported to cause ventricular arrhythmias, there have been no studies regarding the influence of ziprasidone on atrial conduction. Intraatrial and interatrial conduction time prolongation and inhomogeneous propagation of sinus impulses are indicated by P wave changes on surface electrocard... |
6,420 | Combination therapy with digoxin and diltiazem controls ventricular rate in chronic atrial fibrillation in dogs better than digoxin or diltiazem monotherapy: a randomized crossover study in 18 dogs. | Atrial fibrillation (AF) with excessively high ventricular rates (VR) occurs in dogs with advanced heart disease. Rate control improves clinical signs in these patients. Optimal drug therapy and target VR remain poorly defined.</AbstractText>Digoxin-diltiazem combination therapy reduces VR more than either drug alone i... |
6,421 | Epicardially Based Pulmonary Vein Isolation for the Treatment of Atrial Fibrillation Utilizing Laser Energy in the Pig Model. | <b>Purpose:</b> Atrial fibrillation is a common disease that increases the incidence of cerebrovascular embolic events and cardiac dysfunction. Foci for atrial fibrillation have been mapped and found to be for the most part located within the ostia of the pulmonary veins. Since 2002 microwave and radiofrequency energy ... |
6,422 | The Autonomic Nervous System and Atrial Fibrillation:The Roles of Pulmonary Vein Isolation and Ganglionated Plexi Ablation. | After the sequential successes of catheter ablation for the treatment of pre-excitation syndromes (WPW), junctional reentry (AVNRT) atrial flutter (AFL) and ventricular arrhythmias, clinical electrophysiologists have focused on the myocardial basis of atrial fibrillation (AF). Thus, the strategy for ablation of drug an... |
6,423 | Use of automated external defibrillator in Peruvian out-of-hospital environment: improving emergency response in Latin America. | This case report relates out-of-hospital care to a patient with risk factors treated in the out-of-hospital services after cardiac arrest and ventricular fibrillation. The patient was treated according to the standards of basic life support and advanced cardiovascular life support; by applying an automated external def... |
6,424 | [Role of hyperviscosity in cardiovascular and microvascular diseases]. | Blood viscosity plays a key role in regulating microvascular flow and alterations of hemorheological variables can lead to hyperviscosity, thus favoring the occurrence of occlusive thrombotic events. In the last few years an association between alterations in the hemorheologic profile and the severity of blood flow dis... |
6,425 | Predictors of adverse neurological outcome following cardiac surgery. | Stroke is a debilitating complication of cardiac surgery. Many intraoperative and postoperative factors predict the likelihood of post-cardiac surgery stroke. We evaluated preoperative parameters, seeking correlations with adverse neurological outcome following cardiac surgery. We investigated the possibility of preope... |
6,426 | Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). | Heart failure (HF) with preserved ejection fraction (EF) is common. We compared the characteristics, treatments, and outcomes in HF patients with reduced vs preserved EF by using the national registry database in Japan.</AbstractText>The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) is a prospec... |
6,427 | Left ventricle radio-frequency ablation in the rat: a new model of heart failure due to myocardial infarction homogeneous in size and low in mortality. | The purpose of the current study was to create a model of myocardial infarction (MI) that is homogeneous in size with a low immediate (24 hours) mortality.</AbstractText>Male and female rats (n = 256) underwent left ventricle (LV) ablation (Ab) by a radiofrequency current (1000 kHz; 12 watts for 12 seconds) to promote ... |
6,428 | Magnetic resonance imaging at 1.5-T in patients with implantable cardioverter-defibrillators. | Our aim was to establish and evaluate a strategy for safe performance of magnetic resonance imaging (MRI) at 1.5-T in patients with implantable cardioverter-defibrillators (ICDs).</AbstractText>Expanding indications for ICD placement and MRI becoming the imaging modality of choice for many indications has created a gro... |
6,429 | Long-term follow-up of idiopathic ventricular fibrillation ablation: a multicenter study. | This multicenter study sought to evaluate the long-term follow-up of patients ablated for idiopathic ventricular fibrillation (VF).</AbstractText>Catheter ablation of idiopathic VF that targets ventricular premature beat (VPB) triggers has been shown to prevent VF recurrences on short-term follow-up.</AbstractText>From... |
