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8,100 | Survival after transcoronary ablation of septal hypertrophy in hypertrophic obstructive cardiomyopathy (TASH): a 10 year experience. | Catheter-based treatment of patients with hypertrophic obstructive cardiomyopathy (HOCM) by alcohol ablation (transcoronary ablation of septal hypertrophy, TASH) leads to symptomatic and haemodynamic improvement. However, little is known regarding the survival and its evolution since the introduction of the method in 1... |
8,101 | Effectiveness of bystander-initiated cardiac-only resuscitation for patients with out-of-hospital cardiac arrest. | Previous animal and clinical studies suggest that bystander-initiated cardiac-only resuscitation may be superior to conventional cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrests. Our hypothesis was that both cardiac-only bystander resuscitation and conventional bystander CPR would improve outcome... |
8,102 | Exercise oscillatory ventilation: instability of breathing control associated with advanced heart failure. | Instability of breathing control due to heart failure (HF) manifests as exercise oscillatory ventilation (EOV). Prior descriptions of patients with EOV have not been controlled and have been limited to subjects with left ventricular ejection fraction (LVEF) of <or= 0.40. The aim of this study was to compare clinical... |
8,103 | Repair of aortic arch and the impact of cross-clamping time, New York Heart Association stage, circulatory arrest time, and age on operative outcome. | Aortic arch replacement is associated with high morbidity and mortality.</AbstractText>We evaluated the postoperative complications and risk factors in 32 consecutive patients after aortic arch replacement.</AbstractText>The mean age was 61+/-15 years and male to female ratio was 24/8. Diameter of ascending aorta was 6... |
8,104 | [Prevalence and risk factors of atrial tachyarrhythmia before and after percutaneous closure of secundum atrial septal defect in patients over 40 years of age]. | In this study, we attempted to observe the prevalence and risk factors of atrial tachyarrhythmias (AT) before and after transcatheter closure of atrial septal defect (ASD).</AbstractText>264 adult patients aged over 40 years (67 men and 197 women) who underwent transcatheter closure of ASD between September, 1997 and D... |
8,105 | Deglutition induced atrial tachycardia and atrial fibrillation. | Deglutition induced supraventricular tachycardia is an uncommon condition postulated to be a vagally mediated phenomenon due to mechanical stimulation. Patients usually present with mild symptoms or may have severe debilitating symptoms. Treatment with Class I agents, beta blockers, calcium channel blockers, amiodarone... |
8,106 | Pseudo crosstalk behavior in a patient with atrio-ventricular block and implanted biventricular defibrillator. | We present a 59-year-old man with a dilated cardiomyopathy (ejection fraction = 20%), congestive heart failure and atrio-ventricular (AV) block who underwent implantation of a biventricular defibrillator (BiV ICD). While undergoing cardiac transplant evaluation for drug-refractory ventricular fibrillation, his telemetr... |
8,107 | Two cases of short QT interval. | The epidemiology of short QT interval remains unclear. We attempted to determine the incidence and clinical characteristics of short QT interval in a longitudinal cohort study.</AbstractText>A total of 19,153 subjects (7,525 male, 11,628 female) were enrolled in the study and all available electrocardiograms (ECGs) wer... |
8,108 | Morphology-enhanced atrial event classification improves sensing in pacemakers. | In atrial-based pacing, appropriate therapy and reliable diagnostics depend on detection and discrimination of atrial signals. Accurate classification of atrial events is mainly confounded by oversensing of ventricular far-field R-wave signals (FFRW), but attempts to reject FFRWs by manipulating atrial sensitivity and/... |
8,109 | Noradrenaline reduces ischemia-induced arrhythmia in anesthetized rats: involvement of alpha1-adrenoceptors and mitochondrial K ATP channels. | We have evaluated the part played by the mitochondrial ATP-sensitive potassium (mK(ATP)) channels on effect of alpha(1)-adrenoceptor activation by noradrenaline in ischemia-induced ventricular arrhythmia.</AbstractText>Anesthetized rats were subjected to 25 minutes of regional ischemia, and infarct size (IS) and ischem... |
8,110 | [The clinical challenge of the atrial fibrillation]. | Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. It consists in the triggering of 300 to 600 atrial waves per minute. The ventricular rate depends of the AV node refractory period that without treatment it is very high. This rapid response reduces the ventricular filling period wit... |
8,111 | [New strategies in the treatment of atrial fibrillation]. | Atrial fibrillation (AFb) is the most common sustained cardiac arrhythmia. Once initiated, AFb alters atrial electrical and structural properties (remodeling) that promotes its maintenance and recurrence. Treatment is directed to restore and maintain the sinus rhythm, to control the ventricular rate and to prevent thro... |
8,112 | Detection of phase singularities in triangular meshes. | Phase singularities have become a key marker in animal and computer models of atrial and ventricular fibrillation. However, existing algorithms for the automatic detection of phase singularities are limited to regular, quadratic mesh grids. We present an algorithm to automatically and exactly detect phase singularities... |
