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8,300 | Is ward experience in resuscitation effort related to the prognosis of unexpected cardiac arrest? | The aim of this study was to investigate the outcome of patients of unexpected cardiac arrest initially resuscitated by first responders with dissimilar experiences under the support of cardiac arrest team (CAT).</AbstractText>All unexpected cardiac arrest patients receiving in-hospital resuscitation with the activatio... |
8,301 | Standard versus over-the-head cardiopulmonary resuscitation during simulated advanced life support. | Limited space can make rescuer position changes difficult during cardiopulmonary resuscitation (CPR). Over-the-head (OTH) CPR enables one rescuer to deliver chest compressions and ventilations without changing position. The aim of the present study was to evaluate quality of OTH versus standard CPR with bag-valve-mask ... |
8,302 | Recurrent life-threatening ventricular dysrhythmias associated with acute hydrofluoric acid ingestion: observations in one case and implications for mechanism of toxicity. | Hydrofluoric acid (HF) is a weak inorganic acid used for etching and as rust remover. Systemic toxicity is manifested as ventricular dysrhythmias. The mechanisms for these dysrhythmias are not well elucidated.</AbstractText>An 82-year-old woman ingested 8 ounces of 7% HF. Shortly after emergency department (ED) arrival... |
8,303 | Changes and predictive value of dispersion of repolarization parameters for appropriate therapy in patients with biventricular implantable cardioverter-defibrillators. | The impact of cardiac resynchronization therapy (CRT) on dispersion of repolarization is controversial. The benefit of CRT on sudden cardiac death has been demonstrated only after 3 years follow-up.</AbstractText>The purpose of this study was to explore the immediate effect of CRT on dispersion of repolarization and to... |
8,304 | Left ventricular dysfunction is associated with intraventricular dyssynchrony by 3-dimensional echocardiography in children. | We used 3-dimensional (3D) echocardiography to identify and quantify left ventricular (LV) dyssynchrony in children with LV dysfunction compared with control subjects.</AbstractText>The 3D echocardiography LV full volumes were acquired in 18 children, 9 with LV dysfunction and 9 control subjects. The LV was subdivided ... |
8,305 | Safety of stress echocardiography supervised by registered nurses: results of a 2-year audit of 15,404 patients. | Stress echocardiography has traditionally been performed under the supervision of physicians. In the last decade, at some institutions, specially trained registered nurses have taken on the task of directly supervising and conducting these stress tests with appropriate physician involvement and assistance.</AbstractTex... |
8,306 | Optimal noninvasive assessment of diastolic heart failure in patients with atrial fibrillation: comparison of tissue doppler echocardiography, left atrium size, and brain natriuretic peptide. | The aim of this study was to evaluate whether the ratio of early diastolic transmitral velocity to early diastolic mitral annular velocity (E/E') can be applied to identify diastolic heart failure (HF) noninvasively rather than using brain natriuretic peptide (BNP) or enlargement of left atrium (LA) in patients with at... |
8,307 | Selective cardiac plasma-membrane K(ATP) channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion. | ATP-dependent potassium channels (K(ATP)) have been implicated in cardioprotection both during myocardial ischemia and reperfusion. We compared the effect of a non-selective K(ATP) inhibitor glibenclamide, a selective mitochondrial K(ATP) inhibitor 5-hydroxy-decanoate (5-HD) and a selective sarcolemmal K(ATP) blocker H... |
8,308 | A study on pathogenesis of sudden death syndrome in broiler chickens. | Sudden death syndrome (SDS) in fast growing broiler chickens has been recognized as a patho-physiological entity for four decades, but its pathogenesis still remains unknown. More recent investigations provided evidence that link SDS to cardiac arrhythmia, but the mechanism triggering arrhythmogenesis and factors respo... |
8,309 | Impact of beating heart left atrial ablation on left-sided heart mechanics. | The cut-and-sew Cox-Maze procedure is the gold standard for surgical treatment of atrial fibrillation, but it is associated with long-term impairment of left atrial mechanical function. We developed a bipolar, irrigated radiofrequency ablation device. We hypothesized that beating heart radiofrequency left atrial ablati... |
8,310 | [Again new resuscitation guidelines (2006): justification, costs and potential confusion]. | The last revision of the Dutch resuscitation guidelines, a translation of the European Resuscitation Council Guidelines 2005, is based on the recommendations of the International Liaison Committee on Resuscitation (ILCOR). The previous Dutch guidelines were issued in 2002. Most changes are based on laboratory studies a... |
8,311 | Incidence of severe ventricular arrhythmias during pulmonary artery catheterization in liver allograft recipients. | Liver allograft recipients may develop a hyperdynamic circulation and cardiac electrophysiologic abnormalities. The incidence of severe ventricular arrhythmias in liver allograft recipients during pulmonary artery (PA) catheterization was determined. One hundred five liver allograft recipients were studied prospectivel... |
