PMID
int64 35.7M
36.4M
| Title/Abstract
stringlengths 22
8.78k
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101
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stringlengths 4
64
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|---|---|---|---|
36,284,295
|
cyclic workflow improv implement learn point morbid mortal meet morbid mortal meet mms organ hospit depart educ purpos learn advers event ae improv patient care mms often lack effect due unsuccess systemat follow area improv effect improv patient safeti care therefor new strategi focus implement area improv daili practic necessari studi aim see could improv implement meet outcom mm use cyclic workflow factor import achiev implement
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D006282;D003142
|
T054;T170;T097;T080
|
36,284,294
|
applic deep learn artifici intellig techniqu classif clinic orthodont photo take facial intraor clinic photo one essenti part orthodont diagnosi treatment plan among diagnost procedur classif shuffl clinic photo orient initi step easi machin classifi photo varieti facial dental situat articl present convolut neural network cnns deep learn techniqu classifi orthodont clinic photo accord orient
|
D001185;D000077321
|
T090;T073;T066
|
36,284,293
|
use parih assess implement surgic safeti checklist intern qualit studi strategi select implement surgic safeti checklist ssc key factor abil improv patient safeti underutil implement framework inform implement process hinder understand checklist vari effect differ context studi explor extent ssc implement practic could assess parih framework examin could support develop target recommend improv ssc implement high incom set
|
D057189;D061214
|
T058;T170
|
36,284,292
|
ca nt qualit studi explor case contact experi covid contact trace low engag contact trace covid dramat reduc impact littl known experi environ characterist case contact influenc engag
|
D016358;D000086382
|
T058;T067;T047
|
36,284,291
|
biomark beyond brca promis combinatori treatment strategi overcom resist parp inhibitor poli adp ribos polymeras parp inhibitor parpi exploit concept synthet lethal offer great promis treatment tumor defici homolog recombin hr repair parpi exert antitumor activ block poli adp ribosyl ation paryl trap parp damag dna date us food drug administr fda approv four parpi treatment sever cancer type includ ovarian breast pancreat prostat cancer although patient hr defici tumor benefit parpi major tumor ultim develop acquir resist parpi furthermor even though brca mutat common use marker parpi sensit current clinic practic patient brca mutat parpi sensit diseas thus urgent need elucid molecular mechan parpi resist support develop ration effect treatment strategi aim overcom resist parpi well reliabl biomark accur identifi patient like benefit treatment parpi either monotherapi combin agent call marker guid effect therapi mget review summar molecular mechan drive efficaci resist parpi well emerg therapeut strategi overcom parpi resist also highlight identif potenti marker predict parpi resist guid promis parpi base combin strategi
|
D009369;D010051
|
T191
|
36,284,290
|
serum apolipoprotein iv level associ flow mediat dilat patient type diabet mellitus endotheli dysfunct common diabet apolipoprotein apo iv function antagon inflamm oxid stress present studi aim investig relationship flow mediat dilat fmd serum apoa iv level type diabet mellitus tdm patient method total tdm patient chest discomfort enrol studi baselin characterist clinic paramet document endotheli function particip evalu examin fmd brachial arteri sever coronari atherosclerosi determin quantit coronari angiographi serum apoa iv level measur elisa
|
D003924;D003324
|
T047
|
36,284,289
|
effect differ depth anesthesia periop inflammatori reaction hospit outcom elder patient undergo laparoscop radic gastrectomi investig effect differ depth anesthesia inflammatori factor hospit outcom elder patient undergo laparoscop radic gastrectomi gastric cancer order select appropri depth anesthesia improv prognosi patient undergo surgeri improv qualiti life patient
|
D010535;D015742;D013274
|
T061;T121;T109;T060;T191
|
36,284,288
|
effect glycopyrrol vasopressor requir non elect cesarean section spinal anesthesia random doubl blind placebo control trial studi aim investig whether prophylact use glycopyrrol decreas vasopressor requir prevent hypotens follow spinal anesthesia non elect cesarean section
|
D000775;D007022;D006973;D014987;D000773
|
T061;T033;T047
|
36,284,287
|
preval factor associ food insecur eight high altitud citi peru second wave covid pandem retrospect cross section studi food insecur increas covid pandem affect estim million peopl howev littl evid avail pandem relat characterist influenc food secur high altitud popul object studi assess factor associ food insecur high altitud peruvian citi second epidem wave covid
|
D000086382
|
T047;T067
|
36,284,286
|
parathyroid carcinoma pregnanc novel pathogen cdc mutat case report parathyroid carcinoma uncommon caus pth depend hypercalcemia hand case report parathyroid carcinoma pregnanc
|
D010282;D006934;D000236
|
T047;T191
|
36,284,285
|
serolog evid chronic pulmonari aspergillosi tuberculosi patient kenya pulmonari tuberculosi ptb signific risk factor fungal infect cavitari lesion post ptb serv good reservoir fungal colon subsequ infect furthermor sever immunosuppress associ hiv tb co infect anoth predisposit inadequ capac investig manag fungal infect ptb patient increas morbid mortal studi aim provid serolog evid chronic pulmonari aspergillosi cpa among ptb patient kenya toward analys serum sampl patient present persist clinic featur ptb infect despit tb treatment four referr hospit
|
D014397;D014376;D055732;D009181;D009169
|
T047;T007
|
36,284,284
|
perspect mental health servic medic student ugandan medic school univers base mental health servic medic student remain challeng particular low incom countri due poor servic avail prior studi explor avail mental health servic high incom countri littl known mental health servic countri sub saharan africa uganda medic student higher risk develop mental health challeng cours studi compar student thus need well structur mental health servic group student aim studi explor perspect mental health servic medic student public univers uganda
|
D013337;D008605
|
T058;T097
|
36,284,283
|
entrust profession activ junior brazilian medic student communiti medicin entrust profession activ epa defin promot workplac particip undergradu medic student general context high incom countri focus secondari tertiari health care sector epa limit applic train health care context low middl incom countri focus primari health care instanc context communiti medicin purpos articl report process result defin epa undergradu medic train communiti health care set
|
D013337;D004504;D007396
|
T065;T097
|
36,284,282
|
preliminari studi confoc laser endomicroscopi vitro specimen endometrium studi observ describ morpholog characterist endometrium resect uterus use confoc laser endomicroscopi includ benign endometrium non atyp endometri hyperplasia atyp endometri hyperplasia endometri carcinoma therebi lay foundat find precis local resect endometri lesion given feasibl confoc laser endomicroscopi assist hysteroscopi
|
D004714;D016889;D011230
|
T047;T191
|
36,284,281
|
shift diagnost classif migrain initi prevent treatment eptinezumab post hoc analysi promis studi month headach frequenc direct correl personalsociet burden impact sever prevent treatment decis post hoc analysi identifi shift higher lower frequenc headach categori month patient migrain particip promis clinic trial receiv two eptinezumab dose
|
D008881
|
T047
|
36,284,280
|
dose effect relationship cigarett alcohol consumpt depress symptom multipl center cross section studi chines middl age elder men although associ depress symptom cigarett alcohol well document dose respons relationship rare studi studi aim evalu dose respons relationship cigarett alcohol consumpt depress symptom chines middl age elder men provid evid guid cigarett alcohol control
|
D003863;D062789
|
T184;T073;T109;T131;T048
|
36,284,279
|
comparison anther transcriptom respons cold stress reproduct stage suscept resist japonica rice varieti rice one import cereal crop world suscept cold stress cs studi carri parallel transcriptom analysi reproduct stage anther two japonica rice varieti contrast cs resist cold suscept longj lj cold resist longj lj
|
D012275
|
T168;T002
|
36,284,278
|
escal pyrethroid resist two major malaria vector anophel funestus anophel gambia sl atatam southern ghana aggrav insecticid resist malaria vector threaten effort control malaria reduc efficaci insecticid base intervent henc need close monitor studi investig intens insecticid resist two major malaria vector funestus sensu stricto ss gambia sensu lato sl collect southern ghana assess bio efficaci sever long last insecticid net llin mosquito popul
|
D000852;D007306;D008288;D057148;D011722
|
T109;T131;T204;T047;T074
|
36,284,277
|
multi omic reveal key specif mirna mrna modul under salt toler wild emmer wheat triticum dicoccoid l salt stress one destruct environment factor limit crop growth develop microrna mirna class conserv endogen small non code rnas play crucial role regul salt respons toler plant howev mirna wild emmer wheat especi key specif salt respons mirna well studi
|
D055049;D035683
|
T123;T040;T114
|
36,284,276
|
combin denois rna seq data flux balanc analysi cluster analysi singl cell sophist method proper pre process analyz increas collect singl cell rna sequenc scrna seq data increas develop contrari best practic integr data metabol network aim describ metabol phenotyp within heterogen cell popul poor investig regard critic factor presenc fals zero valu reaction essenti fundament metabol function biomass energi product investig role denois strategi mitig problem
|
D059010;D059467
|
T081;T059;T086
|
36,284,275
|
asparagin metabol base classif reveal metabol immun heterogen hepatocellular carcinoma hepatocellular carcinoma hcc major form liver cancer poor prognosi amino acid metabol found alter cancer contribut malign progress howev asparagin metabol status relev mechan hcc bare understood
|
D006528;D008113
|
T191
|
36,284,274
|
school base cognit behaviour intervent programm address anxieti year old use short classroom activ japan quasi experiment studi although sever school base cognit behaviour intervent programm develop japan prevent improv children anxieti disord substanti time requir complet remain problem
|
D012574;D001007
|
T184;T073;T092;T041;T048
|
