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biomedical-topic-categorization-validation

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36,281,125
associ night sleep latenc hypertens cross section studi sleep disord shown increas risk hypertens relationship night sleep latenc hypertens less well known aim investig associ night sleep latenc hypertens well relat sleep factor gender chines popul conduct cross section studi relationship night sleep latenc hypertens sampl size includ consecut hospit patient mf year test chi squar test anova perform analyz baselin data intergroup comparison spearman correl analysi perform find interrelationship multivari logist regress analysi perform adjust covari find show hypertens patient longer night sleep latenc p adjust confound factor night sleep latenc posit correl hypertens men women odd ratio confid interv spearman correl analysi suggest night sleep latenc posit correl systol blood pressur r p diastol blood pressur r p sleep initi time r p global pittsburg sleep qualiti index score r p negat correl sleep durat r p sleep time weekday r p sleep time weekend r p longer night sleep latenc associ increas risk hypertens men women might involv patholog progress hypertens along sleep factor
D006973;D012893
T047;T048
36,281,124
cardiac cta imag qualiti adapt statist iter reconstruct v versus deep learn reconstruct truefidel children congenit heart diseas sever recent studi report deep learn reconstruct truefidel tf improv comput tomographi ct imag qualiti howev studi compar adapt statist repeat reconstruct asir v use tf pediatr cardiac ct angiographi cta low peak kilovoltag
D000077321;D006330
T019;T066
36,281,123
red cell distribut width glasgow coma scale score predictor hospit mortal mainten hemodialysi patient diagnos spontan intracerebr hemorrhag glasgow coma scale gcs score wide use use predictor investig patient head injuri high red cell distribut width rdw valu independ associ mortal poor neurolog outcom howev data avail spontan intracerebr hemorrhag sih mainten hemodialysi mhd patient studi aim evalu prognost valu combin measur rdw gcs score mhd patient sih retrospect studi mhd patient admit hospit nontraumat sih octob may data includ demograph inform caus renal failur comorbid esrd clinic laboratori paramet admiss collect medic record univari multivari logist regress analysi perform identifi independ risk factor hospit mortal hemodialysi patient sih receiv oper characterist curv roc area curv auc determin sensit specif independ risk factor calcul rang differ cutoff point total patient enrol studi hospit mortal rate divid subject group base clinic outcom compar survivor n non survivor n longer hemodialysi vintag p lower gcs score p higher hemoglobin hb p rdw p multivari logist regress analysi gcs score ci p rdw ci p independ risk factor hospit mortal mhd patient sih area roc curv auc gcs score ci rdw ci auc combin predict ci sensit specif conclus high rdw low gcs score use independ poor prognost marker hospit mortal mhd patient sih
D004909;D002543
T059;T033;T081;T046;T034
36,281,122
analysi epidemiolog characterist predict chang pattern infecti diarrhea oid covid china studi describ epidemiolog featur transmiss infecti diarrhea oid epidem covid china lay foundat oid prevent control incid rate mortal data oid contain detail epidemiolog inform date age region total oid case number obtain data center china public health scienc nation bureau statist statist yearbook joinpoint regress model z test use analyz r languag arcgi draw autoregress integr move averag model use predict influenc covid oid oid incid rate increas million million mortal rate decreas male femal incid ratio p patient age show decreas trend age p scatter children devot oid incid rate bimod distribut oid incid summer peak northern china appar peak central eastern winter peak southern autoregress integr move averag model predict compar actual oid case affect epidem control measur covid number oid case declin absolut percentag error oid incid rate china continu increas show bimod distribut summer winter inconspicu region characterist gender age suscept differ occup differ meanwhil covid signific reduc oid incid discoveri might bring benefici effect oid prevent control polici
D000086382;D004403
T047;T067
36,281,121
effect aftercar program suicid ideat real world evid nation suicid surveil system taiwan aftercar program effect suicid ideat seldom report studi assess rate factor relat recurr suicid relat episod index suicid ideat episod index case famili member receiv aftercar secondari data analysi suicid ideat episod individu report nation suicid surveil system new taipei citi taiwan januari june follow septemb among index suicid ideat recurr suicid relat episod includ suicid ideat attempt death within year index ideat recurr signific reduc index case receiv aftercar twice three four higher famili member receiv aftercar twice associ reduc suicid index case receiv aftercar among index case associ woman suicid due occupationfin report suicid hotlin receiv aftercar among famili member associ index case age year old suicid reason relat school occupationfin report school hospit aftercar program suicid ideat famili member adolesc suicid ideat age year old decreas subsequ episod suicid behavior
D013406;D013405
T033;T037;T048
36,281,120
mobil applic home exercis adher patient knee osteoarthr pilot studi adher home exercis general low despit well known effect knee osteoarthr therefor develop home exercis applic longlifesupport provid patient daili basic exercis video automat record calendar hypothes applic would encourag patient exercis help maintain motiv pilot studi aim determin exercis adher rate use outcom measur also aim determin effect home exercis use applic factor continu
D020370;D063731
T047;T170
36,281,119
efficaci safeti acupunctur chemotherapi induc leukopenia systemat review meta analysi leukopenia one common type myelosuppress secondari chemotherapi main method use treat leukopenia chemotherapi various limit sever studi report role acupunctur prevent treatment leukopenia qualiti studi uneven use systemat review meta analysi evalu efficaci safeti acupunctur treatment leukopenia chemotherapi
D026881;D015670;D007970;D000970
T061;T121;T091;T109;T047
36,281,118
aberr express long non code rnas peripher blood mononuclear cell respons tuberculosi children aim identifi long non code rnas lncrnas aberr express peripher blood mononuclear cell pbmcs trigger activ tuberculosi atb latent tuberculosi infect ltbi healthi control hc examin lncrnas express pbmcs isol children atb ltbi hc use rna sequenc gene ontolog go kyoto encyclopedia gene genom kegg pathway analysi use explor biolog process signal pathway aberr express mrnas total lncrnas differenti express atb ltbi group respect compar hc group compar ltbi group lncrnas differenti express atb group compar hc group mrnas differenti express atb group mrnas differenti express ltbi group compar ltbi group mrnas differenti express atb group upregul mrnas main enrich neutrophil activ neutrophil mediat biolog process posit regul immun respons tuberculosi tb wherea downregul mrnas enrich signal pathway structur process wnt signal pathway rdna heterochromatin assembl first studi differenti express lncrnas pbmcs children tb identifi signific differ express profil lncrnas mrnas pbmcs children atb ltbi hc import implic explor lncrnas novel biomark diagnosi tb addit experiment identif valid lncrna role could help elucid under mechan mycobacterium tuberculosi infect children
D062085;D014376;D055985
T123;T047;T114
36,281,117
risk factor stratif postop delirium retrospect databas studi ehr patient year age undergo surgeri pod assess review patient characterist studi variabl summar delirium group construct univari logist regress model pod use studi variabl estim odd ratio construct multivari logist regress model stepwis variabl select order creat clinic usefulimplement tool creat nomogram predict risk delirium
D011183;D003693
T046;T048
36,281,116
construct valid novel prognost model thyroid cancer base n methylguanosin modif relat lncrnas construct verifi novel prognost model thyroid cancer thca base n methylguanosin modif relat lncrnas mg lncrnas associ immun cell infiltr
D062085;D013964
T123;T191;T114
36,281,115
