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7,400 | Specific and gender differences between hospitalized and out of hospital mortality due to myocardial infarction. | In this paper, the authors evaluate gender related differences of myocardial infarction mortality before and after hospital admittance. Myocardial infarction mortality in the Clinical Hospital Split in the seven years period between 2000 and 2006, have been analyzed together with out of hospital sudden death patients w... |
7,401 | Superiority of biphasic over monophasic defibrillation shocks is attributable to less intracellular calcium transient heterogeneity. | The purpose of this study was to test the hypothesis that superiority of biphasic waveform (BW) over monophasic waveform (MW) defibrillation shocks is attributable to less intracellular calcium (Ca(i)) transient heterogeneity.</AbstractText>The mechanism by which BW shocks have a higher defibrillation efficacy than MW ... |
7,402 | Constrictive pericarditis impressing and narrowing the ascending aorta. | A 77-year-old male patient was admitted to our institution with 1-year history of progressive dyspnea on exertion, and lower extremity edema. His chest x-ray showed a circumferential pericardial calcification and right-sided pleural effusion. The electrocardiography revealed atrial fibrillation with low voltage in all ... |
7,403 | Predictors of secondary tricuspid regurgitation after left-sided valve replacement. | To evaluate the risk factors of tricuspid regurgitation (TR) after left-sided valve replacement (LSVR) and plan the initial surgical treatment of TR.</AbstractText>Two hundred and forty-eight patients, including 217 patients in the LSVR group and 31 patients in the LSVR+DeVega group, were followed up. A retrospective a... |
7,404 | Brugada syndrome in an active duty Air Force senior pilot. | Brugada syndrome describes a subgroup of patients at risk for polymorphic ventricular tachycardia, ventricular fibrillation, and sudden cardiac death and is likely underdiagnosed among aviators.</AbstractText>A 40-year-old male pilot presented to the clinic for his physical. He denied any symptoms on initial questionin... |
7,405 | Induced ion currents and the endothelin pathway as targets for anti-arrhythmic agents. | The development of novel anti-arrhythmic drugs is necessary, specifically agents that do not cause torsades de pointes (Tdp). Ion channelopathy that is involved in mechanisms underlying sudden cardiac death (SCD) includes both ion channels in the membrane, and the calcium-releasing channels and the calcium uptake proce... |
7,406 | Sibutramine-associated QT interval prolongation and cardiac arrest. | To report on a probable association between sibutramine and QT interval prolongation leading to ventricular fibrillation and cardiac arrest.</AbstractText>A previously well 51-year-old woman with obesity but no other relevant past medical history or cardiac risk factors was prescribed sibutramine (initial dose 10 mg da... |
7,407 | Dynamic mechanism for initiation of ventricular fibrillation in vivo. | Dynamically induced heterogeneities of repolarization may lead to wave-front destabilizations and initiation of ventricular fibrillation (VF). In a computer modeling study, we demonstrated that specific sequences of premature stimuli maximized dynamically induced spatial dispersion of refractoriness and predisposed the... |
7,408 | Early sustained ventricular arrhythmias complicating acute myocardial infarction. | Sustained ventricular arrhythmias complicate 2% to 20% of acute myocardial infarctions (MIs) and are associated with increased in-hospital mortality. However, it remains unclear whether successful mechanical revascularization improves outcomes in these patients. The objective of this analysis was to identify predictors... |
7,409 | Paroxysmal ventricular tachycardia and paroxysmal atrial fibrillation associated with subclinical hyperthyroidism, chronic renal failure and elevation of prostate-specific antigen during acute myocardial infarction. | Subclinical hyperthyroidism is an increasingly recognized entity that is defined as a normal serum free thyroxine and free triiodothyronine levels with a thyroid-stimulating hormone level suppressed below the normal range and usually undetectable. Paroxysmal atrial fibrillation is a frequent complication of acute myoca... |
7,410 | Coupled pacing reverses the effects of persistent atrial fibrillation on the left ventricle. | Recent studies have demonstrated that ventricular rate control is a viable treatment strategy for patients in atrial fibrillation (AF). The purpose of this study was to determine whether or not the benefits of coupled pacing (ie, a proposed rate control therapy) could be used during persistent AF.</AbstractText>Six mon... |
7,411 | Arrhythmia surgery in patients with and without congenital heart disease. | Arrhythmia surgery has favorably impacted the clinical course of debilitating atrial and ventricular arrhythmias in patients with and without congenital heart disease. This study reviews arrhythmia mechanisms and documents long-term outcome of patients undergoing arrhythmia operations alone or associated with congenita... |
7,412 | Long-term assessment of electrocardiographic and echocardiographic findings in Norwegian elite endurance athletes. | The long-term outcome and clinical significance of athlete's heart has been debated and more longitudinal data are needed. We present a prospective 15 years' follow-up study of ECG and echo findings in elite endurance athletes following the end of their competitive career.</AbstractText>Clinical evaluation, ECG, ambula... |