8,113 | Electromagnetic modelling of current flow in the heart from TASER devices and the risk of cardiac dysrhythmias. | Increasing use by law enforcement agencies of the M26 and X26 TASER electrical incapacitation devices has raised concerns about the arrhythmogenic potential of these weapons. Using a numerical phantom constructed from medical images of the human body in which the material properties of the tissues are represented, comp... |
8,114 | Sinus node disease and arrhythmias in the long-term follow-up of former professional cyclists. | Significant brady- and tachyarrhythmias may occur in active endurance athletes. It is controversial whether these arrhythmias do persist after cessation of competitive endurance training.</AbstractText>Among all 134 former Swiss professional cyclists [hereafter, former athletes (FAs)] participating at least once in the... |
8,115 | Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin. | The resveratrol-induced cardiac protection was studied in Zucker obese rats. Rats were divided into five groups: group 1, lean control; group 2, obese control (OC); group 3, obese rats treated orally with 5 mg kg(-1) day(-1) of resveratrol (OR) for 2 wk; group 4, obese rats received 10% glucose solution ad libitum for ... |
8,116 | Altered expression of connexin43 contributes to the arrhythmogenic substrate during the development of heart failure in cardiomyopathic hamster. | Heart failure is known to predispose to life-threatening ventricular tachyarrhythmias even before compromising the systemic circulation, but the underlying mechanism is not well understood. The aim of this study was to clarify the connexin43 (Cx43) gap junction remodeling and its potential role in the pathogenesis of a... |
8,117 | Driving and implantable cardioverter-defibrillator shocks for ventricular arrhythmias: results from the TOVA study. | This study examined the risk of implantable cardioverter-defibrillator (ICD) shocks for ventricular tachycardia (VT) or ventricular fibrillation (VF) associated with driving.</AbstractText>Concerns regarding VT/VF occurring during driving are the basis for driving restrictions in ICD patients; however, limited data are... |
8,118 | Catheter ablation of atrial fibrillation. | Atrial fibrillation is a common arrhythmia associated with significant morbidity including angina, heart failure and stroke. Medical therapy remains suboptimal with significant side effects and toxicities, as well as a high recurrence rate. Catheter ablation or modification of the atrio-ventricular node with pacemaker ... |
8,119 | The role of pacemakers in the management of patients with atrial fibrillation. | Pacemakers have an important role in the major strategies for the management of atrial fibrillation, rate control and rhythm control. Of all the current non-pharmacologic therapies for atrial fibrillation, the use of pacemakers impacts the largest number of patients. Pacemakers are used to facilitate medical management... |
8,120 | Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP. | Parasympathetic stimulation of the heart, which provides protection from arrhythmias and sudden death, involves activation of the G protein-coupled inward rectifying K+ channel GIRK1/4 and results in an acetylcholine-sensitive K+ current, I KACh. We describe a unique relationship between lipid homeostasis, the lipid-se... |
8,121 | Simultaneous multi-vessel coronary artery bypass grafting, ischemic mitral regurgitation repair and descending aortic aneurysm replacement: analysis of technical points. | The combination of coronary artery disease and its complications (ischemic mitral regurgitation etc.) with the aneurysm of the descending thoracic aorta is not a rare case. The single-stage correction of coronary/intracardiac/aortic lesions may be considered as a way of managing the combined patients. Simultaneous mult... |
8,122 | Effect of heterogeneous APD restitution on VF organization in a model of the human ventricles. | The onset of ventricular fibrillation (VF) has been associated with steep action potential duration restitution in both clinical and computational studies. Recently, detailed clinical restitution properties in cardiac patients were reported showing a substantial degree of heterogeneity in restitution slopes at the epic... |
8,123 | In silico study on the effects of IKur block kinetics on prolongation of human action potential after atrial fibrillation-induced electrical remodeling. | Pharmacological treatment with various antiarrhythmic agents for the termination or prevention of atrial fibrillation (AF) is not yet satisfactory. This is in part because the drugs may not be sufficiently selective for the atrium, and they often cause ventricular arrhythmias. The ultrarapid-delayed rectifying potassiu... |
8,124 | Spontaneous stellate ganglion nerve activity and ventricular arrhythmia in a canine model of sudden death. | Little information is available on the temporal relationship between instantaneous sympathetic nerve activity and ventricular arrhythmia in ambulatory animals.</AbstractText>The purpose of this study was to determine if increased sympathetic nerve activity precedes the onset of ventricular arrhythmia.</AbstractText>Sim... |
