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7,500
Elevated temporal lability of myocardial repolarization after coronary artery bypass grafting.
Ventricular arrhythmias are uncommon after coronary artery bypass grafting (CABG), but the incidence and mortality are high in certain subsets of patients during the early recovery after surgery. Elevated temporal lability of myocardial repolarization has been associated with sudden cardiac death. The aim of the curren...
7,501
Aldosterone synthase gene polymorphism as a determinant of atrial fibrillation in patients with heart failure.
We analyzed the possible association between aldosterone synthase (CYP11B2) T-344C polymorphism, which is associated with increased aldosterone activity, and the prevalence of atrial fibrillation (AF) in 196 consecutive patients who had symptomatic systolic heart failure (HF; left ventricular ejection fraction <40%)...
7,502
Case ascertainment and estimated incidence of drug-induced long-QT syndrome: study in Southwest France.
The aim of this study was to investigate the incidence and reporting rate of drug-induced long-QT syndrome (LQTS) in France [defined by evidence of torsades de pointes (TdP), QT prolongation and exposure to a relevant drug] and to assess feasibility of case collection for drug-induced LQTS.</AbstractText>A retrospectiv...
7,503
Risk of atrial fibrillation in dipper and nondipper sustained hypertensive patients.
The risk of atrial fibrillation (AF) in sustained hypertensive patients with different circadian blood pressure (BP) patterns is unknown. We investigated the risk of new onset AF in dipper and nondipper sustained hypertensive patients.</AbstractText>The occurrence of AF was evaluated in 1141 patients aged &gt; or = 40 ...
7,504
Attitudes toward automated external defibrillator use in Japan.
The American Heart Association 2005 Guidelines recommend immediate defibrillation for ventricular fibrillation (VF) of short duration, such as witnessed sudden cardiac arrest. However, it is unclear if public-access automated external defibrillators (AEDs) would actually be used in Japan, because there have been few st...
7,505
[Left ventricular systolic function, paced QT dispersion, exercise tolerance and quality of life in long term follow up after ventricular pacemaker implantation (VVIR) and radiofrequency atrioventricular junction ablation in drug refractory atrial fibrillation].
THE AIM OF THE STUDY was to analyze left ventricular systolic function and dimensions, paced QT dispersion (QTD), exercise tolerance (six minute walk test- M6) and quality of life (QOL) after RFAVJ in a 6-month (6m) and a 24-month (24m) follow-up.</AbstractText>RFAVJ was performed in 30 pts (18 men and 12 women) aged f...
7,506
Atrial fibrillation in heart failure: the chicken or the egg?
Atrial fibrillation (AF) and heart failure (HF) are the emerging epidemics of cardiovascular disease in the new millennium. Both are responsible for considerable morbidity and mortality and health budget expenditure. The advent of catheter ablation for patients with AF has provided important new insights into the relat...
7,507
Endocardial transcatheter stimulation of the AV nodal fat pad: stabilization of rapid ventricular rate response during atrial fibrillation in left ventricular failure.
Recent acute studies demonstrated that atrioventricular (AV) node vagal stimulation during atrial fibrillation (AF) decreases the mean ventricular rate, thus improving hemodynamics.</AbstractText>We report a case of a woman with acute heart failure (HF), chronic AF with untreatable ventricular rapid response, in severe...
7,508
[ECG changes in alcoholic intoxication].
Patients with acute alcohol intoxication often present with pathological electrocardiographic (ECG) changes. The changes are more frequent and prognostically more significant in chronic alcoholics, in patients with ischaemic heart disease (IHD), in alcohol cardiomyopathy or another organic heart disease, but they can a...
7,509
[Therapy of acute myocardial infarction in the prehospital setting].
The time period from symptom onset to hospital admission is of outstanding importance for the prognosis of a patient with an acute myocardial infarction. He is threatened by sudden cardiac death triggered by ventricular fibrillation on the one hand and on the other hand this period offers the chance for a timely decisi...
7,510
Angiotensin II receptor blockers and cardiovascular protection: focus on left ventricular hypertrophy regression and atrial fibrillation prevention.
Left ventricular hypertrophy (LVH) and atrial fibrillation (AF) are strong predictors of cardiovascular (CV) morbidity and mortality, independently of blood pressure levels and other modifiable and nonmodifiable risk factors. The actions of circulating and tissue angiotensin II, mediated by AT1 receptors, play an impor...
7,511
Biatrial anatomical reverse remodelling after radiofrequency catheter ablation for atrial fibrillation: evidence from real-time three-dimensional echocardiography.
Reports using two-dimensional echocardiography have indicated that radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) results in a reduction in the left atrial (LA) size. Furthermore, the effect of pulmonary vein isolation (PVI) on right atrial (RA) anatomical remodelling has not been studied. Three-d...
7,512
Atrial Fibrillation and Heart Failure.
