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6,200 | Endothelin-B receptors and ventricular arrhythmogenesis in the rat model of acute myocardial infarction. | The arrhythmogenic effects of endothelin-1 (ET-1) are mediated via ETA-receptors, but the role of ETB-receptors is unclear. We examined the pathophysiologic role of ETB-receptors on ventricular tachyarrhythmias (VT/VF) during myocardial infarction (MI). MI was induced by coronary ligation in two animal groups, namely i... |
6,201 | Ventricular fibrillation during sport activity successfully treated. | Survival after out-of-hospital cardiopulmonary arrest is estimated at less than 5%. We report a case of ventricular fibrillation during sports activity. Cardiopulmonary resuscitation was initiated early by a layperson, and defibrillation was successfully performed within less than three minutes, with an automated exter... |
6,202 | Ambulatory ECG-based T-wave alternans and heart rate turbulence predict high risk of arrhythmic events in patients with old myocardial infarction. | Few studies have explored risk stratification of arrhythmic events in patients with ischemic heart diseases according to T-wave alternans (TWA) using modified moving average (MMA) method and heart rate turbulence (HRT).</AbstractText>A retrospective analysis of 63 patients who underwent MMA-based TWA and HRT divided th... |
6,203 | Atrial fibrillation and long-term prognosis in patients hospitalized for heart failure: results from heart failure survey in Israel (HFSIS). | Atrial fibrillation (AF) and heart failure (HF) commonly coexist, and each adversely affects the other. The aim of the study was to prospectively evaluate the impact of AF and its subtypes on management, and early and long-term outcome of hospitalized HF patients.</AbstractText>Data were prospectively collected on HF p... |
6,204 | Clinical utility of single-beat E/e' obtained by simultaneous recording of flow and tissue Doppler velocities in atrial fibrillation with preserved systolic function. | We evaluated the usefulness of the ratio of the early diastolic transmitral flow velocity (E) to the mitral annular velocity (e') calculated from simultaneously recorded E and e' in atrial fibrillation (AF).</AbstractText>The ratio of the E to the e' (E/e') has been reported as a useful index even in AF patients. Howev... |
6,205 | Verapamil-associated cardiogenic shock in a 71-year-old man with myasthenia gravis: a case report. | Myasthenia gravis is a rare neuromuscular disorder associated with a reduction in the availability of acetylcholine receptors at the post-synaptic membranes of skeletal muscles. This is caused by the production of anti-acetylcholine receptor antibodies at the neuromuscular junction due to an autoimmune insult, leading ... |
6,206 | Short QT syndrome: a review. | The past 2 decades have witnessed the emergence of many disease states related to ion-channel disorders, the so-called "channelopathies," usually associated with structurally normal hearts. The initial emphasis was directed toward the congenital long QT syndrome and the Brugada syndrome. Recently, the hereditary short ... |
6,207 | 'Orphan drugs' in cardiology: nadolol and quinidine. | The recent withdrawal from the market of nadolol (Corgard; Bristol-Myers Squibb, Sermoneta, Italy) and quinidine polygalacturonate (Ritmocor; Malesci, Bagno A Ripoli, Italy) has been causing clinical problems to many cardiologists and patients, frequently leading to discontinuance of an effective and well-tolerated pha... |
6,208 | Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. | LKB1 encodes a serine/threonine kinase, which functions upstream of the AMP-activated protein kinase (AMPK) superfamily. To clarify the role of LKB1 in heart, we generated and characterized cardiac myocyte-specific LKB1 knock-out (KO) mice using alpha-myosin heavy chain-Cre deletor strain. LKB1-KO mice displayed biatri... |
6,209 | [Cryothermal energy: a new perspective for interventional therapy of cardiac arrhythmias?]. | Cryothermal ablation is a new method in cardiac electrophysiology for the percutaneous catheter ablation of cardiac arrhythmias. Cryothermal mapping make possible the functional assessment of a particular site before permanent ablation. In this way the targeted tissue may be confirmed as safe for ablation. This is usef... |
6,210 | Impact of right ventricular pacing sites on exercise capacity during ventricular rate regularization in patients with permanent atrial fibrillation. | The deleterious effects of right ventricular apical (RVA) pacing may offset the potential benefit of ventricular rate (VR) regularization and rate adaptation during an exercise in patient's atrial fibrillation (AF).</AbstractText>We studied 30 patients with permanent AF and symptomatic bradycardia who receive pacemaker... |
6,211 | The effect of oral methadone on the QTc interval in advanced cancer patients: a prospective pilot study. | Recent reports suggest that high doses of methadone may prolong QTc interval and occasionally cause torsades de pointes; however, few of these studies involved the palliative care population.</AbstractText>The purpose of this study was to determine the effect of initiation of methadone on QTc interval in patients with ... |
