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biomedical-topic-categorization-validation

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36,283,746
health inform use patient system lupus erythematosus sle pre covid pandem conduct intern survey patient sle assess access prefer trust various health inform sourc pre covid covid pandem
D000086382;D008180;D061108
T047;T170;T067
36,283,745
impact sever infect sle observ studi spanish nation registri infect common complic sle object evalu caus impact surviv patient sle
D008180
T047
36,283,740
intraop discoveri melanosi coli emerg bowel resect perfor patient taken oper room presumpt diagnosi necrot small bowel colon procedur note black mucosa throughout colon sever factor suggest viabl colon tissu decis made resect colon origin plan final patholog specimen would later reveal melanosi coli ultim benign diagnosi question patient found taken herbal laxat supplement contain sever compon known caus melanosi coli hope case report serv remind surgeon clinician rememb melanosi coli clinic entiti confront blacken darken colon mucosa review avail literatur identifi case melanosi coli discov intraop propos number factor support intraop decis make
D003108;D008548
T033;T047
36,283,735
tumor mhc class express alter cancer associ myelopoiesi driven host nk cell downregul mhc class mhci molecul tumor cell recogn resist mechan cancer immunotherapi given mhci molecul potent regul immun respons postul express mhci tumor cell influenc system immun respons accord mice bear mhci defici tumor cell show reduc tumor associ extramedullari myelopoiesi spleen deplet natur killer nk cell abrog differ suggest integr role immun regulatori nk cell tumor progress cytokin profil reveal upregul tnf nk cell tumor spleen mice bear mhci express tumor inhibit tnf enhanc host myelopoiesi mice receiv adopt transfer tumor experienc nk cell studi highlight critic role nk cell beyond ident killer lymphocyt import potenti host respons local tumor determin mhci express
D038042;D009369
T191;T042
36,283,734
systemat comparison autoimmun liver diseas identifi specif histolog featur immun checkpoint inhibitor relat advers event immun checkpoint inhibitor ici becom mainstay cancer treatment immun boost qualiti one major drawback procliv induc broad array immun relat advers event ira affect among other liver share similar classic autoimmun liver diseas aild aim compar clinic laboratori histolog featur patient liver relat ira aild
D000074322;D009369;D007154;D008107;D019693
T129;T121;T116;T191;T033;T047
36,283,732
develop implement matern child health handbook angola although matern child health mch handbook wide use mani countri develop implement process suffici document scientif public report angola mch handbook develop challeng encount implement solv lead process mch handbook committe set develop mch handbook implement programm liaison various stakehold develop mch handbook participatori workshop object produc user respons content design foster healthi interact build common understand among stakehold pilot use select health facil mch handbook programm includ train monitor supervis mother class communiti awar rais activ gradual implement three model provinc core member committe close observ step programm identifi challeng field revis tool programm throughout process nationwid implement mch handbook programm progress import continu identifi challeng specif differ local take measur address experi stakehold involv earli plan prepar stage critic ensur continu commit later stage programm continu approach tool develop involv various stakehold flexibl implement strategi key element user accept programm sustain may applic introduct similar intervent set
D000067576
T078;T058
36,283,731
build network sentinel centr care women abort situat advanc latin america caribbean previous report alreadi estim overal number abort number unsaf abort latin america convers reliabl data region inform public polici aim meet women need context latin american centr perinatolog centro latinoamericano de perinatologa clap creat network specialis care women abort situat clap musa network attempt strengthen healthcar surveil latin america use perinat inform system sistema informtico perinat sip system develop clap special modul name sip abort sip data collect tool design latin american expert routin use case legal incomplet abort sip follow standard establish allow investig systematis inform generat local report monitor chang train follow intervent base nation guidelin network promot collabor work institut strengthen epidemiolog surveil cooper investig develop critic mass profession skill sexual reproduct health current sentinel centr countri joint work exchang inform improv surveil healthcar indic women abort situat latin america first region world network sentinel centr continu monitor healthcar provis women data collect network alreadi use design implement evalu public polici
D003906;D000028
T061;T080;T093;T033;T081;T046
36,283,723
label use adult palliat care common expect retrospect chart review label drug use seem integr adult palliat care pharmacotherapi balanc potenti risk benefit context limit therapeut option challeng provid specif support clinician deal label use essenti understand label use everyday clinic practic aim pilot studi quantifi describ label use adult palliat care unit
D010166;D056687
T061;T037
36,283,714
recommend anatom structur identifi ultrasound perform intermedi advanc block ultrasound guid region anesthesia recent recommend describ set core anatom structur identifi ultrasound perform basic block ultrasound guid region anesthesia ugra project aim generat consensus recommend core structur identifi perform intermedi advanc block initi longlist structur refin intern panel key opinion leader ugra three round delphi process round conduct virtual anonym block consid twice round orient scan dynam process acquir final view block view visual block site maintain needl insertioninject strong recommend made particip rate structur definit includ round weak recommend made particip rate definit includ probabl includ round criterion strong recommend never met structur meet either criterion exclud forti one particip invit accept complet three round particip consid ultrasound scan peripher nerv block across three round two hundr seventi four structur review orient scan block view strong recommend made structur orient scan block view weak recommend made structur respect recommend intend help standard teach research ugra support widespread consist practic
D018084;D000765
T060;T061
36,283,713
comparison sit prone posit real time ultrasound guid thorac epidur cathet placement random control trial real time ultrasound guid thorac epidur cathet placement us tecp recent introduc patient posit associ success spine intervent howev effect posit outcom procedur remain unknown aim assess clinic use patient posit real time us tecp
D000073818;D000767
T061;T184
36,283,712
nerv stimul guid bilater pudend nerv block versus landmark base caudal block hypospadia repair young children prospect random pragmat trial caudal block frequent perform provid analgesia hypospadia repair literatur suggest pudend block provid prolong postop analgesia compar caudal block children year compar efficaci pudend caudal block children less year
D060525;D007021;D009407
T061;T019;T023
36,283,709
obes alon rule knee replac surgeri studyevan jt mouchti blom aw et al obes revis surgeri mortal patient report outcom primari knee replac surgeri nation joint registri uk cohort studi plos med
D019645
T061
36,283,705
use link registri claim data long term surveil devic endovascular abdomin aortic aneurysm repair observ surveil studi evalu long term outcom reintervent late ruptur abdomin aortic aneurysm aortic endograft real world practic use link registri claim data
D017544;D019917;D057510
T061;T047
36,283,704
stepwis progress select cell develop involv histon deacetyl cell develop first step creat uniqu cell receptor tcr genet recombin tcr chain qualiti new tcr assess select checkpoint cell fail checkpoint die coordin fate select checkpoint yet understood shed new light fate determin select use select inhibitor histon deacetylas aci aci disrupt select checkpoint characteris basi disrupt reveal new pivot stage select bookend regul tcr co receptor cd cd respect within dnb pre stage cd lef regul reflect pre tcr signal express correl prolifer find suggest refin model select coordin increas express pre tcr cd cd lef allow modul tcr signal strength culmin express cd enabl exit select checkpoint
D018106;D016693
