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7,800 | Aged male and female spontaneously hypertensive rats benefit from n-3 polyunsaturated fatty acids supplementation. | Hypertension-induced myocardial metabolic, structural and electrophysiological remodeling deteriorates with aging and contributes to both heart failure and occurrence of malignant arrhythmias. It has been shown in clinical trials that n-3 polyunsaturated fatty acids (n-3 PUFA) reduce the incidence of cardiovascular dis... |
7,801 | Thyroid hormones modulate occurrence and termination of ventricular fibrillation by both long-term and acute actions. | Thyroid hormones (TH) are powerful modulators of heart function, but their arrhythmogenic effects are less elucidated. We have examined both acute and long-term action of TH on the heart susceptibility to the ventricular fibrillation (VF) and on the heart ability to terminate VF and restore a sinus rhythm. Triiodothyro... |
7,802 | Apical hypertrophic cardiomyopathy might lead to misdiagnosis of ischaemic heart disease. | In this study, demographic, clinic, electrocardiographic and angiographic properties of patients, on whom coronary angiography was performed with the pre-diagnosis of coronary artery disease (CAD) and whose ventriculography demonstrated typical apical hypertrophic cardiomyopathy (AHCM), were investigated.</AbstractText... |
7,803 | Diagnostic value of stored electrograms in pacemaker patients. | Stored electrograms (EGMs) are diagnostic tools in modern pacemakers, providing data concerning arrhythmia occurrence and device function. We sought to validate the impact of stored EGMs on diagnosis and verification of arrhythmias presented after pacemaker implantation.</AbstractText>We enrolled 71 consecutive patient... |
7,804 | Appropriate and inappropriate implantable cardioverter defibrillator interventions during secondary prevention. | ICD therapy is established therapy for secondary prevention after aborted sudden death or ventricular tachycardia. Long-term data on the incidence of appropriate and inappropriate interventions are scarce.</AbstractText>We retrospectively studied 391 patients with an ICD for secondary prophylaxis: 247 (63%) with ischae... |
7,805 | QT and TdP. QT: an unreliable predictor of proarrhythmia. | When triangulation, reverse use dependence, instability and dispersion (TRIaD) of the action potential are associated with drug-induced prolongation of the QT interval, then proarrhythmia in the form of torsade de pointes is most likely. However, as the QT interval is shortened, TRIaD increasingly leads to ventricular ... |
7,806 | An update on cardioembolic stroke. | About one-fifth of all ischaemic strokes are cardioembolic. Recent years have seen considerable progress in our understanding of atrial fibrillation, the most important cause of cardioembolism, and evidence-based treatment strategies have emerged. Progress in relation to other cardioembolic disorders has been more limi... |
7,807 | Effect of drugs on defibrillation capacity. | Over 300,000 people die of sudden cardiac death (SCD) in the US annually. Implantable cardioverter-defibrillators (ICDs) have been shown to be more effective than antiarrhythmic drugs for the prevention of SCD in specific susceptible populations. Many patients in whom ICDs have been implanted receive concomitant therap... |
7,808 | WPW and preexcitation syndromes. | Wolff-Parkinson-White syndrome is a disorder characterized by presence of an accessory pathway which predisposes patients to tachyarrhythmias and sudden death. Among patients with WPW syndrome, atrioventricular reentrant tachycardia (AVRT) is the most common arrhythmia, accounting for 95% of re-entrant tachycardias. It... |
7,809 | Sudden cardiac death complicating newly diagnosed atrial fibrillation in the setting of subclinical hyperthyroidism. | Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and a predictor of all-cause mortality. Subclinical hyperthyroidism is an independent risk factor for developing AF but its clinical significance in younger patients has not been established. We describe a clinical case of a 44-year-old female ... |
7,810 | Propofol infusion syndrome: an overview of a perplexing disease. | Propofol (2, 6-diisopropylphenol) is a potent intravenous hypnotic agent that is widely used in adults and children for sedation and the induction and maintenance of anaesthesia. Propofol has gained popularity for its rapid onset and rapid recovery even after prolonged use, and for the neuroprotection conferred. Howeve... |
7,811 | Long-term follow-up of patients treated with ICD: benefit in patients with preserved left ventricular function. | Most major defibrillator trials have short follow-up and may neither capture the benefit for those with preserved function nor the progressive nature of advanced heart disease. We intended to investigate the long-term outcome in an unselected population of patients treated with ICD.</AbstractText>We followed 124 consec... |
7,812 | [Specific bradycardic drug zatebradin: cardiac rhythm variability, antifibrillatory, and antiischemic effects]. | The results of experiments on narcotized cats and rats showed that the drug zatebradin produces a specific bradycardic action by reducing the heart rate and the double product, while virtually not influencing vitally important parameters of the heart activity such as the cardiac output and the mean acceleration of the ... |