7,413 | Functional tricuspid regurgitation in patients with pulmonary hypertension: is pulmonary artery pressure the only determinant of regurgitation severity? | Pulmonary hypertension is a common cause of functional tricuspid regurgitation (TR), but other factors play a role in determining TR severity. The objectives of our study were to determine the distribution of TR severity in relation to pulmonary artery systolic pressure (PASP) and to define the determinants of TR sever... |
7,414 | National Registry on Cardiac Electrophysiology--2006. | Clinical electrophysiology is one of the areas of cardiology that has seen most growth in Portugal, particularly in interventional cardiology, which includes ablation of arrhythmias and prevention of sudden cardiac death. The annual publication of a national registry enables us to assess qualitative and quantitative pr... |
7,415 | Selective site pacing: rationale and practical application. | Although it has become traditional to place permanent pacemaker leads at the right ventricular apex and right atrial appendage, pacing from these locations poorly mimics normal physiology. A growing evidence base shows that right ventricular apical pacing results in ventricular dyssynchrony and various adverse effects.... |
7,416 | Short-coupled variant of torsade de pointes. | A 36-year-old man with a history of primary sclerosing cholangitis and epilepsy was admitted to our hospital for cholangitis. During admission he was resuscitated because of ventricular fibrillation. ECGs showed multiple ventricular premature beats (VPBs) with a short coupling interval (240 ms), resulting in frequent t... |
7,417 | Recurrence of cardiac arrest after 14 years without ICD interventions: a VF cluster immediately after delivery. | One day after childbirth, a 29-year-old woman had several episodes of polymorphic ventricular tachycardia and ventricular fibrillation. She was rescued by an internal cardioverter defibrillator (ICD) which she had received 14 years ago, after out-of-hospital cardiac arrest, without recurrences until now. The electrocar... |
7,418 | Aborted sudden cardiac death in a 52-yearold man without structural heart disease. | Sudden cardiac death in the absence of apparent structural heart disease is an uncommon phenomenon. The majority of these patients do not have 'normal' hearts and specific diagnostic tools are required to identify structural or functional abnormalities. We describe the history of a 50-yearold man who survived ventricul... |
7,419 | Treatment of atrial fibrillation and atrial flutter: Part II. | Atrial fibrillation (AF) is often complicated by a life-threatening ventricular response, and emergency electrocardioversion and/or drug therapy to reduce the rapid ventricular rate may be necessary. However, patients with AF and Wolff-Parkinson-White syndrome should not be given digoxin or calcium channel blockers. El... |
7,420 | Cardiac manifestations following electrocution in children. | Electrical injury can result in a variety of cardiac abnormalities. We evaluate the cardiac effects in patients injured by electric shock and treated in our medical centre.</AbstractText>We reviewed retrospectively the findings in 52 children, aged from 7 months to 17 years, with a mean age of 10.1 +/- 5.1 years, all e... |
7,421 | A simple way to decompress the left ventricle during venoarterial bypass. | The aim of this investigation was to improve the hemodynamics during venoarterial bypass by remote decompression of the left ventricle (LV).</AbstractText>Venoarterial bypass was established in 5 bovine experiments (69+/-10 kg) by the transjugular insertion of a self-expanding cannula (smartcanula) with return through ... |
7,422 | Malignant idiopathic ventricular fibrillation "cured" by radiofrequency ablation. | Idiopathic Ventricular Fibrillation is a rare cause of sudden cardiac death. It may be difficult to prospectively diagnose idiopathic ventricular fibrillation due to the episodic nature of the arrhythmias as well as the inability to induce the clinical tachycardia on electrophysiological studies. Although an implantabl... |
7,423 | [Amiodaron for treatment of perioperative cardiac arrythmia: a broad spectrum antiarrythmetic agent?]. | Cardiac arrhythmias are a common problem in the perioperative period. The incidence found in the current literature varies depending on the population studied and the definition of arrhythmia used. Overall supraventricular arrhythmias, namely atrial fibrillation, are the most common form. Because of its broad spectrum ... |
7,424 | Standard basic life support vs. continuous chest compressions only in out-of-hospital cardiac arrest. | The importance of ventilations after cardiac arrest has been much debated recently and eliminating mouth-to-mouth ventilations for bystanders has been suggested as a means to increase bystander cardiopulmonary resuscitation (CPR). Standard basic life support (S-BLS) is not documented to be superior to continuous chest ... |
7,425 | The clinical course and risk in patients with pseudo-Mahaim fibers. | Pseudo-Mahaim (AP-M) fibers are a rare variant of atrioventricular (AV) accessory pathways. Atriofascicular and atrioventricular accessory connections are characterized by slow conduction and decremental properties. Dual physiological AV node pathways, slow and fast, are observed in a large number of patients with AP-M... |