Atrial fibrillation is common in heart failure patients and is associated with increased mortality. Pharmacologic trials have not shown any survival benefit for a rhythm control over a rate control strategy. It has been suggested that sinus rhythm is associated with a survival benefit, but that the risks of anti-arrhyt...
7,513
Unoperated tetralogy of Fallot in a 68-year-old patient.
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease, generally treated with total correction within the first two years of life. Occasionally, some unoperated cases can reach older ages. A 68-year-old woman with diabetes mellitus presented with swelling in legs and abdomen, weakness, exertion...
7,514
Evidence for benefits of angiotensin receptor blockade beyond blood pressure control.
Elevated levels of angiotensin II result in oxidative stress and endothelial dysfunction, which initiate atherogenic pathologic processes that are important in cardiovascular disease development. Angiotensin II induces its deleterious effects primarily through the type 1 receptor; these effects are inhibited by angiote...
7,515
Thyroid hormones suppress epsilon-PKC signalling, down-regulate connexin-43 and increase lethal arrhythmia susceptibility in non-diabetic and diabetic rat hearts.
We examined whether thyroid hormones affect myocardial epsilon-PKC signalling, downstream target substrate, connexin-43 (Cx43) and arrhythmogenesis in non-diabetic and diabetic rats. Diabetes was induced by a single streptozotocin injection (50mg/kg, i.v.). Triiodothyronine (T(3)) was applied by gavage (1microg/kg of b...
7,516
Aborted sudden death from sustained ventricular fibrillation.
Ventricular fibrillation usually is sustained and unrelenting in human subjects and rarely is self-terminating after 30 seconds' duration. Temporal evolution of the arrhythmia in our patient suggested that organization of electrical activity varies over time. Interaction of organization with high catecholamine levels a...
7,517
A high peak current 150-J fixed-energy defibrillation protocol treats recurrent ventricular fibrillation (VF) as effectively as initial VF.
We tested the hypothesis that the frequency of shock success differs between initial and recurrent episodes of ventricular fibrillation (VF).</AbstractText>Out-of-hospital cardiac arrest patients presenting with VF from December 1996 to February 2007 defibrillated using an AED with a fixed-energy protocol (150 J) (Phil...
7,518
Palpitations in athletes.
In an athletic population, the incidence of palpitations varies from 0.3% to as high as 70%, depending on age and type of sport being studied. Palpitations, or an awareness of an increased or abnormal heart beat, are rare in the school-age athlete, but much more common in older endurance athletes. The majority are felt...
7,519
Delayed protective effects of hyperoxia against cardiac arrhythmias and infarction in anesthetized rats.
Previous studies have shown that pretreatment with normobaric hyperoxia has cardioprotective effect in isolated rat heart. The present study was designed to test the hypothesis that pretreatment normobaric hyperoxia could induce delayed cardioprotection effect in an in vivo regional heart ischemia.</AbstractText>Experi...
7,520
Impact of pre-existing conditions, age and the length of cardiopulmonary bypass on postoperative outcome after repair of the ascending aorta and aortic arch for aortic aneurysms and dissections.
Repair of the ascending aorta and aortic arch carries a high morbidity and mortality, which can be complicated by the often emergent nature of the intervention.</AbstractText>We retrospectively evaluated the morbidity, mortality, and long-term survival in 101 patients who underwent repair of ascending aorta and aortic ...
7,521
Short-long-short sequence caused by ventricular safety pacing inducing ventricular tachycardia in a patient with a dual-chamber implantable cardioverter defibrillator.
Ventricular safety pacing (VSP) is an algorithm used to prevent crosstalk inhibition and ventricular capture during the vulnerable period. We report a 78-year-old man with implantable dual-chamber defibrillator, in whom clusters of ventricular tachycardias (VTs) were provoked by the VSP. During rapid DDDR pacing, the d...
7,522
The impact of prehospital transport interval on survival in out-of-hospital cardiac arrest: implications for regionalization of post-resuscitation care.
There is growing evidence that therapeutic hypothermia and other post-resuscitation care improves outcomes in out-of-hospital cardiac arrest (OHCA). Thus, transporting patients with return of spontaneous circulation (ROSC) to specialized facilities may increase survival rates. However, it is unknown whether prolonging ...
7,523
Emergency laparoscopic surgery for complicated diverticular disease.
The aim of this study was to analyse the outcome of emergency laparoscopic surgical management of complicated diverticular disease.</AbstractText>A prospectively collected electronic database of all colorectal laparoscopic procedures between April 2001 and September 2007 has been used to identify outcomes in patients p...
7,524
Use of a standardized order set for achieving target temperature in the implementation of therapeutic hypothermia after cardiac arrest: a feasibility study.
Induced hypothermia (HT) after cardiac arrest improved outcomes in randomized trials. Current post-cardiac arrest treatment guidelines advocate HT; however, utilization in practice remains low. One reported barrier to adoption is clinician concern over potential technical difficulty of HT. We hypothesized that using a ...