6,430 | Cardiac function and the proinflammatory cytokine response after recovery from cardiac arrest in swine. | Increased levels of cytokines have been reported after resuscitation from cardiac arrest. We hypothesized that proinflammatory cytokines, released in response to ischemia/reperfusion, increase following resuscitation and play a role in post-cardiac arrest myocardial dysfunction. Ventricular fibrillation (VF) was induce... |
6,431 | Review and management of the dental patient with Long QT syndrome (LQTS). | Long QT syndrome (LQTS) is a unique cardiovascular condition, with both congenital and acquired forms that afflict patients. These patients show a lengthening of the repolarization phase of the cardiac cycle, which can be best visualized on an electrocardiogram (ECG). The ECG changes can include QT interval (the time b... |
6,432 | Electrophysiological characteristics associated with symptoms in pacemaker patients with paroxysmal atrial fibrillation. | The purpose of this study is to identify the electrophysiological factors affecting symptoms in paroxysmal atrial fibrillation (PAF) using patients with paroxysmal atrial fibrillation and pacemakers with advanced atrial fibrillation (AF) diagnostics.</AbstractText>Seventy-nine patients (age 71.0 +/- 8.2, 54.4% male) wi... |
6,433 | HIV protease inhibitors induced prolongation of the QT Interval: electrophysiology and clinical implications. | In recent years, there have been considerable advancements in our understanding of the role of ionic channels in mediating cardiac repolarization. Advances in ion channel cloning have generated great interest in the diagnosis and understanding of electrophysiological processes involved in ventricular repolarization, pa... |
6,434 | [Chaos and fractals and their applications in electrocardial signal research]. | Chaos and fractals are ubiquitous phenomena of nature. A system with fractal structure usually behaves chaos. As a complicated nonlinear dynamics system, heart has fractals structure and behaves as chaos. The deeper inherent mechanism of heart can be opened out when the chaos and fractals theory is utilized in the rese... |
6,435 | Long-term clinical outcome of mitral valve repair in asymptomatic severe mitral regurgitation. | To assess the long-term survival, the incidence of cardiac complications and the factors that predict outcome in asymptomatic patients with severe degenerative mitral regurgitation (MR) undergoing mitral valve repair.</AbstractText>Up to 143 asymptomatic patients (mean age 63+/-12 years) with severe degenerative MR who... |
6,436 | Comparison of pulmonary veins anatomy in patients with and without atrial fibrillation: analysis by multislice tomography. | A possible role of anomalies in number and insertion of pulmonary veins (PV) in initiating atrial fibrillation (AF) has been suggested. It has been shown as well that changes in anatomy of PVs such as enlargement may have an effect on arrhythmogenesis. The aim of the study was to compare anatomy of the left atrium (LA)... |
6,437 | Abnormal transmural repolarization process in patients with Brugada syndrome. | Repolarization abnormality, especially during bradycardia, might be critical for initiation of ventricular fibrillation (VF) in patients with Brugada syndrome (BrS), but the contribution of the rate-dependent repolarization dynamics to the occurrence of VF is still unknown.</AbstractText>The aim of our study was to det... |
6,438 | Long-term outcomes and clinical predictors for pacing after cardiac transplantation. | Prior studies have yielded inconsistent results on bradyarrhythmias requiring a permanent pacemaker (PPM) after cardiac transplant. This study evaluated the predictors for PPM requirement, long-term outcomes, and influence of implant timing and device programming on prognosis after cardiac transplant.</AbstractText>Thi... |
6,439 | Serial evaluation of electrocardiographic left ventricular hypertrophy for prediction of risk in hypertensive patients. | Although the presence and severity of electrocardiographic (ECG) left ventricular hypertrophy (LVH) have been associated with an increased risk of cardiovascular (CV) morbidity and mortality, the relationship of regression of ECG LVH during antihypertensive therapy to CV risk has only recently been examined.</AbstractT... |
