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8,000 | [A case report of inoperable gastric cancer demonstrating a clinical CR after chemo-radiation therapy employing weekly DOC]. | A 76-year-old man was admitted to our hospital complaining a weight loss and dysphagia. Gastro-intestinal fiberscopy (GIF) examination showed an early gastric cancer located at cardia. Because of his severe co-morbidities, such as unruptured intracranial aneurysm and idiopathic ventricular fibrillation, he was consider... |
8,001 | First case report in Japan of left ventricular pacing via a coronary vein in a patient with a mechanical tricuspid valve. | Transvenous endocardial pacemaker implantation is contraindicated in patients after prosthetic tricuspid valve replacement. A 65-year-old woman underwent both replacement of the mitral and tricuspid valves and pacemaker implantation with epicardial lead for bradycardia with chronic atrial fibrillation. At 2 years after... |
8,002 | Attenuation of diastolic heart failure and life-threatening ventricular tachyarrhythmia after peripheral blood stem cell transplantation combined with cardioverter-defibrillator implantation in myeloma-associated cardiac amyloidosis. | A patient had multiple myeloma and associated cardiac amyloidosis, which caused diastolic dysfunction and recurrent ventricular fibrillation. After implantation of a cardioverter-defibrillator (ICD), the patient underwent autologous peripheral blood stem cell transplantation (PBSCT). The life-threatening arrhythmias, s... |
8,003 | Inhomogenic effect of bepridil on atrial electrical remodeling in a canine rapid atrial stimulation model. | The antiarrhythmic or reverse remodeling effects of bepridil, a multi-ion channel blocker, have been recently reported, but inhomogeneity of the electrical remodeling and effects of bepridil have been observed in previous reports. In this study, the effect of long-term administration of bepridil on atrial electrical re... |
8,004 | Association of sinus node dysfunction, atrioventricular node conduction abnormality and ventricular arrhythmia in patients with Kawasaki disease and coronary involvement. | This study was performed to investigate the incidence of arrhythmias in patients with Kawasaki disease (KD).</AbstractText>Electrophysiologic studies (EPS) were performed in 40 patients (mean age: 10.3+/-5.1 years; 30 males, 10 females) with KD who had severe to moderate coronary artery disease. Clinical arrhythmias we... |
8,005 | Tunnel propagation of postshock activations as a hypothesis for fibrillation induction and isoelectric window. | Comprehensive understanding of the ventricular response to shocks is the approach most likely to succeed in reducing defibrillation threshold. We propose a new theory of shock-induced arrhythmogenesis that unifies all known aspects of the response of the heart to monophasic (MS) and biphasic (BS) shocks. The central hy... |
8,006 | Fatal amiodarone-induced hepatotoxicity: a case report and literature review. | To report a fatal case of amiodarone-induced acute hepatotoxicity after intravenous amiodarone administration and similar fatal cases review.</AbstractText>A 72-year-old woman with a history of hypertension, prior cardiovascular disease, atrial fibrillation and diabetes mellitus was admitted to the hospital with acute ... |
8,007 | Gender differences in selection of pacemakers: a single-center study. | Previous studies have reported gender differences in pacemaker selection.</AbstractText>This study aimed to assess gender-related differences in pacemaker mode selection in patients undergoing their first implantation.</AbstractText>A retrospective analysis was undertaken from a single-center database of pacemaker impl... |
8,008 | Atrial fibrillation and morbidity and mortality in a cohort of long-term hemodialysis patients. | Atrial fibrillation is associated with increased mortality and hospitalization in the general population. Data about mortality, morbidity, and hospitalization in hemodialysis patients with atrial fibrillation are limited.</AbstractText><AbstractText Label="SETTING & PARTICIPANTS" NlmCategory="METHODS">All patients ... |
8,009 | Atrial fibrillation and obesity--results of a meta-analysis. | Obesity has been shown to be associated with atrial enlargement and ventricular diastolic dysfunction, both of which are risk factors for atrial fibrillation (AF). However, the role of obesity as a risk factor for the development of AF is unknown. The study aims to evaluate the role of obesity as a risk factor for the ... |
8,010 | Doppler predictors of inducibility of atrial fibrillation in patients with WPW syndrome and atrioventricular re-entrant tachycardia. | Atrial fibrillation (AF) in patients with Wolff-Parkinson-White syndrome (WPW) may induce complex ventricular arrhythmias resulting in sudden cardiac death. It is essential to find an effective non-invasive diagnostic method allowing to select patients at risk of life-threatening arrhythmias. Our objective was to exami... |
8,011 | Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction. | Brugada syndrome is one of the important causes of sudden cardiac death in young adults. The condition is associated with typical ECG changes in anteroseptal leads V1 and V2 that can be unmasked by various medications, electrolyte disturbances, and even by the febrile state in susceptible individuals. The case history ... |
