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8,200 | Higher prevalence of cardiovascular events among patients with abnormal atrial depolarization and coronary artery disease at 18 months' post-exercise tolerance testing. | Abnormal atrial depolarization, denoted as interatrial block (IAB; P wave >110 ms), is associated with myocardial ischemia during exercise. The authors conducted an 18-month follow-up for cardiovascular events in 31 consecutive patients with IAB and 60 controls without IAB at rest; participants had coronary artery d... |
8,201 | Depressive symptoms predict recurrence of atrial fibrillation after cardioversion. | The aim of this study was to evaluate whether depressive symptoms and the type-D personality are predictive of early recurrence of atrial fibrillation (or atrial flutter; AF) after successful electrical cardioversion (CV).</AbstractText>Depressive symptoms are associated with an adverse prognosis in patients with coron... |
8,202 | Effects of tamoxifen on myocardial ischemia-reperfusion injury model in ovariectomized rats. | The purpose of this study is to examine the antiarrhythmic and antioxidant effects of tamoxifen, one of the selective estrogen modulators, in ovariectomized rats subjected to myocardial ischemia-reperfusion (I/R) injury. A month after ovariectomy, rats were divided into four groups: (I) ovariectomized controls without ... |
8,203 | Beta-blocker use and the changing epidemiology of out-of-hospital cardiac arrest rhythms. | The incidence of ventricular fibrillation (VF) as the presenting rhythm in out-of-hospital cardiac arrest (OHCA) is declining, whereas pulseless electrical activity (PEA) is increasing. This changing epidemiology has occurred concomitant with an increase in beta-blocker use.</AbstractText>The aim of this study was to m... |
8,204 | Idiopathic cardiac electrical storm. | Cardiac electrical storm has been described as three or more distinct episodes of ventricular fibrillation or hemodynamically destabilizing ventricular tachycardia in a 24-h period, typically requiring treatment with electrical cardioversion or defibrillation. We report the case of a 45-year-old man who presented to th... |
8,205 | Inappropriate defibrillator shocks from depolarization--repolarization mismatch in a patient with hypertrophy cardiomyopathy. | Despite wide use of dedicated bipolar sensing electrodes in implantable cardioverter-defibrillator (ICD) systems, oversensing occasionally occurs, leading to unwarranted shocks or antitachycardia pacing. This case report highlights an individual with hypertrophic cardiomyopathy (HCM) who experienced inappropriate shock... |
8,206 | Cardiac resynchronization therapy response is associated with shorter duration of atrial fibrillation. | Atrial fibrillation (AF) is commonly associated with heart failure. The benefit of cardiac resynchronization therapy (CRT) on atrial remodeling has been demonstrated. However, biventricular pacing did not reduce the global incidence of AF. We evaluated the relationship between CRT response and AF duration.</AbstractTex... |
8,207 | [Experimental studies on antiarrhythmic effect of jumi extraction]. | To investigate the antiarrhythmic effect of jumi (JM) extraction.</AbstractText>The conventional antiarrhythmic methods were used.</AbstractText>Administration of JM extraction reduced the occurrence of ventricular fibrillation induced by chloroform in a dose-dependent manner in mice. Quinidine significantly decreased ... |
8,208 | Clinical and echocardiographic parameters and score for the left atrial thrombus formation prediction in the patients with mitral stenosis. | Rheumatic mitral stenosis is one of the important health problems, especially in Thailand. Thromboembolic complications from this disease remain the major problem in these patients. These complications are usually related to the left atrial thrombus formation.</AbstractText>To determine the parameters that can predict ... |
8,209 | [Drugs for heart rate control and non-antiarrhythmic drugs in atrial fibrillation]. | Multiple drugs are helpful for rate control in different tachyarrhythmias, in particular atrial fibrillation (AF). Betablockers (betaB) and calcium channel blockers have been used as monotherapy or as adjunctive therapy to antiarrhythmics for mantaining an acceptable ventricular rate. In recent years new concepts about... |
8,210 | [Arrhythmias in pregnancy. How and when to treat?]. | Cardiac arrhythmias can develop during pregnancy. The risk of arrhythmias is relatively higher during labor and delivery. Potential factors that can promote arrhythmias in pregnancy or during labor and delivery, include the direct cardiac electrophysiological effects of hormones, changes in autonomic tone, hemodynamic ... |
8,211 | Preserved left ventricular ejection fraction following atrioventricular junction ablation and pacing for atrial fibrillation. | Right ventricular apical (RVA) pacing creates ventricular dyssynchrony and may compromise left ventricular ejection fraction (LVEF). The impact of RVA pacing in patients who have undergone atrioventricular junction (AVJ) ablation for atrial fibrillation (AF) is unclear. We sought to determine whether RVA pacing after A... |
8,212 | Brugada syndrome subject to depolarization abnormality of the conduction system. | We report a patient who first developed Brugada syndrome (BS) after the conduction in atrioventricular (AV) node and the ventricular conduction system was disturbed. A type-1 Brugada ECG was unexpectedly unmasked after administration of a class IC antiarrhythmic agent for suppressing paroxysmal atrial fibrillation (paf... |