6,440 | Percutaneous left ventricular assist device can prevent acute cerebral ischaemia during ventricular fibrillation. | A percutaneous left ventricular assist device has been shown to be able to perfuse cardiac and cerebral tissues during cardiac arrest and may be a useful supplement to current methods in resuscitation. We wished to assess device-assisted circulation during cardiac arrest with microspheres injections and continuous end-... |
6,441 | Changes in the frequency spectrum, the P-P interval, and the bispectral index during ventricular fibrillation are physiologic indicators of ventricular fibrillation duration. | The 3-phase time-sensitive model by Weisfeldt and Becker in 2002 has resulted in a redirection of efforts toward developing treatment algorithms specific to each phase of cardiac arrest. In this study, a number of physiologic indicators of ventricular fibrillation (VF) duration were investigated. The bispectral index w... |
6,442 | Cardiac magnetic resonance imaging assessment of regional and global left atrial function before and after catheter ablation for atrial fibrillation. | Ablation of the left atrium and pulmonary veins antrum (PVAI) can be an effective treatment of atrial fibrillation (AF). However, there is discrepancy in the literature regarding the effect extensive ablation has on left atrial (LA) function. We sought to evaluate the effect that AF ablation procedures has on global an... |
6,443 | Fluctuation in ventricular sensing leading to underdetection of ventricular fibrillation in a patient with cardiac sarcoidosis. | In this case report, we describe markedly fluctuating ventricular sensing through an implantable cardioverter defibrillator (ICD) over a period of 29 months in a patient with cardiac sarcoidosis. We conclude that the fluctuations in the measured R wave are the result of waxing and waning inflammation associated with sa... |
6,444 | Validating optimal function of the closed loop stimulation sensor with high right septal ventricular electrode placement in 'ablate and pace' patients. | The study aim was to validate the closed loop stimulation (CLS) vs. accelerometer (ACC) rate-responsive sensors with electrodes placed in the right ventricular high septal (RVHS) or right ventricular apical (RVA) lead positions in patients following 'ablate and pace' therapy for persistent atrial fibrillation.</Abstrac... |
6,445 | Comparison of acute electrocardiographic presentation in patients with diastolic vs systolic heart failure. | There are limited data comparing admission electrocardiograms (ECGs) in patients with acute diastolic (DHF) vs systolic heart failure (SHF) and their ability to predict cardiac events (CEs). Admission ECGs were evaluated in 241 acute heart failure patients (88 DHF; 153 SHF). DHF was defined as left ventricular ejection... |
6,446 | Simvastatin alleviates myocardial contractile dysfunction and lethal ischemic injury in rat heart independent of cholesterol-lowering effects. | Statins, the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, are most frequently used drugs in the prevention of coronary artery disease due to their cholesterol-lowering activity. However, it is not exactly known whether these effects of statins or those independent of cholesterol decrease acc... |
6,447 | Ablate and pace as bail-out therapy in a patient with Fontan correction and malignant atrial tachycardia. | Atrial tachyarhthmias complicating Fontan correction may have a 'malignant' clinical presentation seriously impairing the patient haemodynamic. Current strategies are surgical total cavopulmonary connection with or without antiarrhythmic surgery or transcatheter ablation. We describe the case of a patient who previousl... |
6,448 | Arrhythmogenic right ventricular cardiomyopathy presenting with intra-operative aborted sudden cardiac death and TakotsuboLike left ventricular functional abnormalities. | A 46-year-old female under treatment with flecainide for atrial fibrillation developed cardiopulmonary arrest secondary to ventricular fibrillation during an elective laparoscopic cholecystectomy. The ECG after cardioversion demonstrated a prolonged QTc interval with elevated cardiac enzymes. A diagnosis of Takotsubo c... |
6,449 | Nicosia General Hospital cardiac arrest team: first year's practice and outcomes of in-hospital resuscitation. | In 2007, Nicosia General Hospital implemented a resuscitation policy. 378 nurses and 120 doctors were successfully trained in advanced life support (ALS) in order to staff cardiac arrest teams. The aim of this study was to assess the frequency of cardiac arrest and resuscitation outcomes in Nicosia General Hospital and... |