36,284,273
|
sumstatsrehab effici algorithm gwas summari statist assess restor generat polygen risk score diseas complex trait requir high qualiti gwas summari statist file often file difficult acquir either result unshar incomplet data date bioinformat tool focus restor miss column contain identif associ data limit potenti increas number usabl gwas summari statist file
|
D055106;D020641
|
T063;T086
|
36,284,272
|
function transcriptom analys drosophila suzukii midgut reveal mate depend reproduct plastic femal insect femal undergo huge transit energi homeostasi mate compens nutrient invest reproduct manag shift metabol mate femal experi extens morpholog behavior physiolog chang includ increas food intak alter digest process howev mechan digest system respond mate femal remain bare character perform transcriptom analysi main digest organ midgut investig gene express vari femal mate status drosophila suzukii destruct invas soft fruit pest
|
D004330;D059467
|
T081;T204;T086
|
36,284,271
|
tumour inhibitori activ pancreat cancer bispecif nanobodi target pd l cxcr antibodi deriv drug target immun checkpoint approv treatment sever malign fewer respons patient pancreat cancer design nanobodi molecul bi target pd l cxcr target overexpress mani cancer cell play import role tumorigenesi character biochem anti tumour activ bispecif nanobodi vitro vivo
|
D061905;D010190;D018033
|
T121;T129;T191;T116
|
36,284,270
|
establish evalu predict model acut gastrointestin injuri patient prolong disord conscious establish predict model acut gastrointestin injuri agi patient prolong disord conscious pdoc evalu appli predict model method clinic data patient pdoc admit hyperbar oxygen depart januari decemb retrospect review patient divid agi group n n agi group n accord whether agi occur predict model built fit multipl independ influenc factor logist regress receiv oper characterist roc curv use evalu predict valu model hosmer lemeshow h l test use evalu good fit model roc curv calibr curv drawn evalu predict perform nomogram plot visual predict model
|
D003243;D000007
|
T037;T041
|
36,284,269
|
circul small extracellular vesicl encapsul semaa attenu myocardi ischemia reperfus injuri cardiac surgeri cardiopulmonari bypass cardiomyocyt injuri common complic cardiac surgeri cardiopulmonari bypass cpb studi shown circul small extracellular vesicl sev involv patholog process cardiovascular diseas via deliv signal molecul studi aim investig relationship circul sev encapsul long noncod rnas lncrnas cardiac injuri cpb found express sev semaa serum sampl patient cpb higher pre cpb serum sampl moreov serum deriv sev semaa level negat correl creatin kinas mb ck mb level patient underw cpb oper notabl circul sev packag semaa could uptaken cardiomyocyt like cell ac increas semaa express ac cell upregul semaa protect cardiomyocyt hypoxiareoxygen injuri confirm increas cell viabil reduc cell apoptosi inhibit ferroptosi ac cell mechanist semaa regul express b cell clllymphoma bcl solut carrier famili member slca spong mir p transfect mir p mimic bcl slca knockdown could attenu protect effect semaa cardiomyocyt conclus propos semaa transport cardiomyocyt circul sev import regulatori molecul protect cardiomyocyt ischemia reperfus injuri provid target prevent treatment myocardi ischemia reperfus injuri
|
D015428;D062085;D006348;D000067128;D035683;D039961
|
T061;T123;T026;T116;T114;T046
|
36,284,268
|
smoke mediat nicotin acetylcholin receptor nachr predict outcom head neck squamous cell carcinoma human tumor diseas head neck squamous cell carcinoma hnscc associ high mortal rate worldwid nicotin acetylcholin receptor nachr transmembran receptor protein exert biolog effect follow activ nicotin aim construct prognost signatur base express nachr among smoker hnscc
|
D011978;D006258
|
T191;T116;T192
|
36,284,267
|
de novo transcriptom profil unveil regul phenylpropanoid biosynthesi unrip piper nigrum berri black pepper piper nigrum l rich bioactiv compound make imper constitu tradit medicin although unrip fruit long use differ ayurved formul mechan gene regul result product bioactiv compound black pepper much investig explor regulatori factor favour product bioactiv compound ultim help accumul medicin import content black pepper factor enhanc biosynthesi compound could potenti candid metabol engin strategi obtain high level product signific biomolecul
|
D029222
|
T168;T002
|
36,284,266
|
comparison clinic frailti scale hospit frailti risk score risk stratifi older peopl emerg care need older adult live frailti requir treatment hospit increas seen emerg depart ed one quick simpl frailti assess tool clinic frailti scale cfs embed mani ed unit kingdom uk howev carri timetrain cost burden signific miss data hospit frailti risk score hfrs autom potenti reduc cost increas data avail test predict accuraci ed aim studi assess correl abil cfs ed hfrs predict hospit relat outcom
|
D000073496;D015673;D006480;D004632
|
T061;T184;T093;T033;T047;T046;T058
|
36,284,265
|
sometim choic made choic made choic barrier weight manag client rural general practic obes intern health issu current affect new zealand adult lead physic psychosoci health complic peopl live rural communiti experi health inequ high risk becom obes aim studi explor identifi barrier effect weight manag rural waikato general practic
|
D058006;D012424
|
T098;T102;T091
|
36,284,264
|
preacr machin learn framework identifi anti crispr protein anti crispr protein potent modul inhibit crispr cas immun system huge potenti gene edit gene therapi genom edit tool extens studi shown anti crispr protein essenti modifi endogen gene promot rna guid bind cleavag dna rna substrat recent year identifi character anti crispr protein becom hot signific research topic bioinformat howev anti crispr protein fall short share similar current known tradit screen method time consum ineffici machin learn method could fill gap power predict capabl provid new perspect anti crispr protein identif
|
D000072669;D064113
|
T063;T040
|
36,284,263
|
nova promot nsclc prolifer invas activ wnt catenin signal neuro oncolog ventral antigen nova neuron specif rna bind protein regul altern splice develop nervous system recent research found nova play signific role carcinogenesi paper examin role nova non small cell lung cancer nsclc under molecular mechan
|
D002289;D008175
|
T191
|
36,284,261
|
pre vaccin rt pcr negat contact workplac set show high sar cov neutral antibodi level asymptomat sar cov infect occur rt pcr negat individu repres poor character cohort import infect control connot household communiti base studi evalu seropreval antibodi transmiss dynam group workplac base data current unavail
|
D000086382
|
T047;T067
|
36,284,254
|
practic synthesi polyamin succinamid branch polyamin antibiot resist grow threat human health exacerb lack new antibiot describ practic synthesi seri substitut polyamin succinamid branch polyamin potenti new antibiot gram posit gram negat bacteria includ mrsa pseudomona aeruginosa prepar via michael addit acrylonitril hydrogen nitril function group primari amin built upon framework natur occur polyamin thermin norspermin spermin homo heterodimer polyamin succin amid link two differ polyamin togeth via amid bond achiev introduc carboxyl acid group first polyamin coupl releas carboxyl acid free primari amin second polyamin addit posit charg amino group along polyamin chain key factor antimicrobi activ gram negat bacteria increas increas antimicrobi activ synthesis polyamin amid dimer increas total net posit charg compar monom design practic synthesi homo hetero dimer linear polyamin spermin norspermin report sever compound display signific antibacteri activ gram posit gram negat bacteria includ mrsa pseudomona aeruginosa howev charg analogu branch polyamin carri eight posit charg physiolog ph display antibiofilm activ reduct pao g ml
|
D011073;D000181
|
T131;T109
|
36,284,239
|
two dimension devic integr toward silicon line despit technic effort upgrad advanc complementari metal oxid semiconductor circuit becom unsustain face inher silicon limit new materi sought compens silicon defici two dimension materi consid promis candid due atom thin structur exot physic properti howev potenti applic method incorpor two dimension materi silicon platform remain illustr tri bridg two dimension materi silicon technolog integr devic monolith silicon silicon substrat silicon silicon function compon circuit discuss correspond requir materi synthesi devic design circuitri integr final summar role play two dimension materi silicon domin semiconductor industri suggest way forward well technolog expect becom mainstream near futur
|
D012825;D012666
|
T196;T073
|
36,284,230
|
sex differ associ among nutrit muscl mass strength periton dialysi patient mani periton dialysi pd patient malnourish lead weaken owe decreas muscl mass howev straightforward associ could differ base sex individu studi sex base associ among nutrit muscl mass strength would help choos optim intervent improv strength patient dialysi studi aim assess associ three variabl use mediat analysi retrospect studi includ preval pd patient n mediat analysi conduct investig effect appendicular lean mass alm index associ geriatr nutrit risk index gnri handgrip strength hgs number pd patient low alm index low hgs low gnri score respect proport patient low alm index lower femal male low hgs less patient without diabet diabet patient year old higher proport low alm index hgs year old low hgs signific associ mortal sex male hgs correl gnri alm index howev femal partial correl demonstr associ among gnri alm index hgs mediat analysi show male gnri associ hgs associ partial mediat alm index data reveal alm index account relationship gnri hgs signific relationship alm index hgs also direct relationship gnri hgs femal signific associ gnri alm index hgs suggest sex nutrit supplement exercis recommend primari intervent improv strength howev intervent improv muscl qualiti could consid altern maintain strength women undergo pd
|
D018737;D010530
|
T081;T040;T061
|
36,284,229
|
remain use life predict method base psr former non linear non stationari vibrat data generat rotat machin use analyz various fault condit predict remain use life rul offer great help make prognost health manag phm develop howev complex mechan work environ make vibrat data collect easili affect hard form appropri health index hi predict rul paper psr former model propos includ phase space reconstruct psr layer transform layer psr layer util embed deepen understand vibrat data featur fusion transform layer attent mechan adopt give differ assign layer hop connect use acceler converg make structur stabl effect propos method valid intellig mainten system im bear dataset analysi predict accuraci judg paramet rmse state art method lstm gru cnn also analyz dataset compar result indic propos method effect establish precis model rul predict