6,212 | Safety of symptom-limited cardiopulmonary exercise testing in patients with chronic heart failure due to severe left ventricular systolic dysfunction. | To assess the safety of symptom-limited exercise testing in patients with New York Heart Association class II-IV heart failure symptoms due to left ventricular systolic dysfunction, we investigated the frequency of all-cause fatal and nonfatal major cardiovascular (CV) events among subjects enrolled in a prospective cl... |
6,213 | Electromagnetic interference of communication devices on ECG machines. | Use of communication devices in the hospital environment remains controversial. Electromagnetic interference (EMI) can affect different medical devices. Potential sources for EMI on ECG machines were systematically tested.</AbstractText>Communication devices produce EMI on ECG machines. EMI impairs ECG interpretation.<... |
6,214 | Effect of global ischemia and reperfusion during ventricular fibrillation in myopathic human hearts. | The effect of lack of global coronary perfusion on myocardial activation rate, wavebreak, and its temporal progression during human ventricular fibrillation (VF) is not known. We tested the hypothesis that global myocardial ischemia decreases activation rate and spatiotemporal organization during VF in myopathic human ... |
6,215 | [Recurrent refractory ventricular fibrillation: how many times is it necessary to defibrillate?]. | Recurrent ventricular fibrillation is that which persists after three consecutive defibrillation attempts. It generally appears in almost 25% of all heart arrests and entails high mortality. Use of amiodarone during resuscitation maneuvers is recommended, this having better results than lidocaine. Neither procainamide ... |
6,216 | Ethyl pyruvate enhances intra-resuscitation hemodynamics in prolonged ventricular fibrillation arrest. | As the duration of untreated cardiac arrest increases, the effectiveness of standard therapies declines, and may be more harmful than helpful. We investigated the hemodynamic, metabolic and anti-inflammatory effects of Ringer's ethyl pyruvate solution (REPS) versus Ringer's solution (RS) in the acute model of prolonged... |
6,217 | Vanoxerine, a new drug for terminating atrial fibrillation and flutter. | Vanoxerine produces potent block of cardiac hERG, sodium, and L-type calcium channels. Block is strongly frequency dependent, is unassociated with transmural dispersion of repolarization, and occurs at concentrations safe in humans. Therefore, we proposed that vanoxerine might be antiarrhythmic. In these studies, we te... |
6,218 | Vanoxerine: cellular mechanism of a new antiarrhythmic. | There remains an unmet need for safe and effective antiarrhythmic drugs, especially for the treatment of atrial fibrillation. Vanoxerine is a drug that is free of adverse cardiac events in normal volunteers, yet is a potent blocker of the hERG (hK(v)11.1) cardiac potassium channel. Consequently,we hypothesized that van... |
6,219 | Long-term outcomes of inducible very fast ventricular tachycardia (cycle length 200-250 ms) in patients with ischemic cardiomyopathy. | The long-term outcomes of patients with inducible very fast ventricular tachycardia (VFVT) of cycle length (CL) 200 to 250 ms have not been well studied.</AbstractText>Consecutive patients with ischemic cardiomyopathy with a left ventricular ejection fraction (LVEF) of <or=40% (n = 300) underwent programmed ventricu... |
6,220 | A new electrocardiographic algorithm to locate the occlusion in left anterior descending coronary artery. | Early prediction of proximal left anterior descending coronary artery (LAD) occlusion is essential from a clinical point of view</AbstractText>To develop an electrocardiogram (ECG) algorithm based on ST-segment deviations to predict the location of occlusion of LAD as a culprit artery.</AbstractText>ECG and angiographi... |
6,221 | Alendronate affects calcium dynamics in cardiomyocytes in vitro. | Therapy with bisphosphonates, including alendronate (ALN), is considered a safe and effective treatment for osteoporosis. However, recent studies have reported an unexpected increase in serious atrial fibrillation (AF) in patients treated with bisphosphonates. The mechanism that explains this side effect remains unknow... |
6,222 | Effect of mitral regurgitation on cerebrovascular accidents in patients with atrial fibrillation and left atrial thrombus. | The effect of mitral regurgitation (MR) on the incidence of new cerebrovascular accidents (CVA) and mortality in patients with atrial fibrillation (AF) and left atrial thrombus (LAT) is unknown.</AbstractText>To investigate the effect of MR in patients with AF and LAT on new CVA and mortality.</AbstractText>Eighty nine... |
6,223 | A servo-controlled canine model of stable severe ischemic left ventricular failure. | Reversible left ventricular failure was produced in conscious dogs by compromise of the coronary circulation. In animals with prior left anterior descending coronary artery occlusion, mean left atrial pressure (LAP) was incorporated into an automatic feedback control system used to inflate a balloon cuff on the circumf... |
6,224 | A sweet tooth as the root cause of cardiac arrest. | A 71-year-old woman was admitted with hypotension and bradycardia. An electrocardiogram showed flattened T waves and increased U wave prominence, resulting in a long QT(U) syndrome. Her initial serum potassium level was 1.6 mmol/L (all other electrolytes, including magnesium, were normal). She suffered recurrent ventri... |