6,450 | Mitral valve replacement with the pulmonary autograft: midterm results. | We performed mitral valve replacement with a pulmonary autograft using the technique described by us earlier and present the results.</AbstractText>Between August 2000 and July 2007, 19 patients (16 male patients; age, 30-58 years) with isolated calcific mitral stenosis (n = 16) or mixed mitral stenosis and regurgitati... |
6,451 | Use of preoperative natriuretic peptides and echocardiographic parameters in predicting new-onset atrial fibrillation after coronary artery bypass grafting: a prospective comparative study. | Atrial fibrillation (AF) is a common complication after coronary artery bypass grafting (CABG). We prospectively compared the ability of echocardiographic parameters and the cardiac neurohormones, brain natriuretic peptide (BNP), and N-terminal pro-brain natriuretic peptide (NT-proBNP) to predict AF in this setting.</A... |
6,452 | The association between early ventricular arrhythmias, renin-angiotensin-aldosterone system antagonism, and mortality in patients with ST-segment-elevation myocardial infarction: Insights from Global Use of Strategies to Open coronary arteries (GUSTO) V. | The long-term prognostic significance of early (<48 hours) ventricular fibrillation (VF) or sustained ventricular tachycardia (VT) in patients with an acute myocardial infarction remains controversial. Emerging data suggest that some of the benefit of renin-angiotensin-aldosterone system (RAAS) antagonism may be der... |
6,453 | Rates and predictors of appropriate implantable cardioverter-defibrillator therapy delivery: results from the EVADEF cohort study. | The implantable cardioverter defibrillator (ICD) is the therapy of choice in patients at risk for sudden cardiac death in both primary and secondary prevention indication. There are no recent data concerning the delivery rate and etiology of appropriate ICD therapies in routine medical care.</AbstractText>The EVADEF st... |
6,454 | Statins reduce appropriate cardioverter-defibrillator shocks and mortality in patients with heart failure and combined cardiac resynchronization and implantable cardioverter-defibrillator therapy. | Of 209 patients with heart failure treated with combined cardiac resynchronization therapy and implantable cardioverter-defibrillator therapy, appropriate cardioverter-defibrillator shocks occurred at 34-month follow-up in 22 of 121 patients (18%) on statins and in 30 of 88 patients (34%) not on statins (P = .009). Dea... |
6,455 | Atrial fibrillation in primary aldosteronism. | Primary aldosteronism (PA) is caused by autonomous hypersecretion of aldosterone from the adrenal cortex, classically from an adenoma, resulting in sodium and water retention, hypokalaemia and raised blood pressure. The sodium and water retention causes suppression of renin release. The possible cardiac sequelae of ald... |
6,456 | Angiotensin II does not influence expression of sarcoplasmic reticulum Ca2 + ATPase in atrial myocytes. | The sarcoplasmic reticulum Ca(2+) ATPase (SERCA) is essential for the regulation of the intracellular calcium level in cardiomyocytes. Previous studies have found that angiotensin II (Ang II) decreased SERCA2 gene expression in ventricular myocytes. Alteration of SERCA activity is important in the mechanism of atrial f... |
6,457 | Redox modification of ryanodine receptors underlies calcium alternans in a canine model of sudden cardiac death. | Although cardiac alternans is a known predictor of lethal arrhythmias, its underlying causes remain largely undefined in disease settings. The potential role of, and mechanisms responsible for, beat-to-beat alternations in the amplitude of systolic Ca(2+) transients (Ca(2+) alternans) was investigated in a canine post-... |
6,458 | Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents. | In an effort to discover potent, orally bioavailable compounds for the treatment of atrial fibrillation (AF) and ventricular tachycardia (VT), we developed a class of gap-junction modifiers typified by GAP-134 (1, R(1)=OH, R(2)=NH(2)), a compound currently under clinical evaluation. Selected compounds with the desired ... |
