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9,200 | [Immune status of patients with cardiac arrhythmias: idiopathic and in primary heart disease]. | A detailed description of immune status abnormalities of adult patients with heart arrhythmia either idiopathic or in combination with primary heart disease such as chronic myocarditis and dilated cardiomyopathy (DCMP).</AbstractText>Eighty two consecutive patients aged 16-57 years admitted to the L.A. Myasnikov Instit... |
9,201 | Effects of biphasic waveforms on outcomes of cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest. | The effects of two clinically available biphasic waveforms on the success of defibrillation and postresuscitation myocardial dysfunction after prolonged ventricular fibrillation were compared with two newly designed dual-path sequential and simultaneous rectilinear biphasic waveforms. Defibrillation via sequential puls... |
9,202 | Atrial-specific drug AVE0118 is free of torsades de pointes in anesthetized dogs with chronic complete atrioventricular block. | The novel compound AVE0118 has been shown to prevent and terminate persistent atrial fibrillation. AVE0118 blocks I(Kur), I(KAch), and I(to), leading to prolongation of atrial repolarization with no change in ventricular repolarization. This finding suggests that AVE0118 may be devoid of proarrhythmic side effects. Exp... |
9,203 | Safe and effective conversion of persistent atrial fibrillation to sinus rhythm by intravenous AZD7009. | Acute drug conversion of persistent atrial fibrillation usually fails.</AbstractText>The purpose of this study was to test the proarrhythmic potential, safety, and efficacy of the novel antiarrhythmic agent AZD7009 in patients with persistent atrial fibrillation (AF) or atrial flutter (mean duration 43 days) scheduled ... |
9,204 | [The impact of elevated serum creatinine on the prognosis of acute myocardial infarction]. | To evaluate the clinical features and outcomes in patients suffering from acute myocardial infarction combined with elevated serum creatinine.</AbstractText>We enrolled 340 consecutive patients suffering from acute myocardial infarction admitted into our hospital from 2003.2.1 - 2004.8.31. The patients were divided int... |
9,205 | The effects of ropivacaine at clinically relevant doses on myocardial ischemia in pigs. | A major risk associated with bupivacaine during myocardial ischemia is ventricular fibrillation. We investigated the influence of ropivacaine on cardiac contractility and the propensity to ventricular fibrillation before and after myocardial ischemia in a placebo-controlled pig study. Anesthetized domestic pigs were ad... |
9,206 | CHOP-rituximab with pegylated liposomal doxorubicin for the treatment of elderly patients with diffuse large B-cell lymphoma. | Thirty untreated patients, median age 69 years (range 60 - 75 years), with diffuse large B-cell lymphoma (B-DLCL) were treated with a pegylated liposomal doxorubicin (PL-doxorubicin) modified CHOP-rituximab regimen. PL-doxorubicin 30 mg/m2, was given in combination with standard dosage of prednisone, vincristine, cyclo... |
9,207 | Could sustained monomorphic ventricular tachycardia in the early phase of a prime acute myocardial infarction affect patient outcome? | Sustained monomorphic ventricular tachycardia (SMVT) in the course of a prime acute myocardial infarction is not a common arrhythmia and its prognostic significance has not been specifically elucidated. The aim of the study was to estimate the prognostic implications of the occurrence of sustained monomorphic ventricul... |
9,208 | Variation in pulmonary vein size during the cardiac cycle: implications for non-electrocardiogram-gated imaging. | Understanding pulmonary vein (PV) anatomy is important for the planning and execution of PV isolation for the treatment of atrial fibrillation, screening for PV stenosis after the procedure, and investigating the pathophysiology of atrial fibrillation. We hypothesized that significant changes in PV size occur during th... |
9,209 | Risks and benefits of combining aspirin with anticoagulant therapy in patients with atrial fibrillation: an exploratory analysis of stroke prevention using an oral thrombin inhibitor in atrial fibrillation (SPORTIF) trials. | Aspirin is used in combination with anticoagulant therapy in patients with atrial fibrillation (AF), but evidence of additional efficacy is not available.</AbstractText>We compared ischemic events and bleeding in the SPORTIF III and IV randomized trials of anticoagulation with warfarin (international normalized ratio 2... |
9,210 | A prospective study of outcome of in-patient paediatric cardiopulmonary arrest. | Few prospective studies of the incidence and outcome of paediatric in-hospital cardiopulmonary arrest have been reported to enable quality assurance comparisons within and between institutions.</AbstractText>All cardiac and respiratory arrests and their management over a 41-month period in children not subject to palli... |
9,211 | Obstructive sleep apnea and plasma natriuretic peptide levels in a community-based sample. | We hypothesized that alterations in cardiac hemodynamics associated with obstructive sleep apnea-hypopnea (OSAH) would be reflected in higher natriuretic peptide levels. We examined the association of OSAH with natriuretic peptides in a community-based sample.</AbstractText>Cross-sectional, retrospective, observational... |