real world compar effect bdmard jak inhibitor elder patient rheumatoid arthriti retrospect cohort studi compar retent rate effect biolog diseas modifi antirheumat drug bdmard target synthet dmard target diseas modifi antirheumat drug tsdmard janus kinas inhibitor jaki elder patient ra one hundr thirti four elder ra patient year initi bdmard n jaki n institut enrol analysi follow conduct week interv start bdmard jaki compar drug retent clinic respons week elder ra patient treat bdmard jaki demograph data diseas durat proport previous bdmard use less proport glucocorticoid use jaki group signific observ compar bdmard group otherwis signific differ variabl bdmard jaki group jaki group drug retent rate signific differ compar bdmard group hr ci p also signific differ proport patient achiev good moder european allianc associ rheumatolog eular respons week two group bdmard vs jaki p elder ra patient initi bdmard jaki drug retent rate target therapi differ signific two group find suggest elder ra patient achiev similar clinic improv initi bdmard jaki
D000075242;D018501;D001172;D001688
T121;T047;T123
36,281,114
ustekinumab effect ulcer coliti intestin stenosi case report intestin strictur obstruct rare complic ulcer coliti uc current studi treatment uc intestin stenosi howev report treatment uc benign intestin stenosi ustekinumab ust
D003093;D007415
T047
36,281,113
effect hospit base low intens inspect aerob train function cardiorespiratori fit uncondit stroke patient import submaxim aerob fit marker purpos studi evalu effect low moder intens aerob train cardiorespiratori function chronic uncondit stroke patient oxygen uptak effici slope oue ventilatori threshold vo vt could repres aerob capac submaxim test studi examin applic submaxim paramet evalu aerob capac chronic stroke patient
D000072599;D020521
T047;T040
36,281,112
prognost risk stratif model metastat small cell lung cancer analysi seer databas distant metastas small cell lung cancer dm sclc import factor select treatment strategi studi establish nomogram predict dm sclc determin benefit radiotherapi rt dm sclc analyz dm sclc prognosi base surveil epidemiolog end result databas seer data comprehens practic nomogram predict overal surviv os dm sclc construct result compar th edit american joint committe cancer ajcc tnm stage system concord index c index receiv oper characterist plot generat evalu nomogram discrimin calibr evalu calibr plot effect evalu decis curv analysi dca score assign variabl total score establish risk stratif model total dm sclc patient includ eight characterist variabl identifi independ prognost variabl c index valid train cohort respect area receiv oper characterist curv auc valu nomogram use predict year os valid cohort train cohort respect calibr curv year surviv rate show predict nomogram good agreement actual observ nomogram exhibit higher clinic util evalu year dca compar ajcc stage system predict nomogram risk stratif model construct evalu prognosi dm sclc effect accur nomogram may provid refer prognosi stratif treatment decis
D055752;D008175
T191
36,281,111
discuss molecular mechan duhuo jisheng decoct treat osteoarthr base network pharmacolog molecular dock studi network pharmacolog molecular dock technolog use explor molecular mechan duhuo jisheng decoct treatment osteoarthr oa chemic composit prescript obtain tradit chines medicin system pharmacolog databas analysi platform tcmsp databas retriev literatur target activ ingredi obtain use tcmsp swiss target predict databas diseas target obtain genecard disgenet databas onlin tool venni use obtain common target drug diseas protein protein interact ppi common target analyz use search tool retriev interact genesprotein string databas common target analyz gene ontolog go kyoto encyclopedia gene genom kegg pathway enrich use databas annot visual integr discoveri david databas molecular dock first target first compon verifi use autodock tool softwar dock diagram visual use pymol softwar screen chemic compon duhuo jisheng decoct dhjsd identifi common target drug diseas combin elimin repeat valu base ppi network analysi top ten target src stat mapk mapk rela pikr hspaa tp ep akt kegg analysi show dhjsd could regul hif pik akt jak stat signal pathway biolog process involv includ inflammatori reaction negat regul apoptosi posit regul cell prolifer molecular dock result show target except rela protein show good bind compound indic compon might exert therapeut effect bind target dhjsd treat oa regul hif pik akt jak stat signal pathway protein involv src stat mapk mapk pikr studi network pharmacolog use predict mechan dhjsd oa treatment verifi molecular dock provid experiment research idea scientif basi oa treatment
D019869;D010003
T047;T126;T116
36,281,110
effect vibrat train delay muscl sore meta analysi delay onset muscl sore dom caus unaccustom exercis especi eccentr exercis high like caus skelet muscl injuri main manifest ultrastructur chang skelet muscl well decreas muscl strength muscl sore swell elev level creatin kinas ck vibrat train vt attract increas attent new type rehabilit therapi effect minim occurr reliev symptom dom reduc muscl stiff sore reduc serum concentr ck lactat dehydrogenas ldh articl systemat assess impact vt mitig dom meta analysi provid updat evid base inform
D063806;D014732
T184;T070
36,281,109
investig report endoscop manag esophagogastr varic bleed chines endoscopist esophagogastr varic bleed egvb potenti life threaten complic portal hypertens endoscop treatment combin pharmacotherapi remain mainstay manag acut varic bleed
D004932;D014014;D019168;D014648
T061;T047;T122;T020
36,281,108
relationship flexor extensor muscl area presenc degre intervertebr disc degener cervic region studi aim investig relationship presenc degre cervic intervertebr disc degener ivdd cervic region muscl area
D055959;D007403
T047;T023;T190
36,281,107
vascular photobiomodul treatment children temporomandibular disord studi protocol random control blind clinic trial studi aim verifi use intravascular laser irradi blood ilib influenc reduct pain increas rang motion open close mouth children adolesc temporomandibular disord tmd
D028022;D013705
T061;T047
36,281,106
intestin obstruct caus small bowel entrap within lumbar fractur case report intestin obstruct associ traumat vertebr fractur extrem rare report case obstruct small bowel injuri caus entrap small intestin fractur site th lumbar vertebra due trauma
D016103;D007415;D050723
T047;T037
36,281,105
lipoma osteocartilagin metaplasia infrapatellar fat pad case report review literatur lipoma tumor compos matur adipocyt origin mesoderm common soft tissu tumor accord world health organ classif human soft tissu bone tumor type benign tumor includ matur adipos tissu osteolipoma known rarest subtyp lipoma
D008067
T191
36,281,104
hematocrit elev sglt inhibitor administr may associ degre proxim tubular damag renal protect effect sglt inhibitor known due elimin glomerular hypertens improv hypoxia oxid stress proxim tubul therefor increas hematocrit hct level hypothes indic restor tubular function improv renal prognosi analyz relationship hct decreas estim glomerular filtrat rate egfr sglt inhibitor administr backward medic record data data patient continu sglt inhibitor year analyz decreas egfr administr sglt inhibitor defin slope b factor statist signific associ slope b multipl regress analysi systol blood pressur sbp p short term decreas egfr sglt inhibitor administr initi dip p hct p urin protein p find opposit hypothesi hct marker indic improv renal prognosi may reflect extent proxim tubular disord administ sglt inhibitor
D000077203;D003924
T121;T047;T109
36,281,103
isol myeloid sarcoma pericardi pleural effus first manifest case report myeloid sarcoma ms involv prolifer extramedullari blast myeloid lineag replac origin tissu structur neoplasia call granulocyt sarcoma chloroma extramedullari myeloid neoplasm tumor develop lymphoid organ bone skin soft tissu various mucous membran organ central nervous system ms rare non leukem patient ms patient effus first manifest even rare
D023981;D015470;D010996
T047;T191
36,281,102
predict renal damag children iga vascul base machin learn articl object explor valu machin learn algorithm predict risk renal damag children iga vascul construct predict model analyz relat risk factor iga vascul nephriti children case data hospit children iga vascul novemb octob collect data includ indic demograph characterist clinic symptom laboratori test etc univari featur select use featur extract logist regress support vector machin svm decis tree random forest rf algorithm use separ classif predict last perform four algorithm compar use accuraci rate recal rate auc accuraci rate recal rate auc establish rf model respect higher logist regress model higher svm model higher decis tree model top import featur provid rf model persist purpura week cr clinic time alb wbc tc relaps tg recurr purpura eb dna model base rf algorithm better perform predict children iga vascul renal damag indic better classif accuraci better classif effect better general perform
D011695
T047
36,281,101
vitamin children pneumonia covid perspect systemat review meta analysi trial systemat review meta analyz efficaci vitamin adjuv therapi pneumonia children