7,525
Iatrogenic circumflex coronary lesion in mitral valve surgery: case report and review of the literature.
Ischemic iatrogenic lesions can complicate surgical procedures on the mitral valve. One of the causative mechanisms is direct injury to or distortion of the circumflex coronary artery. The risk of damaging the circumflex coronary artery depends mainly upon the proximity of that vessel to the posterior segment of the mi...
7,526
Transvenous right ventricular pacing in a patient with tricuspid mechanical prosthesis.
We report a patient in whom permanent endocardial pacing was accomplished by passage of the electrode through a mechanical tricuspid valve. Echocardiography study showed a minimal tricuspid regurgitation.
7,527
Long-term follow-up of Tako-Tsubo-like syndrome: a retrospective study of 22 cases.
To assess the late outcome of the Tako-Tsubo like syndrome in a community hospital in northern Italy.</AbstractText>We reviewed 2233 patients who were admitted from 2001 to 2006 with diagnosis of acute coronary syndrome. Twenty-two patients (1%) presenting clinical and instrumental characteristics of Tako-Tsubo like sy...
7,528
Fatal QT interval.
A 21-year-old woman, without medical history, was admitted after cardiac arrest. Cardiopulmonary resuscitation and use of semiautomatic defibrillator quickly restored sinus rhythm. Clinical examination was normal with no cardiac murmur or abnormal heart sound. Electrocardiogram revealed sinus rhythm with short QT inter...
7,529
Cardiac arrest in the setting of diet pill consumption.
The obesity epidemic currently plaguing the United States has spurred the development of a vast number of drugs to assist in the battle against obesity and its associated complications. The need to loose weight often causes patients to loose sight of or even ignore the serious side effects of some of the most widely us...
7,530
Bystander cardiopulmonary resuscitation for out-of-hospital cardiac arrest in the Hispanic vs the non-Hispanic populations.
The aim of this study is to compare rates of bystander cardiopulmonary resuscitation (CPR) for Hispanic and non-Hispanic out-of-hospital cardiac arrest (OOHCA) victims in Arizona.</AbstractText>This is a secondary analysis of consecutive OOHCA victims prospectively enrolled into our statewide OOHCA quality improvement ...
7,531
Acute myocardial infarction with angiographically normal coronary arteries.
The authors present the case of a 51-year-old woman, with no known cardiovascular risk factors, admitted with anterior acute myocardial infarction complicated by primary ventricular fibrillation, who underwent reperfusion therapy with tenecteplase. Left heart catheterization on the sixth day showed left ventricular ant...
7,532
A fatal case of oleandrin poisoning.
The study presents a case of fatal poisoning with oleander leaves in an adult diabetic male. After repeated vomiting, and gastrointestinal distress the patient was admitted at the hospital with cardiac symptoms 1h after the ingestion. Urine samples were assayed immunochemically and by GC-MS for drugs of abuse and for g...
7,533
Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel.
Brugada syndrome has been linked to mutations in SCN5A. Agents that dissociate slowly from the sodium channel such as flecainide and ajmaline unmask the Brugada syndrome electrocardiogram and precipitate ventricular tachycardia/fibrillation. Lidocaine, an agent with rapid dissociation kinetics, has previously been show...
7,534
Acute and long-term efficacy and safety of catheter cryoablation of the cavotricuspid isthmus for treatment of type 1 atrial flutter.
Atrial flutter (AFL) is commonly treated by radiofrequency catheter ablation. Catheter-based cryoablation may be an effective alternative with potential advantages.</AbstractText>The purpose of this study was to study the acute and long-term safety and efficacy of catheter-based cryoablation for treatment of cavotricus...
7,535
One-stage correction of aortic coarctation and severe mitral regurgitation via left posteriolateral thoracotomy in a 2-year-old child.
We successfully treated a case of a 2-year-old male with aortic coarctation coexisting with severe mitral regurgitation via left posteriolateral thoracotomy at one stage. After a mitral valve replacement under perfused ventricular fibrillation with moderate hypothermia, we repaired the aortic coarctation with coarctati...
7,536
Atrial fibrillation due to late amiodarone-induced thyrotoxicosis.
A 60-year-old male patient complaining of palpitations, fatigue, weakness and weight loss of 1 month's duration was hospitalized in our cardiology department for atrial fibrillation. Thyroid function test results were compatible with thyrotoxicosis. The patient had been taking amiodarone for 2.5 years for hypertrophic ...
7,537
Logarithm of the absolute correlations of the ECG waveform estimates duration of ventricular fibrillation and predicts successful defibrillation.
Measures of the ventricular fibrillation (VF) waveform may enable better allocation of cardiac arrest treatment by discriminating which patients should receive immediate defibrillation versus alternate therapies such as CPR. We derive a new measure based on the 'roughness' of the VF waveform, the Logarithm of the Absol...
