Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
7,700 | Heart rate variability measures during sinus rhythm predict cycle length entropy during atrial fibrillation. | Several noninvasive measures of cardiac risk such as heart rate variability (HRV) cannot be used in patients with atrial fibrillation (AF). One promising exception is the measure of ventricular cycle length entropy (VCLE) where initial data suggest that a reduction in VCLE portends an increased risk of cardiac death in... |
7,701 | Long-term clinical efficacy and risk of catheter ablation for atrial fibrillation in the elderly. | The number of elderly patients with atrial fibrillation (AF) is increasing rapidly, and the safety and efficacy of catheter ablation in this demographic group has not been established.</AbstractText>Over a 7-year period we studied 1,165 consecutive patients undergoing 1,506 AF ablation procedures using a consistent abl... |
7,702 | Future directions in cardiac resynchronization therapy. | Cardiac resynchronization therapy (CRT) reduces symptoms and improves mortality in patients with moderate to severe chronic heart failure (New York Heart Association class III-IV) in sinus rhythm with reduced left ventricular ejection fraction and with wide QRS on the surface electrocardiogram as evidence of ventricula... |
7,703 | Factors predicting the time until atrial fibrillation recurrence after concomitant left atrial ablation. | Treatment of atrial fibrillation, a risk factor for morbidity and mortality, by left atrial ablation is a less complex procedure which is increasingly performed in conjunction with surgery for various heart diseases. Although restoration of sinus rhythm is effective initially, atrial fibrillation may recur. We investig... |
7,704 | Ventricular tachyarrhythmia as a primary presentation of sarcoidosis. | Sarcoidosis is a multisystem, granulomatous disease with occasional cardiac manifestations. The clinical course of patients with ventricular tachyarrhythmias as a primary presentation of sarcoidosis is mostly unknown.</AbstractText>We describe nine patients (four males and five females) in whom sarcoidosis manifested a... |
7,705 | Effects of garlic on the induction of ventricular fibrillation. | Previous studies have shown that oral and intravenous administrations of garlic provide a significant antiarrhythmic effect and improve defibrillation efficacy. We tested the hypothesis that garlic could decrease the inducibility of ventricular arrhythmia.</AbstractText>Twenty-one pigs (25-30 kg) were divided into thre... |
7,706 | Prevention and management of perioperative arrhythmias in the thoracic surgical population. | Although bradyarrhythmias or malignant ventricular tachyarrhythmias have been reported in less than 1% of patients following noncardiac surgery, rapid atrial arrhythmias more frequently affect the elderly who undergo thoracic operations. This article focuses on new issues leading to the improved understanding of the pa... |
7,707 | Analysis of benign ventricular tumors: long-term outcome after resection. | We sought to compare clinical and pathologic characteristics of ventricular tumors and to detect whether differences exist in short- and long-term survival after resection.</AbstractText>From 1964 to 2005, 323 patients had cardiac surgery for resection of primary cardiac tumors; 53 (16%) patients had primary ventricula... |
7,708 | Ventricular late potentials: a critical overview and current applications. | More than 450 000 Americans die suddenly each year from sustained ventricular tachycardia (VT) or fibrillation. Overall, event rates in Europe are similar to those in the United States. A correct risk stratification is essential to reduce the incidence of sudden cardiac death. Ventricular late potentials (VLPs) represe... |
7,709 | Repolarization heterogeneity in the right ventricular outflow tract: correlation with ventricular arrhythmias in Brugada patients and in an in vitro canine Brugada model. | Brugada syndrome (BrS) is characterized by repolarization abnormality with ST-segment elevation in the right ventricular outflow tract (RVOT).</AbstractText>Although action potential (AP) heterogeneity is associated with induction of ventricular arrhythmias (VA) in BrS, clinical evidence and its experimental correlatio... |
7,710 | High amplitude T-wave alternans precedes spontaneous ventricular tachycardia or fibrillation in ICD electrograms. | T-wave alternans (TWA) increases acutely prior to ventricular tachycardia (VT) or fibrillation (VF) in animal studies, suggesting that it may provide a warning for VT/VF in implantable cardioverter defibrillator (ICD) patients. Clinically, measurement of surface ECG TWA requires preprocessing the input signal to reduce... |
7,711 | Post-infarction ventricular arrhythmias originating in papillary muscles. | The aim of this study was to define the role of papillary muscles (PAPs) in post-infarction ventricular arrhythmias.</AbstractText>Papillary muscles have been implicated in arrhythmogenesis; however, their role in post-infarction ventricular arrhythmias has not been well-defined.</AbstractText>In a series of 9 patients... |
7,712 | Cerebrovascular risk factors and incident depression in community-dwelling elderly. | The 'vascular depression' hypothesis suggests that late-life depression results from vascular brain damage. We studied the longitudinal association between cerebrovascular risk factors and incident depression in a large population-based study.</AbstractText>Two thousand nine hundred and thirty-one persons with the age ... |