8,312 | Emergency preservation and resuscitation improve survival after 15 minutes of normovolemic cardiac arrest in pigs. | Outcome after prolonged normovolemic cardiac arrest is poor, and new resuscitation strategies have to be found. We hypothesized that the induction of deep hypothermia for emergency preservation and resuscitation (EPR) during prolonged cardiac arrest, before the start of reperfusion, will mitigate the deleterious cascad... |
8,313 | Predictors of all-cause mortality for patients with chronic Chagas' heart disease receiving implantable cardioverter defibrillator therapy. | Implantable Cardioverter Defibrillators (ICD) have sporadically been used in the treatment of either Sustained Ventricular Tachycardia (VT) or Ventricular Fibrillation (VF) in Chagas' disease patients. This study aimed at determining predictors of all-cause mortality for Chagas' disease patients receiving ICD therapy.<... |
8,314 | Clinical characteristics and risk stratification in symptomatic and asymptomatic patients with brugada syndrome: multicenter study in Japan. | Neither the clinical characteristics nor risk stratification in Brugada syndrome have been clearly determined. We compared the clinical and ECG characteristics of symptomatic and asymptomatic patients with Brugada syndrome to identify new markers for high-risk patients.</AbstractText>A total of 188 consecutive individu... |
8,315 | Influence of meals on variations of ST segment elevation in patients with Brugada syndrome. | Glucose-induced insulin secretion is one of the contributing factors to fluctuation of ST segment elevation in Brugada syndrome.</AbstractText>The purpose of this study was to explore the influence of meals on variations of ST elevation in Brugada syndrome.</AbstractText>We assessed changes of ST segment elevation in l... |
8,316 | Exacerbation of electrical storm subsequent to implantation of a right vagal stimulator. | A patient with advanced ischemic cardiomyopathy underwent implantation of a vagal stimulator in an attempt to control recurrent drug refractory ventricular arrhythmia. Electrical storm was exacerbated after the implant and continued after neurostimulation was discontinued. The report aims to provide a cautionary note t... |
8,317 | Treatment of heart failure with decreased left ventricular ejection fraction. | Class I recommendations for treating patients with current or prior symptoms of heart failure with reduced left ventricular ejection fraction (LVEF) include using diuretics and salt restriction in individuals with fluid retention. Use angiotensin-converting enzyme (ACE) inhibitors, beta blockers, and angiotensin II rec... |
8,318 | Outcome parameters for trials in atrial fibrillation: recommendations from a consensus conference organized by the German Atrial Fibrillation Competence NETwork and the European Heart Rhythm Association. | Atrial fibrillation (AF), the most common atrial arrhythmia, has a complex aetiology and causes relevant morbidity and mortality due to different mechanisms, including but not limited to stroke, heart failure, and tachy- or bradyarrhythmia. Current therapeutic options (rate control, rhythm control, antithrombotic thera... |
8,319 | Outcome parameters for trials in atrial fibrillation: executive summary. | Atrial fibrillation (AF), the most common atrial arrhythmia, has a complex aetiology and causes relevant morbidity and mortality due to different mechanisms, including but not limited to stroke, heart failure, and tachy- or bradyarrhythmia. Current therapeutic options (rate control, rhythm control, antithrombotic thera... |
8,320 | Brugada syndrome unmasked by accidental inhalation of gasoline vapors. | Loss-of-function mutations in the gene SCN5A can cause Brugada syndrome (BrS), which is an inherited form of idiopathic ventricular fibrillation. We report the case of a 46-year-old patient, with no previous medical history, who had ventricular fibrillation after accidental inhalation of gasoline vapors. His electrocar... |
8,321 | Effect of nifekalant for acute conversion of atrial flutter: the possible termination mechanism of typical atrial flutter. | Nifekalant is a class III antiarrhythmic drug, which is usually used for suppression of ventricular tachycardia (VT) and fibrillation. We studied the efficacy of nifekalant for acute conversion of atrial flutter (AFL) in a prospective, open label study in the intensive care unit (ICU) of cardiovascular medicine.</Abstr... |
8,322 | Hypertension and cardiac arrhythmias. | Arterial hypertension is a widespread disease and one of important yet under-recognized and under-treated causes of atrial and ventricular arrhythmias. Hypertrophy of cardiac muscle in hypertensive patients is characterized not only by increased myocardial mass, but also by proliferation of fibrous tissue and decreased... |
8,323 | Alterations in electrophysiology and tissue structure of the left atrial posterior wall in a canine model of atrial fibrillation caused by chronic atrial dilatation. | Chronic left atrial dilatation (CDLA) is associated with an increased incidence of atrial fibrillation (AF). The electrophysiological functions of the left atrial posterior wall (LAPW) are not well understood.</AbstractText>Eight control dogs and 8 with CDLA (developed 6 months after partial mitral valve avulsion) were... |
8,324 | Association of atrial arrhythmia and sinus node dysfunction in patients with catecholaminergic polymorphic ventricular tachycardia. | This study was performed to investigate the frequency and importance of supraventricular arrhythmia and sinus node (SN) dysfunction in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT).</AbstractText>Eight patients with CPVT (mean age: 16.8+/-8.1 years) underwent an electrophysiological study. ... |