7,426 | Prognostic value of Holter monitoring in congestive heart failure. | Congestive heart failure (CHF) is an increasingly widespread, costly and deadly disease, frequently named as epidemics of the 21 century. Despite advancement in modern treatment, mortality rate in CHF patients remains high. Therefore, risk stratification in patients with CHF remains one of the major challenges of conte... |
7,427 | Use of cardiac resynchronization therapy in patients hospitalized with heart failure. | The frequency and characterization of patients receiving cardiac resynchronization therapy (CRT) are largely unknown since the publication of pivotal clinical trials and subsequent incorporation of CRT into the American College of Cardiology/American Heart Association guidelines for heart failure.</AbstractText>We anal... |
7,428 | Increased risk of stroke in patients with coronary artery disease and sleep apnea: a 10-year follow-up. | The effect of sleep apnea on mortality and cardiovascular morbidity is mainly unknown. We aimed to study whether sleep apnea is related to stroke, death, or myocardial infarction in patients with symptomatic coronary artery disease.</AbstractText>A total of 392 men and women with coronary artery disease referred for co... |
7,429 | The cardiac sodium channel mutation delQKP 1507-1509 is associated with the expanding phenotypic spectrum of LQT3, conduction disorder, dilated cardiomyopathy, and high incidence of youth sudden death. | We report diverse phenotypic consequences of the delQKP-1507-1509 cardiac sodium channel mutation in three generations of a Chinese family.</AbstractText>Clinical and electrocardiographic (ECG), echocardiographic examination was followed by direct sequencing of SCN5A, KCNQ1, HERG, and LAMIN A/C to screen genomic DNA fr... |
7,430 | Experience of percutaneous mechanical mitral commissurotomy using metallic commissurotome in patients with mitral stenosis at chest disease institute. | Percutaneous metallic mitral commissurotomy (PMMC) has been accepted as an alternative to the traditional balloon technique. The advantage of the metallic commissurotome is that it is designed for several reuse and resterization and it is an interesting tool as seen by the authors.</AbstractText>To evaluate the efficac... |
7,431 | Postoperative oral amiodarone versus oral bisoprolol as prophylaxis against atrial fibrillation after coronary artery bypass graft surgery: a prospective randomized trial. | Postoperative atrial fibrillation (AF) occurs in up to 50% of patients undergoing coronary artery bypass (CABG) surgery and is associated with complications. Amiodarone and beta blockers are effective as prophylaxis for AF after CABG. The purpose of this study was to compare oral amiodarone versus oral bisoprolol for p... |
7,432 | Surgical left atrial appendage occlusion: evaluation of a novel device with magnetic resonance imaging. | Management of the left atrial appendage (LAA) is considered an important adjunct to ablation in cardiac surgical patients with atrial fibrillation (AF). However, current surgical techniques, both cut-and-sew and stapling, have been associated with incomplete LAA occlusion and complications. Using cardiac magnetic reson... |
7,433 | Ventricular arrhythmias in Chronic Chagas' Myocardiopathy: a case report and brief review of different antiarrhythmic strategies. | Management of ventricular arrhythmias due to Chronic Chagas' Myocardiopathy (CCM) is challenging. We present a case of CCM complicated with ventricular tachycardia (VT), and a brief review focused on VT management in this occidental emergent entity. |
7,434 | Determinants of early decline in ejection fraction after surgical correction of mitral regurgitation. | We sought to echocardiographically examine the early changes in left ventricular size and function after mitral valve repair or replacement for mitral regurgitation caused by leaflet prolapse.</AbstractText>Preoperative and early postoperative echocardiograms of 861 patients with mitral regurgitation caused by leaflet ... |
7,435 | Cell membrane stretch and chest blow-induced ventricular fibrillation: commotio cordis. | Commotio cordis, sudden cardiac death secondary to blunt nonpenetrating chest blows in sports, is reported with increasing frequency. In a swine model, ventricular fibrillation (VF) is induced by a baseball blow to the chest, and the initiation of VF is related to the peak left ventricular (LV) pressure produced by the... |
7,436 | QT prolongation and safety in the Indian population. | The QT interval in electrocardiogram (ECG) reflects the total duration of ventricular myocardial depolarization and repolarization. It has been well recognized that many condition may cause QT interval prolongation. Unfortunately, numbers of cardiac and non-cardiac drug prolong the QT interval and cause a distinctive p... |
7,437 | [Sotalol prevents atrio-ventricular tachycardia but not atrial fibrillation with rapid ventricular response in a patient wiht WPW syndrome]. | We present a case of 23-year-old male with the Marfan syndrome multiple accessory pathways and atrio-ventricular reentry ant tachycardia (AVRT) as well as atrial fibrillation (AF). Sotalol was partially effective for AVRT, however, it did not prevent AF, RF ablation cured all arrythmias. This case shows that sotalol ca... |
7,438 | Relationship between inflammatory markers and clinical patterns of atrial fibrillation in patients with congestive heart failure. | Occurence of atrial fibrillation (AF) adversely affects left atrial size and cardiac function. This arrhythmia is also associated with an increase of plasma CRP and fibrinogen concentration. It is not clear whether elevated levels of inflammatory markers in patients with congestive heart failure (CHF) are associated wi... |