|
D016571;D000465
|
T170
|
36,284,227
|
preval prediabet diabet diabet awar treatment socioeconom inequ west iran aim estim preval prediabet diabet mellitus dm estim awar treatment plasma glucos control associ factor diabet well socioeconom relat inequ preval diabet prediabet data adult age year obtain baselin phase dehgolan prospect cohort studi dehpc diabet status determin fast plasma glucos fpg mgdl andor take glucos lower medic confirm medic practition prediabet consid fpg mgdl relat concentr index rci use exhibit socioeconom inequ preval prediabet dm preval prediabet dm diabet awar treatment glycem control dm respect increas age p increas bodi mass index bmi p ex smoker p famili histori diabet fhd p comorbid p independ risk factor dm age group p ex smoker p fhd p increas chanc awar current smoker p higher educ increas chanc glycem control dm dm rci prediabet rci concentr signific among less educ particip dm concentr signific among poor rci peopl signific proport dm awar treatment due integr diabet primari health care system high preval prediabet diabet affect socioeconom inequ combin low level glycem control may place greater burden health system therefor awar receiv treatment glycem control peopl diabet socioeconom status peopl becom increas import near futur
|
D011236;D003920
|
T047
|
36,284,226
|
potenti key gene pathway associ wilm tumor quest proper candid diagnost therapeut purpos design probabl import differenti express gene genet pathway wilm tumor assess express diagnost potenti rt pcr statist analysi systemat review literatur various bioinformat analysi carri gather narrow data express end result gene compar wilm tumor normal tissu sampl use rt pcr statist test report diagnost accuraci gene correl clinicopatholog featur four gene includ cdh ncam egf igf design panel combin sensit specif differenti tumor normal tissu eight pathway involv cell cell cell basal matrix junction interact found associ diseas pathogenesi suggest gene undergo evalu valid diagnost biomark research eight propos pathway recommend
|
D009396;D007680
|
T047;T191
|
36,284,225
|
model electron health record data use end end knowledg graph inform topic model rapid growth electron health record ehr dataset open promis opportun understand human diseas systemat way howev effect extract clinic knowledg ehr data hinder spars noisi inform present graph attent embed topic model gat etm end end taxonomi knowledg graph base multimod embed topic model gat etm distil latent diseas topic ehr data learn embed construct medic knowledg graph appli gat etm larg scale ehr dataset consist million patient evalu perform base topic qualiti drug imput diseas diagnosi predict gat etm demonstr superior perform altern method task moreov gat etm learn clinic meaning graph inform embed ehr code discov interpret accur patient represent patient stratif drug recommend gat etm code avail https githubcom lab mcgillgat etm
|
D057286;D019359
|
T170;T073
|
36,284,224
|
descript analysi mobil app manag covid spain develop innov app field address current pandem multipl studi focus develop new mhealth app help curb number infect applic aim acceler identif self isol peopl expos sar cov coronavirus known caus covid close contact infect individu main object paper analyz current status covid app avail main virtual store googl play store app store spain propos novel mobil applic allow interact doctor patient follow without need real time consult face face telephon research search ehealth telemedicin app relat covid perform main onlin store googl play store app store may keyword enter search engin onlin store relev app select studi use prisma methodolog design implement propos app name covinfo main weak app studi taken account order propos novel use app healthcar system search yield total app relev studi free avail android io oper system os propos app develop mobil devic android os compat android higher app enabl doctor patient interact constant monitor patient progress without need call chat face face consult real time work address design develop applic transmiss user symptom regular doctor base fact exist applic function covinfo app offer novel servic asynchron doctor patient communic well constant monitor patient condit evolut app make possibl better manag time healthcar personnel avoid overcrowd hospit aim prevent collaps healthcar system spread coronavirus
|
D063731;D000086382;D017216
|
T047;T170;T058;T067
|
36,284,223
|
contrast respons fungal versus bacteri residu accumul within soil aggreg long term fertil soil microorgan critic soil carbon c cycl primarili regul turnov soil organ c soc adjust communiti structur contribut residu consider amount resist soc nevertheless long term fertil eg combin manur chemic fertil affect spatial distribut live microbi communiti dead microbi residu within soil aggreg fraction remain larg unclear studi analyz chang microbi communiti lipid biomark microbi residu retent amino sugar biomark also calcul contribut microbi residu organ c bulk soil differ soil aggreg mm mm mm mm vs mm vs mm aggreg result indic long term fertil could drive differenti heterogen microbi residu accumul pattern signific alter contribut fungal versus bacteri deriv c organ c within soil aggreg fraction
|
D012987;D005308
|
T073;T167
|
36,284,222
|
regular irregular astigmat bullous keratopathi use fourier harmon analysi anterior segment optic coher tomographi bullous keratopathi bk known present corneal edema descemet fold caus corneal astigmat howev report quantit evalu bk astigmat separ regular irregular astigmat studi investig regular irregular astigmat anterior posterior corneal surfac fourier harmon analysi anterior segment optic coher tomographi preoper data eye bk patient receiv corneal endotheli transplant compar data eye subject without corneal diseas anterior posterior cylind power central corneal thick cct thinnest corneal thick signific greater bk fourier harmon analysi bk eye found signific larger anterior posterior regular astigmat asymmetri compon higher order irregular asymmetri compon higher order irregular account posterior irregular astigmat increas cct increas bk higher order irregular posterior cornea also posit correl worsen best correct visual acuiti subgroup analysi found signific correl cct posterior higher order irregular intraocular surgeri laser iridotomi fuch endotheli corneal dystrophi studi signific reveal characterist corneal posterior irregular astigmat bk
|
D001251;D015715;D003316
|
T047;T046
|
36,284,221
|
three compon synthesi triazolo indazol trion spiro triazolo indazol tetraon use gosio co ii studi function graphen oxid catalyst gof sio co success synthes decor graphen oxid surfac use attach hybrid silan silicanitrogen chelat co ii catalyst character fourier transform infrar ft ir powder x ray diffract xrd energi dispers x ray edx scan electron microscopi sem transmiss electron microscopi tem raman spectra brunauer emmett teller bet thermal gravimetr tga analys synthes catalyst use effect heterogen catalyst synthesi triazolo indazol trion spiro triazolo indazol tetraon deriv solvent free condit c high thermal stabil corros resist abil catalyst recycl make catalyst favor addit easi work procedur short reaction time high convers yield benefit current method
|
D012822;D012821
|
T104;T197
|
36,284,220
|
associ complement c inhibitor pegcetacoplan reduc photoreceptor degener beyond area geograph atrophi preserv photoreceptor beyond area retin pigment epithelium atrophi critic treatment goal eye geograph atrophi ga prevent vision loss thus assess associ treatment complement c inhibitor pegcetacoplan optic coher tomographi oct base photoreceptor lamina thick post hoc analysi filli trial nct retin layer oct segment use deep learn base pipelin extract along even space contour line surround area ga primari outcom measur chang baselin standard outer nuclear layer onl thick contour line month particip treat pegcetacoplan month thicker onl along contour line compar pool sham arm mean differ ci z score unit p evid eye treat pegcetacoplan everi month z score unit p addit eye treat pegcetacoplan exhibit thicker photoreceptor inner segment layer along contour line month find suggest pegcetacoplan could slow ga progress lead reduc thin photoreceptor layer beyond ga boundari futur trial earlier diseas stage ie intermedi amd aim slow photoreceptor degener warrant consider
|
D057092
|
T047
|
36,284,219
|
patchi theoret model transmiss dynam sar cov optim control short term human movement play major part transmiss control covid within countri movement necessari includ mathemat model aim assist understand transmiss dynam covid two patch basic mathemat model covid develop analyz incorpor short term human mobil model human mobil depend epidemiolog status lagrangian approach sharp threshold diseas dynam known reproduct number comput particular portray diseas threshold less uniti diseas die diseas persist reproduct number greater uniti optim control theori also appli propos model aim investig cost effect strategi find investig usag result cost object function averag cost effect ratio acer infect avert ratio iar
|
D000086402;D000086382
|
T005;T067;T047
|
36,284,217
|
energi threshold chang volcan activ mt etna itali infer volcan tremor pattern classif proven effect method flag alert volcano unrest erupt activ mt etna itali analysi appli onlin volcan tremor data support surveil activ volcano provid time inform civil protect author howev declar alert one know long volcano unrest last climact erupt activ actual begin critic aspect consid effect prolong state alert exampl longstand unrest relat christma eve erupt herald sever month almost continu strombolian activ discuss usag threshold detect condit lead paroxysm activ challeng associ defin threshold leverag dataset episod lava fountain occur abl identifi conserv set regard threshold allow earli warn impend paroxysm almost case circa first month whole year chosen threshold also prove use predict paroxysm activ end inform provid reliabl number volcanologist assess base visual inform may avail bad weather cloudi condit
|
D018707;D014202
|
T033;T131;T070;T184
|
36,284,216
|