8,213 | Electrical storm in patients with an implanted defibrillator: a matter of definition. | The term "electrical storm" (ES) indicates a state of cardiac electrical instability manifested by several episodes of ventricular tachyarrhythmias (VTs) within a short time. In patients with an implantable cardioverter defibrillator (ICD), ES is best defined as 3 appropriate VT detections in 24 h, treated by antitachy... |
8,214 | Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias. | Brugada syndrome is a rare, autosomal-dominant, male-predominant form of idiopathic ventricular fibrillation characterized by a right bundle-branch block and ST elevation in the right precordial leads of the surface ECG. Mutations in the cardiac Na+ channel SCN5A on chromosome 3p21 cause approximately 20% of the cases ... |
8,215 | Atrial antifibrillatory effects of structurally distinct IKur blockers 3-[(dimethylamino)methyl]-6-methoxy-2-methyl-4-phenylisoquinolin-1(2H)-one and 2-phenyl-1,1-dipyridin-3-yl-2-pyrrolidin-1-yl-ethanol in dogs with underlying heart failure. | Drug discovery efforts have focused recently on atrial-selective targets, including the Kv1.5 channel, which underlies the ultrarapid delayed rectifier current, I(Kur), to develop novel treatments for atrial fibrillation (AF). Two structurally distinct compounds, a triarylethanolamine TAEA and an isoquinolinone 3-[(dim... |
8,216 | Ventricular fibrillation and the use of automated external defibrillators on children. | The use of automated external defibrillators (AEDs) has been advocated in recent years as a part of the chain of survival to improve outcomes for adult cardiac arrest victims. When AEDs first entered the market, they were not tested for pediatric usage and rhythm interpretation. In addition, the presumption was that ch... |
8,217 | 'Unexpected' sudden death avoided by implantable cardioverter defibrillator in Emery Dreifuss patient. | A female patient just over 20 years of age developed first grade atrioventricular block, and later atrial fibrillation. When she was 41 years old she was diagnosed with Emery-Dreifuss muscular dystrophy (EDMD). A VVIR pacemaker was implanted in 2002, replaced in 2003 with an ICD. Nine months later, during febrile illne... |
8,218 | Omega-3 polyunsaturated fatty acids prevent atrial fibrillation associated with heart failure but not atrial tachycardia remodeling. | There is epidemiological evidence that omega-3 polyunsaturated fatty acids (PUFAs) reduce the risk of atrial fibrillation (AF), but clinical data are conflicting. The present study assessed the effects of PUFA on AF in experimental models.</AbstractText>We studied the effects of oral PUFA supplements in 2 experimental ... |
8,219 | Secular trends of heart failure among US male physicians. | Heart failure (HF) remains a major public health issue. Data on long-term trends in the incidence of HF and survival after its onset are limited.</AbstractText>A prospective cohort study conducted between 1985 and 2004 in 21,906 participants of the Physicians' Health Study I who were alive and free of HF on January 1, ... |
8,220 | [Perioperative cardiac arrhythmias in patients undergoing surgical treatment for lung cancer]. | Thoracic surgery is associated with a high risk of morbidity and mortality. Cardiac arrhythmias are the most common and severe complications in early postoperative period.</AbstractText>Evaluation of the prevalence and causes of cardiac arrythmias, factors that predispose to their occurrence and their influence on gene... |
8,221 | Electromechanical characterization of cinnamophilin, a natural thromboxane A2 receptor antagonist with anti-arrhythmic activity, in guinea-pig heart. | Cinnamophilin, a thromboxane A(2) receptor antagonist, has been identified as a prominent anti-arrhythmic agent in rat heart. This study aimed to determine its electromechanical and anti-arrhythmic effects in guinea-pig hearts.</AbstractText>Microelectrodes were used to study action potentials in ventricular papillary ... |
8,222 | Value of echo-Doppler derived pulmonary vascular resistance, net-atrioventricular compliance and tricuspid annular velocity in determining exercise capacity in patients with mitral stenosis. | The present study sought to determine if echo-Doppler-derived pulmonary vascular resistance (PVR echo), net-atrioventricular compliance (Cn) and tricuspid peak systolic annular velocity (Sa), as parameters of right ventricular function, have value in predicting exercise capacity in patients with mitral stenosis (MS).</... |
8,223 | Mid-ventricular obstructive hypertrophic cardiomyopathy associated with an apical aneurysm: evaluation of possible causes of aneurysm formation. | Mid-ventricular obstructive hypertrophic cardiomyopathy (MVOHCM) is a rare type of cardiomyopathy, associated with apical aneurysm formation in some cases. We report a patient presenting with ventricular fibrillation, an ECG with an above normal ST segment, and elevated levels of cardiac enzymes but normal coronary art... |
8,224 | Bone marrow mononuclear stem cells transplanted in rat infarct myocardium improved the electrical conduction without evidence of proarrhythmic effects. | The arrhythmogenic effect of stem cells transplantation (SCT) in an infarct myocardium is still unknown. We investigated arrhythmogenicity of SCT in rat cryo-infarct model.</AbstractText>In rat cryo-infarct model, bone marrow mononuclear stem cells (MNSC, 1 x 10(7) cells) were transplanted into the infarct border zone ... |