8,012 | CT scan findings in oesophagogastric perforation after out of hospital cardiopulmonary resuscitation. | Rupture of the oesophagus or stomach at the time of cardiopulmonary resuscitation can occur with accidental oesophageal intubation. The common site of rupture is the lesser curvature of the stomach, but can also occur at the oesophagogastric junction. The patient presented with a massive pneumoperitoneum after an out o... |
8,013 | TASER X26 discharges in swine produce potentially fatal ventricular arrhythmias. | Data from the authors and others suggest that TASER X26 stun devices can acutely alter cardiac function in swine. The authors hypothesized that TASER discharges degrade cardiac performance through a mechanism not involving concurrent acidosis.</AbstractText>Using an Institutional Animal Care and Use Committee (IACUC)-a... |
8,014 | [Intraoperative coronary artery spasm with cardiac arrest: cardiologic acute intervention]. | Ventricular fibrillation occurred intraoperatively during a laparoscopy-assisted resection of the rectum in a 63-year-old patient. A coronary artery spasm was identified as the cause. It was possible to rectify the coronary artery spasm and restore a stable circulatory situation with an intracoronary injection of nitro... |
8,015 | [Reversible dilated cardiomyopathy related to hyperthyroidism]. | Heart failure is one of the most known complications of hyperthyroidism, more commonly high-output heart failure, but some patients may develop dilated cardiomyopathy with low ejection fraction. We report a 35-year-old man, with hyperthyroidism, atrial fibrillation, and severe heart failure with 43% of ejection fractio... |
8,016 | Long-term effects of cardiac resynchronisation therapy in patients with atrial fibrillation. | To compare the effects of cardiac resynchronisation therapy (CRT) in patients with heart failure (HF) in either atrial fibrillation (AF) or sinus rhythm (SR).</AbstractText>Prospective observational study.</AbstractText>295 consecutive patients with HF (permanent AF in 66, paroxysmal AF in 20, SR in 209; New York Heart... |
8,017 | Effects of spironolactone on electrical and structural remodeling of atrium in congestive heart failure dogs. | Renin-angiotensin-aldosterone system has been demonstrated to be associated with both congestive heart failure (CHF) and atrial fibrillation (AF). This study investigated the effects of spironolactone, a kind of aldosterone antagonist, on atrial electrical remodeling and fibrosis in CHF dogs induced by chronic rapid ve... |
8,018 | Predictive factors of recurrent angina after acute coronary syndrome: the global registry acute coronary events from China (Sino-GRACE). | Many patients with acute coronary syndrome (ACS) develop recurrent angina (RA) during hospitalization. The aim of this non-randomized, prospective study was to investigate the predictive factors of RA in unselected patients with ACS enrolled in the global registry acute coronary events (GRACE) during hospitalization in... |
8,019 | Rapidly induced selective cerebral hypothermia using a cold carotid arterial flush during cardiac arrest in a dog model. | The present study was undertaken to determine whether flushing the carotid artery with normal saline at 4 degrees C (hypothermic carotid arterial flush, HCAF) during cardiac arrest can achieve selective cerebral hypothermia rapidly during cardiac arrest and improve cerebral outcome.</AbstractText>Ventricular fibrillati... |
8,020 | Risk stratification for primary implantation of a cardioverter-defibrillator in patients with ischemic left ventricular dysfunction. | The study was designed to develop a simple risk stratification score for primary therapy with an implantable cardioverter-defibrillator (ICD).</AbstractText>Current guidelines recommend primary ICD therapy in patients with a low ejection fraction (EF). However, the benefit of the ICD in the low EF population may not be... |
8,021 | The impact of carvedilol on the defibrillation threshold. | Defibrillation threshold (DFT) is the minimum energy required to successfully terminate ventricular fibrillation. Epinephrine has been shown to increase the DFT in the beta-blocker naïve, but using cardioselective beta-blockers leads to a reduction in the DFT on infusion of epinephrine and norepinephrine. We sough... |
8,022 | Acute in vivo evaluation of an implantable continuous flow biventricular assist system. | An implantable biventricular assist device offers a considerable opportunity to save the lives of patients with combined irreversible right and left ventricular failure. The purpose of this study was to evaluate the hemodynamic and physiologic performance of the combined implantation of the CorAide left ventricular ass... |
8,023 | Artificial muscles to restore transport function of diseased atria. | Surgical treatment of persistent atrial fibrillation often fails to restore the transport function of the atrium. This study first introduces the concept of an atrial assist device to restore the pump function of the atrium. A micro motorless pump based on artificial muscle technology, is positioned on the external sur... |
8,024 | Home monitoring remote control of pacemaker and implantable cardioverter defibrillator patients in clinical practice: impact on medical management and health-care resource utilization. | To evaluate the impact of Home Monitoringtrade mark(HM) remote control on patient medical treatment and on health-care resource utilization.</AbstractText>One hundred and seventeen patients received HM pacemakers or defibrillators. A pacing expert nurse consulted daily the website and submitted critical cases to physic... |