6,225 | Prophylactic amiodarone versus lidocaine for prevention of reperfusion ventricular fibrillation after release of aortic cross-clamp. | Ventricular fibrillation is common after aortic cross-clamp release in patients undergoing open-heart surgeries. The aim of the study was to evaluate the efficacy of the prophylactic administration of 150 mg amiodarone by way of the pump 2 min before release of aortic cross-clamp in preventing ventricular fibrillation.... |
6,226 | Simultaneous right and left coronary occlusion caused by an extensive dissection to the coronary sinus of Valsalva during percutaneous intervention in right coronary artery. | We report a case of simultaneous right and left coronary occlusion during percutaneous coronary intervention in the right coronary artery. An aortocoronary dissection induced by the forceful manipulation extended from the right to left sinus of Valsalva and occluded the ostia of both coronary arteries. The patient suff... |
6,227 | Cardiac metabolism and arrhythmias. | Sudden cardiac death remains a leading cause of mortality in the Western world, accounting for up to 20% of all deaths in the U.S., The major causes of sudden cardiac death in adults age 35 and older are coronary artery disease (70–80%) and dilated cardiomyopathy (10–15%). At the molecular level, a wide v... |
6,228 | Prediction of ventricular tachyarrhythmias by intracardiac repolarization variability analysis. | Arrhythmic sudden cardiac death (SCD) is generally mediated by ventricular fibrillation (VF) or fast ventricular tachycardia (FVT). We studied the predictive value of temporal QT variability detected from various sources of cardiac electric signal: surface ECG, far-field (FF), and near-field (NF) intracardiac electrogr... |
6,229 | Long-term improvement in left ventricular strain after successful catheter ablation for atrial fibrillation in patients with preserved left ventricular systolic function. | The effect of successful catheter ablation on left ventricular (LV) strain in patients with preserved LV systolic function is unknown. The aim of the present study was to assess the long-term effects of catheter ablation for atrial fibrillation (AF) on LV strain and strain rate in patients with preserved LV ejection fr... |
6,230 | Preshock cardiopulmonary resuscitation worsens outcome from circulatory phase ventricular fibrillation with acute coronary artery obstruction in swine. | Some clinical studies have suggested that chest compressions before defibrillation improve survival in cardiac arrest because of prolonged ventricular fibrillation (VF; ie, within the circulatory phase). Animal data have also supported this conclusion, and we have previously demonstrated that preshock chest compression... |
6,231 | Absence of pathognomonic or inflammatory patterns in cardiac biopsies from patients with Brugada syndrome. | Brugada syndrome (BrS) is characterized by the presence of coved ST-segment elevations in the right precordial leads (so-called type I ECG) and additional clinical features. Caused by cardiac ion channel gene mutations, BrS may be associated with ventricular and atrial conduction disturbances as well as ventricular fib... |
6,232 | Yield of genetic screening in inherited cardiac channelopathies: how to prioritize access to genetic testing. | Identification of mutations in cardiac ion channel genes concurs to the diagnosis of long-QT syndrome, Brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia. However, because availability of genetic screening is still limited and reimbursement policies are lacking, there is a need of evidence-base... |
6,233 | Incidence of atrial fibrillation in relation to changing heart rate over time in hypertensive patients: the LIFE study. | Onset of atrial fibrillation (AF) has been linked to changes in autonomic tone, with increasing heart rate (HR) immediately before AF onset in some patients suggesting a possible role of acute increases in sympathetic activity in AF onset. Although losartan therapy and decreasing ECG left ventricular hypertrophy are as... |
6,234 | In a swine model, chest compressions cause ventricular capture and, by means of a long-short sequence, ventricular fibrillation. | During resuscitation, fibrillation often recurs. In swine, we studied refibrillation after long-duration ventricular fibrillation, investigating an association with chest compressions (CCs).</AbstractText>In protocol A, 47 episodes of long-duration ventricular fibrillation lasting at least 2.5 minutes were induced in 8... |
6,235 | Association between elevated fibrosis markers and heart failure in the elderly: the cardiovascular health study. | Myocardial fibrosis reflects excess collagen deposition in the extracellular left ventricular matrix, which has been associated with heart failure (HF). No studies have addressed the relation between fibrosis biomarkers and HF in the elderly.</AbstractText>Serum fibrosis markers were measured in 880 participants of the... |
6,236 | The efficacy of implantable cardioverter-defibrillators in heart transplant recipients: results from a multicenter registry. | Sudden cardiac death among orthotopic heart transplant recipients is an important mechanism of death after cardiac transplantation. The role for implantable cardioverter-defibrillators (ICDs) in this population is not well established. This study sought to determine whether ICDs are effective in preventing sudden cardi... |
6,237 | Digoxin therapy does not improve outcomes in patients with advanced heart failure on contemporary medical therapy. | The impact of digoxin on outcomes of patients with advanced heart failure (HF) receiving optimal contemporary therapy is not known.</AbstractText>We retrospectively reviewed data of 455 advanced HF patients referred for transplant evaluation (age, 52+/-12 years; ejection fraction, 18.3+/-8%); 227 (49.9%) were on digoxi... |