9,212 | Incidence of cross-border emergency care and outcomes of cardiopulmonary resuscitation in a unique European region. | Emergency medical service (EMS) systems in Europe have developed differently due to legal, educational and organisational aspects. The aim of the present study was to compare cardiopulmonary resuscitation (CPR) outcomes and characteristics in three differently organised and staffed EMS systems in close vicinity.</Abstr... |
9,213 | A case of a concealed type of Brugada syndrome with a J wave and mild ST-segment elevation in the inferolateral leads. | We report a patient with a concealed type of Brugada syndrome. The electrocardiogram in the emergency department revealed atrial fibrillation with an almost normal ST segment. Slight electrocardiogram abnormalities of the J wave and mild ST-segment elevation appeared in the inferolateral leads a few days later. Althoug... |
9,214 | Cardiovascular changes after naloxone administration in propofol-sedated piglets during opioid overdose. | Naloxone is an opioid receptor antagonist. Even when used in modest doses, it has been associated with serious cardiopulmonary side-effects. In this experimental porcine study, we examined the cardiac effects of naloxone during an opioid overdose.</AbstractText>Cardiac parameters, changes in the left ventricular compli... |
9,215 | The effect of cryoinjury on ventricular tachycardia in the swine right ventricle. | This study was performed to assess the influence of the cryoinjury on the dynamics of wavefronts and to determine whether they can convert ventricular fibrillation (VF) to ventricular tachycardia (VT) in fibrillating right ventricular (RV) of swines using an optical mapping system. A cryoinjury with a diameter of 12 mm... |
9,216 | Glibenclamide attenuates the antiarrhythmic effect of endotoxin with a mechanism not involving K(ATP) channels. | The role of K(ATP) channels in the antiarrhythmic effect of Escherichia coli endotoxin-induced nitric oxide synthase (iNOS) was examined in an anesthetised rat model of myocardial ischemia and reperfusion arrhythmia by using glibenclamide (1 mg kg(-1)), nateglinide (10 mg kg(-1)) and repaglinide (0.5 mg kg(-1)). Endoto... |
9,217 | Negative-tension instability of scroll waves and winfree turbulence in the oregonator model. | Excitable media support self-organized scroll waves which can be unstable and give rise to three-dimensional wave chaos. Winfree turbulence of scroll waves results from the negative-tension instability of scroll waves; it plays an important role in the cardiac tissue where it may lead to ventricular fibrillation. By nu... |
9,218 | Increase in rapid defibrillation programmes after publication of guidelines. | . To monitor the implementation of in-hospital resuscitation strategies including (i) rapid defibrillation programmes, (ii) the use of amiodarone for prolonged ventricular fibrillation, and (iii) uniform data collection on resuscitation, all recommended by international guidelines published in 2000 and by Finnish natio... |
9,219 | Prophylactic amiodarone for prevention of atrial fibrillation after cardiac surgery: a meta-analysis. | Amiodarone has been proposed to decrease atrial fibrillation after cardiac surgery. The literature was systematically reviewed for randomized trials comparing amiodarone with control for prevention of atrial fibrillation. Data were extracted on study characteristics, quality, and incidence of atrial fibrillation, cardi... |
9,220 | Hemodynamic support with the pulsatile catheter pump in a sheep model of acute heart failure. | This study was aimed to mimic clinical heart failure (HF) conditions and to assess the effect of pulsatile catheter (PUCA) pump support on hemodynamics and tissue perfusion in a sheep model of acute HF. In 14 sheep, HF was induced by partial occluding the middle left circumflex coronary artery combined with pacemaker-i... |
9,221 | [Angiotensin receptor blockers and cardiac rhythm disorders]. | Angiotension Receptor Blockers (ARB) are able to prevent the occurrence of atrial fibrillation (AF) through various mechanisms among them: neurhumoral antagonism and hemodynamic control. This occurs during arterial hypertension and chronic heart failure both diseases known to be associated with left atrial dysfunction.... |
9,222 | Transthoracic incremental monophasic versus biphasic defibrillation by emergency responders (TIMBER): a randomized comparison of monophasic with biphasic waveform ascending energy defibrillation for the resuscitation of out-of-hospital cardiac arrest due to ventricular fibrillation. | Although biphasic, as compared with monophasic, waveform defibrillation for cardiac arrest is increasing in use and popularity, whether it is truly a more lifesaving waveform is unproven.</AbstractText>Consecutive adults with nontraumatic out-of-hospital ventricular fibrillation cardiac arrest were randomly allocated t... |
9,223 | Mild left ventricular dysfunction is associated with thrombogenicity in cardioembolic stroke. | Transesophageal echocardiography (TEE) has been recognized as a valuable tool for identifying the left cardiac thrombus (LCT) or spontaneous echocardiographic contrast (SEC). We aimed to identify risk groups where TEE should be performed in patients with suspected cardioembolic stroke according to magnetic resonance im... |
9,224 | Multiple failed external defibrillation attempts during robot-assisted internal mammary harvest for myocardial revascularization. | We describe multiple failed external defibrillation attempts via rescue defibrillation pads for ventricular fibrillation that occurred secondary to direct electrical current transmission through the pericardial sac from electrocautery during robot-assisted internal mammary harvest. Only after resumption of two-lung ven... |