7,713 | Brugada syndrome with complete right bundle branch block disclosed by a febrile illness. | The characteristic of right-bundle branch block (RBBB) pattern in Brugada syndrome (BS) is an atypical pattern without a wide S wave in left leads. We present a case of a patient with BS who had a typical ECG pattern of complete RBBB (CRBBB) with a wide S wave in the left leads which was disclosed by a febrile illness.... |
7,714 | Comparison of the Cerebral Performance Category score and the Health Utilities Index for survivors of cardiac arrest. | The Cerebral Performance Category score is an easy to use but unvalidated measure of functional outcome after cardiac arrest. We evaluate the comparability of results from the Cerebral Performance Category scale versus those of the validated but more complex Health Utilities Index scale for health-related quality of li... |
7,715 | Clinical and echocardiographic measures governing thromboembolism destination in atrial fibrillation. | Although infrequent, embolic occlusion to non-cerebral arteries may result in limb loss, organ failure, and death. The aim of this study was to define clinical and echocardiographic characteristics determining thromboembolism destination in non-valvular atrial fibrillation. An inception cohort of individuals (n=72) wer... |
7,716 | Serum transforming growth factor-beta1 as a risk stratifier of sudden cardiac death. | Sudden cardiac death prematurely claims the lives of some 7 million each year worldwide. It occurs primarily in patients with an underlying structural cardiac abnormality, and regardless of the type of the underlying pathology (heart failure, dilated and hypertrophic cardiomyopathies, myocardial infarction and aging), ... |
7,717 | Vernakalant--a promising therapy for conversion of recent-onset atrial fibrillation. | This paper reviews the pharmacology, electrophysiology, efficacy and safety of intravenous and oral vernakalant hydrochloride (RSD-1235), a novel antiarrhythmic drug that has relative atrial selectivity by blocking potassium channels that are present in the atria and not the ventricle. In addition, this drug has import... |
7,718 | Paroxysmal atrial fibrillation in critically ill patients with sepsis. | The objective of this retrospective cohort study was to describe the incidence of paroxysmal atrial fibrillation and to determine its risk factors and effect on outcome in critically ill patients with sepsis. The study included 81 patients with sepsis admitted to an intensive care unit. In all, 25 patients (31%) develo... |
7,719 | Less invasive intracardiac surgery performed without aortic clamping. | Aortic clamping and cardioplegia delivery add complexity to performing intracardiac procedures through a right minithoracotomy. Recent publications have shown excellent patient outcomes after mitral valve (MV) procedures undertaken through thoracotomy on the fibrillating heart. We reviewed our experience with this appr... |
7,720 | Clinical significance of B-type natriuretic Peptide in the assessment of untreated hypertension. | Recent studies suggest that B-type natriuretic peptide (BNP) is an important predictor of cardiac events in hypertensive patients.</AbstractText>The relationship between the plasma BNP level and various clinical parameters was examined in 154 untreated hypertensive patients without heart failure or atrial fibrillation ... |
7,721 | Comparison of rate and rhythm control in hypertension patients with atrial fibrillation. | Atrial fibrillation (AF) is a very common cardiac arrhythmia, and is associated with an increased mortality in patients with hypertension. Whether the best therapeutic approach for these patients is to restore sinus rhythm (SR) or to adequately control the ventricular rate is still controversial. The aim of this study ... |
7,722 | Reducing false alarm rates for critical arrhythmias using the arterial blood pressure waveform. | Over the past two decades, high false alarm (FA) rates have remained an important yet unresolved concern in the Intensive Care Unit (ICU). High FA rates lead to desensitization of the attending staff to such warnings, with associated slowing in response times and detrimental decreases in the quality of care for the pat... |
7,723 | Optimal heart failure therapy and successful cardioversion in heart failure patients with atrial fibrillation. | Effectiveness, safety, and other factors associated with success of cardioversion (CV) of atrial fibrillation (AF) have not yet been evaluated in patients with reduced left ventricular ejection fraction. We studied 148 consecutive patients with left ventricular dysfunction (ejection fraction < or = 45%), who underwe... |
7,724 | Brugada syndrome with marked conduction disease: dual implications of a SCN5A mutation. | A 51-year-old woman presented with an episode of syncope. Upon further review she was found to have a typical Brugada type pattern on her electrocardiogram. She did not have evidence for structural heart disease. At electrophysiological testing she was found to have marked infrahisian conduction disease and had easily ... |
7,725 | Stimulation rate and the optimal interventricular interval during cardiac resynchronization therapy in patients with chronic atrial fibrillation. | Optimization of cardiac resynchronization therapy (CRT) with respect to the interventricular (V-V) interval is mainly limited to pacing at a resting heart rate. We studied the effect of higher stimulation rates with univentricular and biventricular (BiV) pacing modes including the effect of the V-V interval optimizatio... |