D000086382;D011014
T047;T050;T067
36,281,100
appropri dialysi modal select process cross section studi studi specif quantifi appropri process dialysi modal select lack periton dialysi pd offer clinic social advantag hemodialysi hd may underus aim determin appropri process dialysi modal select quantifi percentag patient could potenti pd candid perform cross section studi includ adult patient hospit nephrolog depart barcelona start dialysi assess appropri dialysi modal select defin sequenti domain base critic step choos dialysi modal elig either treatment inform modal share decis make obtain data use medic record patient questionnair dialysi modal select process consid appropri patient contraind select option receiv complet inform modal voluntarili chose select option total patient includ studi median age year interquartil rang year patient men dialysi modal select process potenti inappropri particip problem relat inform dialysi modal share decis make appropri pd use potenti increas patient age lack inform regard dialysi option independ associ potenti degre inappropri dialysi modal select find indic area improv select dialysi modal better educ share decis make number patient pd could potenti doubl analysi appropri help approach studi renal replac treatment pattern identifi strategi optim use
D007676;D010530;D009398
T061;T047;T091
36,281,099
two dimension speckl track echocardiographi power method evalu anthracyclin induc left ventricular insuffici anthracyclin one import therapeut method breast cancer therapi decad howev serious long term toxic especi cardiotox limit continu usag anthracyclin henc affect long term prognosi earli detect myocardi dysfunct treatment critic challeng two dimension speckl track echocardiographi ste non doppler techniqu assess deform strain track displac acoust marker myocardium studi aim compar sensit precis ste tradit echocardiographi monitor left ventricular function patient breast cancer anthracyclin therapi key indic evalu myocardi chang thirti three patient breast cancer recruit februari decemb patient treat cycl anthracyclin ste convent echocardiographi perform patient two dimension echocardiograph examin use collect data interventricular septum diamet ivsd end diastol left ventricular posterior wall diamet lvpwd left ventricular end diastol diamet lvedd left ventricular systol parastern left ventricular long axi view final diamet left ventricular end systol diamet lvesd left ventricular short axi shorten rate lvfs measur type two plane simpson method use measur left ventricular end diastol volum lvedv end systol volum left ventricular end systol volum lvesv obtain left ventricular eject fraction lvef two dimension speckl track imag technic indic includ left ventricular global longitudin strain lvgls subendocardi myocardi longitudin strain lvgls endo epicardi myocardi longitudin strain lvgls epi correl dimension speckl track imag convent ultrasound paramet analyz compar baselin systol function paramet lvef signific chang four cycl chemotherapi p meanwhil two dimension strain paramet lvgls lvgls endo lvgls epi statist signific cycl chemotherapi p two dimension strain paramet gls higher accuraci sensit monitor left ventricular insuffici caus anthracyclin therapi compar tradit echocardiographi
D018943;D001943
T191;T109
36,281,098
peak oxygen uptak respiratori muscl perform patient chronic obstruct pulmonari diseas clinic find implic maxim oxygen uptak vomax gold standard measur aerob exercis capac import outcom measur patient chronic obstruct pulmonari diseas copd respiratori muscl perform also import function paramet copd patient addit tradit respiratori muscl strength test test increment respiratori endur recent introduc valid patient copd howev relationship vo respiratori muscl perform copd well understood therefor studi investig correl among vo respiratori muscl perform function marker copd total patient copd enrol studi particip underw follow assess cardiopulmonari exercis test pulmonari function test respiratori muscl strength test peripher muscl strength test bioelectr imped analysi compar vopeak respiratori muscl paramet sustain maxim inspiratori pressur smip factor signific relationship vopeak among function paramet forc expiratori volum one second fev show strongest correl vopeak follow phase angl valu lower limb leg extens peak torqu age total skelet muscl mass compar respiratori muscl perform function paramet smip show strongest correl hand grip strength follow peak cough flow forc vital capac maxim inspiratori pressur fev result show smip signific correl vopeak static measur respiratori muscl strength suggest tire may use assess tool patient copd addit fev function marker signific correl vopeak suggest various paramet may use evalu aerob power indirect
D018737;D029424
T081;T047;T040
36,281,097
compar effect differ platelet rich plasma arthroscop rotat cuff repair protocol systemat review network meta analysi rotat cuff tear one common injuri shoulder joint adult arthroscop rotat cuff repair arcr becom gold standard treatment rotat cuff injuri still high rate retear platelet rich plasma prp wide use adjunct arcr howev compar efficaci differ prp arcr remain unclear order evalu relat efficaci prp individu arcr conduct systemat review network meta analysi random control trial
D000070636;D053657
T033;T047;T037;T031
36,281,096
kinesio tape ankl sprain youth athlet protocol systemat review meta analysi ankl sprain consid major problem may hinder youth athlet athlet develop lead ongo dysfunct reoccurr ankl sprain chronic ankl instabl posttraumat osteoarthr kinesio tape kt therapeut tape techniqu wide use treatment various ankl issu includ sprain ankl prevent ankl sprain provid injur ankl support rehabilit phase also enhanc ankl stabil activ howev avail evid regard effect treatment prevent ankl sprain inconsist therefor systemat review help clinician coach better understand applic kt clinic train practic studi systemat review literatur use kt improv outcom includ ankl function propriocept pain evalu effect kt treatment prevent ankl sprain injuri
D016512;D055052
T074;T037
36,281,095
survey clinic laboratori characterist dengu fever epidem zhejiang china explor epidem clinic laboratori characterist dengu patient zhejiang possibl mechan epidem clinic laboratori data dengu patient admit second affili hospit zhejiang tradit chines medicin univers august decemb collect gse dataset download gene express omnibus databas use immun cell infiltr analysi logist regress analysi nomogram construct gene set enrich analysi gsea perform explor possibl regulatori pathway dengu infect receiv oper characterist curv analysi decis curv analysi conduct evalu valu relat immun cell predict dengu sever among patient gender ratio malefemal patient year age group respect major symptom fever weak anorexia muscl joint pain nausea dengu patient serum sampl decreas platelet level decreas white blood cell wbc level elev aspart aminotransferas level elev lactat dehydrogenas level increas creatinin level increas creatin kinas level pneumonia pleural effus bilater pleural reaction observ respect dengu patient gallbladd wall rough splenomegali account case moreov level cell b cell dendrit cell signific higher convalesc group involv immun metabol relat pathway note low level immun cell correl high dengu infect risk dendrit cell exhibit satisfactori perform predict dengu sever dengu fever patient often onset fever accompani mild abnorm blood system organ function moreov cell b cell dendrit cell might involv dengu infect develop
D003715
T047
36,281,094
random control trial compar incid postop nausea vomit laparoscop cholecystectomi preoper intraven fluid load ondansetron control group region hospit set develop countri postop nausea vomit ponv common complic inpati outpati set multimod approach pursu minim undesir outcom despit consensus guidelin manag ponv updat publish mani year data pilot studi show patient high risk surgeri ponv laparoscop cholecystectomi lc still hard receiv periop ponv prophylaxi studi aim compar incid ponv adult patient undergo elect lc administ preoper intraven fluid load ondansetron neither fluid ondansetron set region hospit develop countri
D017081;D000932
T061;T121;T039
36,281,093