leadership program skill train general practition high accept without improv job satisfact cluster random improvejob studi leadership becom increas import issu medicin leadership skill job satisfact patient outcom correl posit various leadership train physician psycholog well programm develop intern yet standard establish primari care improvejob leadership program develop improv job satisfact among german general practition practic personnel accept effect evalu improvejob intervent participatori interdisciplinari multimod leadership intervent target leadership workflow communic general practic use three element two leadership workshop skill train toolbox print onlin materi month implement phase support facilit cluster randomis trial wait list control evalu effect primari outcom job satisfact assess copenhagen psychosoci questionnair rang mix method approach questionnair particip interview evalu accept intervent factor influenc implement intervent content statist analys respect cluster data structur covid pandem necessit intervent adjust onlin instead site workshop onlin materi instead facilit practic visit overal practic complet studi altogeth practic leader employ physician practic assist accord intent treat analysi job satisfact decreas baselin follow signific total studi popul studi arm subgroup practic leader show non signific increas mix multilevel regress model show effect intervent job satisfact b p influenc signific greater sens communiti b p accept improvejob workshop high especi among practic leader compar assist best worst skill train vs discuss within practic team vs group discuss vs process evalu reveal covid pandem complic chang process delay implement intervent content practic routin workshop within participatori improvejob intervent rate posit multimod intervent improv job satisfact month pandem qualit data show impair implement process unforese covid pandemictri registr registr number drks
|
D058005;D000086382
|
T047;T067;T097
|
36,284,211
|
global polar alcohol solvent water import collect act factor densiti refract index hydrogen bond forc hbd quantiti repres hydroxyl group densiti alcohol solvent water hbd pure physic defin product molar concentr solvent n factor nnf reflect number n posit f factor alcohol oh group per molecul whether hydroxyl group either primari secondari tertiari taken account f n clear linear correl physic densiti refract index alcohol deriv relationship solvent depend uvvi absorpt energi e valu xe nmr shift kinet data chloro methylpropan solvolysi hbd demonstr shown e solvent paramet reflect global polar hydrogen bond network rather specif h bond acid signific correl log k rate constant solvolysi reaction chloro methylpropan hbd show physic reason approach
|
D014867;D012031
|
T081;T121;T197;T059
|
36,284,210
|
structur conform novel bodipi ugi adduct two novel bodipi ugi boron dipyrromethen adduct exhibit peculiar room temperatur c h nmr spectra sever proton locat aromat anilin type ring lost baselin observ reveal exist dynam conform process rotat around c n bond hinder variabl temperatur h c nmr spectroscop analysi confirm conclus low temperatur spectra show distinct signal four aromat proton coalesc wherea averag signal record coalesc c particular interest rather larg differ chemic shift ortho proton coalesc ppm explain base dft comput analysi inde calcul lowest energi gas phase conform bodipi ugi adduct locat one half anilin type ring shield anisotrop cone bridg phenyl ring bodipi segment contrast solid state conform establish x ray diffract analysi show near parallel arrang aromat ring probabl induc crystal pack forc
|
D011522;D001895
|
T196
|
36,284,204
|
variabl key perform indic commerci gilthead seabream hatcheri skelet abnorm one import key perform indic kpis finfish hatcheri cope problem skelet abnorm reli understand link variabl rear condit variabl abnorm incid seabream larval popul four commerci hatcheri examin presenc abnorm monitor respect appli condit inward fold gill cover pugheaded frequent abnorm present mean sd frequenc respect abnorm observ low mean rate new abnorm type ray resorpt syndrom also found record rate normal inflat swimbladd mean surviv rate classif tree analysi indic six rear variabl potenti import predictor pugheaded six variabl caudal fin abnorm variabl surviv rate complementari genet analysi reveal differenti genet divers signific genet distanc among particip hatcheri suggest role compani specif manag genet resourc kpis variabl result discuss respect potenti use control skelet abnorm commerci hatcheri well benchmark among differ hatcheri
|
D021541
|
T013
|
36,284,203
|
studi safeti accept behavior intervent autonom drive technolog explain phenomenon declin accept autom drive technolog adt predict trend accept becom import area research explor reason declin accept autom vehicl improv user accept studi mechan influenc process relationship safeti riski adt user accept examin mediat moder effect propos intervent behavior influenc relationship two first improv accept model incorpor safeti risk factor develop subsequ psycholog chang process user accept analyz base peopl respons accid inform ultim result show safeti cognit risk regard adt signific negat impact user accept next mediat model user experi introduc moder variabl design test result model found propos behavior intervent strategi effect attenu degre impact safeti riski adt accept risk base accept explan model intervent method design studi provid scientif basi practic approach develop market autom vehicl
|
D001334
|
T056
|
36,284,202
|
anxieti adult popul onset termin social distanc protocol covid month longitudin studi social distanc protocol sdps implement respons covid pandem may serious influenc peopl mental health use sampl norwegian adult recruit onlin stratifi nation repres investig evolut anxieti follow modif nation sdps across month period onset pandem reopen societi discontinu sdps mean anxieti level fluctuat throughout observ period fluctuat relat stringenc modifi sdps high initi level almost unison show substanti last decreas anxieti first lift sdps sub group develop persist anxieti state first month younger age pre exist psychiatr diagnosi use unverifi inform platform prove predict mark higher anxieti long run conclus individu high level anxieti outbreak pandem improv social distanc protocol lift contrast sizeabl subgroup develop last clinic level anxieti first month pandem vulner prolong anxieti beyond pandem period
|
D000086382
|
T047;T067
|
36,284,201
|
salt stress decreas seed yield postpon growth process canola brassica napus l chang nitrogen carbon charact salt stress major challeng plant growth yield achiev canola brassica napus l nitrogen n consid essenti nutrient involv mani physiolog process carbon c compon plant biomass n c assimil canola plant alway inhibit salt stress howev knowledg salt stress affect biomass seed yield chang n c charact limit field experi conduct investig growth process n c charact photosynthet perform biomass accumul seed yield low high soil salt ion concentr condit lssc hssc result indic hssc postpon time earli flower stage matur stage day day respect compar lssc besid hssc decreas n c accumul cn grow stage suggest salt stress break balanc c assimil n assimil stronger effect c assimil although plant n content hssc increas photosynthesi rate earli flower stage decreas leaf area index earli flower stage also reduc addit hssc decreas n transloc effici especi stem n util effici advers effect hssc togeth result reduc biomass accumul seed yield conclus high soil salt ion concentr reduc biomass accumul seed yield canola chang n c charact
|
D029688
|
T168;T002
|
36,284,200
|
engin hiv neutral antibodi capvl manufactur improv half life broad neutral antibodi bnab cap vrc except potenc hiv consid clinic use character product bnab observ sever unusu featur first antibodi appear adher pipett tip requir tip chang serial dilut accur measur potenc second product scale proteolyt cleavag discov target extend heavi chain loop attribut proteas spent medium week cultur enabl larg scale product alter site cleavag via singl amino acid chang kma result antibodi retain potenc breadth avoid proteas cleavag also ad half life extend mutat ls improv vivo persist anim model impact neutral activ observ preserv neutral bnab vrc n pgdm ls virus panel final engin antibodi capvl retain extraordinari neutral potenc parent antibodi favor pharmacokinet profil anim model negat vitro assess autoreact capvl requisit potenc develop suitabl scale allow advanc clinic candid
|
D015497;D015658
|
T005;T047
|
36,284,199
|
chromobacterium cspp biopesticid toxic larva three diabrotica speci includ strain resist bacillus thuringiensi develop new biopesticid control western corn rootworm wcr diabrotica virgifera virgifera lecont urgent due resist evolut various control method test air dri non live prepar chromobacterium speci panama cspp multipl corn rootworm speci includ bt resist suscept wcr strain northern ncr barberi smith lawrenc southern corn rootworm scr undecimpunctata howardi barber diet toxic assay result document cspp toxic three corn rootworm speci base lethal lc effect ec molt inhibit concentr mic general toxic cspp similar among wcr strain fold less toxic ncr scr strain effect concentr ec also similar among wcr scr strain fold higher ncr strain molt inhibit mic similar among corn rootworm strain except ncr diapaus strain fold higher compar strain appar cross resist cspp current avail bt protein result indic cspp formul effect kill multipl corn rootworm strain includ bt resist wcr could develop potenti new manag tool wcr control
|
D001413;D001517
|
T007;T204
|
36,284,198
|
adapt mixtur categor amc base g comput applic trace element mixtur bladder cancer risk sever new statist method develop identifi overal impact exposur mixtur health outcom weight quantil sum wqs regress assign joint mixtur effect weight indic overal associ multipl exposur quantil base g comput general version wqs without restrict direct homogen paper propos adapt mixtur categor amc base g comput approach combin g comput optim exposur categor search use f statist amc base g comput reduc varianc within categori retain varianc categori build power predictor simul studi perform associ analysi improv use categor amc compar quantil appli method assess associ mixtur trace element concentr measur toenail risk non muscl invas bladder cancer find suggest medium level gg vs low level gg toenail zinc statist signific posit associ bladder cancer risk
|
D014131;D001749
|
T123;T196;T121;T191
|
36,284,197
|
