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8,500
Ventricular fibrillation induced by a radiofrequency energy delivery for idiopathic right ventricular outflow tachycardia.
We report a case of a patient with idiopathic right ventricular tachycardia who underwent radiofrequency (RF) catheter ablation. Shortly after the delivery of the RF energy, a nonsustained VT cluster occurred, and eventually resulted in VF, requiring cessation of the RF delivery and a 200 J transthoracic external cardi...
8,501
Low-dose carvedilol reduces transmural heterogeneity of ventricular repolarization in congestive heart failure.
To study the effects of carvedilol on the transmural heterogeneity of ventricular repolarization in rabbits with congestive heart failure (CHF).</AbstractText>Rabbits were randomly divided into 3 groups: control, CHF and carvedilol treated CHF group. Monophasic action potential duration (MAPD) in the 3 myocardial layer...
8,502
Cardiopulmonary arrest and resuscitation in Landrace/Large White swine: a research model.
Sudden cardiac death (SCD) is a field of continuous research. In order to answer various questions regarding SCD, several animal models have been developed. The aim of the present study is to describe our experimental model of inducing cardiac arrest in Landrace/Large White pigs, and then resuscitated according to the ...
8,503
Repolarization variability in the risk stratification of MADIT II patients.
QT variability has been reported to be associated with ventricular arrhythmias and sudden cardiac death. There is limited data regarding variability in T-wave morphology and its prognostic value. In this study, we present a novel approach for the measurement of T-wave variability (TWV) reflecting changes in T-wave morp...
8,504
Delayed termination of ventricular tachycardia after cardioversion.
Both anti-tachycardia pacing and cardioversion via an implantable cardioverter defibrillator are effective therapies for ventricular tachycardia (VT). We report a case of VT where cardioversion resulted in delayed termination of tachycardia. Potential mechanisms for this observation are discussed.
8,505
Limited cardiotoxicity after extensive thoracic surgery and intraoperative hyperthermic intrathoracic chemotherapy with doxorubicin and cisplatin.
Recently, pleural mesothelioma has been treated by cytoreductive surgery and intraoperative hyperthermic intrathoracic chemotherapy with doxorubicin and cisplatin. The well-established cardiotoxicity of doxorubicin and distressing data from an animal study raised concern about its impact on cardiac function. In the pre...
8,506
Comparison of conduction delay in the right ventricular outflow tract between Brugada syndrome and right ventricular cardiomyopathy: investigation of signal average ECG in the precordial leads.
In both Brugada syndrome (BS) and arrhythmogenic right ventricular cardiomyopathy (ARVC), electrical abnormalities in the right ventricular outflow tract (RVOT) are important for arrhythmogenesis.</AbstractText>The aim of this study was to compare conduction delay in the right ventricular in BS with that in ARVC using ...
8,507
Efficacy of cardiac resynchronization therapy in very old patients: the Insync/Insync ICD Italian Registry.
To assess the effects of cardiac resynchronization therapy (CRT) in &gt; or =80-year-old patients vs. patients &lt;80 years, in terms of clinical, functional, and echocardiographic parameters after 12 month of CRT, survival, and incidence of arrhythmic events.</AbstractText>The study population consisted of 1181 CRT pa...
8,508
[Treatment of atrial fibrillation].
Atrial fibrillation is a common and in most patients recurrent arrhythmia. Atrial fibrillation can increase mortality and causes at times severe symptoms in affected patients. Timely initiation of sustained oral anticoagulation is indicated in patients with atrial fibrillation at risk for stroke to prevent thromboembol...
8,509
Electrical atrial fibrillation induction affects the characteristics of induced arrhythmia.
Several methods are being used to induce atrial fibrillation (AF) in experimental investigations, which may affect the electrophysiologic parameters of the induced arrhythmia. The aim of our study was the investigation of temporal characteristics of AF during and after electrical induction. Direct current and high-freq...
8,510
Ventricular repolarization dynamicity provides independent prognostic information toward major arrhythmic events in patients with idiopathic dilated cardiomyopathy.
The purpose of this work was to evaluate whether ventricular repolarization dynamicity predicts major arrhythmic events in patients with idiopathic dilated cardiomyopathy (DCM).</AbstractText>Arrhythmic risk stratification in patients with DCM is still an open issue. Ventricular repolarization analysis should provide r...
8,511
Burden of atrial fibrillation after cardiac resynchronization therapy.
Cardiac resynchronization therapy (CRT) may diminish atrial fibrillation (AF) burden in patients with chronic heart failure (HF). Each of 27 patients without permanent AF in whom CRT implantation was unsuccessful was paired with 2 active CRT patients-1 responder and 1 nonresponder-based on age, gender, cause of HF, and...
8,512
Comparison of rate versus rhythm control for atrial fibrillation in patients with left ventricular dysfunction (from the AFFIRM Study).
