PMID
int64 35.7M
36.4M
| Title/Abstract
stringlengths 22
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101
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stringlengths 4
64
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|---|---|---|---|
36,281,548
|
singl oper cholangioscopi guid lithotripsi ercp standard treatment common bile duct stone cbd stone hand approxim patient cbd stone complet remov stone achiev convent ercp perform endoscop sphincterotomi follow stone extract addit advanc complex procedur often necessari remov difficult bile duct stone includ endoscop papillari larg balloon dilat mechan lithotripsi advanc cholangioscopi made electrohydraul laser lithotripsi direct endoscop visual possibl ercp cholangioscopi guid lithotripsi use spyglass ds system could better treatment tool remov difficult stone focus review describ singl oper cholangioscopi manag difficult cbd stone
|
D008096;D042882
|
T061;T031
|
36,281,541
|
synthesi character dye dope au sio core shell nanoparticl super resolut fluoresc microscopi dye dope nanoparticl investig bright fluoresc probe local base super resolut microscopi nanoparticl size import super resolut microscopi get accur size object interest imag analysi due self blink behavior metal enhanc fluoresc mef ag sio au ag sio nanoparticl shown promis probe local base super resolut microscopi sever nobl metal base dye dope core shell nanoparticl investig self blink nanomateri probe observ gold silver plate nanoparticl core exhibit weak luminesc certain condit due surfac plasmon reson band produc metal gold core exhibit blink behavior enhanc blink fluoresc dye dope nanoparticl howev silver plate nanoparticl core weak luminesc exhibit blink dye dope nanoparticl exhibit behavior core fluoresc blink blink behavior stochast optic reconstruct microscopi storm super resolut analysi abl perform perform gold core nanoparticl preliminari studi use nanoparticl local base super resolut show nanoparticl suitabl use storm super resolut resolut enhanc two time better diffract limit imag core size reduc nm use hybrid au ag core
|
D053758;D053768
|
T073
|
36,281,522
|
develop japanes version depress literaci scale depress major social concern japan therefor necessari develop scale japanes assess depress literaci
|
D000067010;D003863
|
T033;T184;T169;T048
|
36,281,488
|
possibl impact nationwid vaccin outcom covid epidem north korea model studi democrat peopl republ korea north korea success suppress coronavirus diseas covid epidem via border closur howev rapid surg incid report due spread omicron variant b lead nation emerg declar may moreov lack vaccin access medic facil unclear diseas burden may exacerb despit limit epidemiolog data aim project covid transmiss north korea quantifi potenti impact nationwid vaccin compar epidemiolog outcom via scenario analysi
|
D000086382
|
T047;T067
|
36,281,487
|
multisystem inflammatori syndrom adult follow covid mrna vaccin success treatment medium dose steroid colchicin multisystem inflammatori syndrom children adult mis ca rare report complic coronavirus diseas covid potenti advers event follow covid vaccin recent case definit mis ca develop brighton collabor network howev limit number adult patient mis follow immun report still littl evid adequ treatment year old man present fever headach vomit hypotens day receiv second covid vaccin pfizer biontech vaccin accord brighton collabor case definit patient met definit case mis vaccin level diagnost certainti administr medium dose prednisolon mgd colchicin mgd symptom sign improv rapid dose prednisolon gradual taper third week patient confirm full recoveri without medic week first report show low dose steroid combin colchicin may effect treatment option mis vaccin
|
D000086382
|
T047;T067
|
36,281,486
|
matern neonat outcom pregnant women coronavirus diseas korea studi aim describ matern obstetr neonat outcom pregnant women coronavirus diseas covid identifi predictor associ sever covid
|
D000086382;D011251;D047928
|
T047;T046;T067
|
36,281,485
|
outcom patient lung transplant waitlist korea korean network organ share data analysi demand lung transplant continu increas korea donor shortag waitlist mortal critic issu studi aim evalu factor affect waitlist outcom time registr lung transplant korea
|
D016040;D001789
|
T061;T129;T185
|
36,281,484
|
degrad multifunct porphyrin base porous organ polym nanosonosensit tumor specif sonodynam chemo immunotherapi sonodynam therapi sdt benefit intrins merit noninvas deep tissu penetr receiv increas consider attent reactiv oxygen speci ros base tumor treatment howev current sonosensit usual suffer low tumor lesion accumul insuffici ros generat effici ultrasound non biodegrad serious imped therapeut outcom addit difficult sdt alon complet erad tumor complex immunosuppress tumor microenviron tme herein simultan employ sonosensit porphyrin build block glutathion gsh respons disulfid bond construct novel degrad multifunct porphyrin base hollow porous organ polym pop nanosonosensit h pys ha mr combin sdt demand chemotherapi immunotherapi take uniqu advantag pop design structur high specif surfac area h pys ha mr nanosonosensit achiev tumor target accumul gsh trigger drug releas low frequenc ultrasound activ ros generat encourag result furthermor multifunct nanosonosensit effect evok immunogen cell death icd respons combin sdt chemotherapi primari distal tumor growth suppress meanwhil h pys ha mr exhibit favor biodegrad biosafeti therefor studi provid new strategi reason design construct pop relat sonosensit combin sdtchemotherapyimmunotherapi tripl treatment modal erad malign tumor
|
D011166;D014464;D009369;D053758
|
T061;T123;T073;T109;T191
|
36,281,465
|
vitro vivo neuroprotect effect sarcosin alzheim diseas ad neurodegen disord character behavior psycholog symptom addit cognit impair loss memori exact pathogenesi genet background ad unclear remain effect treatment option sarcosin n methyl deriv glycin show promis therapeut strategi cognit disord knowledg impact sarcosin supplement ad yet elucid therefor aim determin neuroprotect potenti sarcosin vitro vivo ad model vitro studi demonstr sarcosin increas percentag viabl cell aluminum induc neurotox alcl induc rat model ad level antioxid capac signific decreas express level app bace tnf apha psenen gene elev compar control group addit histopatholog examin hippocampus alcl induc rat brain show presenc neurofibrillari tangl nfts howev administr sarcosin produc mark improv protect ad associ patholog induc alcl experiment rat therefor investig may contribut design novel therapeut strategi use sarcosin manag ad patholog
|
D018696;D000544
|
T121;T047;T169;T048
|
36,281,464
|
determin virul factor resist profil methicillin resist staphylococcus aureus strain among differ type spa agr scc mec order restrict spread methicillin resist aureus mrsa hospit necessari character isol rapid precis object studi determin virul factor resist profil mrsa strain among spa agr scc mec type total mrsa isol collect clinic specimen mrsa isol character antimicrobi suscept test virul gene agr type spa type scc mec type accord find mrsa strain resist cefoxitin resist erythromycin clindamycin respect type ii agr predomin frequenc among differ spa type type frequent mrsa isol scc mec type iii pvl tst gene found mrsa isol respect among mrsa strain erma ermb ermc present case respect addit mrsa strain harbor aminoglycosid resist gene result studi reveal mrsa rate region dramat high better infect control guidelin hospit well ongo epidemiolog surveil studi could strong suggest effect prevent spread mrsa inpati
|
D055624;D013203
|
T047;T007
|
36,281,463
|
diagnost valu neutrophil lymphocyt ratio effect biomark eye disord meta analysi neutrophil lymphocyt ratio nlr reflect dynam relationship innat neutrophil adapt lymphocyt cellular immun respons systemat review meta analysi conduct critic evalu literatur regard use nlr reliabl mean detect sever ocular disord studi regist prospero id crd three databas includ pubm embas scopus web scienc search septemb restrict articl languag final articl recogn elig meta analysi found patient eye diseas signific elev level nlr comparison healthi control smd ci p subgroup analysi patient keratoconus smd ci p glaucoma smd ci p pterygium smd ci p idiopath epiretin membran smd ci p higher level nlr compar healthi control howev nlr level patient dri eye diseas similar healthi control smd ci p said nlr valuabl marker system inflamm signific increas mani eye disord suggest inflamm play key role pathophysiolog diseas
|
D009504;D005128
|
T047;T025
|
36,281,462
|
identif valid dna damag repair relat signatur diffus larg b cell lymphoma diffus larg b cell lymphoma dlbcl common subtyp non hodgkin lymphoma adult whose prognost score system remain improv dysfunct dna repair gene close associ develop prognosi diffus larg b cell lymphoma aim studi establish valid dna repair relat gene signatur associ prognosi dlbcl investig clinic predict valu signatur
|
D016403
|
T191
|
36,281,461
|
compar studi asymptomat malaria forest rural deplet forest urban set low malaria transmiss covid pandem period global malaria morbid mortal wit increas part due disrupt control program activ impos covid pandem therefor still signific burden malaria cameroon need attent front attain elimin goal normal expect typic forest ecolog undergon urban subject high rate ecolog instabl also shift characterist perenni malaria transmiss shift type malaria endem plagu distort forest ecolog observ compar studi random enrol particip rural urban set forest zone low malaria transmiss period coincid onset covid pandem optim structur questionnair employ collect socio demograph data associ risk factor carestart malaria hrp antigen test perform particip set determin preval communiti asymptomat malaria particip rural urban communiti overal preval asymptomat malaria detect plasmodium falciparum antigen particip urban communiti preval posit rural communiti posit simpl logist regress model rural forest communiti farm around hous statist signific predictor test posit coeffici ci p valu coeffici ci p valu respect multivari model strongest predictor test posit live rural communiti p odd ratio ci result indic low transmiss period preval asymptomat malaria differ deplet urban rural forest set suggest need strateg target intervent control asymptomat malaria