7,726 | The impedance cardiogram recorded through two electrocardiogram/defibrillator pads as a determinant of cardiac arrest during experimental studies. | Laypersons are poor at emergency pulse checks (sensitivity 84%, specificity 36%). Guidelines indicate that pulse checks should not be performed. The impedance cardiogram (dZ/dt) is used to assess stroke volume. Can a novel defibrillator-based impedance cardiogram system be used to distinguish between circulatory arrest... |
7,727 | Automatic home monitoring of implantable cardioverter defibrillators. | With the expanding indications for implantable cardioverter defibrillator (ICD) and reports of unexpected ICD failures, home monitoring (HM) was proposed to decrease follow-up workload and increase patient safety. Home monitoring implantable cardioverter defibrillators offer wireless, everyday transfer of ICD status an... |
7,728 | [Drugs for cardiac arrest]. | After publication of the 2005 international recommendations on resuscitation, a French panel of experts on cardiac arrest published guidelines adapted to French practice. Despite the absence of placebo-controlled trials, adrenaline remains the standard vasopressor for cardiac arrest, at a dose of 1 mg about every 4 min... |
7,729 | Myocardial delayed contrast enhancement in patients with arterial hypertension: initial results of cardiac MRI. | In arterial hypertension left ventricular hypertrophy comprises myocyte hypertrophy, interstitial fibrosis and structural alterations of the coronary microcirculation. MRI enables the detection of myocardial fibrosis, infarction and scar tissue by delayed enhancement (DE) after contrast media application. Aim of this s... |
7,730 | Unusual cause of exercise-induced ventricular fibrillation in a well-trained adult endurance athlete: a case report. | The diseases responsible for sudden deaths in athletes differ considerably with regard to age. In young athletes, congenital malformations of the heart and/or vascular system cause the majority of deaths and can only be detected noninvasively by complex diagnostics. In contrast, in older athletes who die suddenly, athe... |
7,731 | Left atrial giant thrombus infected by Escherichia Coli. Case report. | Left atrial thrombi are mostly related to mitral valve disease. The differential diagnosis of clots and myxomas in the left atrium is mostly based on echocardiography. Infection of intracardiac thrombi is extremely rare and mostly reported in ventricular clots or aneurysms following myocardial infarction.</AbstractText... |
7,732 | [Predictors of efficacy initial low energy of external rectilinear biphasic cardioversion in persistent atrial fibrillation]. | Rectilinear biphasic cardioversion (Bi-DC) has been shown to be very effective for restoration of sinus rhythm in patients with persistent atrial fibrillation (AF). There is, however, limited information on factors influencing effectiveness of the initial energy of 50 J for Bi-DC of atrial fibrillation.</AbstractText>E... |
7,733 | Usefulness and predictive value of circulating NT-proBNP levels to stratify patients for referral and priority treatment in a specialized outpatient heart failure center. | Serum natriuretic peptide levels are useful diagnostic and prognostic markers in patients with acute decompensated heart failure, but have been little used to stratify urgency of treatment in the outpatient situation.</AbstractText>To examine the use of natriuretic peptide to guide priority of patient referral to a hea... |
7,734 | Cardiac arrhythmias in Thai Acute Coronary Syndrome Registry. | The incidence of arrhythmic complications in Thai patients with acute coronary syndromes (ACS) has not been previously reported. The present study results will serve as the local database for future studies.</AbstractText>To evaluate the incidence of arrhythmic complications in ASC in Thai patients and to identify fact... |
7,735 | Is use of temporary pacing wires following coronary bypass surgery really necessary? | Temporary epicardial pacing wires (TEPW) which are routinely used after coronary bypass grafting may result in significant complications. We sought to identify variables that predict TEPW implantation and thereby limit their use.</AbstractText>This prospective study enrolled 564 patients (296 underwent coronary artery ... |
7,736 | Therapeutic hypothermia with a novel surface cooling device improves neurologic outcome after prolonged cardiac arrest in swine. | Devices for rapid induction of mild hypothermia after cardiac arrest are needed. We hypothesized that the Life Recovery Systems' ThermoSuit System provides effective core cooling by pumping ice water over the skin surface and improves neurologic outcome after prolonged cardiac arrest.</AbstractText>Prospective experime... |
7,737 | Prearrest administration of low-molecular-weight heparin in porcine cardiac arrest: hemodynamic effects and resuscitability. | Both animal and human studies demonstrate activation of coagulation during cardiac arrest. Prearrest anticoagulation is used routinely in many experimental studies. We studied the hemodynamic effects of prearrest anticoagulation with a low-molecular-weight heparin suitable for clinical use during cardiopulmonary resusc... |