8,025 | Long-term reliability of AAI mode pacing in patients with sinus node dysfunction and low Wenckebach block rate. | To compare the risk of atrioventricular (AV) conduction disturbance between patients with sinus node dysfunction on AAI pacing who had a low or high Wenckebach block rate (WBR).</AbstractText>Patients with sinus node dysfunction and normal AV conduction those underwent an electrophysiological study were studied. The pa... |
8,026 | Esmolol facilitated extubation in a patient with severe systolic dysfunction following myocardial infarction. | We describe the case of a 59-year-old-man with acute myocardial infarction and severely impaired left ventricular systolic function who was intubated because of recurrent ventricular fibrillation in the setting of coronary angioplasty. Repeated ventilator weaning attempts and extubation initially failed, as severe tach... |
8,027 | Fish-oil supplementation in patients with implantable cardioverter defibrillators: a meta-analysis. | A recent Cochrane meta-analysis did not confirm the benefits of fish and fish oil in the secondary prevention of cardiac death and myocardial infarction. We performed a meta-analysis of randomized controlled trials that examined the effect of fish-oil supplementation on ventricular fibrillation and ventricular tachycar... |
8,028 | Safety considerations in the pharmacological management of atrial fibrillation. | The pharmacological management of atrial fibrillation (AF) requires careful consideration from a safety perspective. This article focuses primarily on maintenance therapy using antiarrhythmic drugs (AADs). The foremost safety issue for AADs is the propensity of class IA and III agents to cause torsade de pointes arrhyt... |
8,029 | Impact of ambulance crew configuration on simulated cardiac arrest resuscitation. | Despite the widespread use of both two paramedic and single paramedic ambulance crews, there is little evidence regarding differences between these two staffing configurations in the delivery of patient care.</AbstractText>To determine potential differences in care provided by each of these ambulance configurations in ... |
8,030 | Effects of region of interest tracking on the diagnosis of left ventricular dyssynchrony from Doppler tissue images. | Left ventricular dyssynchrony is often diagnosed by comparing velocity curves from Doppler tissue images of two or more myocardial regions. Velocity curves are generated by placing sample volumes or regions of interest (ROIs) within the myocardium. ROIs need to be manually relocated to maintain a midmyocardial location... |
8,031 | Left atrial volume is a predictor of atrial fibrillation recurrence after catheter ablation. | Recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA) is not uncommon, and the predictors of AF recurrence are not completely understood. This study aimed to investigate the clinical and echocardiographic factors associated with AF recurrence after RFCA.</AbstractText>Sixty-eight patients... |
8,032 | Evaluation of the skin-to-heart distance in the standing adult by two-dimensional echocardiography. | An electromuscular incapacitating device (EMD) delivers pulses of high-voltage electricity, causing strong muscle contraction. Data from a pig model suggest that an EMD dart tip placed within 17 mm of the epicardial surface can cause ventricular fibrillation. The current study estimates minimum skin-to-heart distance i... |
8,033 | Enlarged right ventricle without shock in acute pulmonary embolism: prognosis. | An unsettled issue is the use of thrombolytic agents in patients with acute pulmonary embolism (PE) who are hemodynamically stable but have right ventricular (RV) enlargement. We assessed the in-hospital mortality of hemodynamically stable patients with PE and RV enlargement.</AbstractText>Patients were enrolled in the... |
8,034 | The feasibility of tissue Doppler acceleration as a new predictor of thrombogenesis in the left atrial appendage associated with nonvalvular atrial fibrillation. | Tissue acceleration utilizing the tissue Doppler imaging (TDI) technique is a new marker of ventricular contraction. We evaluated whether the left atrial appendage (LAA) wall acceleration was associated with thrombosis in patients with nonvalvular atrial fibrillation (NVAF).</AbstractText>Seven NVAF patients with throm... |
8,035 | Combination therapy of renin angiotensin system inhibitors and bepridil is useful for maintaining sinus rhythm in patients with atrial fibrillation. | The present study evaluated the effect of treatment renin angiotensin system inhibitors (RAS-I) for maintaining sinus rhythm after conversion from persistent atrial fibrillation. As the efficacy of RAS-I in atrial fibrillation is unclear, our study evaluated conversion to and maintenance of sinus rhythm by combination ... |
8,036 | Trends in mortality from acute myocardial infarction in the coronary care unit. | The treatment and outcome of acute myocardial infarction (AMI) has evolved greatly over the past few decades. We compared the mortality and complication rates of patients with AMI admitted to the Coronary Care Unit (CCU) in 2002 to previously reported data.</AbstractText>All data for AMI patients admitted to National H... |