|
D000086382;D008288;D016778
|
T047;T067
|
36,281,460
|
hpv express loss cell differenti primari bladder tumor primari bladder tumor high degre malign investig express human papillomavirus type hpv primari bladder tumor loss cell differenti explor signific hpv detect expect diseas treatment provid theoret basi
|
D030361;D001749
|
T047;T191
|
36,281,422
|
autolog bioactiv compound concentr growth factor amelior fistula heal anal fistula pig model promot prolifer migrat human skin fibroblast via regul mekerk pathway recent evid suggest autolog concentr growth factor cgf new bioactiv compound autolog blood use wide ingeni biomateri tissu regener anti inflammatori properti studi investig whether cgf could involv treatment fistula heal anal fistula purpos porcin anal fistula model conduct use rubber band ligat method collect pig autogen cgf treat fistula cgf treatment promot fistula heal reflect downregul inflammatori factor upregul growth factor promot epitheli mesenchym transit increas collagen synthesi besid rrna gene sequenc analysi fistula tissu control cgf group show microbi popul exhibit signific differ vadinca blastomona deinococcus devosia sphingomona rubrobacteria gw cgf volunt collect process small interf rna sirna erk sirna negat control transfect human skin fibroblast hsf result show cgf also promot prolifer extracellular matrix relat function hsf well activ mekerk pathway vitro vivo final knockdown erk revers effect cgf promot wound heal hsf collect result suggest cgf bioactiv compound autolog blood exhibit great potenti repair fistula well promot prolifer migrat human skin fibroblast trigger mekerk signal find provid fresh perspect understand role cgf manag fistula
|
D020935;D012003
|
T190;T020;T044
|
36,281,357
|
definit novel cuproptosi relev lncrna signatur uncov distinct surviv genom alter treatment implic lung adenocarcinoma cuproptosi newli discov copper independ cell death modal limit evid suggest critic implic human cancer nonetheless clinic impact cuproptosi relev lncrnas lung adenocarcinoma luad remain larg ill defin present studi aim defin cuproptosi relev lncrna signatur luad discuss clinic util
|
D062085;D008175;D000230
|
T123;T191;T114
|
36,281,286
|
cost effect cardiovert defibril implant kazakhstan cardiovascular diseas lead caus morbid mortal worldwid implement effect technolog implant cardiovert defibril icd patient risk sudden cardiac death requir addit health system resourc
|
D016757;D017147
|
T046;T074
|
36,281,234
|
use network pharmacolog anim experi investig therapeut mechan polydatin vincristin induc neuropath pain polydatin pd primari activ compound polygonum cuspidatum sieb demonstr exert anti inflammatori neuroprotect activ present studi aim explor therapeut mechan pd chemotherapi induc neuropath pain
|
D032761;D009437;D004365;D000970
|
T184;T121;T123;T109;T062;T047
|
36,281,228
|
relationship bmi lung function popul differ characterist cross section studi base enjoy breath program china analyz relationship bodi mass index bmi lung function may help optim screen manag process chronic obstruct pulmonari diseas copd earli stage
|
D050177;D029424
|
T033;T047
|
36,281,227
|
guidanc valu procalcitonin detect select switch point sequenti therapi patient acut exacerb chronic obstruct pulmonari diseas complic respiratori failur analys guid valu procalcitonin pct select ventil switch point sequenti mechan ventil patient acut exacerb chronic obstruct pulmonari diseas copd respiratori failur provid refer optimis mechan ventil patient copd respiratori failur
|
D029424;D012131
|
T047;T046
|
36,281,210
|
inhal nitric oxid acut sever pulmonari hypertens sever acut respiratori distress syndrom secondari covid pneumonia case report background inhal nitric oxid ino use treatment pulmonari arteri hypertens pah sever hypoxia hypox vasoconstrict caus sever acut respiratori distress syndrom ard induc pulmonari hypertens hemodynam implic main secondari right ventricl rv systol function impair report case use ino critic ill patient bilater sar cov pneumonia sever ard hypoxemia lead acut sever pah caus ventilationperfus mismatch rv pressur overload rv systol dysfunct case report year old woman admit intens care unit sever ard associ sar cov pneumonia requir invas mechan ventil sever hypoxia hypox vasoconstrict develop lead acut increas pulmonari vascular resist sever moder tricuspid regurgit rv pressur overload rv systol function impair rv dilat follow h treatment ino ppm signific oxygen hemodynam improv note allow vasopressor stop h ino treatment echocardiographi show mild tricuspid regurgit non dilat rv impair transvers free wall contractil paradox septal motion ino maintain day dose ino progress decreas advers effect maintain improv oxygen hemodynam status allow respiratori wean conclus sustain acut hypoxia ard secondari sar cov pneumonia lead pah caus ventilationperfus mismatch rv systol impair ino consid patient signific pah caus hypoxemia rv dysfunct
|
D006976;D000086382;D014262;D012128
|
T047;T046;T067
|
36,281,208
|
review biolog mechan dexmedetomidin postop neurocognit disord postop neurocognit disord common neurolog complic follow surgeri general character vari degre cognit impair postop neurocognit disord exhibit short term postop delirium andor long term postop cognit dysfunct addit postop neurocognit disord may result poor outcom patient lead caus postop morbid mortal particular elder patient recent heighten interest mechan clinic treatment postop neurocognit disord though influenc factor mechan postop neurocognit disord reveal remain troublesom problem clinic depart dexmedetomidin common use anesthet adjuv may help improv postop cognit impair especi condit postop acut event postop delirium within week oper delay neurocognit recoveri postop cognit dysfunct day recent literatur dexmedetomidin shown exert posit effect cognit impair clinic anim studi especi postop neurocognit disord howev clinic find support efficaci though mechan dexmedetomidin postop neurocognit disord propos signal pathway associ inflamm apoptosi evid fragmentari disput literatur therefor articl aim review potenti biolog mechan under dexmedetomidin effect postop neurocognit disord provid refer futur studi
|
D020927;D019965;D000079690
|
T121;T048;T109
|
36,281,207
|
risk factor polyomavirus cytomegalovirus viruria co infect follow renal transplant patient background interact viral infect may associ increas morbid renal transplant studi aim identifi incid risk factor viruria infect renal transplant recipi materi method longitudin studi episod record kidney transplant patient hospit vietnam includ bk jc polyomavirus cmv ebv hsv detect multivari cox regress analysi perform evalu risk factor viruria infect result fifti six patient viruria co infect incid jc cmv bk infect common viruria respect cox regress reveal risk factor jc singl infect dose mmf hr corticoid hr hypertens hr hematuria hr risk factor cmv infect male sex hr egfr hr risk factor bk singl infect hypertens hr proteinuria hr higher tacrolimus trough level hr dose mmf hr hypertens hr fast plasma glucos hr proteinuria hr tacrolimus trough level hr dose mmf hr independ risk factor viruria co infect conclus kidney function associ incid viruria higher tacrolimus trough level dose mmf associ higher risk bk jc co infect
|
D016030;D001739;D011120;D027601;D060085;D007674;D003586;D006973
|
T061;T005;T047
|
36,281,202
|
presenc hypertens pregnanc determin futur risk metabol syndrom observ studi studi aim examin preval time interv metabol syndrom ms develop among women hypertens disord pregnanc hdp compar women normal deliveri data deliveri nation health insur system databas korea use compar women diagnos hdp normal singleton pregnanc use custom databas conduct longitudin analysi ms develop ms observ patient normal deliveri group hdp group p time ms develop hdp group signific shorter normal deliveri group vs year p hdp group signific increas risk odd ratio confid interv ci develop ms elev systol blood pressur strong contribut increas risk develop ms ci hdp increas risk ms develop later life ms develop exhibit shorter time period women hdp women hdp undergo intens assess ms compon
|
D046110;D024821;D011225
|
T047;T046
|
36,281,201
|
opioid prescrib practic trauma patient discharg exploratori retrospect chart analysi studi examin opioid prescrib pattern discharg trauma center major canadian hospit compar guidelin provid illinoi surgic qualiti improv collabor isqic framework recogn associ reduc risk retrospect chart review patient data trauma registri januari octob total discharg chart nave opioid patient includ analysi morphin milligram equival per day mmeday comput patient prescrib opioid compar standard practic guidelin patient prescrib opioid male femal prescrib opioid patient year old best practic guidelin follow case patient prescrib mg mmeday major prescrib opioid day prescrib extend releas opioid none strong like fentanyl patient receiv multimod approach altern opioid case plan opioid discontinu howev receiv acut pain servic referr major prescript provid adher best practic guidelin outlin isqic framework result encourag respect feasibl implement opioid prescript guidelin effect howev routin monitor necessari ensur adher maintain
|
D000701;D010351
|
T121;T058;T131;T109
|
36,281,200
|
updat systemat review associ tlr polymorph rs cancer risk toll like receptor tlr lipopolysaccharid receptor may influenc tumor progress inflammatori respons immun respons complex process main occur within cell correl tlr neoplasm great interest discrep remain
|
D013274;D051197
|
T191;T116;T192
|
36,281,199
|