8,225 | Commotio cordis as a result of a fight: report of a case considered to be imprudent homicide. | Commotio cordis is a clinic-pathological syndrome related to sudden death in young people involved in sports activities. It has been described, mainly, in athletes without previous cardiac anomalies who received a minor blow to the chest which produces ventricular fibrillation and cardiac arrest in the absence of struc... |
8,226 | [Tpeak-Tend interval and risk of cardiac events in patients with Brugada syndrome]. | To evaluate the possible association between Tpeak-Tend (Tp-e) interval in surface standard ECG and cardiac events in patients with Brugada syndrome (BrS).</AbstractText>Tp-e interval in surface standard ECG was compared between BrS patients (n = 23, all males) and paroxysmal supraventricular tachycardia (PSVT) patient... |
8,227 | Clinical significance of chemosensitivity in chronic heart failure: influence on neurohormonal derangement, Cheyne-Stokes respiration and arrhythmias. | Increased chemosensitivity has been observed in HF (heart failure) and, in order to clarify its pathophysiological and clinical relevance, the aim of the present study was to investigate its impact on neurohormonal balance, breathing pattern, response to exercise and arrhythmic profile. A total of 60 patients with chro... |
8,228 | Secondary prevention of ischemic stroke: evolution from a stepwise to a risk stratification approach to care. | Survivors of ischemic stroke are at significant risk for recurrent stroke. Appropriate therapy for stroke prevention is needed given the significant morbidity and mortality associated with stroke, the high financial costs, and the neurologic disability associated with treatment failure. A treatment strategy based on as... |
8,229 | Evaluation of pacemaker dependence in patients on ablate and pace therapy for atrial fibrillation. | In patients with atrial fibrillation (AF) and uncontrolled ventricular rate, radiofrequency (RF) ablation of the atrioventricular (AV) node and pacemaker (PM) implantation (ablate and pace) is a valid therapeutic approach, especially in elderly patients. The aim of our study was to evaluate the PM dependence and the in... |
8,230 | Different effects of cardiac resynchronization therapy on left atrial function in patients with either idiopathic or ischaemic dilated cardiomyopathy: a two-dimensional speckle strain study. | In dilated cardiomyopathy (DCM), attenuation of left atrial (LA) booster pump function has been observed, and attributed both to altered LA loading conditions owing to left ventricular (LV) diastolic dysfunction and to LA involvement in the myopathic process. The aim of the present study was to detect LA systolic dysfu... |
8,231 | [New aspects of cardiopulmonary resuscitation]. | To analyse the current knowledge based on the experimental and clinical research studies focused on cardiopulmonary resuscitation.</AbstractText>International guidelines and recent review articles. Data collected from the Medline database with the keyword: cardiac arrest (CA).</AbstractText>Research studies published d... |
8,232 | Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors. | The downregulation of phospholamban (PLB) and FKBP12.6 as a result of beta- receptor activation is involved in the pathway(s) of congestive heart failure. We hypothesized that the endothelin (ET)-1 system may link to downregulated PLB and FKBP12.6.</AbstractText>Rats were subjected to ischemia/reperfusion (I/R) to caus... |
8,233 | [Adult cardio-respiratory arrest: guidelines 2005-2010]. | At the end of 2005 the new guidelines for the treatment of cardiac arrest were published. The diagnostic criteria of cardiac arrest were simplified and priority is given to thoracic compressions. The ratio of thoracic compressions to insufflations is 30/2. The frequency of thoracic compression is 100/min. In ventricula... |
8,234 | Effect of induced ventricular fibrillation and shock delivery on brain natriuretic peptide measured serially following a predischarge ICD test. | Brain natriuretic peptide (BNP) was a marker for heart failure and cardiac wall tension. We analysed the trend of BNP after predischarge testing in order to get non-invasive details about the cardiac stress during predischarge testing.</AbstractText>4-5 days after ICD implant we measured BNP, myoglobin, cardiac troponi... |
8,235 | The role of abnormal trafficking of KCNE1 in long QT syndrome 5. | LQTS (long QT syndrome) is an important cause of cardiac sudden death. LQTS is characterized by a prolongation of the QT interval on an electrocardiogram. This prolongation predisposes the individual to torsade-de-pointes and subsequent sudden death by ventricular fibrillation. Mutations in a number of genes that encod... |
8,236 | Breakfast cereals and risk of heart failure in the physicians' health study I. | Heart failure (HF) is the leading cause of hospitalization among the elderly population in the United States. Consumption of grain products and dietary fiber has been shown to reduce the risk of hypertension and myocardial infarction. However, it is not known whether a higher consumption of breakfast cereals is associa... |
8,237 | Ventricular arrhythmia storms in postinfarction patients with implantable defibrillators for primary prevention indications: a MADIT-II substudy. | Much of prognostic implications of ventricular arrhythmia storms remain unclear.</AbstractText>We evaluated the risk associated with electrical storm in patients with defibrillators in the Multicenter Automatic Defibrillator Implantation Trial II (MADIT-II) study.</AbstractText>Electrical storm was defined as > or =... |