9,225 | Ventricular fibrillation induced by ischemia-reperfusion is not prevented by the NPY Y2 receptor antagonist BIIE0246. | Neuropeptide Y is released together with norepinephrine from sympathetic nerve terminals during conditions of increased sympathetic activity. Neuropeptide Y is known to inhibit vagal activity, and accordingly, it might increase the risk for ventricular fibrillation during myocardial ischemia-reperfusion, with concomita... |
9,226 | Prevalence of systolic impairment in an unselected regional population with hypertrophic cardiomyopathy. | Hypertrophic cardiomyopathy (HC) may transition to a phase characterized by systolic impairment resembling dilated cardiomyopathy. This study retrospectively assessed the incidence of left ventricular (LV) systolic impairment at initial clinical evaluation in 248 consecutive patients with HC (mean age 53 +/- 16 years).... |
9,227 | Torsade-de-pointes in a patient under flecainide treatment, an unusual case of proarrhythmicity. | Flecainide is an antiarrhythmic considered safe in patients who have no structural cardiopathy, and frequently used in the prevention of atrial fibrillation. However, in patients with a history of infarction and/or severe conduction disorders, its proarrhythmicity may be lethal. Torsade-de-pointes type tachycardia is n... |
9,228 | The cost comparison of rhythm and rate control strategies in persistent atrial fibrillation. | Our sub study was designed to analyze the cost effectiveness of two alternative treatment strategies with a view to improved allocation of the limited therapeutic resources. To that effect we conducted detailed analysis of the related costs and other relevant data collected in the course of the HOT CAFE study.</Abstrac... |
9,229 | The cardioprotective effect of isosteviol on rats with heart ischemia-reperfusion injury. | This study was designed to assess the cardioprotective effect of isosteviol on rats with heart ischemia-reperfusion (IR) injury and to explore the mechanism of action of the compound. Sprague Dawley rats were divided into 8 groups (n=10-12): a sham-operated control and 7 ischemia-reperfusion groups (IR control, 3 isost... |
9,230 | [Polymorphic ventricular tachycardia in acute myocardial infarction without ST elevation in a patient with thrombocytopenia]. | 67-year-old woman with thrombocytopenia (treated with prednisolon and azathiopryn) was admitted because of acute myocardial infarction without ST segment elevation (NSTEMI). From the 2nd day we observed increasing QTc interval from 461 ms with normal potassium level. Suddenly on the 6th day of the so far uncomplicated ... |
9,231 | [Long QT syndrome due to olanzapine administration]. | A case of a 53 year old female with olanzapine-induced QT interval prolongation and ventricular fibrillation is described. The relationship between neuroleptic drugs and the risk of sudden cardiac death is discussed. |
9,232 | Metabolic risk factors for stroke and transient ischemic attacks in middle-aged men: a community-based study with long-term follow-up. | The impact of lipometabolic and glucometabolic disturbances on stroke incidence remains to be characterized in detail. We investigated relations of a comprehensive panel of baseline lipometabolic and glucometabolic variables to incident fatal and nonfatal stroke or transient ischemic attack (TIA), and stroke subtypes.<... |
9,233 | Electrical storm in patients with an implantable defibrillator: incidence, features, and preventive therapy: insights from a randomized trial. | The purpose of this study was to assess the incidence, features, and clinical sequelae of 'electrical storm' (ES).</AbstractText>This study is a prospectively designed secondary analysis of SHIELD; a randomized trial of azimilide for suppression of ventricular tachycardia/fibrillation (VT/VF) leading to implanted cardi... |
9,234 | Treatment practices in heart failure with preserved left ventricular ejection fraction: a prospective observational study. | Current guidelines for treatment of patients with heart failure (HF) and preserved left ventricular ejection fraction (LVEF) are empirical. One of the objectives of the ETICS study was to evaluate medical treatment at discharge and after 1 year in patients hospitalised for a first episode of HF in 2000. We report the r... |
9,235 | [Study on effect of Tiaomaiyin injection on experimental arrhythmia]. | To study the effect of Tiaomaiyin injection on the experimental arrhythmia for analyzing its underlying mechanism in the treatment of cardiovascular disease.</AbstractText>Experimental animals anesthetized with 20% urethane (6 mL x kg(-1)) were evenly randomized into control group, positive control group, low-dose and ... |
9,236 | [Advantages of restoration and maintenance of sinus rhythm in middle aged patients with atrial fibrillation and chronic heart failure]. | Patients (n=223, age 47-64 years) with persistent nonvalvular atrial fibrillation and functional class II-III chronic heart failure were treated for 2 years with aims of sinus rhythm control (n=113, strategy 1) or slowing of heart rate (n=110, strategy 2). Strategy 1 compared with strategy 2 was associated with lower t... |
9,237 | Right ventricular pacing can induce ventricular dyssynchrony in patients with atrial fibrillation after atrioventricular node ablation. | This study was designed to assess the effects of long-term right ventricular (RV) pacing on left ventricular (LV) dyssynchrony, LV function, and heart failure symptoms.</AbstractText>Atrioventricular (AV) node ablation and subsequent long-term RV pacing is a well-established treatment option in patients with atrial fib... |