T129;T116;T192
36,283,703
high content endogen glut traffick assay reveal new aspect adipocyt biolog insulin induc glut transloc plasma membran muscl adipocyt crucial whole bodi glucos homeostasi current glut traffick assay reli overexpress tag glut describ high content imag platform studi endogen glut transloc intact adipocyt method enabl high fidel analysi glut respons specif perturb multiplex traffick protein featur includ lipid droplet morpholog use multiplex approach show vps rab select regul glut trarg stx stx tbcd rab knockdown affect glut tfr transloc thus glut tfr transloc machineri like overlap upon insulin stimul addit identifi kifa rab bind molecular motor novel regul glut traffic final comparison endogen overexpress glut highlight endogen glut methodolog enhanc sensit genet perturb emphasis advantag studi endogen protein traffick drug discoveri genet analysi insulin action relev cell type
D020691;D017667
T126;T116;T025
36,283,702
profil subcellular local nuclear encod mitochondri gene product zebrafish mitochondri protein encod nuclear gene synthet cytosol target organell character spatial organ mitochondri gene product zebrafish danio rerio sequenc rna differ cellular fraction result confirm presenc nuclear encod mrnas mitochondri fraction unperturb condit main transcript encod larg protein specif properti like transmembran domain explor principl mitochondri protein compartment zebrafish quantifi transcriptom chang subcellular fraction trigger chchda mutat caus disord mitochondri protein import result indic proteostat stress restrict popul transcript mitochondri surfac allow largest evolutionari conserv protein synthet also show mani nuclear encod mitochondri transcript translat cytosol ribosom stay resist global translat shutdown thus vertebr contrast yeast like use local translat facilit synthesi mitochondri protein proteostat stress condit
D015027;D050259
T045;T028;T013
36,283,699
report mja lancet countdown health climat chang australia unprepar pay price mja lancet countdown health climat chang australia establish produc first nation assess annual updat examin five broad domain climat chang impact exposur vulner adapt plan resili health mitig action health co benefit econom financ public polit engag fifth year mja lancet countdown track progress extens suit indic across five domain access present latest data refin develop analys within two year australia experienc two unpreced nation catastroph summer heatwav bushfir torrenti rain flood event cost live displac ten thousand peopl analysi show clear sign australia health emerg manag capac substanti decreas find sign progress respect health climat chang state continu lead way health climat chang adapt plan victorian plan publish earli nation level note progress health climat chang research fund nation health medic research council also see acceler uptak electr vehicl continu uptak employ renew energi howev also find australia transit renew zero carbon remain unaccept slow australian govern continu failur produc nation climat chang health adapt plan place health live australian unnecessari risk today bode well futur
D057231;D059205
T070;T169
36,283,698
canadian centr experi prone retroperitoneoscop adrenalectomi minim invas adrenalectomi standard care surgic manag benign adren diseas transperiton laparoscop approach tla common approach use worldwid howev mani centr adopt posterior retroperitoneoscop approach pra report offer sever advantag describ experi pra
D000310;D010535
T060;T191;T061
36,283,697
simultan versus rapid serial intervent hybrid oper suit sever injur patient prospect evalu differ raptor techniqu outcom open surgic percutan endovascular procedur aim arrest traumat life threaten hemorrhag usual perform rapid serial fashion surgeon intervent radiologist truli simultan procedur requir modif techniqu workflow team collabor primari object studi prospect audit outcom patient ongo hemorrhag underw truli simultan open percutan procedur
D020304
T012
36,283,693
gene recruit dismiss argonaut genom provid insight pelag lifestyl adapt shell like eggcas reacquisit paper nautilus greater argonaut argonauta argo speci octopod character pelag lifestyl presenc protect spiral shape shell like eggcas femal reveal genom background speci adapt pelag lifestyl acquir shell like eggcas sequenc draft genom speci genom size gb smallest among cephalopod known date top scaffold averag length bp cover gb total assembl total protein code gene predict assembl scaffold identifi near intact hox parahox wnt cluster gene cluster could probabl relat pelag lifestyl reflectin tyrosinas opsin gene model also reveal sever homolog gene relat calcifi shell format conchiferan mollusk pif like sod trx interest compar genom analysi reveal homolog gene gene also found genom shell less octopus well nautilus true outer shell therefor draft genom sequenc arg argo present help us gain insight genet background dynam recruit dismiss gene form import converg extend phenotyp structur shell shell like eggcas addit allow us explor evolut benthic pelag lifestyl cephalopod octopod
D016678;D008974
T204;T028
36,283,692
structur basi flagellar motil regul mogr repressor gmar antirepressor listeria monocytogen pathogen listeria monocytogen bacterium produc flagellum locomot organell c outsid host halt flagellar express c insid human host evad flagellum induc immun respons listeria monocytogen gmar thermosensor protein coordin flagellar express bind master transcript repressor flagellar gene mogr temperatur respons manner understand regulatori mechan wherebi gmar exert antirepress activ flagellar express perform structur mutat analys gmar mogr system c gmar exist function monom form circular enclos multidomain structur via interdomain interact gmar conform recogn mogr use c termin antirepressor domain uniqu dual bind mode mediat antirepressor function direct competit spatial restraint mechan surpris c gmar rapid form autolog aggreg defici mogr neutral capabl
D008089
T007
36,283,691
enhanc high thermal conduct cellulos filament via hydrodynam focus nanocellulos regard green renew nanomateri attract increas attent studi demonstr nanocellulos materi exhibit high thermal conduct nanofibril high align bond form filament thermal conduct individu filament consist high align cellulos nanofibril fabric flow focus method measur dri condit use type measur techniqu maximum thermal conduct nanocellulos filament obtain wm k approxim five time higher cellulos nanopap cellulos nanocryst structur investig suggest crystallin filament remark influenc thermal conduct smaller diamet filament higher crystallin internanofibril hydrogen bond less intrananofibril disord tend higher thermal conduct temperatur depend measur also reveal filament exhibit phonon transport effect dimens
D049329;D053758
T073
36,283,683
intrahospit protocol manag covid diseas adult covid pandem current respons million infect million death new diseas number paper subject extens motiv consider heterogen approach despit medicin sound evid benefit new intervent strategi continu propos still lack scientif evid hinder uniform consensu approach articl aim standard healthcar adult patient moder critic covid emerg depart hospit either general ward level level intens care unit base best updat scientif evid avail protocol present recommend stratif adult patient covid diseas adequ workup admiss hospit inpati treatment criteria general treatment measur pharmacolog treatment manag complic organ pneumonia bacteri superinfect thromboprophylaxi special consider pregnanc breastfeed possibl futur therapi
D000086382;D054556
T047;T067
36,283,679
brumir toolkit de novo discoveri microrna srna seq data microrna mirna small noncod rnas key player regul gene express past decad increas access high throughput sequenc technolog differ method develop identifi mirna reli preexist refer genom howev refer genom absent high qualiti identif becom difficult context develop brumir algorithm abl discov mirna direct exclus small rna srna sequenc srna seq data benchmark brumir dataset encompass anim plant speci use real simul srna seq experi result demonstr brumir reach highest recal mirna discoveri time much faster effici state art tool evalu latter allow brumir analyz larg number srna seq experi plant anim speci moreov brumir detect addit inform regard express sequenc srnas isomir etc thus maxim biolog insight gain srna seq experi addit refer genom avail brumir provid new map tool brumirrefer perform posteriori exhaust search identifi precursor sequenc final also provid machin learn classifi base random forest model evalu sequenc deriv featur refin predict obtain brumir core code brumir algorithm compos brumir toolkit freeli avail https githubcomcamoragaqbrumir