6,238 | Management of nonvalvular atrial fibrillation: a comprehensive approach. | Atrial fibrillation is the most common arrhythmia in clinical practice, may coexist with conditions common to both cardiovascular and noncardiovascular diseases and is associated with considerable morbidity and mortality. Atrial fibrillation is often asymptomatic and diagnosed only when it has caused a potentially seri... |
6,239 | Induction and maintenance of in vivo ventricular fibrillation in rabbits. | To provide new sustainable in vivo models of ventricular fibrillation in rabbits.</AbstractText>New Zealand rabbits were submitted to anaesthesia and mechanical ventilation, after which ventricular fibrillation was induced through electrical stimulation (for 2min at 100Hz, with 2-ms pulses, 10mA, and 10V) directly to t... |
6,240 | Predictors of resuscitation outcome in a swine model of VF cardiac arrest: A comparison of VF duration, presence of acute myocardial infarction and VF waveform. | Factors that affect resuscitation to a perfusing rhythm (ROSC) following ventricular fibrillation (VF) include untreated VF duration, acute myocardial infarction (AMI), and possibly factors reflected in the VF waveform. We hypothesized that resuscitation of VF to ROSC within 3min is predicted by the VF waveform, indepe... |
6,241 | The first documented cardiac arrest rhythm in hospitalized patients with heart failure. | Patients with heart failure (HF) have abnormal cellular anatomy and myocardial mechanics that may impact the initial rhythm and subsequent outcomes in cardiac arrest (CA).</AbstractText>Patients with pre-existing HF are less likely to have ventricular fibrillation/pulseless ventricular tachycardia (VF/pVT) as the first... |
6,242 | Chronic augmentation of the parasympathetic tone to the atrioventricular node: a nonthoracotomy neurostimulation technique for ventricular rate control during atrial fibrillation. | The right inferior ganglionated plexus (RIGP) selectively innervates the atrioventricular node. Temporary electrical stimulation of this plexus reduces the ventricular rate during atrial fibrillation (AF). We sought to assess the feasibility of chronic parasympathetic stimulation for ventricular rate control during AF ... |
6,243 | Vernakalant (RSD1235) in the management of atrial fibrillation: a review of pharmacological properties, clinical efficacy and safety. | Vernakalant (RSD1235) is a novel antiarrhythmic agent for conversion of rapid onset atrial fibrillation (AF). It is an atria-selective multichannel ion blocker (blocks I(Kur), I(Na), I(Ca, L), I(to) and I(Kr)), with a small effect on ventricular repolarization. In clinical Phase II and III studies, vernakalant was mode... |
6,244 | In-hospital and long-term prognosis after myocardial infarction in patients with prior coronary artery bypass surgery; 19-year experience. | To present a 19-year experience of the prognosis of patients with acute myocardial infarction (AMI) and prior coronary artery bypass surgery (CABS), 748 patients with AMI after prior CABS (postbypass group) and a control group of 1080 patients with AMI, but without prior CABS, were analyzed. All indexes of infarct size... |
6,245 | Introducing a new entity: chemotherapy-induced arrhythmia. | The relationship between chemotherapy and arrhythmias has not been well established. We reviewed the existing literature to better understand this connection. We reviewed published reports on chemotherapy-induced arrhythmias in English using the PubMed/Medline and OVID databases from 1950 onwards as well as lateral ref... |
6,246 | Isolated left ventricular noncompaction syndrome. | Isolated left ventricular noncompaction (ILVNC) is a rare congenital cardiomyopathy characterized by prominent trabeculae, deep intertrabecular recesses, and thickened myocardium with 2 distinct layers (compacted and noncompacted). Clinical characteristics, outcomes, and appropriate therapies remain poorly defined. Dat... |
6,247 | Amiodarone for the prevention of reperfusion ventricular fibrillation. | The purpose of this study was to evaluate the efficacy of prophylactic single-dose amiodarone administered through the pump circuit before releasing the aortic cross-clamp (ACC) in preventing the occurrence of reperfusion ventricular fibrillation (RVF).</AbstractText>A prospective, randomized double-blind, placebo-cont... |
6,248 | Scn3b knockout mice exhibit abnormal sino-atrial and cardiac conduction properties. | In contrast to extensive reports on the roles of Na(v)1.5 alpha-subunits, there have been few studies associating the beta-subunits with cardiac arrhythmogenesis. We investigated the sino-atrial and conduction properties in the hearts of Scn3b(-/-) mice.</AbstractText>The following properties were compared in the heart... |
6,249 | Surgical outcomes and post-operative changes in patients with significant aortic stenosis and severe left ventricle dysfunction. | Little is known regarding long-term survival and changes in systolic function following surgery after the occurrence of a severe left ventricular (LV) dysfunction in patients with severe aortic stenosis. Inclusion criteria were an aortic valve area less than 1 cm(2) and an LV ejection fraction (EF) less than 35%. Betwe... |