7,538
Biphasic external defibrillation for adults in ventricular fibrillation or pulseless ventricular tachycardia.
Cardiac arrest, as a result of ventricular fibrillation or pulseless ventricular tachycardia, is a common phenomenon, and the only treatment available is defibrillation. Currently, defibrillators deliver either a monophasic or biphasic shock, depending on the device used. In 2005, the American Heart Association publish...
7,539
Obstructive sleep apnea and cardiovascular disease: role of the metabolic syndrome and its components.
Although obstructive sleep apnea and cardiovascular disease have common risk factors, epidemiologic studies show that sleep apnea increases risks for cardiovascular disease independently of individuals' demographic characteristics (i.e., age, sex, and race) or risk markers (i.e., smoking, alcohol, obesity, diabetes, dy...
7,540
Hypersensitivity to administered adrenaline in tetraplegia.
Case report.</AbstractText>To describe two clinical examples of denervation hypersensitivity, an enhanced response to catecholamines demonstrated experimentally in tetraplegic patients.</AbstractText>USA.</AbstractText>A 63-year-old man with chronic paralysis at C4 ASIA Impairment Scale (AIS) A with partial preservatio...
7,541
Aspirated air in the pericardial space during epicardial catheterization may elevate the defibrillation threshold.
A 79-year-old woman without structural heart disease underwent catheter ablation of ventricular tachycardia. Successful ablation was achieved on the left ventricular epicardium using an epicardial approach via pericardial puncture. Thereafter, programmed stimulation induced ventricular fibrillation (VF). A 360 J biphas...
7,542
Comparison of a 10-breaths-per-minute versus a 2-breaths-per-minute strategy during cardiopulmonary resuscitation in a porcine model of cardiac arrest.
Hyperventilation during cardiopulmonary resuscitation (CPR) is harmful.</AbstractText>We tested the hypotheses that, during CPR, 2 breaths/min would result in higher cerebral perfusion pressure and brain-tissue oxygen tension than 10 breaths/min, and an impedance threshold device (known to increase circulation) would f...
7,543
Chronic ischemic mitral regurgitation induced in pigs by catheter-based coronary artery occlusion.
Ischemic mitral regurgitation (IMR) appears in 20-50% of patients after acute myocardial infarction, and entails an increased long-term mortality. In order to compensate for the diversified pathology in humans, this disease entity has been developed in pigs in order to allow investigations of therapeutic options agains...
7,544
Initial management of cardiac arrhythmias.
Diagnosis of acute arrhythmias requires recognition and interpretation of important electrocardiogram (ECG) findings, and knowledge of Australian resuscitation guidelines.</AbstractText>This article aims to provide a guide for general practitioners in managing patients who present with acute arrhythmias in the rural or...
7,545
Atrioventricular nodal ablation and biventricular pacing therapy with coronary venoplasty for severe heart failure with drug refractory atrial tachycardia.
A 53-year-old man was admitted to our hospital for dyspnea, associated with atrial tachycardia. He underwent mitral valve replacement and Maze operation for mitral regurgitation and atrial fibrillation and since then he suffered from drug refractory atrial tachycardia followed by cardiogenic shock with systolic heart f...
7,546
Rhode Islanders' attitudes towards the development of a statewide genetic biobank.
To explore the attitudes of a voluntary subset of Rhode Island residents towards the potential development of a large, prospective, population-based study of sudden cardiac arrest, which will include a biobank to store blood for future biochemical and molecular analyses.</AbstractText>A mailed survey and focus groups.<...
7,547
[How to treat arrhythmias in thoracic surgery].
After major noncardiac thoracic operations, various types of arrhythmia would occur. Particularly atrial fibrillation (Af), have remained one of the most frequent complications. In the literatures, risk factors for post operative Af have identified age, male, extent of pulmonary resection and mediastinal lymph node dis...
7,548
Genetics of congenital long QT syndrome and Brugada syndrome.
The inherited cardiac arrhythmias including congenital and acquired long QT syndrome (LQTS), Brugada syndrome, progressive cardiac conduction defect, catecholaminergic polymorphic ventricular tachycardia, arrhythmogenic right ventricular cardiomyopathy, familial atrial fibrillation, familial sick sinus syndrome and sho...
7,549
Thrombus detection by echocardiography in patients with acute ischemic stroke and chronic or new-onset atrial fibrillation.
Recent articles have promoted anticoagulation for potential sources of embolism detected on echocardiography, despite lack of data regarding risk/benefit ratio for anticoagulating many of these abnormalities. Conversely, we have found echocardiography use in ambulatory stroke care to be of low yield. However, direct vi...
7,550
[Amiodarone--still a useful antiarrhythmic drug].