9,238 | Cellular autotransplantation for ischemic and idiopathic dilated cardiomyopathy. Preliminary report. | Heart failure is highly prevalent among patients >65 years old. The incidence increases starting at approximately 45 years of age. Recent therapeutic advances have included stem cell transplantation in the affected areas of the myocardium in order to improve perfusion and myocardial performance.</AbstractText>Betwee... |
9,239 | Verification of pacemaker automatic mode switching for the detection of atrial fibrillation and atrial tachycardia with Holter recording. | Verification of the accuracy of onset, offset, and duration of automatic mode switching (AMS) of pacemakers compared with onset and end of atrial fibrillation (AF) or atrial tachycardia (AT). Correct pacemaker diagnosis of atrial tachyarrhythmias (AA) is indispensable for reliable automatic prevention and intervention ... |
9,240 | The assessment of autonomic function in chronic atrial fibrillation: description of a non-invasive technique based on circadian rhythm of atrioventricular nodal functional refractory periods. | Heart rate variability (HRV) parameters can be used to assess autonomic function and to predict outcome, but this has been done exclusively in patients with sinus rhythm. Atrial fibrillation (AF) is the commonest sustained arrhythmia and is particularly prevalent in heart failure. We have developed a simple index to as... |
9,241 | Analysis of surface electrocardiograms in atrial fibrillation: techniques, research, and clinical applications. | Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Neither the natural history of AF nor its response to therapy is sufficiently predictable by clinical and echocardiographic parameters. The purpose of this article is to describe technical aspects of novel electrocardiogram (ECG) a... |
9,242 | Left ventricular outflow tract obstruction after bioprosthetic mitral valve replacement with posterior mitral leaflet preservation. | We present a case of transient left ventricular outflow tract obstruction after mitral valve replacement with a high-profile bioprosthesis; only the posterior native mitral valve leaflet was preserved. A 76-year-old woman was admitted to our institution with pulmonary edema. Two weeks earlier, she had undergone mitral ... |
9,243 | Circulating levels of cytochrome c after resuscitation from cardiac arrest: a marker of mitochondrial injury and predictor of survival. | Ca(2+) overload and reactive oxygen species can injure mitochondria during ischemia and reperfusion. We hypothesized that mitochondrial injury occurs during cardiac resuscitation, causing release of cytochrome c to the cytosol and bloodstream while activating apoptotic pathways. Plasma cytochrome c was measured using r... |
9,244 | Characteristics and outcome amongst young adults suffering from out-of-hospital cardiac arrest in whom cardiopulmonary resuscitation is attempted. | Amongst patients suffering from out-of-hospital cardiac arrest, young adults represent a minority. However, these victims suffer from the catastrophe when they are in a very active phase of life and have a long life expectancy. This survey aims to describe young adults in Sweden who suffer from out-of-hospital cardiac ... |
9,245 | The management of atrial fibrillation in heart failure. | The development of atrial fibrillation (AF) can greatly complicate the course of heart failure (HF). Although recent trials have indicated the nonsuperiority of a rhythm control strategy in the general population with AF, this may not apply to patients with HF. We feel strongly that AF be treated aggressively in patien... |
9,246 | Atrioventricular junction ablation followed by resynchronization therapy in patients with congestive heart failure and atrial fibrillation (AVERT-AF) study design. | Atrial fibrillation (AF) and congestive heart failure (CHF) affect millions of patients in the United States. Several studies suggest that AF and in particular the irregular ventricular response might be contributing to the left ventricular dysfunction. Studies that compared pharmacologic rate control to atrioventricul... |
9,247 | Transient left ventricular dysfunction (tako-tsubo phenomenon): Findings and potential pathophysiological mechanisms. | Tako-tsubo-like left ventricular dysfunction phenomenon (TTP) is characterized by transient left ventricular apical ballooning associated with symptoms, electrocardiographic changes and minimal cardiac enzyme release in the absence of coronary artery disease. Initially described in Japan, TTP occurs worldwide, predomin... |
9,248 | Timing, setting and incidence of cardiovascular complications in patients with acute myocardial infarction submitted to primary percutaneous coronary intervention. | At the Istituto di Clinica Medica Generale e Cardiologia (Florence, Italy), the widespread use of percutaneous coronary intervention (PCI) has markedly changed the hospital course of patients with acute myocardial infarction (AMI). These patients are typically transferred to the coronary care unit (CCU) only after prim... |
9,249 | Early outcomes of out-of-hospital cardiac arrest after early defibrillation: a 24 months retrospective analysis. | Cardiovascular disease remains the most common cause of death in the United States and most other Western nations. Among these deaths, sudden, out-of-hospital cardiac arrest claims approximately 1000 lives each day in the United States alone. Most of these cardiac arrests are due to ventricular fibrillation. Though hig... |