6,250 | Primary prevention of atrial fibrillation: does the atrial lead position influence the incidence of atrial arrhythmias in patients with sinus node dysfunction? Results from the PASTA Trial. | PASTA (pacing of the atria in sinus node disease) is a prospective and randomized trial, assessing the effect of different atrial lead positions on the atrial fibrillation (AF) incidence in patients with sinus node disease (SND).</AbstractText>The atrial lead position is randomized to: (a) free right atrial wall, (b) r... |
6,251 | Model-based control of cardiac alternans on a ring. | Cardiac alternans, a beat-to-beat alternation of cardiac electrical dynamics, and ventricular tachycardia, generally associated with a spiral wave of electrical activity, have been identified as frequent precursors of the life-threatening spatiotemporally chaotic electrical state of ventricular fibrillation (VF). Schem... |
6,252 | [Atrial fibrillation in hypertrophic cardiomyopathy: determinants, clinical course and management]. | Atrial fibrillation (AF) is the most common sustained arrhythmia in patients with hypertrophic cardiomyopathy (HCM), and represents an important complication in the clinical course of the disease, with adverse consequences on functional status and outcome. Studies on community-based HCM patient populations have shown t... |
6,253 | [Prevention of sudden death in hypertrophic cardiomyopathy (HCM ): implanted defibrillators in HCM]. | Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death in young people. The implantable cardioverter-defibrillator (ICD), has recently proved to be a safe and effective therapeutic intervention in patients with HCM, both for the primary and secondary prevention of sudden death. Based on rece... |
6,254 | No assisted ventilation cardiopulmonary resuscitation and 24-hour neurological outcomes in a porcine model of cardiac arrest. | To evaluate the effect of no assisted ventilation cardiopulmonary resuscitation on neurologically intact survival compared with ten positive pressure ventilations/minute cardiopulmonary resuscitation in a pig model of cardiac arrest.</AbstractText>Prospective randomized animal study.</AbstractText>Animal laboratory.</A... |
6,255 | Therapeutic hypothermia (30 degrees C) enhances arrhythmogenic substrates, including spatially discordant alternans, and facilitates pacing-induced ventricular fibrillation in isolated rabbit hearts. | Therapeutic hypothermia (TH, 30 degrees C) protects the brain from hypoxic injury. However, TH may potentiate the occurrence of lethal ventricular fibrillation (VF), although the mechanism remains unclear. The present study explored the hypothesis that TH enhances wavebreaks during VF and S(1) pacing, facilitates pacin... |
6,256 | Brain natriuretic peptide for the prediction of sudden cardiac death and ventricular arrhythmias: a meta-analysis. | The risk stratification of patients for sudden cardiac death (SCD) remains a challenge. Brain natriuretic peptide (BNP) predicts overall mortality in heart disease but it is unclear how well it predicts SCD. We therefore performed a meta-analysis of studies evaluating the accuracy of BNP to predict SCD and ventricular ... |
6,257 | [Mild therapeutic hypothermia following resuscitation; experience and results in the first two years after introduction]. | To describe the results of mild therapeutic hypothermia (MTH) following resuscitation in the 'Gelderse Vallei' hospital, Ede, the Netherlands.</AbstractText>Descriptive, retrospective.</AbstractText>Patient data was collected from patients who had undergone MTH during the first two years following introduction of this ... |
6,258 | [How to improve response to cardiac resynchronization therapy?]. | Cardiac resynchronization therapy decreases mortality and rehospitalization for heart failure. However, around 30% of patients do not respond to this therapy. The paper analyses factors, with a possible impact on the response to this therapy. It is a left ventricular lead proximity to the left ventricle segment with th... |
6,259 | Late gadolinium enhancement in cardiovascular magnetic resonance in patients with hypertrophic cardiomyopathy complicated by life-threatening ventricular tachyarrhythmia. | Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) has been shown to be associated with ventricular arrhythmias, however, its prognostic role in predicting sudden cardiac death has not yet been established.</AbstractText>To explore a potential relationship between LGE visualised by CMR and li... |
6,260 | [Life-threatening ventricular arrhythmia during simultaneous administration of propafenone and sotatol]. | A case of a patient treated with antiarrhythmic drugs for ventricular arrhythmia occurring after viral infection of the respiratory tract is presented. In the course of preliminary cardiologic examination no organic heart disease was diagnosed. Due to numerous ventricular extrasystolic beats (16,500 per day) and short ... |
6,261 | Recurrence of ventricular arrhythmias in patients with non-ischaemic dilated cardiomyopathy: evidence-based predictors. | Ventricular arrhythmia (VA) is the most frequent cause of sudden death among patients with non-ischaemic dilated cardiomyopathy (DCM).</AbstractText>To identify the important VA risk factors in patients with DCM.</AbstractText>Eighty-five DCM patients (73 males, mean age 54 years) with DCM and implantable cardioverter ... |