determin preval locat musculoskelet pain elit para athlet tendenc musculoskelet complaint injuri trauma remain signific among para athlet aim studi identifi verifi variabl impact incid locat musculoskelet pain elit athlet disabl assum type disabl type sport type injuri trauma crucial determin preval locat musculoskelet pain para athlet direct participatori observ method use studi includ subject survey questionnair object anthropometr method assess studi includ male femal elit para athlet polish nation team sit volleybal sg n para swim sg group para athlet most report pain neck lower back spearman rank order correl show sever larg invers proport relationship somat paramet valu nordic musculoskelet questionnair last day nmq sg moder larg correl bodi adipos index bai preval injuri total number rehabilit session number humer joint finger rehabilit session break train week sg group relationship found durat paralymp train number injuri rehabilit session r p exclus train less week r p age para athlet correl nmq wrist r p durat disabl type sever disabl may crucial determin preval locat pain musculoskelet system para athlet sport specif train seem induc specif musculoskelet complaint
|
D000080050;D059352;D013177;D001265
|
T033;T056;T098;T037
|
36,281,198
|
tran cathet closur asd abnorm connect left pulmonari vein vertic vein case report partial anomal pulmonari venous connect rare congenit anomali one pulmonari vein connect venous circul lead left right heart shunt although correct anomal pulmonari venous connect achiev surgeri rare instanc abnorm pulmonari vein dual connect left atrium major system vein circumst cathet base treatment might becom feasibl option
|
D011667;D006344;D012587
|
T019;T023;T047
|
36,281,197
|
studi relationship incid measl nosocomi exposur measl epidem season chongq measl vaccin supplementari immun epidemiolog characterist measl chang chongq china addit accord data nation measl surveil inform system proport measl case histori hospit visit day prior onset measl increas year year studi necessari elimin influenc nosocomi exposur measl perform case control studi seven district chongq june august identifi risk factor measl virus infect suscept laboratori confirm measl younger year old match one control age resid interview case patient control regard potenti risk factor measl virus infect suscept unadjust adjust match odd ratio confid interv cis calcul use non condit logist regress cross section analysi behavior characterist visit hospit case control group found differ two group choic hospit visit first time p nosocomi transmiss risk tend develop outpati servic respiratori medicin analysi use one way anova relationship hospit visit prior onset incid risk measl visit hospit five time within week prior onset affect incid ci relationship number type hospit visit prior onset risk nosocomi exposur measl show visit communiti hospit children hospit general hospit risk visit two hospit affect incid ci base analysi relationship number hospit visit onset risk nosocomi exposur measl chanc visit hospit increas onset risk nosocomi exposur measl infect high pediatr hospit nosocomi exposur risk factor consid control measl
|
D003428;D008457
|
T047
|
36,281,196
|
sever gastrointestin injuri associ sar cov infect thrombosi inflamm retrospect case seri studi acut gastrointestin injuri agi associ sever acut respiratori syndrom coronavirus sar cov infect low incid complic patient admit intens care unit icu pathophysiolog knowledg relat agi limit studi publish topic therefor studi carri identifi clinic histopatholog featur patient sar cov infect grade iv agi
|
D000086382;D013927;D000007
|
T047;T046;T067;T037
|
36,281,195
|
race emerg depart manag febril seizur determin racial dispar exist manag febril seizur larg pediatr emerg depart ed perform retrospect cross section analysi children month year old present ed febril seizur year period multivari logist regress model built examin associ race primari outcom neuroimag secondari outcom hospit admiss abort anticonvuls prescript ed discharg ed visit studi period overal children underw neuroimag admit children discharg ed prescrib abort anticonvuls differ race neuroimag hospit admiss howev black children less like prescrib abort anticonvuls adjust odd ratio aor confid interv ci compar non black peer adjust demograph clinic confound stratif insur reveal dispar exist medicaid insur patient aor ci privat insur patient found racial dispar neuroimag hospit admiss among ed patient febril seizur find racial dispar secondari outcom abort anticonvuls prescript driven primarili individu medicaid insur pattern find may reflect lack standard recommend regard anticonvuls prescript contrast guidelin issu ed manag decis investig potenti treatment guidelin reduc racial dispar need
|
D003294
|
T047
|
36,281,194
|
mine tcga geo databas predict poor prognosi lung adenocarcinoma base regul express tns investig clinic signific tensin tns human cancer particular lung cancer mine cancer genom atlas databas lung adenocarcinoma tcga luad gene express omnibus databas predict poor prognosi base regul express tns luad correl clinic patholog featur patient tns gene express analyz use wilcoxon sign rank test cox regress analysi use evalu associ clinicopatholog characterist overal surviv os cancer patient use tcga data relationship tns express cancer patient surviv evalu kaplan meier surviv curv meta analys go kegg also includ data mine method express level tns luad tissu higher adjac normal tissu p accord kaplan meier surviv curv luad patient high tns express wors prognosi low tns express p os p progress free surviv posit correl tns express poor os found univari multivari analys increas tns express luad close correl higher diseas stage p posit lymph node p larger tumor size p moreov meta analysi includ seven independ dataset show luad patient higher tns poorer os combin hazard ratio confid interv high tns popul regul actin cytoskeleton extracellular matrix receptor interact focal adhes differenti enrich integrin laminin gene also associ tns tns express may potenti biomark predict poor surviv luad moreov correl tns integrin may attribut role tns luad
|
D000077192;D008175
|
T191
|
36,281,193
|
predict hospit mortal mimic iii patient nomogram combin sofa score predict mortal patient provid refer doctor judg physic condit studi aim construct nomogram improv predict accuraci patient mortal patient sever diseas screen medic inform mart intens care mimic iii databas patient random select train set model establish use test set least absolut shrinkag select oper lasso regress method use filter variabl select predictor multivari logist regress fit use determin associ hospit mortal risk factor construct nomogram total patient includ area curv auc clinic nomogram base risk factor select lasso multivari logist regress confid interv ci ci train test set respect therefor nomogram might help predict hospit mortal patient admit intens care unit icu
|
D049451;D063305
|
T081;T033;T170
|
36,281,192
|
continu glycemia monitor periop period patient undergo total knee hip arthroplasti protocol prospect observ studi everi surgic subspecialti surgic site infect ssi implant infect although occur seldom pose threat patient health risk factor state diabet mellitus dm consid one widespread health relat problem st centuri orthopedist perform big joint replac usual concern older adult therefor often deal patient suffer comorbid dm frequent one furthermor often remain underdiagnos risk complic rapid begin rehabilit start day follow surgeri elimin debilit impact dm hypoglycemia surgic patient aim investig relationship glycemia valu postop outcom certain period time patient undergo orthoped surgeri particip meet inclus criteria insert glycemia measur devic dexcom g inc san diego ca period time first time take place day prior surgeri right surgeri second time period anoth day patient undergo standard total knee arthroplasti total hip arthroplasti procedur patient assess preoper day month postop assess joint condit consist patient report outcom knee injuri osteoarthr outcom score harri hip score western ontario mcmaster univers osteoarthr index womac assess potenti ssi cardiovascular complic finnish diabet risk score findrisc systemat coronari risk evalu score clinic examin investig influenc orthoped surgeri anesthesia glycemia signific safeti earli patient mobil big joint surgeri investig chang glycemia patient normal glycemia metabol potenti protect hypoglycemia hospit stay increas awar potenti develop dm futur addit studi correl periop glycem level risk cardiovascular event one year follow influenc ssi implant complic
|
D019644;D019645;D007003;D010003
|
T061;T047
|
36,281,191
|
eptifibatid induc acut profound thrombocytopenia case report eptifibatid antiplatelet agent use medic manag acut coronari syndrom although multipl studi reveal signific associ eptifibatid develop thrombocytopenia recent case report brought attent relat rare side effect
|
D054058;D013921
|
T047
|
36,281,190
|
relationship hour urinari sodium potassium mental health migrain patient cross section studi lack evid consensus term associ dietari intak sodium na potassium k mental health use hour urinari sampl gold standard method conduct studi explor associ dietari intak na k paramet mental health includ depress anxieti stress among iranian popul diagnos migrain present studi subject year old confirm diagnosi migrain enrol mental health investig depress anxieti stress scale dass questionnair dietari intak na k estim mean hour urin sampl multinomi logist regress analysi implement odd ratio confid interv ci state control potenti confound hour urinari na associ signific risk depress ci p adjust confound highest tertil hour urinari nak ratio lower odd depress ci p margin signific lower risk anxieti ci p stress ci p conclus higher hour urin na associ signific lower risk depress moreov hour nak ratio signific associ lower risk depress anxieti stress
|
D012982;D008881
|
T168;T047
|
36,281,189
|
prognost valu lymph node ratio cervic cancer meta analysi role lymph node ratio lnr exist tumor node metastasi classif system verifi one prognosi predict factor work evalu lnr perform predict cervic cancer cc prognosi meta analysi
|
D008198;D002583
|
T023;T191
|
36,281,188
|