8,238 | Atrial paroxysmal tachycardia in dogs and its management with homeopathic Digitalis--two case reports. | Homeopathic Digitalis 6c was evaluated in two clinical cases of atrial paroxysmal tachycardia in dogs. Tachycardias are common cardiac problems in dogs, and atrial paroxysmal tachycardia is a serious cardiac arrhythmia that may lead to syncope. Both adult dogs (Labrador and German Shepherd) were treated with Digitalis ... |
8,239 | [Influence of recording mode (unipolar or bipolar) on the spectral characteristics of epicardial recordings in ventricular fibrillation. An experimental study]. | The aim of this study was to examine the hypothesis that the recording mode (i.e., unipolar or bipolar) affects the information obtained using spectral analysis techniques during ventricular fibrillation by carrying out an experiment using epicardial electrodes.</AbstractText>Recordings of ventricular fibrillation were... |
8,240 | [Left atrium diameter: a simple echocardiographic parameter with high prognostic value in heart failure]. | Left atrium diameter (LAD) is a very simple and easy parameter to obtain by echocardiography. It is influenced by systolic and diastolic ventricular dysfunction and by the coexistence of mitral regurgitation. We evaluated LAD as a predictor of prognosis (2 year mortality) in a heart failure (HF) population admitted to ... |
8,241 | Atrial fibrillation-related cardiomyopathy: a case report. | Sustained chronic tachyarrhythmias often cause a deterioration of cardiac function known as tachycardia-induced cardiomyopathy or tachycardiomyopathy.The incidence of tachycardia-induced cardiomyopathy is unknown, but in selected studies of patients with atrial fibrillation, approximately 25% to 50% of those with left ... |
8,242 | Electrophysiological consequence of adipose-derived stem cell transplantation in infarcted porcine myocardium. | Aim of this study was to investigate the effect of intracoronary administration of freshly isolated adipose-derived mononuclear cells (ADMCs) on myocardial vulnerability to arrhythmia induction after infarction.</AbstractText>A transmural myocardial infarction in an experimental porcine model was induced by occlusion o... |
8,243 | Comparison of the incidences of cardiac arrhythmias, myocardial ischemia, and cardiac events in patients treated with endovascular versus open surgical repair of abdominal aortic aneurysms. | This study examines differences in cardiac arrhythmias, perioperative myocardial ischemia, troponin T release, and cardiovascular events between endovascular and open repair of abdominal aortic aneurysms (AAAs). Of 175 patients, 126 underwent open AAA repair and 49 underwent endovascular AAA repair. Continuous 12-lead ... |
8,244 | Value of preoperative echocardiography in the prediction of postoperative atrial fibrillation following isolated coronary artery bypass grafting. | The value of echocardiography, especially tissue Doppler imaging (TDI), in the assessment of risk of postoperative atrial fibrillation (AF) after coronary artery bypass grafting (CABG) is not clear. One hundred two consecutive patients (80 men; mean age 61 +/- 10 years) who underwent elective isolated CABG were include... |
8,245 | Early right coronary vasospasm presenting with malignant arrhythmias in a heart transplantation recipient without allograft vasculopathy. | In heart transplant recipients, the aetiology of coronary vasospasm is largely unknown but it has been reported to be related to coronary vasculopathy or allograft rejection. We report a case of acute, reversible coronary vasospasm which caused malignant arrhythmias in a cardiac transplant recipient one month after tra... |
8,246 | Cardiac surgery in nonagenarians. | To evaluate outcomes following cardiac surgery in nonagenarians.</AbstractText>A retrospective analysis of patients > or = 90 years of age undergoing cardiac surgery at Barnes-Jewish Hospital from 1996-2006 was performed. The Social Security Death Index was used to determine late survival.</AbstractText>Twenty-two s... |
8,247 | Laminar arrangement of ventricular myocytes influences electrical behavior of the heart. | The response of the heart to electrical shock, electrical propagation in sinus rhythm, and the spatiotemporal dynamics of ventricular fibrillation all depend critically on the electrical anisotropy of cardiac tissue. A long-held view of cardiac electrical anisotropy is that electrical conductivity is greatest along the... |
8,248 | Predictive value of programmed ventricular stimulation in patients with ischaemic cardiomyopathy: implications for the selection of candidates for an implantable defibrillator. | The present study assessed the role of programmed ventricular stimulation (PVS) in risk stratification of patients with ischaemic cardiomyopathy (ICM), candidates for implantable cardioverter-defibrillator (ICD).</AbstractText>Consecutive patients with ICM and LVEF < or = 40% (n = 106, age 61 +/- 7 years, LVEF 27 +/... |
8,249 | Development of an algorithm for detection of fatal cardiac arrhythmia for implantable cardioverter-defibrillator using a self-organizing map. | In this study, we have introduced the pattern classifier using the self-organizing map (SOM) for detecting fatal cardiac arrhythmia in implantable cardioverter-defibrillators (ICDs). The SOM has learned patterns of sinus rhythm, ventricular fibrillation and ventricular tachycardia with the feature vectors extracted fro... |