provid uptak extragenit screen gonorrhea chlamydia cohort air forc member incid hiv diagnosi preval neisseria gonorrhea gc chlamydia trachomati ct higher extragenit anatom site among men sex men msm hiv infect although nation guidelin recommend msm hiv infect undergo screen extragenit sexual transmit infect eg stis uptak low mani primari care set evalu eg sti screen primari care provid pcps us air forc usaf member incid hiv infect usaf member incid hiv infect receiv initi hiv specialti care infecti diseas id provid brook armi medic center n includ retrospect chart review conduct evalu sti screen perform pcps within week hiv diagnosi compar screen entri id care demograph clinic laboratori behavior risk data collect sti screen includ gcct eg stis urethr gcct syphili hepat b c patient predomin male median age iqr year hiv diagnosi previous histori stis report patient major male self identifi msm bisexu median time hiv diagnosi id evalu day iqr pcps perform sti screen patient eg sti screen conduct patient overal msmbisexu total patient miss stis major due eg stis rectum pharynx eg stis would miss urethr gcct screen alon eg sti screen uptak low among pcps evalu usaf member incid hiv infect underutil eg sti screen result miss infect forward transmiss gcct barrier low uptak need explor
D002690;D006069;D015658;D008889
T047;T097
36,281,092
meta analysi aerob exercis improv intellig cognit function patient alzheim diseas alzheim diseas ad neurodegen diseas studi aim explor intervent treatment effect aerob exercis differ exercis mode ad meta analysi
D000544;D019636
T047;T048
36,281,091
success control intestin bleed metastasi pulmonari pleomorph carcinoma pembrolizumab case report pulmonari pleomorph carcinoma rare tumor poor prognosi standard chemotherapi herein report case small intestin metastasi pulmonari pleomorph carcinoma result intestin bleed success treat pembrolizumab monotherapi
D008175;D002277
T191
36,281,090
telephon follow clinic pharmacist improv treatment outcom patient peptic ulcer prospect random studi purpos studi investig effect pharmaceut care clinic pharmacist telephon follow treatment outcom patient peptic ulcer discharg hospit
D016481;D010437;D016480;D000897
T121;T047;T007
36,281,089
surviv perivi birth babi birth weight g case report increas number perivi birth newborn pvbs emerg concurr grow high risk pregnanc date postnat manag pvbs remain one challeng issu limit studi report
D001997;D012127;D007232
T047
36,281,088
comparison flexibl fixat screw fixat isol lisfranc ligament injuri protocol meta analysi compar studi frequenc isol lisfranc ligament ill injuri increas recent increas low energi trauma result sport injuri ill injuri optim method fixat still remain controversi tradit fixat method achiev tran articular screw recent dorsal bridg plate sutur button sb fixat becom altern biomechan studi show sb fixat provid adequ strength compar tran articular screw therefor meta analysi imper provid evid whether flexibl fixat compar screw fixat treatment ill injuri
D001863;D008023
T023;T074
36,281,087
social mental impact healthcar worker compar cross section studi two wave covid pandem taiwan coronavirus diseas covid pandem caus heavili burden healthcar worker hcws worldwid aim studi compar differ psycholog social impact two wave pandem among first second line hcws taiwan current studi deriv data two cross section survey conduct level depress sleep disturb psycholog distress social impact demograph variabl collect self report questionnair independ test use compar differ score first second wave pandem differ first second line hcws also analyz total hcws first wave hcws second wave recruit first second line hcws social impact second wave higher first wave express higher intent maintain social distanc awar pandem oversea second wave first line hcws trend wors sleep qualiti second wave addit sleep qualiti wors first line hcws second line hcws wave second line hcws express greater desir seek covid relat inform first line hcws first wave intend maintain social distanc second wave result show import evalu social mental health burden hcws especi first line worker
D058873;D000086382
T047;T067
36,281,086
iga nephropathi mimick fabri diseas case report literatur review fabri diseas fd rare inherit diseas lysosom storag disord caus lack alpha galactosidas enzym genet diseas affect men women understand fd import condit effect treat women may exhibit normal residu enzym activ diagnosi challeng
D000795;D005922
T047
36,281,085
anesthet manag epilepsi surgeri patient previous diagnos takotsubo cardiomyopathi case report takotsubo cardiomyopathi tc also known stress cardiomyopathi apic balloon syndrom octopus pot cardiomyopathi broken heart syndrom character wall motion abnorm left ventricl
D054549;D009202;D004827;D000777
T033;T121;T047;T039
36,281,084
lymphocyt subset pd express lymphocyt peripher blood patient non small cell lung cancer incid rate mortal rate lung cancer lc high studi aim analyz lymphocyt subset program death pd express lymphocyt peripher blood non small cell lung cancer nsclc patient explor whether chang cellular immun nsclc peripher blood sampl collect newli diagnos nsclc patient healthi individu lymphocyt subset pd express evalu use flow cytometri singl sampl gene set enrich analysi ssgsea perform explor correl pd express infiltr pattern tumor infiltr immun cell flow cytometri two popul lymphocyt nsclc patient observ apart popul normal volum lymphocyt lym popul larger volum particl lym compar healthi group proport cd cell pd express lym higher cd cell lower nsclc group nsclc group proport cd cell cd cell cdcd dpt cell pd express higher lym lym p ssgsea show tumor infiltr immun cell posit correl pd express pd express lymphocyt increas recurr patient treat pd inhibitor lym may tumor infiltr lymphocyt til upregul pd express nsclc pd express lymphocyt may use recurr indic nsclc patient treat pd inhibitor
D002289;D008175
T191
36,281,083
botulinum toxin inject strategi intract relaps piriformi syndrom case report piriformi syndrom ps neuromuscular disord caus sciatic nerv compress piriformi muscl relat sciatic type pain conserv care fail local inject surgeri also perform piriformi recent year botulinum toxin bont also consid new therapeut option piriformi syndrom
D055958;D020426;D001905;D017116
T121;T184;T116;T131;T047
36,281,082
identif verif gene signatur predict overal surviv cervic cancer cervic cancer cc one common gynecolog malign rank fourth incid mortal women worldwid earli screen treatment great signific reduc incid mortal cc due complex molecular mechan tumor progress predict power tradit clinic inform limit studi effect molecular model establish assess prognosi patient cc guid clinic treatment improv surviv rate three high qualiti dataset gse gse gse express profil obtain gene express omnibus geo databas anoth mrna express clinicopatholog data cc obtain cancer genom atlas tcga dataset bioinformat analys univari analysi multivari cox proport hazard model cox analysi lasso regress analysi conduct select surviv relat differenti express gene deg establish prognost gene signatur moreov perform prognost gene signatur evalu base kaplan meier curv receiv oper characterist roc curv gene set enrich analysi gsea tumor immun analysi carri elucid molecular mechan immun relev gene signatur compris procollagen lysin oxoglutar dioxygenas plod spondin spon secret phosphoprotein spp ribonucleas h subunit rnaseha establish predict overal surviv os cc roc curv indic good perform gene signatur predict os cc base tcga dataset gene signatur classifi patient high risk low risk group distinct os rate cc univari analysi multivari cox regress analysi reveal gene signatur independ factor affect prognosi patient cc studi develop gene signatur capabl predict os cc find may benefici individu clinic treatment time follow patient cc
D002583
T191
36,281,081
diagnost accuraci gastric fill ultrasonographi preoper invas depth stage gastric cancer meta analysi studi aim evalu diagnost valu gastric fill ultrasonographi preoper invas depth stage gastric cancer
D013274
T191
36,281,080
intens modul radiotherapi might effect local advanc esophag carcinosarcoma singl center experi review literatur esophag carcinosarcoma rare type esophag cancer howev studi investig effect radiotherapi local advanc patient studi aim report experi safeti efficaci intens modul radiotherapi local advanc esophag carcinosarcoma review literatur search institut databas januari decemb along literatur review patient elig studi clinic radiolog inform patient esophag carcinosarcoma underw radiotherapi collect surviv outcom calcul use kaplan meier plot seri patient curativeneoadjuv radiotherapi group patient adjuv group tumor protrud n patient underw intens modul radiotherapi curativeneoadjuv radiotherapi group patient underw concurr chemoradiotherapi surgeri three receiv radiotherapi alon initi treatment median follow time month patient show partial respons efficaci evalu median time overal surviv progress free surviv month confid interv ci month month ci month month entir cohort reach curativeneoadjuv radiotherapi group overal surviv hazard ratio hr ci p progress free surviv hr ci p differ signific group consid literatur review data final analysi overal surviv hr ci p progress free surviv hr ci p also differ group treatment base intens modul radiotherapi neoadjuv curat intent may option patient unresect esophag carcinosarcoma research larger sampl size need valid reliabl