In former days, amiodarone was mainly used as high-dose prescription for serious ventricular arrhythmias. The indication was life-saving and a high incidence of adverse effects was consequently accepted. Such patients are currently protected by an implantable cardioconverter-defibrillator (ICD), and the typical amiodar...
7,551
Chemical ablation of the Purkinje system causes early termination and activation rate slowing of long-duration ventricular fibrillation in dogs.
Endocardial mapping has suggested that Purkinje fibers may play a role in the maintenance of long-duration ventricular fibrillation (LDVF). To determine the influence of Purkinje fibers on LDVF, we chemically ablated the Purkinje system with Lugol solution and recorded endocardial and transmural activation during LDVF....
7,552
Minimal invasive mitral valve repair for mitral regurgitation: results of 1339 consecutive patients.
Some have expressed concern that minimal invasive mitral valve (MV) repair may not meet the standard of open surgical techniques. We therefore reviewed our results for minimal invasive MV repair for mitral regurgitation (MR).</AbstractText>Between March 1999 and February 2007, a total of 1536 consecutive patients under...
7,553
Impact of different compression-ventilation ratios during basic life support cardiopulmonary resuscitation.
The 2005 revised guidelines for cardiopulmonary resuscitation (CPR) suggest a universal compression-to-ventilation (C:V) ratio of 30:2. The effects of this ratio in a realistic CPR scenario have not been investigated completely.</AbstractText>After 4 min of untreated ventricular fibrillation (VF), 24 pigs were randomly...
7,554
Support vector machine-based arrhythmia classification using reduced features of heart rate variability signal.
This paper presents an effective cardiac arrhythmia classification algorithm using the heart rate variability (HRV) signal. The proposed algorithm is based on the generalized discriminant analysis (GDA) feature reduction scheme and the support vector machine (SVM) classifier.</AbstractText>Initially 15 different featur...
7,555
Relationship between amiodarone-induced subclinical lung toxicity and Th1/Th2 balance.
Although amiodarone is a potent antiarrhythmic agent, its clinical use is limited by serious lung toxicity. This study investigated the mechanisms of amiodarone-induced lung toxicity from an immunological perspective. Because interferon gamma (IFN-gamma: Th1 cytokine) inhibits pulmonary fibroblast proliferation whereas...
7,556
Delayed anti-arrhythmic effect of nitroglycerin in anesthetized rats: involvement of CGRP, PKC and mK ATP channels.
Delayed anti-infarct and anti-stunning effects of nitroglycerin (NTG) have well been established in some animal models. The main goals of this study in anesthetized rats were to determine whether NTG has a delayed anti-arrhythmic effect and if so, whether calcitonin gene-related peptide (CGRP), protein kinase C (PKC) a...
7,557
Establishing Arizona's statewide cardiac arrest reporting and educational network.
Only a few large cities have published their out-of-hospital cardiac arrest (OHCA) survival statistics using the Utstein style reporting method. To date, to the best of our knowledge there has been no published OHCA survival data for a state.</AbstractText>To describe the process, benefits, and challenges of establishi...
7,558
The effect of adenosine A1 receptor antagonism on return of spontaneous circulation and short-term survival in prolonged ventricular fibrillation.
Endogenous adenosine (ADO) is cardioprotective during ischemia and its myocardial concentration increases during untreated ventricular fibrillation (VF). We have previously shown that ADO A1 receptor (ADOA1R) antagonism hastens the time-dependent decay in VF waveform morphology during the circulatory phase of cardiac a...
7,559
Derivation of clinical predictors of failed rescue shock during out-of-hospital ventricular fibrillation.
Failed rescue shocks have been shown to decrease the likelihood of survival in the treatment of out-of-hospital ventricular fibrillation (VF). Avoidance of failed shocks may improve survival.</AbstractText>We sought to derive clinical predictors that could be used by emergency medical services (EMS) personnel to identi...
7,560
Delay prior to calling 9-1-1 is associated with increased mortality after out-of-hospital cardiac arrest.
We sought to characterize the collapse-to-9-1-1 call interval, to evaluate the frequency of pre-9-1-1 delay, and to assess whether delay is associated with decreased survival after out-of-hospital cardiac arrest (OHCA).</AbstractText>This was a five-year prospective survey of bystanders to adult OHCA cases in which the...
7,561
Long-term follow-up of patients with relatively high effective defibrillation threshold during cardioverter defibrillator implantation with endocardial leads.
We evaluated the 15-year outcome of patients with an implantable cardioverter defibrillator (ICD) and a relatively high defibrillation threshold (DFT).</AbstractText>After ICD implantation, patients were allocated to 3 groups: DFT 24-25 J (16 patients), effective defibrillation with 18-20 J (20 patients) and DFT &lt;15...
7,562
How much lung ventilation is obtained with only chest-compression CPR?