8,325 | Ventricular fibrillation and defibrillation. | Cardiac arrest in children is not often due to a disturbance in rhythm that is amenable to electrical defibrillation, contrary to the situation in adults. When a shockable rhythm is present, defibrillation using an external electric shock applied at an early stage after pre-oxygenation and chest compressions is of prov... |
8,326 | Doppler-derived indexes and B-type natriuretic peptide in prediction of paroxysmal atrial fibrillation in essential hypertension: a prospective study. | Onset of atrial fibrillation in hypertensive patients is usually associated with a high occurrence of cardiovascular complications. Despite its leading importance as a highly prevalent and modifiable risk factor, only a few data are available regarding the predictors of paroxysmal atrial fibrillation (PAF) in hypertens... |
8,327 | Image integration in electroanatomic mapping. | Over the past five years, integration of the pre-procedural MR/CT images with a 3D electroanatomic mapping system has been developed to facilitate catheter ablation of clinical arrhythmias. It presents a significant advantage over the less-detailed surrogate geometry created by the 3D mapping systems. The process of im... |
8,328 | Effect of pravastatin on sympathetic reinnervation in postinfarcted rats. | We assessed whether pravastatin attenuates cardiac sympathetic reinnervation after myocardial infarction through the activation of ATP-sensitive K(+) (K(ATP)) channels. Epidemiological studies have shown that men treated with statins appear to have a lower incidence of sudden death than men without statins. However, th... |
8,329 | Permanent chronic atrial fibrillation: is pulmonary vein isolation alone enough? | The efficacy of mere pulmonary vein isolation epicardially for the treatment of permanent chronic atrial fibrillation, in comparison with the left atrial endocardial maze procedure was evaluated.</AbstractText>Retrospective data collection and analysis toward the outcome of 72 consecutive patients who underwent left at... |
8,330 | Breakdown of atheromatous plaque due to shear force from arterial perfusion cannula. | Breakdown of an atheromatous plaque in the aorta due to jet from the arterial cannula is reported. The patient underwent mitral valve replacement under ventricular fibrillation because of severe atheromatous change in the ascending aorta, transverse aortic arch, and descending aorta. A dispersive arterial perfusion can... |
8,331 | The herbal drug Catuama reverts and prevents ventricular fibrillation in the isolated rabbit heart. | Catuama, an herbal drug very popular in Brazil, was tested on the reversion and prevention of ventricular fibrillation (VF) in the isolated rabbit heart.</AbstractText>Catuama (a mixture of Trichilia catigua, Paullinia cupana, Ptychopetalum olacoides, and Zinziber officinalis) was perfused in the isolated perfused rabb... |
8,332 | Giant septal cavity due to coronary artery fistula and ventricular septal dissection after cardiac surgery. | Ventricular septal dissection may rarely result from infective endocarditis, myocardial infarction or sinus of Valsalva aneurysm progression. A rare case that developed in a 66-year-old female after mitral valve replacement for severe mitral regurgitation with cordal rupture is presented and discussed. It resulted from... |
8,333 | Relation between major and minor depression and heart rate, heart-rate variability, and clinical characteristics of patients with acute coronary syndrome. | This study examined the prevalence of major and minor depression in patients with acute coronary syndrome and their relation with heart rate and heart-rate variability, and clinical characteristics. The study group included 297 patients, 200 men and 97 women, between ages of 21 and 70 years (M age = 57.5 +/- 9.6), who ... |
8,334 | Circadian, daily, and seasonal distributions of ventricular tachyarrhythmias in patients with implantable cardioverter-defibrillators. | This study investigated the circadian, daily, and seasonal distributions of ventricular arrhythmias in patients with new implantable cardioverter-defibrillator placement at Creighton University Medical Center from January 2000 to December 2004. The incidence and distribution of ventricular tachyarrhythmias as recorded ... |
8,335 | Intermittent atrial sensing in a VDD pacemaker. | This report deals with a patient with single-lead VDD pacemaker and intermittent atrial sensing failure. At first glance, the electrocardiogram suggested a VVI mechanism of pacing, being paced QRS complexes dissociated from sinus P waves: this revealed that intracardiac atrial electrograms were too small to reach the s... |
8,336 | Cardiac transplantation in a patient with emotionally triggered implantable cardioverter defibrillator storms. | The implantable cardioverter defibrillator (ICD) may be responsible for psychological disorders especially among patients experiencing multiple shocks. An associated hyperadrenergic state (e.g., anger, anxiety) may trigger malignant ventricular arrhythmias repeatedly treated by ICD shocks, entertaining a "vicious circl... |