7,738 | Selective retrograde venous revascularization of the myocardium when PCI or CABG is impossible: investigation in a porcine model. | We investigated the possibility of nourishing the myocardium through selective retrograde coronary venous bypass grafting (CVBG) with an off-pump technique and evaluated various methods of monitoring the physiological effects of this procedure. In a porcine model, the left internal mammary artery (LIMA) was anastomosed... |
7,739 | Evaluation of left ventricular long-axis function in cases of rheumatic pure mitral stenosis with atrial fibrillation. | Using tissue Doppler echocardiography, we evaluated left ventricular long-axis function in 65 mitral stenosis patients, 30 of whom were in sinus rhythm and 35 of whom were in chronic atrial fibrillation. There were 35 healthy control subjects. Conventional echocardiography was used to evaluate left ventricular diameter... |
7,740 | Novel transient outward and ultra-rapid delayed rectifier current antagonist, AVE0118, protects against ventricular fibrillation induced by myocardial ischemia. | AVE0118 is a novel drug that blocks the transient outward current (Ito), the ultra rapid component of the delayed rectifier current (IKur), and the acetylcholine dependent potassium channel (IKach). The latter 2 channels are more abundant in atrial tissue. It is possible that AVE0118 could reduce regional differences i... |
7,741 | Development and validation of diagnostic criteria for atrial flutter on the surface electrocardiogram. | There are no universally accepted ECG diagnostic criteria for atrial flutter (AFL), making its differentiation from "coarse" atrial fibrillation (AF) difficult.</AbstractText>To develop diagnostic criteria for AFL, we examined two sets of ECGs. Set 1 consisted of 100 ECGs (50 AF, AFL) with diagnoses confirmed by intrac... |
7,742 | Adverse effects of continuous ventricular pacing in patients with slower atrial fibrillation and normal left ventricular systolic function. | Both heart rate irregularity during chronic atrial fibrillation (AF) and ventricular desynchronization imposed by ventricular pacing may compromise ventricular function. We investigated whether heart rhythm regularization achieved through ventricular overdrive pacing (VP) gives additional benefit over rate control alon... |
7,743 | Multiple source surveillance incidence and aetiology of out-of-hospital sudden cardiac death in a rural population in the West of Ireland. | There is a paucity of published data on prospectively identified rates of out-of-hospital sudden cardiac death (SCD). We sought to determine the incidence, survival and aetiology of out-of-hospital SCD in the West of Ireland for the year 2005.</AbstractText>Data from emergency room resuscitation records were collected ... |
7,744 | 3D and 4D echo--applications in EP laboratory procedures. | 3D echocardiography allows imaging and analysis of cardiovascular structures as they move in time and space, thus creating possibility for creation of 4D datasets (3D + time). Intracardiac echocardiography (ICE) further broadens the spectrum of echocardiographic techniques by allowing detailed imaging of intracardiac a... |
7,745 | Intramural foci during long duration fibrillation in the pig ventricle. | For more than 50 years, it has been assumed that ventricular fibrillation (VF) is maintained solely by reentry in the working myocardium. This hypothesis has never been tested by recording VF with electrodes spaced sufficiently close to map activation sequences in 3D. We recorded the first 10 minutes of electrically in... |
7,746 | Antiarrhythmogenic effect of reconstituted high-density lipoprotein against ischemia/reperfusion in rats. | This study analyzed the antiarrhythmogenic effect of reconstituted high-density lipoprotein (rHDL) against ischemia/reperfusion in vivo.</AbstractText>Recent studies have suggested that a reduction in the plasma HDL level may contribute to cardiac sudden death. Although there are currently only a few therapeutic strate... |
7,747 | [Impact of atrial fibrillation on prognosis of chronic heart failure patients with left ventricular ejection fraction>or=0.5]. | To explore the prevalence, distribution type and impact of atrial fibrillation on prognosis of hospitalized patients with congestive heart failure (CHF) with left ventricular ejection fraction (LVEF)>or=0.50.</AbstractText>The medical records of 417 unselected consecutive patients with CHF were retrospectively revie... |
7,748 | Implantable cardioverter defibrillator therapy: ten years experience in a medical center. | An implantable cardioverter defibrillator (ICD) is the therapy of choice for survivors of life-threatening ventricular tachyarrhythmias or sudden cardiac death. To date there is little data concerning the clinical features and outcome of ICD therapy among Taiwanese. This study identifies factors related to the outcome ... |
7,749 | Hypothermia and neurological outcome after cardiac arrest: state of the art. | Multi-centred studies in patients who remain comatose after cardiac arrest and also in newborn babies with perinatal asphyxia have clearly demonstrated that mild hypothermia (32-34 degrees C) can improve neurological outcome after post-anoxic injury. This represents a highly promising development in the field of neuroc... |
7,750 | Drugs that interact with cardiac electro-mechanics: old and new targets for treatment. | The concept of mechano-electrical feedback was derived from the observation that a short stretch applied to the beating heart can invoke an electrical response in the form of an afterdepolarization or a premature ventricular beat. More recent work has identified stretch-activated channels whose specific inhibition migh... |