Optimal treatment for patients with atrial fibrillation (AF) and left ventricular (LV) dysfunction is not well defined. It is unclear if sinus rhythm is of greater benefit in patients with significantly reduced ejection fraction (EF) than in patients with normal or mildly depressed LV function. The Atrial Fibrillation ...
8,513
Comparison of defibrillation efficacy and survival associated with right versus left pectoral placement for implantable defibrillators.
The preferred location for an implantable cardioverter-defibrillator (ICD) generator is the left pectoral region as a result of the shock vector formed by the active can and the lead system. However, a right pectoral site is necessary when left-sided implantation is contraindicated. The Low Energy Safety Study was a pr...
8,514
Age and follow-up time affect the prognostic value of the ECG and conventional cardiovascular risk factors for stroke in adult men.
To explore whether the predictive power of mid-life ECG abnormalities and conventional cardiovascular risk factors for future stroke change over a 30-year follow-up period, and whether a repeated examination improves their predictive power.</AbstractText>Longitudinal population-based study.</AbstractText>2,322 men aged...
8,515
Sustained abdominal compression during CPR raises coronary perfusion pressures as much as vasopressor drugs.
This study investigated sustained abdominal compression as a means to improve coronary perfusion pressure (CPP) during cardiopulmonary resuscitation (CPR) and compared the resulting CPP augmentation with that achieved using vasopressor drugs.</AbstractText>During electrically induced ventricular fibrillation in anesthe...
8,516
The effect of ischemia on ventricular fibrillation as measured by fractal dimension and frequency measures.
Most animal studies of ventricular fibrillation (VF) waveform characteristics involve healthy animals with VF initiated by electric shock. However, clinical VF is usually the result of ischemia. The waveform characteristics in these two types of VF may differ. The angular velocity (AV), frequency ratio (FR) and median ...
8,517
Cardiac troponin I after external electrical cardioversion for atrial fibrillation as a marker of myocardial injury--a preliminary report.
It is uncertain whether external electrical cardioversion (CV) of atrial fibrillation (AF) can cause myocardial injury identifiable by troponin I (cTnI).</AbstractText>To examine whether external CV of AF can cause cTnI rise as measured with high-sensitivity assay, and to identify factors determining this elevation.</A...
8,518
Spontaneous defibrillation after cessation of resuscitation in out-of-hospital cardiac arrest: a case of Lazarus phenomenon.
This report describes a case of out-of-hospital cardiac arrest with spontaneous defibrillation and subsequent return of circulation after cessation of resuscitative efforts. A 47-year-old man was found in cardiac arrest and resuscitation was initiated. As no response was achieved, the efforts were withdrawn and final r...
8,519
Return of spontaneous circulation and survival at hospital discharge in patients with out-of-hospital and emergency department cardiac arrests in a tertiary care centre.
To examine clinical variables and outcomes in patients with out-of-hospital (unwitnessed) and emergency department (ED; witnessed) cardiac arrests at a tertiary care hospital in Karachi.</AbstractText>A prospective observational study was conducted to note that outcomes in patients with first attempted cardiopulmonary ...
8,520
ANP and BNP in atrial fibrillation before and after cardioversion--and their relationship to cardiac volume and function.
The role of atrial (ANP) and B-type (BNP) natriuretic peptide in atrial fibrillation (AF) is not clear. Our aim was to describe ANP and BNP in AF, and their changes following cardioversion in persistent AF. Furthermore, we wanted to assess the association between ANP and BNP and cardiac volume and function evaluated by...
8,521
Safety and predictors of complications with a new accelerated dobutamine stress echocardiography protocol.
This study sought to document the safety of a new accelerated dobutamine-atropine stress echocardiography protocol and to analyze its complications.</AbstractText>Dobutamine-atropine stress echocardiography studies were performed using an incremental dobutamine infusion protocol from 20 to 40 microg/kg/min in 3-minute ...
8,522
Assessment of intraventricular systolic asynchrony in patients with atrial fibrillation using triplane tissue Doppler imaging.
Triplane tissue Doppler imaging (TDI) makes it possible to simultaneously obtain three apical view images and to measure the dyssynchrony index (DS) for 12 segments in patients with atrial fibrillation (AF). We evaluated the feasibility of using triplane TDI to assess intraventricular asynchrony in AF.</AbstractText>In...
8,523
The effects of changes to the ERC resuscitation guidelines on no flow time and cardiopulmonary resuscitation quality: a randomised controlled study on manikins.
The European Resuscitation Council (ERC) guidelines changed in 2005. We investigated the impact of these changes on no flow time and on the quality of cardiopulmonary resuscitation (CPR).</AbstractText>Simulated cardiac arrest (CA) scenarios were managed randomly in manikins using ERC 2000 or 2005 guidelines. Pairs of ...
8,524
Nitric oxide mediates the vagal protective effect on ventricular fibrillation via effects on action potential duration restitution in the rabbit heart.