9,250 | A rabbit Langendorff heart proarrhythmia model: predictive value for clinical identification of Torsades de Pointes. | The rabbit isolated Langendorff heart model (SCREENIT) was used to investigate the proarrhythmic potential of a range of marketed drugs or drugs intended for market. These data were used to validate the SCREENIT model against clinical outcomes.</AbstractText>Fifty-five drugs, 3 replicates and 2 controls were tested in ... |
9,251 | Ru360, a specific mitochondrial calcium uptake inhibitor, improves cardiac post-ischaemic functional recovery in rats in vivo. | The mitochondrial permeability transition pore (mPTP), an energy-dissipating channel activated by calcium, contributes to reperfusion damage by depolarizing the mitochondrial inner membrane potential. As mitochondrial Ca(2+) overload is a main inductor of mPTP opening, we examined the effect of Ru(360), a selective inh... |
9,252 | Mitochondria, the calcium uniporter, and reperfusion-induced ventricular fibrillation. | The role of the mitochondria, and in particular the calcium (Ca) uniporter, in mediating reperfusion-induced arrhythmias is a novel investigative area. This commentary assesses the importance of a new article on this topic, published in this issue of the journal. Ventricular arrhythmogenesis remains an important area o... |
9,253 | Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure. | Atrial fibrosis is an important substrate in atrial fibrillation (AF), particularly in the setting of structural heart disease. In a canine model, congestive heart failure (CHF) produces significant atrial fibrosis and the substrate for sustained AF. This atrial remodeling is a potential therapeutic target. The objecti... |
9,254 | Results from the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) trial on atrial flutter, a multicentric prospective randomized study comparing amiodarone and radiofrequency ablation after the first episode of symptomatic atrial flutter. | There is no published randomized study comparing amiodarone therapy and radiofrequency catheter ablation (RFA) after only 1 episode of symptomatic atrial flutter (AFL). The aim of the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) Trial of Atrial Flutter was 2-fold: (1) to prospectively compare first... |
9,255 | Prevalence and prognostic significance of atrial fibrillation in outpatients with heart failure due to left ventricular systolic dysfunction. | Atrial fibrillation (AF) is common in patients with heart failure (HF) due to left ventricular systolic dysfunction (LVSD), with conflicting prognostic data. The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and the developmen... |
9,256 | Atrial fibrillation is associated with increased neurohumoral activation and reduced exercise tolerance in patients with non-ischemic dilated cardiomyopathy. | To assess atrial fibrillation (AF) associated differences in proinflammatory cytokines, natriuretic peptide levels and exercise capacity in patients with heart failure (HF) secondary to non-ischemic dilated cardiomyopathy (NIDC).</AbstractText>We studied 147 NIDC patients, mean age 58.3+/-12.5 years, left ventricular (... |
9,257 | Electrocardiographic changes by accidental hypothermia in an urban and a tropical region. | Hypothermia is defined as a condition in which core temperature (rectal, esophageal, or tympanic) reaches values below 35 degrees C. This may be accidental, metabolic, or therapeutic. The accidental form is frequent in cold-climate countries and rare in those with tropical or subtropical climate. The aim of this study ... |
9,258 | Cardiac function, inflammatory mediators and mortality in critical limb ischemia. | Patients with critical limb ischemia (CLI) have a high frequency of concomitant coronary heart disease and congestive heart failure. The aim of the study was to evaluate cardiac function in relation to inflammatory markers and 1-year mortality rate among patients with CLI. The authors investigated 232 consecutive patie... |
9,259 | [Public access defibrillation. Limited use by trained first responders and laymen]. | As ventricular fibrillation is the most frequent initial heart rhythm causing out-of-hospital sudden cardiac arrest, defibrillation is of essential significance. Automated external defibrillators (AEDs) have been available for some years and as a result defibrillation can be carried out by individuals other than physic... |
9,260 | [Time-frequency analysis of ventricular fibrillation. An experimental study]. | The analysis of frequency variability during ventricular fibrillation has yielded inconsistent results. We used an experimental model of ventricular fibrillation, with a short timescale, to analyze variations in frequency and their associated spatial distribution.</AbstractText>Epicardial recordings of ventricular fibr... |
9,261 | Protective effect of simvastatin and VULM 1457 in ischaemic-reperfused myocardium of the diabetic-hypercholesterolemic rats. | This study examined the effects of simvastatin (10 mg/ kg) and VULM 1457 (50 mg/kg), an ACAT inhibitor, in the heart model of 6 min ischemia followed by 10 min reperfusion injury in the diabetic-hypercholesterolaemic (DM-HCH) rats. In the DM-HCH rats, the incidence of ventricular tachycardia (VT) had a tendency to be i... |