8,337 | Relation of interleukin-6 and C-reactive protein levels to sinus maintenance after pharmacological cardioversion in persistent atrial fibrillation. | The aim of this study was to investigate whether interleukin-6 (IL-6) and C-reactive protein (CRP) have significant relation to sinus maintenance after pharmacological conversion of long-lasting atrial fibrillation (AF) with respect to use of renin-angiotensin-aldosterone system (RAS) inhibitors.</AbstractText>We studi... |
8,338 | Prescribing amiodarone: an evidence-based review of clinical indications. | Although amiodarone is approved by the US Food and Drug Administration only for refractory ventricular arrhythmias, it is one of the most frequently prescribed antiarrhythmic medications in the United States.</AbstractText>To evaluate and synthesize evidence regarding optimal use of amiodarone for various arrhythmias.<... |
8,339 | Adjunctive therapy for recurrent ventricular tachycardia in patients with implantable cardioverter defibrillators. | Implantable cardioverter defibrillators (ICDs) are now the mainstay of therapy in patients with sustained ventricular tachycardia (VT), ventricular fibrillation, resuscitated sudden cardiac death, or certain high-risk markers for these arrhythmic events. Although ICDs in such patients can be life-saving, they can impai... |
8,340 | [Implications of gender-specific aspects in the therapy of cardiovascular diseases]. | In cardiovascular diseases e.g. heart failure and coronary artery disease gender differences are evident in etiology, pathophysiology, clinical presentation, prognosis and response to treatment. Diabetes and hypertension are the major risk factors in women. Mechanisms leading to apparent diabetes or its clinical pre-st... |
8,341 | Renal function is associated with risk of atrial fibrillation after cardiac surgery. | Atrial fibrillation (AF) frequently occurs after cardiac surgery and is responsible for increased morbidity and resource use. The aim of the present study was to evaluate the association of impaired renal function and the development of postoperative AF.</AbstractText>Patients undergoing elective cardiac surgery in the... |
8,342 | Efficacy of magnesium sulfate for treatment of ventricular tachycardia in amitriptyline intoxication. | In our country, tricyclic antidepressants are usually present in most of the homes. Myocardial depression and ventricular arrhythmia are the severe side effects in tricyclic antidepressant overdose. A 4-year-old boy was brought to our hospital after taking 70 mg/kg of amitriptyline. On arrival, the patient was comatose... |
8,343 | Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic features. | Catecholaminergic polymorphic ventricular tachycardia is a disease characterized by ventricular arrhythmias elicited exclusively under adrenergic stress. Additional features include baseline bradycardia and, in some patients, right ventricular fatty displacement. The clinical spectrum is expanded by the 2 families desc... |
8,344 | Conversion of atrial fibrillation to sinus rhythm during treatment with intravenous esmolol or diltiazem: a prospective, randomized comparison. | Prior studies have suggested that intravenous diltiazem reduces the probability of spontaneous conversion of atrial fibrillation (AF) to sinus rhythm in the electrophysiology laboratory and in patients with postoperative AF. Whether diltiazem exerts the same effect in patients presenting to the emergency department (ED... |
8,345 | Supernormal conduction in the anomalous bundles of the Wolff-Parkinson-White syndrome: an overlooked electrophysiologic property with potential clinical implications. | The anterograde refractory period (RP) of the accessory pathway (AP) is the main determinant factor of ventricular rate during atrial fibrillation in the Wolff-Parkinson-White (WPW) syndrome. We describe 3 examples of anterograde supernormal conduction (SNC) and 1 of retrograde SNC in APs. The paradoxical early recover... |
8,346 | Implantable cardioverter defibrillator therapy and the need for concomitant antiarrhythmic drugs. | Implantable cardioverter defibrillators (ICDs) are increasingly used for the prevention of sudden cardiac death in patients with life-threatening ventricular arrhythmias (VAs); however, there is a potential for severe and debilitating anxiety caused by symptoms associated with ICD therapy and anticipation of shocks. An... |
8,347 | Do patient characteristics or factors at resuscitation influence long-term outcome in patients surviving to be discharged following in-hospital cardiac arrest? | Few studies have focused on factors influencing long-term outcome following in-hospital cardiac arrest. The present study assesses whether long-term outcome is influenced by difference in patient factors or factors at resuscitation.</AbstractText>An analysis of cardiac arrest data collected from one Swedish tertiary ho... |
8,348 | Incessant non-sustained ventricular tachycardia after stimulus of electroconvulsive therapy with atropine premedication? | Electroconvulsive therapy (ECT) is an effective and safe treatment for a variety of neuropsychiatric disorders. Premedication with atropine has been recommended in order to avoid bradycardia and transient asystole induced by ECT. In contrast, some other arrhythmias can happen such as atrial flutter and fibrillation. Bu... |
8,349 | Differences in the characteristics of induced and spontaneous episodes of ventricular fibrillation. | The degree of organization of ventricular fibrillation (VF) can be examined in terms of the regularity of the electrical activity within the ventricle. Using electrograms (EGMs) stored within implanted cardioverter defibrillators (ICDs), we examined the hypothesis that the degree of organization, or regularity, was dif... |