7,813 | The prevalence of supraventricular arrhythmias with regard to the type and degree of left ventricular hypertrophy in patients with hypertensive heart disease. | We investigated the correlation between the type and degree of left ventricular hypertrophy and the prevalence of supraventricular arrhythmias in patients with hypertensive heart disease.</AbstractText>The study included 179 patients (79 men, 100 women, aged 43-80 years, median 68 years) with left ventricular hypertrop... |
7,814 | [Drug induced QT prolongation]. | Prolongation of the ventricular repolarisation manifests itself as a prolongation of the QT intervall on the surface ECG and represents a major risk for a special form of ventricular tachycardia called "torsades de pointes". Torsades de pointes are often self limited and are associated with palpitations, dizziness or s... |
7,815 | [Effect of streptomycin on stretch-induced change in myocardial activation during ventricular fibrillation]. | The aim of this study was to determine whether the changes in myocardial activation pattern resulting from acute stretching during ventricular fibrillation can be counteracted by administering a compound that blocks receptors sensitive to stretch. The study involved 16 isolated rabbit hearts, in which refractoriness an... |
7,816 | [Non-invasive characterization of atrial activity immediately prior to termination of paroxysmal atrial fibrillation (corrected)]. | Atrial activity characterization with a high degree of detail can be reached by analyzing invasive recordings. Nevertheless, electrocardiographic signal processing tools can nowadays obtain equivalent information in some cases. The aim of this work is to study the electrocardiographic alterations produced during the la... |
7,817 | The proarrhythmic effect of incomplete pulmotricuspid isthmus ablation in a patient with sarcoid-related ventricular tachycardia? | Proarrhythmia is relatively common after extensive atrial ablation for atrial fibrillation, but has not been frequently documented after catheter ablation of ventricular tachycardia (VT). In theory, this phenomenon could occur if an incomplete ablation line is created between two nonconducting structures, such as dense... |
7,818 | Clinical profile, prognosis and treatment of patients with infective endocarditis--a 14-year follow-up study. | Poor prognosis of infective endocarditis (IE) is not only attributable to high morbidity and mortality during an active phase of the disease, but also to late complications and relapses occurring after eradication of the infection. Identification of unfavorable prognostic factors allows to optimize therapeutic modaliti... |
7,819 | Signal-averaged P-wave ECG as a marker of atrial electrical instability in patients with right ventricular dysfunction. | Severe pulmonary hypertension (PAH) leads to right ventricular dysfunction and is associated with different atrial arrhythmias. In PAH patients, the echocardiographic Tei-index is used for monitoring right heart function. The P-wave signal-averaged ECG (SA-ECG) has been shown to have a potential role in identifying pat... |
7,820 | Cibenzoline intoxication: effect of combined hemoperfusion-hemodialysis on plasma clearance. | Cibenzoline is an antiarrhythmic drug used to treat patients with supraventricular or ventricular arrhythmias. Cibenzoline overdose is associated with proarrhythmic and hemodynamic effects such as hypotension and congestive heart failure.</AbstractText>We report a case of cardiogenic shock due to cibenzoline overdose i... |
7,821 | Regenerative therapies in electrophysiology and pacing. | The prevention and treatment of cardiac arrhythmias conferring major morbidity and mortality is far from optimal, and relies heavily on devices and drugs for the partial successes that have been seen. The greatest success has been in the use of electronic pacemakers to drive the hearts of patients having high degree he... |
7,822 | Inappropriate analyses of automated external defibrillators used during in-hospital ventricular fibrillation. | The use of automated external defibrillators (AEDs) has increased the number of survivors of out-of-hospital cardiac arrest. The AED has a high specificity and moderately high sensitivity in detecting rhythms appropriately treated by defibrillation. However, a few shockable rhythms are misdiagnosed by the AED. Two case... |
7,823 | Atria are more susceptible to electroporation than ventricles: implications for atrial stunning, shock-induced arrhythmia and defibrillation failure. | Defibrillation shock is known to induce atrial stunning, which is electrical and mechanical dysfunction.</AbstractText>We hypothesized that atrial stunning is caused by higher atrial susceptibility to electroporation vs ventricles. We also hypothesize that electroporation may be responsible for early recurrence of atri... |
7,824 | Excito-oscillatory dynamics as a mechanism of ventricular fibrillation. | The instabilities associated with reentrant spiral waves are of paramount importance to the initiation and maintenance of tachyarrhythmias, especially ventricular fibrillation (VF). In addition to tissue heterogeneities, there are only a few basic purported mechanisms of spiral wave breakup, most notably restitution.</... |
7,825 | Association between statin use and mortality in patients with implantable cardioverter-defibrillators and left ventricular systolic dysfunction. | A few previous nested cohort trials have evaluated the use of statins on survival and the occurrence of ventricular tachycardia or fibrillation (VT/VF). While the studies generally agreed on the survival effects, they disagreed on the magnitude of the mortality benefit and on the effect on VT/VF.</AbstractText>The purp... |