The objective of this 14-pig study was designed to determine the amount of lung ventilation obtainable by only rhythmic chest compression (100/min, 100 lbs). Tidal volume (TV), dead space (DS), and respiration rate (R) were measured with normal breathing and with rhythmic chest compression during ventricular fibrillati...
7,563
Elective and emergency defibrillation.
Defibrillation is the only effective treatment in cardiac arrest for ventricular fibrillation and pulseless ventricular tachycardia. This article aims to identify the need for defibrillation, both elective and emergency, and assist the nurse in understanding the evidence related to effective defibrillation (Nolan et al...
7,564
Both Purkinje cells and left ventricular posteroseptal reentry contribute to the maintenance of ventricular fibrillation in open-chest dogs and swine: effects of catheter ablation and the ventricular cut-and-sew operation.
Radiofrequency catheter ablation (RFCA) targeting the left ventricular posteroseptum (LVPS) and posterior papillary muscle (PPM) terminates or prevents ventricular fibrillation (VF) in rabbit and dog hearts. However, whether the mechanism of VF maintenance is reentry or focal Purkinje firing is unclear.</AbstractText>I...
7,565
Circulating adiponectin levels in patients with atrial fibrillation.
Atrial fibrillation (AF) characterized by atrial remodeling occurs with obesity-related conditions. Adiponectin, an adipose tissue-derived hormone exerts beneficial effects on ventricular remodeling, so in the present study the potential association between circulating adiponectin levels and atrial remodeling in patien...
7,566
ECG-edit function in multidetector-row computed tomography coronary arteriography for patients with arrhythmias.
ECG-gating is necessary for cardiac computed tomography, but is not suitable for arrhythmias, so the aim of this study was to evaluate the usefulness of the ECG-edit function for this purpose.</AbstractText>Of 1,221 patients undergoing 64-row multidetector-row computed tomography coronary angiography (coronary MDCT), 1...
7,567
Differences in ventricular vulnerability, serum enzyme activities, and electrolyte levels between male and female broilers.
Sudden death syndrome (SDS) is one of the most serious diseases of fast-growing broilers. The incidence of SDS may result from a decrease in ventricular function. The purpose of this study was to explore the mechanism of sexual difference in the sensitivity of broilers to SDS by measuring their ventricular vulnerabilit...
7,568
Prognostic value and temporal behavior of the planar QRS-T angle in patients with nonischemic cardiomyopathy.
The planar QRS-T angle can be easily obtained from standard 12-lead ECGs, but its predictive ability is not established. We sought to determine the predictive ability of the planar QRS-T angle in patients with nonischemic cardiomyopathy and to assess QRS-T angle behavior over time.</AbstractText>Baseline QRS-T angles f...
7,569
Survival rate and factors associated with 1-month survival of witnessed out-of-hospital cardiac arrest of cardiac origin with ventricular fibrillation and pulseless ventricular tachycardia: the Utstein Osaka project.
We reassessed 1-month survival of patients with witnessed out-of-hospital cardiac arrest (OHCA) of cardiac origin with ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT) in Osaka, Japan, and identified factors associated with 1-month survival using updated data from 1998 to 2004 collected based on ...
7,570
Post-resuscitation hemodynamics and relationship to the duration of ventricular fibrillation.
We have observed consistent hemodynamic patterns after restoration of spontaneous circulation (ROSC) after ventricular fibrillation (VF) cardiac arrest. We sought to characterize the time-course of these patterns, and to determine whether these differed based on duration of the VF insult.</AbstractText>We performed a r...
7,571
Drug-induced long QT syndrome in women: review of current evidence and remaining gaps.
Women are at an increased risk of drug-induced long QT syndrome (LQTS). This major cardiac adverse effect may lead to malignant polymorphic ventricular tachycardias, termed torsades de pointes, which may degenerate into ventricular fibrillation and cause sudden death.</AbstractText>This article reviews current evidence...
7,572
Age at repair affects the very long-term outcome of sinus venosus defect.
Records of patients who had repair of sinus venosus defect (SVD) between 1970 and 2008 were reviewed to predict very long-term outcome.</AbstractText>Repairs occurred in 104 consecutive patients (51 men), aged 29 +/- 23 years (range, 1 to 70 years). Seven had isolated SVD and 97 had associated lesions that required con...
7,573
Restoration of sinus rhythm by the Maze procedure halts progression of tricuspid regurgitation after mitral surgery.
Tricuspid regurgitation (TR) is common in patients undergoing mitral valve surgery, and atrial fibrillation (AF) can cause progression of TR. This study examined the hypothesis that correction of AF with the Maze procedure can prevent the late progression of TR after mitral valve surgery.</AbstractText>We compared seve...
7,574
Usefulness of left atrial volume index to predict heart failure hospitalization and mortality in ambulatory patients with coronary heart disease and comparison to left ventricular ejection fraction (from the Heart and Soul Study).