We have previously shown that direct vagus nerve stimulation (VNS) reduces the slope of action potential duration (APD) restitution while simultaneously protecting the heart against induction of ventricular fibrillation (VF) in the absence of any sympathetic activity or tone. In the current study we have examined the r...
8,525
Novel anti-arrhythmic drugs for atrial fibrillation management.
Atrial fibrillation (AF) is a highly prevalent arrhythmia and responsible for significant morbidity, mortality and health care cost. Considerable work has been performed to improve medical options but treatment success still remains suboptimal. The use of conventional anti-arrhythmic agents has been limited by potentia...
8,526
Predictors of atrial fibrillation after coronary artery bypass surgery.
Atrial fibrillation is one of the most common arrhythmias associated with not only increased morbidity after coronary artery bypass grafting but also increased healthcare costs. Many factors are associated with atrial fibrillation onset after coronary artery bypass grafting. We prospectively examined which factors coul...
8,527
Strain rate imaging for noninvasive functional quantification of the left atrium in hypertensive patients with paroxysmal atrial fibrillation.
Strain rate (SR) imaging has been applied to the detection of regional left ventricular (LV) dysfunction but not as much to the assessment of left atrial (LA) function. We aimed to assess atrial myocardial properties during atrial fibrillation (AF) by myocardial velocity, SR and strain, focusing on the effects of hyper...
8,528
Characterization of the acute cardiac electrophysiologic effects of ethanol in dogs.
Alcohol has been related to atrial fibrillation (holiday heart syndrome), but its electrophysiologic actions remain unclear.</AbstractText>We evaluated the effects of alcohol in 23 anesthetized dogs at baseline and after 2 cumulative intravenous doses of ethanol: first dose 1.5 ml/kg (plasma level 200 mg/dl); second do...
8,529
Arginine vasopressin during sinus rhythm: effects on haemodynamic variables, left anterior descending coronary artery cross sectional area and cardiac index, before and after inhibition of NO-synthase, in pigs.
We have shown previously that arginine vasopressin (AVP) given during sinus rhythm increases mean arterial blood pressure (MAP) and left anterior descending (LAD) coronary artery cross sectional area. AVP was assumed to result in vasodilatation via activation of the endothelial nitric oxide system. The purpose of the p...
8,530
PCI of the right coronary artery via or under struts of stents protruding into the aorta.
Reported are two cases in which stent protrusion from the right coronary ostium into the aorta caused considerable difficulty in interventions. Two different methods were applied to overcome this problem. In the first (elective) case a new orifice was created at the side of the protruding stent. In the second case (acu...
8,531
Catheter ablation techniques in managing arrhythmias.
Pharmacological management of arrhythmias is not curative, is sometimes difficult, and may be associated with significant morbidity.</AbstractText>This article discusses the place of catheter ablation in the treatment of arrhythmias.</AbstractText>Supraventricular and typical atrial flutter can be cured with catheter a...
8,532
Pharmacologic management of tachycardia.
Cardiac arrhythmias may present with palpitations, chest pain, shortness of breath, dizziness and syncope. Diagnosis may be complicated by an inability to document the arrhythmia particularly when symptoms are infrequent and short lived.</AbstractText>This article aims to provide an overview of the pharmacological mana...
8,533
Emergency management of acute cardiac arrhythmias.
Anything other than normal sinus rhythm can be classified as an arrhythmia. However not all arrhythmias need acute intervention.</AbstractText>This article reviews which arrhythmias need intervention in an acute setting, and the various options available for intervention.</AbstractText>The impact of an arrhythmia upon ...
8,534
The combination of B-type natriuretic peptide and C-reactive protein provides incremental prognostic value among older patients referred for cardiac catheterization.
Recent clinical studies have demonstrated the utility of B-type natriuretic peptide (BNP) and C-reactive protein (CRP) for predicting cardiovascular outcomes. The authors hypothesized that a combined biomarker score would provide incremental prognostic value among older individuals. Clinical data, biomarkers, and echoc...
8,535
Antiarrhythmic induced electrical storm in Brugada syndrome: a case report.
Brugada syndrome (BS) may be "unmasked" by several pharmacological and/or physiological agents in an otherwise normal electrocardiogram. Once diagnosed the possibility of persistent ventricular tachycardia/fibrillation exists. Although this is treated with various antiarrhythmic agents, there remains a cohort of patien...
8,536
Vulnerability to reentry in a regionally ischemic tissue: a simulation study.
Sudden cardiac death is mainly provoked by arrhythmogenic processes. During myocardial ischemia many malignant arrhythmias, such as reentry, take place and can degenerate into ventricular fibrillation. It is thus of great interest to unravel the intricate mechanisms underlying the initiation and maintenance of a reentr...
8,537
Isolated left ventricular noncompaction in a patient presenting with a subacute myocardial infarction.