7,751 | Anti-arrhythmic and vasopressor medications for the treatment of ventricular fibrillation in severe hypothermia: a systematic review of the literature. | To determine the rate of return of spontaneous circulation (ROSC) in animal models performing resuscitation from induced ventricular fibrillation (VF) in severe hypothermia (<30 degrees C).</AbstractText>A medical literature database search from 1966 to present was performed identifying placebo controlled trials usi... |
7,752 | Liquid ventilation with perfluorocarbons facilitates resumption of spontaneous circulation in a swine cardiac arrest model. | Induced external hypothermia during ventricular fibrillation (VF) improves resuscitation outcomes. Our objectives were twofold (1) to determine if very rapid hypothermia could be achieved by intrapulmonary administration of cold perfluorocarbons (PFC), thereby using the lungs as a vehicle for targeted cardiopulmonary h... |
7,753 | Dynamics and state transitions during resuscitation in out-of-hospital cardiac arrest. | The state or rhythm during resuscitation, i.e. ventricular fibrillation/tachycardia (VF/VT), asystole (ASY), pulseless electrical activity (PEA), or return of spontaneous circulation (ROSC) determines management. The state is unstable and will change either spontaneously (e.g. PEA-->ASY) or by intervention (e.g. VF-... |
7,754 | [Benefits of cardiac resynchronization therapy in patients with atrial fibrillation who have not undergone atrioventricular node ablation]. | The aim of this study was to compare the effects of cardiac resynchronization therapy on left ventricular function and reverse remodeling in patients in sinus rhythm with the effects in patients with atrial fibrillation who have not undergone atrioventricular node ablation. Echocardiographic and clinical parameters wer... |
7,755 | [Changes in the spectral characteristics of ventricular fibrillation in lesions produced by radiofrequency ablation. An experimental study]. | Although electro- physiological databases contain information about changes in the time domain in lesions produced by radiofrequency ablation, very few data on changes in the frequency domain are available. The aim of this study was to investigate changes in the spectral characteristics of ventricular fibrillation in z... |
7,756 | Diagnostic approach and treatment strategy in tachycardia-induced cardiomyopathy. | Due to the absence of differential guidelines for heart failure with tachyarrhythmia, it is difficult to diagnose tachycardia-induced cardiomyopathy (TIC) at the initial visit. Furthermore, clinical outcomes of rate versus rhythm control in TIC are unclear.</AbstractText>Because the etiology of TIC is different from dy... |
7,757 | Comparison of standard and bicaval approach in orthotopic heart transplantation: 10-year follow-up. | The present study compared 86 patients who underwent orthotopic heart transplantation by bicaval and standard techniques.</AbstractText>Patients already followed in the first year after heart transplantation were studied at 10 years of follow-up, this time evaluating the prevalence of arrhythmias, conduction disturbanc... |
7,758 | Direction of signal recording affects waveform characteristics of ventricular fibrillation in humans undergoing defibrillation testing during ICD implantation. | In cardiac arrest due to prolonged ventricular fibrillation (VF), defibrillation is more likely to result in a perfusing rhythm if chest compressions are performed first. Furthermore, the VF waveform can predict the shockability of VF and thus automated external defibrillators (AEDs) are being designed to analyze the V... |
7,759 | Aortic valve replacement for low-flow/low-gradient aortic stenosis operative risk stratification and long-term outcome: a European multicenter study. | We evaluated a large multicenter series of patients operated on for low-flow/low-gradient aortic stenosis (LF/LGAS) to stratify the operative risk, assess whether perioperative mortality has decreased over recent years, and analyze the post-operative outcome.</AbstractText>Although LF/LGAS is classically associated wit... |
7,760 | A randomized comparison of triple-site versus dual-site ventricular stimulation in patients with congestive heart failure. | We compared the effects of triple-site versus dual-site biventricular stimulation in candidates for cardiac resynchronization therapy.</AbstractText>Conventional biventricular stimulation with a single right ventricular (RV) and a single left ventricular (LV) lead is associated with persistence of cardiac dyssynchrony ... |
7,761 | Right ventricular endomyocardial fibrosis. | Endomyocardial fibrosis (EMF) is a neglected tropical cardiomyopathy of unknown etiology and pathogenesis that is common in certain tropical areas of Africa, Asia, and South America. It affects predominantly children and young adults. Endocardial fibrosis is the hallmark of this restrictive cardiomyopathy leading to re... |
7,762 | Association of echocardiographic atrial size and atrial fibrosis in a sequential model of congestive heart failure and atrial fibrillation. | Cardioversion (CV) success of atrial fibrillation (AF) inversely correlates to the size of the left atrium (LA). Atrial fibrillation and its most important risk factor, congestive heart failure (CHF), both induce atrial structural enlargement and fibrosis. To investigate the effect of AF and CHF on atrial dilatation an... |