8,250 | Maintenance of ventricular fibrillation in heterogeneous ventricle. | Although ventricular fibrillation (VF) is the prevalent cause of sudden cardiac death, the mechanisms that underlie VF remain elusive. One possible explanation is that VF is driven by a single robust rotor that is the source of wavefronts that break-up due to functional heterogeneities. Previous 2D computer simulations... |
8,251 | Development of a remote handheld cardiac arrhythmia monitor. | In this paper we present the design and development of a real-time remote handheld cardiac arrhythmic monitoring system (RCAM). A client-server model based on Internet protocols was used. ECG data was transmitted from the remote handheld client to a centralized server, where the QRS and premature ventricular contractio... |
8,252 | Cardiac current density distribution by electrical pulses from TASER devices. | TASERs deliver electrical pulses that can temporarily incapacitate subjects. The goal of this paper is to analyze the distribution of TASER currents in the heart and understand their chances of triggering cardiac arrhythmias. The models analyzed herein describe strength-duration thresholds for myocyte excitation and ve... |
8,253 | Development of arrhythmia diagnosis algorithm for effective control of antitachycardia pacing and high energy shock of ICD. | In this paper, we propose a modified arrhythmia diagnosis and therapy control algorithm based on VENTAK PRIZM 2 algorithm of the Guidant corp. Existing arrhythmia detection and therapy control algorithms control arrhythmia through two steps. First step is event detection using peak-to-peak interval detection, and the s... |
8,254 | Structural barrier increases QT-peak dispersion in swine left ventricle in vivo. | QT dispersion (QTD) is thought to represent the regional nonuniformity of ventricular repolarization and can serve as a prognostic marker for vulnerability to ventricular arrhythmias and risk for sudden cardiac death (SCD). In this study, we used an in vivo swine model to investigate the change of QT-peak dispersion be... |
8,255 | Automatic classification of heartbeats using neural network classifier based on a Bayesian framework. | This paper presents a method of automatic processing the electrocardiogram (ECG) signal for the classification of heart beats. Data were obtained from 48 records of the MIT-BIH arrhythmia database (only one lead). Five types of arrhythmic beats were classified using our method, Premature Ventricular Conduction beat (PV... |
8,256 | Calcium transients modulate action potential repolarizations in ventricular fibrillation. | Action potential alternans has been an indicator of ischemic disease and vulnerability to ventricular fibrillation (VF). The mechanisms of alternans are linked to the anomalies in intracellular Ca2+ (Cai) handling by either spontaneous Ca2+ release or modulation of action potential duration (APD), which may promote wav... |
8,257 | Comparison of current densities measured in a pig heart during states of ventricular fibrillation and post-mortem for different defibrillation electrode positions. | Current density imaging (CDI) is an MRI technique used to quantitatively measure current density vectors in biological tissue. A fast CDI sequence was developed that can image the whole body of a 4 kg pig in about 15 minutes. A state of ventricular fibrillation (VF) can be sustained for nearly 30 minutes allowing two c... |
8,258 | Method of post-shock synchronized pacing in the excitable gaps. | Ventricular fibrillation (VF) can be synchronized with a novel synchronized pacing technique (SyncP) using low-energy pacing pulses, which causes pace termination of VF. Synchronized pacing (SyncP) is defined as optical recording guided real-time detection and stimulation of spatiotemporal excitable gaps. In this paper... |
8,259 | Transmural electrophysiological heterogeneities in action potential duration increase the upper limit of vulnerability. | Transmural dispersion in action potential duration (APD) has been shown to contribute to arrhythmia induction in the heart. However, its role in termination of lethal arrhythmias by defibrillation shocks has never been examined. The goal of this study is to investigate how transmural dispersion in APD affects cardiac v... |
8,260 | Successful defibrillation in water: a preliminary study. | Mild hypothermia (32-34 deg C) treatment alleviates vital organ damage after cardiac arrest. A new cooling device, the Thermosuit operates by applying of a thin layer of water directly to the body surface. Hypothermic patients may experience sequential fibrillation. Therefore, we examined whether defibrillation could b... |
8,261 | Validation of a novel atrial fibrillation model through simulated atrial pacing protocols. | We have previously reported a novel model to elucidate the effects of ventricular pacing (VP) on RR intervals during atrial fibrillation (AF). This model treats the AV junction (AVJ) as a lumped structure with defined conductivity, refractoriness and automaticity. We have shown that this model could account for various... |
8,262 | Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism. | To investigate whether sodium-hydrogen exchanger isoform-1 (NHE-1) inhibition attenuates myocardial injury during resuscitation from ventricular fibrillation through effects on energy metabolism, using an open-chest pig model in which coronary perfusion was controlled by extracorporeal circulation.</AbstractText>Random... |