gene express base dissect inter histotyp intra histotyp intra tumor heterogen pediatr tumor intra tumor heterogen ith foster tumor evolut resist therapi relaps recent mani evid accumul occurr genet ith pediatr cancer studi aim address downstream effect genet epigenet ith tumor microenviron interact may produc within tumor mass aim investig high throughput gene express multipl sampl hepatoblastoma neuroblastoma rhabdomyosarcoma wilm tumor princip compon analysi singl sampl hallmark gene set analysi weight gene co express network analysi perform gene express data observ differ tumor cluster histotyp case addit variabl degre ith visibl investig case ith highlight studi repres challeng tumor treatment sinc demonstr differ druggabl hallmark target may heterogen present within tumor mass potenti lead therapeut failur despit heterogen could highlight common among differ histotyp investig support feasibl move clinic histotyp driven target driven sometim agnost approach least case
|
D018740;D009364
|
T032;T191
|
36,284,196
|
autophagi induc smer attenu microtubul dynam mediat neuroprotect smer origin screen small molecul act modul autophagi smer enhanc clearanc autophag substrat mutant huntingtin addit rapamycin induc autophagi thus smer establish posit regul autophagi act independ mtor pathway increas autophagosom biosynthesi attenu mutant huntingtin fragment toxic cellular fruit fli diseas model suggest therapeut potenti despit mani previous studi molecular mechan mediat smer activ direct target remain elus analyz effect smer cell found asid autophagi induct signific stabil microtubul deceler microtubul dynam moreov report smer display neurotroph neuroprotect effect cellular level induc neurit outgrowth protect excitotoxin induc axon degener final compar effect smer autophagi induc microtubul stabil drug wherea smer rapamycin induc autophagi latter stabil microtubul wherea smer epothilon b stabil microtubul epothilon b stimul autophagi thus effect smer cell general neuron particular base uniqu spectrum bioactiv distinct known microtubul stabil autophagi induc drug
|
D000066829;D018696
|
T121;T169;T043
|
36,284,195
|
explain neural activ human listen deep learn via natur languag process narrat text deep learn dl approach may also inform analysi human brain activ state art dl tool natur languag process generat pre train transform version gpt shown generat meaning neural encod function mri narrat listen linguist featur word unpredict surpris contextu import salienc deriv gpt appli text min narrat segment variabl durat defin context next word result differ set neural predictor function mri signal record healthi listen narrat gpt surpris estim word predict error artifici network signific explain neural data superior middl tempor gyri bilater anterior posterior cingul cortic left prefront cortex gpt salienc weigh import context word signific explain neural data longer segment left superior middl tempor gyri result add novel support use dl tool search neural encod function mri dl languag model like gpt may featur use data neural process subserv languag comprehens human includ next word context relat predict
|
D001931;D000077321
|
T062;T060;T066
|
36,284,194
|
new perform analysi method roll bear base evidenti reason rule consid perturb roll bear key compon transmiss rotat machineri wide use industri field therefor vital import evalu perform reliabl roll bear aim interfer problem face roll bear oper perform evalu model base evidenti reason er rule propos articl first time domain frequenc domain characterist indic bear vibrat signal taken evalu indic evalu system construct second various indic inform unifi belief structur reliabl weight indic fulli consid er rule third simul complex work environ roll bear perturb analysi method adopt determin maximum perturb error perturb coeffici perform reliabl roll bear analys perform reliabl evalu model consid perturb propos final base whole life open data set roll bear univers cincinnati valid reliabl propos model verifi perform analysi
|
D014732
|
T070
|
36,284,193
|
synthesi anti inflammatori activ amino tetrahydrobenzo b thiophen deriv nrf activ first studi investig nuclear factor erythroid deriv like nrf activ compound contain new scaffold tetrahydrobenzo b thiophen eighteen compound synthesis confirm nrf activ nqo enzymat activ mrna express nqo ho hepa cc cell compound disrupt interact kelch like ech associ protein keap nrf via interf keap kelch domain compound exhibit anti inflammatori activ escherichia coli lipopolysaccharid lps ec stimul raw cell anti inflammatori activ compound associ abil activ nrf compound revers elev level pro inflammatori cytokin il il tnf ifn inflammatori mediat pge cox nf b compound metabol stabl human rat mous liver microsom show optimum half life intrins clearanc cl int bind mode compound physicochem properti predict via silico studi
|
D051267;D016328
|
T129;T123;T116
|
36,284,177
|
synergi amyloid oxid stress develop alzheim diseas like neurodegener hippocamp cell alzheim diseas ad type dementia affect memori think behavior symptom eventu becom sever enough interfer daili task understand etiolog pathogenesi ad necessari develop strategi ad prevent andor treatment model patholog import step achiev goal amyloid peptid inject wide use approach model ad nevertheless report model construct inject combin prooxid cocktail ferrous sulfat buthionin sulfoximin bso fab best reflect natur develop diseas relationship oxid stress deposit respect role induc patholog differ anim model ad thorough investig current paper compar effect alon associ oxid stress induc fab cocktail neurodegener hippocamp cell vitro construct fab induc ad model use rat primari hippocamp cell analyz contribut compound studi main focus prooxid aspect ad pathogenesi moreov cellular bioenerget assess routin metabol test perform determin use model data clear show aggreg alon signific less toxic hippocamp cell aggreg damag neuron glial cell prolifer remov hippocampus extern prooxid agent fe inhibit intern antioxid defens bso toxic effect hippocamp cell aggreg alon moreov hippocamp cell fight induc damag effect oxid damag howev combin extern oxid damag inhibit intern antioxid defens even toxic impair cellular defens system may mimic late phase ad associ cell damag find strong indic critic role combin oxid stress develop neurodegener vitro
|
D016229;D000544
|
T047;T116;T048
|
36,284,176
|
predict valu eosinophil level reflow patient stemi follow pci retrospect cohort studi patient acut st elev myocardi infarct stemi essenti restor myocardi perfus soon possibl howev consider proport patient reflow reflow increas risk major advers cardiac event even death role blood eosinophil count predict reflow stemi patient determin particular primari percutan coronari intervent ppci present studi aim evalu predict valu eosinophil count reflow patient stemi underw ppci total stemi patient underw ppci enrol subject divid two group accord eosinophil count primari analysi without dm secondari analysi logist regress analysi use determin whether eosinophil count independ predictor reflow entir cohort subgroup receiv oper characterist roc curv explor evalu predict valu delong test use compar area curv three roc curv low eosinophil count independ predictor reflow whole cohort adjust ci p patient dm adjust ci p patient without dm hemoglobin low eosinophil count independ predictor reflow result roc curv analysi reveal low eosinophil count moder predict effici predict reflow patient dm power superior popul patient without dm data suggest decreas eosinophil count independ risk factor reflow patient stemi underw ppci especi dm patient provid guidanc clinician identifi patient higher risk develop reflow lower risk
|
D000072657;D054318;D062645
|
T033;T047;T046;T061
|
36,284,175
|
static mandibular condyl posit studi mri condylar posit indic compar mandibular condyl posit determin magnet reson imag mri mechan devic condylar posit indic cpi method assess mandibular posit asymptomat male asymptomat femal age year free temporomandibular disord maximum intercusp bimanu manipul centric relat unguid neuromuscular posit bite registr obtain bimanu oper guidanc neuromuscular posit mri scan temporomandibular joint produc data superior condylar point mandibular posit use mount plaster cast bite registr electron cpi display data condylar sphere posit result show interclass correl coeffici rang confid interv signific differ condyl posit method p p implic studi emphas condyl posit unpredict variabl exact knowledg requir radiolog imag reli cpi assess
|
D008335;D013704
|
T023;T030
|
36,284,174
|
novel techniqu overcom fluid flow influenc carbon quantum dotspap base analyt devic paper base analyt devic promis choic rapid test lab chip detect techniqu carbon quantum dot cqds hand biocompat nanomateri industri promis due fast cost effect gram scale synthesi techniqu well signific high stabl photoluminesc pl properti durabl reliabl year howev limit entrap cqds cellulos paper way pl influenc flow cqds stream analyt fluid make sensor less accur low concentr liquid analyt therefor investig polyvinyl alcoholalkalin base method systemat generat develop entrap cqds insid crystallin matrix paper way use direct probe simpl drop detect method proof concept np dope cqd cellulos paper use make fluoresc paper base analyt devic identifi trace hg around ppb design sensor test sever month studi durabl function long period potenti industri applic
|
D045663;D008628
|
T131;T196;T073
|
36,284,173
|
profil tabriz older peopl health survey top repres communiti base cross section studi popul age consequ substanti global concern growth number older peopl one import factor increas burden non communic diseas ncds societi tabriz older peopl health survey aim understand socio demograph health relat behavior health profil older adult cross section studi conduct repres sampl communiti dwell older adult tabriz popul citi northwest iran studi use probabl proportion size sampl data collect undertaken particip place resid juli januari train interview administ questionnair measur particip socio demograph health relat behavior health profil sampl particip consist women young older peopl year old almost half sampl complet illiter daili walk sampl women report sedentari lifestyl men almost particip n current smoker higher among men vs women made live alon term sleep qualiti score men women anxieti men women depress men women social support men women men signific better women also signific sex differ women men preval diabet vs hypertens vs furthermor overal hypertens common under diseas older women signific wors older men term social disabl relat well higher burden sever ncds result studi might help region health policymak identifi target improv health status among communiti hous geriatr