7,763 | [Ventricular repolarisation disorders and long QT syndrome: clinical and genetic study in 10 paediatric cases]. | We report 10 paediatric cases of ventricular repolarisation disorders and long QT syndrome, which differed in their mode of revelation, from asymptomatic forms to syncope events or heart arrest. Diagnosis is based on electrophysiological explorations and exhaustive genetic investigation. It allows a well-codified preve... |
7,764 | Identification of a novel KCNQ1 mutation associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long QT syndrome in a Chinese family. | Long QT syndrome (LQTS) is a cardiac disorder characterized by prolonged QT intervals on electrocardiograms (ECG), ventricular arrhythmias, and sudden death. Clinically, two inherited forms of LQTS have been defined: autosomal dominant LQTS or Romano-Ward syndrome (RWS) not associated with deafness and autosomal recess... |
7,765 | Inducibility of atrial and ventricular arrhythmias along the ligament of marshall: role of autonomic factors. | The mechanism(s) underlying atrial fibrillation (AF) initiation along the ligament of Marshall (LOM) remains controversial.</AbstractText>We sought to examine the role of the autonomic nervous system in arrhythmogenesis along the LOM.</AbstractText>In 31 anesthetized dogs, a left thoracotomy exposed the LOM. During atr... |
7,766 | Effect of cardiac resynchronization therapy in isolated ventricular noncompaction in adults: follow-up of four cases. | An isolated ventricular noncompaction (IVNC) is an unclassified cardiomyopathy and, despite the increasing awareness of and interest in this disorder, the role of cardiac resynchronization therapy (CRT) remains obscure.</AbstractText>The purpose of this study was to clarify the long-term effect of CRT on IVNC in adult ... |
7,767 | Downregulation of the calcium current in human right atrial myocytes from patients in sinus rhythm but with a high risk of atrial fibrillation. | A decrease in L-type calcium current (ICaL) is an important mechanism favouring atrial fibrillation (AF). Here, we aimed to identify pathogenic factors associated with ICaL downregulation.</AbstractText>Atrial myocytes were isolated from right atrial appendages obtained from 86 adult patients in sinus rhythm with coron... |
7,768 | Cardiac involvement in adults with Pompe disease. | Glycogen storage disease type II or Pompe disease is a neuromuscular disorder caused by deficiency of lysosomal acid alpha- glucosidase. Classic infantile Pompe disease results in massive left ventricular (LV) hypertrophy and failure. Although Pompe disease is often included in the differential diagnosis of LV hypertro... |
7,769 | Phantom shocks in patients with an implantable cardioverter defibrillator. | Phantom shock is the sensation of shock in the absence of an actual implantable cardioverter-defibrillator (ICD) discharge. The ICD is now the first-line therapy for patients with ventricular tachycardia and fibrillation. There has been a significant increase in the number of patients with an ICD and patients presentin... |
7,770 | ICD patients with elevated defibrillation threshold: clinical behavior and therapeutic alternatives. | The ideal programming of the implantable cardioverter defibrillator (ICD) shock energy should be at least 10J above the defibrillation threshold (DFT), requiring alternative techniques when the DFT is elevated.</AbstractText>To assess the clinical behavior of ICD patients with DFT>25J and the efficacy of the chosen ... |
7,771 | Arterial stiffness is associated with left atrial size in hypertensive patients. | Arterial stiffness is a strong predictor of cardiovascular events and particularly of stroke. A likely explanation is the development of atherosclerotic lesions at the carotid level, favored by increased local stiffness. Another possibility involves cardiac consequences of aortic stiffness and particularly left atrial ... |
7,772 | Death without prior appropriate implantable cardioverter-defibrillator therapy: a competing risk study. | Implantable cardioverter-defibrillators (ICDs) improve survival in selected patients with left ventricular systolic dysfunction in randomized trials. Competing death without prior appropriate ICD therapy might preclude benefit from ICD implantation in a less selected routine-care population.</AbstractText>We selected a... |
7,773 | Atrial fibrillation and isolated systolic hypertension: the systolic hypertension in the elderly program and systolic hypertension in the elderly program-extension study. | We performed a post hoc analysis of the Systolic Hypertension in the Elderly Program database to assess the incidence of atrial fibrillation in the elderly hypertensive population, its influence on cardiovascular events, and whether antihypertensive treatment can prevent its onset. The Systolic Hypertension in the Elde... |
7,774 | Long-term survival in patients undergoing cardiac resynchronization therapy: the importance of performing atrio-ventricular junction ablation in patients with permanent atrial fibrillation. | To investigate the effects of cardiac resynchronization therapy (CRT) on survival in heart failure (HF) patients with permanent atrial fibrillation (AF) and the role of atrio-ventricular junction (AVJ) ablation in these patients.</AbstractText>Data from 1285 consecutive patients implanted with CRT devices are presented... |