Isolated left ventricular noncompaction is a rare cardiomyopathy that is often not recognised. So far, it is not well established how best to manage this abnormality. We describe a patient in whom the diagnosis of isolated left ventricular noncompaction was made after presentation with a subacute myocardial infarction....
8,538
[Emergency therapy for acute heart failure].
Acute heart failure (AHF) is defined as the rapid onset of symptoms and signs secondary to abnormal heart function which may occur with or without previous cardiac disease. Diagnosis and classification of severity are primarily based on clinical findings. The conditions leading to and reasons for acute heart failure wh...
8,539
Fatal cardiac tamponade as a result of a peripherally inserted central venous catheter: a case report and review of the literature.
We present a case of fatal cardiac tamponade that occurred in association with a peripherally inserted central catheter (PICC) inserted from the right antecubital fossa. Migration of the catheter from the right atrium within 24 h of insertion lead to the administration of a potassium-enriched sodium chloride solution i...
8,540
Use of implantable cardioverter defibrillators in Canadian and US survivors of out-of-hospital cardiac arrest.
Cardiac arrest due to ventricular arrhythmia in the absence of a reversible cause or contraindication has been a class I indication for insertion of an implantable cardioverter defibrillator since 1998. We compared and contrasted the use of implantable cardioverter defibrillator therapy in Canada and the United States ...
8,541
Cardiac beat-to-beat alternations driven by unusual spiral waves.
Alternans, a beat-to-beat temporal alternation in the sequence of heartbeats, is a known precursor of the development of cardiac fibrillation, leading to sudden cardiac death. The equally important precursor of cardiac arrhythmias is the rotating spiral wave of electro-mechanical activity, or reentry, on the heart tiss...
8,542
A simpler cardiac arrest model in rats.
Two disadvantages of electrical induction of cardiac arrest used currently are that it is a technically complicated procedure and the consequent thermal injury, which prompts us to search for a simpler method with less adverse effect to induce ventricular fibrillation (VF) in rats. Different potential (18, 24, 30, and ...
8,543
New antiarrhythmic treatment of atrial fibrillation.
Antiarrhythmic pharmaceutical development for the treatment of atrial fibrillation (AF) is moving in several directions. The efficacy of existing drugs, such as carvedilol, for rate control and, possibly, suppression of AF, is more appreciated. Efforts are being made to modify existing agents, such as amiodarone, in an...
8,544
Atrial overdrive pacing and incidence of heart failure-related adverse events in permanently paced patients.
Atrial overdrive pacing algorithms may be effective in preventing or suppressing atrial fibrillation (AF). However, the maintenance of a heart rate incessantly faster than spontaneous could induce left ventricular (LV) dysfunction and promote heart failure (HF) on the long term.</AbstractText>This post hoc analysis exa...
8,545
Atrial fibrillatory rate and risk of left atrial thrombus in atrial fibrillation.
In atrial fibrillation (AF), a relation between electrocardiogram (ECG) fibrillatory wave amplitude and thrombus formation has been sought for long with conflicting results. In contrast, the possible relation between atrial fibrillatory rate obtained from the surface ECG and left atrial thrombus formation in patients w...
8,546
Brief review: anesthetic implications of long QT syndrome in pregnancy.
To review the effects of the long QT syndrome (LQTS) in the parturient and the current anesthetic management of patients with LQTS.</AbstractText>Relevant articles were obtained from a MEDLINE search spanning the years 1980-2006 and a PubMed search spanning the years 1949-2006. Bibliographies of retrieved articles were...
8,547
Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation.<Pagination><StartPage>61</StartPage><EndPage>68</EndPage><MedlinePgn>61-8</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVES" ...
The aim of the study was to compare the efficacy and safety of pharmacological cardioversion (PC) by nibentan, a class III antiarrhythmic agent, and electrical cardioversion (EC) in patients with persisting atrial fibrillation (AFib) and atrial flutter (AFI) receiving basic antiarrhythmic therapy. Ninety-seven patients...
8,548
Tachycardia-induced heart failure.
Heart failure associated with tachyarrhythmias can very often be reversed by dealing with the underlying tachyarrhythmia. Typically characterized by left ventricular dilation and subsequent systolic dysfunction, this disorder can be caused by both atrial and ventricular arrhythmias, most commonly chronic atrial fibrill...
8,549
Does intermittent aortic cross clamping decrease the incidence of atrial fibrillation after coronary bypass surgery?
Atrial fibrillation (AF) is the most common arrhythmia after coronary artery bypass grafting (CABG). AF is a vexing problem that causes morbidity, prolongs hospital stay, and increases costs. Numerous factors have been suggested to play a role in the development of AF. The aim of this study was to evaluate the effect o...
8,550
Intravenous and oral amiodarone for the prevention of postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass surgery.
Atrial fibrillation is still a frequent complication that increases morbidity after coronary artery bypass grafting. This prospective randomized study is designed to define efficacy of postoperative amiodarone prophylaxis in preventing atrial fibrillation after off-pump coronary artery bypass grafting.</AbstractText>On...