7,826 | The role of fish oil in arrhythmia prevention. | Numerous epidemiological studies, case-control series, and randomized trials have demonstrated the ability of fish oil to reduce major cardiovascular events, particularly sudden cardiac death and all-cause mortality. We discuss the potential benefits of fish oil therapy to improve overall autonomic tone and potentially... |
7,827 | Effect on treatment delay of prehospital teletransmission of 12-lead electrocardiogram to a cardiologist for immediate triage and direct referral of patients with ST-segment elevation acute myocardial infarction to primary percutaneous coronary intervention. | Prehospital electrocardiogram (ECG) transmission to hospitals was shown to reduce time to treatment in patients with acute myocardial infarction. However, new technologies allow transmission directly to a mobile unit so an attending physician can respond irrespective of presence within or outside the hospital. The prim... |
7,828 | Myocardial cytokine IL-8 and nitric oxide synthase activity during and after resuscitation: preliminary observations in regards to post-resuscitation myocardial dysfunction. | Increases in serum cytokines have been reported after successful resuscitation from prolonged ventricular fibrillation (VF). Pro-inflammatory cytokines can stimulate inducible nitric oxide synthase (iNOS) to produce excessive levels of nitric oxide (NO). High levels of both myocardial inflammatory cytokines and nitric ... |
7,829 | Mechanical modulation of atrial flutter cycle length. | Although atrial flutter (AFL) is considered a highly regular rhythm, small fluctuations in cycle length have been described. The mechanisms responsible for these interval oscillations have been investigated by recent studies in humans which have shown that cyclic variations in atrial volume and pressure following ventr... |
7,830 | Headache angina. | The initial recognition of acute myocardial infarction at the time of the emergency department (ED) visit may be difficult in the absence of typical presentations such as chest pain, diaphoresis, and radiation tenderness. Headache angina, although reported in several instances in the past with variable patient outcomes... |
7,831 | Double-dose external cardioversion for refractory unstable atrial fibrillation in the ED. | A 45-year-old man with dilated cardiomyopathy, atrial fibrillation, and hypertension presented to the emergency department with palpitations and shortness of breath for 2 days after running out of his medications. An electrocardiogram disclosed atrial fibrillation with rapid ventricular response. The patient was hemody... |
7,832 | Efficacy of transesophageal defibrillation in ventricular fibrillation of long duration. | Increasing duration of ventricular fibrillation (VF) is associated with a higher risk of ineffective resuscitation. In addition, precountershock chest compression can influence defibrillation success. Transesophageal defibrillation may increase defibrillation success because of the proximity of the esophagus to the hea... |
7,833 | The role of concomitant arrhythmia surgery in patients undergoing repair of congenital heart disease. | Long-term survival after repair of complex congenital heart lesions is associated with the late development of arrhythmias as well as residual hemodynamic abnormalities. Understanding arrhythmias as electromechanical problems provides the basis for surgical intervention to correct the arrhythmia as well as anatomical d... |
7,834 | Antifibrillatory properties of mivacurium in a canine model of atrial fibrillation. | The electrophysiologic actions of the competitive neuromuscular blocker mivacurium (0.05-0.8 mg/kg IV; N = 10) and atropine sulfate [0.01-0.16 mg/Kg intravenously (IV), N = 6] were determined under control conditions, during right vagus nerve stimulation, and during anterior right ganglionated plexus stimulation. Both ... |
7,835 | Piperazine protects the rat heart against sudden cardiac death from barium chloride-induced ventricular fibrillation. | Fifteen of 20 Wistar albino rats were treated with various doses of the anthelmintic agent piperazine citrate (15, 30, and 60 mg/kg body weight). All 20 rats were subsequently given barium chloride, 20 mg/kg. The 5 rats (25%) that did not receive piperazine citrate developed ventricular fibrillations after barium chlor... |
7,836 | Sudden death in an Emery-Dreifuss muscular dystrophy patient with an implantable defibrillator. | We report the first case of witnessed sudden death of an Emery-Dreifuss muscular dystrophy (EDMD) patient with a properly functioning implantable cardioverter-defibrillator (ICD). This 38-yr-old woman with normal left ventricular function had a history of recurrent syncope and nonsustained ventricular tachycardia, for ... |
7,837 | Cardiac resynchronization therapy in patients with heart failure and atrial fibrillation: importance of new-onset atrial fibrillation and total atrial conduction time. | Cardiac resynchronization therapy (CRT) is an established therapy for patients with heart failure and sinus rhythm (SR), but its value in atrial fibrillation (AF) remains unclear. Furthermore, response to CRT may be difficult to predict in these patients. The aim of our study was to investigate whether predictors for C... |