7,775 | Incidence and prognosis of sustained arrhythmias in critically ill patients. | Sustained arrhythmias are common in postoperative and cardiac intensive care units (ICUs), but their incidence and prognosis in general ICUs have never been reported.</AbstractText>To estimate the incidence and prognosis of sustained arrhythmias in a general ICU population.</AbstractText>Prospective, multicenter, 1-mon... |
7,776 | Impact of percutaneous transluminal septal myocardial ablation on refractory paroxysmal atrial fibrillation in patients with hypertrophic obstructive cardiomyopathy. | Atrial fibrillation is commonly observed in patients with hypertrophic obstructive cardiomyopathy. Episodes of paroxysmal atrial fibrillation are often torturous and limit the quality of life by causing congestive heart failure, transient hypotension, or bradycardia. Control of paroxysmal atrial fibrillation in patient... |
7,777 | Coronary collateral circulation: any effect on P-wave dispersion? | Coronary collateral circulation determines the severity of ischemic myocardial damage. Increased P-wave dispersion is an independent predictor for atrial fibrillation. Consistent evidence is little about the relation between coronary collateral circulation and arrhythmia risk. In this article, the effect of coronary co... |
7,778 | Chemical preconditioning effect of 3-nitropropionic acid in anesthetized rat heart. | Short ischemic episodes increase tolerance against subsequent severe ischemia in the heart. Nitropropionate (3-NP), an irreversible inhibitor of succinic dehydrogenase of the mitochondrial complex II, was shown to induce protective effect against ischemic brain injury. The aim of this study was to investigate the possi... |
7,779 | Ataxia caused by amiodarone in older people. | Amiodarone is recommended for the cardioversion of atrial fibrillation and prevention of paroxysmal atrial fibrillation in patients with structural heart disease, coronary artery disease or left ventricular dysfunction. It has well-recognised side-effects on the skin, lungs, liver, thyroid and eyes. Neurological side-e... |
7,780 | Catheter ablation of paroxysmal atrial fibrillation improves cardiac function: a prospective study on the impact of atrial fibrillation ablation on left ventricular function assessed by magnetic resonance imaging. | Beneficial effects of atrial fibrillation (AF) ablation have been demonstrated in patients with congestive heart failure (CHF) and significantly impaired left ventricular ejection fraction (LVEF). However, the impact of pulmonary vein isolation (PVI) on cardiac function in patients with paroxysmal AF and impaired LVEF ... |
7,781 | Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrophic cardiomyopathy. | Paced electrogram fractionation analysis (PEFA) has been assessed for the prediction of sudden cardiac death (SCD) in a large-scale, prospective study of patients with hypertrophic cardiomyopathy (HCM).</AbstractText>We determined the positive predictive value (PPV) of PEFA in relation to other risk factors for SCD and... |
7,782 | Implantable defibrillators and prevention of sudden death in hypertrophic cardiomyopathy. | Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death in young people, including trained athletes. The implantable cardioverter-defibrillator (ICD), although initially designed as a treatment for older patients with coronary artery disease, has more recently proved to be a safe and effectiv... |
7,783 | [Highlights 2007 in hospital-based internal medicine: the point of view from the chief residents]. | In 2007, several international studies brought useful information for the daily work of internists in hospital settings. This summary is of course subjective but reflects the interests and questions of the chief residents of the Department of internal medicine who wrote this article like an original trip in medical lit... |
7,784 | Electrocardiographic evaluation of cardiovascular status. | The electrocardiogram (ECG) is indispensable for the diagnosis and management of patients with a wide variety of cardiac and noncardiac diseases. The purpose of this paper is focused on recent research that used ECG, specifically the long-QT interval and microvolt T wave alternans, for the evaluation of life-threatenin... |
7,785 | Clinical and molecular genetics of the short QT syndrome. | Sudden cardiac death in patients without structural heart disease remains a challenge in diagnostics and risk stratification. Genetically determined arrhythmias are a potential cause for a primary electrical disease. A recently discovered primary electrical disease is discussed.</AbstractText>The inherited short QT syn... |
7,786 | Simultaneous right atrioventricular pacing: a novel model to study atrial remodeling and fibrillation in the setting of heart failure. | Atrial fibrillation (AF) is a common arrhythmia which contributes to morbidity and mortality in patients with heart failure (HF). Atrial remodeling is a key substrate for the development of AF in HF. However, experimental models that study AF in the setting of HF have important limitations. We evaluated a new dog model... |
7,787 | The prediction of ICD therapy in multicenter automatic defibrillator implantation trial (MADIT) II like patients: a retrospective analysis. | MADIT II like patients have not been compared to patients without an electrophysiological study, patients in whom ventricular tachycardia or fibrillation were induced in an electrophysiological study (EPS) and patients without an inducibility in EPS in one study.</AbstractText>The multicenter automatic defibrillator im... |