9,262 | Experimental evidence of improved transthoracic defibrillation with electroporation-enhancing pulses. | There is considerable work on defibrillation wave form optimization. This paper determines the impedance changes during defibrillation, then uses that information to derive the optimum defibrillation wave form.</AbstractText>Twelve guinea pigs and six swine were used to measure the current wave form for square voltage ... |
9,263 | In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival. | Review.</AbstractText>Medical literature on in-hospital cardiac arrest (IHCA) was reviewed to summarise: (a) the incidence of and survival after IHCA, (b) major prognostic factors, (c) possible interventions to improve survival.</AbstractText>The incidence of IHCA is rarely reported in the literature. Values range betw... |
9,264 | Low osmolarity transforms ventricular fibrillation from complex to highly organized, with a dominant high-frequency source. | An osmotic challenge activates volume-regulated chloride currents (I(Cl,vol)), resulting in depolarization of the resting membrane potential and shortening of action potential duration (APD). I(Cl,vol) is activated in ischemia/reperfusion, but the effects of osmotic challenges and I(Cl,vol) on ventricular fibrillation ... |
9,265 | Renal dialysis as a risk factor for appropriate therapies and mortality in implantable cardioverter-defibrillator recipients. | Patients with end-stage renal disease are at increased risk for sudden cardiac death, although the utility of implantable cardioverter-defibrillators (ICDs) in these patients is unknown.</AbstractText>The purpose of this study was to evaluate whether end-stage renal disease is an independent risk factor for appropriate... |
9,266 | Quantitative assessment of ST segment elevation in Brugada patients. | ST segment elevation in the right precordial leads constitutes the electrocardiogram (ECG) hallmark of Brugada syndrome (BS). This pattern is variable and can be concealed, but the magnitude and the cause of ST segment fluctuations have been poorly investigated.</AbstractText>Our goal was to quantify ST changes and to ... |
9,267 | Reduction of atrial tachyarrhythmia episodes during the overdrive pacing period using the post-mode switch overdrive pacing (PMOP) algorithm. | Early recurrences within 10 minutes after termination of an atrial tachyarrhythmia, such as atrial tachycardia (AT), atrial flutter, or atrial fibrillation (AF) episodes, account for a large part of paroxysmal AT/AF episodes. It is unclear whether these arrhythmias can be suppressed by overdrive pacing.</AbstractText>W... |
9,268 | [The role of permanent pacing in atrial fibrillation]. | Nowadays permanent pacing of the heart helps patients not only with pathological bradycardia or asystole in the tract of the AV blocks (AVB) and sick sinus syndrome (SSS), but is also valuable in the prevention of atrial fibrillation (AF) as well as the stabilization of the rhythm in chronic AF. For this reason patient... |
9,269 | [Cardiac stimulations for the treatment of supraventricular arrhythmias]. | Permanent cardiac stimulation in patients with supraventricular tachycardia is used primary for treatment and prevention of atrial fibrillation (AF). Different strategies of stimulation have been design for this purpose. Among the most important are: preferential standard atrial pacing, multisite atrial pacing or septa... |
9,270 | [Dual chamber pacemakers: common problems and how to treat them]. | In the last ten years the technology in Electrophysiology and Cardiac Parcing has advanced rapidly until the arrive of the implantable cardioverter defibrillator for the prevention of Sudden Death and also to the three chamber pacing for ventricular resinchronization as a treatment for advanced heart failure. In the mi... |
9,271 | [Atrial fibrillation: rhythm vs. rate control]. | The atrial fibrillation treatment has been controversial since almost a century. Several studies have been done and there is not a clear therapeutic strategy despite the new technological advances. The disyuntive persist between sinus rhythm control vs. ventricular rate control. The main studies like AFFIRM, RACE, PIAF... |
9,272 | Optical imaging of arrhythmias in tissue culture. | Cardiac cell cultures are becoming an important experimental system of minimal complexity that captures many of the salient features of myocardial tissue function and are simple enough that tissue parameters can be controlled systematically. Fundamental mechanisms that underlie normal and pathological electrophysiology... |
9,273 | Electrophysiology of the electrocardiographic changes of atrial fibrillation. | The history of atrial fibrillation is described in terms of its electrocardiographic delineation, characteristics and clinical associations. The variant configurations are described and their relationship to rhythm duration and cardioversion success. The inter-relationship of fibrillation with flutter and their diagnos... |
9,274 | Interdependence of virtual electrode polarization and conduction velocity during premature stimulation. | Fiber orientation in the heart plays a crucial role in the anisotropic nature of impulse propagation and the formation of virtual electrode polarization (VEP). The relationship between anisotropic conduction velocity and VEP is not fully understood.</AbstractText>We recorded transmembrane potential from the surface of ... |