D050397;D004938;D000077277;D002296
T061;T191
36,281,079
compound heterozyg protein c defici pulmonari embol caus novel proc gene mutat case report literatur review protein c anticoagul agent protein c defici result vascular thrombosi diseas hereditari protein c defici risk factor pulmonari embol adult pathogen variant protein c inactiv coagul factor va viiia proc gene encod protein c identifi caus protein c defici
D020151;D011655;D013927
T047;T046
36,281,078
associ medic therapi beta blocker inhibitor renin angiotensin system clinic outcom patient mild reduc left ventricular eject fraction acut myocardi infarct era initi optim intervent medic therapi acut myocardi infarct ami number patient mild reduc left ventricular eject fraction ef increas observ studi aim investig associ medic therapi oral beta blocker inhibitor renin angiotensin system ras year clinic outcom patient mild reduc ef ami among patient enrol korea acut myocardi infarct registri nation institut health propens score match patient surviv initi attack mild reduc ef select accord beta blocker ras inhibitor therapi discharg beta blocker therapi discharg associ lower year major advers cardiac event composit cardiac death myocardi infarct revascular hospit due heart failur vs patient year hazard ratio hr confid interv ci p signific interact ef observ pinteract associ main driven lower myocardi infarct patient beta blocker hr ci p inhibitor ras discharg associ lower hospit due heart failur vs patient year hr ci p without signific interact ef pinteract patient mild reduc ef ami medic therapi beta blocker ras inhibitor discharg associ better year clinic outcom
D009203;D006333;D018487
T047;T046
36,281,058
diagnosi treatment acquir factor viii defici case report literatur review acquir haemophilia aha rare haemorrhag diseas character spontan extens subcutan haemorrhag soft tissu haematoma activ partial thromboplastin time signific prolong correct normal plasma approxim aha patient lack specif aetiolog easili result misdiagnosi current case report describ year old male present gingiv bleed haematuria haematochezia obvious caus first thought might experienc anticoagul rodenticid poison subsequ anticoagul rodenticid test negat time patient screen mutat associ bleed coagul diseas two mutat identifi pyh mutat plasminogen activ tissu type plat gene pyy mutat serpin famili e member serpin gene note patient previous histori thrombosi haemorrhag diseas confus diagnosi profession haemophilia research centr provid clarif diagnosi anti factor viii antibodi detect patient treat mgday prednison oral multipl follow examin show continu complet remiss factor viii antibodi detect blood coagul factor viii increas signific
D006467;D012378;D015843
T121;T123;T116;T131;T047
36,281,056
tb migrant resid netherland least year diagnosi background one challeng tb elimin low incid countri relat high incid tb migrant countri even multipl year residenceobject describ compar tb incid characterist migrant tb patient resid netherland least year diagnosi non foreign born tb patient order identifi addit strategi could reduc tb incid former groupmethod retrospect cohort studi conduct migrant somalia morocco surinam turkey indonesia diagnos tb netherland tb incid calcul multivari logist regress use identifi differ characterist tb patient per countri birth compar non foreign born patientsresult tb incid highest individu somalia popul follow individu morocco non foreign born popul tb incid differ characterist tb patient compar non foreign born patient vari countri birthconclus find underlin import awar heterogen tb incid characterist patient migrant popul resid year netherland
D014171;D014376
T047;T098
36,281,051
quantif multidrug resist tuberculosi bacilli sputum first week treatment set mulago hospit kampala ugandaobject quantifi mycobacterium tuberculosi sputum first week pulmonari multidrug resist tb mdr tb treatmentdesign enrol consecut adult pulmonari mdr tb treat accord nation guidelin collect overnight sputum sampl treatment week sputum sampl cultur middlebrook hs agar measur coloni form unit per ml cfuml mgit media measur time detect ttd linear mix effect regress use estim relat chang log cfuml ttdresult twelv adult median age year enrol half women two third hiv posit baselin median log cfuml decreas log cfumlweek median ttd h increas ttd hweek week chang greater first week log cfumlweek hweek remain week log cfumlweek hweek conclus serial quantit cultur measur indic slow uneven rate declin sputum tuberculosi week standard pulmonari mdr tb treatment
D014397;D018088;D009169
T047;T007
36,281,049
work relat interstiti lung diseas true burden interstiti lung diseas ild includ larg varieti fibrot lung condit caus genet environment factor occup exposur might also play signific role real health burden current unknown aim evalu role work relat exposur ild focuss idiopath pulmonari fibrosi ipf hypersensit pneumon hp perform focus review literatur work relat hp ipf past year use meta analyt approach quantifi occup burden ipf hp estim occup exposur metal silica environment tobacco smoke increas ipf risk pool odd ratio ci proport hp case relat workplac exposur ci review support hypothesi occup exposur signific risk factor aetiopathogenesi ipf hp recommend research perform identifi under occup factor maximum permit exposur reduc associ ipf hp burden
D014028;D017563;D000542;D054990
T033;T047;T069
36,281,048
scope review intervent mitig common non communic diseas among peopl tb background recommend made integr screen common non communic diseas ncds within tb program howev must ensur screen tie evid base intervent scale aim map exist evid regard intervent address ncds common affect peopl tbmethod systemat search pubm medlin embas studi evalu intervent mitig respiratori diseas cardiovascular diseas alcohol substanc use disord mental health disord among peopl tb exclud studi screen comorbid result intervent also exclud studi focus smoke cessat intervent evid base guidelin well establishedresult search identifi studi met inclus criteria common evalu intervent referr diabet care studi intervent includ pulmonari rehabilit studi care program alcohol use disord studi psychosoci support individu counsel studi conclus limit robust evid support identifi intervent chang individu outcom signific knowledg gap remain long term durabl intervent clinic benefit reach effect implement research demonstr feasibl effect need scale
D000073296;D019966
T033;T047;T048
36,281,045
ecg monitor stream stage identifi increas risk qt prolong background stream standardis treatment regimen anti tuberculosi drug patient multidrug resist tuberculosi stage randomis trial short month regimen rifampicin resist tb rr tb qt qtcf prolong ms occur short regimen particip frequent ecg monitor employ might challeng treatment programm analysi aim determin whether higher risk sever qt prolong could identifi earli target monitoringmethod data first month treatment use investig whether particip risk develop qtqtcf ms qtcf increas baselin differ time point examin absolut qtcf measur categoris ms increment time point discrimin time point qtcf cut off combin optimis sensit specificityresult absolut qtcf valu discrimin magnitud increas baselin particip develop qtqtcf ms qtcf respect ms ms h week p lt combin qtcf valu ms h ms week identifi high risk particip sensit negat predict valueconclus reduc ecg monitor may possibl mani short regimen particip
D008133;D012293
T121;T109;T033;T047;T195
36,281,043
pattern characterist tb among key risk group canada background canada low incid tb although certain group disproportion affectedobject describ compar epidemiolog trend characterist tb quebec canada among patient report method demograph risk factor compar three group account tb diagnos report quebec foreign born canadian born non indigen inuit averag annual incid incid rate ratio irr estim compar use poisson regressionresult person first episod tb foreign born canadian born non indigen inuit averag annual incid foreign born canadian born non indigen inuit respect per popul compar canadian born non indigen irr foreign born inuit respect ci ci evid communiti transmiss among inuit patient tb contact data diagnos age lt yearsconclus although tb rate among canadian born non indigen extrem low persist distinct tb epidem among foreign born inuit tailor approach tb prevent care need address tb among high risk popul low tb incid set
D014376;D054624