7,838 | Atrial fibrillation in patients with Brugada syndrome relationships of gene mutation, electrophysiology, and clinical backgrounds. | The goal of our work was to examine the relationships of atrial fibrillation (AF) with genetic, clinical, and electrophysiological backgrounds in Brugada syndrome (BrS).</AbstractText>Atrial fibrillation is often observed in patients with BrS and indicates that electrical abnormality might exist in the atrium as well a... |
7,839 | Ventricular repolarization restitution properties in patients exhibiting type 1 Brugada electrocardiogram with and without inducible ventricular fibrillation. | This study aimed to elucidate the contribution of the repolarization restitution property to the sustained ventricular fibrillation (VF) in Brugada syndrome.</AbstractText>Although phase 2 re-entry develops as the trigger of VF, the other precipitating factors have remained unclear.</AbstractText>Twenty-one patients wi... |
7,840 | Atrial fibrillation and Brugada syndrome. | Brugada syndrome is characterized by right bundle branch block pattern with ST-segment elevation in leads V(1) to V(3) and a propensity for sudden cardiac death due to ventricular arrhythmias. The arrhythmogenic substrate in Brugada syndrome may not be restricted to the ventricles, and atrial arrhythmias are being incr... |
7,841 | Early and late survival after surgical revascularization for ischemic ventricular fibrillation/tachycardia. | Ischemic ventricular fibrillation/tachycardia (VF/VT) treated by myocardial revascularization, often with an implanted cardioverter defibrillator, prevents sudden cardiac death. Early series have suggested that recurrent VF/VT threatens survival even after treatment. As late outcome is unknown, we sought to determine i... |
7,842 | [Arrhythmias in patients with obstructive sleep apnea]. | The authors summarize the current knowledge on the types, prevalence, reasons, diagnosis and current therapy of arrhythmias occurring in patients with obstructive sleep apnea. Most of the patients with obstructive sleep apnea have nocturnal bradycardia (5-50%), paroxysmal tachyarrhythmia (atrial 35%; ventricular 0-15%)... |
7,843 | Chronic heart failure, selected risk factors and co-morbidities among adults treated for hypertension in a cardiac referral hospital in Cameroon. | Information on clinical characteristics of heart failure (HF) among Africans with hypertension is needed to help define the burden of hypertension in this population, but currently there is little data available.</AbstractText>To determine the clinical characteristics of HF, related risk factors and co-morbidities amon... |
7,844 | Overexpression of junctate induces cardiac hypertrophy and arrhythmia via altered calcium handling. | Junctate-1 is a newly identified integral endoplasmic/sarcoplasmic reticulum Ca2+ binding protein. However, its functional role in the heart is unknown. In the present study, the consequences of constitutively overexpressed junctate in cardiomyocytes were investigated using transgenic (TG) mice overexpressing junctate-... |
7,845 | Electromagnetic interference produced by a hearing aid device on electrocardiogram recording. | An 85-year-old male was implanted with a single-chamber permanent pacemaker because of atrial fibrillation with slow ventricular response. The patient had a chronic hearing impairment and decided to buy a hearing aid device. The MyLink device (MyLink, Phonak, Stafa, Switzerland) is a multifrequency FM transmitter/recei... |
7,846 | The current prevalence of sleep disordered breathing in congestive heart failure patients treated with beta-blockers. | Although sleep disordered breathing is thought to be common in patients with systolic heart failure, prior studies are difficult to interpret due to a variety of factors including small sample sizes, referral bias to sleep laboratories among participants, lack of modern medical therapy for congestive heart failure, and... |
7,847 | Ablation of atrial fibrillation in patients with heart failure: reversal of atrial and ventricular remodelling. | The management of patients with heart failure and atrial fibrillation (AF) is a medical challenge, especially in the case of patients in whom sinus rhythm or rate control cannot be achieved with optimal pharmaceutical treatment.</AbstractText>Thirteen consecutive patients (11 men and 2 women, 35-70 years old, median ag... |
7,848 | Effects of chronic exercise on myocardial refractoriness: a study on isolated rabbit heart. | To determine whether chronic physical training increases atrial and ventricular refractoriness in isolated rabbit heart.</AbstractText>Trained rabbits were submitted to a protocol of treadmill running. The electrophysiological parameters of refractoriness investigated in an isolated heart preparation were: (1) atrial e... |
7,849 | [Vasopressin for treatment of hemodynamic disorders]. | Vasopressin is a 9-amino acid peptide synthesized by magnocellular neurons of the hypothalamus and released from posterior pituitary gland. The primary physiological role of vasopressin is the maintenance of fluid homeostasis. In this review, the classification of vasopressin receptors, namely V1 vascular, V2 renal, V3... |
7,850 | [Right ventricular desynchronization in patients with pacemaker syndrome]. | To observe the incidence of ventricular desynchronization in patients with or without pacemaker syndrome (PMS).</AbstractText>The systolic peak velocity, the acceleration and the time to peak velocity of the interventricular septum (IVS), left ventricular (LV) and right ventricular (RV) lateral wall were detected by ti... |