7,788 | Cardiac arrests in hemodialysis patients: An ongoing challenge. | Hemodialysis patients have significant cardiac-related mortality. Sudden cardiac arrests in the dialysis unit are infrequent events but carry a poor prognosis. The predominant rhythm is ventricular tachycardia/fibrillation. Although the exact etiologies are not clear, several studies have confirmed an increased inciden... |
7,789 | Successful outcome utilizing hypothermia after cardiac arrest in pregnancy: a case report. | To date, pregnancy has been considered a contraindication to the use of therapeutic hypothermia after cardiac arrest.</AbstractText>We present the case of a 35-yr-old woman, 13 wks pregnant, who had a witnessed out-of-hospital ventricular fibrillation cardiac arrest. She was resuscitated by prehospital personnel yet re... |
7,790 | Ventricular fibrillation during colonoscopy: a case report--colonoscopy in high-risk patients should be performed with ECG monitoring. | While ventricular premature contractions have been noted during colonoscopy (CS), ventricular fibrillation (VF) is rare. We recently had a patient who developed VF during CS and recovered without any sequelae despite severe complications after cardiopulmonary resuscitation (CPR). If electrocardiogram (ECG) monitoring h... |
7,791 | Subcutaneous array with active can implantable cardioverter defibrillator configuration: a follow-up study. | Novel nontransvenous implantable cardioverter defibrillator (ICD) configurations are sometimes required for small children and children with complex congenital heart disease at risk for sudden death. Mid- to long-term follow-up of these nontraditional implant techniques is not well known. We assessed the mid-term perfo... |
7,792 | Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation. | Antiarrhythmic drug therapy remains the principal approach for suppression of atrial fibrillation (AF) and flutter (AFl) and prevention of their recurrence. Among the current strategies for suppression of AF/AFl is the development of antiarrhythmic agents that preferentially affect atrial, rather than ventricular elect... |
7,793 | Anesthetic preconditioning decreases arrhythmias and improves regional conduction in isolated hearts. | Anesthetic preconditioning (APC) is known to protect the heart against necrosis and contractile dysfunction, but protection against arrhythmias has not been well characterized. The authors hypothesized that APC alters the dispersion of electrophysiologic parameters to reduce arrhythmias after global (G) or regional (R)... |
7,794 | The role of mechanoelectric feedback in vulnerability to electric shock. | Experimental and clinical studies have shown that ventricular dilatation is associated with increased arrhythmogenesis and elevated defibrillation threshold; however, the underlying mechanisms remain poorly understood. The goal of the present study was to test the hypothesis that (1) stretch-activated channel (SAC) rec... |
7,795 | Cardiac effects of electrical stun guns: does position of barbs contact make a difference? | The use of electrical stun guns has been rising among law enforcement authorities for subduing violent subjects. Multiple reports have raised concerns over their safety. The cardiovascular safety profile of these devices in relationship to the position of delivery on the torso has not been well studied.</AbstractText>W... |
7,796 | Evaluation of a novel ventricular support device with defibrillation capabilities in canine and porcine animal models. | Sudden death is prevalent in heart failure patients. We tested an implantable ventricular support device consisting of a wireform harness with one or two pairs of integrated defibrillation electrode coils.</AbstractText>The device was implanted into six pigs (36-44 kg) through a subxiphoid incision. Peak voltage (V) de... |
7,797 | Implications of obstructive sleep apnea for atrial fibrillation and sudden cardiac death. | Obstructive sleep apnea (OSA) is a sleep-related breathing disorder with important cardiovascular consequences, including arrhythmogenesis. The unique pathophysiology of OSA results in multiple intermediate mechanisms that may promote atrial fibrillation, ventricular arrhythmias, and sudden cardiac death. These mechani... |
7,798 | Preoperative alterations in correlation properties and complexity of R-R interval dynamics predict the risk of atrial fibrillation after coronary artery bypass grafting in patients with preserved left ventricular function. | We evaluated whether there are constant preoperative alterations in nonlinear R-R interval dynamics that associate with the risk of postoperative atrial fibrillation in patients with preserved left ventricular function.</AbstractText>We analyzed mean normal-to-normal R-R intervals, short-term scaling exponent of detren... |
7,799 | Myocardial gap junctions: targets for novel approaches in the prevention of life-threatening cardiac arrhythmias. | Direct cell-to-cell communication in the heart is maintained via gap junction channels composed of proteins termed connexins. Connexin channels ensure molecular and electrical signals propagation and hence are crucial in myocardial synchronization and heart function. Disease-induced gap junctions remodeling and/or an i... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.