mathemat model intraop predict metastasi region lymph node patient clinic stage non small cell lung cancer remain challeng determin region metastasi lymph node oper clinic stage non small cell lung cancer nsclc studi aim establish intraop mathemat model nomogram predict hilar intrapulmonari node metastasi hnm mediastin node metastasi mnm patient clinic stage nsclc clinicopatholog variabl patient deriv cohort underw thoracoscop lobectomi complet lymph node dissect retrospect analyz associ hnm mnm analyz variabl develop multivari logist model nomogram estim risk lymph node metastasi differ region predict efficaci valid valid cohort patient confirm carcinoembryon antigen ngml cyfra ngml maximum diamet tumor cm tumor differenti grade iii bronchial mucosa cartilag invas vascular invas predictor hnm carcinoembryon antigen ngml cyfra ngml maximum diamet tumor cm tumor differenti grade iii bronchial mucosa cartilag invas vascular invas viscer pleural invas predictor mnm valid predict model base result demonstr good discriminatori power predict model help decis make process specif therapeut strategi region lymph node metastasi patient clinic stage nsclc
|
D002289;D008175
|
T191
|
36,281,187
|
health educ action male breast cancer protocol systemat review meta analysi although rare rate diagnosi male breast cancer mbc increas year quit aggress male organ strategi health educ dissemin knowledg mbc essenti earli discoveri find better prognosi
|
D018567
|
T191
|
36,281,186
|
associ conscienti team emot intellig moder mediat model investig influenc interperson emot regul conscienti team emot intellig total colleg student investig conscienti subscal big five person questionnair team emot intellig scale leadership posit emot oper questionnair varianc analysi pearson product differ correl analysi multipl regress analysi path analysi use order avoid possibl skew problem bootstrap method use calcul structur equat model spss amo r softwar use statist analysi total questionnair sent effect questionnair recov total score colleg student team emot intellig interperson understand ask feedback emot manag organiz cognit relationship build problem solv abil respect conscienti signific predict team emot intellig leadership posit emot oper furthermor conscienti could predict team emot intellig mediat individu emot intellig interperson posit emot regul play part mediat role conscienti team emot intellig
|
D056348;D010551;D007398
|
T054;T055;T041;T080
|
36,281,185
|
identif prognost gene earli basal like breast cancer weight gene co express network analysi breast cancer bc becom lead caus death women malign increas threaten health women worldwid howev lack effect target drug basal like bc therefor biomark relat prognosi earli bc need identifi
|
D001943
|
T191
|
36,281,184
|
diagnost perform dual energi comput tomographi hcc transarteri chemoembol util virtual unenhanc low kev virtual monochromat imag purpos studi evalu use virtual unenhanc vue low kev virtual monochromat imag vmi diagnos viabl hepatocellular carcinoma hcc transarteri chemoembol tace retrospect studi includ patient suspect viabl hcc tace underw multiphas liver comput tomographi includ true unenhanc tue phase convent cv enhanc phase dual energi scanner vue imag kev kev vmis enhanc phase reconstruct use dual energi comput tomographi data everi patient six combin imag set tue cv tue tue vue cv vue vue evalu two reader compar refer standardther statist signific differ p sensit specif among imag combin combin interobserv agreement almost perfect diagnost odd ratio show higher trend combin convent imag current regard diagnost perform liver comput tomographi includ tue cv enhanc phase recommend tumor surveil tace vue vmis distinct advantag compar convent imag
|
D006528;D008113;D016461
|
T061;T191
|
36,281,183
|
manag treatment ankl sprain accord clinic practic guidelin prisma systemat review later sprain ankl frequent injuri popul general appear emerg servic frequent general object review current clinic practic guidelin cpgs manag treatment ankl sprain assess qualiti analyz level evid summar grade recommend
|
D016512;D013180
|
T037
|
36,281,182
|
meta analysi prognost valu circul tumor cell gastrointestin cancer detect circul tumor cell ctcs becom new strategi predict prognosi cancer patient howev limit systemat research evid avail detect ctcs various gastrointestin tumor esophag cancer ec colorect cancer crc gastric cancer gc topic address assess prognost signific ctcs gastrointestin tumor
|
D009360;D004938;D013274
|
T191;T025
|
36,281,181
|
longitudin evalu year chang anxieti depress risk factor among parent childhood adolesc patient resect osteosarcoma cohort studi psycholog disord often occur among parent children cancer current studi aim explor longitudin chang anxieti depress relat factor among parent childhood adolesc patient osteosarcoma total childhood adolesc patient osteosarcoma underw tumor resect correspond parent enrol hospit anxieti depress scale anxieti had had depress had parent evalu baselin day patient hospit discharg year year year year baselin rd year had p had score p anxieti rate p depress rate p elev meanwhil anxieti sever p depress sever p also increas furthermor multivari logist regress analysi present role mother divorcedwidow marit status declin famili annual incom elev ennek stage amput independ correl elev risk parent baselin anxieti depress p addit declin famili annual incom elev ennek stage amput independ correl increas risk parent year anxieti depress p anxieti depress deterior time parent childhood adolesc patient osteosarcoma affect parent role marit status famili annual incom surgeri type ennek stage
|
D003863;D012516
|
T184;T191;T048
|
36,281,180
|
epidemiolog risk factor notifi clostridium botulinum infect taiwan botulinum toxin produc clostridium botulinum gram posit anaerob bacterium studi aim examin epidemiolog characterist includ sex age season infect occur place resid epidemiolog trend confirm botul case taiwan studi examin annual summari data report botul taiwan center diseas control avail public internet found confirm domest case botul incid botul rang per peak year investig period year interv use studi result show decreas trend case term patient gender age place resid patient femal age year resid taipei northern taiwan number botul case taiwan compar year found signific differ among patient within age group year p odd ratio confid interv signific differ among patient whose place resid taipei metropolitan area p odd ratio confid interv case botul among age year last year botul children show increas trend total children found botul children male infect spring summer studi first report number confirm domest case botul surveil data taiwan center diseas control studi also found place resid age associ increas risk botul taiwan inform may use policymak clinic expert direct prevent control base activ regard botul result sever ill greatest burden taiwanes
|
D001906;D001905
|
T121;T116;T131;T037;T047
|
36,281,179
|
clomiphen citrat mild stimul improv follicular develop outcom pcos women high lutein hormon poor ovarian respons case report polycyst ovari syndrom pcos main caus anovulatori infertil women reproduct age patient pcos high serum basal lutein hormon lh level almost pcos women high lh poor ovarian respons por report case pcos woman high basal lh level cancel due por two consecut control ovarian stimul treatment consid relat suppress lh level downregul clomiphen citrat cc combin human menopaus urinari gonadotropin hmg mild regimen affect lh level obtain good follicular develop provid new treatment insight patient pcos combin por
|
D011085
|
T047
|
36,281,178
|
surgic oper combin bronchoscopi treatment fungal empyema case report fungal empyema chronic refractori diseas difficult control thorac infect face problem recurr control infect reduc probabl recurr difficult problem surgic oper combin endobronchi therapi use control infect seal fistula elimin residu caviti achiev good result
|
D004653;D005402;D016724;D001983
|
T047;T190
|
36,281,177
|
diagnosi acinetobact pittii patient china multiplex pcr base target gene sequenc platform cerebrospin fluid case report literatur review tradit diagnosi model great challeng etiolog diagnosi central nervous system cns diseas similar clinic manifest especi diagnosi rare pathogen import make rapid accur identif pathogen guid clinic choic administ countermeasur
|
D060885;D002442
|
T063;T121;T195;T109
|
36,281,176
|
refractori behet diseas treat low dose interleukin case report behet diseas bd autoimmun diseas present recurr oral aphthous ulcer genit ulcer uveiti skin lesion cutan manifest often refractori resist convent therapi report provid new treatment low dose interleukin il refractori bd patient
|
D001528;D004893;D019226
|
T047
|
36,281,175
|
downward referr experi stroke caregiv region medic allianc china phenomenolog studi downward referr platform region medic allianc provid possibl follow rehabilit transit care increas stroke survivor also contribut ration use resourc health promot stroke survivor howev downward referr rate low compar upward referr present scholar explor downward referr experi medic demand perspect qualit studi experi may also truli reflect influenc factor unwilling downward referr therefor studi explor subject experi stroke caregiv experienc downward referr stroke attack often lead lack autonomi patient make difficult complet interview descript phenomenolog studi adopt purpos sampl strategi use recruit stroke caregiv interview guid semi structur interview guid encourag interviewe reflect experi downward referr coliazzi data analysi process appli analysi data reveal theme cope challeng disrupt inform gap medic nurs transit potenti enabl factor result studi show lack knowledg medic allianc non share medic inform non homogen medic qualiti identifi imped posit attitud toward downward referr factor bad experi cours interviewe posit experi smooth referr comfort environ may potenti enabl factor attitud toward downward referr challeng need medic demand downward referr worthi attent solv correspond measur improv downward referr rate referr experi
|