7,851 | [Factors associated with efficacy of cardiac resynchronization therapy for patients with congestive heart failure]. | The efficacy of cardiac resynchronization therapy (CRT) in patients with congestive heart failure and the potential factors associated with responder or nonresponder were investigated.</AbstractText>Fifty three patients with congestive heart failure (42 with sinus rhythm and 11 with atrial fibrillation) underwent CRT w... |
7,852 | [Efficacy of cardiac resynchronization therapy-defibrillator for treating patients with chronic heart disease]. | To observed the clinical efficacy of cardiac resynchronization therapy-defibrillator (CRT-D) in selected patients with chronic heart failure one year after implantation.</AbstractText>Seventeen patients with drug-refractory heart failure received CRT-D implantation (6 patients were implanted with InSync Sentry). The un... |
7,853 | A case of appropriate inappropriate device therapy: hyperkalemia-induced ventricular oversensing. | The present case describes a patient who received inappropriate, but potentially life-saving, therapy from her implantable cardioverter defibrillator (ICD) in the setting of acute hyperkalemia (plasma potassium concentration = 8 mM). Hyperkalemia was associated with the development of a slow sinusoidal ventricular tach... |
7,854 | Influence of atrial fibrillation on plasma von willebrand factor, soluble E-selectin, and N-terminal pro B-type natriuretic peptide levels in systolic heart failure. | Endothelial dysfunction is present in patients with heart failure (HF) due to left ventricular systolic dysfunction, as well as in patients with atrial fibrillation (AF) who have normal cardiac function. It is unknown whether AF influences the degree of endothelial dysfunction in patients with systolic HF.</AbstractTex... |
7,855 | Vasopressin and epinephrine in the treatment of cardiac arrest: an experimental study. | Epinephrine remains the drug of choice for cardiopulmonary resuscitation. The aim of the present study is to assess whether the combination of vasopressin and epinephrine, given their different mechanisms of action, provides better results than epinephrine alone in cardiopulmonary resuscitation.</AbstractText>Ventricul... |
7,856 | A fatal case of venlafaxine overdose. | Based on its primary action of serotonin reuptake inhibition, venlafaxine overdose would be expected to result in serotonergic effects.</AbstractText>A 40 year old male ingested venlafaxine without co-ingestants in a suicide attempt. The patient developed refractory ventricular fibrillation and expired approximately 9 ... |
7,857 | [Predictive value of NT-pro-BNP for the non-cardiologist. A study on 573 hospitalized patients with cardiovascular disease]. | B-type natriuretic peptides are excellent markers of cardiac function and are strong prognostic parameters in patients with coronary heart disease and heart failure. We examined the diagnostic and prognostic value of natriuretic peptides in a heterogeneous group of patients of a cardiological university hospital.</Abst... |
7,858 | Impact of acute renal failure following percutaneous coronary intervention on long-term mortality. | Acute renal failure (ARF) following percutaneous coronary intervention (PCI) has been shown to be associated with a worse outcome. Whether this event should be considered as a marker of disease severity or an independent contributor to mortality is still unclear.</AbstractText>In a multicenter, prospective cohort study... |
7,859 | Minimally interrupted cardiac resuscitation by emergency medical services for out-of-hospital cardiac arrest. | Out-of-hospital cardiac arrest is a major public health problem.</AbstractText>To investigate whether the survival of patients with out-of-hospital cardiac arrest would improve with minimally interrupted cardiac resuscitation (MICR), an alternate emergency medical services (EMS) protocol.</AbstractText><AbstractText La... |
7,860 | A detector for a chronic implantable atrial tachyarrhythmia monitor. | Continuous long-term monitoring of atrial fibrillation (AF) and tachycardia (AT) is an unmet clinical need, which could be met with a chronically-implanted monitor. Improved therapeutic decisions based on accurate monitoring of parameters, such as daily AF/AT burden (hours/ day) may lead to improvements in clinical out... |
7,861 | Ranolazine: a new antiarrhythmic agent for patients with non-ST-segment elevation acute coronary syndromes? | Ranolazine is a novel antianginal agent that has also been shown to have electrophysiological properties in laboratory models. This is the first clinical evaluation of the antiarrythmic effects of ranolazine.</AbstractText>To compare the incidence of cardiac arrhythmias in patients with non-ST-segment elevation acute c... |
7,862 | MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. | We identified a novel muscle-restricted putative coiled-coil protein, MURC, which is evolutionarily conserved from frog to human. MURC was localized to the cytoplasm with accumulation in the Z-line of the sarcomere in the murine adult heart. MURC mRNA expression in the heart increased during the developmental process f... |