7,439 | Atrial fibrillation down-regulates renal neutral endopeptidase expression and induces profibrotic pathways in the kidney. | Recent studies suggest that atrial fibrillation (AF) substantially influences microvascular flow in ventricular myocardium. This process may contribute to the occurrence of heart failure in AF. In general, development of heart failure and renal dysfunction go hand-in-hand causing systemic fluid overload and oedema. So ... |
7,440 | Optimal transvenous coil position on active-can single-coil ICD defibrillation efficacy: a simulation study. | The implantable cardioverter defibrillator with an active can and a single coil lead is effective in treating ventricular fibrillation, but the lead placement associated with the high defibrillation efficacy is still controversial and remains largely empirical. In this study, an anatomically realistic finite difference... |
7,441 | Long-term predictors of mortality in ICD patients with non-ischaemic cardiac disease: impact of renal function. | Randomized trials have demonstrated that implantable cardioverter defibrillator (ICD) therapy may reduce the risk of death in patients with non-ischaemic cardiomyopathy (CMP). In this study, we aimed at determining the long-term benefit of ICD therapy among patients with dilated CMP (DCM) and among those with other non... |
7,442 | Ventricular fibrillation in King County, Washington: a 30-year perspective. | We determined the effect of four major program changes over a 30-year period on survival from witnessed cardiac arrest (CA) with ventricular fibrillation (VF) as the rhythm causing collapse.</AbstractText>We conducted an investigation of emergency medical services (EMS)-treated CA occurring between 1978 and 2007. Data ... |
7,443 | No benefit from defibrillation threshold testing in the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial). | This study investigated whether defibrillation threshold (DFT) testing during implantable cardioverter-defibrillator (ICD) implantation predicts clinical outcomes.</AbstractText>Defibrillation testing is often performed during insertion of ICDs to confirm shock efficacy. There are no prospective data to suggest that th... |
7,444 | Strategic programming of detection and therapy parameters in implantable cardioverter-defibrillators reduces shocks in primary prevention patients: results from the PREPARE (Primary Prevention Parameters Evaluation) study. | Our purpose was to demonstrate that strategically chosen implantable cardioverter-defibrillator (ICD) ventricular tachycardia (VT) or ventricular fibrillation (VF) detection and therapy parameters can reduce the combined incidence of device-delivered shocks, arrhythmic syncope, and untreated sustained symptomatic VT/VF... |
7,445 | [The impact of quality of cardiopulmonary resuscitation on post-resuscitation inflammatory reaction in a porcine cardiac arrest model]. | To evaluate the effects of quality of non-standard cardiopulmonary resuscitation (N-CPR) and new guidelines recommended standard CPR (S-CPR) on post-resuscitation inflammatory reaction in a cardiac arrest (CA) porcine model.</AbstractText>Eighteen pigs were randomly divided into two groups, and ventricular fibrillation... |
7,446 | Downregulated FKBP12.6 expression and upregulated endothelin signaling contribute to elevated diastolic calcium and arrhythmogenesis in rat cardiomyopathy produced by l-thyroxin. | Dissociation of FKBP12.6 from RyR2 is considered as an important molecular event resulting in calcium leak and an increased risk in arrhythmogenesis. We hypothesized that augmented ventricular fibrillation (VF) on reperfusion of rat cardiomyopathy induced by l-thyroxin may result from elevated diastolic Ca(2+) levels d... |
7,447 | Electrocardiographic features in a patient with the coexistence of long QT syndrome and coronary vasospasm. | A 20-year-old woman suffered from cardiopulmonary arrest due to ventricular fibrillation. The electrocardiogram after resuscitation showed prolonged QTc interval with bifid T wave. On the third hospital day, the QTc interval and the T-wave changes improved. However, the QTc interval was distinctively prolonged after ad... |
7,448 | Lack of diurnal variation of P-wave and QT dispersions in patients with heart failure. | P-wave dispersion (PWD) is a new parameter for the assessment of risk of atrial fibrillation and has been reported to be increased in heart failure. Diurnal variation of the PWD has been reported in patients with coronary artery disease (CAD). QT dispersion (QTD) has also a circadian variation. In this study we aimed t... |
7,449 | Effects of continuous and triggered atrial overdrive pacing on paroxysmal atrial fibrillation in pacemaker patients. | The aim of the study was to compare the effects of different pacing strategies to prevent paroxysmal atrial fibrillation (AF): triggered atrial overdrive pacing versus the combination of triggered and continuous overdrive pacing.</AbstractText>Patients with an indication for dual-chamber pacing (Selection 9000, Prevent... |
7,450 | Malignant arrhythmia in apical ballooning syndrome: risk factors and outcomes. | We sought to determine the frequency and outcomes with symptomatic arrhythmia in patients with apical ballooning syndrome (ABS).</AbstractText>A retrospective review of the Mayo Clinic Angiography database was conducted to identify patients who met the Mayo criteria for ABS. Patients with documented arrhythmias formed ... |