6,459 | New pharmacological strategies for the treatment of atrial fibrillation. | Atrial fibrillation (AF) is a growing clinical problem, increasing in prevalence as the population of the United States and countries around the world ages. Intensive research aimed at improving prevention, diagnosis, and treatment of AF is ongoing. Although the use and efficacy of catheter ablation-based approaches in... |
6,460 | Surface ECG characteristics of ventricular tachyarrhythmias before degeneration into ventricular fibrillation in patients with Brugada-type ECG. | This study was designed to evaluate whether the right ventricular outflow tract (RVOT) is the arrhythmogenic focus in Brugada syndrome. We enrolled 45 patients with Brugada-type ECG who underwent programmed ventricular stimulation and inducible ventricular fibrillation (VF). In 25 of these 32 patients, repetitive VT wa... |
6,461 | Blood pressure control and the reduction of left atrial overload is essential for controlling atrial fibrillation. | The purpose of this study was to investigate whether the ideal control of atrial fibrillation (AF) associated with hypertensive patients depends on the usage of renin-angiotensin system (RAS) inhibitors or whether it occurs regardless of the kind of antihypertensive agents used. The control of AF was compared in 112 ou... |
6,462 | Opposing effects of bepridil on ventricular repolarization in humans. Inhomogeneous prolongation of the action potential duration vs flattening of its restitution kinetics. | Bepridil is highly effective in the treatment of atrial fibrillation, but its clinical usefulness is limited by a potential risk for the drug-induced Torsades de pointes (TdP) in association with its Class III action.</AbstractText>Monophasic action potentials (MAPs) were recorded from the right ventricular outflow tra... |
6,463 | Massive systemic air embolism during percutaneous radiofrequency ablation of a primary lung tumor. | We report the case of a systemic air embolism occurring during pulmonary radiofrequency ablation. At the end of the procedure, the patient experienced a sudden myocardial infarction, complicated by ventricular fibrillation, cardiac arrest, and cerebral infarction. Thoracic computed tomography showed an air-blood level ... |
6,464 | Concealed antegrade penetration of the atrio-ventricular node. | We present a patient with paroxysmal, non-sustained atrial tachycardia (AT) on routine surveillance 24-hour Holter post pulmonary vein isolation (PVI). Several asymptomatic ventricular pauses are noted to follow each burst of AT. We postulate that these pauses are due to the resultant concealed penetration of the atrio... |
6,465 | Role of proinflammatory markers and NT-proBNP in patients with an implantable cardioverter-defibrillator and an electrical storm. | Several studies have attempted to identify risk factors for the development of an electrical storm (ES), which is defined as 3 separate ventricular tachyarrhythmic (VT/VF) events, but in the majority of studies no triggers have been found. However, little is known about the role of inflammation and NT-proBNP in patient... |
6,466 | Comparison of efficacy of pulsed biphasic waveform and rectilinear biphasic waveform in a short ventricular fibrillation pig model. | The waveform designs and their relative defibrillation efficacy of external biphasic waveforms may differ remarkably among manufacturers. In this study, we compared pulsed biphasic waveform (PBW) with rectilinear biphasic waveform (RBW) and their effects on terminating ventricular fibrillation (VF).</AbstractText>VF wa... |
6,467 | Basic life support with four different compression/ventilation ratios in a pig model: the need for ventilation. | During cardiac arrest the paramount goal of basic life support (BLS) is the oxygenation of vital organs. Current recommendations are to combine chest compressions with ventilation in a fixed ratio of 30:2; however the optimum compression/ventilation ratio is still debatable. In our study we compared four different comp... |
6,468 | [Iatrogenic risk of permanent pacemaker and defibrillator implantation]. | The considerable evolution in technique and hardware, occurred over the past three decades, has greatly simplified the implantation procedure of pacemakers and cardioverter-defibrillators. Indeed, the introduction of relatively simple and safe methods of central venous access, and the miniaturization of the generator w... |
6,469 | Protective effect of grape seed proanthocyanidins extracts on reperfusion arrhythmia in rabbits. | Reperfusion arrhythmia (RA) is one of the main complications which are also an important cause of sudden cardiac death. The aim of this study was to clarify whether grape seed proanthocyanidins extracts (GSPE) were therapeutic agents against RA. The models of cardiac ischemic reperfusion injury were established in rabb... |