6,262 | Graft fixation with a side graft holder for sequential and composite graft anastomosis in coronary artery bypass surgery. | The purpose of this study was to assess the feasibility and effectiveness of graft fixation with a novel side graft holder for sequential or composite graft anastomosis in coronary artery bypass grafting (CABG). Records of 34 patients who underwent CABG using sequential or composite graft anastomosis technique were rev... |
6,263 | Case of transient mid-ventricular ballooning syndrome with a rapid and uncommon recovery. | A 60-year-old woman presented with acute pulmonary edema followed by cardiopulmonary arrest due to idiopathic ventricular fibrillation. Owing to immediate cardioversion, her electrocardiogram showed sinus rhythm and echocardiography did not show any wall motion abnormalities. The next day, echocardiographic re-examinat... |
6,264 | Repair of left ventricular aneurysm: ten-year experience in Chinese patients. | A large transmural myocardial infarction often results in a dyskinetic or akinetic left ventricular aneurysm (LVA). This study aimed to explore the early and long-term clinical outcomes and to identify predictors for survivals and hospital re-admission after the repair of left ventricular aneurysm.</AbstractText>We fol... |
6,265 | [Clinical characteristics and treatment of a Chinese family with congenital short QT syndrome.]. | To observe the clinical characteristics and therapeutic efficacy of a Chinese family with congenital short QT Syndrome (SQTs).</AbstractText>Fourteen family members including the proband were screened with routine clinical examination, serum electrolyte, serum myocardial enzymes, electrocardiography (ECG), Holter recor... |
6,266 | [Brugada syndrome--a brand new case]. | Brugada syndrome (BS) is a disorder characterized by syncope or sudden death associated with one of several electrocardiographic (ECG) patterns characterized by incomplete right bundle branch block and ST elevation in the anterior precordial leads. Patients with BS are prone to develop ventricular tachyarrhythmias that... |
6,267 | [Clinical and prognostic significance of left bundle branch block in patients with severe chronic heart failure]. | Clinical and prognostic significance of left bundle branch block (LBBB) was investigated in 62 elderly patients with severe chronic heart failure (CHF). In comparison to 93 patients with CHF but without intra-ventricular blocks patients with LBBB demonstrated more frequently atrial fibrillation and left ventricular sys... |
6,268 | Rate of progression and functional significance of aortic root calcification after homograft versus freestyle aortic root replacement. | Calcification is an important limitation after aortic root replacement. The aims were to compare the long-term degree and rate of calcification of homografts versus Medtronic freestyle aortic roots to determine the functional consequences and predictive factors.</AbstractText>One hundred sixty-six patients were prospec... |
6,269 | Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion. | Hypercholesterolemia is prevalent in patients who experience myocardial ischemia-reperfusion injury (IR). We investigate the impact of dietary-induced hypercholesterolemia on the myocardium in the setting of acute IR.</AbstractText>In normocholesterolemic (NC, n=7) and hypercholesterolemic (HC, n=7) Yucatan male pigs, ... |
6,270 | Organ donation after cardiac determination of death (DCD): a swine model. | Donors after Cardiac Death (DCD) may reduce the organ scarcity; however, their use is limited because of warm ischemia time. Fortunately, this is less important in a subclass of DCD called expected (e-DCD), those with irreversible but incomplete brain injury. This study analyzed hemodynamic/pulmonary data to establish ... |
6,271 | Rhythms and outcomes of adult in-hospital cardiac arrest. | To determine the relationship of electrocardiographic rhythm during cardiac arrest with survival outcomes.</AbstractText>Prospective, observational study.</AbstractText>Total of 411 hospitals in the National Registry of Cardiopulmonary Resuscitation.</AbstractText>Total of 51,919 adult patients with pulseless cardiac a... |
6,272 | Active surface cooling protocol to induce mild therapeutic hypothermia after out-of-hospital cardiac arrest: a retrospective before-and-after comparison in a single hospital. | To evaluate whether implementation of a therapeutic hypothermia protocol on arrival in a community hospital improved survival and neurologic outcomes in patients initially found to have ventricular fibrillation, pulseless electrical activity, or asystole, and then successfully resuscitated from out-of-hospital cardiac ... |
6,273 | Assessment of CPR-D skills of nursing students in two institutions: reality versus recommendations in the guidelines. | Significant differences in basic life support skills including cardiopulmonary resuscitation and defibrillation (CPR-D) were detected when nurses working in one Finnish and one Swedish hospital were tested using an Objective Structured Clinical Examination (OSCE). The purpose of this study was to use OSCE test in asses... |
6,274 | Neuronal nitric oxide synthase protects against myocardial infarction-induced ventricular arrhythmia and mortality in mice. | Neuronal nitric oxide synthase (nNOS) is expressed in cardiomyocytes and plays a role in regulating cardiac function and Ca2+ homeostasis. However, the role of nNOS in cardiac electrophysiology after myocardial infarction (MI) is unclear. We hypothesized that nNOS deficiency increases ventricular arrhythmia and mortali... |