T047;T080
36,281,042
cost tb servic approach summari find multi countri studi valu tb background current larg gap unit cost data tb substanti variat qualiti method unit cost estim uncertainti remain sampl size rang comprehens cost data collect differ purpos present method result project implement kenya ethiopia india philippin georgia estim unit cost tb servic focus find relev remain methodolog challeng method estim financi econom unit cost close collabor nation tb programm gold standard method includ top bottom approach resourc use measur cost present usd local currenc unit result cost driver output vari servic across countri level capac ineffici substanti variat unit cost estim intervent high overhead cost observ estim subject sampl uncertainti data gap remain conclus paper describ detail method largest tb cost effort date inform prioritis plan tb servic studi provid strong baselin cost estim may extrapol data howev regular studi similar qualiti need add estim remain gap add new chang servic intervent research need best approach extrapol cost data cost studi best implement partnership polici maker generat communiti mutual learn capac develop
D017048
T081
36,281,040
factor influenc treatment outcom patient isoniazid resist pulmonari tb introduct patient isoniazid h inh resist pulmonari tb undetect rifampicin r rif resist treat month regimen levofloxacin rif ethambutol pyrazinamid lvxrez india nation tb elimin programm ntep object describ profil treatment outcom patient pulmonari inh resist inhr tb initi tb treatment identifi factor associ unfavour treatment outcom die fail treatment chang lost follow method retrospect analysi ntep databas ni kshay pulmonari inhr tb patient initi treatment h monopoli regimen lvxrez juli june document treatment outcom proport confid interv ci calcul logist regress analysi performedresult patient pulmonari inhr tb treatment success cure treatment complet unfavour treatment outcom observ male sex tobacco alcohol use hiv reactiv status associ unfavour treatment outcom patient katg mutat resist fluoroquinolon like poor treatment outcomesconclus levofloxacin base regimen offer treatment success rate patient pulmonari inhr tb sex specif strategi intervent address smoke alcohol use focus hiv reactiv patient optimis treatment regimen base drug suscept consid improv treatment outcom
D014397;D015658
T047
36,281,039
improv access afford qualiti assur inhal medicin low middl incom countri background access afford inhal medicin chronic respiratori diseas crds sever limit low middl incom countri lmic caus avoid morbid mortal intern union tuberculosi lung diseas conven stakehold meet topic februari method focus group discuss inform literatur present summaris experi obtain inhal medicin lmic virtual meet moder use topic guid around barrier solut improv access themat framework approach use analysisresult total key stakehold includ patient healthcar practition member nation intern organis industri repres attend meet pre meet materi submiss main barrier identifi low awar crds limit data crd burden treatment lmic ineffect procur distribut network poor communic need peopl crds solut discuss generat data inform polici practic capac build improv procur mechan strengthen advocaci practic world health assembl resolutionconclus opportun achiev improv access afford qualiti assur inhal medicin lmic coordin multi stakehold collabor effort
D003906;D012120
T047;T080
36,281,035
oppos effect egf receptor signal prolifer differenti initi egf tshegf receptor transactiv regul thyroid cell thyrotropin tsh epiderm growth factor egf known differ effect regul prolifer differenti report studi respons primari cultur human thyroid cell determin whether tsh receptor tshr signal may involv egf receptor egfr transactiv confirm egf stimul prolifer de differenti wherea tsh caus differenti absenc growth factor show tshtshr transactiv egfr character follow tsh induc upregul thyroid specif gene inhibit inhibitor egfr kinas activ ag erlotinib mechan transactiv independ extracellular egfr ligand show antibodi cetuximab panitumumab complet inhibit bind egfr ligand egfr effect transactiv demonstr egf detect media condit thyrocyt incub tsh tshtshr transactiv egfr differ egfr activ egf show egf led rapid phosphoryl egfr wherea transactiv occur absenc receptor phosphoryl egf caus downregul egfr wherea transactiv effect egfr level egf tsh stimul converg protein kinas b akt pathway tsh like egf stimul phosphoryl akt inhibit egfr inhibitor tsh induc upregul thyroid gene inhibit akt inhibitor mk thus tshtshr caus egfr transactiv independ extracellular egfr ligand part mediat tsh regul thyroid hormon biosynthet gene
D051057;D004815
T125;T121;T126;T116
36,281,031
chemotherapi combin immunotherapi primari femal urethr squamous cell carcinoma case report primari femal urethr carcinoma uncommon low morbid rate patient advanc ill high invas poor prognosi standard treatment multimod therapi recommend use radiotherapi chemotherapi most report previous studi advanc femal urethr squamous cell carcinoma report chemotherapi combin program death pd inhibitor effect treat metastat femal urethr squamous cell carcinoma four cycl use system chemotherapi albumin paclitaxel carboplatin combin pd inhibitor toripalimab mg everi week complet respons achiev perform genet test patient tumor mutat burden mutationsmb tumor proport score combin posit score c recurr distant metastasi found month follow conclus patient posit pd ligand express primari femal urethr squamous cell carcinoma chemotherapi combin pd inhibitor may effect larger sampl studi requir determin pd ligand express curat effect pd inhibitor well effect surviv
D008175;D002294;D014523
T191
36,281,030
vaccin reduc risk alzheim diseas parkinson diseas neurodegen disord neurodegener increas problem age alzheim diseas ad parkinson diseas pd frequent form age relat neurodegener infecti diseas general confer risk ad influenza pneumonia vaccin reduc risk ad vaccin pneumonia age associ reduct risk ad afterward protect bacteri viral infect benefici brain sinc infect may activ dormant herp simplex type hsv herp zoster virus hzv hsv hzv may interact trigger ad shingl hzv vaccin zostavax reduc risk ad pd find consist link virus neurodegener herp virus induc reactiv embryolog pathway silenc birth could one patholog process ad pd embryolog reactiv occur brain older person ad pd develop complex process relentless destroy protect mechan creat utero unansw question ad risk reduc effect flu pneumonia shingl vaccin cumul
D053061;D000544;D010300;D006562;D006561;D018259
T129;T121;T005;T047;T048
36,281,029
immunotherapi sepsi induc infect clinic evid potenti target sepsi life threaten organ dysfunct caus maladjust bodi respons infect abnorm immun respons play import role progress sepsi immunomodulatori therapi promis therapeut strategi sepsi great effort made recent elucid mechan immun dysfunct contribut sepsi identifi potenti biomark target diagnosi therapi sepsi induc emerg pathogen especi sever acut respiratori syndrom coronavirus sar cov caus covid review summar recent progress understand immun dysregul involv sepsi highlight potenti biomark target evalu immun status patient sepsi individu precis immunotherapi
D000086382;D018805
T047;T046;T067
36,281,028
methylprednisolon induc acut pancreat case present acut pancreat one lead gastrointestin caus hospit unit state drug induc acut pancreat rare acut pancreat case balani grendel base current public medic potenti caus drug induc acut pancreat articl present case year old man treat high dose methylprednisolon three day prior present symptom accord acut pancreat detail evalu patient medic histori exclus probabl etiolog confirm diagnosi methylprednisolon induc pancreat treatment support care withdraw offend agent diagnosi drug induc pancreat remain challeng clinician case may add evid role methylprednisolon drug induc acut pancreat also serv remind look close patient histori medic caus acut pancreat immedi found
D010195
T047;T046
36,281,027
qualiti life trigemin nerv block refractori trigemin neuralgia retrospect cohort studi literatur review evalu effect trigemin nerv block tnb patient qualiti life qol day procedur patient refractori tn
D014277
T047
36,281,023