7,863 | BNP and NT-proBNP predict echocardiographic severity of diastolic dysfunction. | To evaluate the best combination of clinical parameters and brain natriuretic peptide (BNP) or N-terminal pro-BNP (NT-proBNP), to predict diastolic dysfunction (DD) in heart failure with preserved left ventricular ejection fraction (HF-PLEF) as determined by Doppler-echocardiography.</AbstractText>HF patients with EF &... |
7,864 | New concepts in understanding and modulating atrial repolarisation in patients with atrial fibrillation. | Atrial fibrillation is the most frequent cardiac arrhythmia in clinical practice. Although much has been learned, the underlying mechanisms are incompletely understood. Clinically used antiarrhythmic drugs are limited in their efficacy to terminate atrial fibrillation or to maintain sinus rhythm and were associated wit... |
7,865 | [Avoidance of ventricular pacing in patients with sinus node disease or intermittent AV block]. | In patients with frequent right ventricular stimulation, worsening of heart failure and atrial fibrillation may occur. Avoidance of unnecessary right ventricular pacing is a major requirement for pacemaker selection and programming in patients with sinus node disease or intermittent AV block. In dual chamber pacemakers... |
7,866 | Electrical restitution determined by epicardial contact mapping and surface electrocardiogram: its role in ventricular fibrillation inducibility in swine. | The roles of electrical restitution determined by epicardial contact mapping and surface electrocardiogram (ECG) in the inducibility of ventricular fibrillation (VF) were evaluated.</AbstractText>Ten epicardial unipolar electrograms using contact mapping and the surface ECGs were simultaneously recorded in 7 swine. Act... |
7,867 | Antiarrhythmic effects of growth hormone--in vivo evidence from small-animal models of acute myocardial infarction and invasive electrophysiology. | A growing body of evidence suggests a possible role for growth hormone (GH) in the treatment of congestive heart failure (CHF) and myocardial infarction (MI). The aim of this study was to investigate in vivo the effects of GH treatment on incidence and severity of ventricular arrhythmias normal and MI rats.</AbstractTe... |
7,868 | Persistent atrial fibrillation worsens heart rate variability, activity and heart rate, as shown by a continuous monitoring by implantable biventricular pacemakers in heart failure patients. | Atrial fibrillation (AF) induces loss of atrial contribution, heart rate irregularity, and fast ventricular rate.</AbstractText>The objectives of the study were to accurately measure AF incidence and to investigate the mutual temporal patterns of AF and heart failure (HF) in patients indicated to cardiac resynchronizat... |
7,869 | The role of surface ECG and transthoracic echocardiography for predicting postoperative atrial fibrillation after coronary artery bypass surgery. | To evaluate the roles of surface electrocardiogram (ECG) and transthoracic echocardiography (ECHO) for prediction of atrial fibrillation (AF) after coronary artery bypass grafting (CABG).</AbstractText>This study was conducted from 2002-2004 at the Cardiovascular Department of Hacettepe University, Ankara, Turkey. Seve... |
7,870 | Association between hypertensive urgencies and subsequent cardiovascular events in patients with hypertension. | To determine whether patients with hypertensive urgency have a higher risk for subsequent cardiovascular events compared with hypertensive patients without this event.</AbstractText>Overall, 384 patients with hypertensive urgency and 295 control patients were followed up for at least 2 years. Hypertensive urgency was d... |
7,871 | Pericardial delivery of omega-3 fatty acid: a novel approach to reducing myocardial infarct sizes and arrhythmias. | Basic and clinical evidence suggests that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) decrease fatal arrhythmias and infarct sizes. This study investigated if pericardial delivery of n-3 PUFAs would protect the myocardium from ischemic damages and arrhythmias. Acute myocardial infarctions were induced in 23 pigs ... |
7,872 | [Differential diagnosis in patients with suspected anoxic-ischaemic coma]. | Three case studies illustrate that suspected anoxic-ischaemic coma often requires careful differential diagnosis to detect treatable conditions. A 47-year-old man underwent cardiopulmonary resuscitation for ventricular fibrillation caused by myocardial ischaemia. He exhibited rhythmic eyelid movements while in a coma. ... |
7,873 | [Nibentan in arresting acute atrial fibrillation: risk or benefit?]. | To study efficacy and safety of using a domestic anti-arrhythmic drug nibentan for arresting acute atrial fibrillation.</AbstractText>A total of 210 patients received nibentan in a dose 0.125 mg/kg dissolved in 20.0 ml of 0.9% sodium chloride solution by intravenous slow jet 3-min injection. In no response, the injecti... |
7,874 | Prediction of successful defibrillation in human victims of out-of-hospital cardiac arrest: a retrospective electrocardiographic analysis. | In the present study we sought to examine the efficacy of an electrocardiographic parameter, 'amplitude spectrum area' (AMSA), to predict the likelihood that any one electrical shock would restore a perfusing rhythm during cardiopulmonary resuscitation in human victims of out-of-hospital cardiac arrest. AMSA analysis i... |
7,875 | Treatment options for patients with coronary artery disease identified as high risk by T-wave alternans testing. | Risk stratification for primary prevention of sudden cardiac death (SCD) remains a major challenge in cardiology. The utility of T-wave alternans (TWA) as a marker of risk of life-threatening ventricular tachycardia and fibrillation is supported by two decades of basic and clinical research. Both frequency- and time-do... |