7,451 | Troponin elevation in patients with various tachycardias and normal epicardial coronaries. | Troponin elevation is usually synonymous with acute coronary syndrome (ACS). Although sensitive for ACS, the elevation of serum troponin, in the absence of clinical evidence of ischemia, should prompt a search for other etiologies of myocardial necrosis. In fact, elevated values of troponin are correlated with myocardi... |
7,452 | Nitric oxide inhibits Kv4.3 and human cardiac transient outward potassium current (Ito1). | Chronic atrial fibrillation (CAF) is characterized by a shortening of the plateau phase of the action potentials (AP) and a decrease in the bioavailability of nitric oxide (NO). In this study, we analysed the effects of NO on Kv4.3 (I(Kv4.3)) and on human transient outward K(+) (I(to1)) currents as well as the signalli... |
7,453 | Subsequent ventricular fibrillation and survival in out-of-hospital cardiac arrests presenting with PEA or asystole. | The prognostic implications of conversion to ventricular fibrillation (VF) in out-of-hospital cardiac arrest (OHCA) patients with an initial non-shockable rhythm are unclear.</AbstractText>Among OHCA patients with an initial non-shockable rhythm, survival is better in individuals who subsequently develop VF and are def... |
7,454 | Comparison of benefits and mortality in cardiac resynchronization therapy in patients with atrial fibrillation versus patients in sinus rhythm (Results of the Spanish Atrial Fibrillation and Resynchronization [SPARE] Study). | The efficacy of cardiac resynchronization therapy (CRT) in patients with atrial fibrillation (AF) and the need for atrioventricular junction ablation in these patients is controversial. The aim of the study was to analyze CRT results in patients with permanent AF. A total of 470 consecutive patients who underwent CRT i... |
7,455 | [Prophylactic use of cardiac implantable defibrillators in patients with severe left ventricular dysfunction: how to deal with decision making among guidelines, clinical practice, ethical problems, and limited economic resources]. | Sudden cardiac death (SCD) is usually due to ventricular tachycardia/fibrillation and represents one of the most important medical and socio-economical problems in western countries. It accounts for approximately 1 life/1000 subjects/year. New and effective treatments are necessary to reduce such dramatic event. During... |
7,456 | [Effects of pretreatment with amiodarone infusion in patients with persistent atrial fibrillation submitted to external electrical cardioversion: a single center experience]. | Several studies demonstrated the efficacy of amiodarone pretreatment in achieving bet-ter outcomes after electrical cardioversion of atrial fibrillation. In the majority of cases, oral amiodarone for at least 1 month was administered, with the result of lengthening of pre-cardioversion time. Only one study in the liter... |
7,457 | Virtual electrodes and the induction of fibrillation in Langendorff-perfused rabbit ventricles: the role of intracellular calcium. | A strong premature electrical stimulus (S(2)) induces both virtual anodes and virtual cathodes. The effects of virtual electrodes on intracellular Ca(2+) concentration ([Ca(2+)](i)) transients and ventricular fibrillation thresholds (VFTs) are unclear. We studied 16 isolated, Langendorff-perfused rabbit hearts with sim... |
7,458 | Inducibility of atrial fibrillation during electrophysiologic evaluation is associated with increased dispersion of atrial refractoriness. | The impact of atrial dispersion of refractoriness (Disp_A) in the inducibility and maintenance of atrial fibrillation (AF) has not been fully resolved.</AbstractText>To study the Disp_A and the vulnerability (A_Vuln) for the induction of self-limited (<60 s) and sustained episodes of AF.</AbstractText>Forty-seven pa... |
7,459 | QT prolongation is an unreliable predictor of ventricular arrhythmia. | Not all drugs that prolong the QT interval are proarrhythmic, and absence of QT prolongation is no guarantee for lack of proarrhythmia. Thus, QT prolongation is an unreliable predictor of ventricular arrhythmia. Development of drugs based on the absence of QT prolongation may stop development of some of the safest agen... |
7,460 | Transmural dispersion of refractoriness and conduction velocity is associated with heterogeneously reduced connexin43 in a rabbit model of heart failure. | Heterogeneity of repolarization and conduction is a potential source of arrhythmogenesis. In heart failure (HF), intercellular coupling is reduced and heterogeneities may become evident because of reduced intercellular coupling.</AbstractText>This study sought to investigate connexin43 (Cx43) expression, conduction vel... |
7,461 | Feasibility of endoscopic guidance for nonsurgical transthoracic atrial and ventricular epicardial ablation. | Epicardial catheter ablation via subxiphoid percutaneous access currently is used upon failure of endocardial catheter ablation. The safety, efficacy, and applicability of epicardial catheter ablation likely will improve with direct visualization of the pericardial space.</AbstractText>The purpose of this study was to ... |
7,462 | Future directions in cardiocerebral resuscitation. | Outcomes from pediatric cardiac arrest and cardiopulmonary resuscitation (CPR) seem to be incrementally improving. The past 2 decades have brought advances in the understanding of the pathophysiology of cardiac arrest and ventricular fibrillation, better treatment strategies, and a more robust standard for CPR epidemio... |