D035683;D058727
T123;T114
36,283,675
enhanc biohydrogen generat calcium peroxid engend effici ultrason disintegr wast activ sludg low temperatur environ wast activ sludg renew sourc biohydrogen product wherea presenc complex biopolym limit hydrolysi step process thus pretreat requir disintegr sludg biomass studi feasibl util wast activ sludg produc biohydrogen improv solubil mean thermo cao engend sonic disintegr tcp us studi optim condit extracellular polymer substanc ep dissoci obtain cao dosag gg ss c maximum disintegr ep remov achiev sonic specif energi input kjkg ts maximum solubil ss reduct respect higher us alon pretreat thus solubil yield higher biohydrogen product mlh gcod tcp us sampl
D012722;D014465
T070;T069
36,283,674
oliv mill wastewat liquid biolog wast carbonoxocalcium composit select effici remov methylen blue paracetamol aqueous solut studi carbonoxocalcium prepar oliv mill wastewat success appli remov paracetamol methylen blue mb aqueous medium optim composit cao rich anion site porous specif surfac area g adsorpt test show signific adsorpt capac mgg adsorpt mb paracetamol well describ redlich peterson dubinin radushkevich isotherm respect moreov adsorpt kinet fit pseudo second order interact hydrogen bond electrostat interact respons adsorpt paracetamol mb substrat work develop singl easi simpl action new effect select materi remov emerg pollut new method develop stabl carbon composit cost effect method valor oliv mill wastewat
D031658;D014874
T168;T131;T002
36,283,673
one pot bioprocess lignocellulos biorefineri review practic high yield convers biomass valu ad product low cost primari goal lignocellulos refineri industri context limit practic adapt convent techniqu practic involv multipl reactor convers biomass bioproduct therefor present manuscript critic review advanc one pot reaction system major focus scientif product valu ad product lignocellulos biomass view novelti one pot reaction shown fraction biomass individu constitu import direct convers cellulos lignin rang valuabl product includ organ acid platform chemic separ discuss final articl conclud opportun exist troubl possibl solut overcom challeng lignocellulos biorefineri articl assist reader identifi econom friend one pot convers lignocellulos biomass
D008031;D002482
T123;T122;T109
36,283,672
microbi carbon anhydras mediat carbon captur sequestr util sustain approach deliv bio renew recent scenario anthropogen intervent alarm disrupt climat condit persist chang climat necessit carbon neutral effici way carbon captur sequestr could employ sustain product generat carbon anhydras ca enzym revers catalyz convers carbon dioxid bicarbon ion util cell metabol process henc util ca microbi sourc carbon sequestr correspond deliveri bio renew could eco friend approach consequ microbi ca amin base carbon captur chemic synergist appli enhanc carbon captur effici eventu util review comprehend recent develop coupl engin techniqu especi microbi ca creat integr system co sequestr envisag develop sustain approach toward mitig environment co industri fossil fuel generat bio renew valu ad chemic
D002256
T126;T116
36,283,669
improv glycerol util high temperatur xylitol product kluyveromyc marxianus use transient cluster regular interspac short palindrom repeat crispr crispr associ protein system glycerol ideal co substrat xylitol product kluyveromyc marxianus studi demonstr k marxianus catabol glycerol gut gut pathway instead previous specul nadph depend gci dak pathway use transient cluster regular interspac short palindrom repeat crispr associ protein crisprca system addit utrp demonstr mediat nadph generat nadh phosphoryl yzb construct integr utr ypr site strain overexpress ncxyl cigxf harbor disrupt xyl exhibit enhanc glycerol util xylitol product gl consum gl glycerol fed batch ferment c yzb yield gl xylitol highest known xylitol titer obtain via biolog method feed crude glycerol xylos mother liquor corn steep liquor powder bioreactor result product gl xylitol studi develop platform xylitol product industri product
D014993;D007716
T121;T004;T109
36,283,668
control recoveri recycl carboxyl acid polyalcohol deep eutect solvent biomass pretreat electron control chemic methodolog pretreat lignocellulos biomass use deep eutect solvent des demonstr environment valid co exist donor acceptor hydrogen bond make des composit complic tradit solvent limit scale util advanc biomass pretreat use green solvent des excogit effici methodolog des recycl electron control chemic methodolog first put forward resolv recoveri recycl issu des lactic acid ethylen glycol biomass pretreat methodolog work base select migrat lactat lac reserv ethylen glycol use bp bp bipolar membran electrodialysi bmed impact primari factor des recoveri care studi lowest energi consumpt specif des recoveri reach kwhkg highest des recoveri rate approach cognit acquir research indic promis effici strategi carboxyl acid polyalcohol des recoveri novel electron control chemic methodolog
D008031;D000091463
T120;T123;T109
36,283,665
studi perform mechan bio electrochem system mitig membran foul bioreactor allevi membran foul membran membran bioreactor direct use anod bio electrochem system th day control group block experiment group current increas tmp kpa polysaccharid protein concentr open circuit group time higher close circuit group respect three dimension fluoresc spectroscopi gas chromatographi mass spectrometri show deposit control group contain high molecular weight compound especi long chain ester deriv phenol complex hydrocarbon wherea experiment group opposit therefor current electron chang composit cake layer high throughput sequenc indic signific higher abund electroact microorgan experiment control group two dimension correl spectroscopi show electron promot degrad polysaccharid therebi allevi membran foul
D012722;D008567
T074;T069
36,283,664
evalu role alga algal bacteri granular sludg nutrient remov microbi communiti granular characterist algal bacteri granular sludg abg bacteri granular sludg bgs control group oper day investig role alga treat synthet municip wastewat result show alga signific improv remov effici total nitrogen tn nitrogen remov load abg mg ng vssday light mg ng vssday dark higher bgs respect attribut alga enhanc nh n remov capac anaerob stage increas util effici organ denitrif alga increas relat abund denitrifi bacteria abg higher bgs moreov domin phylum alga chlorophyta chlorophyl sustain mgg vss alga signific increas content extracellular polymer substanc ep increas polysaccharid came tight bound ep studi expand understand role alga abg
D012722;D064307
T001;T032;T069;T028
36,283,663
comprehens review biolog convers lignocellulos biomass hydrogen pretreat strategi technolog advanc perspect globe depend energi generat util mani year convers ecolog concern constrain world view hydrogen altern econom develop lignocellulos biomass broad access low cost renew feedstock nonreact natur receiv lot consider global energi sourc attract altern replac fossil natur substanc energi product pretreat lignocellulos biomass essenti advanc fragment lower lignin content sustain energi generat review goal provid differ pretreat strategi enlarg solubl surfac area lignocellulos biomass biolog convers lignocellulos biomass hydrogen review oper condit enhanc method discuss review summar work condit paramet yield percentag techno econom analysi challeng futur recommend direct convers biomass hydrogen
D006859;D056804
T196;T109
36,283,662
product xylooligosaccharid camellia oleifera abel fruit shell use shell base solid acid catalyst studi aim produc xylooligosaccharid xos camellia oleifera abel fruit shell cfs use shell base solid acid deriv cfs cfs bsa cfs bsa prepar optim incomplet carbon c h follow sulfon c h yield h function group concentr mmolg cfs bsa use hydrolyz cfs ratio cfs bsa cfs c min maximum xos yield x x achiev notabl higher use subcrit h sole cfs bsa recycl reus least six time siev without substanti loss catalyt activ cfs bsa also use produc xos lignocellulos materi corncob sugarcan bagass corn stalk birchwood poplar
D028244;D031786;D015673
T047;T002
36,283,661