The predictive value of left atrial (LA) dilatation in ambulatory adults with coronary artery disease is not known. It was hypothesized that echocardiographic LA volume index (LAVI) predicts heart failure (HF) hospitalization and mortality with similar statistical power as left ventricular ejection fraction (LVEF) in a...
7,575
Enhanced proinflammatory response of mononuclear cells to in vitro LPS-challenge in patients with ventricular fibrillation in the setting of acute myocardial infarction.
Ventricular fibrillation (VF) in the setting of acute myocardial infarction (AMI) is the leading cause of sudden cardiac death. A potential role of intrinsic, subclinical inflammatory states in patients suffering from ischemia-related VF has not been investigated yet. The aim of the present study was (i) to examine ser...
7,576
[Therapeutic hypothermia in neurocritical patients].
Induced hypothermia in neurocritical patients is one of the most promising neuroprotective therapies in the last decade. Unfortunately, the promising results obtained in experimental studies have had an unequal reflection in the different diseases that affect the neurocritical patient. The use of therapeutic hypothermi...
7,577
[Heart failure in outpatients: comorbidities and management by different specialists. The EPISERVE Study].
The aim of the EPISERVE study was to investigate the clinical characteristics of heart failure in outpatients and its diagnostic and therapeutic management by cardiology, internal medicine and primary care specialists.</AbstractText>The study involved 507 physicians working in primary care (n=181, 36%), cardiology (n=1...
7,578
Sex difference and factors associated with outcome in patients with sustained ventricular arrhythmias.
To describe gender differences and factors of importance for outcome in patients referred for sustained ventricular arrhythmias.</AbstractText>Two hundred and fifty three patients took part in the survey, 126 (20 women) had sustained monomorphic ventricular tachycardia (VT) and 127 (31 women) had polymorphic VT/ventric...
7,579
Role of extracorporeal circulation in the management of accidental deep hypothermia.
Deep hypothermia leading to cardiac arrest requires aggressive management for resuscitation. Various methods are available to rewarm the patient. We hereby present a case report where active resuscitation was carried out using cardiopulmonary bypass in a young female who was found unconscious with a core temperature of...
7,580
Rhythm control versus rate control for atrial fibrillation and heart failure.
It is common practice to restore and maintain sinus rhythm in patients with atrial fibrillation and heart failure. This approach is based in part on data indicating that atrial fibrillation is a predictor of death in patients with heart failure and suggesting that the suppression of atrial fibrillation may favorably af...
7,581
[Ventricular tachyarrhythmias in patients with cardiomyopathy].
The purpose of this study was to determine the number and distribution of cardiomyopathies as the aetiology of ventricular tachyarrhythmias among patients discharged from the Department of Cardiology, Rigshospitalet.</AbstractText>The study was a retrospective review of patients discharged with the diagnostic codes ven...
7,582
[Ventricular tachyarrhythmias. A retrospective analysis of etiology, demography and treatment].
The aim of this study was to investigate the age, sex, etiology, frequency of implantable cardioverter-defibrillator (ICD) and previous cardiac arrest among patients discharged from the Department of Cardiology, Rigshospitalet (Copenhagen University Hospital), Denmark, due to ventricular tachyarrhythmias.</AbstractText...
7,583
The effect of aprotinin on risk of acute renal failure requiring dialysis after on-pump cardiac surgery.
The use of aprotinin in cardiac surgery to reduce perioperative bleeding and transfusion is controversial. We assessed the effect of aprotinin on the risk of acute renal failure in 423 patients who underwent on-pump cardiac surgery between January 1, 2005 and December 31, 2006. Of these 423 patients, 318 (75.2%) receiv...
7,584
Etiology, pathophysiology, and treatment of atrial fibrillation: part 1.
Atrial fibrillation (AF) is associated with a higher incidence of mortality, stroke, and coronary events than is sinus rhythm. AF with a rapid ventricular rate may cause a tachycardia-related cardiomyopathy. Immediate direct-current cardioversion should be performed in patients with AF and acute myocardial infarction, ...
7,585
The Brugada type 1 electrocardiographic pattern is common among Filipinos.
To measure the prevalence of the Brugada type 1 ECG pattern in the general population in the Philippines. STUDY SETTING AND DESIGN: Sudden unexplained death syndrome is rare in the West but is common among Southeast Asians. Ventricular fibrillation is the terminal event. The Brugada type 1 electrocardiographic (ECG) pa...
7,586
Acoustic cardiographic recording during ventricular fibrillation.
This is the second case report in literature that describes the simultaneous acoustic cardiographic, electrocardiographic, and invasive hemodynamic events that occurred before, during and after ventricular fibrillation that was successfully cardioverted to sinus rhythm. The absence of heart sounds, which are linked to ...
7,587
A manikin-based observational study on cardiopulmonary resuscitation skills at the Osaka Senri medical rally.