9,275 | Adenosine A2A receptors are expressed in human atrial myocytes and modulate spontaneous sarcoplasmic reticulum calcium release. | Alterations in the cyclic AMP-dependent regulation of the cardiac ryanodine receptor (RyR2) have been proposed to account for increased spontaneous calcium release from the sarcoplasmic reticulum (SR) in patients with heart failure, ventricular tachyarrhythmias and atrial fibrillation. While the adenosine A(2A) recepto... |
9,276 | Initiation of re-entry in an excitable medium: structural investigation of cardiac tissue using a genetic algorithm. | The detailed mechanisms by which re-entry and ventricular fibrillation are initiated in the heart remain poorly understood because they are difficult to investigate experimentally. We have used a simplified excitable media computational model of action potential propagation to systematically study how re-entry can be p... |
9,277 | Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart disease. | Findings of an association between phobic anxiety and elevated risks of sudden cardiac death suggest that phobic anxiety may be related to increased risk of ventricular arrhythmias. The purpose of this study was to examine whether phobic anxiety is associated with ventricular arrhythmias in patients with documented cor... |
9,278 | Are the American College of Cardiology/Emergency Cardiac Care (ACC/ECC) guidelines useful in triaging patients to telemetry units? | To determine if the ACC/ECC guidelines (1991) properly stratify patients according to risk of arrhythmia, defined as a single event on cardiac monitoring, and benefit, defined as a subsequent management change from a recorded telemetry event.</AbstractText>In 2003, a prospective study of 217 consecutive patients admitt... |
9,279 | Interference detection in implantable defibrillators induced by therapeutic radiation therapy. | Electromagnetic fields and ionising radiation during radiotherapy can influence the functioning of ICDs. Guidelines for radiotherapy treatment were published in 1994, but only based on experience with pacemakers. Data on the influence of radiotherapy on ICDs is limited.</AbstractText>We determined the risk to ICDs of i... |
9,280 | [Genetic background of common arrhythmias]. | Progress in the field of clinical and experimental electrophysiology helps us to elucidate connections between clinical problems and genetic cellular abnormalities. So far four genes have been discovered to be responsible for inherited forms of atrial fibrillation. Several polymorphisms in genes encoding angiotensinoge... |
9,281 | The virtual ventricular wall: a tool for exploring cardiac propagation and arrhythmogenesis. | Methods for the experimental and clinical investigation of cardiac arrhythmias are limited to inferring propagation within the myocardium, from surface measurements, or from electrodes at a few sites within the cardiac wall. Biophysically and anatomically detailed computational models of cardiac tissues offer a powerfu... |
9,282 | Ventricular fibrillation as the first manifestation of primary hyperaldosteronism. | 50 years old female patient, with history of diabetes mellitus and hypertension, receiving metformin (500 mg BID) and atenolol (50 mg BID), presented to the Emergency Room with asthenia and dizziness. The patient was also receiving alternative medication (Dragon Blanco) which contains no licorice. During the emergency ... |
9,283 | Effect of endurance exercise training on heart rate onset and heart rate recovery responses to submaximal exercise in animals susceptible to ventricular fibrillation. | Both a large heart rate (HR) increase at exercise onset and a slow heart rate (HR) recovery following the termination of exercise have been linked to an increased risk for ventricular fibrillation (VF) in patients with coronary artery disease. Endurance exercise training can alter cardiac autonomic regulation. Therefor... |
9,284 | The use of unipolar intracardiac impedance for discrimination of haemodynamically stable and unstable arrhythmias in man. | To determine the feasibility of discriminating haemodynamically stable from unstable arrhythmias using right ventricular (RV) unipolar intracardiac impedance (Z).</AbstractText>A quadrapolar temporary pacing electrode was positioned at the RV apex and unipolar impedance was measured between the tip electrode and a surf... |
9,285 | [Prevalence of dangerous arrhythmia during pharmacological stress echocardiography]. | Pharmacological stress echocardiography (SE) has become a routine diagnostic and prognostic method in patients with ischemic heart disease. However, all stress tests can provoke undesirable adverse effects including dangerous arrhythmia. The aim of the study was to access the prevalence and types of arrhythmia that can... |
9,286 | Evidence of mechanoelectric feedback in the atria of patients with atrioventricular nodal reentrant tachycardia. | Patients with atrioventricular nodal reentrant tachycardia (AVNRT) could serve as a clinical model to study the effects of mechanical stretch in the electrical properties of atrial myocardium.</AbstractText>We studied 14 patients with AVNRT. Peak, mean and minimal atrial pressures, atrial refractoriness (ERP) in the ri... |
9,287 | Incidence, clinical characteristics and outcome of congestive heart failure as the initial presentation in patients with primary hyperthyroidism. | There are limited systematic data on the incidence, clinical characteristics and outcomes of congestive heart failure (CHF) in patients with hyperthyroidism. The aim of this study was to investigate the incidence, clinical characteristics and outcome of CHF as the initial presentation in patients with primary hyperthyr... |