7,463 | Clinical importance of short-long-short sequences: analysing the mode of onset of ventricular tachycardias and atrial fibrillation. | Clinical importance of atrial and ventricular ectopic beats are investigated in some experimental and clinical trials. They are common and occur in a broad spectrum of the population. This includes patients without structural heart disease and those with any form of cardiac disease, independent of severity. Although we... |
7,464 | A focus on when and when not to use antiarrhythmic drugs in treating ventricular arrhythmias and indications for the use of automatic implantable cardioverter-defibrillators. | Underlying causes of ventricular tachycardia (VT) or complex ventricular arrhythmias (VA) should be treated if possible. Antiarrhythmic drugs should not be used to treat asymptomatic persons with complex VA and no heart disease. Beta blockers are the only antiarrhythmic drugs that have been demonstrated to reduce morta... |
7,465 | Functional status after operation for Ebstein anomaly: the Mayo Clinic experience. | The objective of this study was to review the long-term functional outcome of patients with Ebstein anomaly who had cardiac operation at our institution.</AbstractText>Ebstein anomaly is a spectrum of tricuspid valvular and right ventricular dysplasia. Many patients will require operation in an attempt to improve quali... |
7,466 | Atrial-selective sodium channel blockers: do they exist? | The risk of developing severe ventricular arrhythmias and/or organ toxicity by currently available drugs used to treat atrial fibrillation (AF) has prompted the development of atrial-selective antiarrhythmic agents. Until recently the principal focus has been on development of agents that selectively inhibit the ultra-... |
7,467 | Inward rectifier potassium currents as a target for atrial fibrillation therapy. | Subunits of inwardly rectifying potassium channels (Kir) are expressed in many different tissues of the human body. Inward rectifier currents expressed in the heart are constituted by pore-forming alpha-subunits of Kir2, Kir3, and Kir6 subfamilies. Characteristic properties of inward rectifiers comprise small outward c... |
7,468 | Electrocardiographic abnormalities in patients with acute burn injuries. | To determine the incidence and types of electrocardiographic (ECG) abnormalities in patients admitted with acute burn injuries and correlate them with the degree and the extent of burn injuries.</AbstractText>Retrospective analysis of 192 patients admitted to the burn unit was performed. Thirty-four patients met the in... |
7,469 | Outcome after implantation of cardioverter defibrillator [corrected] in patients with Brugada syndrome: a multicenter Israeli study (ISRABRU). | Many electrophysiologists recommend implantable cardioverter defibrillators for patients with Brugada syndrome who are cardiac arrest survivors or presumed at high risk of sudden death (patients with syncope or a familial history of sudden death or those with inducible ventricular fibrillation at electrophysiologic stu... |
7,470 | Oral anticoagulation in patients with cardiomyopathy or heart failure in sinus rhythm. | Despite many prospective randomized studies defining the benefits of anticoagulation in atrial fibrillation (AF), there have been no adequate studies in cardiomyopathy (CM) in sinus rhythm.</AbstractText>We review the current knowledge of the risk of stroke in CM, left ventricular systolic dysfunction and heart failure... |
7,471 | Radiofrequency ablation of drug-refractory atrial fibrillation: an observational study comparing 'ablate and pace' with pulmonary vein isolation. | To compare clinical characteristics, procedure complexity, acute and long-term outcome of 'ablate and pace' (A&P) with pulmonary vein isolation (PVI) in patients with drug-refractory atrial fibrillation (AF). So far, only few small studies have compared the two procedures.</AbstractText>We analysed retrospectively ... |
7,472 | Regional endocardial left atrial voltage and electrogram fractionation in patients with atrial fibrillation. | Heterogeneities in electrophysiological properties may contribute to the development of atrial fibrillation, and regional disparities in endocardial voltage in the left atrium have been related to arrhythmogenic mechanisms. This study aimed at investigating endocardial voltage in different regions of the left atrium in... |
7,473 | Diagnostic tools for atrial tachyarrhythmias in implantable pacemakers: a review of technical options and pitfalls. | Correct pacemaker (PM) diagnosis of paroxysmal atrial tachyarrhythmias is crucial for their prevention and intervention with specific atrial pacing programmes. The PM mode switch to only ventricular pacing after detection of atrial tachyarrhythmias is often used as the parameter to quantify the 'burden' of atrial tachy... |
7,474 | Off-pump coronary artery bypass in multi-vessel disease: effect of ejection fraction on early and midterm mortality and morbidity. | Left ventricular function is an independent predictor of operative mortality. The outcome of myocardial revascularization is greatly affected by the severity of impairment of cardiac function. The present study was undertaken to find the early and midterm mortality and morbidity among patients with different degrees of... |