8,350 | Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia. | Catecholaminergic polymorphic ventricular tachycardia (VT) is a lethal familial disease characterized by bidirectional VT, polymorphic VT, and ventricular fibrillation. Catecholaminergic polymorphic VT is caused by enhanced Ca2+ release through defective ryanodine receptor (RyR2) channels. We used epicardial and endoca... |
8,351 | A new cardiopulmonary resuscitation method using only rhythmic abdominal compression: a preliminary report. | This article introduces 2 new cardiopulmonary resuscitation (CPR) concepts: (1) the use of only rhythmic abdominal compression (OAC) to produce blood flow during CPR with ventricular fibrillation and (2) a new way of describing coronary perfusion effectiveness, namely, the area between the aortic and right atrial press... |
8,352 | Future directions in degenerative mitral valve repair. | Mitral valve repair is by far the most common operation for degenerative mitral regurgitation. If the procedure is performed before left ventricular dysfunction occurs and atrial fibrillation develops, the operative risk is very low and life expectancy is super imposable to that of the sex- and age-matched population. ... |
8,353 | Principles of reconstructive surgery in degenerative mitral valve disease. | Degenerative mitral valve disease is the most common cause of mitral regurgitation (MR) in developed countries. The most common etiologies of valvular regurgitation are Barlow's disease and fibroelastic deficiency. The mechanism of MR is type II dysfunction (leaflet prolapse) due to chordae elongation or rupture in mos... |
8,354 | Indications for surgery in degenerative mitral valve disease. | There has been great progress during the past decade in management of patients with mitral regurgitation. Doppler echocardiography allows accurate quantification of the degree of valve leakage and tracking of the effect of regurgitation on cardiac size and function. Natural history studies have clearly delineated the d... |
8,355 | Speckle-tracking radial strain reveals left ventricular dyssynchrony in patients with permanent right ventricular pacing. | Speckle-tracking strain analysis was used to assess the effects of permanent right ventricular (RV) pacing on the heterogeneity in timing of regional wall strain and left ventricular (LV) dyssynchrony.</AbstractText>Recent studies have shown detrimental effects of RV pacing, possibly related to the induction of LV dyss... |
8,356 | Limitations of ejection fraction for prediction of sudden death risk in patients with coronary artery disease: lessons from the MUSTT study. | We determined the contribution of multiple variables to predict arrhythmic death and total mortality risk in patients with coronary disease and left ventricular dysfunction. We then constructed an algorithm to predict risk of mortality and sudden death.</AbstractText>Many factors in addition to ejection fraction (EF) i... |
8,357 | Effects of epinephrine and vasopressin on cerebral microcirculatory flows during and after cardiopulmonary resuscitation. | Both epinephrine and vasopressin increase aortic and carotid arterial pressure when administered during cardiopulmonary resuscitation. However, we recently demonstrated that epinephrine reduces cerebral cortical microcirculatory blood flow. Accordingly, we compared the effects of nonadrenergic vasopressin with those of... |
8,358 | Management of atrial fibrillation in patients with heart failure. | Atrial fibrillation (AF) and chronic heart failure (CHF) are two major and even growing cardiovascular conditions that often coexist. However, few data are available to guide treatment of AF in patients with CHF. This review summarizes current literature concerning the following topics: (i) prognostic relevance of AF i... |
8,359 | [Cardiac arrest with subsequent permanent anoxaemic brain damage in a patient with the Brugada syndrome]. | The paper presents a case of a 20-year-old student with a history of cardiac arrest due to ventricular fibrillation. The episode of cardiac arrest occurred when the patient did not complain of any health problems, and there was no visible structural heart disease. Consequently, permanent anoxaemic brain damage was obse... |
8,360 | Prospective study of interleukin-6 and the risk of malignant ventricular tachyarrhythmia in ICD-recipients--a pilot study. | We investigated the relationship between interleukin-6 (IL-6) and the risk of experiencing spontaneous ventricular tachyarrhythmia (VT/VF) in patients with an implantable cardioverter-defibrillator (ICD).</AbstractText>Cytokine levels predict outcome in patients with advanced heart failure and are elevated in patients ... |
8,361 | Number needed to treat = six: therapeutic hypothermia following cardiac arrest--an effective and cheap approach to save lives. | In 2005, the European Resuscitation Council (ERC) guidelines stated: Unconscious adult patients with spontaneous circulation after out-of-hospital ventricular fibrillation cardiac arrest should be cooled to 32 to 34 degrees C for 12 to 24 hours. Patients with cardiac arrest from a non-shockable rhythm, in-hospital pati... |
8,362 | Percutaneous mitral valvuloplasty versus surgical treatment in mitral stenosis with severe tricuspid regurgitation. | The persistence of significant tricuspid regurgitation (TR) after percutaneous mitral valvuloplasty (PMV) is known to be an independent predictor of adverse outcome in mitral stenosis (MS). However, it remains unclear whether mitral valve (MV) surgery combined with surgical correction of TR is the better treatment opti... |