8,125 | Acute defibrillation performance of a novel, non-transvenous shock pathway in adult ICD indicated patients. | The purpose of this study was to evaluate the efficacy of a totally subcutaneous, anteroposterior defibrillation shock pathway using a long time-constant shock waveform that emulates a proposed device having approximately twice the capacitance and thus twice the available energy of traditional transvenous devices.</Abs... |
8,126 | Cardiac remodeling and predictors for cardiac death in long-term follow-up of subjects with chronic Chagas' heart disease: a mathematical model for progression of myocardial damage.<Pagination><StartPage>435</StartPage><EndPage>438</EndPage><MedlinePgn>435-8</MedlinePgn></Pagination><Abstract><AbstractText>In a prospec... | In a prospective longitudinal study the occurrence of cardiac death was investigated and ongoing cardiac remodeling retrospectively analyzed in regard to adverse outcome. A cohort of 50 subjects with chronic Chagas' disease stratified according to Los Andes groups 1, 2 and 3 were followed-up for (mean+/-SD) 84.2+/-39.0... |
8,127 | Propagation velocity kinetics and repolarization alternans in a free-behaving sheep model of pacing-induced atrial fibrillation. | Experimental models have reported conflicting results regarding the role of dispersion of repolarization in promoting atrial fibrillation (AF). Repolarization alternans, a beat-to-beat alternation in action potential duration, enhances dispersion of repolarization when propagation velocity is involved.</AbstractText>In... |
8,128 | Influence of diffuse fibrosis on wave propagation in human ventricular tissue. | During ageing, after infarction, in cardiomyopathies and other cardiac diseases, the percentage of fibrotic (connective) tissue may increase from 6% up to 10-35%. The presence of increased amounts of connective tissue is strongly correlated with the occurrence of arrhythmias and sudden cardiac death.</AbstractText>In t... |
8,129 | The Brugada syndrome in Canada: a unique French-Canadian experience. | The Brugada syndrome (BS) is a clinical entity involving cardiac sodium channelopathy, typical electrocardiogram (ECG) changes and predisposition to ventricular arrhythmia. This syndrome is mainly recognized by specialized cardiologists and electrophysiologists. Data regarding BS largely come from multicentre registrie... |
8,130 | Catheter ablation for cardiac arrhythmias: a 14-year experience with 5330 consecutive patients at the Quebec Heart Institute, Laval Hospital. | Catheter ablation is a curative treatment with excellent success and minimal complication rates for patients with supraventricular or ventricular arrhythmias.</AbstractText>The acute outcomes and complications of all catheter ablation procedures for supraventricular and ventricular arrhythmias performed at the Quebec H... |
8,131 | Electrical heart disease: Genetic and molecular basis of cardiac arrhythmias in normal structural hearts. | Purely electrical heart diseases, defined by the absence of any structural cardiac defects, are responsible for a large number of sudden, unexpected deaths in otherwise healthy, young individuals. These conditions include the long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia and ... |
8,132 | Non-pharmacological management of ventricular tachycardia. | Ventricular tachyarrhythmias (VTA), a major cause of sudden cardiac death, require meticulous management in order to prevent recurrent episodes. Recently, non-pharmacological interventions, including radiofrequency catheter ablation and implantable cardioverter defibrillators (ICD), have become important treatments of ... |
8,133 | Drug therapy for ventricular tachyarrhythmia in heart failure. | Sudden cardiac death (SCD) accounts for approximately one-third of all deaths in patients with heart failure, and is generally the result of ventricular tachycardia (VT) and/or ventricular fibrillation (VF). The mechanisms of VT/VF associated with heart failure are complex and heterogeneous; they include functional and... |
8,134 | Brugada syndrome in Japan. | The incidence of Brugada syndrome (BS) is relatively high in Japan compared with the rest of the world, ranging between 0.1% and 0.2% in the general population. BS in Japan, as in other countries, is most prevalent in middle-aged men, and has characteristics ECG changes, a high recurrence rate in symptomatic patients, ... |
8,135 | Mechanism and new findings in Brugada syndrome. | Brugada syndrome is a clinical entity characterized by coved type ST-segment elevation in the right precordial electrocardiographic leads (V(1-3)) and an episode of ventricular fibrillation in the absence of structural heart disease. Although a number of clinical and experimental reports have elucidated the electrocard... |
8,136 | Modulation of spiral wave reentry by K(+) channel blockade. | It is well established that spiral wave reentry is the primary mechanism of ventricular tachyarrhythmias (ventricular fibrillation/tachycardia, VF/VT), but information is still limited concerning pharmacological modification of spiral waves by ion channel blockers. In this brief review, the antiarrhythmic and proarrhyt... |
8,137 | Risk stratification for sudden cardiac death. | Sudden cardiac death (SCD) is a leading cause of mortality in industrialized countries, and ventricular fibrillation and sustained ventricular tachycardia are the major causes of SCD. Although there are now effective devices and medications that can prevent such serious arrhythmias, it is crucial to have methods of ide... |