8,551
Preshock phase singularity and the outcome of ventricular defibrillation.
Phase singularity (PS) is a topological defect that serves as a source of ventricular fibrillation (VF). Whether or not the quantity of preshock PS determines defibrillation outcome is unclear.</AbstractText>The purpose of this study was to test the hypothesis that the number of PSs at the time of shock is an important...
8,552
Eliminating right ventricular pacing may not be best for patients requiring implantable cardioverter-defibrillators.
Excessive right ventricular (RV) pacing has been associated with adverse clinical outcomes in patients receiving pacemakers or implantable cardioverter-defibrillators (ICDs). It remains uncertain how much RV pacing is clinically deleterious.</AbstractText>This retrospective analysis assessed the relationship between th...
8,553
Optimizing implantable cardioverter-defibrillator treatment of rapid ventricular tachycardia: antitachycardia pacing therapy during charging.
Previous studies in implantable cardioverter-defibrillator (ICD) patients demonstrated the efficacy and safety of antitachycardia pacing (ATP) for rapid ventricular tachycardias (VT). To prevent shock delay in case of ATP failure, a new feature (ATP during charging) was developed to deliver ATP for rapid VT while charg...
8,554
Usefulness of ventricular dyssynchrony measured using M-mode echocardiography to predict response to resynchronization therapy.
There are discordant data about the utility of septal-to-posterior wall motion delay (SPWMD) assessed using M-mode echocardiography to predict an improvement with cardiac resynchronization therapy (CRT). Baseline SPWMD was measured using M-mode in a parasternal short-axis view in a series of 67 patients undergoing CRT ...
8,555
[Estimation of defibrillation threshold using abdominally implanted cardioverter-defibrillator with an additional defibrillation pole in a dual-coil lead endocardial defibrillation system].
Safety of patients treated with an implanted cardioverter-defibrillator (ICD) depends on defibrillator threshold (DFT). In patients with frequent ICD interventions the high DFT influences battery life-time. The aim of the study was to compare DFT in abdominally placed ICD with an active and passive can and dual-coil en...
8,556
Echocardiographic features of patients with paroxysmal atrial fibrillation.
There are several risk factors for the initiation of paroxysmal atrial fibrillation (PAF) and the underlying mechanisms are multifactorial. Our study aims to explore the echocardiographic parameters that can identify in patients with PAF compared to normal subjects.</AbstractText>Eighty consecutive patients who were wi...
8,557
Self-terminating AF depends on electrical remodeling while persistent AF depends on additional structural changes in a rapid atrially paced sheep model.
The development of atrial fibrillation (AF) is associated with electrical and structural remodeling. The aim of this study was to assess the contribution of electrical and structural remodeling to the development of AF in a rapid atrially paced ovine model with and without His bundle ablation and to determine the role ...
8,558
Exercise testing for non-invasive assessment of atrial electrophysiological properties in patients with persistent atrial fibrillation.
Experimental studies suggest that the autonomic nervous system modulates atrial refractoriness and conduction velocity in atrial fibrillation (AF). These modulatory effects are, however, difficult to assess in the clinical setting. This study sought to non-invasively characterize in patients with persistent AF, the inf...
8,559
Do small (6.6 Fr.) active and passive fixation defibrillation leads perform as well as larger sized leads? A multi-centre analysis.
The 6.6 Fr. Sprint Fidelis lead family may allow multiple lead implantation procedures with reduced risk of venous obstruction.</AbstractText>Two prospective, historically controlled, multi-centre studies were conducted in Europe (80 patients) and Canada (79 patients). The purpose was to assess the ventricular lead-rel...
8,560
[Heart-rate disorders: a challenge for the radiologist].
Arrhythmia or altered heart rhythms can present with or without underlying heart disease. Most cardiopathies give rise to arrhythmias; however, arrhythmias can also be caused in previously healthy hearts by other conditions such as metabolic disorders, electrolyte imbalances, and drug use or abuse. The clinical present...
8,561
Incidence of atrial fibrillation post-cavotricuspid isthmus ablation in patients with typical atrial flutter: left-atrial size as an independent predictor of atrial fibrillation recurrence.
Atrial fibrillation and atrial flutter often coexist. The long-term occurrence of atrial fibrillation in patients presenting with atrial flutter alone is unknown. We report the long-term follow-up in patients who underwent cavotricuspid isthmus ablation for treatment of lone atrial flutter.</AbstractText>Between Januar...
8,562
Web-based virtual cardiac symposia: a new approach for worldwide professional medical education.
The Internet is an extremely powerful tool for the transmission of data and knowledge, and the question is whether this technology can be used effectively in continuing medical education. We present our experience with worldwide, web-based virtual symposia for practicing physicians.</AbstractText>The International Soci...
8,563
Characteristics, management process, and outcome of patients suffering in-hospital cardiopulmonary arrests in a teaching hospital in Hong Kong.