8,037 | Clinical effects of leukofiltration and surface modification on post-cardiopulmonary bypass atrial fibrillation in different risk cohorts. | A manifestation of inflammatory injury to the heart, atrial fibrillation (AF), ranks among the most frequent and potentially life-threatening post-operative complications.</AbstractText>In a prospective randomized study, 120 patients undergoing CABG were allocated into two groups (N = 60): Group 1: Polymethoxyethylacry... |
8,038 | Sudden cardiac death risk factors in patients with heart failure treated with carvedilol. | Chronic heart failure (CHF) is associated with a high risk of sudden cardiac death (SCD). Most frequently SCD occurs in patients with NYHA class II and III.</AbstractText>To evaluate the influence of prolonged carvedilol therapy on SCD risk in CHF patients.</AbstractText>The study included 86 patients (81 men and 5 wom... |
8,039 | Calcium transient dynamics and the mechanisms of ventricular vulnerability to single premature electrical stimulation in Langendorff-perfused rabbit ventricles. | Single strong premature electrical stimulation (S(2)) may induce figure-eight reentry. We hypothesize that Ca current-mediated slow-response action potentials (APs) play a key role in the propagation in the central common pathway (CCP) of the reentry.</AbstractText>We simultaneously mapped optical membrane potential (V... |
8,040 | Electrocardiographic factors playing a role in ischemic ventricular fibrillation in ST elevation myocardial infarction are related to the culprit artery. | Sudden cardiac death caused by ischemic ventricular fibrillation (VF) associated with ST elevation myocardial infarction (STEMI) is one of the most frequent causes of death.</AbstractText>We hypothesized that electrocardiographic (ECG) characteristics differ between STEMI patients with and without ischemic VF.</Abstrac... |
8,041 | Clinical trials update from the American Heart Association 2007: CORONA, RethinQ, MASCOT, AF-CHF, HART, MASTER, POISE and stem cell therapy. | This article provides information and a commentary on trials relevant to the pathophysiology, prevention and treatment of heart failure, presented at the American Heart Association 2007. These should be considered as preliminary data, as analyses may change in the final publication. Rosuvastatin did not reduce mortalit... |
8,042 | Pulmonary edema after extensive radiofrequency ablation for atrial fibrillation. | More extensive ablation strategies for the treatment of atrial fibrillation (AF) have increased success rates but are associated with new and sometimes serious complications. We describe a new complication after extensive radiofrequency (RF) ablation in the left atrium (LA) for persistent AF.</AbstractText>Electroanato... |
8,043 | Experimental studies of atrial fibrillation: a comparison of two pacing models. | Rapid ventricular pacing (RVP) is a well-established animal model of atrial fibrillation (AF). However, this model is limited by a high mortality rate and severe heart failure. The purpose of our study was to assess a new canine model of inducible AF. We performed acute, short-term, simultaneous atrioventricular pacing... |
8,044 | P wave detector with PP rhythm tracking: evaluation in different arrhythmia contexts. | Automatic detection of atrial activity (P waves) in an electrocardiogram (ECG) is a crucial task to diagnose the presence of arrhythmias. The P wave is difficult to detect and most of the approaches in the literature have been evaluated on normal sinus rhythms and rarely considered arrhythmia contexts other than atrial... |
8,045 | [Sudden cardiac death--an assessment of pre-hospital proceedings]. | Sudden cardiac death (SCD) constitutes 13-18.5% of all natural deaths. This problem is socially and economically important because it affects often young people who are still professionally active. Many factors connected with the survival of the patients are beyond the emergency services' scope of operation. Patients d... |
8,046 | Lethal presentations of coronary artery spasm after an event-free period of six years following initial diagnosis. | Isolated coronary artery spasm without atherosclerotic obstruction is an unusual cause of myocardial infarction (MI). A middle-aged woman presented to our institution in 2001 with acute inferior MI due to coronary artery spasm at the mid segment of the dominant left circumflex coronary artery. After being well for 6 ye... |
8,047 | Mid-ventricular hypertrophic obstructive cardiomyopathy presenting with acute myocardial infarction. | Mid-ventricular hypertrophic obstructive cardiomyopathy is a rare type of cardiomyopathy that can be accompanied by apical aneurysm. We report the case of a patient who presented with ventricular fibrillation, ST-segment elevation on electrocardiography, and cardiac-enzyme elevation, in the presence of normal coronary ... |
8,048 | Outcome of cardiac arrests attended by emergency medical services staff at community outpatient dialysis centers. | Cardiac arrest is the leading cause of death among dialysis patients in the United States. We measured the outcome of cardiac arrests attended by Emergency Medical Services (EMS) staff at hemodialysis facilities in a 14-year population-based retrospective study to identify cardiac arrest cases at a dialysis unit. Assoc... |