8,363 | Amiodarone for atrial fibrillation following cardiac surgery: development of clinical practice guidelines at a university hospital. | Atrial fibrillation (AF) usually develops within the first 72 h following cardiac surgery, and is often self-limiting. Within 48 h of acute onset of symptoms, approximately 50% of patients spontaneously convert to normal sinus rhythm. Thus, the relative risks and benefits of therapy must be carefully considered. The et... |
8,364 | Myocardial stunning following defibrillation threshold testing. | Implantable cardioverter-defibrillators (ICDs) have a proven mortality benefit in appropriately selected people. Several retrospective studies, though, have postulated that appropriate ICD therapy may lead to fatal, pulseless electrical alternans (PEA). This case report describes an episode of transient PEA from myocar... |
8,365 | Pharmacological modulation of gap junction function with the novel compound rotigaptide: a promising new principle for prevention of arrhythmias. | Existing anti-arrhythmic therapy is hampered by lack of efficacy and unacceptable side effects. Thus, ventricular tachycardia and fibrillation remains the strongest predictor of in-hospital mortality in patients with myocardial infarction. In atrial fibrillation, rhythm control with conventional ion channel blockers pr... |
8,366 | Pharmacologic targets for atrial fibrillation. | Despite advances in treatment, atrial fibrillation (AF) remains the most common arrhythmia in humans. Antiarrhythmic drug therapy continues to be a cornerstone of AF treatment, even in light of emerging non-pharmacologic therapies. Conventional antiarrhythmic drugs target cardiac ion channels and are often associated w... |
8,367 | Cardioembolic stroke followed by isolated celiac artery thromboembolism. | A 78-year-old man with Parkinson's disease, paroxysmal atrial fibrillation, and congestive heart failure was admitted to our hospital due to global aphasia and right-sided hemiparesis. A cardioembolic stroke from a left ventricular thrombus was diagnosed; several days later, anticoagulants were started. On the seventh ... |
8,368 | Electrophysiological properties of the atrium after cardioversion of chronic atrial fibrillation: relation to the plasma brain natriuretic peptide level. | Brain natriuretic peptide (BNP) level has been shown to increase in patients with chronic atrial fibrillation (CAF) without overt heart failure (HF). Although atrial electrical remodeling associated with CAF has been described, little is known about the effects of the BNP level on the electrophysiological properties in... |
8,369 | Fatal outcome from inappropriate defibrillation. | We present a 51-year-old morbidly obese man who underwent insertion of a single-chamber implantable cardioverter defibrillator for monomorphic ventricular tachycardia occurring after myocardial infarction. After a period of satisfactory device function, a sudden change in R-wave with atrial over-sensing heralded inappr... |
8,370 | Surgical ablation of atrial fibrillation in patients with congestive heart failure. | Congestive heart failure (CHF) and atrial fibrillation (AF), both of which cause morbidity and mortality, are mutually promoting diseases. We aimed to evaluate surgical AF ablation in CHF.</AbstractText>Among 212 patients (age 69 +/- 8.8 years, 87% with persistent AF) undergoing concomitant left atrial (LA) ablation, 7... |
8,371 | [Asymptomatic recurrence of atrial tachy-arrhythmia after circumferential pulmonary vein isolation in patients with atrial fibrillation]. | To investigate the incidence, type, and predictors of asymptomatic relapse of atrial tachy-arrhythmia (ATa) after circumferential pulmonary vein isolation (CPVI) in patients with atrial fibrillation (AF).</AbstractText>Forty-eight consecutive patients with AF underwent CPVI and were followed up. Forty-eight hours Holte... |
8,372 | Automated detection of ventricular fibrillation to guide cardiopulmonary resuscitation. | Sudden death due to ventricular fibrillation (VF) is a catastrophic event, especially in out-of-hospital settings. Prompt detection of VF and preparedness to intervene with cardiopulmonary resuscitation (CPR) and especially the delivery of an electrical shock is potentially lifesaving. The reliability and accuracy of a... |
8,373 | Minimizing ventricular pacing to reduce atrial fibrillation in sinus-node disease. | Conventional dual-chamber pacing maintains atrioventricular synchrony but results in high percentages of ventricular pacing, which causes ventricular desynchronization and has been linked to an increased risk of atrial fibrillation in patients with sinus-node disease.</AbstractText>We randomly assigned 1065 patients wi... |
8,374 | Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutter. | Amiodarone is effective in maintaining sinus rhythm in atrial fibrillation but is associated with potentially serious toxic effects. Dronedarone is a new antiarrhythmic agent pharmacologically related to amiodarone but developed to reduce the risk of side effects.</AbstractText>In two identical multicenter, double-blin... |