microalg remedi valoris pollut wastewat zero carbon circular bioeconomi overexploit natur resourc meet human need consider impact co emiss contribut global warm sever climat chang review furnish understand sourc brutal effect co emiss compel requir metamorphosi linear circular bioeconomi detail emphasi microalga type properti cultiv explain signific attain zero carbon circular bioeconomi microalg treatment varieti wastewat convers generat biomass valu ad product bio energi pharmaceut along agricultur product elabor challeng encount larg scale implement microalg technolog low carbon circular bioeconomi discuss along solut futur percept emphasi suitabl microalga wastewat treatment convers altern low carbon footprint bio energi valu ad product enforc zero carbon circular bioeconomi major focus review
D058086
T204
36,283,660
effici co product xylooligosaccharid glucos lignocellulos acidpentanol pretreat synerget role lignin remov inhibitor novel technolog co product xylooligosaccharid xos glucos monterey pine sawdust wheat straw introduc use dilut acid da pentanol pretreat effect pretreat sever ps lignin remov inhibitor byproduct concentr xos product investig optim identifi condit ps c min result maximum xos pine sawdust wheat straw due appropri lignin remov pine sawdust wheat straw format small amount inhibitor byproduct enzymat hydrolysi optim pretreat solid residu yield glucos pine sawdust wheat straw respect biomass character reveal dapentanol pretreat enhanc poros pore size along remov amorph fraction sampl therebi increas cellulos access glucos yield studi demonstr lignin remov low format inhibitor byproduct effect enhanc xos glucos product lignocellulos biomass
D008031;D000439
T123;T109
36,283,638
rhamnogalacturonan enrich pectin steam ginseng amelior lipid metabol type diabet rat via gut microbiota ampk pathway panax ginseng c meyer ginseng tradit use treat diabet polysaccharid main activ compon ginseng prove hypoglycaem hypolipidaem effect mechan remain unclear
D005894;D000069196;D003924;D003921
T007;T050;T002;T047;T001
36,283,637
bioassay guid fraction isol character hepatotherapeut di ortho galloyl quinic acid methanol extract leav pterocarpus santalinoid leaf extract pterocarpus santalinoid dc tradit use amelior age relat ailment heart liver diseas report protect toxic injuri liver
D035721
T002
36,283,636
anti depress like effect ferment gastrodia elata bl regul monoamin level bdnfnmdar pathway mice gastrodia elata blume ge chines medicin herb common use treat central nervous system relat diseas includ headach dizzi epilepsi numb limb depress
D031668
T002
36,283,635
inhibit late mrna synthesi hippocampus impair consolid reconsolid spatial memori male rat alreadi shown consolid reconsolid long term memori requir protein synthesi de novo gene transcript immedi train mnemon trace reactiv session studi also shown consolid long term memori also requir late second wave de novo gene transcript requir also occur reconsolid use two differ mrna synthesi inhibitor show blockad hippocamp late gene express restrict post train postretriev time window hinder retent long term spatial memori morri water maze task without affect function hippocampus result indic spatial memori consolid induc activ late hippocamp gene transcript machineri suggest late gene express depend reconsolid process oper dorsal hippocampus stabil reactiv mnemon trace
D065852;D000069077
T041
36,283,628
dexmedetomidin allevi pain mptp treat mice activ ampkmtornf b pathway astrocyt pain major non motor symptom contribut impair qualiti life parkinson diseas pd howev mechan treatment pain pd well studi dexmedetomidin dex use analgesia sedat deep brain stimul dbs may revers progress pd explor effect dex parkinson pain under mechan cbl mice intraperiton inject methyl phenyl tetrahydropyridin mptp mgkg establish pd model mice treat dex gkg compound c cc mgkg ampk inhibitor motor behavior test use valid pd model plantar test conduct assess mechan thermal stimul threshold immunofluoresc western blot use analyz level tyrosin hydroxylas th substantia nigra sn express c fos gfap p ampk mtor nf b tnf il dorsal horn spinal cord dhsc found mice exhibit motor dysfunct mechan allodynia thermal hyperalgesia mptp inject chang partial revers dex dex also reduc mptp induc astrocyt activ tnf il express increas p ampk reduc mtor nf b express dhsc moreov effect dex partial revers ampk inhibitor compound c conclus find reveal dex protect dopaminerg neuron pd allevi pain reduc activ dhsc astrocyt ampkmtornf b pathway therefor dex may potenti drug treat parkinson pain
D010300;D020927
T121;T047;T109
36,283,508
probabl role hyperpolar activ current dual effect cbr antagon behavior parkinson mous model recent evid genet pharmacolog anim model parkinson diseas pd suggest alter activ hyperpolar activ cyclic nucleotid gate channel hcn occur follow dopamin da deplet base data lab other endocannabinoid system ecb appear involv pd relat process therefor compar motor non motor effect intracerebroventricular icv inject cannabinoid receptor type cbr agonist win win select antagonist motor non motor symptom nms pd mous model generat icv inject hydroxydopamin ohda provid knowledg link cbr hyperpolar activ current ih conduct ex vivo investig ventral tegment area vta current studi pharmacolog antagon cbr amelior explor behavior balanc muscl strength passiv avoid memori deficit induc ohda howev anxious depress like behavior heighten also effect reduc ohda induc th level deficit ohda exposur induc sever alter spontan evok fire behavior da neuron evidenc signific increas mean number spike decreas spike half width respect interest increas amplitud sag voltag amplitud steadi state ih current seen consist effect increas ih win exacerb ohda induc action reduc spike half width increas fire frequenc addit greater amplitud sepsp elicit effect ohda sag voltag ih current amplitud fire frequenc revers administr result suggest ecb might involv ohda induc electrophysiolog alter vta da neuron anim model pd addit cbr antagonist mechan could effect modul devast effect ohda
D020734;D017557
T047;T050;T023
36,283,506
comparison ft ir whole genom sequenc identif matern toneon transmiss antibiot resist bacteria follow previous studi evalu carriag rate extend spectrum lactamas esbl produc enterobacteral esbl e carbapenem resist enterobacteral cre vancomycin resist enterococci vre methicillin resist staphylococcus aureus mrsa among pregnant women neonat current studi use first time fourier transform infrar spectrometri ft ir order determin whether antibiot resist bacteria colon neonat result vertic transmiss mother end pair matern neonat isol antibiot resist bacteria includ esbl produc e coli esbl ecoli esbl produc k pneumonia esbl k pneumonia mrsa isol subject ft ir analysi assess similar matern new born isol compar ft ir analysi result whole genom sequenc isol order defin whether ft ir spectroscopi appli bio type bacteria assess mother toneon transmiss ft ir analysi show neonat isol similar correspond matern isol belong cluster align dna sequenc matern neonat isol pair reveal ident thus confirm ft ir result conclus ft ir spectroscopi appli monitor bacteri transmiss specif matern toneon transmiss
D055624
T007
36,283,483
cobb like sirtuin oryza sativa indica regul mitochondri machineri stress condit sirtuin ubiquit natur known play import role metabol regul plant nad depend deacetylas well character studi report new member sirtuin oryza sativa indica oscobb share approx sequenc ident bacteri sirtuin class iii sirtuin member protein most present mitochondria trace amount nucleus physic interact histon h h specif deacetyl histon h lys lys posit mitochondria acetyl coa synthetas ac isocitr dehydrogenas idh target deacetyl remov acetyl group mode regul certain stress condit thus first mitochondri cobb target import plant machineri chang growth environ oscobb deacetylas activ major affect product nicotinamid adp ribos sensit certain metal ion like fe mg contrast class iii member adp ribosyl transferas activ respons abiot stress condit like dehydr low temperatur enzym also mobil nucleus regul plant metabol
D037761;D012275;D056566
T168;T126;T116;T002
36,283,482
phospholipid antioxid respons oleagin fungus cunninghamella echinulata hydrogen peroxid stress hydrogen peroxid h one major oxid stress intracellular extracellular may affect lipid membran cell membran howev mechan remain unclear present studi investig phospholipid antioxid respons cunninghamella echinulata exogen h stress integr lipidom transcriptom h signific affect phospholipid profil c echinulata expos exogen h phospholipid content reduc first day th day time lower control phosphatidyl cholin reduc signific th day lipid relat metabol map c echinulata respond h construct base transcriptom lipidom biochem analysi result show h almost mobil signal pathway cell especi ampk camp signal pathway regul metabol protein fatti acid h stress trigger high express heat shock gene antioxid enzym activ suppli nadph contribut modul intracellular redox balanc continu scaveng activ substanc thus improv myceli resist oxid stress