To examine the demographics, process indicators of adult in-hospital cardiopulmonary arrest resuscitation, and outcomes in a teaching hospital in Hong Kong.</AbstractText>Retrospective study.</AbstractText>A university-affiliated tertiary referral hospital with 997 acute adult beds in Hong Kong.</AbstractText>Those who...
8,564
[Nonlinear dynamical complexity analysis of short-term heartbeat series using joint entropy].
In this paper is reported a method using joint entropy to analyze the nonlinear dynamical complexity of short-term heart rate variability(HRV) signal. This method can effectively pick up dynamical information from the short-term heartbeat time series, reflect the dynamical complexity of heart rate variability, and so i...
8,565
A pilot study of mechanical stimulation and cardiac dysrhythmias in a porcine model of induced hypothermia.
Hypothermia is a frequent complication of cold weather exposure and/or wilderness injuries. Anecdotal reports have postulated that patients suffering from acute hypothermia are at significantly increased risk of developing lethal cardiac dysrhythmias secondary to the physical stimulation from moving and transporting pa...
8,566
The ratio of mitral deceleration time to E-wave velocity and mitral deceleration slope outperform deceleration time alone in predicting cardiovascular outcomes: the Strong Heart Study.
The deceleration time of early mitral inflow (E) is shortened by left ventricular chamber stiffening and prolonged by impaired relaxation. For any given rate of deceleration of early mitral inflow, a higher E-wave velocity (E) is associated with a longer deceleration time. It is not known whether deceleration time norm...
8,567
Late dofetilide-associated life-threatening proarrhythmia.
This report is about a 62-year old male patient with an implantable cardioverter defibrillator (ICD) for patient activated termination of atrial fibrillation who experienced dofetilide-associated ventricular tachyarrhythmias and ICD-induced ventricular fibrillation six months after the initiation of the antiarrhythmic ...
8,568
The pinwheel experiment revisited: effects of cellular electrophysiological properties on vulnerability to cardiac reentry.
In normal heart, ventricular fibrillation can be induced by a single properly timed strong electrical or mechanical stimulus. A mechanism first proposed by Winfree and coined the "pinwheel experiment" emphasizes the timing and strength of the stimulus in inducing figure-of-eight reentry. However, the effects of cellula...
8,569
Cognitive and neurophysiological outcome of cardiac arrest survivors treated with therapeutic hypothermia.
Cognitive deficits are common in survivors of cardiac arrest (CA). The aim of this study was to examine the effect of therapeutic hypothermia after CA on cognitive functioning and neurophysiological outcome.</AbstractText>A cohort of 70 consecutive adult patients resuscitated from out-of-hospital ventricular fibrillati...
8,570
Explaining racial disparities in incidence of and survival from out-of-hospital cardiac arrest.
A prospective observational study of 4,653 consecutive cases of out-of-hospital cardiac arrest (OOHCA) occurring in New York City from April 1, 2002, to March 31, 2003, was used to assess racial/ethnic differences in the incidence of OOHCA and 30-day survival after hospital discharge among OOHCA patients. The age-adjus...
8,571
Diastolic function assessment in clinical practice: the value of 2-dimensional echocardiography.
The aim of this study was to test the hypothesis that diastolic dysfunction associated with increased filling pressures is unlikely in a structurally normal heart and to assess whether 2-dimensional echocardiography can facilitate diastolic function grading in a clinical setting.</AbstractText>Consecutive patients refe...
8,572
Atrio-ventricular block during left atrial flutter ablation.
We present a case of a patient treated with catheter ablation for atrial fibrillation aiming to pulmonary veins isolation. During ablation, atrial fibrillation organized into a left atrial flutter. Electroanatomic and electrophysiologic mapping revealed the anterior left atrium area between the mitral annulus and left ...
8,573
A model of survival following pre-hospital cardiac arrest based on the Victorian Ambulance Cardiac Arrest Register.
This study describes the epidemiology of sudden cardiac arrest patients in Victoria, Australia, as captured via the Victorian Ambulance Cardiac Arrest Register (VACAR). We used the VACAR data to construct a new model of out-of-hospital cardiac arrest (OHCA), which was specified in accordance with observed trends.</Abst...
8,574
Revised resuscitation guidelines: adrenaline versus adrenaline/vasopressin in a pig model of cardiopulmonary resuscitation--a randomised, controlled trial.
Synergistic effects of adrenaline (epinephrine) and vasopressin may be beneficial during cardiopulmonary resuscitation. However, it is unknown whether either adrenaline alone or an alternating administration of adrenaline and vasopressin is better for restoring vital organ perfusion following basic life support (BLS) a...
8,575
Comparison of rectilinear biphasic waveform with biphasic truncated exponential waveform in a pediatric defibrillation model.