8,263 | Does the prognosis of cardiac arrest differ in trauma patients? | It is proposed to not resuscitate trauma patients who have a cardiac arrest outside the hospital because they are assumed to have a dismal prognosis. Our aim was to compare the outcome of patients with traumatic or nontraumatic ("medical") out-of-hospital cardiac arrest.</AbstractText>Cohort analysis of patients with o... |
8,264 | Myocardial function, ischaemia and n-3 polyunsaturated fatty acids: a membrane basis. | Long-chain n-3 polyunsaturated fatty acids (PUFAs) are selectively incorporated into cardiac cell membranes from the diet in a dose-related manner. Regular intake can slow the heart rate, reduce myocardial oxygen consumption, and increase coronary reserve. These properties contribute to preconditioning-like effects of ... |
8,265 | [Thyrometabolic disorders and heart failure]. | Thyroid hormones are essential to maintain normal function of many systems including the cardiovascular system. Their excess or deficiency may upset human body homeostasis. Hyperthyroidism leads to cardiovascular system's hyperdynamic status which is characterized by tachycardia, increased difference between systolic a... |
8,266 | Enhanced dispersion of atrial refractoriness as an electrophysiological substrate for vulnerability to atrial fibrillation in patients with paroxysmal atrial fibrillation. | Atrial electrical remodeling plays a part in recurrence of atrial fibrillation (AF). It has been related to an increase in heterogeneity of atrial refractoriness that facilitates the occurrence of multiple reentry wavelets and vulnerability to AF.</AbstractText>To examine the relationship between dispersion of atrial r... |
8,267 | Are maximum P wave duration and P wave dispersion a marker of target organ damage in the hypertensive population? | High blood pressure, left ventricular hypertrophy and diastolic dysfunction may cause hemodynamic and morphological changes in the left atrium, consequently instability and heterogeneity in atrial conduction. This is seen as an increase in maximum P wave duration (P(max)) and P wave dispersion (PD) on the electrocardio... |
8,268 | Awareness of guidelines for use of automated external defibrillators in children within emergency medical services. | Ventricular fibrillation occurs in 10-20% of pediatric cardiac arrests. Survival rates in children with ventricular fibrillation can be as high as 30% when the rhythm is identified and treated promptly. In the last 5 years, recommendations have been made for the use of automated external defibrillators in children betw... |
8,269 | Clinical experience with a low-energy pulsed biphasic waveform in out-of-hospital cardiac arrest. | The efficiency of a pulsed biphasic waveform (PBW) was compared with that of biphasic truncated exponential (BTE) waveforms. First defibrillation shock outcome was studied in a population of 104 out-of-hospital cardiac arrest patients in ventricular fibrillation as the presenting rhythm. The call to first shock time wa... |
8,270 | Is there a role for remodeled connexins in AF? No simple answers. | Gap junctions provide direct cytoplasmic continuity between cells forming a low resistivity barrier to electrical propagation. As such, aberrant regulation of these low resistive conduits has been blamed for electrical conduction disorders in diseased myocardium. While there is a plethora of evidence that abnormalities... |
8,271 | Phenotypic spectrum and clinical characteristics of apical hypertrophic cardiomyopathy: multicenter echo-Doppler study. | The aim of this study was to define the phenotypic spectrum of apical hypertrophic cardiomyopathy (ApHCM) and clinical characteristics pertaining to identified subtypes.</AbstractText>In 182 consecutive ApHCM patients (58.9 +/- 11.2 years; 142 men) with left ventricular ejection fraction > or =50%, we measured end-d... |
8,272 | T5 spinal cord transection increases susceptibility to reperfusion-induced ventricular tachycardia by enhancing sympathetic activity in conscious rats. | We recently documented that paraplegia (T(5) spinal cord transection) alters cardiac electrophysiology and increases the susceptibility to ventricular tachyarrhythmias induced by programmed electrical stimulation. However, coronary artery occlusion is the leading cause of death in industrially developed countries and w... |
8,273 | Right atrial infarction, atrial arrhythmia and inferior myocardial infarction form a missed triad: a case report and review of the literature. | Atrial infarction is rarely diagnosed before death because of its characteristically subtle and nonspecific electrocardiographic findings. These findings may be overshadowed by changes associated with concomitant ventricular infarction. A case of right atrial infarction accompanied by inferior myocardial infarction wit... |
8,274 | Spatiotemporal relationship between intracellular Ca2+ dynamics and wave fragmentation during ventricular fibrillation in isolated blood-perfused pig hearts. | Normal "master-slave" relationship between the action potential (AP) and intracellular Ca2+ transient (Ca(i)T) is sometimes altered during ventricular fibrillation (VF). The nature of AP/Ca(i)T dissociation during VF and its role in inducing wavebreaks (WBs) remain unclear. We simultaneously mapped AP (RH237) and Ca(i)... |