D006861;D020093
T121;T197;T004;T130
36,283,474
chronic toxic effect isoflucypram reproduct intestin energi metabol zebrafish danio rerio intestin vital organ involv chemic nutrient uptak biotransform intestin dysfunct impair energi materi suppli reproduct isoflucypram new succin dehydrogenas inhibitor fungicid high toxic aquat system howev chronic toxic effect isoflucypram intestin differenti aquat organ remain unknown studi zebrafish f month old expos isoflucypram day day exposur f generat adult zebrafish pair correspond f generat embryo obtain observ day exposur gut f generat zebrafish collect intestin histopatholog mitochondri morpholog analyz exposur isoflucypram result signific death hatch delay malform blood clot cluster pericardi edema microphthalmia f embryo larva exposur isoflucypram caus irregular swollen villi zebrafish gut accompani alter intestin mitochondri ultrastructur addit differenti express gene involv mitochondri energi metabol signific enrich overal data suggest chronic exposur isoflucypram associ reproduct intestin dysfunct adult zebrafish
D015027;D014874
T131;T013
36,283,451
dihydromyricetin contribut weight loss via pro brown mediat mitochondri fission white adipos dihydromyricetin dhm natur bioactiv flavonoid extract ampelopsi grossedentata common use chines herbal medicin multipl benefici pharmacolog effect includ lower blood glucos lipid well anti inflamm anti oxid hepato protect studi elucid action mitochondri dynam brown white adipos experi vivo six week old male cbl mice fed normal diet nd high fat diet hfd hfd intragastr administr dhm mgkgd experi vitro l mous primari preadipocyt induc treat various concentr dhm mous metabol phenotyp lipid accumul brown mitochondri dynam white adipocyt examin found dhm treatment reduc bodi weight fat mass improv glucos toler insulin resist cold toler mice obes dhm treatment increas express classic brown adipocyt marker ucp pgc prdm mitochondri dynam relat protein drp fis opa mfn adipos tissu likewis dhm treatment induc differenti matur l cell brown like adipocyt also enhanc express mitochondri dynam relat protein vitro moreov pro brown effect dhm abrog mitochondri fission inhibitor mdivi find indic dhm treatment induc brown remodel white adipos enhanc mitochondri fission manifest anti obes properti via pro brown mediat mitochondri fission impli may play import role prevent therapi obes relat diseas
D063154;D059305
T061;T043
36,283,412
mechanist insight alloster activ human pyruv carboxylas acetyl coa pyruv carboxylas pc catalyz two step carboxyl pyruv produc oxaloacet play key role mainten metabol homeostasi cell given involv multipl diseas pc regard potenti therapeut target obes diabet cancer albeit acetyl coa recogn alloster regul pc year under mechan acetyl coa induc pc activ remain enigmat herein use time resolv cryo electron microscopi captur snapshot pc transit state catalyt cycl structur biochem studi reveal acetyl coa stabil pc catalyt compet conform trigger cascad event includ atp hydrolysi long distanc communic two reactiv center find provid integr pictur pc catalysi unveil uniqu alloster mechan acetyl coa essenti biochem reaction kingdom life
D011766;D000103
T126;T116
36,283,410
post embryon remodel c elegan motor circuit develop anim maintain behavior output even under circuitri structur remodel hatch c elegan undergo substanti motor neuron expans synaps rewir anim continu move undulatori pattern understand circuit transit juvenil matur configur without interrupt function output reconstruct c elegan motor circuit electron microscopi across larval develop observ follow first embryon motor neuron transient interact develop post embryon motor neuron prior remodel juvenil wire second post embryon neuron initi synaps develop futur partner neurit navig juvenil nerv cord third embryon post embryon neuron sequenti build structur machineri need adult circuit embryon neuron relinquish role post embryon neuron fourth transit repeat region region along bodi anterior posterior sequenc follow birth order neuron orchestr program rewir motor circuit gradual transform asymmetr symmetr wire matur strategi support continu mainten motor pattern juvenil circuit develop adult configur
D017173;D029742
T116;T204
36,283,406
transcript function consequ alter mefc topolog organ neuron model point mutat structur variant direct disrupt code sequenc mefc associ spectrum neurodevelopment disord ndds howev impact mefc haploinsuffici neurodevelopment pathway synapt process well understood complex mechan govern regul explor function chang associ structur variant alter mefc express andor regul generat allel seri isogen human induc pluripot stem cell hipsc deriv neural stem cell glutamaterg induc neuron neuron model harbor crispr engin mutat involv direct delet mefc delet boundari point topolog associ domain tad chromatin loop encompass mefc systemat profil mutat specif alter contrast unedit control expos guid rnas edit reveal delet mefc caus differenti express gene associ neurodevelopment pathway synapt function also discov signific reduct synapt activ measur multielectrod array mea neuron cell contrast observ robust buffer mefc regulatori disrupt follow delet distal q tad loop boundari wherea homozyg loss proxim loop boundari result regul mefc express reduc electrophysiolog activ mea compar direct gene disrupt collect studi highlight consider function impact mefc delet neuron cell systemat character complex interact challeng priori predict regulatori consequ structur variant disrupt three dimension genom organ
D057026;D058953
T025
36,283,405
bi allel camsap variant caus clinic recogniz neuron migrat disord non centrosom microtubul essenti cytoskelet filament import neurit format axon transport neuron migrat requir stabil microtubul minus end target protein includ camsap famili molecul use exom sequenc sampl five unrel famili show bi allel camsap loss function variant caus clinic recogniz syndrom neuron migrat disord cardin clinic featur syndrom includ characterist craniofaci appear primari microcephali sever neurodevelopment delay cortic visual impair seizur neuroradiolog phenotyp compris high recogniz combin classic lissencephali posterior sever anterior gradient similar pafahb lis relat lissencephali sever hypoplasia absenc corpus callosum dysplasia basal ganglia hippocampus midbrain cerebellar hypodysplasia similar tubulinopathi group monogen tubulin associ disord cortic dysgenesi neural cell rosett lineag deriv affect individu display find consist phenotyp includ abnorm morpholog decreas cell prolifer neuron differenti camsap null mice display increas perinat mortal rnascop studi identifi high express level brain throughout neurogenesi facial structur consist mous human neurodevelopment craniofaci phenotyp togeth find confirm fundament role camsap neuron migrat brain develop defin bi allel variant caus clinic distinct neurodevelopment disord human mice
D054082;D009421;D054221
T019;T047
36,283,392
singl cell transcriptom inventori murin smooth muscl cell smooth muscl cell smcs execut import physiolog function numer vital organ system includ vascular gastrointestin respiratori urogenit tract smc differ morpholog function differ anatom locat molecular underpin differ remain poor understood use deep singl cell rna sequenc combin situ gene protein express analysi four murin organ heart aorta lung colon identifi molecular basi high level differ among vascular viscer airway smc well subtl differ exampl smc elast muscular arteri zonat elast arteri smc along direct blood flow arteri smc exhibit extens organotyp heterogen wherea venous smc similar across organ identifi specif smc subtyp within pulmonari vasculatur compar smc cross organ resourc offer insight smc subtyp specif function
D009131;D059467
T081;T024;T086
36,283,391
chang nuclear pore number control nuclear import stress respons mous heart nuclear pore essenti nuclear cytoplasm transport whether cell chang nuclear pore alter nuclear transport cellular function unknown show rat heart muscl cell cardiomyocyt undergo decreas nuclear pore number matur chang respons extracellular signal matur associ declin nuclear pore number associ lower nuclear import signal protein mitogen activ protein kinas mapk experiment reduct nuclear pore number decreas nuclear import signal protein result decreas express immedi earli gene mous model high blood pressur reduct nuclear pore number improv advers heart remodel reduc progress lethal heart failur decreas nuclear pore number cardiomyocyt matur result function chang demonstr termin differenti cell perman alter handl inform flux across nuclear envelop behavior