6,470 | Treating myocardial stunning randomly, with either propofol or isoflurane following transient coronary occlusion and reperfusion in pigs. | Propofol and isoflurane may be used during fast track anesthesia for off-pump bypass, where transient ischemia is common. The purpose of this study was to compare the effects of propofol vs isoflurane in a porcine model of acute coronary occlusion. Twenty five pigs were randomized to receive general anesthesia with eit... |
6,471 | Interatrial mechanical dyssynchrony worsened atrial mechanical function in sinus node disease with or without paroxysmal atrial fibrillation. | Atrial electromechanical dysfunction might contribute to the development of atrial fibrillation (AF) in patients with sinus node disease (SND). The aim of this study was to investigate the prevalence and impact of atrial mechanical dyssynchrony on atrial function in SND patients with or without paroxysmal AF.</Abstract... |
6,472 | The value of irbesartan in the management of hypertension. | Elevated blood pressure levels are highly prevalent and are a major reason for cardiovascular events and thus place a significant financial burden on healthcare systems worldwide. Guidelines recommend five first-line anti-hypertensive drug classes, but compelling indications may indicate favoring one drug class over an... |
6,473 | Analysis of surface atrial signals: time series with missing data? | Uncovering of the atrial signal for patients undergoing episodes of atrial fibrillation is usually obtained from surface ECG by removing waves induced by ventricular activities. Once earned the atrial signal, the detection of the dominant fibrillation frequency is often the main (and only) goal. In this work we verifie... |
6,474 | Systematic assessment of patients with unexplained cardiac arrest: Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER). | Cardiac arrest without evident cardiac disease may be caused by subclinical genetic conditions. Provocative testing to unmask a phenotype is often necessary to detect primary electrical disease, direct genetic testing, and perform family screening.</AbstractText>Patients with apparently unexplained cardiac arrest and n... |
6,475 | Low frequency component in systolic arterial pressure variability in patients with persistent atrial fibrillation. | Atrial fibrillation (AF) is a common arrhythmia characterized by irregular ventricular response. During AF, beat-to-beat variability of arterial pressure (AP) is increased because of continuous changes in filling time, stroke volume and contractility. Only a few studies have analyzed short-term AP variability during AF... |
6,476 | A simple automated stimulator of mechanically induced arrhythmias in the isolated rat heart. | Transient stretching of the ventricle can trigger arrhythmias and evoke ventricular fibrillation, especially when the stimulation occurs in the vulnerable period. To explore the sensitivity of small hearts we used a commercial pressure servo to study the kinetic relationship of left ventricular pressure to excitability... |
6,477 | A broad complex tachycardia with conflicting information from pacing manoeuvres. | A patient with a biventricular implantable cardioverter defibrillator for heart failure had a recurrent broad complex tachycardia and underwent electrophysiologic testing. The tachycardia was induced only with ventricular pacing. There was a 1:1 atrioventricular relationship with simultaneous atrial and ventricular act... |
6,478 | Effects of recombinant human granulocyte colony-stimulating factor (filgrastim) on ECG parameters in neutropenic patients: a single-centre, prospective study. | Human granulocyte colony-stimulating factor (G-CSF) is a haematopoietic hormone that promotes the growth, proliferation, differentiation and maturation of neutrophil precursors. Filgrastim is a recombinant human G-CSF. Myocardial infarction, atrial fibrillation and arrhythmia have been reported in several patients with... |
6,479 | Pleiotropic effects of statins in atrial fibrillation patients: the evidence. | Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. The understanding of the pathophysiology of AF has changed during the last several decades, and a significant role of inflammation and of the renin-angiotensin-aldosterone system has been postulated both experimentally and clinically... |