8,138 | Ventricular fibrillation: dynamics and ion channel determinants. | Ventricular fibrillation (VF) is the leading cause of sudden cardiac death. This brief review addresses issues relevant to the dynamics of the rotors responsible for functional reentry and VF. It also makes an attempt to summarize present-day knowledge of the manner in which the dynamic interplay between inward and out... |
8,139 | Electrotonic remodeling following myocardial infarction in dogs susceptible and resistant to sudden cardiac death. | Passive electrical remodeling following myocardial infarction (MI) is well established. These changes can alter electrotonic loading and trigger the remodeling of repolarization currents, a potential mechanism for ventricular fibrillation (VF). However, little is known about the role of passive electrical markers as to... |
8,140 | Effects of dual endothelin receptor blockade on sympathetic activation and arrhythmogenesis during acute myocardial infarction in rats. | The effects of dual (ETA and ETB) endothelin receptor blockade on ventricular arrhythmogenesis during acute myocardial infarction are not well defined. We randomly allocated Wistar rats to bosentan (100 mg/kg daily, n=24), a dual endothelin receptor antagonist, or vehicle (n=23). After 7 days of treatment, myocardial i... |
8,141 | Catheter-ablation of ventricular tachycardia in patients with coronary artery disease: influence of the endocardial substrate size on clinical outcome. | Ablation of symptomatic ventricular tachycardia (VT) in patients with coronary artery disease is frequently performed using the three dimensional mapping system CARTO. In the amplitude map, bipolar potentials of <1.5 mV are considered abnormal and represent damaged myocardium due to previous infarction. This patholo... |
8,142 | Emergency department use of intravenous procainamide for patients with acute atrial fibrillation or flutter. | Acute atrial fibrillation and flutter are very common arrhythmias seen in emergency department (ED) patients, but there is no consensus for their optimal management. The objective of this study was to examine the efficacy and safety of intravenous (IV) procainamide for acute atrial fibrillation or flutter.</AbstractTex... |
8,143 | Pre-transplant predictors of cerebrovascular events after kidney transplantation. | We evaluated cerebrovascular events (CVE) after kidney transplantation (KTx) and sought to identify pre-transplant predictors of transient ischaemic attacks (TIA) and strokes post-transplantation.</AbstractText>A total of 1617 consecutive kidney and 16 kidney-pancreas recipients transplanted between 1995 and 2005 were ... |
8,144 | [Influence of the radiofrequency current on the left ventricular systolic function]. | Radio frequency catheter ablation (RFCA)--induced myocardial injury is caused by the thermal, electrical and biological effects of RF current.</AbstractText>To assess the changes in the left ventricular systolic function following RFCA.</AbstractText>Ejection fraction (EF) and shortening fraction (FS) were assessed in ... |
8,145 | Relationship between serum magnesium level and arrythmias following post-coronary artery bypass grafting. | Atrial and ventricular arrhythmias are among the most common complications after coronary artery bypass graft (CABG) surgery. It is known that cardiopulmonary bypass reduces serum magnesium level. In this study, we evaluated the relationship between total blood magnesium level (TMG) and the incidence of perioperative a... |
8,146 | Electrical storm: clinical manifestations and management. | Electrical storm is the clustering of hemodynamically destabilizing ventricular tachycardia or ventricular fibrillation that typically requires multiple electrical cardioversions or defibrillations within a 24-hour period. Electrical storm is frequently seen in the acute phase of myocardial infarction, in patients with... |
8,147 | Pulsatile versus nonpulsatile flow to maintain the equivalent coronary blood flow in the fibrillating heart. | How much flow is required by a nonpulsatile pump to match the coronary blood flow equivalent to that of pulsatile pump? A cardiopulmonary bypass circuit from the right atrium to the ascending aorta was constructed in a ventricular fibrillation model using 13 Yorkshire swine. The animals were randomly divided into two g... |
8,148 | Effects of combined sildenafil-nitric oxide donor on defibrillation efficacy. | A previous study demonstrated that supra-therapeutic concentration of sildenafil citrate attenuates defibrillation efficacy. However, the effect of combined sildenafil and NTG administration on defibrillation efficacy is not known.</AbstractText>The present study investigated whether sildenafil administration at the th... |
8,149 | Effect of epicardial fat on ablation performance: a three-energy source comparison. | To investigate the effect of epicardial fat on surgical atrial fibrillation ablation performance using an in vitro model. Two tissue models were employed to investigate standard penetration and maximal lesion depth performance of bipolar radiofrequency (RF), microwave, and laser energy sources.</AbstractText>Ventricula... |