D020521;D000071939
|
T061;T047
|
36,281,174
|
near infrar fluoresc guid laparoscop cholecystectomi spectrum complic gallston diseas icg fluoresc icgf guidanc laparoscop cholecystectomi lc gain wider accept accru data larg address icgf guidanc lc patient uncompl gallston diseas ug acut cholecyst pauciti data relat complic gall stone diseas cgs choledocholithiasi bilio enter fistula remnant gall bladder etc purpos studi evalu role icgf lc spectrum cgs state art chip camera system retrospect review prospect maintain databas patient underw icgf guid lc period june st till decemb th form part studi clinic profil find icgf lc cgs studi data studi evalu potenti role icgf lc cgs patient male femal among uncompl complic gallston diseas group respect icgf show cbd visual cystic duct icgf guidanc help manag cgs prior complet lc novel applic patient undergo cbd explor small seri patient cgs icgf guidanc enabl lc laparoscop subtot cholecystectomi patient respect studi highlight potenti role advantag icgf guid laparoscop manag cbd stone bilioenter fistula complet cholecystectomi cystic duct stone larg scale multicent prospect studi requir clarifi role icgf wide spectrum cgs
|
D017081;D042882;D042883
|
T061;T047;T031
|
36,281,173
|
adapt intern dysphagia diet standardis initi east asia feasibl studi dysphagia food water deliv safe oral caviti stomach treat use textur modifi food thicken fluid countri diet modif textur measur standard intern dysphagia diet standardis initi iddsi develop sever countri owe cultur differ necessari determin whether iddsi could well appli clinician patient without difficulti east asia countri evalu iddsi scale find difficulti appli scale east asia countri educ clinician patient may enrol physician nurs nutritionist swallow therapist involv dysphagia treatment singl center seoul evalu degre understand difficulti adapt iddsi clinician east asia countri use item questionnair iddsi sampl food food asian countri first item compar iddsi previous use scale base nation dysphagia diet ndd next question iddsi level answer absolut valu answer respons differ calcul iddsi show signific high intraclass correl previous use ndd base scale coeffici higher nutritionist swallow therapist evalu whether iddsi could appli well east asia countri absolut valu answer respons differ lower major level except level iddsi framework might success appli univers regardless food cultur worldwid standard food rheolog dysphagia treatment might possibl
|
D003680
|
T047
|
36,281,172
|
diagnost dilemma celiac diseas present weight loss secondari amenorrhea case report celiac diseas cd autoimmun enteropathi affect proxim small intestin mucosa caus insensit gluten protein predomin present wheat cd classic associ gastrointestin symptom non classic clinic present cd present organ involv non human leukocyt antigen gene associ atyp form
|
D002446
|
T047
|
36,281,171
|
cxcl act prognost biomark associ immun infiltr stomach adenocarcinoma stad rank th common incid malign tumor rd common death rate cancer worldwid cxc chemokin affect biolog progress various tumor result therapeut failur role cxcl stad still mysteri
|
D013274;D000230
|
T191
|
36,281,170
|
clinic efficaci safeti low dose doxepin chines patient general anxieti disord studi clinic anim studi report low dose doxepin may posit effect general anxieti disord gad howev effect clinic safeti less well understood studi studi aim investig effect side effect low dose doxepin evalu hamilton anxieti scale hama score hormon blood glucos serum lipid bodi weight bodi mass index bmi patient gad forti nine patient male femal gad random assign receiv low dose doxepin mg mg per day week februari march hama score fast blood glucos fbg bodi weight bmi serum biochem index adrenocorticotrop hormon acth free triiodothyronin ft total cholesterol tc triglycerid tg low densiti lipoprotein cholesterol ldlc fbg assess pretreat post treatment mean score hama decreas low dose doxepin treatment p serum level acth vs pmoll ft vs pgml tc vs mmoll tg vs mmoll ldlc vs mmoll fbg vs mmoll higher pretreat signific differ p bodyweight vs kg p bmi vs kgm p differ treatment result suggest low dose doxepin benefici clinic efficaci safeti low dose doxepin amelior anxieti gad patient effect neuroendocrin system metabol activ serum glucos lipid
|
D001786;D004316
|
T121;T109
|
36,281,169
|
follow care month patient bladder cancer spain multicent prospect cohort studi therapeut approach bladder cancer strong determin prognosi describ treatment outcom spanish cohort patient bladder cancer first month diagnosi identifi factor influenc decis undergo treatment receiv conduct multicent prospect cohort studi includ primari bladder cancer patient first month diagnosi clinic outcom perform status ecog advers event caus mortal stratifi analysi factor might influenc treatment receiv conduct univari multivari logist regress model assess patient tumor characterist associ receiv adjuv treatment subgroup noninvas bladder cancer patient total patient includ men year tertiari spanish hospit noninvas urotheli bladder cancer nmibc patient receiv most surgeri plus adjuv therapi bcg patient frequent administ adjuv therapi follow intraves chemotherapi patient radiotherapi variabl administ treatment among hospit low patient nmibc like receiv adjuv therapi higher educ level comorbid high grade tumor number fulli activ patient ecog signific decreas first year follow ci month follow patient die caus conclus patient nmibc surgeri alon plus adjuv therapi commonest curat option bladder cancer bcg therapi adjuv therapi frequent administ higher educ level presenc comorbid high grade tumor associ adjuv therapi patient perform status worsen time almost patient die first year follow
|
D001749
|
T191
|
36,281,168
|
safeti efficaci sofosbuvir velpatasvir meta analysi sofosbuvir velpatasvir singl tablet regimen epclusa newli fda approv inhibitor hepat c virus hcv meta analysi aim investig safeti efficaci velpatasvir sofosbuvir treatment chronic hcv infect
|
D006526;D000069474
|
T121;T047;T114;T109
|
36,281,167
|
long act drug peopl expect physician prepared readi manag italian survey evalu patient expect regard long act antiretrovir agent prefer receiv multicent cross section survey base studi onlin survey ask peopl live human immunodefici virus judg relationship daili antiretrovir therapi art give opinion long act drug also collect data regard age patient site follow time sinc diagnosi complianc art two hundr forti two patient age year includ studi femal male male femal transgend said popul good relationship art consid daili art oblig restrict freedom one hundr forti three patient alreadi knew long act drug interview patient interest one hundr fifti six interviewe said would still interest hospit avail inject long act drug although patient would rather receiv home data emerg survey reveal around peopl live hiv interest chang actual treatment long act one moreov first time knowledg high number patient show enthusiast respons new opportun treat direct home introduct new drug could revolutionari repres import step toward treatment simplif
|
D015658;D010820
|
T047;T097
|
36,281,166
|
clinicopatholog characterist prognosi colon cancer lung metastasi without liver metastasi larg popul base analysi distant metastasi explain high mortal rate colon cancer lung metastasi without liver metastasi lum rare subtyp studi aim identifi risk factor lum llm lung metastasi liver metastasi colon cancer analyz prognosi patient lum creat nomogram patient inform obtain surveil epidemiolog end result seer databas multivari logist regress analysi use determin risk factor lum llm prognost factor cancer specif surviv css overal surviv os identifi multivari cox proport hazard regress nomogram model establish predict css os multivari logist regress analysi show black splenic flexur colon tumor tumor size cm n higher lymph node posit rate associ occurr lum meanwhil age year old femal splenic flexur colon higher lymph node posit rate brain metastasi independ risk factor css c index predict model css ci addit age primari site tumor size differenti grade n stage bone metastasi signific differ lum llm nomogram creat effect predict surviv individu furthermor patient lum llm colon cancer might requir differ follow interv examin
|
D003110;D008113;D008175
|
T191
|
36,281,165
|
effect concentr sevofluran immobl cerebr palsi children undergo botulinum toxin inject prospect studi aim determin optimum end tidal sevofluran concentr requir immobl botulinum toxin inject spontan breath children cerebr palsi cp
|
D008738;D018685;D019274;D002547
|
T129;T121;T116;T109;T131;T019;T122;T047
|
36,281,164
|
lncrna alm novel prognost biomark correl immun infiltr colon adenocarcinoma colon adenocarcinoma coad one serious cancer import accur predict prognosi provid individu treatment evid suggest clinicopatholog featur immun status bodi relat occurr develop cancer express long non code rna lncrna alm intron transcript alm observ cancer type believ may potenti serv marker coad therefor use data obtain cancer genom atlas tcga databas prove relationship alm coad wilcoxon rank sum test chi squar test fisher exact test logist regress use evalu relationship clinic patholog featur alm express receiv oper characterist curv use describ binari classifi valu alm use area curv score kaplan meier method cox regress analysi use evalu factor contribut prognosi gene oncolog go kyoto encyclopedia gene genom kegg enrich analysi use predict function differenti express gene associ alm gene set enrich analysi gsea use predict canon pathway associ alm itimmun infiltr analysi perform identifi signific involv function alm starbas databas use predict mirna rna bind protein rbps may interact alm increas alm express coad associ n stage p stage p patholog stage p primari therapi outcom p receiv oper characterist curv suggest signific diagnost prognost abil alm area curv high alm express predict poorer overal surviv p poorer progress free interv pfi p alm express independ correl pfi coad patient hazard ratio hr ci p hr ci p go kegg gsea immun infiltr analysi show alm express correl regul function dna type immun infiltr cell alm express signific correl poor surviv immun infiltr coad may promis prognost biomark coad