case acut lymphoblast leukaemia diseas pancreat mass first symptom confirm elastographi combin eus fna haematolog diseas pancreat mass first symptom clinic rare ignor case report describ year old femal patient acut leukaemia pancreat mass first symptom patient admit elastographi combin endoscop ultrasound eus guid fine needl aspir biopsi eus fna use diagnosi treatment plan determin prognosi site select eus fna punctur caudal section pancreat bodi posterior wall gastric bodi use punctur point elastographi view head pancrea bluegreen predomin blue colour g punctur needl slow draw core two stitch micro negat pressur use cytolog detect heterotyp cell pancreat punctur histopatholog presenc pancreat alveolar structur heterotyp tumour cell interstitium immunohistochemistri pancreat punctur tissu show b cell lymphoblast deriv tumour bone marrow punctur indic acut lymphoblast leukaemia patient diagnos acut lymphoblast leukaemia invad pancrea treat chemotherapi treatment condit stabl follow ongo sign tumour recurr metastasi
D054459;D010190;D054198
T060;T191
36,281,005
unusu case intestin obstruct due meckel diverticulum vitellin cyst case report meckel diverticulum md common congenit anomali gastrointestin tract occur popul male symptomat femal case year old male present sudden onset colicki abdomin pain bilious vomit absolut constip emerg laparotomi done virgin abdomen result md vitellin cyst along fibrous cord connect two identifi knot ileal loop around cord result intestin obstruct meckel diverticulectomi along cord resect carri patient made smooth recoveri discharg fifth postop day complic import studi highlight case symptomat md adult male caus intestin obstruct alway consid patient present symptom intestin obstruct
D008467;D007415;D003560
T019;T047;T190
36,281,002
recent advanc manag hemipleg shoulder pain stroke debilit neurolog disord hemiplegia common present hemipleg shoulder pain hsp affect larg number stroke survivor associ signific morbid low qualiti life qol etiolog multifactori therefor manag multiprong tradit oral analges advis physic therapi intra articular steroid inject narrat review discuss emerg treatment strategi hsp focus four key new treatment electr stimul use robot intraarticular inject novel anti inflammatori agent puls radiofrequ treatment multipl studi assess efficaci techniqu found efficaci side effect profil compar superior current manag strategi hsp integr intervent multidisciplinari rehabilit programm stroke patient improv manag hsp reduc stroke relat morbid disabl
D020069;D020521
T184;T047
36,281,001
f fdg pet ct super scan paediatr rhabdomyosarcoma rhabdomyosarcoma rms common paediatr soft tissu sarcoma make diagnos case complex diseas potenti aris tissu bodi except bone four type rhabdomyosarcoma embryon botryoid alveolar pleomorph f fdg pet ct play vital role stage respons evalu follow diseas due signific morbid mortal high risk diseas proper stage paramount import stage rhabdomyosarcoma depend tumour local infiltr local structur primari tumour nodal involv presenc viscer metastas without time intervent rhabdomyosarcoma progress exponenti speed
D019788;D012208
T191;T130;T109
36,281,000
intraop seizur awak craniotomi brain tumour awak craniotomi ac becom increas popular brain tumour surgeri procedur allow better preserv eloqu cortex help achiev greater tumour resect howev potenti problem procedur intraop seizur io may affect map monitor awak patient may even lead abandon awak procedur
D014851;D001932
T191;T041
36,280,999
baro bulli ignor comorbid live obes obes longer consid result simplist voluntari inequ excess intak calori inabl expend physic activ though calori imbal occur said biolog driven under genet mechan associ alter orexigen anorex hormon hypothalamus howev despit recognis obes diseas stigma associ obes still big problem societi manuscript propos term baro bulli provid holist overview stigma encompass differ aspect downstream effect individu diseas process also propos differ method reduc barobulli across spectrum diseas process
D009765;D058445
T047;T048
36,280,998
lemborex adjuv difficult control diabet diabet multi facet syndrom brain etiopathogenet factor well target organ damag drug act brain bromocriptin antipsychot drug known influenc glycaem control articl describ lemborex dual oxexin receptor antagonist dora hypothes may use adjuv difficult control diabet util explor person insomnia high fast glucos unregul appetit diabet distress
D014150;D007319;D003920
T121;T184;T047;T039;T048
36,280,997
weight gain thyroid women coexist confound hypothyroid obes common coexist ill impact data india suggest third individu obes overt hypothyroid one tenth subclin hypothyroid multipl mechan describ thyroid obes could signific impact moder elev tsh elev lower classic describ thyroid dysfunct patient obes articl detail epidemiolog pathogenesi clinic implic weight gain thyroid dysfunct special focus women
D007037;D013959
T047
36,280,996
manag extens frontal pyocoel use extern approach case report pyocoel paranas sinus pus fill caviti seen sinus develop infect mucocoel pyocoel common form frontal sinus endoscop sinus surgeri current mainstay treatment present case year old femal present ent opd jinnah hospitalaimc lahor octob complaint progress symptom intract left frontal pain doubl vision associ swell medial half left eyebrow ct scan done diagnosi extens frontal pyocoel made treat success extern approach remain without complic till month follow surgeri except cosmet result achiev wish bring attent possibl extern approach use primari intervent deem appropri
D010254;D009078;D005626
T047;T190;T030
36,280,995
solitari rib metastasi primari nasopharyng carcinoma rare clinic present report case middl age male present tertiari care univers hospit complaint nasal obstruct decreas hear ct scan head neck exhibit mass nasopharynx enlarg bilater cervic lymph node biopsi nasopharynx confirm lesion poor differenti non keratin squamous cell carcinoma stage ctnm receiv neoadjuv chemotherapi subsequ underw chemo radiat therapi repres left chest wall pain imag confirm isol lesion left side th rib rib lesion resect follow radiat therapi surgic bed system treatment patient remain diseas free year later diseas relaps die system diseas progress best author knowledg case report isol rib metastasi nasopharyng carcinoma first case metastasectomi consid
D059146;D009303
T061;T191
36,280,994
sudden sensorineur hear loss rare present dengu fever sudden sensorineur hear loss ssnhl describ hear loss least db three frequenc pure tone audiogram day less caus may infecti vascular system immun mediat idiopath multipl viral infect associ ssnl howev dengu fever rna viral diseas direct transmit mosquito genus aed report present ssnhl thrice exist literatur best knowledg multipl differ propos mechan ssnhl viral infect multipl virus proven caus hear loss howev dengu virus one major case ssnhl exact caus difficult determin report case gentleman unilater ssnhl dengu fever
D003639;D006319;D014777;D003715
T033;T184;T047
36,280,993
primari thyroid lymphoma case seri patient develop countri primari thyroid lymphoma ptl rare diseas most affect middl old age femal strong associ pre exist thyroid increas risk develop diseas studi detail western popul howev lack data south asian especi pakistani popul studi carri learn diseas characterist area retrospect studi review four diagnos andor treat case primari thyroid lymphoma tertiari care hospit pakistan aga khan univers hospit karachi pakistan patient medic record review studi particip averag age year two male two femal histolog patient compat diffus b cell lymphoma subtyp one patient die result complic one patient lost follow remain two patient well activ complaint follow regular basi
D008223;D013964
T191
36,280,992
prenat diagnos larg intrapericardi rhabdomyoma without haemodynam compromis cardiac rhabdomyoma common primari cardiac tumour consid hamartoma develop embryon cardiac myocyt common seen tuber sclerosi size locat tumour surrog determin risk haemodynam compromis pericardi rhabdomyoma rare tend follow inher natur histori spontan regress present case two foetus diagnos larg pericardi rhabdomyoma haemodynam consequ
D012207;D005315;D014402;D006338
T047;T191
36,280,991
innov way break stone master lithoclast bilater simultan percutan nephrolithotomi object studi evalu efficaci master lithoclast also known trilog lithoclast simultan bilater percutan nephrolithotomi pcnl studi prospect case seri involv patient undergo bilater simultan pcnl male femal mean age subject year guy stone score patient classifi group group ii remain patient place group iii total oper time observ minut complet stone clearanc observ patient conclus studi data confirm master lithoclast provid faster stone clearanc unaffect composit stone eas usabl improv tissu safeti reduc chanc fragment block key factor
D000074642;D009403;D007669;D008096
T061;T047
36,280,990