6,480 | Clinical impact of atrial fibrillation in patients with hypertrophic cardiomyopathy. Results from Kochi RYOMA Study. | There have been few studies of the clinical features of hypertrophic cardiomyopathy (HCM) in a community-based patient cohort in Japan.</AbstractText>Cardiomyopathy registration was established in Kochi Prefecture and named the Kochi RYOMA (registry of myocardial diseases) study, consisting of 9 hospitals that register... |
6,481 | Ventricular rhythm in atrial fibrillation under anaesthetic infusion with propofol. | Changes in patients' autonomic tone and specific pharmacologic interventions may modify the ventricular response (actual heart rate) during atrial fibrillation (AF). Hypnotic agents such as propofol may modify autonomic balance as they promote a sedative state. It has been shown that propofol slightly slows atrial fibr... |
6,482 | Response to intravenous ajmaline: a retrospective analysis of 677 ajmaline challenges. | The diagnostic type I ECG in Brugada syndrome (BS) is often concealed and fluctuates between the diagnostic and non-diagnostic pattern. Challenge with intravenous ajmaline is used to unmask the diagnostic Brugada ECG. The aim of this study was to evaluate the safety of the test and to identify predictors for the respon... |
6,483 | Electrophysiological findings in patients with isolated left ventricular non-compaction. | Patients with isolated left ventricular non-compaction (IVNC) are at high risk for developing ventricular tachyarrhythmias. However, no analysis of invasive electrophysiological (EP) findings in these patients has yet been performed.</AbstractText>We performed a retrospective analysis of EP findings in 24 patients with... |
6,484 | The mode of death in the non-heart-beating donor has an impact on lung graft quality. | We hypothesised that the agonal phase prior to cardiac death may negatively influence the quality of the pulmonary graft recovered from non-heart-beating donors (NHBDs). Different modes of death were compared in an experimental model.</AbstractText>Non-heparinised pigs were divided into three groups (n=6 per group). An... |
6,485 | Ventricular tachycardia and ventricular fibrillation.<Pagination><StartPage>801</StartPage><EndPage>809</EndPage><MedlinePgn>801-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1586/erc.09.69</ELocationID><Abstract><AbstractText>Ventricular tachycardia and ventricular fibrillation are the most impo... | Ventricular tachycardia and ventricular fibrillation are the most important causes of sudden cardiac death (SCD), particularly in those with structural heart disease and reduced left ventricular function. It is important to distinguish ventricular tachycardia from supraventricular tachycardia. A wide spectrum of ventri... |
6,486 | Dose-related shortening of ventricular tachycardia cycle length after administration of the KATP channel opener bimakalim in a 4-day-old chronic infarct anesthetized pig model. | Potassium channel openers are known to act on potassium ATP-dependent channels in cardiac tissue. Such agents may exacerbate acceleration of acute ischemia-induced ventricular repolarization and aggravate arrhythmias. To test whether activation of K( ATP) channels during the healing period of myocardial infarction (MI)... |
6,487 | Temporary epicardial ventricular stimulation in patients with atrial fibrillation: acute effects of ventricular pacing site on bypass graft flows. | Data on coronary artery bypass grafts flows in patients with atrial fibrillation (AF) requiring epicardial ventricular pacing is lacking. This study aimed to evaluate the optimal epicardial ventricular pacing site in patients with AF following coronary artery bypass surgery (CABG).</AbstractText>In 23 consecutive patie... |
6,488 | Treatment of asystole and PEA. | Recent reports consistently point to a substantial decline in the incidence of ventricular fibrillation (VF) as the initial rhythm observed by Emergency Medical Service (EMS) responders and a complementary increase in pulseless electrical activity (PEA) and asystole. Historically, efforts at improving survival have foc... |
6,489 | Effect and mechanism of esmolol given during cardiopulmonary resuscitation in a porcine ventricular fibrillation model. | The aim of the study was to investigate the effect on calcium cycling protein and electrical restitution of beta(1)-adrenergic receptor antagonist esmolol administered during cardiopulmonary resuscitation in the porcine ventricular fibrillation model.</AbstractText>Ventricular fibrillation untreated for four minutes wa... |