8,049 | Delayed time to defibrillation after in-hospital cardiac arrest. | Expert guidelines advocate defibrillation within 2 minutes after an in-hospital cardiac arrest caused by ventricular arrhythmia. However, empirical data on the prevalence of delayed defibrillation in the United States and its effect on survival are limited.</AbstractText>We identified 6789 patients who had cardiac arre... |
8,050 | Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling. | Recently, activation of the local renin-angiotensin system and mitogen-activated protein kinase pathways in atrial myocardium has been found to play an important role in atrial structural remodeling related to atrial fibrillation. Another important mediator of the angiotensin II (Ang II) effect is the Janus kinase/sign... |
8,051 | How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation? | Current pharmacologic strategies for the management of Atrial fibrillation (AF) include use of 1) sodium channel blockers, which are contraindicated in patients with coronary artery or structural heart disease because of their potent effect to slow conduction in the ventricles, 2) potassium channel blockers, which pred... |
8,052 | Prediction of early mortality in primary intracerebral hemorrhage in an Asian population. | Primary intracerebral hemorrhage accounts for the relative minority of all strokes and yet is more fatal and disabling. Various prognostic models for mortality and functional outcome following primary intracerebral hemorrhage have been proposed, however there is little data which focuses on a multi-racial population pr... |
8,053 | Characteristic of the prevalence of J wave in apparently healthy Chinese adults. | The J wave has been seen in idiopathic ventricular fibrillation, Brugada syndrome, and early repolarization syndrome. Although these conditions share some ECG features, the clinical consequences are markedly different. J wave presentation in healthy subjects is not a rare phenomenon, although its characteristics are po... |
8,054 | Periodic acceleration (pGz) CPR in a swine model of asphyxia induced cardiac arrest. Short-term hemodynamic comparisons. | Asphyxia is one of the most common causes of pediatric cardiac arrest, and becoming a more frequently recognized cause in adults. Periodic acceleration (pGz) is a novel method of cardiopulmonary resuscitation (CPR). pGz is achieved by rapid motion of the supine body headward-footward that generates adequate perfusion a... |
8,055 | A case of Commotio cordis in a young child caused by a fall. | Commotio cordis or ventricular fibrillation caused by a blow to the chest is a rare cause of cardiac arrest in a well child. We report a case of a young child falling from a low height landing chest first with rapid onset of unconsciousness, apnoea and cyanosis. Cardiopulmonary resuscitation was given by parents under ... |
8,056 | Light chain deposition disease presenting as paroxysmal atrial fibrillation: a case report. | Light chain deposition disease (LCDD) can involve the heart and cause severe heart failure. Cardiac involvement is usually described in the advanced stages of the disease. We report the case of a woman in whom restrictive cardiomyopathy due to LCDD presented with paroxysmal atrial fibrillation.</AbstractText>A 55-year-... |
8,057 | Vulnerability to re-entry in simulated two-dimensional cardiac tissue: effects of electrical restitution and stimulation sequence. | Ventricular fibrillation is a lethal arrhythmia characterized by multiple wavelets usually starting from a single or figure-of-eight re-entrant circuit. Understanding the factors regulating vulnerability to the re-entry is essential for developing effective therapeutic strategies to prevent ventricular fibrillation. In... |
8,058 | Coronary artery spasm as a cause of ST elevation and inappropriate implantable cardioverter defibrillator intervention. | Coronary artery spasm can cause both brady- and tachyarrhythmia, through induction of AV block (usually linked to coronary spasm of the right coronary artery) or ventricular tachycardia/fibrillation linked to extensive myocardial ischemia. The electrocardiographic aspect of coronary artery spasm is an ST segment elevat... |
8,059 | Prophylactic catheter ablation for the prevention of defibrillator therapy. | For patients who have a ventricular tachyarrhythmic event, implantable cardioverter-defibrillators (ICDs) are a mainstay of therapy to prevent sudden death. However, ICD shocks are painful, can result in clinical depression, and do not offer complete protection against death from arrhythmia. We designed this randomized... |
8,060 | Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics. | The L-type Ca current (I(Ca,L)), essential for normal cardiac function, also regulates dynamic action potential (AP) properties that promote ventricular fibrillation. Blocking I(Ca,L) can prevent ventricular fibrillation, but only at levels suppressing contractility. We speculated that, instead of blocking I(Ca,L), mod... |
8,061 | A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. | Mathematical modeling of the cardiac action potential has proven to be a powerful tool for illuminating various aspects of cardiac function, including cardiac arrhythmias. However, no currently available detailed action potential model accurately reproduces the dynamics of the cardiac action potential and intracellular... |