8,150 | Interference of electrical dental equipment with implantable cardioverter-defibrillators. | To determine whether electromagnetic interference with implantable cardioverter-defibrilllators (ICDs) occurs during the use of electrical dental equipment.</AbstractText>Ten different electrical dental devices were tested for their ability to interfere with the function of three types of ICDs at different intervals fo... |
8,151 | Pilsicainide-induced Brugada-type ECG and ventricular arrhythmias originating from the left posterior fascicle in a case with Brugada syndrome associated with idiopathic left ventricular tachycardia. | The patient was a 50-year-old male in 2002, who was first suspected of having a Brugada-type electrocardiogram (ECG). A drug challenge test using pilsicainide was performed and unmasked a typical coved type ST elevation followed by ventricular arrhythmias (VAs) manifesting a QRS pattern with a right bundle branch block... |
8,152 | Rationale and design of a prospective study of the efficacy of a remote monitoring system used in implantable cardioverter defibrillator follow-up: the Lumos-T Reduces Routine Office Device Follow-Up Study (TRUST) study. | Increased implantable cardioverter defibrillator (ICD) implant volumes (and product advisories/recalls) pose management challenges. Most device interrogations at 3- to 6-month routine follow-up visits are "nonactionable," that is, require no clinically significant reprogramming, lead revision, or initiation or up-titra... |
8,153 | [Significance of the contralateral approach combined with venous deocclusion in a case of biventricular defibrillator implantation]. | The authors report the case of a patient in whom a biventricular defibrillator was successfully implanted from the right, following a failed approach from the left. The patient had chronic thrombosis of the subclavian vein, and this procedure was only possible after venous deocclusion and the positioning of an endopros... |
8,154 | [Echocardiographic factors predictive of restoration and maintenance of sinus rhythm after reduction of atrial fibrillation]. | Atrial fibrillation (AF) is the most common cardiac arrhythmia. While the arrhythmia was initially thought to be little more than a nuisance, it is now clear that AF has a significant negative impact on quality of life and a corresponding increase in both morbidity and mortality.</AbstractText>The aim of this study was... |
8,155 | [Evaluation of the cost of complications of automatic implantable defibrillators]. | The automatic implantable defibrillator (AID) has been shown to prevent sudden death but it frequently gives rise to complications. These complications seem to be costly but they do not figure in the economic assessments of AID. From 1989 to 2003, 202 patients (173 men, age 58 +/- 14 years) received consecutively 264 A... |
8,156 | Cardiac arrest and left ventricular fibrosis in a Finnish family with the lamin A/C mutation. | We screened the candidate genes from a Finnish family in which the mother was resuscitated from ventricular fibrillation and the daughter died suddenly without any prior cardiac symptoms.</AbstractText>In addition to screening of potential structural gene mutations, phenotyping of the proband and medico-legal autopsy o... |
8,157 | Prognostic value of 123I-metaiodobenzylguanidine in patients with various heart diseases. | It has been reported that (123)I-metaiodobenzylguanidine (MIBG) scintigraphy can predict the poor prognosis in patients with dilated cardiomyopathy (DCM). However, the prognostic significance of MIBG is still unknown in patients with other heart diseases. In this study, we compared the prognosis and MIBG findings in va... |
8,158 | Different effects of antiarrhythmic drugs on the rate-dependency of QT interval: a study with amiodarone and flecainide. | To describe the QT/RR relationship in normal subjects, a previous study validated experimentally and used in healthy subjects a function that separately considered rate-dependent and rate-independent components of ventricular repolarization. The analysis is now extended to the effects on the QT/RR relationship of amiod... |
8,159 | Aortic stenosis. | Patients with aortic stenosis (AS) have an increased prevalence of coronary risk factors, coronary artery disease, and other atherosclerotic vascular disease and an increased incidence of coronary events and death. Statins may reduce the progression of AS. Angina pectoris, syncope or near syncope, and heart failure are... |
8,160 | Predictors of paroxysmal atrial fibrillation in patients undergoing aortic valve replacement. | Atrial fibrillation is one of the most common complications after cardiac surgery. This study evaluates the risk factors of paroxysmal atrial fibrillation in patients who underwent aortic valve replacement.</AbstractText>The study comprised 300 patients with aortic valve defects of either aortic stenosis (n = 150) or r... |
8,161 | Characteristics of cardiac arrest and resuscitation by age group: an analysis from the Swedish Cardiac Arrest Registry. | The objective of this study was to describe patients who experienced an out-of-hospital cardiac arrest (OHCA) by age group.</AbstractText>All patients who suffered from an OHCA between 1990 and 2005 and are included in the Swedish Cardiac Arrest Registry (n = 40,503) were classified into the following age groups: neona... |