6,275 | Left atrial remodelling in hypertrophic cardiomyopathy: relation with exercise capacity and biochemical markers of tissue strain and remodelling. | Left atrial remodelling, assessed as left atrial volume (LAV), has been proposed as a good marker of left ventricular diastolic dysfunction. The aim of this study was to analyse the influence of LAV on exercise performance in hypertrophic cardiomyopathy (HCM), and in a subset of subjects, assess the relation of LAV and... |
6,276 | [Progress in antiarrhythmic therapy]. | The number of patients with cardiac arrhythmias is increasing in our society with the aged people along with hypertension, diabetes mellitus, metabolic syndrome and ischemic heart diseases. Patient characteristics and therapeutic tools are both diverse at present, and, therefore, clinical evidence is one of the importa... |
6,277 | Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemia-reperfusion. | We tested the effect of the antianginal agent ranolazine on ventricular arrhythmias in an ischemic model using two protocols. In protocol 1, anesthetized rats received either vehicle or ranolazine (10 mg/kg, iv bolus) and were subjected to 5 min of left coronary artery (LCA) occlusion and 5 min of reperfusion with elec... |
6,278 | Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress. | Oxidative stress with hydrogen peroxide (H(2)O(2)) readily promotes early afterdepolarizations (EADs) and triggered activity (TA) in isolated rat and rabbit ventricular myocytes. Here we examined the effects of H(2)O(2) on arrhythmias in intact Langendorff rat and rabbit hearts using dual-membrane voltage and intracell... |
6,279 | Frequencies and types of arrhythmias in patients with systemic light-chain amyloidosis with cardiac involvement undergoing stem cell transplantation on telemetry monitoring. | Cardiac patients with systemic light-chain amyloidosis have a high incidence of arrhythmias and arrhythmia-related death. We aimed to describe the arrhythmias, determine patient characteristics associated with the development of ventricular arrhythmias, and the utility of telemetric monitoring in patients with cardiac ... |
6,280 | Association of the parameters derived from the relation between RR intervals and left ventricle performance with a history of heart failure in patients with atrial fibrillation. | Parameters derived from the relation between RR intervals and left ventricular (LV) performance in atrial fibrillation (AF) have been useful to evaluate systolic LV function. This study investigated the association of these parameters with a history of heart failure. Echocardiography was performed in 107 patients with ... |
6,281 | Association of left atrial strain and strain rate assessed by speckle tracking echocardiography with paroxysmal atrial fibrillation. | We hypothesized that contraction of the LA wall could be documented by speckle tracking and could be applied for assessment of LA function. This study tried to identify the association between LA longitudinal strain (LAS) and strain rate (LASR) measured by speckle tracking with paroxysmal atrial fibrillation (PAF).</Ab... |
6,282 | Persistent ventricular asynchrony after coronary artery bypass surgery predicts cardiac events. | The aim of this study was to identify echocardiographic LV systolic and diastolic measurements that predict clinical events post-coronary artery bypass graft (CABG) surgery.</AbstractText>We collected data from 27 patients (age 70 +/- 7 years) who underwent elective CABG, before and within 6 weeks after surgery. LV sys... |
6,283 | Ventricular mechanical asynchrony in patients with different degrees of systolic dysfunction: results from AVE Registry by the Italian Society of Cardiovascular Echography (SIEC). | The aim of the study was to compare the prevalence of interventricular and intraventricular asynchrony in patients with different degrees of left ventricular (LV) dysfunction.</AbstractText>We enrolled 182 patients (male 79%, mean age 64 +/- 11 years) with LV ejection fraction (EF) < 50% and identified two groups: G... |
6,284 | Sex differences in cerebral injury after severe haemorrhage and ventricular fibrillation in pigs. | Experimental studies of haemorrhagic shock have documented a superior haemodynamic response and a better outcome in female animals as compared with male controls. Such sexual dimorphism has, nevertheless, not been reported after circulatory arrest that follows exsanguination and shock. We aimed to study differences in ... |
6,285 | [Reoperation through right thoracotomy for mitral regurgitation after coronary artery bypass grafting; report of a case]. | A 53-year-old male patient developed severe mitral regurgitation 6 years after coronary artery bypass grafting (CABG) with a left internal thoracic artery and 2 saphenous veins. The left ventriculography showed severe mitral regurgitation and slight decrease in left ventricular function. The coronary arteriography show... |
6,286 | Vulnerability to unidirectional conduction block and reentry in rabbit left ventricular wedge preparation: effects of stimulation sequence and location. | Many factors influence the initiation of unidirectional conduction block and reentry. To explore the influential factors on the temporal vulnerable window of the unidirectional conduction block, we investigated the effect of stimulation sequence and location on the temporal vulnerability in epicardial and endocardial s... |