8,062 | Electrophysiologic study-guided amiodarone for sustained ventricular tachyarrhythmias associated with structural heart diseases. | Although an electrophysiologic study (EPS) and Holter-monitoring are often helpful in evaluating the efficacy of antiarrhythmic drugs in patients with ventricular tachyarrhythmias (ventricular tachycardia/fibrillation (VT/VF)), the efficacy of EPS- or Holter-guided oral amiodarone therapy in Japanese patients is still ... |
8,063 | Influence of valvular insufficiency and recurrent airway obstruction on haemodynamics and therapy in warmblood horses with atrial fibrillation. | The aim of this study was to investigate the potential haemodynamic effects of valvular insufficiency and recurrent airway obstruction (RAO) in horses with atrial fibrillation (AF). Therefore in ten healthy horses (group 1) and 40 horses with AF a clinical examination, a lung examination, echocardiography and right hea... |
8,064 | Relation of recurrence of atrial fibrillation after non-ST-elevation acute myocardial infarction to left atrial abnormality. | Atrial fibrillation (AF) is common during the course of acute myocardial infarction and is associated with left atrial (LA) dilatation. However, the role of LA depolarization abnormality on the electrocardiogram (ECG) in the setting of LA dilatation was not studied in this context. Patients admitted with non-ST-segment... |
8,065 | Trimetazidine protective effect against ischemia-induced susceptibility to ventricular fibrillation in pigs. | Ventricular fibrillation (VF) is a possible consequence of brief myocardial ischemia. Such a short ischemia does not provoke cell damage, but induces changes in intracellular cardiac metabolism due to diminished oxygen supply to the heart. Trimetazidine (TMZ) is a drug able to restore the metabolic balance between fatt... |
8,066 | Pre-excited atrial fibrillation triggered by intravenous adenosine: a commonly used drug with potentially life-threatening adverse effects. | Although serious adverse events following adenosine administration are rare, it should only be administered in an environment where continuous ECG monitoring and emergency resuscitation equipment are available. The case report describes the development of pre-excited atrial fibrillation in a 31-year-old woman with Wolf... |
8,067 | Erythropoietin pretreatment protects against acute chemotherapy toxicity in isolated rat hearts. | The use of chemotherapeutic agents, such as anthracycline or trastuzumab, in oncology is limited by their cardiac toxicity. Recent experimental studies suggest that recombinant human erythropoietin (rhEPO) can be considered as a protective agent because its administration protects against cardiac ischemic injury, impro... |
8,068 | Arrhythmogenic right ventricular cardiomyopathy/dysplasia: risk stratification and therapy. | Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is an inherited heart muscle disease that occurs primarily in young and middle-age individuals. It is characterized by ventricular arrhythmias (VA), sudden death, and by heart failure occurring later in life (–5). Ventricular electrical instabili... |
8,069 | [Ventricular fibrillation following deodorant spray inhalation]. | We report one case of out-of-hospital cardiac arrest with ventricular fibrillation following butane poisoning after inhalation of antiperspiration aerosol. An early management using semi-automatic defibrillator explained the success of the resuscitation. The mechanism of butane toxicity could be an increased sensitivit... |
8,070 | T-wave alternans, restitution of human action potential duration, and outcome. | Our aim was to study the relationship between T-wave alternans (TWA) and rate-response (restitution) of repolarization in subjects with and without ventricular systolic dysfunction.</AbstractText>T-wave alternans is a promising predictor of sudden death, yet the mechanisms linking it with human ventricular arrhythmias ... |
8,071 | Right isthmus ablation reduces supraventricular arrhythmias after surgery for chronic atrial fibrillation. | Clinical, electrocardiographic, and echocardiographic results of atrial fibrillation (AF) ablation by left mini-Maze, with or without concomitant cavotricuspid isthmus ablation, during cardiac surgery were analyzed.</AbstractText>Eighty-seven patients undergoing radiofrequency left mini-Maze without (group A) or with (... |
8,072 | Cardiac side effects of psychiatric drugs. | This review describes the common effects of psychotropic drugs on the cardiovascular system and offers guidance for practical management. Selected reports from the literature describing common side effects associated with psychotropic drugs are reviewed, and suggestions for further reading are given throughout the text... |
8,073 | Electrocardiographic evidence of ventricular repolarization remodelling during atrial fibrillation. | Some atrial fibrillation (AF) patients develop excessive QTc prolongation and torsade de pointes when they take QTc-prolonging antiarrhythmic drugs (class IA/III) immediately after termination of AF. We hypothesized that this is caused by changes in ventricular repolarization during AF. We aimed to establish whether su... |
8,074 | Universal scaling law of electrical turbulence in the mammalian heart. | Many biological processes, such as metabolic rate and life span, scale with body mass (BM) according to the universal law of allometric scaling: Y = aBM(b) (Y, biological process; b, scaling exponent). We investigated whether the temporal properties of ventricular fibrillation (VF), the major cause of sudden and unexpe... |