8,162 | [Cross-sectional study of heart failure of patients intaked in an Internal Medicine Service in the third level hospital in mixed area. Part III: mortality analysis]. | To establish the characteristics of the deceased in intaked patients by heart failure.</AbstractText>A cross-sectional study of the intaked patients in the Internal Medicine Service in the Hospital Clínico Universitario de Santiago de Compostela between 1999 to 2003. The variables analized were: sex, age, days of ... |
8,163 | Valvular heart disease: diagnosis and management. | Valvular heart disease is a leading cause of morbidity and mortality in India. Advances in both surgical and percutaneous techniques and a better understanding of timing for intervention accounts for the current increased rates of survival. Echocardiography remains the gold standard for diagnosis and periodic assessmen... |
8,164 | [QT dynamicity in risk stratification in patients after myocardial infarction]. | Ventricular repolarization abnormalities are associated with increased risk of sudden cardiac death in patients after myocardial infarction. The aim of this study is to assess QT dynamicity - QT/RR relationship - in patients after myocardial infarction and its contribution to risk stratification of sudden cardiac death... |
8,165 | [Early haemodynamic changes after radiofrequency ablation of the atrioventricular junction]. | The effect of radiofrequency ablation of the atrioventricular junction may be accompanied by undesired effect of right ventricular stimulation. The objective of the study was to evaluate early haemodynamic effects of catheter ablation in patients with permanent atrial fibrillation resistant to pharmacotherapy.</Abstrac... |
8,166 | ECG monitoring after cardiac surgery: postoperative atrial fibrillation and the atrial electrogram. | Atrial fibrillation is one of the most common complications after cardiac surgery and is associated with adverse outcomes such as increased mortality, neurological problems, longer hospitalizations, and increased cost of care. Major risk factors for the development of postoperative atrial fibrillation include older age... |
8,167 | Narrow QRS complex tachycardias. | Narrow QRS complex tachycardias are either atrioventricular (AV) nodal passive or AV nodal active. AV nodal passive tachycardias do not require the participation of the AV node in maintenance of the tachycardia. Examples are atrial tachycardia, atrial flutter, and atrial fibrillation. Treatment is directed at ventricul... |
8,168 | A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance. | Auditory stimulus-induced long QT syndrome (LQTS) is almost exclusively linked to mutations in the hERG potassium channel, which generates the I Kr ventricular repolarization current. Here, a young woman with prior episodes of auditory stimulus-induced syncope presented with LQTS and ventricular fibrillation (VF) with ... |
8,169 | New-onset heart failure after permanent right ventricular apical pacing in patients with acquired high-grade atrioventricular block and normal left ventricular function. | Emerging data have suggested that right ventricular (RV) apical pacing results in progressive left ventricular (LV) dysfunction and contributes to the development of heart failure (HF). This study aimed to investigate the prevalence and clinical predictors for the development of new-onset HF after long-term RV apical p... |
8,170 | Ventricular artifacts cancellation from atrial epicardial recordings in atrial tachyarrhythmias. | Atrial tachyarrhythmias are a very common cardiovascular disease in clinical practice with an incidence that doubles with each advancing decade. A key issue to understand their pathophysiological mechanisms is the analysis and interpretation of atrial electrograms (AEG). To properly study these signals, ventricular art... |
8,171 | Ventricular arrhythmias assessment. | An integrated framework for ventricular arrhythmias (VA) assessment, composed of two levels, is proposed in this work. The first level consists of four independent neural networks (NN), designed for specific detection tasks: signal quality, premature ventricular contractions (PVC), ventricular tachycardia (VT) and vent... |
8,172 | Cardiac arrhythmia detection by parameters sharing and MMIE training of Hidden Markov Models. | This paper is concerned to the cardiac arrhythmia classification by using Hidden Markov Models and Maximum Mutual Information Estimation (MMIE) theory. The types of beat being selected are normal (N), premature ventricular contraction (V), and the most common class of supra-ventricular arrhythmia (S), named atrial fibr... |
8,173 | The effect of internal DC shocks on the atrial fibrillation frequency. | The objective of this study, was to investigate the effect of internal DC shocks on the atrial fibrillation frequency (AFF). AFF has previously been shown to predict the success and energy requirements in patients undergoing internal cardioversion (IC) of atrial fibrillation (AF). However the possibility that unsuccess... |
8,174 | Non-linear organization analysis of paroxysmal atrial fibrillation. | Atrial fibrillation (AF) is a common supraventricular arrhythmia with episodes that, in the first stages of the disease, may terminate spontaneously. This fact is referred as paroxysmal atrial fibrillation. The analysis of its termination or maintenance could avoid unnecessary therapy and contribute to take the appropr... |