8,375 | Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for Less Ischemia in Non ST-Elevation Acute Coronary Syndrome Thrombolysis in My... | Ranolazine, a piperazine derivative, reduces ischemia via inhibition of the late phase of the inward sodium current (late I(Na)) during cardiac repolarization, with a consequent reduction in intracellular sodium and calcium overload. Increased intracellular calcium leads to both mechanical dysfunction and electric inst... |
8,376 | Transient ventricular fibrillation. A clinical case report. | Self-terminating ventricular fibrillation (VF) was recorded in a 42-year-old woman without coronary artery or structural heart disease. Reviewing the scientific literature, we found that this type of VF had appeared in vivo in some animal models but was sparsely described in clinical practice. This most unusual case sh... |
8,377 | [Extracorporeal shock wave lithotripsy (ESWL) can be done for lithiasic patients with cardiac arrhythmias with a lithotriptor without ECG triggering system--the experience of Iaşi Urological Department]. | The recommendations for spark gap lithotripters include that the shock waves must be delivered according to the ECG, avoiding the discharge during the refractory part of the heart activity. The lithotripters we have in our department does not have from the factory an ECG correlated triggering system. Observing that ESW... |
8,378 | Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine. | The development of selective atrial antiarrhythmic agents is a current strategy for suppression of atrial fibrillation (AF).</AbstractText>Whole-cell patch clamp techniques were used to evaluate inactivation of peak sodium channel current (I(Na)) in myocytes isolated from canine atria and ventricles. The electrophysiol... |
8,379 | Regression of electrocardiographic left ventricular hypertrophy is associated with less hospitalization for heart failure in hypertensive patients. | Reduction of electrocardiographic left ventricular hypertrophy (LVH) has been associated with decreased cardiovascular death, stroke, myocardial infarction, and atrial fibrillation. However, whether reduction of electrocardiographic LVH is associated with decreased heart failure is unclear.</AbstractText>To examine the... |
8,380 | [Case of intractable ventricula fibrillation by a multicomponent dietary supplement containing ephedra and caffeine overdose]. | Multicomponent dietary supplement containing ephedra and caffeine (DSEC) was widely used for weight loss and energy enhancement. The Food and Drug Administration (FDA) banned the sale of DSEC in 2004 because of side effects such as cardiotoxity. We report a rare case of intractable ventricular fibrillation, requiring f... |
8,381 | Postoperative atrial fibrillation following coronary artery bypass graft: clinical factors associated with in-hospital death. | To identify factors associated with a higher likelihood of in-hospital death in patients submitted to coronary artery bypass graft surgery (CABG) who developed atrial fibrillation (AF) postoperatively.</AbstractText>The authors analyzed data from 397 consecutive patients submitted to CABG that developed AF postoperativ... |
8,382 | Off-pump total myocardial revascularization in patients with left ventricular dysfunction. | To assess off-pump myocardial revascularization in patients with significant left ventricular dysfunction.</AbstractText>Four hundred and five patients with an ejection fraction less than 35% underwent myocardial revascularization without extracorporeal circulation. The procedure was performed with the aid of a suction... |
8,383 | Identifying approaches to improve the accuracy of shock outcome prediction for out-of-hospital cardiac arrest. | Analysis of the electrocardiogram (ECG) can predict if a cardiac arrest patient in ventricular fibrillation is likely to have a return of spontaneous circulation if defibrillated. The accuracy of such methods determines how useful it is clinically and for retrospective analysis.</AbstractText>We wanted to identify if t... |
8,384 | Life-saving automated external defibrillation in a teenager: a case report. | Adolescent sudden death during sport participation is commonly due to cardiac causes. Survival is more likely when an automated external defibrillator (AED) is used soon after collapse.</AbstractText>We describe a case of sudden death in a 14 year old boy with two remarkable points, successful resuscitation at school u... |
8,385 | Circadian pattern of spontaneous ventricular tachyarrhythmias in patients with implantable cardioverter defibrillators. | Previous studies have reported a circadian variation of ventricular tachyarrhythmias. However, there is no detailed information of the daily distribution of ventricular tachycardia (VT) and ventricular fibrillation (VF) episodes. The purpose of this study was to evaluate the daily distribution of episodes of ventricula... |
8,386 | Variability of coronary venous anatomy in patients undergoing cardiac resynchronization therapy: a high-speed rotational venography study. | Imaging the coronary venous (CV) tree to delineate the coronary sinus and its tributaries can facilitate electrophysiological procedures, such as cardiac resynchronization therapy (CRT) and catheter ablation. Venography also allows visualization of the left atrial (LA) veins, which may be a potential conduit for ablati... |
8,387 | Sensitivity and specificity of an automated external defibrillator algorithm designed for pediatric patients. | Electrocardiographic (ECG) rhythm analysis algorithms for cardiac rhythm analysis in automated external defibrillators (AEDs) have been tested against pediatric patient rhythms (patients < or = 8 years old) using adult ECG algorithm criteria. However these adult algorithms may fail to detect non-shockable pediatric ... |