8,075 | ST segment elevation on electrocardiogram: the electrocardiographic pattern of Brugada syndrome. | A 77-year-old white diabetic woman was brought to our emergency department (ED) after becoming lightheaded and hypotensive at home. Her routine tests including a chest radiograph were normal. Her electrocardiogram (ECG) showed significant ST segment elevation in leads V1 to V4. Serial cardiac enzymes and troponin were ... |
8,076 | The role of intracardiac echocardiography in interventional electrophysiology. | Visualization of the cardiac anatomy becomes more and more important as the complexity of interventions increases. Intracardiac echocardiography (ICE) provides good depiction of cardiac soft tissue structures and has become an important tool in today's cardiology. It has been shown to be valuable during many ablation p... |
8,077 | S1P1-selective agonist SEW2871 exacerbates reperfusion arrhythmias. | Sphingosine-1-phosphate (S1P) has been considered to play an important role in ischemia/reperfusion (I/R) injury. We used SEW2871 (SEW), a novel receptor-selective agonist for S1P1, to elucidate the role of S1P1 in myocardial I/R. Isolated perfused rat hearts exposed to S1P (1 and 10 mM) or SEW (1 and 0.1 mM) were subj... |
8,078 | The impact of acute myocardial ischemia on the ventricular defibrillation threshold during chronic oral azimilide therapy. | The effects of chronic oral azimilide therapy on the ventricular defibrillation threshold (DFT) during ischemia are unknown. The effects of azimilide on defibrillation efficacy under ischemic condition were investigated in a closed-chest animal model. Azimilide (20 mg/kg/d) was administered orally for 7 days to 10 pigs... |
8,079 | Postresuscitation myocardial diastolic dysfunction following prolonged ventricular fibrillation and cardiopulmonary resuscitation. | Postresuscitation myocardial dysfunction is one of the leading causes of early death after successful resuscitation from sudden death. However, the diastolic characteristics of postresuscitation myocardial dysfunction are not well defined. We therefore investigated the postresuscitation left ventricular diastolic funct... |
8,080 | Identifying potentially shockable rhythms without interrupting cardiopulmonary resuscitation. | Current versions of automated external defibrillators (AEDs) mandate interruptions of chest compression for rhythm analyses because of artifacts produced by chest compressions. Interruption of chest compressions reduces likelihood of successful resuscitation by as much as 50%. We sought a method to identify a shockable... |
8,081 | Electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. | Newer guidelines address the importance of effective chest compressions, citing evidence that this primary intervention is usually suboptimally performed during cardiopulmonary resuscitation. We therefore sought a readily available option for monitoring the effectiveness of chest compressions, specifically using the el... |
8,082 | Increasing amiodarone use in cardiopulmonary resuscitation: an analysis of the National Registry of Cardiopulmonary Resuscitation. | To examine practice patterns of amiodarone use during in-hospital cardiac arrest. This study addresses the changing pattern of amiodarone use over time, following the publication of landmark studies and the inclusion of amiodarone in the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emerge... |
8,083 | Cardiac resynchronization therapy in patients with chronic atrial fibrillation. | Heart failure (HF) and atrial fibrillation (AF), 2 of the most common cardiovascular disorders, often coexist in the same patient, as 1 condition can lead to the other. The best approach to AF management in patients with HF is currently under investigation, but there seems to be an abundance of evidence in support of c... |
8,084 | Mechanical properties of chest protectors and the likelihood of ventricular fibrillation due to commotio cordis. | Sudden death resulting from ventricular fibrillation (VF) caused by a nonpenetrating chest wall impact, known as commotio cordis (CC), is the second leading cause of death among young athletes. To date, seven young athletes wearing chest protectors have died from CC. The purpose of this study was to determine whether a... |
8,085 | Possible role of hydrogen sulfide on the preservation of donor rat hearts. | The aim of this study was to observe the preservative effect of hydrogen sulfide (H2S) on donor rat hearts.</AbstractText>The hearts of 24 Sprague-Dawley rats were perfused on a Langendorff perfusion column for 30 minutes. We calculated and recorded the left ventricular-developed pressure (LVDP), and positive and negat... |
8,086 | Therapeutic hypothermia in comatose patients after out-of-hospital cardiac arrest. | Our intensive care unit has been treating comatose patients, following an out-of-hospital cardiac arrest, with therapeutic hypothermia since 2002. In all, 139 out-of-hospital cardiac arrest patients were admitted in the 4-year period 2002-5. Of these, 27% had a favourable outcome (discharged home or to rehabilitation).... |