To compare the rectilinear biphasic waveform with a biphasic truncated exponential waveform for pediatric defibrillation.</AbstractText>Prospective, randomized study.</AbstractText>Experimental laboratory of a university-affiliated research institute.</AbstractText>Male domestic piglets (4-24 kg).</AbstractText>Eleven ...
8,576
[Prevalence of atrial fibrillation in the Spanish population aged 60 years or more. The PREV-ICTUS study].
The aims of this study were to determine the prevalence of atrial fibrillation in individuals aged 60 years or more in Spain using a random sample of the population and to identify associated factors.</AbstractText>An analysis of the PREV-ICTUS study, a randomized cross-sectional population-based study of individuals a...
8,577
Five cases of aconite poisoning: toxicokinetics of aconitines.
Aconite poisoning was examined in five patients (four males and one female) aged 49 to 78 years old. The electrocardiogram findings were as follows: ventricular tachycardia and ventricular fibrillation in case 1, premature ventricular contraction and accelerated idioventricular rhythm in case 2, AIVR in case 3, and non...
8,578
The association between pneumococcal pneumonia and acute cardiac events.
Increased cardiac stress, hypoxemia, and inflammation may contribute to acute cardiac events, such as myocardial infarction (MI), arrhythmia, and/or congestive heart failure (CHF). We sought to determine the incidence of such events in patients who were hospitalized for community-acquired pneumococcal pneumonia.</Abstr...
8,579
Technical considerations for dominant frequency analysis.
Dominant frequency (DF) analysis of atrial electrograms has been used to characterize atrial fibrillation (AF). The aim of this study was to explore technical issues that may affect the estimation of local activation rate during AF using DF analysis.</AbstractText>Epicardial atrial electrograms recorded during AF from ...
8,580
I(Ks) block by HMR 1556 lowers ventricular defibrillation threshold and reverses the repolarization shortening by isoproterenol without rate-dependence in rabbits.
The slow delayed rectifier K+ current (I(Ks)) contributes little to ventricular repolarization at rest. It is unclear whether I(Ks) plays a role during ventricular fibrillation (VF) or ventricular repolarization at rapid rates during beta-adrenergic stimulation.</AbstractText>In an in vivo rabbit model, we evaluated th...
8,581
Effects of shock polarity reversal on defibrillation threshold in an implantable cardioverter-defibrillator.
An increased defibrillation threshold (DFT) may limit the efficacy of an implantable cardioverter-defibrillator (ICD) in termination of life-threatening ventricular arrhythmias. A search for methods of decreasing DFT has been ongoing since the introduction of ICD into clinical practice.</AbstractText>To assess the effe...
8,582
Omega-3 fatty acids and sudden arrhythmic death.
Cardiovascular disease is the leading cause of death in developed countries. In Canada, in 1999, cardiovascular disease was responsible for 36% of all deaths. Ischemic heart disease accounts for the greatest percentage of these deaths (20% of all deaths), half of which are due to the acute effects of myocardial infarct...
8,583
Ventricular long-axis function is of major importance for long-term survival in patients with heart failure.
To assess the importance of ventricular systolic and diastolic long-axis (LAX) function in comparison with short-axis (SAX) function for prediction of long-term survival in patients with heart failure.</AbstractText>Prospective epidemiological study.</AbstractText>University and county hospital.</AbstractText>Patients ...
8,584
Spontaneous gasping produces carotid blood flow during untreated cardiac arrest.
Coincident with "agonal" gasping during cardiac arrest, there are prominent increases in stroke volumes even in the absence of chest compression. In the present study, we tested the hypothesis that gasps also increase carotid blood flow (CBF) during untreated cardiac arrest.</AbstractText>The tracheas of nine domestic ...
8,585
Outcomes of CPR in the presence of partial occlusion of left anterior descending coronary artery.
To develop a clinically relevant experimental model of cardiac arrest and CPR in which a partial occlusion of the left anterior descending coronary artery (LAD) is maintained during the resuscitation procedure and the initial post-resuscitation interval.</AbstractText>Ventricular fibrillation (VF) was induced by LAD oc...
8,586
Taser-induced rapid ventricular myocardial capture demonstrated by pacemaker intracardiac electrograms.
A Taser weapon is designed to incapacitate violent individuals by causing temporary neuromuscular paralysis due to current application. We report the first case of a Taser application in a person with a dual-chamber pacemaker demonstrating evidence of Taser-induced myocardial capture.</AbstractText>Device interrogation...
8,587
Hybrid epicardial and endocardial ablation of persistent or permanent atrial fibrillation: a new approach for difficult cases.
Although percutaneous epicardial catheter ablation (PECA) has been used for the management of epicardial ventricular tachycardia, the use of PECA for atrial fibrillation (AF) has not yet been reported.</AbstractText>To evaluate the efficacy and feasibility of a hybrid PECA and endocardial ablation for AF.</AbstractText...
8,588
Cerebral protection.