6,287 | Predicting successful pulmonary vein isolation in patients with atrial fibrillation by brain natriuretic Peptide plasma levels. | Catheter ablation for atrial fibrillation is a clinically established treatment by now while success rate varies between 60% and 85%. Interventional treatment of atrial fibrillation is still a challenging technique associated with a long procedure time and risk of major complications in up to 6 % of treated patients. T... |
6,288 | A prediction model for out-of-hospital cardiopulmonary resuscitation. | We created a prediction model to be used in cardiopulmonary resuscitation (CPR) attempts as a decision tool to omit futile CPR attempts and to save resources.</AbstractText>In this post hoc analysis, we assessed predictive parameters for neurological recovery after successful CPR. The original study was designed as a b... |
6,289 | Detection of ventricular fibrillation using empirical mode decomposition and Bayes decision theory. | Ventricular fibrillation (VF) is the most serious variety of arrhythmia which requires quick and accurate detection to save lives. In this paper, we propose an empirical mode decomposition (EMD) based algorithm for VF detection. The intrinsic mode functions (IMFs) of VF are orthogonal whereas the lower order IMFs of no... |
6,290 | Myocardial ischemia with left ventricular outflow obstruction. | We report an unusual case of a 32-year old man who was treated for a hypertrophic obstructive cardiomyopathy (HOCM) with a DDD pacing with short AV delay reduction in the past. Without prior notice the patient developed ventricular fibrillation and an invasive cardiac diagnostic was performed, which revealed a myocardi... |
6,291 | Prevention of inappropriate ICD shocks in patients with Brugada syndrome. | In Brugada syndrome implantable cardioverter defibrillator (ICD) therapy is associated with a high rate of inappropriate therapies, mainly due to supraventricular tachyarrhythmias (SVT) (2.7-14.1%/year). Aim of the present study was to evaluate a single ventricular fibrillation (VF) detection zone with a high cut-off r... |
6,292 | Echo Doppler guidance for atrial fibrillation ablation: recognition of primary electropathy. | Atrial fibrillation (AF) is a multivariable disease. Young patients with paroxysmal AF without structural cardiac abnormality ("lone AF") likely have a primary electropathy with excellent results from radiofrequency ablation. However, with persistent AF with cardiac abnormalities, including left atrial enlargement and ... |
6,293 | [Atrial pacing for prevention of atrial fibrillation. Influence of septal atrial pacing, atrial overdrive and AV-delay-optimization on atrial fibrillation burden]. | Atrial overdrive and optimized interatrial conduction time can reduce atrial fibrillation (AF). Increased ventricular stimulation results in a higher incidence of atrial fibrillation.</AbstractText>In 25 patients with paroxysmal AF, a dual-chamber pacemaker (Identity DR 5370, St. Jude Medical) was implanted. Atrial lea... |
6,294 | Racial differences in survival after in-hospital cardiac arrest. | Racial differences in survival have not been previously studied after in-hospital cardiac arrest, an event for which access to care is not likely to influence treatment.</AbstractText>To estimate racial differences in survival for patients with in-hospital cardiac arrests and examine the association of sociodemographic... |
6,295 | Is there a role for digoxin in atrial fibrillation without heart failure? | Digoxin remains one of the most frequently prescribed drugs in the management of atrial fibrillation. The main indications for digoxin in atrial fibrillation are restoration of sinus rhythm, prevention of recurrence and slowing of the ventricular rate. However, none of these effects of digoxin have been confirmed in pl... |
6,296 | Inappropriate cardioverter-defibrillator discharge continues to be a major problem in clinical practice. | The purpose of this study was to determine the rate and causes of inappropriate rhythm detection, and to compare adequacy of ventricular arrhythmia detection by single-chamber and dual-chamber cardioverter-defibrillators (ICD).</AbstractText>We evaluated 190 patients (age 57.2 +/- 11.2 years) with ICD.</AbstractText><A... |
6,297 | Chest compression fraction determines survival in patients with out-of-hospital ventricular fibrillation. | Quality cardiopulmonary resuscitation contributes to cardiac arrest survival. The proportion of time in which chest compressions are performed in each minute of cardiopulmonary resuscitation is an important modifiable aspect of quality cardiopulmonary resuscitation. We sought to estimate the effect of an increasing pro... |
6,298 | Extracellular matrix remodeling in atrial fibrosis: mechanisms and implications in atrial fibrillation. | Atrial fibrosis has been strongly associated with the presence of heart diseases/arrhythmias, including congestive heart failure (CHF) and atrial fibrillation (AF). Inducibility of AF as a result of atrial fibrosis has been the subject of intense recent investigation since it is the most commonly encountered arrhythmia... |
6,299 | Combination pharmacotherapy in the treatment of experimental cardiac arrest. | Full recovery after cardiopulmonary resuscitation (CPR) is poor. We hypothesized that the coadministration of epinephrine, a beta-blocker such as atenolol, and a calcium sensitizer such as levosimendan during CPR would improve survival and postresuscitation myocardial function.</AbstractText>Ventricular fibrillation wa... |
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