9,288 | EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population. | The objective of the EuroHeart Failure Survey II (EHFS II) was to assess patient characteristics, aetiology, treatment, and outcome of acute heart failure (AHF) in Europe in relation to the guidelines on the diagnosis and treatment of AHF published by the European Society of Cardiology.</AbstractText>Patients hospitali... |
9,289 | Outcome of cardiopulmonary resuscitation in the intensive care units of a university hospital. | The purpose of this study is to evaluate the demographic characteristics of patients who suffered cardiac arrest in our ICUs and to identify those factors influencing outcome after resuscitation following cardiac arrest. We reviewed the records of all patients who underwent CPR in the two ICUs at the Georg-August Unive... |
9,290 | Feasibility of basic emergency medical technicians to perform selected advanced life support interventions. | Emergency medical technician-basic (EMT-B) providers often provide the initial care to victims of out-of-hospital cardiac arrest. While automated external defibrillators enable EMT-B providers to deliver rescue shocks, patients in cardiac arrest may require additional interventions that EMT-B providers may not presentl... |
9,291 | Prognostic implications of preoperative atrial fibrillation in patients undergoing aortic valve replacement: is there an argument for concomitant arrhythmia surgery? | The prognostic significance of preoperative atrial fibrillation (AF) at the time of aortic valve replacement is unknown, as is the potential role for concomitant arrhythmia surgery.</AbstractText>We performed a cohort comparison of patients with preoperative AF (n = 129) and preoperative sinus rhythm (SR, n = 252) unde... |
9,292 | Prognostic significance of left atrial size in patients with hypertrophic cardiomyopathy (from the Italian Registry for Hypertrophic Cardiomyopathy). | This study assessed left atrial (LA) dimension as a potential predictor of outcome in hypertrophic cardiomyopathy (HC). From the Italian Registry for Hypertrophic Cardiomyopathy, 1,491 patients (mean age 47 +/- 17 years; 61% men; 19% obstructive), followed for 9.4 +/- 7.4 years after the initial echocardiographic evalu... |
9,293 | Distribution and prognostic significance of QT intervals in the lowest half centile in 12,012 apparently healthy persons. | The presence of an abnormally short QT interval has been noted among survivors of idiopathic ventricular fibrillation and among close relatives of victims of unexplained sudden death. Most reported cases have had rate-corrected QT (QTc) intervals of <300 ms. The prevalence of such values in the community has not bee... |
9,294 | A comparative analysis of short- and long-term outcomes after ventricular fibrillation out-of-hospital cardiac arrest in patients with ischemic and nonischemic heart disease. | Although ventricular fibrillation (VF) out-of-hospital cardiac arrest (OHCA) occurs primarily in the setting of severe ischemic heart disease (IHD), a significant proportion of events occurs in patients who do not have severe IHD. The relative effect of IHD on survival after VF OHCA is unknown. All residents of Rochest... |
9,295 | ST-segment abnormalities and premature complexes are predictors of new-onset atrial fibrillation: the Niigata preventive medicine study. | Left ventricular hypertrophy is a known risk factor for atrial fibrillation (AF). However, it is not well understood whether other electrocardiogram abnormalities are associated with development of AF.</AbstractText>This was a community-based cohort study based upon a database of annual health examinations. We included... |
9,296 | A history of heart failure predicts arrhythmia treatment efficacy: data from the Antiarrythmics versus Implantable Defibrillators (AVID) study. | In survivors of life-threatening ventricular tachycardia (VT), a history of CHF (HxCHF) before the VT episode may provide different prognostic information than their measured left ventricular ejection fraction (LVEF).</AbstractText>We evaluated outcomes from patients in the AVID study. Patients were included in the stu... |
9,297 | Quantification of the risk and predictors of hyperkalemia in patients with left ventricular dysfunction: a retrospective analysis of the Studies of Left Ventricular Dysfunction (SOLVD) trials. | Limited data are available to predict the occurrence of hyperkalemia. Risk assessment is complicated by the lack of consistency of definition between trials.</AbstractText>We conducted a retrospective analysis of the SOLVD to evaluate the incidence of hyperkalemia and the value of several baseline characteristics as pr... |
9,298 | [In-hospital resuscitation. Concept of first-responder resuscitation using semi-automated external defibrillators (AED)]. | The prognosis after in-hospital resuscitation has not significantly improved in the last 40 years. This account presents the results over a three-year period of a hospital-wide emergency plan which implements the use of an automated external defibrillator (AED) by the first responder to the emergency call.</AbstractTex... |
9,299 | Outcome of cardiopulmonary resuscitation in intensive care units in a university hospital. | The purpose of this study is to evaluate the demographic characteristics of patients who suffered cardiac arrest in our intensive care units (ICUs) as well as to identify those factors influencing outcome after resuscitation following cardiac arrest.</AbstractText>We reviewed the records of all patients who underwent c... |
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