D022022;D009685
T026
36,283,390
myo filopodia support basement membran pre invas tumor boundari ductal carcinoma situ dcis pre invas stage breast cancer invas encapsul dcis basement membran bm compromis tumor cell invad surround stroma mechan regul function epitheli bms vivo poor understood myosin x myo filopodia induc protein associ metastasi poor clinic outcom invas breast cancer ibc identifi elev myo express human dcis ibc suggest link diseas progress myo promot filopodia format cell invas vitro cancer cell dissemin progress invas human dcis xenograft howev myo deplet xenograft invas lesion exhibit compromis bms poor defin border increas cancer cell dispers emt marker posit cell addit cancer spheroid depend myo filopodia generat near continu extracellular matrix boundari thus myo protect earli stage breast cancer correl tumor limit bms pro invas later stage facilit cancer cell dissemin
D002285;D001943;D018270
T191
36,283,389
pittch lysosom repair lysosom guardian cell health sustain physic damag biolog mechan chemic stressor necessit dedic mechan upkeep recent issu natur tan finkel report discoveri lysosom repair pathway control phosphoinositid oper via bulk transport lipid across er lysosom contact
D014216;D008247
T026;T121;T130;T109
36,283,388
new frontier bird migrat research bird migrat impress behavior phenomena repres complex spatiotempor strategi balanc cost live maxim fit field bird migrat research made great stride past decad yet fundament gap remain technolog spark transform studi bird migrat research reveal remark insight under behavior cognit physiolog evolutionari mechan divers journey aim encourag broad discuss promot futur studi highlight research field character major knowledg gap conflict evid name field navig social learn individu develop energet conserv approach topic summar current state knowledg provid futur outlook idea state art method advanc field integr knowledg across disciplin allow us understand adapt abil differ speci develop effect conserv strategi rapid chang world
D001717;D005075
T045;T012
36,283,387
genom adapt bird organism adapt hallmark natur select studi adapt avian system central key conceptu empir advanc field evolutionari biolog past decad leverag prolifer divers genom tool synthesi first discuss differ genom architectur avian trait relev adapt phenotyp mutat chromosom locat eg microchromosom sex chromosom specif natur eg nucleotid substitut structur variant determin may evolv shape adapt phenotyp review differ exampl avian literatur next describ sourc adapt variat whether de novo mutat exist genet variat introgress anoth speci affect evolutionari dynam trait third section review case studi genet basi key avian adapt phenotyp eg bill morpholog plumag color reveal end provid outlook identifi import challeng field focus technic aspect complet genom assembl abil valid genet associ new sourc data well discuss existenti threat pose bird habitat alter climat chang
D023281;D001717
T091;T012
36,283,386
enantiornith find bird bone deposit cretac period million year ago chanc belong enantiornithin bird extinct group bird most arbor domin terrestri environ million year ago approxim known genera account half known divers mesozo bird yet despit appar compet bird close relat live speci cretac continent environ enantiornithin mysteri went extinct end cretac alongsid non neornithin crown bird dinosaur
D005580;D025061
T014;T167
36,283,385
bird ecosystem servic bird us may find inappropri perhap distast question suggest might import valu bird lie princip way benefit peopl perhap unspoken implic enough concern befal nonetheless seem vital understand benefit enhanc human wellb common known ecosystem servic bird provid two main reason first bird high increas threat thus ecosystem servic also pressur around known bird speci late pleistocen estim becom extinct much higher percentag local popul lost serious erod around current extant bird speci consid global threaten extinct second arguabl import abil answer question bird us sens measur well understand place adequ valu broadest simpli econom sens interact peopl bird general peopl natur inde bird provid particular valuabl test understand subject long rich histori human interest studi
D017753;D001717
T070;T012;T082
36,283,384
flightless bird greater anomali natur bird fli thus spoke richard owen tower figur victorian biolog second charl darwin relat quot origin speci owen later becam strident critic darwin theori knew talk receiv bone fragment new zealand superior anatomi skill owen infer femur bird bird must incred big henc unabl fli bone arriv owen conclud belong group bird know moa stood almost twice tall among largest bird ever live figur
D005075;D001842
T045;T023;T024
36,283,383
passerin bird passeriform common known perch bird passerin speci rich group bird total near speci approxim two everi three bird speci passerin passerin global distribut among abund bird near everi terrestri locat earth owe divers abund cosmopolitan distribut passerin among familiar bird figur promin human cultur scienc exampl human long captiv beauti song mani passerin common nightingal luscinia megarhyncho europ wood thrush hylocichla mustelina north america common cultur although global discourag ecolog damag especi bird captur direct wild keep passerin pet nevertheless vocal prowess frequent abil thrive captiv made passerin import model lab base research rang neurobiolog genet contrast divers access mani passerin bird wild continu make among best anim model field base studi behavior ecolog evolut mate system life histori diseas resist ecolog evolutionari respons climat chang among mani field
D046109;D020308
T012
36,283,382
genet bird migrat bird migrat one amaz biolog phenomena exhibit organ today bird small three gram travel thousand kilomet twice year peopl familiar behaviour like recogn season movement bird year may even wit specif migratori event eg gees fli characterist v format mani peopl may know bird migrat strong genet basi especi group like songbird migrat alon night prevent juvenil follow experienc adult bird first migrat success migrat also requir coordin function mani trait behaviour trait like time orient also morpholog physiolog trait permit long distanc trek togeth trait compris call migratori syndrom primer provid broad overview research genet migratori trait earli experiment work futur function assay import bird conserv focus primarili songbird work genet migrat conduct group
D025041;D020308
T053;T012
36,283,381
collect action bird observ behaviour other cheap effect way acquir date inform environ anim chang behaviour respons acquir social inform effect propag inform forward although rule govern individu bird detect respond social cue often simpl abl produc divers rang collect action individu reap benefit includ predat avoid accur estim environ understand individu level rule favour emerg collect behaviour evolv therefor requir knowledg ecolog social context express breadth research social behaviour bird unparallel window ecolog collect behaviour provid mani opportun test whether differ speci overcom differ ecolog challeng use similar social rule whether collect behaviour bird act sensor environ
D012919;D001717
T012;T054
36,283,380
cultur bird human cultur varieti mean trend music art technolog advanc ideolog valu underpin societi mean common encompass behaviour skill idea genet determin rather learn around us share group societi human societi also exhibit term cumul cultur evolut cultur build generat learner exhibit complex effect behaviour allow us go sled high speed train count calculus speci also exhibit cultur
D003468;D009146
T068;T170
36,283,379
parent care bird parent care use imprecis catch term behavior perform breed adult benefit offspr popular research area among behavior ecologist across class ave take mani form rang warm egg incub embryo develop within eventu escap protect shell extens post hatch assist especi provid food also protect young weather predat figur primer address evolutionari forc like shape peculiar avian habit involv parent substanti post fertil invest rather one focus cost benefit complex social dynam associ elabor parent care show may regard simpl nuclear famili mom dad kid anyth simpl
D001717;D005075
T045;T012
36,283,378