8,275 | Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue. | Ventricular fibrillation is a lethal condition caused by multiple chaotically wandering electrical wavelets in the heart, reentering their own and each other's territories. The development of effective therapies requires a detailed understanding of how these reentrant waves are initiated. In this Letter, we demonstrate... |
8,276 | Noncompaction and neuromuscular disease with positive troponin-T in a nonagenerian. | In a 94-year-old male with a history of atrial fibrillation, aortic stenosis, heart failure, apical thrombus, arterial hypertension, aneurysm of the abdominal aorta, and a urinary bladder carcinoma, cardiologic investigations revealed pulmonary rales, enlarged heart, absolute arrhythmia, and positive troponin-, myocard... |
8,277 | Strict versus moderate glucose control after resuscitation from ventricular fibrillation. | Elevated blood glucose is associated with poor outcome in patients resuscitated from out-of-hospital cardiac arrest (OHCA). Our aim was to determine whether strict glucose control with intensive insulin treatment improves outcome of OHCA patients.</AbstractText>A randomized, controlled trial.</AbstractText>Two universi... |
8,278 | [Patch angioplasty for superior vena cava syndrome after pacemaker implantation and maze procedure for chronic atrial fibrillation; report of a case]. | In 1984, the patient, a 68-year-old male, underwent pacemaker implantation for the treatment of sick sinus syndrome. Because of a postoperative pocket infection, the atrial lead was removed ; but it was difficult to extract the ventricular lead, which was therefore left in place. While under observation, transient faci... |
8,279 | Effect of electrode surface area on thresholds for AC stimulation and ventricular fibrillation. | Unintended, weak AC stimulation (leakage currents) from medical devices can cause blood pressure collapse and ventricular fibrillation (VF), potentially even death. Yet, little is understood about AC cardiac stimulation. The objective of this paper is to establish the relationship between the stimulation and VF thresho... |
8,280 | In-hospital arrhythmias in patients with acute myocardial infarction - the relation to the reperfusion strategy and their prognostic impact. | Arrhythmias are frequent complication in patients with acute myocardial infarction (MI). The importance of accelerated idioventricular rhythm (AIVR), ventricular fibrillation or tachycardia (VF, VT), atrial fibrillation or flutter (AF) and bradycardias is considered and discussed in this review article. The value of th... |
8,281 | Obstructive hypertrophic cardiomyopathy is associated with enhanced thrombin generation and platelet activation. | To investigate the association of left ventricular outflow tract (LVOT) obstruction with blood coagulation, platelet activity and inflammatory response in patients with hypertrophic cardiomyopathy (HCM) and sinus rhythm.</AbstractText>In 42 patients with HCM with sinus rhythm, including 16 patients with resting LVOT ob... |
8,282 | Impact of atrial fibrillation in heart failure with normal ejection fraction: a clinical and echocardiographic study. | The clinical significance of atrial fibrillation (AF) in heart failure with normal ejection fraction (HFNEF) remains undetermined.</AbstractText>We compared the clinical and echocardiographic characteristics among 238 patients hospitalized for HF. Using the cutoff of left ventricular EF of 50%, there were 146 patients ... |
8,283 | [Early and middle outcomes of total arterial revascularization using exclusively internal mammary artery and radial artery]. | To evaluate the early and mid-results of the use of the radial artery alongside the internal mammary artery for complete arterial revascularization in coronary bypass surgery.</AbstractText>From January 1999 to January 2005, 123 patients with coronary artery disease with lesions in more than one branch (target vessel),... |
8,284 | Electric field perturbations of spiral waves attached to millimeter-size obstacles. | Reentrant spiral waves can become pinned to small anatomical obstacles in the heart and lead to monomorphic ventricular tachycardia that can degenerate into polymorphic tachycardia and ventricular fibrillation. Electric field-induced secondary source stimulation can excite directly at the obstacle, and may provide a me... |
8,285 | [Electrical storm]. | Electrical storm is defined as repeated occurrence of severe ventricular arrhythmias requiring multiple cardioversions, two or more or three or more following different studies. The clinical aspect can sometimes be made of multiple, self aggravating, life threatening accesses. There are three main clinical circumstance... |
8,286 | Prognostic value of exercise tolerance testing in asymptomatic chronic nonischemic mitral regurgitation. | In many heart diseases, exercise tolerance testing (ETT) has useful functional correlates and/or prognostic value. However, its predictive value in mitral regurgitation (MR) is undefined. To determine whether ETT descriptors predict death or indications for mitral valve surgery in patients with MR, we prospectively fol... |
8,287 | Comparison of Afro-Caribbean patients presenting in heart failure with normal versus poor left ventricular systolic function. | Data suggest that heart failure (HF) in Afro-Caribbean patients may be more often associated with preserved left ventricular (LV) systolic function, LV hypertrophy, and probable LV diastolic dysfunction than in other populations. Echocardiographic results on all patients referred for HF in a contemporary Afro-Caribbean... |