7,876 | Medium- and long-term survival after pacemaker implant: Improved survival with right ventricular outflow tract pacing. | Long-term prognosis after pacemaker implant depends on numerous variables, particularly structural heart disease. There is evidence that apical stimulation could favor the development of heart failure and, therefore, influence mortality. Other right ventricular pacing sites have been studied, for example the outflow tr... |
7,877 | [Surgical cryoablation and left ventriculoplasty for electrical storm after acute myocardial infarction]. | A 65-year-old man was referred to our hospital to treat recent anterior myocardial infarction. Coronary artery angiography showed acute occlusion of left anterior descending coronary artery (LAD) and chronic occlusion of right coronary artery. After emergent percutaneous coronary intervention for LAD, drug-refractory e... |
7,878 | Regulatory mechanisms of atrial fibrotic remodeling in atrial fibrillation. | Electrical, contractile and structural remodeling have been characterized in atrial fibrillation (AF), and the latter is considered to be the major contributor to AF persistence. Recent data show that interstitial fibrosis can predispose to atrial conduction impairment and AF induction. The interplay between cardiac ma... |
7,879 | Electrocardiographic abnormalities in patients with heart failure. | The morbidity and mortality from heart failure (HF) differ between patients with reduced (< 50%) and with preserved ( >or= 50%) left ventricular ejection fraction (LVEF) on account of many factors, including abnormalities detected in the electrocardiogram (ECG). The aim of this study was to determine and compare ... |
7,880 | Postaortic valve replacement bradycardia induced torsades de pointes. | The authors present an unusual case of torsades de pointes (Tdp) in an elderly woman with a history of aortic stenosis, status post aortic valve replacement. She was admitted for atrial fibrillation with a slow ventricular response. At the time of admission, the patient was asymptomatic and not taking any medications k... |
7,881 | Echocardiographic parameters and all-cause mortality: the Rotterdam Study. | Even when heart failure has not yet become clinically manifest, preclinical ventricular dysfunction may be present, and therapeutic interventions introduced at this time may reduce morbidity and mortality. However, data on the predictive value of echocardiographic characteristics in the general population remain relati... |
7,882 | Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure. | The peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activator pioglitazone antagonizes angiotensin II actions and possesses anti-inflammatory and antioxidant properties in vitro. There is evidence that pioglitazone improves ventricular remodeling in some experimental models.</AbstractText>The purpose of t... |
7,883 | Optimization of superior vena cava coil position and usage for transvenous defibrillation. | Prior studies of active pectoral implantable defibrillator (ICD) lead systems demonstrated a lowering of defibrillation thresholds (DFTs) with the addition of a superior vena cava (SVC) coil. These studies were done on fixed-tilt waveforms where a large reduction in impedance leads to large phase duration changes.</Abs... |
7,884 | Mitral valve surgery in emergency for severe acute regurgitation: analysis of postoperative results from a multicentre study. | To evaluate postoperative outcome of emergency surgery for acute severe mitral regurgitation (ASMR) from a multicentre experience.</AbstractText>In six centres, 279 patients (mean age 62+/-14 years, 62% female) undergoing emergency surgery for ASMR from December 1986 to March 2007 were analysed and followed up. Aetiolo... |
7,885 | Anticoagulants, antiplatelets, and statins in heart failure. | The existing guidelines for the treatment of patients who have heart failure limit the administration of antiplatelet and anticoagulant agents to patients who have specific comorbidities, including coronary artery disease, atrial fibrillation, history of thromboembolic events, and left ventricular mural thrombus. Retro... |
7,886 | Sudden cardiac arrest in hypertrophic cardiomyopathy in the absence of conventional criteria for high risk status. | Two patients with hypertrophic cardiomyopathy are reported from the recent experience of the Hypertrophic Cardiomyopathy Center of the Minneapolis Heart Institute Foundation, demonstrating limitations in the risk stratification algorithm currently used for this disease. One patient, an asymptomatic 21-year-old male col... |
7,887 | Meta-analysis comparing reported frequency of atrial fibrillation after acute coronary syndromes in Asians versus whites. | The development of atrial fibrillation (AF) in cardiac patients is multifactorial, including not well defined genetic factors. To determine if Asian ethnicity is associated with the development of AF in patients with coronary disease, a meta-analysis was conducted of patient-level data from 7 prospective randomized cli... |