To examine the current status and problems of resuscitation management in Japan as demonstrated at the 2006 and 2007 Osaka Senri medical rallies.</AbstractText>Using manikins, the quality of resuscitation was evaluated in 33 teams that participated in the medical rallies. The challenge was to deliver defibrillation sho...
7,588
A national scheme for public access defibrillation in England and Wales: early results.
Automated external defibrillators (AEDs) operated by lay persons are used in the UK in a National Defibrillator Programme promoting public access defibrillation (PAD).</AbstractText>Two strategies are used: (1) Static AEDs installed permanently in busy public places operated by those working nearby. (2) Mobile AEDs ope...
7,589
Limits of conventional therapies after prolonged normovolemic cardiac arrest in swine.
Patients' outcomes after prolonged cardiac arrest are often grim. The aim of this study was to find the longest period of normovolemic, normothermic, cardiac arrest no-flow after which good neurologic outcome can be achieved with conventional therapies.</AbstractText>Swine (28-37 kg) were subjected to ventricular fibri...
7,590
[Out-of-hospital sudden cardiac arrest in the population of adults in Szczecin, years 2002-2003].
Out-of-hospital cardiac arrest, with its high fatality rate, is a significant public health issue.</AbstractText>The survival of 421 patients with out-of-hospital cardiac arrest, who after the resuscitation were admitted to intensive care units in Szczecin in 2002-2003, was investigated. The outcome was analysed at two...
7,591
Analyzing the electrophysiological effects of local epicardial temperature in experimental studies with isolated hearts.
As a result of their modulating effects upon myocardial electrophysiology, both hypo- and hyperthermia can be used to study the mechanisms that generate or sustain cardiac arrhythmias. The present study describes an original electrode developed with thick-film technology and capable of controlling regional temperature ...
7,592
Intravenous magnesium for cardiac arrhythmias: jack of all trades.
Intravenous magnesium has been used to prevent and treat many different types of cardiac arrhythmia. It has diverse electrophysiological actions on the conduction system of the heart; including prolonging sinus node recovery time, and reducing automaticity, atrioventricular nodal conduction, antegrade and retrograde co...
7,593
Effect of chest compressions only during experimental basic life support on alveolar collapse and recruitment.
The importance of ventilatory support during cardiac arrest and basic life support is controversial. This experimental study used dynamic computed tomography (CT) to assess the effects of chest compressions only during cardiopulmonary resuscitation (CCO-CPR) on alveolar recruitment and haemodynamic parameters in porcin...
7,594
Shock outcome prediction before and after CPR: a comparative study of manual and automated active compression-decompression CPR.
We report on a study designed to compare the relative efficacy of manual CPR (M-CPR) and automated mechanical CPR (ACD-CPR) provided by an active compression-decompression (ACD) device. The ECG signals of out-of-hospital cardiac arrest patients of cardiac aetiology were analysed just prior to, and immediately after, ca...
7,595
Low levels of cellular omega-3 increase the risk of ventricular fibrillation during the acute ischaemic phase of a myocardial infarction.
Animal studies have demonstrated evidence of an anti-arrhythmic effect of marine n-3 fatty acids (FAs). In humans the same mechanism may explain the observed reduction in sudden cardiac death (SCD) associated with intake of fish. Whether high levels of n-3 FAs could protect against ventricular fibrillation (VF) during ...
7,596
Recurrent ventricular fibrillation during advanced life support care of patients with prehospital cardiac arrest.
The response of recurrent episodes of ventricular fibrillation (VF) to defibrillation shocks has not been systematically studied. We analyzed outcomes from countershocks delivered for VF during advanced life support (ALS) care of patients with out-of-hospital cardiac arrest.</AbstractText>Cohort of patients with prehos...
7,597
Intracellular calcium dynamics and acetylcholine-induced triggered activity in the pulmonary veins of dogs with pacing-induced heart failure.
Heart failure increases autonomic nerve activities and changes intracellular calcium (Ca(i)) dynamics.</AbstractText>The purpose of this study was to investigate the hypothesis that abnormal Ca(i) dynamics are responsible for triggered activity in the pulmonary veins (PVs) during acetylcholine infusion in a canine mode...
7,598
Mild therapeutic hypothermia shortens intensive care unit stay of survivors after out-of-hospital cardiac arrest compared to historical controls.
Persistent coma is a common finding after cardiac arrest and has profound ethical and economic implications. Evidence suggests that therapeutic hypothermia improves neurological outcome in these patients. In this analysis, we investigate whether therapeutic hypothermia influences the length of intensive care unit (ICU)...
7,599
Sudden death in a young man with catecholaminergic polymorphic ventricular tachycardia and paroxysmal atrial fibrillation.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial condition that presents with exercise-induced syncope or sudden death in children or young adults. In most cases the disease is caused by a mutation in the cardiac ryanodine receptor (RyR2) gene. Current evidence suggests that primary therapy fo...