8,288 | Near miss sudden cardiac death on a young patient with repaired atrioventricular septal defect. | Patients with congenital heart disease often face the prospect of long-term haemodynamic or arrhythmic complications for which lifelong follow-up in specialist adult congenital heart disease (ACHD) centres is required. We describe the case of a 25-year-old man with repaired atrioventricular septal defect who was referr... |
8,289 | Preoperative clinical status but not waiting time predicts in-hospital outcomes of surgery in patients with left main coronary artery stenosis. | Contoversy exists about the optimal operation time of the patients with left main coronary artery (LMCA) stenosis. We therefore, aimed to investigate the effect of waiting time on in-hospital morbidity and mortality in patients with LMCA stenosis and identify the risk factors associated with adverse cardiovascular even... |
8,290 | Therapeutic trial of granulocyte-colony stimulating factor for dilated cardiomyopathy in three dogs. | Three dogs were presented to us for evaluation of cardiac problems. Electrocardiographic recordings revealed severe tachyarrhythmia and atrial fibrillation with ventricular tachycardia in 2 of the 3 dogs. The echocardiographic findings of the 3 dogs revealed markedly decreased fractional shortening and a marked increas... |
8,291 | The transmural activation sequence in porcine and canine left ventricle is markedly different during long-duration ventricular fibrillation. | Humans are more similar in transmural Purkinje and cardiac ion channel distributions to dogs than pigs. The Purkinje network in pigs is transmural but confined to the endocardium in dogs. Little is known about intramural activation during long-duration ventricular fibrillation (LDVF) given these differences. We tested ... |
8,292 | Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome. | Macroscopic T-wave alternans (TWA) is sometimes observed after sodium channel blocker administration in patients with Brugada syndrome (BS), but little is known about the association between occurrence of TWA and clinical characteristics in BS patients. We investigated the association between spontaneous ventricular fi... |
8,293 | Early recurrence of ventricular fibrillation after successful defibrillation during prolonged global ischemia in isolated rabbit hearts. | The mechanisms that lower the efficacy of electrical defibrillation during prolonged global ischemia remain unclear.</AbstractText>Epicardial activation patterns during attempted electrical defibrillation were studied in 18 Langendorff-perfused rabbit hearts at baseline, after 5-minute no-flow global ischemia and after... |
8,294 | Azimilide for the treatment of atrial fibrillation, atrial flutter, and paroxysmal supraventricular tachycardia: results of a randomized trial and insights on the concordance of symptoms and recurrent arrhythmias. | Azimilide hydrochloride is an investigational antiarrhythmic medication that had shown evidence of efficacy in prolonging the time to recurrence of atrial fibrillation (AF) or atrial flutter (AFL) and paroxysmal supraventricular tachycardia (PSVT). This study was designed to confirm efficacy of 125 mg daily azimilide.<... |
8,295 | A pilot study in hemodialysis of an electrophysiological tool to measure sudden cardiac death risk. | The hemodialysis procedure may play a role in the elevated risk of sudden cardiac death seen in hemodialysis patients.</AbstractText>Microvolt T wave alternans, a promising noninvasive electrophysiological test developed to measure sudden cardiac death risk, was used to test the hypotheses that high-risk hemodialysis p... |
8,296 | Modelling of the ventricular conduction system. | The His-Purkinje conduction system initiates the normal excitation of the ventricles and is a major component of the specialized conduction system of the heart. Abnormalities and propagation blocks in the Purkinje system result in abnormal excitation of the heart. Experimental findings suggest that the Purkinje network... |
8,297 | [Clinical, echocardiographic and prognostic evaluation of atrial fibrillation in patients with heart failure]. | We aimed to assess the prevalence of atrial fibrillation (AF) in a general heart failure (HF) population admitted to a HF unit, analyze the parameters associated with AF, and evaluate its prognostic significance.</AbstractText>389 patients, 64 with AF at the first visit. Mean (SD) age was 65.38 (10.77) years and 72.5% ... |
8,298 | Angiotensin II type 1 receptor inhibition is associated with reduced tachyarrhythmia-induced ventricular interstitial fibrosis in a goat atrial fibrillation model. | Using a goat animal model, we tested the hypothesis that angiotensin-II inhibition reduces fibrotic degeneration of both the atrial and ventricular myocardium as well as AF induction susceptibility.</AbstractText>We studied three groups of five goats over a 6-month period. The study animals in the first two groups were... |
8,299 | Decreased right and left ventricular myocardial performance in obstructive sleep apnea. | Obstructive sleep apnea (OSA) may predispose patients to congestive heart failure (CHF), suggesting a deleterious effect of OSA on myocardial contractility.</AbstractText>A cross-sectional study of 85 subjects with suspected OSA who had undergone their first overnight polysomnogram, accompanied by an echocardiographic ... |
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