6,490 | Subarachnoid haemorrhage as a cause of out-of-hospital cardiac arrest: a prospective computed tomography study. | Aneurysmal subarachnoid haemorrhage (SAH) is a relatively common cause of out-of-hospital cardiac arrest (OHCA). Early identification of SAH-induced OHCA with the use of brain computed tomography (CT) scan obtained immediately after resuscitation may help emergency physicians make therapeutic decision as quickly as the... |
6,491 | Isolated ventricular noncompaction mimicking arrhythmogenic right ventricular cardiomyopathy--a study of nine patients. | Isolated ventricular noncompaction is considered to predominantly affect the left ventricle. It is characterized by increased left ventricular wall thickness and deep intertrabecular recesses with to-and-fro blood flow that remains in continuity with the ventricular flow. Aim of the study was to present a group of pati... |
6,492 | Cardiovascular magnetic resonance guided electrophysiology studies. | Catheter ablation is a first line treatment for many cardiac arrhythmias and is generally performed under x-ray fluoroscopy guidance. However, current techniques for ablating complex arrhythmias such as atrial fibrillation and ventricular tachycardia are associated with suboptimal success rates and prolonged radiation ... |
6,493 | Sleep-disordered breathing in patients with atrial fibrillation and normal systolic left ventricular function. | Obstructive sleep apnea (OSA) is more common in patients with atrial fibrillation (AFib). Recently, an additional association between central sleep apnea/Cheyne-Stokes respiration (CSA/CSR) and AFib has been described. The aim of this study was to investigate the prevalence and type of sleep-disordered breathing in pat... |
6,494 | Long-term mortality predictors in patients with chronic bifascicular block. | To evaluate the long-term mortality rate and to determine independent mortality risk factors in patients with bifascicular block (BFB). Patients with BFB are known to have a higher mortality risk than the general population, not only related to progression to atrio-ventricular block but also due to the presence of mali... |
6,495 | A multicentre evaluation of the safety of intracoronary optical coherence tomography. | Optical coherence tomography (OCT) is increasingly being applied to the coronary arteries. However, the risks associated with the imaging procedure are not yet well defined. The purpose of the present multicentre registry was to assess the acute complications associated with the clinical use of intra-coronary OCT in a ... |
6,496 | Predictors of six-month major adverse cardiac events in 30-day survivors after acute myocardial infarction (from the Korea Acute Myocardial Infarction Registry). | Little is known about risk factors for 6-month major adverse cardiac events (MACEs) in 30-day survivors after acute myocardial infarction (AMI). We investigated predictors of 6-month MACE in 30-day survivors after MI from the Korea Acute Myocardial Infarction Registry (KAMIR). From November 2005 to January 2008, 9,706 ... |
6,497 | Ventricular arrhythmia following alcohol septal ablation for obstructive hypertrophic cardiomyopathy. | We sought to assess the risk of sudden cardiac death (SCD) and ventricular arrhythmia after alcohol septal ablation (ASA) for obstructive hypertrophic cardiomyopathy. ASA is a nonsurgical alternative to septal myectomy for treatment of symptomatic, drug-refractory, obstructive hypertrophic cardiomyopathy. The effect of... |
6,498 | [A 10 years review of the characteristics of in-hospital ventricular fibrillation victim in a single center]. | To study the factors influencing the outcome of patients suffering from in-hospital ventricular fibrillation (IHVF), as there have been few studies focusing on this topic.</AbstractText>Patients with IHVF collected in a single cardiac center were classified into a successful group and a failure group. Data relevant to ... |
6,499 | Simultaneous optical mapping of intracellular free calcium and action potentials from Langendorff perfused hearts. | The cardiac action potential (AP) controls the rise and fall of intracellular free Ca2+ (Ca(i)), and thus the amplitude and kinetics of force generation. Besides excitation-contraction coupling, the reverse process where Ca(i) influences the AP through Ca(i)-dependent ionic currents has been implicated as the mechanism... |
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