8,087 | [Invasive electrophysiology: complications, nightmares and their management]. | Most minor side effects of ablation in the right atrium and right ventricle relate to femoral venous catheterization but there is a small risk of severe complications including atrioventricular (AV) block, damage of surrounding structures and thromboembolic events. Impairment of AV conduction can occur during ablation ... |
8,088 | Increased prevalence of sustained return of spontaneous circulation following transition to biphasic waveform defibrillation. | We sought to assess the prevalence of shock-induced sustained return of spontaneous circulation (ROSC) and neurologically intact discharge survival before (1990-1997) and after (1998-2006) transition to biphasic waveform defibrillation in our population-controlled EMS setting.</AbstractText>All victims of out-of-hospit... |
8,089 | The effects of prostaglandin inhibition on whole-body ischemia-reperfusion in swine. | Prostaglandins (PGs), particularly PGE2 and PGI2, have a salutary effect on myocardial ischemia-reperfusion-induced myocardial damage.</AbstractText>We investigated acute PG synthesis inhibition on outcomes from whole-body ischemia-reperfusion injury using a well-characterized model of ventricular fibrillation (VF)-ind... |
8,090 | Right atrial pacing and the risk of postimplant atrial fibrillation in cardiac resynchronization therapy recipients. | In patients with cardiac resynchronization therapy (CRT) devices, right atrial (RA) pacing introduces a significant prolongation in interatrial conduction time, delaying left atrial mechanical systole and curtailing left ventricular filling. The resultant increase in left-sided filling pressures may facilitate atrial f... |
8,091 | An unusual precipitant of tako-tsubo cardiomyopathy. | A 76-year-old woman presents with acute pulmonary oedema and cardiogenic shock 10h after elective electrical cardioversion for atrial fibrillation. Her echocardiogram shows new wall motion abnormalities with akinesis of the apical and mid segments of the left ventricle and her resting ECG contains deep T wave inversion... |
8,092 | Brugada syndrome in pure black Africans. | Although all races are concerned with the Brugada syndrome, no case has ever been reported among black Africans. We describe five different cases in this specific group of populations.</AbstractText>In all patients, Brugada syndrome was identified after detailed noninvasive and invasive evaluations. Sex ratio was four ... |
8,093 | [Direct referral of patients with ST-elevation acute myocardial infarction to primary percutaneous coronary intervention. Pre-hospital use of telemedicine and risk stratification]. | Primary percutaneous coronary intervention (PCI) is recommended for revascularisation of patients with ST-elevation acute myocardial infarction (STEMI) with a duration of symptoms less than 12 hours. Primary PCI is recommended even if the patient is to be transported from a non-invasive hospital to an invasive centre. ... |
8,094 | A multiple ion channel blocker, NIP-142, for the treatment of atrial fibrillation. | Atrial fibrillation (AF) is one of the most frequent cardiac arrhythmia and is associated with increased cardiovascular morbidity and mortality, and the risk of stroke. Although currently available antiarrhythmic drugs are moderately effective in restoring normal sinus rhythm in patients with AF, excessive delay of ven... |
8,095 | [Preoperative evaluation and anesthetic management of a patient with Brugada syndrome-like ECG]. | Brugada syndrome has been known as one of the causes of sudden death due to ventricular fibrillation. We experienced anesthetic management of seven patients with ECG showing Brugada syndrome before surgery, even though they had no symptoms nor family history. All of them showed no problems through-out the operation. Su... |
8,096 | [Therapeutic effect of p-tyrosol on myocardial electric instability induced by coronary occlusion]. | In experiments on rats with left coronary artery occlusion, p-tyrosol (20 mg/kg, intravenously) showed the ability to decrease myocardial electric instability in phase 1b of ventricular arrhythmias: a fraction of rats without arrhythmia was increased by 36%, and the mean value of ventricular arrhythmia index exhibited ... |
8,097 | Acute effects of TASER X26 discharges in a swine model. | Very little objective laboratory data are available describing the physiologic effects of stun guns or electromuscular incapacitation devices (EIDs). Unfortunately, there have been several hundred in-custody deaths, which have been temporally associated with the deployment of these devices. Most of the deaths have been... |
8,098 | Progressive mitral valve thickening and progressive muscle cramps as manifestations of glycogenosis VII (Tarui's Disease). | Progressive heart valve thickening and shrinkage, and progressive muscle cramps have not been reported as manifestations of glycogenosis type VII (Tarui's disease). In a 72-year-old female, Tarui's disease was diagnosed in 1997, initially manifesting as simple partial seizures since 1977, anginal chest pain since 1982 ... |
8,099 | Acute clenbuterol overdose resulting in supraventricular tachycardia and atrial fibrillation. | We are presenting a case illustrating the complex metabolic and rhythm disturbances associated with acute clenbuterol intoxication.</AbstractText>Clenbuterol is a long-acting beta2-adrenergic agonist primarily used in veterinary medicine in the United States. It has become a common drug of abuse by body builders becaus... |
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