7,475 | Early predictors of outcome in comatose survivors of ventricular fibrillation and non-ventricular fibrillation cardiac arrest treated with hypothermia: a prospective study. | Current indications for therapeutic hypothermia (TH) are restricted to comatose patients with cardiac arrest (CA) due to ventricular fibrillation (VF) and without circulatory shock. Additional studies are needed to evaluate the benefit of this treatment in more heterogeneous groups of patients, including those with non... |
7,476 | [Dynamic of the changes of the paced QT dispersion after ventricular pacemaker implantation (WIR) and radiofrequency atrioventricular junction ablation in drug refractory atrial fibrillation]. | Transcutaneous RF catheter ablation of the atrioventricular junction (AVJ) in pts with ventricular pacemaker (VVIR) implantated is an accepted treatment for drug-intolerant or drug refractory atrial fibrillation. The ventricular arrhythmias and sudden cardiac death may be associated with increased of QT dispersion (QTD... |
7,477 | Morphology discrimination in implantable cardioverter-defibrillators: consistency of template match percentage during atrial tachyarrhythmias at different heart rates. | Morphology discrimination (MD) in implantable cardioverter-defibrillators (ICDs) is based on the comparison of the ventricular electrogram during tachycardia with a stored reference template obtained during baseline rhythm. However, the effect of heart rate on the template match percentage during supraventricular tachy... |
7,478 | Prognostic value of short-deceleration time of mitral inflow E velocity: implications in patients with atrial fibrillation and left-ventricular systolic dysfunction. | The aim of this prospective study was to evaluate the contribution of an initially shortened deceleration time of mitral inflow E velocity (E-wave DT) to predict survival in patients with left-ventricular (LV) systolic dysfunction in atrial fibrillation (AF) and in sinus rhythm (SR).</AbstractText>To date, few data are... |
7,479 | Localized left atrial administration of tPA for the treatment of mechanical mitral valve thrombosis. | Prosthetic valve thrombosis is a dangerous and unfortunately not uncommon medical situation, often seen as a medical emergency. Patients with previously unseen and more confounding medical problems are presenting, making the decision regarding therapeutic options even more complicated. In this case report, we describe ... |
7,480 | Angiographic and clinical manifestations of coronary fistulas in Chinese people: 15-year experience. | Coronary artery fistula (CAF) is an anomaly resulting in the steal phenomenon of coronary blood flow, which may cause morbidity or mortality. CAFs in Chinese patients after long-term follow-up of 15 years were retrospectively analyzed.</AbstractText>From September, 1992 to August, 2007, 152 CAFs were detected in 28,210... |
7,481 | Role of potassium currents in cardiac arrhythmias. | Abnormal excitability of myocardial cells may give rise to ectopic beats and initiate re-entry around an anatomical or functional obstacle. As K(+) currents control the repolarization process of the cardiac action potential (AP), the K(+) channel function determines membrane potential and refractoriness of the myocardi... |
7,482 | Episodic syncope in hypertrophic cardiomyopathy: evidence for inappropriate vasodilation. | Symptoms of impaired consciousness (syncope and pre-syncope) occur in 15-25% of patients with hypertrophic cardiomyopathy (HCM).1 In young patients a history of recurrent syncope is associated with an increased risk of sudden death.2(-)5 Syncope usually occurs without warning or symptoms suggestive of the cause. Detail... |
7,483 | Spatial-temporal filter effect in a computer model study of ventricular fibrillation. | Prediction of countershock success from ventricular fibrillation (VF) ECG is a major challenge in critical care medicine. Recent findings indicate that stable, high frequency mother rotors are one possible mechanism maintaining VF. A computer model study was performed to investigate how epicardiac sources are reflected... |
7,484 | [Cardioprotective, inotropic, and anti-arrhythmia properties of a complex adaptogen "Tonizid"]. | We have studied the new complex plant adaptogen preparation tonizid containing dry extracts of Aralia mandshurica, Panax ginseng, Rhodiola rosea, and Eleutherococcus senticosus. The course administration (5 days) of tonizid led to a decrease in the ratio of necrotic zone size/risk area during a 45-min local ischemia an... |
7,485 | Comparison of outcomes in patients undergoing defibrillation threshold testing at the time of implantable cardioverter-defibrillator implantation versus no defibrillation threshold testing. | Inability to perform defibrillation threshold (DFT) testing during implantable cardioverter defibrillator (ICD) implantation due to co-morbidities may influence long-term survival.</AbstractText>Retrospective review at The University of Michigan (1999-2004) identified 55 patients undergoing ICD implantation without DFT... |
7,486 | Is the combination therapy of IKr-channel blocker and left stellate ganglion block effective for intractable ventricular arrhythmia in a cardiopulmonary arrest patient? | We have previously reported that the defibrillation success rate of intravenous nifekalant hydrochloride (NIF), a pure IKr-channel (IKr: the rapid components of the delayed rectifier potassium current) blocker, was more than 75% for lidocaine-resistant ventricular tachycardia and fibrillation (VT/VF) in patients with o... |