|
D000073296;D006973
|
T047
|
36,284,172
|
impact orthophosph polyphosph blend dissolut transform lead ii carbon orthophosph polyphosph blend common use control lead releas drink water littl known interact lead corros scale convent corros control practic assum orthophosph control lead releas form insolubl pb phosphat miner alway occur certain condit phosphat blend may increas lead releas use continu stir tank reactor compar orthophosph polyphosph blend orthophosph basi lead ii carbon dissolut transform environment relev phosphat concentr three model polyphosph tripoli trimeta hexametaphosph use hexametaphosph strongest complex agent mol pb mol polyphosph follow tripolyphosph trimetaphosph mol pb mol polyphosph respect equival orthophosph polyphosph concentr p orthophosph trimetaphosph minim impact lead releas orthophosph tripolyphosph increas dissolv lead orthophosph hexametaphosph also increas dissolv lead h stagnat orthophosph tripolyphosph orthophosph hexametaphosph increas colloid lead h increas concentr hexameta tripoli phosphat increas dissolv lead releas three polyphosph inhibit format hydroxypyromorphit reduc phosphorus content result lead solid attribut impact orthophosph polyphosph combin complex adsorpt colloid dispers polyphosph hydrolysi lead miner precipit
|
D060766
|
T167
|
36,284,171
|
physiolog molecular respons indica japonica subspeci tetraploid rice seed germin ion beam ioniz radiat reduc yield rice also caus rice toxic consumpt kind rice threaten human health moreov product applic freon caus hole earth ozon layer increas amount ioniz radiat sun affect rice select breed new radiat resist rice varieti dri seed indica japonica subspeci tetraploid rice subject differ dose ioniz radiat investig respons germin result show relat water absorpt seed vigour ga content sharpli decreas respons three differ dose ioniz radiat regul express gene relat amylas synthesi gibberellin metabol disrupt moreov degre inhibit increas increas dose notabl ionscm radiat upregul osgaox express result sharp increas ga content indica japonica tetraploid rice upregul express osamya osamyd result sharp increas amylas activ water absorpt sucros fructos content result seed vigour greater parent result indic addit research physiolog molecular featur indica japonica tetraploid rice seed germin respons ioniz radiat need
|
D012275
|
T168;T002
|
36,284,170
|
glial cell reactiv oxid stress prevent alzheim diseas mice model optim nmda receptor antagonist alzheim diseas patholog sever neuron process dysregul excitotox includ neuroinflamm oxid stress os new therapeut agent capabl modul process need foster neuroprotect effect optimis nmda receptor antagonist ub alt ev memantin gold standard evalu xfad mice follow treatment ub alt ev memantin chang calcineurin nfat pathway detect ub alt ev increas neurotrop factor bdnf vgf ngf gene express treatment reduc astrocyt microgli reactiv reveal glial fibrillari acid protein gfap ioniz calcium bind adapt molecul iba quantif interest ub alt ev abl reduc gene express trem marker microgli activ nf b pro inflammatori cytokin il ifn ccl ccl regul ub alt ev treat mice memantin treat mice interest anti inflammatori marker migrogli phenotyp chitinas like ym arginas arg regul treatment ub alt ev sinc ino gene express decreas ub alt ev treatment qpcr array contain os relat gene perform found chang il il gpx ncf aox vim gene express ub alt ev henc result reveal robust effect neuroinflamm os process ub alt ev treatment surpass memantin effect xfad
|
D000544;D002688
|
T047;T126;T116;T048
|
36,284,169
|
predat impact threaten spur thigh tortois golden eagl main prey scarc reduct adult surviv long live speci may compromis popul growth rate spur thigh tortois testudo graeca long live reptil threaten habitat loss fragment golden eagl aquila chrysaeto whose breed habitat overlap tortois may predat drop onto rock break carapac se spain number golden eagl increas last decad abund main prey ie rabbit oryctolagus cuniculus decreas aim describ role tortois golden eagl diet estim predat impact golden eagl tortois eagl territori region tortois popul collect regurgit pellet prey remain eagl nest roost obtain inform tortois abund popul structur rabbit abund found tortois altern prey rabbit eagl shift former latter scarc averag predat rate tortois low two studi scale howev eagl show mark select adult femal tortois led tortois sex ratio bias toward male eagl territori higher tortois predat whether may compromis spur thigh tortois long term popul viabil local deserv attent
|
D014426;D020307
|
T014;T012
|
36,284,167
|
data driven identif heart failur diseas state progress pathway use electron health record heart failur hf lead caus morbid healthcar cost mortal guidelin base segment hf distinct subtyp coars unlik reflect heterogen etiolog diseas trajectori patient analys electron health record show promis expand understand complex syndrom like hf evid driven way limit data qualiti present challeng larg scale ehr base insight generat decis make present hypothesi free approach generat real world characterist progress pattern hf patient diseas state snapshot extract complaint mention unstructur clinic note typic diseas state generat cluster character term distinguish featur tempor relationship risk import clinic event analysi generat comprehens diseas phenom real world patient comput larg noisi secondari use ehr dataset creat routin clinic set
|
D057286;D006333
|
T047;T170;T073;T046
|
36,284,166
|
direct model gps data reveal daili activ depend effect reproduct number covid pandem covid pandem govern face difficulti implement mobil restrict measur clear quantit relationship human mobil infect spread larg citi known develop model enabl quantit estim infect risk individu place activ use smartphon gps data tokyo metropolitan area effect reproduct number direct calcul number infecti social contact defin squar popul densiti locat differ infect rate daili activ consid stay activ stay someplac neither home workplac time larger activ also contribut infect strong depend locat impli effect reproduct number suffici suppress highest risk locat activ restrict also discuss effect delta variant vaccin
|
D000086382
|
T047;T067
|
36,284,165
|
chromosom scale genom assembl provid insight molecular mechan tissu develop populus wilsonii populus wilsonii import speci section leucoid natur popul main grow southwest china studi singl genotyp wild p wilsonii sequenc assembl genom size mb chromosom contig n mb total gene annot genom annot repetit element phylogenet analysi identifi diverg p wilsonii ancestor p deltoid p trichocarpa mya dtv ks distribut support occurr salicoid wgd event mya high conserv collinear support close evolutionari relationship among speci key enzym encod gene famili relat biosynthesi lignin flavonoid expand high express stem leav probabl resist damag natur environ addit key gene famili relat cellulos biosynthesi high express stem account high cellulos content p wilsonii varieti find provid deep insight genet evolut p wilsonii contribut biolog research breed well poplar salicacea
|
D032107
|
T002
|
36,284,164
|
attent modul interhemispher symmetri children development languag disord natur auditori process problem children development languag disord dld still poor understood much research devot determin extent dld associ general auditori versus languag specif dysfunct howev less emphasi given role differ task condit dysfunct explor whether children dld demonstr atyp interhemispher asymmetri auditori process speech non speech sound whether interhemispher balanc modul attent magnetoencephalographi use record auditori evok field children year old dld languag typic develop activ passiv listen speech non speech sound linear mix model analysi reveal bilater effect attent group particip dld demonstr atyp interhemispher asymmetri specif later ms time window passiv listen condit activ task dld group differ typic develop children term hemispher balanc activ result support idea alter interhemispher balanc passiv auditori respons properti dld suggest activ task condit top attent help regain leftward later particular later stage activ studi highlight high dynam interhemispher natur auditori process may contribut variabl report auditori languag process deficit dld
|
D007805
|
T033;T047;T048
|
36,284,163
|
impact self report sensori impair cognit function use korean longitudin studi age survey data recent studi suggest sensori impair relat cognit function older age therefor aim investig impact sensori impair cognit function korean popul use korean longitudin studi age data cognit function measur korean version mini mental state examin scale score time assess defin cognit impair sensori impair assess accord self report level hear vision develop sensori impair investig use record prior survey use general estim equat model determin associ cognit function sensori impair total particip age rang year mean age includ studi compar peopl without sensori impair peopl singl sensori impair hear vision higher risk cognit impair odd ratio confid interv ci peopl dual sensori impair greatest risk cognit impair ci find suggest need time assess sensori function older person may use identifi individu risk cognit impair
|
D034381;D060825
|
T033;T047;T048
|
36,284,162
|
chromosom scale genom assembl brown anol anoli sagrei emerg model speci rapid technolog improv democrat access high qualiti chromosom scale genom assembl longer domain high studi model organ non tradit emerg model speci genom enabl use combin sequenc technolog assembl softwar consequ old idea built spars sampl across tree life recent amend face genom data drawn grow number high qualiti refer genom arguabl valuabl long studi speci much alreadi known biolog mani term emerg model speci report high complet chromosom scale genom assembl brown anol anoli sagrei lizard speci wide studi across varieti disciplin high qualiti refer genom long overdu assembl exceed vast major exist reptil snake genom contigu n mb annot complet analysi genom popul resequ data examin histori repetit element accumul identifi x chromosom propos hypothesi evolutionari histori fusion autosom x led sex chromosom sagrei
|
D008116
|
T014
|
36,284,161
|