bird egg spent summer studi gull appledor island gulf main east coast unit state rocki island breed coloni herring gull larus argentatus great black back gull larus marinus front row seat drama unfold bird pair laid incub egg rais chick saw chick hatch larg speckl egg figur herculean feat took hour egg chick extrem vulner mani gull offspr surviv gull soar past pilfer sandwich beach appreci hurdl overcam reach adulthood
D001717;D046091
T012
36,283,377
nest nest build bird bird nest long attract human interest beauti creation import construct import construct avian parent use protect develop egg young danger present element predat despit share protect function howev bird nest remark structur variabl built wide divers materi place manner locat exampl male australian brush turkey scrape materi larg nest mound woodpeck excav hole stork build stack sparrow swallow build cup differ materi weaver weav famous hang basket nest might built bush hole tree dangl branch sit ground might solitari hidden conspicu togeth hous hundr famili figur
D009425;D046109
T012;T054
36,283,376
mate system bird vertebr includ mammal bird sexual reproduc organ implic sexual reproduct adult bird exist male transfer sperm reproduct tract femal copul one sperm fertil egg ensu embryo develop individu male femal turn reproduc fundament featur sexual life need bring togeth male femal unit genom gamet individu sequenc interact fascin fraught conflict select act individu maxim lifetim reproduct success individu unit dna maxim number copi remain gene pool consequ bewild divers reproduct trait behaviour evolv
D012661;D012098
T081;T040;T079;T031
36,283,375
biomechan avian flight throughout record human histori bird fascin inspir human dream fli greek myth daedalus son icarus flew close sun fell death first written diodorus bce later poetic revis ovid ce evok danger hubri mani indigen peopl invok spiritu qualiti protect ascrib bird symbol freedom view sacr messeng god student bird flight leonardo da vinci first document dynam soar bird subsequ flight bird inspir human engin pursuit power aircraft design wright brother first design achiev sustain flight kitti hawk nc usa
D005426;D000401
T040;T073
36,283,374
aerodynam avian flight much awe human flight bird deriv earthbound habit bias toward emphas visual cue interpret process world although move breath air vast less dens bodi fanci imagin move limb manner would enabl us support weight air moreov air invis us unless use special tool reveal flow pattern evid visual bias contempl strong wind probabl form mental imag leav move tree branch dust swirl tornado case solid move respons forc wind rather essenc wind
D005426;D001717
T040;T012
36,283,373
ecolog evolut bird sound bird among natur social anim renown group migrat cooper forag communal roost synchron breed aggreg precis parent offspr interact coordin group defens intric territori courtship ritual context inde moment live bird capac navig complex social demand relationship tip balanc health sick reproduct success failur life death thus surpris bird evolv sophist system mediat social interact foremost among communic signal evid bird song call color pattern postur display communic signal transmit inform signal status motiv possibl futur action sensori cognit process signal receiv general signal provid benefit signal sender receiv consid bright spring plumag male wood warbler establish breed territori male plumag pattern benefit signal ownership territori help attract potenti mate preempt conflict potenti rival plumag pattern also benefit intend audienc inform femal signal potenti mate inform male degre threat might face attempt territori take communic signal essenc glue maintain cohes bird societi currenc mediat sophist relationship within
D003380;D046109
T012;T054
36,283,372
syrinx bird contribut promin terrestri soundscap earth sound aris differ sourc drum woodpeck bill clap stork feather vibrat courtship flight snipe hummingbird howev avian sound generat avian vocal organ syrinx vocal behavior use mani differ context featur promin mate choic reproduct therefor thought play import role remark diversif bird
D014828;D005075
T045;T055
36,283,371
birdsong ever felt happi lark feather nest taken someon wing watch bird help struck uncannili familiar behavior sing nest build care young name songbird oscin subord perch bird constitut rough half known avian speci note song male sometim sex group sing court mate defend territori rival birdsong contain sever mani acoust distinct syllabl typic organ stereotyp phrase span audio bandwidth exploit speech music make easi us hear appreci consequ eavesdrop human long ago detect strike parallel songbird human juvenil songbird learn sing manner similar child learn speak
D009146;D020308
T170;T012
36,283,370
spatial cognit bird find kitchen refriger middl sleepless night arriv home park lot end daili drive thing most take grant howev feat reli complex brain comput integr multipl environment intern cue togeth comput mediat process refer spatial cognit studi one activ research field modern neurosci earli john okeef record activ individu cell hippocampus freeli move rat found cell fire action potenti rat pass specif place environ examin activ pattern place cell conclud hippocampus may contain cognit map repres anim locat proxim environ sinc okeef semin discoveri half centuri ago extens research led detail character hippocamp space process rat mammalian speci
D006624;D000071037
T026;T023;T025
36,283,369
avian vision primari relianc bird vision readili frequent assert casual observ bird complet everyday behaviour suffici convinc observ bird use vision control key behaviour assert support evid bird speci relat larg portion brain devot analysi inform vision also call intellig behaviour bird seem base primarili upon visual inform thus gain inform vision use guid sophist behaviour seen vital compon make bird fascin
D001717;D014785
T040;T012;T043
36,283,368
avian brain reason primer call avian brain birdbrain even though latter term might access term birdbrain long use derog yet hope primer inspir see compliment primer take short tour first explor superfici differ bird mammal briefli mention behavior capabl bird explain bird brain neural makeup generat behavior lead briefli describ key neural circuit structur conclud ongo challeng identifi function differ neural substrat avian mammalian cognit aim short articl therefor give full review avian brain rather highlight import aspect focus comparison mammalian brain cognit
D001921;D003071
T023;T041
36,283,367
secretari bird portug describ uniqu morpholog habit secretari bird kill prey lightn quick kick head
D001717
T012
36,283,366
honeyguid clair spottiswood colleagu introduc ancient partnership wild honeyguid human honey hunter
D001717
T012
36,283,365
hawaiian songbird radiat robert fleischer colleagu introduc uniqu songbird fauna hawaii threat face
D020308
T012
36,283,364
hoatzin joel cracraft introduc hoatzin opisthocomus hoazin odd enigmat bird defi classif
D001717
T012
36,283,363
kkp yasmin foster bruce c robertson introduc enigmat critic endang kkp world flightless parrot
D056727;D010311
T098;T012
36,283,362
birdsong music emili doolittl introduc mani connect bird song human music
D009146;D020308
T170;T012
36,283,361
asian songbird crisi alexand lee pramana yuda introduc songbird trade southern eastern asia major threat region bird popul
D020308
T012
36,283,360
bird genitalia bird extern genitalia small number speci male penis either intromitt non intromitt brennan provid overview bird genitalia includ specul evolutionari forc involv
D005835;D005075
T045;T023
36,283,359
bird pollin johnson give overview bird pollin plant speci pollin
D054817;D035264
T040;T002
36,283,358
bird contributor bird special issu reminisc bird particular import
D001717
T012
36,283,355
ph sens plant ca nt mechan plant sens ph environ remain larg obscur recent studi reveal plant employ interlac bimod peptid receptor system monitor ph root apoplast readout priorit either growth defens
D010944;D010455
T121;T116;T002
36,283,354
anim behavior monkey use tool diet qualiti quantiti endur question studi human evolut tool use evolv new studi found stone tool improv diet qualiti wild capuchin monkey tool may similar increas nutrit secur ancestr hominin
D053001
T053
36,283,353
photosynthesi compat incompat pathway explain recent studi overturn long held view two distinct modif photosynthesi incompat find provid interest new insight trade off associ photosynthet metabol well like rout evolut alter one fundament process biolog
D010788
T039;T070;T044
36,283,352