8,175 | Phase-rectified signal averaging: a useful tool for the estimation of the dominant frequency in ECG signals during atrial fibrillation. | Atrial fibrillation (AF) is the most common type of human cardiac arrhythmia. An important parameter that can be extracted from surface electrocardiogram (ECG) during AF is the dominant frequency (DF) of AF. Unfortunately, AF signal components are always highly contaminated by the ventricular QRST complexes, and the ca... |
8,176 | Arrhythmogenic right ventricular cardiomyopathy/dysplasia. | Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a heart muscle disease clinically characterized by life-threatening ventricular arrhythmias. Its prevalence has been estimated to vary from 1:2,500 to 1:5,000. ARVC/D is a major cause of sudden death in the young and athletes. The pathology consists ... |
8,177 | Reducing events in patients with chronic heart failure (REDUCEhf ) study design: continuous hemodynamic monitoring with an implantable defibrillator. | The use of implantable cardioverter defibrillators (ICDs) has been proven effective in the prevention of sudden cardiac death (SCD) and constitutes standard of care in appropriate populations. Combining a pressure sensing system with ICD therapy represents the first attempt to provide continuous hemodynamic monitoring ... |
8,178 | Cardiomyocyte Ca2+ overload in atrial tachycardia: is blockade of L-type Ca2+ channels a promising approach to prevent electrical remodeling and arrhythmogenesis? | Electrical remodeling paradigm has important implications for the understanding of atrial fibrillation (AF) and improvement of current treatment. Cardiomyocyte Ca(2+) overload is generally accepted as the initiating signal for the tachycardia-induced changes in atrial electrical properties (electrical remodeling). The ... |
8,179 | The dependence of successful resuscitation on electrocardiographically documented cardiac rhythm in case of out-of-hospital cardiac arrest. | To determine the influence of electrocardiographically documented cardiac rhythm during sudden cardiac arrest on successful resuscitation among out-of-hospital deaths in Kaunas city.</AbstractText>An observational prospective study was conducted between 1 January, 2005, and 30 December, 2005, in Kaunas city with a popu... |
8,180 | Improved neurological outcome with continuous chest compressions compared with 30:2 compressions-to-ventilations cardiopulmonary resuscitation in a realistic swine model of out-of-hospital cardiac arrest. | The 2005 Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care changed the previous ventilations-to-chest-compression algorithm for bystander cardiopulmonary resuscitation (CPR) from 2 ventilations before each 15 chest compressions (2:15 CPR) to 30 chest compressions before 2 ventilations (30:2... |
8,181 | Predictors of arrhythmia recurrence in patients with lone atrial fibrillation. | The need for antiarrhythmic drugs (AAD) after a first episode of atrial fibrillation (AF) is determined by the probability of recurrence. The aim of this study was to asses the probability of relapse and the predictors of recurrence in patients with idiopathic AF.</AbstractText>A cohort of 98 consecutive patients young... |
8,182 | Influence of diabetes on cardiac resynchronization therapy with or without defibrillator in patients with advanced heart failure. | We performed a post hoc analysis to determine the influence of cardiac resynchronization therapy with a defibrillator (CRT-D) or without a defibrillator (CRT-P) on outcomes among diabetic patients with advanced heart failure (HF).</AbstractText>In patients with systolic HF, diabetes is an independent predictor of morbi... |
8,183 | Prognostic usefulness of anemia and N-terminal pro-brain natriuretic peptide in outpatients with systolic heart failure. | N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and anemia are predictors of outcome in systolic heart failure. It is currently unclear how these 2 markers interact in particular with regard to the prognostic information carried by each risk marker. We therefore tested the hypothesis that anemia (World Health Org... |
8,184 | Control of electrical alternans in simulations of paced myocardium using extended time-delay autosynchronization. | Experimental studies have linked alternans, an abnormal beat-to-beat alternation of cardiac action potential duration, to the genesis of lethal arrhythmias such as ventricular fibrillation. Prior studies have considered various closed-loop feedback control algorithms for perturbing interstimulus intervals in such a way... |
8,185 | Evaluating intramural virtual electrodes in the myocardial wedge preparation: simulations of experimental conditions. | While defibrillation is the only means for prevention of sudden cardiac death, key aspects of the process, such as the intramural virtual electrodes (VEs), remain controversial. Experimental studies had attempted to assess intramural VEs by using wedge preparations and recording activity from the cut surface; however, ... |
8,186 | Cellular basis for triggered ventricular arrhythmias that occur in the setting of compensated hypertrophy and heart failure: considerations for diagnosis and treatment. | Malignant ventricular tachyarrhythmias are common among patients with hypertrophy and heart failure, and these arrhythmias can initiate by triggered activity. Abnormal repolarization and disturbed calcium handling due to remodeling processes are common features of the hypertrophied and failing heart that conspire to fa... |