phylogenom reveal evolut biogeographi diversif histori vole hengduan mountain hengduan mountain hdm china biodivers hotspot whose temper flora fauna among world richest howev origin evolut biodivers hdm remain poor understood especi mammal given hdm show highest rich vole speci world use whole exom captur sequenc data current comprehens sampl hdm vole investig evolutionari histori diversif pattern reconstruct robust phylogeni estim diverg time hdm vole found hdm vole could divid western lineag volemi proedromi neodon eastern lineag caryomi eothenomi two lineag origin two migrat event north eurasia hdm approxim mya vole lineag underw signific acceler net diversif mya tempor congruent orogeni hdm region also identifi strong intertrib gene flow among hdm vole hypothes frequent gene flow might facilit speciat burst hdm vole studi highlight import environment biotic factor shape biodivers mammal mountain ecosystem
|
D003411;D017753
|
T015;T070;T082
|
36,284,160
|
pool imag base screen mitochondria microraft isol distinguish pathogen mitofusin mutat human genet variat classifi variant uncertain signific advanc genom edit allow innov pool screen platform mani screen deal relat simpl readout viabil fluoresc identifi complex cellular phenotyp underli human diseas paper present generaliz function genom platform combin high content imag machin learn microraft isol method term raft seq highlight efficaci platform show abil distinguish pathogen point mutat mitochondri regul mitofusin even cellular phenotyp subtl also show platform achiev efficaci use multipl cellular featur configur fli raft seq enabl way perform pool screen set mutat biolog relev cell abil physic captur cell perturb phenotyp expand clonal direct primari screen
|
D000072669;D023281
|
T063;T091
|
36,284,157
|
face mask use categor dimens social percept prevent measur aim combat covid pandem strong impact sever aspect social life particular interperson percept affect function whether person perceiv wear face mask two experiment studi explor whether peopl reli presenc vs absenc face mask encod inform memori individu memori confus paradigm particip initi present individu either wear face mask convey seri sentenc next particip probe ident speaker sentenc result show like erron attribut sentenc speaker also wear face mask origin speaker demonstr cue wear face mask spontan use encod inform studi rule altern explan base perceptu process suggest face mask repres meaning social object overal emerg particip spontan categor other function whether wear mask find also confirm previous research evid posit evalu mask wearer compar non wearer overal detriment impact face mask may correct identif social target
|
D008397;D000086382
|
T047;T074;T067
|
36,284,155
|
top modul impair prime suscept complex decis make social implic could social context variabl prime complex decis could top process impair prime suscept complex decis main studi econom moral perspect dual process theori provid evid process could affect address issu polit perspect onlin experi conduct particip n ask choos face option associ differ frequenc repetit prime phrase differ emot valenc emot prime unspecifi task ust group import task imt group repeat face chosen ust group associ lower respons time posit face equal chosen group compar result ecolog situat social studi conduct argentin presidenti elect includ onlin survey n analysi news media mention candid familiar trust candid explain vote probabl well correl frequenc mention news posit associ elect result result suggest complex decis make suscept prime depend top modul
|
D021641;D004644
|
T041
|
36,284,154
|
effect shadi environ fish collect behavior despit signific effort devot understand under complex emerg collect movement anim group role differ extern set type movement remain larg unexplor combin time seri analysi complex network tool present extens investig effect shadi environ behavior fish speci silver carp hypophthalmichthi molitrix within earthen pond find shade encourag fish resid daylight hour degre prefer shade vari substanti among trial pond silver carp much slower exhibit lower persist speed shade daytim nighttim fish display highest persist degre speed night furthermor research show shade affect fish school behavior reduc polar number interact among individu stabil among local neighbor howev fish keep higher local degre order shade compar nighttim posit
|
D000090522;D002347
|
T054;T013
|
36,284,153
|
inhibit rhorock signal pathway particip cardiac protect exercis train spontan hypertens rat exercis train ext capabl improv heart function spontan hypertens rat shrs under molecular mechan remain elus studi aim investig whether inhibit rhoarock signal pathway contribut cardiac protect low intens ext shrs result demonstr compar wistar kyoto wki rat shrs obvious exhibit higher blood pressur increas heart weight index thick left ventricular wall decreas left ventricular function damag myocardi construct increas collagen fiber left ventricl p p meanwhil mrna protein express level rhoa rock heart shrs signific increas compar wki rat p p interest patholog chang heart aforement improv shr ext rat compar shr sed rat p p indic cardiac protect exercis train addit cardiac protect effect exercis train could block lpa activ rhorock signal protect effect shr rat could mimick fasudil inhibitor rhorock signal result strong suggest low intens ext protect heart structur function inhibit rhorock signal pathway hypertens rat
|
D006973
|
T047
|
36,284,151
|
first hepat e outbreak southeastern seneg rapid prolifer tradit gold mine site kedougou region led massiv migrat peopl neighbour west african countri establish sever small villag poor hygien sanit condit exist context hepat e virus outbreak report kedougou sever case among tradit mine worker herein describ epidemiolog laboratori data collect outbreak investig februari novemb suspect contact probabl case investig clinic epidemiolog data collect studi sera collect test viral rna anti hepat e virus hev igm archiv serum sampl kedougou retrospect screen real time polymeras chain reaction rt pcr enzym link immunosorb assay elisa total water sampl collect pond well surround gold panner site habitat tissu sampl rat captur environ tradit gold mine site also test total sera collect suspect case contact person miss inform median age year old sex ratio overal rate patient test posit hev high case fatal rate pregnant women water sampl anim tissu test negat hev data help determin begin hev outbreak march also identifi risk factor associ emerg howev need implement routin diagnosi surveil train health personnel order reduc mortal especi among pregnant women addit studi need identifi virus reservoir environment risk factor hev kedougou region
|
D016751;D016752
|
T047;T005
|
36,284,149
|
subalpin woodi veget eastern carpathian releas agropastor pressur subalpin veget eastern carpathian agropastor influenc high mountain open pastur five centuri today subalpin zone releas human intervent grow thicket studi use numer model tree crown chm canopi height model base laser scan lidar high resolut digit terrain model dtm delin subalpin thicket distribut anselin local moran statist use find hot cold spot veget cover use logist general linear model glm princip compon analysi pca set histor climat terrain condit candid predictor present day distribut veget hot spot use varianc partit assess interact climat terrain variabl result model suggest key environment control underli veget pattern name snow terrain depress protect woodi veget abras winter drought increas insol reduc site humid summer e exposur hamper veget addit increas distanc treelin declin rate secondari success spatial model predict coverag thicket theoret maximum avail climat terrain nich result suggest growth subalpin thicket face grow global temperatur may restrict due limit number nich avail
|
D044822;D014197
|
T002;T080
|
36,284,144
|
novel metagenom deriv viral rna polymeras applic cell free express system metagenom screen mine genom non cultiv microorgan use metagenom power tool discov novel protein valuabl biomolecul howev function base metagenom search often limit time consum express activ protein various heterolog host system report initi character novel singl subunit bacteriophag rna polymeras em rnap identifi metagenom data set obtain eleph dung microbiom em rnap promot sequenc distant relat rna polymeras use em rnap translat compet escherichia coli extract develop effici medium throughput pipelin protocol allow express metagenom deriv gene product protein cell free system suffici initi test predict activ success identifi verifi enzym act bis hydroxyethyl terephthal bhet complet clone free approach propos vitro high throughput metagenom screen method
|
D054892;D000086902
|
T126;T116;T028
|
36,284,143
|
common resist mechan deploy plant sap feed herbivor insect insight meta analysi systemat review despit abund econom import mechan plant resist sap feed insect remain poor understood deploy meta analysi data synthesi method evalu result electrophysiolog studi describ feed behaviour experi resist mechan identifi focuss studi describ host plant resist non host resist mechan data extract studi compris insect speci across eight insect taxa host plant famili repres speci result demonstr mechan deploy resist plant common consequ feed behaviour divers insect group show insect feed resist plant take longer establish feed site feed durat suppress two fold compar insect feed suscept plant result reveal trait contribut toward resist phenotyp conserv across plant famili deploy taxonom divers insect group under resist mechan conserv find provid new insight plant insect interact highlight need mechanist studi across divers taxa
|
D060434;D007313
|
T040;T008;T204
|
36,284,139
|
cone oppon function domain primari visual cortex combin signal color appear mechan studi color percept led mechanist model cone oppon signal retin ganglion cell integr generat color appear unknown hypothes integr occur brain show cone oppon signal transmit retina primari visual cortex v integr high organ circuit within v implement color oppon interact requir color appear combin intrins signal optic imag isi photon calcium imag pci singl cell resolut demonstr cone oppon function domain cofd combin lm cone oppon sl cone oppon signal follow rule predict psychophys studi color percept give rise order organ hue prefer neuron within cofd generat hue pinwheel thus spatial organ neural circuit mediat order transit cone oppon color appear begin v
|
D002118;D000087642
|
T123;T196;T121;T029
|
36,284,137
|