mechanosens cap actin filament robust actin network adapt resist becom denser recent investig show mechanosens reli forc sensit mechan ratchet cap actin filament reorgan network mechan feedback mechan make actin base protrus amaz robust
D000199;D008841
T026;T123;T116
36,283,351
dosag compens new player x chromosom upregul dosag balanc sex chromosom autosom achiev divers mechan across vertebr invertebr new studi discov key player contribut x chromosom upregul xcu earli mous develop associ dysregul xcu human bile duct cancer pathogenesi
D004303;D014960
T026;T045
36,283,350
plant phylogenet never end cycl evolutionari gain loss zygnematophycea sister clade land plant biolog remain mysteri new studi resolv phylogeni scenario evolut multicellular clade propos
D019669
T002
36,283,349
cell biolog keep epithelium togeth neighbor divid dramat cell shape chang involv mitosi cell divis challeng integr epitheli tissu new studi reveal surpris role atyp protein kinas c keep apic contractil balanc thus prevent epitheli disrupt
D004847;D008938
T025;T043
36,283,348
human genet tale two histor jewish communiti first studi retriev genom wide data two mediev european jewish communiti england germani illustr complex interplay ancestri diseas religion cultur ethic
D007585;D012067
T078;T098
36,283,332
sum function role eye movement along mental number line arithmet western cultur small left larg right spatial numer associ constant found various simpl number process task recent suggest spatial associ also involv complex number process exampl individu make rightward upward mental movement along number line addit leftward downward movement subtract line shown particip spontan eye movement blank screen upward downward count follow associ present research investig whether eye movement along number line simpli epiphenomenon recruit spatial refer frame whether play function role arithmet comput question address use multi step problem eg show larger proport comput vs retriev compar singl step problem eg confirm pretest moreov question address addit problem vertic eye movement spatial arithmet associ found condit subtract horizont eye movement pretest main experi particip n solv addit problem follow move dot eye smooth pursuit either congruent upward incongru downward direct keep eye fixat center screen move eye freeli blank screen arithmet perform faster congruent condit upward eye movement compar condit downward eye movement central fixat free view result suggest vertic shift spatial attent along mental number line function involv addit result support view share mechan direct spatial attent extern visual represent number space implic embodi view number process discuss
D005133;D001288
T039;T041
36,283,328
toward vivo applic ag perturb angular correl ray pac spectroscopi ag perturb angular correl ray pac spectroscopi provid inform nuclear quadrupol interact therebi local structur dynam silver ion bind site brownian rotat motion ie rotat diffus ag label molecul signific affect pac spectra illustr effect simul ag pac spectra ag label molecul molecular mass span gmol reflect span fast small molecul slow larg molecul rotat diffus pac time scale simul spectra compar ag pac data obtain pilot studi involv ag bound design chelat exhibit fast reorient solut well ag label speci form ag human serum exhibit slow reorient pac time scale simul experiment data illustr typic pac signal like observ vivo follow fate ag label compound potenti vivo applic stabil studi ag radiopharmaceut dissoci studi ag label molecul follow bind anoth bio molecul bind ag label probe larger carrier protein
D002104
T131;T196
36,283,325
biomass deriv carbon nanomateri sensor applic recent year increas amount attent paid util dedic wast biomass sustain cheap abund fuel materi sourc tremend opportun maxim energi product appli differ reliabl wast biomass renew afford excel resourc result renew hydrocarbon biomass bioenergi produc green chemic manufactur carbon materi made furthermor biomass util sourc advanc carbon materi carbon materi deriv biomass also use support catalyst fuel cell polym electrolyt membran fabric electrochem sensor porous carbonac materi generat biomass high advis owe specif qualiti includ regen natur afford distinct structur sustain surfac morpholog sensor especi pore volum surfac area pore size affect electrochem catalyt activ metal nanoparticl activ dope dispers method may use improv perform sensor detect varieti target analyt biomolecul metal ion contamin food addit flavonoid key semin advanc field biomass deriv carbonac compound discuss materi composit made biomass deriv carbon depth examin evalu compar review associ technolog difficulti also discuss futur research area suggest use practic applic nano carbon materi sever integr advantag includ good electr conduct structur chemic flexibl reduc chemic function bulk product potenti make viabl candid various electrochem process come year bio carbon product wast biomass expect gain rapid scientif industri interest use electrochem devic recharg batteri emphas varieti wast biomass precursor access well recent develop manufactur bio carbon carbonac nanoparticl generat biomass shown potenti use fuel cell bioimag medicin deliveri carbon fixat catalysi gas sensor interest articl cover nanomateri new innov energi convers storag servic final remain difficulti perspect view potenti research trajectori area describ
D049329;D053768
T073
36,283,324
new hplc pattern orient approach qualiti control enter coat tablet contain aescin aesculus hippocastanum seed aesculus hippocastanum l complex mixtur triterpen saponin glycosid known aescin isol purifi character activ pharmaceut ingredi prepar drug product revers phase high perform liquid chromatograph method uv detect develop determin total triterpen glycosid enter coat tablet contain aescin pattern orient manner mobil phase consist mixtur acetonitril phosphor acid solut uv detect perform nm chromatograph column gemini c column mm mm maintain c connect precolumn c mm linear rang gml rsd intra inter day precis variat less mean recoveri rsd method show suitabl simplic rapid precis accord proven adequ qualiti control herbal drug product either registr regulartori author routin analysi
D004928;D031319
T121;T002;T109
36,283,234
effect trace pfoa microbi communiti metabol microbi select regul risk perfluorooctano acid pfoa forev chemic continu discharg mitig environ despit product use sever restrict global due transform attach adsorpt pfoa aquat environ pfoa accumul porous media sediment soil vados region howev impact trace pfoa porous media interstiti water water safeti clear work simul porous media layer use sand column explor effect g level pfoa migrat microbi communiti altern microbi function regul generat spread microbi risk day pfoa stimul proteobacteria becam domin phylum abund sinc carri antibiot resist gene arg meanwhil halogen relat dechloromona abund increas addit pfoa signific stimul protein polysaccharid product regul amino acid metabol p membran transport p acceler microbi aggreg import rapid form biofilm immobil block pfoa activ antioxid system repair damag cell membran signific regul glycerophospholipid metabol peptidoglycan biosynthesi worth note pfoa increas abund antibiot resist gene arg human bacteri pathogen hbps porous media pfoa increas proport vertic transmiss arg varg co occurr network analysi r p verifi varg main mediat hbps comprehens understand pfoa interact microecolog environ provid
D005466;D064307
T001;T032;T028;T109
36,283,233
co coagul micro nano bubbl mnbs enhanc drink water treatment studi effici mechan novel clean process mnbs micro nano bubbl wide use clean process environment treatment studi examin interact mnbs coagul studi novel process ie mnbs coagul develop enhanc drink water treatment humic acid ha remov effici use evalu effect mnbs coagul drink water treatment hydrolysi compon ratio polymer aluminum chlorid pacl without mnbs complex strength ha pacl floccul function group character use analyz mechan mnbs coagul process enhanc drink water treatment result jar test show mnbs coagul process could improv remov effici ha increas doc remov continu flow experi remov ha mnbs coagul increas remov effici uv signific chang turbid result attribut inher hydroxyl radic generat properti mnbs forc hydrolysi pacl mnbs increas al c percentag abil mnbs increas complex strength ha pacl time mnbs coagul process strong anti interfer abil almost interfer anion cation cl ca good perform natur surfac water summari mnbs coagul strong potenti practic applic enhanc effici drink water treatment
D060766;D018508
T052;T167;T057