bodi composit profil obes analysi healthi adult cross section studi obes depict chang bodi composit consid global epidem st centuri predispos cardiometabol diseas analyt cross section studi evalu bodi composit paramet gender conduct obes analysi healthi adult pakistani popul use non probabl purpos sampl techniqu data collect healthi adult age year particip structur exercis dietari regim last six month bodi composit assess use bioelectr imped analys data analysi descript statist mann whitney u test one sampl test appli mean bodi mass index kgm bodi composit compon signific higher male includ soft lean mass fat free mass index skelet muscl mass index bone miner content wherea femal signific higher percentag bodi fat pbf viscer fat area fat mass index p obes analysi mean pbf sampl higher white hispan european adult major healthi adult greater bodi fat mass lower skelet muscl mass primari obes index signific higher pakistani popul compar ethnic femal exhibit higher trend toward obes
D000273;D001823
T201;T032;T024
36,280,989
superscan f fdg pet ct imag lymphoma frequent retrospect studi conduct evalu frequenc pet superscan baselin stage scan lymphoma patientsth studi conduct shaukat khanum memori cancer hospit lahor octob august retrospect review baselin pet ct scan lymphoma patient perform period octob august done institut databas patient pet superscan pattern observ patient male femal eight patient non hodgkin lymphoma hodgkin lymphoma base tnm stage patient stage iv diseas stage iii diseas stage ii diseas pet ct superscan pattern uncommon depend stage diseas recognis clinic practic suggest poor prognosi
D019788;D008223
T191;T130;T109
36,280,988
effect decompress pain rang motion function patient acut vs chronic lumbar radiculopathi purpos studi determin effect manual lumbar decompress pain rang motion function patient acut vs chronic lumbar radiculopathi thirti patient fulfil elig criteria tehsil headquart civil hospit daska random place three group acut group n chronic group n control group n mean age particip year mean bodi mass index male femal particip group group b treat decompress lumbar mobilis hot pack ten exercis therapi patient group c treat lumbar mobilis hot pack exercis therapi total durat treatment four week three session per week outcom measur baselin complet four week treatment visual analogu scale modifi oswestri disabl index straight leg rais inclinomet data analys use spss version one way anova kruskal walli test use compar mean across group conclud manual lumbar decompress decreas pain increas rang motion function group acut compar group b chronic group c control
D011843
T047;T037
36,280,987
descript case seri necrotis enterocol occurr aga khan univers hospit object studi determin frequenc outcom preterm infant diagnos necrotis enterocol nec case seri preterm infant enrol period month aga khan univers hospit karachi tertiari care hospit diagnosi stage done per bell stage criteria possibl confound filter analysi base form treatment symptom progress studi nec observ babi stage ii iii respect outcom analysi show among neonat diagnos nec discharg expir preval observ studi suggest major challeng neonatolog mortal outcom diagnos nec recommend earli diagnosi coupl prompt appropri treatment prevent measur reduc burden nec futur
D020345;D007232
T047
36,280,986
arteri blood gas analysi aid earli differenti diagnosi treatment primari secondari hypokalaem period paralysi studi aim examin chang electrolyt acid base status primari secondari hypokalaem period paralysi hypopp help earli differenti diagnosi hypopp total hypopp patient enrol relev data clinic record collect overal patient mean age year male patient respect diagnos primari hypopp thyrotox hypopp secondari hypopp discharg assess hypopp secondari condit hyperthyroid like develop acid base imbal p higher ph p hco level p baselin need higher dose potassium supplement serum potassium level return normal p longer time regain full muscl strength p compar primari thyrotox hypopp emerg arteri blood gas analysi may aid earli differenti diagnosi patient primari secondari hypopp
D020514
T047
36,280,985
effect sequenti approach posit releas subscapulari ola grimsbi techniqu shoulder extern rotat adhes sampl patient random assign two group b group posit releas subscapulari techniqu group particip propriocept neuromuscular facilit pnf hold relax anterior mobilis techniqu simultan appli group b particip data collect nusrat abdul rauf centr enabl faisal hospit faisalabad august novemb durat treatment four week three session per week main outcom measur numer pain rate scale nprs shoulder pain disabl index spadi shoulder extern rotat rang motion differ ola grimsbi group group b subscapulari releas group group statist signific pain disabl shoulder rang motion p valu higher mean valu ola grimsbi group studi conclud sequenti effect ola grimsbi techniqu better compar posit releas subscapulari term reduc pain improv shoulder extern rotat rang motion
D012785
T023;T030
36,280,984
associ candida speci novel sar cov biomark fungal premalign oral lesion oral fungal infect caus certain speci fungi among candida albican implic oral candidiasi correl multipl condit coronavirus diseas oral leukoplakia oral erythroplakia tenascin glycoprotein present site tissu injuri chronic inflamm tend express case malign matrix metalloproteinas belong famili zinc depend endopeptidas involv degrad extracellular matrix lead tissu invas metastasi current narrat review plan shed light fungal co infect coronavirus diseas molecular mechan matrix metalloproteinas tenascin involv pathogenesi fungus associ oral leukoplakia oral erythroplakia
D000086382;D011230
T047;T191;T067
36,280,983
pulmonari physic therapi techniqu manag covid patient systemat review review studi report pulmonari physic therapi techniqu manag coronavirus diseas patient
D000086382
T047;T067
36,280,982
bone marrow biopsi effect diagnost modal pancytopenia among paediatr adult popul determin aetiolog pancytopenia base bone trephin biopsi among paediatr adult patient
D010198;D000741
T047
36,280,981
proteinuria asymptomat sibl children steroid resist nephrot syndrom screen use urinari dipstick screen asymptomat sibl steroid resist nephrot syndrom patient proteinuria use urinari dipstick method determin involv sibl famili like genet caus steroid resist nephrot syndrom
D009404
T047
36,280,980
impact age gender post infect post vaccin status antibodi respons covid patient evalu sever acut respiratori syndrom coronavirus spike protein antibodi coronavirus diseas post infect post vaccin individu
D000917;D000086382
T047;T067;T038
36,280,979
second wave covid diseas haemodialysi patient experi dialysi center pakistan evalu characterist outcom second wave coronavirus diseas haemodialysi patient
D000086382;D013921
T047;T067
36,280,978
safeti advers effect inact sar cov vaccin coronavac health care profession assess advers effect post vaccin healthcar profession first vaccin group coronavirus diseas
D000086382;D000086663;D006282
T200;T047;T097;T067
36,280,977
relationship muscular impair psycholog health lower extrem function patient transtibi amput determin relationship muscular impair psycholog health lower extrem function patient transtibi amput
D000671;D000674
T061;T101
36,280,976
assess function abil anthropometr physiolog paramet six minut walk test healthi children assess function abil vital young children use six minut walk test
D016138;D000203
T056;T169;T080
36,280,975
vitamin level effect covid posit covid relat mortal retrospect studi explor possibl relationship vitamin coronavirus diseas urban popul known relat low vitamin level
D000086382;D014808
T047;T067
36,280,974
descript studi frequenc short term complic late preterm neonat tertiari care hospit rawalpindi determin frequenc short term complic late preterm neonat tertiari care set
D012127;D047928
T047;T046
36,280,973
self assess activ learn critic think problem base learn exploratori studi assess whether problem base learn enhanc student percept activ learn critic think skill time valid self assess scale regard activ learn critic think local context
D018794;D012647
T065;T055;T041
36,280,972
nicotin depend intent quit among electron convent dual cigarett user karachi compar nicotin depend intent quit among differ type smoker
D014029;D066300;D016540;D062789
T073;T109;T055;T131;T048
36,280,971
machin vision base statist textur analysi techniqu character liver tissu use ct imag character human liver tissu demonstr abil machin vision propos new auto generat report base textur analysi may work co occurr matrix statist
D000465;D014057
T060;T170
36,280,970
reliabl modifi modifi schober test assess lumbar rang motion determin intra rater reliabl modifi modifi schober test measur lumbar flexion extens patient lumbar radiculopathi
D008159;D011843
T023;T037;T047
36,280,969
posit predict valu birad iv lesion mammogram detect breast carcinoma determin posit predict valu breast imag report data system categori iv lesion evalu interobserv agreement among radiologist interpret subcategori
D016217;D001943
T060;T191