8,388 | Criteria for the electrocardiographic diagnosis of atrial flutter improve diagnostic accuracy. | We previously developed and validated diagnostic criteria for the differentiation of atrial flutter from atrial fibrillation. In this study we examine if the criteria (F waves in the frontal plane and a partially or completely regular ventricular response) can improve the diagnostic accuracy of internists.</AbstractTex... |
8,389 | beta-Blockers for the treatment of cardiac arrest from ventricular fibrillation? | More than 160,000 people suffer sudden cardiac death each year in the US. It is estimated that ventricular fibrillation (VF) is the initial rhythm in approximately 30% of these cases. Ventricular fibrillation that does not respond to the first few defibrillation attempts is associated with mortality rates of up to 97%.... |
8,390 | The myocardial infarct size-limiting and antiarrhythmic effects of acyl-CoA:cholesterol acyltransferase inhibitor VULM 1457 protect the hearts of diabetic-hypercholesterolaemic rats against ischaemia/reperfusion injury both in vitro and in vivo. | The study was designed to characterise the influence of a novel acyl-CoA:cholesterol acyltransferase inhibitor, VULM 1457, on the severity of myocardial ischaemia-reperfusion injury in a model of diabetes mellitus and hypercholesterolaemia induced by co-administration of streptozotocin and a high fat-cholesterol diet. ... |
8,391 | Significance of appropriate defibrillator shock 3 hours and 20 minutes following implantation in a patient with hypertrophic cardiomyopathy. | Implantable defibrillators have proved effective in terminating potentially life-threatening ventricular tachyarrhythmias in hypertrophic cardiomyopathy (HCM), although the timing of appropriate shocks may be exceedingly variable.</AbstractText>We report an unusual occurrence in a 48-year-old woman with nonobstructive ... |
8,392 | Evaluating the effectiveness of dispatch-assisted cardiopulmonary resuscitation instructions. | To determine the frequency of agonal breathing during cardiac arrest (CA), its impact on the ability of 9-1-1 dispatchers to identify CA, and the impact of dispatch-assisted cardiopulmonary resuscitation (CPR) instructions on bystander CPR rates.</AbstractText>A before-after observational study enrolling out-of-hospita... |
8,393 | Effect of cardiac resynchronisation therapy on occurrence of ventricular arrhythmia in patients with implantable cardioverter defibrillators undergoing upgrade to cardiac resynchronisation therapy devices. | Cardiac resynchronisation therapy (CRT) improves outcomes in selected patients with heart failure and left ventricular dysfunction. One mechanism of benefit is believed to be favourable ventricular remodelling. Whether CRT also decreases the frequency of ventricular arrhythmias and risk of sudden death is unknown.</Abs... |
8,394 | Fibrin glue in coronary artery bypass grafting operations: casting out the Devil with Beelzebub? | Fibrin sealants are frequently used in aortocoronary bypass operations. Although they are considered to be clinically safe, we performed a retrospective analysis of our data to examine the possible side effects of Tissucol fibrin sealant, namely the acute thrombosis of grafts and native coronary arteries resulting in s... |
8,395 | Mutation-specific effects of lidocaine in Brugada syndrome. | Brugada syndrome (BrS) is a hereditary cardiac disease characterized by right bundle-branch block, an elevation of the ST-segment in leads V1 through V3 on the electrocardiogram, and ventricular fibrillation that can lead to sudden cardiac death. Mutations in the cardiac sodium channel gene SCN5A, which encodes the alp... |
8,396 | Heart failure and cardiac hypertrophy. | Left ventricular failure is the final common pathway for a wide spectrum of myocardial insults, including systemic hypertension and myocardial infarction. Although left ventricular hypertrophy is an adaptive response to pressure and volume overload, this process becomes maladaptive if left untreated and pathologic card... |
8,397 | The "incidental" episode of ventricular fibrillation: a case report. | Polymorphic ventricular tachycardia and ventricular fibrillation (VF) carry important prognostic implications, especially in the post myocardial infarction period. However, artifact on the electrocardiographic tracing can mimic VF particularly on routinely recorded rhythm strips in hospitals. Such misinterpretation can... |
8,398 | Miniaturized mechanical chest compressor: a new option for cardiopulmonary resuscitation. | After cardiac arrest, uninterrupted chest compressions with restoration of myocardial blood flow facilitates restoration of spontaneous circulation. We recognized that this may best be accomplished with a mechanical device and especially so during transport. We therefore sought to develop a lightweight, portable chest ... |
8,399 | Exclusion of a patient assessment interval and extension of the CPR interval both mitigate post-resuscitation myocardial dysfunction in a swine model of cardiac arrest. | Interruptions in cardiopulmonary resuscitation (CPR), particularly as guided by automated external defibrillators, have been implicated in poor survival from cardiac arrest. Interruptions of CPR may be reduced by eliminating repetition of shocks between periods of CPR, elimination of the interval for patient assessment... |
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