|
D062085;D003110;D000230;D035683
|
T123;T191;T114
|
36,281,163
|
comparison incid prognosi young old gastric cancer patient north western china retrospect cohort studi gastric cancer gc fourth common cancer world second common cancer china studi compar clinicopatholog featur prognosi gc young old patient curat resect six hundr eighti six patient gc resect divid two group accord patient age younger gc patient year age ygc n older gc patient year age ogc n ygc group patient total gc patient ygc patient predomin women vs compar ogc patient year overal surviv exhibit differ tumor site tumor size macroscop type stage n stage rate n stage rn tumor node metastasi stage scope gastrectomi radic degre lymphat vascular invas within ygc ogc group univari analysi clinic factor affect overal surviv ygc group reveal signific differ tumor size macroscop type except borrmann stage except n stage na nb rn tumor node metastasi stage iii scope gastrectomi radic degre lymphat vascular invas gender n stage rn radic degre independ prognost factor younger patient gc similar result found ogc group signific differ radic degre lymphat vascular invas found male femal patient ygc group similar result found ogc group result show ygc patient differ ogc patient predomin women gender n stage rn radic degre independ risk factor prognosi ygc patient
|
D013274
|
T191
|
36,281,162
|
huangqi guizhi wuwu decoct peripher neurotox treatment use network pharmacolog molecular dock studi predict core activ compound huangqi guizhi wuwu decoct treatment oxaliplatin induc peripher neuropathi relat potenti mechan correspond databas use complet interact ppi network key target enrich analysi correspond genm molecular dock key target key compound carri use relev softwar chemic compon correspond oral absorpt huangqi guizhi wuwu decoct correspond uniqu target chemic compon correspond percutan absorpt vitro correspond uniqu target uniqu target chemotherapi induc peripher neuropathi final three common key target slca slca slca two key compound gingerol nuciferin screen accord three target dataset result show ppi network common key target involv associ protein relat go enrich result item relat biolog process item relat cell composit item relat molecular function four kegg pathway enrich l kinas gpcr perturb analysi show associ protein effect express multipl group kinas gene hpa reveal enrich three common key target tissu specif dock result show group structur stabl oral topic use huangqi guizhi wuwu decoct prevent control peripher neurotox prevent control effect may relat particip regul neurotransmitt transport sympathet activ transport histolog part mechan main distribut adren gland placenta brain intestin lung blood specif accord predict result molecular dock gingerol nuciferin close bind three common key target
|
D000970;D004365;D018696;D020258;D010523
|
T121;T123;T109;T037;T047;T169
|
36,281,161
|
signific analysi pax express endometri carcinoma analyz express prognost valu pair box pax express uterin corpus endometri carcinoma ucec bioinformat express pax gene ucec analyz r languag immunohistochemistri correl pax express clinicopatholog featur analyz r languag prognost factor analyz univariatemultivari regress surviv curv patient analyz kaplan meier plotter k plotter diagnost valu pax ucec analyz receiv oper characterist curv relationship pax express methyl analyz ualcan relationship methyl prognosi analyz methsurv databas express pax cancer tissu signific higher normal tissu express pax relat clinic stage age histolog type histolog grade tumor invas diseas specif surviv event univariatemultivari regress analysi show clinic stage tumor invas pax express influenc factor overal surviv os histolog grade pax express influenc factor diseas specif surviv patient low express longer os area curv receiv oper characterist curv pax diagnosi ucec pax hypomethyl cancer tissu patient hypermethyl pax longer os high express pax induc hypomethyl may play import role occurr prognosi ucec
|
D016889;D018269
|
T191
|
36,281,160
|
effect xuebij inject combin ulinastatin adjunct therapi sepsi overview systemat review meta analysi xuebij inject xbj increas use sepsi china aim evalu methodolog qualiti summar evid regard effect xbj combin ulinastatin uti sepsi systemat reviewsmeta analys srsmas
|
D004365;D018805
|
T123;T047;T121;T046
|
36,281,159
|
fecal calprotectin predict small bowel capsul endoscopi find pediatr patient known crohn diseas fecal calprotectin fc propos noninvas surrog marker intestin inflamm inflammatori bowel diseas studi aim assess capabl fc predict small bowel capsul endoscopi sbce find pediatr patient known crohn diseas cd retriev data consecut patient age year old establish cd underw sbce janurari april endoscop remiss ileocolonoscopi sixti eight patient includ analysi patient weight pediatr cd activ index patient fc gg patient signific small bowel sb inflamm lewi score ls ls correl weak fc r p area curv fc surrog diagnost test ls optim fc cutoff valu gg correspond sensit specif respect area curv fc moder sever inflammatori activ sb patient fc level gg ls found patient sensit specif respect fc may use predict sb mucos inflamm pediatr patient confirm cd endoscop remiss ileocolonoscopi
|
D053704;D003424
|
T060;T047
|
36,281,158
|
evalu new covid triag algorithm emerg depart includ combin antigen pcr test case control studi coronavirus diseas covid pandem major challeng global healthcar system earli safe triag emerg depart ed crucial proper therapi howev differenti diagnosi remain challeng rapid antigen test rat may help improv earli triag patient safeti perform retrospect studi consecut patient suspect covid present ed novemb underw sar cov nasopharyng swab test use rat revers transcript polymeras chain reaction rt pcr inpati treatment establish accord empir develop triag algorithm accuraci suggest algorithm analyz base rate outpati return within day inpati stay less hour covid inpati outpati compar symptom vital sign c reactiv protein level includ patient suspect covid infect diagnosi could confirm patient posit rt pcr result wherea posit antigen test covid outpati three return within day need hospit treatment due clinic deterior among covid inpati discharg within hour wherea stay longer mean durat day suggest triag algorithm safe effici first consecut patient rat confirm diagnosi pcr proven covid patient allow earli cohort isol import way save hospit capac
|
D000086382
|
T047;T067
|
36,281,157
|
ilra prognost indic correl immun characterist pancreat ductal adenocarcinoma pancreat ductal adenocarcinoma pdac high aggress incur cancer dismal prognosi studi aim explor potenti predictor prognosi immunolog characterist pdac estim stromal immun cell malign tumor use express data estim method appli calcul immun stromal score pdac sampl gse r packag limma util identifi differenti express gene deg gene ontolog go kyoto encyclopedia gene genom kegg enrich analys conduct function explor protein protein interact ppi network univari cox analysi conduct select key prognost gene pdac gene set enrich analysi gsea appli investig role ilra pdac singl sampl gsea ssgsea perform evalu immunolog characterist pdac sampl wilcoxon rank sum test conduct compar differ immunolog characterist pdac sampl low ilra high ilra spearman correl analysi use explor correl ilra express immun checkpoint gene total deg identifi low high immunestrom group function explor reveal upregul deg associ immun relat activ wherea downregul deg involv inflammatori relat activ ilra select critic gene overlap hub gene ppi network prognost gene signific ilra express signific elev pdac patient higher ilra express wors prognos immunolog oncogen role ilra pdac evidenc gsea furthermor pdac sampl high ilra express exhibit increas immun infiltr better immunotherapi respons ilra express posit correl pdcd cd ctla ido tdo tigt higher express ilra predict wors surviv outcom increas immun infiltr pdac pdac patient high ilra express might potenti benefit immunotherapi
|
D021441;D010190
|
T191
|
36,281,156
|
associ risk hepat virus relat hepatocellular carcinoma egf polymorph prisma compliant updat meta analysi studi aim provid comprehens account associ epiderm growth factor egf ag polymorph rs suscept virus relat hepatocellular carcinoma hcc
|
D006528;D008113;D006505
|
T047;T191
|
36,281,155
|
studi kyphoplasti year scienc map method kyphoplasti scienc map method bibliometr analysi perform scientif map techniqu purpos studi analyz articl kyphoplasti kyphoplasti minim invas surgic method bibliometr mathemat statist quantit analysi work one primari use bibliometr analysi scientif map
|
D058498
|
T061
|
36,281,154
|
network base pharmacolog studi mechan kaiyuzhongyutang treatment tubal fimbria obstruct appli network pharmacolog approach explor target possibl mechan kai yu zhong yu tang kyzyt treatment tubal fimbria obstruct target inform kyzyt extract tcmsp herb databas gene relat tubal fimbria obstruct search use genecard databas target protein network map ppi drawn use string databas analysi cytoscap softwar kyoto encyclopedia gene genom kegg pathway enrich analysi gene function analysi go enrich analysi perform help perl languag biolog program packag r languag explor multipl pharmacolog mechan action kyzyt intervent treatment tubal fimbria obstruct lay foundat experiment valid collect analysi multipl databas biolog target kyzyt identifi target tubal fimbria obstruct obtain diseas databas drug compon drug target network kyzyt construct protein interact network ppi overlap target analyz identifi key target drug affect diseas addit kegg pathway analysi go enrich analysi perform overlap target explor mechan kyzyt treatment tubal fimbria obstruct kyzyt characterist multi compon multi target multi pathway treatment tubal fimbria obstruct provid new idea scientif basi clarif molecular mechan
|
D008516;D004365
|
T060;T123;T121;T091
|
36,281,153
|