Ischaemic/hypoxic insults to the brain during surgery and anaesthesia can result in long-term disability or death. Advances in resuscitation science encourage progress in clinical management of these problems. However, current practice remains largely founded on extrapolation from animal studies and limited clinical in...
8,589
Do daily threshold trend fluctuations of epicardial leads correlate with pacing and sensing characteristics in paediatric patients?
To evaluate whether the magnitude of daily ventricular pacing threshold fluctuations (Deltafluctuation) in trend graphs of stored diagrams correlate with ventricular threshold and sensing changes over time.</AbstractText>A total of 56 children received AutoCapture devices (St. Jude Medical, Sylmar, CA, USA) connected t...
8,590
[Significance of permanent atrial fibrillation in idiopathic dilated cardiomyopathy].
The significance of atrial fibrillation (AF) in idiopathic dilated cardiomyopathy (IDCM) remains discussed. The purpose of the study was to evaluate the clinical significance of permanent atrial fibrillation in patients with IDCM.</AbstractText>Systematic noninvasive and invasive studies including Holter monitoring, me...
8,591
External cardioversion of atrial fibrillation in patients with implanted pacemaker or cardioverter-defibrillator systems: a randomized comparison of monophasic and biphasic shock energy application.
External cardioversion (ECV) of atrial fibrillation (AF) may damage implanted pacemaker and cardioverter-defibrillator (ICD) systems. This prospective study evaluated the safety and efficacy of ECV comparing mono- to biphasic shock waveforms in patients with implanted rhythm devices.</AbstractText>Patients with pacemak...
8,592
The potential to improve primary prevention in the future by using BNP/N-BNP as an indicator of silent 'pancardiac' target organ damage: BNP/N-BNP could become for the heart what microalbuminuria is for the kidney.
Brain natriuretic peptide (BNP) or N-terminal pro-BNP (N-BNP) now appears to be the best independent predictor of cardiovascular mortality over and above the conventional ones like blood pressure. This may be because a high BNP/N-BNP is identifying any form of asymptomatic cardiac target organ damage (TOD) [especially ...
8,593
Long-term follow-up and risk assessment of arrhythmogenic right ventricular dysplasia/cardiomyopathy: personal experience from different primary and tertiary centres.
Limited data are available on the course of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) because of the low frequency of this diagnosis. A long-term follow-up was analysed in typical ARVD/C patients from different primary and tertiary centres, and risk factors for sudden cardiac death (SCD) and en...
8,594
Long-term follow-up and quality of life after closure of ventricular septal defect in adults.
To study patients who underwent surgical closure of a congenital ventricular septal defect (VSD) and presenting at adult age.</AbstractText>A retrospective study was carried out of 28 patients (15 male) operated upon between 1980 and 2004. Patients were investigated by echocardiography, ECG and assessed for quality of ...
8,595
Clinical predictors of left atrial thrombus and spontaneous echocardiographic contrast in patients with atrial fibrillation.
We sought to determine the relationship between clinical risk factors for systemic thromboembolism in patients with atrial fibrillation and the prevalence of left atrial (LA) spontaneous echocontrast (SEC) and LA thrombus (LAT).</AbstractText>Atrial fibrillation is associated with an increased risk of systemic thromboe...
8,596
A simpler cardiac arrest model in the mouse.
Delivering alternating currency (AC) to right ventricular endocardium to induce ventricular fibrillation (VF) in mice is complicated. We tried to validate whether transoesophageal AC stimulation could induce VF and how long AC stimulation had to be sustained to prevent the spontaneous cardioversion of VF in mice.</Abst...
8,597
[Beating heart surgery for the patient of severe mitral regurgitation with a episode of ventricular fibrillation; report of a case].<Pagination><StartPage>500</StartPage><EndPage>503</EndPage><MedlinePgn>500-3</MedlinePgn></Pagination><Abstract><AbstractText>A 77-year-old female was admitted to our hospital with a diag...
A 77-year-old female was admitted to our hospital with a diagnosis of severe mitral regurgitation. Cardiopulmonary revival was done by an emergent resuscitation for the ventricular fibrillation before admission. She had mild anoxic brain damage and brain magnetic resonance imaging (MRI) revealed severe brain atrophy. C...
8,598
Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trial.
A growing population of patients with coronary artery disease experiences angina that is not amenable to revascularization and is refractory to medical therapy. Preclinical studies have indicated that human CD34+ stem cells induce neovascularization in ischemic myocardium, which enhances perfusion and function.</Abstra...
8,599
The use of atrial overdrive and ventricular rate stabilization pacing algorithms for the prevention and treatment of paroxysmal atrial fibrillation: the Pacemaker Atrial Fibrillation Suppression (PAFS) study.
The PAFS study is a randomized, multicentre investigation of the effects of third generation anti-atrial fibrillation pacemaker algorithms in patients with paroxysmal atrial fibrillation (PAF).</AbstractText>182 patients (72 +/- 9 years, 55% male) with at least three symptomatic episodes of PAF within prior 3 months re...