7,487 | Dual-site right ventricular pacing. A rescue alternative in cardiac resynchronisation therapy implantation failure? More efficient stimulation for patients with borderline cardiac resynchronisation therapy indication? Less harmful ventricular pacing? | Permanent cardiac pacing is nowadays a widespread method for the cure of conduction system diseases, improving quality of life and often saving patients' lives. In the twentieth century, scientific efforts were focused on extending battery life, improving sensitivity and reliability, minimizing the dimensions of the de... |
7,488 | Repeated ventricular. | Few publications report the possibility of "torsade de pointes"" (TdP) type tachycardia and ventricular fibrillation occurring in patients with prolonged QT syndrome in the course of hypothyroidism. The authors present the case of a 51-year-old woman with Hashimoto disease and hypothyroidism, inadequately supplemented ... |
7,489 | The management of Brugada syndrome patients. | Brugada syndrome is a congenital electrical disorder characterised by the appearance of distinctive QRST-T patterns in the right precordial leads and an increased risk of sudden death (SCD) in young healthy adults. Although chamber enlargement is not apparent in most cases, autopsy and histological investigations have ... |
7,490 | Lightning-induced ventricular fibrillation. | We present a case of a previously healthy 17 year-old white male boy scout who collapsed after a lightning strike, and was found to be in ventricular fibrillation when emergency medical services arrived. The ventricular fibrillation was defibrillated into sinus rhythm after a single direct current (DC) countershock. Ho... |
7,491 | Telecardiology applied to a region-wide public emergency health-care service. | To assess feasibility and reliability of telecardiology technologies applied to a region-wide public emergency health-care service.</AbstractText>About 27,841 patients from all over Apulia (19.362 km(2), 4 million inhabitants) were referred from October 2004 until April 2006 to public emergency health-care number "118"... |
7,492 | The effects of dietary hempseed on cardiac ischemia/reperfusion injury in hypercholesterolemic rabbits. | Hempseed is a novel functional food that contains several health-promoting polyunsaturated fatty acids (PUFAs). PUFAs, such as those found in flaxseed and fish, have been shown to protect the heart against arrhythmias following ischemia/reperfusion.</AbstractText>TO INVESTIGATE THE POTENTIAL OF DIETARY HEMPSEED AS A CA... |
7,493 | Atrial conduction delay and its association with left atrial dimension, left atrial pressure and left ventricular diastolic dysfunction in patients at risk of atrial fibrillation. | Atrial conduction delay and its association with left atrial dimension, left atrial pressure and left ventricular (LV) diastolic dysfunction in patients at risk of atrial fibrillation (AF) may be assessed by high-resolution electrocardiography of P wave.</AbstractText>To determine how left atrial size, left atrial pres... |
7,494 | Remodelling of cardiac gap junction connexin 43 and arrhythmogenesis. | In cardiac muscle, the gap junction plays a pivotal role in electrical cell-to-cell coupling and impulse propagation between cells. The function of the gap junction depends on the regulation of connexin in the gap junction channel. A dysfunction of the gap junction is possibly caused by the downregulation of connexin o... |
7,495 | Moderate physical exercise: a simplified approach for ventricular rate control in older patients with atrial fibrillation. | This prospective pilot-study was performed to assess whether regular moderate physical activity elevates the parasympathetic tone to the atrio-ventricular node and decreases VR during permanent AF.</AbstractText>Adequate ventricular rate (VR) control in patients with permanent atrial fibrillation (AF) is not easy to ac... |
7,496 | Antithrombotic therapy in atrial fibrillation: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). | This chapter about antithrombotic therapy in atrial fibrillation (AF) is part of the American College of Chest Physicians Evidence-Based Guidelines Clinical Practice Guidelines (8th Edition). Grade 1 recommendations indicate that most patients would make the same choice and Grade 2 suggests that individual patient's va... |
7,497 | Chronic carbon monoxide exposure increases electrocardiographic P-wave and QT dispersion. | We investigated the association between chronic carbon monoxide (CO) exposure and electrocardiographic maximum/minimum P-wave duration (Pmax/Pmin), P-wave dispersion (Pd), maximum/minimum QT interval (QTmax/QTmin), and QT and corrected QT dispersion (QTd/cQTd), which are known as predictors of atrial fibrillation, vent... |
7,498 | Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion. | Ventricular arrhythmias are life-threatening complications of heart failure and myocardial ischemia. Increased diastolic Ca2+ overload occurring in ischemia leads to afterdepolarizations and aftercontractions that are responsible for cellular electric instability. We inquired whether sarcoplasmic reticulum Ca2+ ATPase ... |
7,499 | Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent. | The aim of this study was to verify whether exaggerated arrhythmogenesis is attributed to inflammatory factors actively involving an excess of reactive oxygen species (ROS), transforming growth factor (TGF)-beta and endothelin (ET). We hypothesized that CPU86017, derived from berberine, which possesses multi-channel bl... |
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