comprehens assess neurocognit function inflamm marker adipos treat hiv control compar neurocognit score person live human immunodefici virus plwh person without human immunodefici virus hiv assess relationship neurocognit hiv status variabl inflamm bodi composit measur cross section studi involv particip plwh antiretrovir therapi art person without hiv first time hiv use cognivu food drug administr fda approv comput base test assess cognit function test calibr individu uniqu cognit abil measur cognit domain perform paramet marker inflamm immun activ insulin resist bodi fat composit use dual energi x ray absorptiometri scan collect classic test chi squar test spearman correl use compar explor relationship variabl invers probabl weight adjust averag treatment effect model perform evalu differ plwh person without hiv adjust age race sex heroin use overal male black mean age year among plwh undetect hiv rna level copiesml compar person without hiv plwh perform poorer across domain visuospati p execut function p naminglanguag p abstract p addit plwh signific longer process speed time compar control ms vs ms p plwh lower cognit test domain score associ higher inflammatori marker high sensit c reactiv protein hscrp higher total fat viscer adipos tissu p neurocognit impair nci hiv associ inflamm total central adipos
|
D002097;D015658
|
T129;T047;T116
|
36,281,152
|
clinic prognost valu lncrna foxp cancer patient meta analysi bioinformat analysi base tcga dataset mortal recurr patient cancer high preval long non code rna lncrna forkhead box p antisens rna foxp promis lncrna increas evid lncrna foxp abnorm express various tumor associ cancer prognosi studi design identifi prognost valu lncrna foxp human malign
|
D062085;D009369
|
T123;T191;T114
|
36,281,151
|
applic dexamethason combin tranexam acid periop period total hip arthroplasti evalu efficaci safeti dexamethason dexa combin tranexam acid txa periop period total hip arthroplasti
|
D019644;D003907;D014148
|
T061;T121;T109
|
36,281,150
|
effect earli intervent manual lymphat drainag rehabilit exercis morbid lymphedema patient oral caviti cancer clinic statist inconsist regard earli intervent manual lymphat drainag mld purpos studi compar short term effect earli intervent rehabilit exercis versus mld rehabilit exercis term pain rang motion rom lymphedema patient oral cancer surgeri
|
D001943;D008209;D009062
|
T047;T191;T046
|
36,281,149
|
real world efficaci safeti dolutegravir plus lamivudin versus tenofovir plus lamivudin efavirenz art nave hiv infect adult limit real world data dolutegravir dtg plus lamivudin tc hiv infect individu report studi aim evalu real world efficaci safeti dtg tc art nave hiv infect adult china real world prospect observ cohort studi enrol hiv infect adult receiv art initi dtg tc group tenofovir plus lamivudin efavirenz tdf tc efv tle group subgroup low viral load lvl copiesml high viral load hvl copiesml accord baselin hiv rna efficaci assess proport virolog suppress chang cd cell count cdcd ratio hiv dna decay safeti symptom chang laboratori indic week total particip group tle group enrol proport hiv rna copiesml lvl subgroup week compar tle lvl subgroup p week proport hvl subgroup compar tle hvl subgroup p week virolog rebound observ group mean chang cdcd ratio higher lvl versus tle lvl subgroup schedul visit p cd cell count increas signific hvl versus tle hvl subgroup week p less complaint dizzi insomnia dreami amnesia lower elev level triglycerid higher elev level creatinin baselin week document group p total hiv dna decay along hiv rna dtg tc initi lvl hvl subgroup dtg tc achiev virolog suppress rapid stabli versus tdf tc efv art nave hiv infect adult better immunolog respons less advers drug effect reduc total hiv dna effect dtg tc potent regimen art nave individu hiv infect
|
D015497;D019380;D015658
|
T121;T005;T047
|
36,281,148
|
explor gancao xiexin decoct treatment behcet diseas base network pharmacolog molecular dock base network pharmacolog molecular dock studi discuss potenti mechan gancao xiexin decoct treatment behet diseas bd provid reliabl theoret basi treatment bd
|
D001528
|
T047
|
36,281,147
|
risk factor associ increas incid cathet relat bloodstream infect implement sever prevent measur reduc central line associ bloodstream infect clabsi general intens care unit icu univers hospit japan analyz factor associ clabsi patient central venous cathet cvc insert evalu effect implement prevent measur juli june data collect medic record patient cvc insert includ age sex acut physiolog chronic health evalu ii apach ii score durat icu stay durat cathet insert insert site mechan ventil status week confer surveil team compris intens care infect control doctor nurs determin patient clabsi status analyz factor compar clabsi central line patient without bloodstream infect multivari analysi reveal three factor associ clabsi adjust odd ratio confid interv follow durat icu stay durat cathet insert apach ii score promin risk factor associ sever initi condit exacerb clinic condit patient stay icu strategi reduc clabsi must develop
|
D055499;D002405;D062905;D018805;D016470
|
T061;T047;T046;T074
|
36,281,146
|
age relat chang knee flexor muscl strength cross section area weaken muscl strength around knee tend render vulner age relat damag studi aim examin associ knee flexor muscl strength cross section area csa also evalu age relat chang flexor muscl strength csa retrospect analyz patient acut onset knee pain month septemb august accord strengthen report observ studi epidemiolog statement csa knee flexor muscl bicep femori sartorius gracili semitendinosus st semimembranosus sm measur magnet reson imag axial imag suprapatellar level evalu flexor muscl strength peak torqu nm use cybex dynamomet second second correl csa total patient mean age year rang year men women includ studi signific intergroup differ demograph data sex bodi mass index found mean csa mm sm mm bicep femori mm sartorius mm st mm gracili mean peak torqu nm nm second second respect csa posit correl flexion strength second r p second r p muscl strength associ csa muscl gracili r p flexion strength decreas signific age thirti total csa decreas age r p csa bicep femori sartorius sm st decreas signific wherea gracili tend decreas non signific age flexor muscl strength associ total muscl csa magnet reson imag csa everi muscl except gracili flexion strength decreas signific age twenti total csa decreas signific age csa flexor muscl decreas signific age wherea gracili decreas slight
|
D007719;D018482
|
T023;T024;T030
|
36,281,145
|
demograph clinic characterist pediatr covid arkansa march decemb covid pandem reach unit state earli spread rapid across countri retrospect studi describ demograph clinic characterist children present arkansa children emerg depart ed admit arkansa children hospit covid first month covid pandem prior emerg clinic signific variant avail vaccin adolesc age older repres largest proport popul common present symptom fever gastrointestin symptom upper respiratori symptom patient multisystem inflammatori syndrom children mis c longer length stay los patient acut covid children urban zip code lower odd admiss like readmit discharg near twenti percent studi popul incident test posit covid despit lower mortal children covid adult morbid resourc util signific mani arkansa children live rural area therefor far pediatr hospit communiti hospit prepar evalu children present covid determin children warrant transport pediatr specif facil
|
D000086382
|
T047;T067
|
36,281,144
|
efficaci safeti dual antiplatelet therapi percutan coronari drug elut stent network meta analysi evalu efficaci safeti dual antiplatelet regimen coronari drug elut stent network meta analysi nma
|
D062645;D009203;D013927;D020521;D012749
|
T061;T047;T046
|
36,281,143
|
preval diabet nephropathi diabet mellitus popul protocol systemat review meta analysi diabet nephropathi dn lead caus end stage renal diseas worldwid place enorm pressur healthcar system creat heavi socioeconom burden urgent comprehens studi epidemiolog characterist dn diabet patient analyz relat factor incid order implement effect prevent control measur
|
D003928;D003924
|
T047
|
36,281,142
|
prognost factor diabet comparison chi squar automat interact detector chaid decis tree technolog logist regress studi aim develop diabet predict model model perform compar logist regress decis tree chi squar automat interact detect chaid use predict diabet total patient includ analysi patient diabet patient without diabet includ analyz studi sampl korean genom epidemiolog studi koge data studi diabet mellitus dm diagnosi predict compar logist regress predict machin learn ml use chaid decis classif tree perform statist analysi use chaid method intern busi machin ibm statist program spss perform logist regress analysi predict classif diabet accur total classif accuraci analysi chaid decis tree classif accuraci diabet diagnosi decis tree creat includ seven termin node three depth level analysi show blood pressur problem hospit visit decis variabl time classif two risk level creat diabet diagnosi suggest method valuabl tool predict diabet patient visit hospit blood pressur problem like develop diabet treat hyperlipidemia diabet predict model help doctor make decis detect possibl diabet earli howev imposs diagnos diabet use model without doctor opinion
|
D003920
|
T047
|
36,281,141
|
influenc continu posit airway pressur lipid profil obstruct sleep apnea systemat review meta analysi investig influenc continu posit airway pressur cpap lipid profil patient obstruct sleep apnea osa meta analysi
|
D045422;D020181
|
T061;T047
|
36,281,140
|
delay encephalopathi covid case seri six patient acut encephalopathi sever neurolog complic coronavirus diseas covid case acut encephalopathi associ covid occur within sever week covid onset describ case seri patient develop delay encephalopathi de covid
|
D001927;D000086382
|
T047;T067
|
36,281,139
|