8,187 | Eight (or more) kinds of alternans. | Cardiac electrical alternans is an alternating rhythm in the electrical properties of the heart, such as cellular action potential duration, conduction velocity, and/or intracellular calcium (Ca) concentrations. These alternations can initiate reentrant arrhythmias and can also break up ongoing reentry, creating ventri... |
8,188 | Imaging fibrillation/defibrillation in a dish. | Sheets of cultured cardiac cells constitute an emerging experimental model of cardiac tissue electrophysiology and arrhythmia. It has been used to study fundamental properties of reentrant (spiral) waves and electric field interactions with tissue structure and thus constitutes a valuable model for investigations of fi... |
8,189 | Imaging ventricular fibrillation. | Ventricular fibrillation (VF) had been traditionally considered as a highly disorganized process of random electrical activity emanating from multiple, short-lived, reentrant electrical waves. It is the incessant breakup of wave fronts and the creation of new daughter waves (wavebreaks) that perpetuate VF. Other studie... |
8,190 | Cardiac electrical dynamics: maximizing dynamical heterogeneity. | The relationships between key features of the cardiac electrical activity, such as electrical restitution, discordant alternans, wavebreak, and reentry, and the onset of ventricular tachyarrhythmias have been characterized extensively under the condition of constant rapid pacing. However, it is unlikely that this scena... |
8,191 | Genetic predisposition and cellular basis for ischemia-induced ST-segment changes and arrhythmias. | Recent reports have highlighted the importance of a family history of sudden death as a risk for ventricular fibrillation (VF) in patients experiencing acute myocardial infarction (AMI), pointing to the possibility of a genetic predisposition. This report briefly reviews 2 recent studies designed to examine the hypothe... |
8,192 | Detection of cardiac tachyarrhythmias in implantable devices. | Implantable devices such as pacemakers and implantable cardioverter/defibrillators (ICDs) use algorithms to sense cardiac depolarizations and to detect tachyarrhythmias by analysis of timing and morphology of sensed events. The purpose of tachyarrhythmia detection in these devices is to guide electrical therapies deliv... |
8,193 | Full recovery of an avalanche victim with profound hypothermia and prolonged cardiac arrest treated by extracorporeal re-warming. | Survival of hypothermic avalanche victims with cardiac arrest is rare. This report describes full recovery of a 29-year-old backcountry skier completely buried for 100 min at 3.0m (9.8 ft) depth. On extrication he was unconscious, but breathing spontaneously into an air pocket; core body temperature measured 22.0 degre... |
8,194 | The tissue distribution of fluoride in a fatal case of self-poisoning. | The purpose of this paper is to report a case of fluoride poisoning along with a discussion of poisoning characteristics, analytical procedures, and a review of previous reports of fatal intoxications with analytical data. A case of suicidal ingestion of 40 mL of a rust removal agent containing hydrofluoric acid and am... |
8,195 | Percutaneous occlusion of patent ductus arteriosus with the Nit-Ccclud device in an adult patient. | We report a case of an adult patient with patent ductus arteriosus (PDA), a large aortic ampulla and moderate pulmonary hypertension. The PDA was successfully closed using a Nit-Occlud device designed for PDA closure. The day before the programmed procedure, the patient was admitted for signs and symptoms of cardiac he... |
8,196 | In vivo porcine model of reperfused myocardial infarction: in situ double staining to measure precise infarct area/area at risk. | The aim of this study is to evaluate a catheter-based porcine model for reperfused myocardial infarction and investigate the appropriate location and duration of the occlusion.</AbstractText>A balloon catheter was placed in the left descending coronary artery (LAD) in 78 swine, and used to occlude the LAD. To evaluate ... |
8,197 | Intracardiac thrombosis and embolism in patients with cardiac amyloidosis. | Patients with primary amyloidosis (AL type) have a poor prognosis, in part due to frequent cardiac involvement. Although intracardiac thrombus has been reported in anecdotal cases, neither its frequency nor its role in causing mortality is known. Furthermore, the clinical and echocardiographic variables that may be ass... |
8,198 | Azithromycin/chloroquine combination does not increase cardiac instability despite an increase in monophasic action potential duration in the anesthetized guinea pig. | Prolongation of the electrocardiogram QT interval by some, but not all drugs, has been associated with increased incidence of sudden cardiac death. Current preclinical regulatory assays cannot discriminate the arrhythmia liability of these drugs. Consequently, many new medications that prolong the QT interval are not d... |
8,199 | Loss of luminal Ca2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death. | Different forms of ventricular arrhythmias have been linked to mutations in the cardiac ryanodine receptor (RyR)2, but the molecular basis for this phenotypic heterogeneity is unknown. We have recently demonstrated that an enhanced sensitivity to luminal Ca(2+) and an increased propensity for spontaneous Ca(2+) release... |
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