associ altitud serum folat level tibetan adult tibetan plateau studi investig relationship resid altitud serum folat level healthi tibetan live tibetan plateau particip select underw physic examin health center novemb februari demograph characterist medic histori collect fast blood test serum folat hematolog indic relationship altitud serum folat level analyz use multivari linear regress model serum folat level associ altitud confid interv ci hemoglobin ci red blood cell ci hematocrit ci high densiti lipoprotein cholesterol ci sex ci multivari linear regress analysi reveal altitud negat associ serum folat level adjust confound factor serum folat level decreas ngml per increas altitud ci p altitud negat associ serum folat level tibetan adult relationship altitud folat level explor popul differ race diseas state larg scale prospect studi illustr causal relationship
|
D000531;D006454
|
T081;T123;T116
|
36,284,136
|
individu generat valu chang adult popul year longitudin panel studi long stand conundrum whether age differ person due generat intern chang age use repres sampl netherland n age start current research focus human valu import aspect person follow individu year distinguish four generat silent generat babi boomer generat x millenni found clear differ across generat human valu millenni eg valu hedon generat furthermor valu chang time main evid millenni valu achiev conform stabl within individu generat chang time across valu occur main millenni valu valu stabl adult eg hedon conform valu still increas eg secur self direct decreas eg power stimul import adult older millenni chang decreas chang absent oldest generat henc age differ valu seem due generat well intern chang although latter main young adult valu chang time may implic develop societ valu long run
|
D012919;D010684
|
T078;T090;T054
|
36,284,135
|
summit integr approach better transcriptom data imput improv causal gene identif gene moder low express herit may explain larg proport complex trait etiolog gene suffici captur convent transcriptom wide associ studi twass part due relat small avail refer dataset develop express genet predict model captur moder low genet regul compon gene express introduc method summari level unifi method model integr transcriptom summit improv express predict model accuraci power twas use larg express quantit trait loci eqtl summari level dataset appli summit eqtl summari level data provid eqtlgen consortium simul studi analys genom wide associ studi summari statist complex trait show summit improv accuraci express predict blood success build express predict model gene low express herit achiev higher statist power sever benchmark method final conduct case studi covid sever summit identifi like causal gene associ covid sever
|
D059467;D000086382
|
T081;T047;T067;T086
|
36,284,133
|
associ stunt wast month age development mileston delay cohort cambodian children worldwid million children year reach development potenti due sever caus includ malnutrit cambodia preval stunt wast among children remain high prospect cohort studi aim assess acquisit motor cognit development mileston earli childhood associ stunt wast children age month recruit three provinc cambodia follow seven time march june year data collect includ anthropometri development mileston seven motor seven cognit mileston evalu use cambodian develop mileston assess tool associ assess parametr surviv model hazard ratio hr stood lower probabl achiev development mileston data avail children month preval stunt wast respect consist associ delay motor cognit mileston stunt strong associ delay gross motor mileston hr p wast strong associ delay fine motor develop cognit mileston hr p promot nutrit program first day prevent malnutrit essenti optim growth motor cognit develop cambodian children
|
D006130;D044342
|
T047;T046
|
36,284,132
|
call amino acid sequenc proteinpeptid nanospectrum produc sub nanomet diamet pore blockad current develop protein transloc across thin membran sub nanomet diamet pore inform extrem sensit sequenc amino acid constitut protein current blockad signal measur transloc call nanospectrum protein wherea mass spectrometri ms still domin technolog protein identif suffer limit proteom wide studi ms identifi protein databas search often fail provid high protein sequenc coverag also sensit requir femtomol protein identif compar ms sub nanomet diamet pore ie sub nanopor direct read amino acid constitut singl protein molecul effici comput tool still requir process interpret nanospectra delin comput method process sub nanopor nanospectra predict theoret nanospectra protein sequenc essenti protein identif
|
D020543;D058608
|
T123;T116;T082
|
36,284,131
|
induct distinct plant cell death program secret protein wheat pathogen zymoseptoria tritici cell death process eukaryot shape normal develop respons environ plant microb interact initi host cell death play import role determin diseas outcom cell death pathway frequent initi follow detect pathogen deriv molecul lead resist suscept diseas depend pathogen lifestyl previous identifi sever small secret protein ssps wheat infect fungus zymoseptoria tritici induc rapid cell death nicotiana benthamiana follow agrobacterium mediat deliveri express agroinfiltr investig whether execut host cell mechanist similar respons differ z tritici ssps use rna sequenc found transient express four z tritici ssps led massiv transcript reprogram within h agroinfiltr observ distinct host gene express profil induc depend whether cell death occur cell surfac immun receptor depend independ manner gene express profil involv differenti transcript network mediat wrki nac myb transcript factor addit differenti express gene belong differ class receptor like protein receptor like kinas observ data suggest differ z tritici ssps trigger differenti transcript reprogram plant cell
|
D010935;D001203
|
T047;T004
|
36,284,130
|
cognit penetr scene represent base horizont imag dispar structur natur scene signal mani visual cue princip amongst binocular dispar creat later separ viewpoint two eye dispar cue believ process hierarch first term local measur absolut dispar second term global measur relat dispar allow extract depth structur scene psychophys oculomotor studi suggest relat dispar particular relev percept whilst absolut dispar compar neural respons stimuli isol absolut dispar cue stimuli contain addit relat dispar cue use high tempor resolut eeg determin tempor order absolut relat dispar process vari observ task assess extent cue cognit penetr find absolut dispar extract relat dispar task effect aris extract relat dispar result indic hierarchi dispar process stage lead format proto object represent upon higher cognit process act
|
D003867;D015357
|
T081;T041
|
36,284,129
|
genom wide associ map wheat morphometr seed trait iranian landrac cultivar rain fed well water condit seed trait bread wheat valuabl breeder farmer thus import explor putat qtls respons key trait use breed program gwas carri use bread wheat landrac cultivar iran uncov genet basi seed characterist rain fed well water environ analys linkag disequilibrium ld marker pair show largest number signific lds landrac cultivar record genom b strongest ld identifi chromosom ld decay higher b genom compar genom map use mrmlm lod mlm bonferroni led marker trait associ mtas rain fed well mtas well water condit respect studi found vmrmlm correct detect type loci estim effect unbias manner high power accuraci low fals posit rate led identif mtas lod environ gene ontolog reveal mtas found protein code region rain fed well water condit respect find suggest landrac studi iranian bread wheat germplasm possess valuabl allel respons water limit condit mtas uncov studi exploit genom mediat develop novel wheat cultivar
|
D014908;D055106
|
T063;T168;T002
|
36,284,128
|
combin long read short read sequenc provid comprehens transcriptom new insight chrysanthemum morifolium ray floret color chrysanthemum morifolium one popular ornament plant global owe larg complex genom around gb segment hexaploid difficult obtain comprehens transcriptom promot perform new breed techniqu genom edit c morifolium studi use singl molecul real time smrt sequenc rna seq technolog combin error correct process obtain high coverag ray floret transcriptom smrt seq data increas ratio long mrnas contain complet open read frame combin dataset provid complet transcriptom data produc either smrt seq rna seq deriv transcript final obtain sei arabella transcript contain non redund mrna show benchmark univers singl copi ortholog busco score also valid reliabl dataset analyz map rate annot transcript express use dataset search anthocyanin biosynthesi gene ortholog perform qrt pcr experi assess usabl dataset assess dataset follow analysi indic dataset reliabl use molecular biolog combin sequenc method provid genet inform way analyz complic c morifolium transcriptom
|
D031202
|
T002
|
36,284,127
|
pierc suck mouth part sensilla irradi mosquito culex pipien diptera culicida gamma radiat morpholog distribut function sensilla associ mouthpart femal mosquito culex pipien diptera culicida studi use scan electron microscop femal mosquito mouthpart pierc suck type carri mani sensori organ play major role host seek oviposit behaviour mosquito six type mouthpart sensilla identifi describ sensilla trichoidea chaetica basiconica capit peg campaniformia squamiformia femal mosquito irradi pupa gy gamma radiat investig effect mouthpart sensilla dose gy slight effect differ type sensilla compar control featur malform observ maxillari palp segment radiat dose includ fall scale sensilla squamiformia certain part st segment leav vacuol gy maxillari palp segment liquefi area leav undistinguish shape highest dose gy tip labial palp mani tear show affect especi trichoid basicon chateica sensilla malform may lead mosquito reach host imped abil transmit diseas kill mosquito main object studi
|
D004175;D003465;D009033
|
T204
|
36,284,126
|
effect fatigu electromechan respons time basketbal player without persist low back pain typic athlet alter movement mechan presenc back pain effect chang lower extrem injuri risk well understood studi aim compar effect fatigu electromechan respons time choic reaction task basketbal player without persist low back pain twenti four male basketbal player particip total reaction time trt premotor time pmt electromechan delay emd data record fatigu chronic low back pain clbp group signific longer emd med gastrocnemius p tibiali anterior p shorter emd vastus laterali p vastus mediali obliqu p semitendinosus p muscl fatigu pmt clbp group longer non clbp vastus laterali p vastus mediali obliqu p semitendinosus p also trt longer knee flexion p ankl plantarflexion p muscl group differ effect fatigu electromechan respons time knee ankl peopl clbp may repres effect axial injuri lower extrem injuri risk factor situat higher cognit load similar competit play
|
D017116;D001490
|
T184;T047;T073;T056
|
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