7,888 | Mild hypothermia during advanced life support: a preliminary study in out-of-hospital cardiac arrest. | Induction of mild hypothermia after cardiac arrest may confer neuroprotection. We assessed the feasibility, safety and effectiveness of therapeutic infusion of 2 l of normal saline at 4 degrees C before return of spontaneous circulation during cardiopulmonary resuscitation after out of hospital cardiac arrest.</Abstrac... |
7,889 | Moderate hypothermia increases the chance of spiral wave collision in favor of self-termination of ventricular tachycardia/fibrillation. | In cardiac arrest due to ventricular fibrillation (VF), moderate hypothermia (MH, 33 degrees C) has been shown to improve defibrillation success compared with normothermia (NR, 37 degrees C) and severe hypothermia (SH, 30 degrees C). The underlying mechanisms remain unclear. We hypothesized that MH might prevent reentr... |
7,890 | [Trichosporon asahii an emerging etiologic agent of fungal infection and colonization in heart failure patients in intensive care unit: case report and literature review]. | Infection with the non-Candida yeast species Trichosporon have been recognized with increasing frequency over the last two decades. Invasive disease due to trichosporonosis has been reported from neutropenic patients with cancer and the mortality is high. Recently, others groups of patients have become susceptible to t... |
7,891 | Improvement in cardiac sympathetic nerve activity in responders to resynchronization therapy. | To assess changes in cardiac adrenergic activity with cardiac resynchronization therapy (CRT), and to investigate whether these changes are related to improvement in left ventricular ejection fraction (LVEF).</AbstractText>Sixteen patients (13 males, age 66 +/- 7 years) were studied at baseline and after > or =6 mon... |
7,892 | Right ventricular pacing is an independent predictor for ventricular tachycardia/ventricular fibrillation occurrence and heart failure events in patients with an implantable cardioverter-defibrillator. | There is increasing evidence that right ventricular (RV) pacing may have detrimental effects by increasing morbidity and mortality for heart failure in implantable cardioverter-defibrillator (ICD) patients. In this study we prospectively tested the hypothesis that cumulative RV pacing increases ventricular tachycardia/... |
7,893 | High defibrillation energy requirements are encountered rarely with modern dual-chamber implantable cardioverter-defibrillator systems. | Defibrillation conversion testing to assure a 10 J safety margin is a standard practice during implantable cardioverter-defibrillator (ICD) implantation. Little data are available on the number of patients who do not have a 10 J margin initially and therefore require system revisions, further testing, or a higher energ... |
7,894 | Mechanisms for the genesis of paroxysmal atrial fibrillation in the Wolff Parkinson-White syndrome: intrinsic atrial muscle vulnerability vs. electrophysiological properties of the accessory pathway. | Paroxysmal atrial fibrillation (PAF) develops in up to one-third of patients with the Wolff Parkinson-White syndrome (WPW). The reason for this high incidence of PAF in the WPW syndrome is not yet clearly understood. When PAF appears in patients with WPW syndrome who have anterograde conduction via the accessory pathwa... |
7,895 | Association of body weight with total mortality and with ICD shocks among survivors of ventricular fibrillation in out-of-hospital cardiac arrest. | Studies have shown an association between obesity and total mortality among people with and without coronary artery disease. This study reviews outcomes among obese survivors of ventricular fibrillation in out-of-hospital cardiac arrest.</AbstractText>All survivors of ventricular fibrillation in out-of-hospital cardiac... |
7,896 | A blinded, randomized controlled evaluation of an impedance threshold device during cardiopulmonary resuscitation in swine. | An impedance threshold device (ITD) has been designed to enhance circulation during CPR. A recent study suggests that the ITD does not improve hemodynamics and that it may actually worsen outcomes. We sought to independently assess the effect of the ITD on coronary perfusion pressure (CPP) and passive ventilation (PaCO... |
7,897 | Usefulness of emergency medical teams in sport stadiums. | In August 2006, the new AZ Alkmaar soccer stadium (capacity 17,000) opened. To provide adequate emergency support, medical teams of Red Cross volunteers and coronary care unit and emergency room nurses were formed, and facilities including automated external defibrillators were made available at the stadium. During eve... |
7,898 | Predictors of atrial arrhythmias after device closure of secundum type atrial septal defects in adults. | Atrial tachyarrhythmias (ATs) contribute substantially to morbidity in adult patients with secundum atrial septal defects (ASDs). The purpose of this study was to prospectively determine the incidence of AT in adults with an ASD and identify predictors of AT occurrence after closure. This was a prospective study of 200... |
7,899 | Atrial fibrillation associated with a thyroid stimulating hormone-secreting adenoma of the pituitary gland leading to a presentation of acute cardiac decompensation: a case report. | Hyperthyroidism is a well established cause of atrial fibrillation (AF). Thyroid Stimulating Hormone-secreting pituitary tumours are rare causes of pituitary hyperthyroidism. Whilst pituitary causes of hyperthyroidism are much less common than primary thyroid pathology, establishing a clear aetiology is critical in min... |
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