metformin therapi strategi compens anti vegf resist patient diabet macular edema diabet macular edema dme complic diabet retinopathi lead caus vision loss among diabet patient metformin main antidiabet treatment prefer great anti angiogen anti inflammatori effect anti vascular endotheli growth factor vegf therapi prefer treatment dme despit lack convinc result patient assess whether combin metformin anti vegf drug may decreas risk anti vegf resist among dme patient includ dme patient central retin thick crt consecut underw least anti vegf therapi januari decemb anti vegf resist defin persist macular edema decreas crt anti vegf inject patient consid research resist anti vegf therapi mean crt non metformin group decreas p metformin group moreov metformin group fewer resist patient non metformin versus furthermor consider gain visual acuiti observ group bcva gain metformin group non metformin group metformin may combin anti vegf drug minim risk anti vegf resist among dme patient moreov serv design effect therapeut deliveri
|
D003920;D003930;D008269;D008687
|
T121;T047;T109
|
36,281,138
|
long term effect hematopoiet growth factor aplast anemia patient treat immunosuppress meta analysi random control trial immunosuppress therapi frontlin treatment aplast anemia patient inelig transplant long term effect hematopoiet growth factor hgf ad standard immunosuppress therapi still unclear perform systemat review meta analysi clarifi issu
|
D000741;D007153
|
T047
|
36,281,137
|
vitamin supplement patient alopecia areata protocol systemat review meta analysi sever studi report associ low vitamin vd level alopecia areata aa suggest vd prepar potenti therapi vd immunomodulatori function close associ varieti skin diseas conclus evid support vd supplement patient aa therefor conduct meta analysi collect evalu efficaci safeti vd supplement treatment aa
|
D000506
|
T047
|
36,281,136
|
triphalang thump thumb duplic syndactyli first case report literatur triphalang thumb tpt rare congenit malform thumb three phalang instead two syndactyli condit children born fuse web finger combin tpt syndactyli thumb duplic extrem rare especi deform combin one hand
|
D013576;D006228;D017689
|
T019
|
36,281,135
|
effect endur surgic treatment target therapi relat paronychia retrospect studi develop target therapi improv treatment outcom patient non small cell lung cancer nsclc howev paronychia common advers effect target therapi remain burdensom although conserv treatment paronychia well report literatur studi efficaci surgic partial matricectomi paronychia scarc studi aim evalu effect surgic partial matricectomi target therapi induc paronychia patient nsclc retrospect cohort studi includ patient total lesion big toe data lung cancer stage type durat target therapi onset paronychia pain scale score conserv treatment cours matricectomi paronychia free interv matricectomi wound condit collect medic record wilcoxon sign rank test use analysi mean pain scale score matricectomi signific lower conserv treatment vs p treatment vs p mean durat matricectomi signific shorter conserv treatment vs week p surgic partial matricectomi effect endur intervent target therapi relat paronychia provid shorter cours treatment reduc pain improv appear heal wound furthermor surgic partial matricectomi could result better qualiti life target therapi conserv treatment
|
D002289;D008175;D010304
|
T047;T191
|
36,281,134
|
humor immun respons bntb mrna covid vaccin patient rheumat diseas undergo immunosuppress therapi japanes monocentr studi investig serum total antibodi titer sever acut respiratori syndrom coronavirus sar cov spike protein receptor bind domain bntb mrna vaccin coronavirus diseas covid japanes patient take various immunosuppress medic rheumat diseas outpati rheumat diseas kagawa univers hospit healthi volunt control receiv dose bntb vaccin serum antibodi titer sar cov spike protein analyz least day second dose mani patient take immunosuppress agent manag rheumat diseas antibodi titer sar cov spike protein patient signific lower control analysi therapeut agent reveal antibodi titer patient treat rituximab much lower control patient treat tacrolimus baricitinib azathioprin mycophenol mofetil abatacept tumor necrosi factor inhibitor cyclosporin interleukin inhibitor methotrex glucocorticoid antibodi titer moder lower control interleukin interleukin inhibitor impair humor respons addit combin methotrex various immunosuppress agent reduc titer although signific japanes patient rheumat diseas mani immunosuppress impair immun respons bntb vaccin degre declin antibodi titer differ accord immunosuppress use concomit immunosuppress methotrex may impair immun respons bntb vaccin howev immunomodulatori treatment interleukin inhibitor may attenu respons patient rheumat diseas
|
D000090982;D000086382;D056724;D007165;D012216
|
T061;T129;T121;T116;T067;T109;T200;T040;T114;T043;T047
|
36,281,133
|
exploratori analys biomark blood stratum corneum patient atop dermat pathogenesi atop dermat ad involv various mediat includ cytokin chemokin produc immun cell dendrit cell lymphocyt non immun cell epiderm cell sever mediat includ thymus activ regul chemokin tarc use biomark ad sever activ howev addit local system biomark ad requir
|
D003876
|
T047
|
36,281,132
|
rare magnet reson imag find intracrani solitari fibrous tumor case report solitari fibrous tumor sft rare mesenchym spindl cell tumor sft central nervous system cns rare case report rare magnet reson imag mri find intracrani sft isft
|
D054364;D006393;D008579;D008577
|
T191
|
36,281,131
|
sarcopenia among peopl live hiv effect antiretrovir therapi bodi composit investig preval sarcopenia among peopl live hiv plwh japan analyz relationship hiv infect art effect bodi composit japanes plwh appropri drug select lifestyl guidanc cross section observ studi includ male patient age year whose bodi composit measur inbodi bodi composit analyz outpati visit patient classifi bodi shape base bodi mass index bmi bodi fat percentag measur tenofovir alafenamid administr hidden obes condit wherein bmi within standard rang bodi fat percentag higher refer patient low muscl mass strength consid sarcopenia wherea low muscl strength consid pre sarcopenia total patient includ base bodi shape determin bmi bodi fat percentag patient hidden obes patient sarcopenia detect patient pre sarcopenia patient tenofovir alafenamid taf use group signific higher bmi higher skelet muscl mass bodi fat mass skelet muscl mass index relat non taf use group hidden obes risk lifestyl diseas import recogn base bodi composit measur miss bmi measur alon tenofovir alafenamid therapi increas skelet muscl mass may result prevent sarcopenia clarifi taf affect develop sarcopenia lifestyl diseas futur studi larger cohort warrant
|
D055948;D015658
|
T047
|
36,281,130
|
express profil prognost valu smc famili member hcc structur mainten chromosom smc gene famili includ protein involv wide rang biolog function differ human cancer nevertheless littl research express pattern potenti function prognost valu smc gene hepatocellular carcinoma hcc base public avail databas integr bioinformat analysi tri determin valu smc gene express predict risk develop hcc
|
D006528;D008113
|
T191
|
36,281,129
|
diagnost perform corona virus diseas chest comput tomographi imag recognit base deep learn systemat review meta analysi analyz diagnosi perform deep learn model use corona virus diseas covid comput tomographi ct chest scan includ sampl contain healthi peopl confirm covid patient unconfirm suspect patient correspond symptom
|
D000086382;D000077321
|
T047;T066;T067
|
36,281,128
|
comparison f fdg petct ultrasound stage patient malign melanoma evalu sensit specif fluoro deoxi glucos positron emiss tomographycomput tomographi f fdg petct ultrasound us stage patient malign melanoma
|
D019788;D008545
|
T191;T130;T109
|
36,281,127
|
factor affect prevent behavior alzheim diseas famili member patient alzheim diseas genet factor increas risk alzheim diseas ad famili dementia patient risk ad aim evalu factor affect prevent behavior ad famili member ad patient use construct questionnair base health belief model hbm theoret framework cross section studi investig factor influenc prevent behavior ad intent take ad prevent medicin prior experi take cognit function supplement ad prevent lifestyl famili member ad patient recruit korea alzheim caregiv associ particip intent take ad prevent medicin experi take cognit function supplement intent take ad prevent medicin signific influenc self efficaci odd ratio confid interv ci dementia knowledg ci wherea prior experi cognit function supplement signific associ cue action ci ad prevent lifestyl signific influenc socio demograph age sex marit status hbm factor perceiv suscept self efficaci cue action self efficaci cue action dementia knowledg perceiv suscept signific associ prevent behavior ad also famili member dementia patient risk dementia due genet factor lifestyl environ factor high level ad prevent lifestyl strong intent take ad prevent medicin research could suggest understand ad prevent behavior intent take ad prevent medicin general popul
|
D000544
|
T047;T048
|
36,281,126
|
red blood cell indic effect marker exist sever endometriosi strobe evalu associ red blood cell rbc indic mean corpuscular volum mcv mean corpuscular hemoglobin mch mch concentr mchc red cell distribut width rdw hemoglobin hb hematocrit hct neutrophil lymphocyt ratio nlr sever endometriosi data obtain medic record patient endometriosi stage iii stage iiiiv group patient benign ovarian tumor control group treat septemb april mean hb hct signific lower stage iiiiv group compar control stage iii group p p respect mean mcv mch hb postop day pod signific lower stage iiiiv group compar control stage iii group p p p respect addit nlr pod signific higher stage iiiiv group compar control stage iii group multivari analysi reveal younger age year old lower preoper mcv fl lower pod hb independ risk factor stage iiiiv endometriosi lower level rbc indic includ preoper mcv postop hb higher postop nlr signific associ sever endometriosi potenti deriv dysregul iron metabol inflamm
|
D004909;D004715
|
T191;T059;T033;T081;T047;T034
|
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