Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,280,968	associ chest xray cxr find outcom covid patient investig chest radiographi find suspect coronavirus diseas patient tertiari care set	D000086382	T047;T067
36,280,967	effect vibrat induc electr tooth brush amount canin retract cross section studi done univers lahor evalu effect local vibrat amount canin retract st premolar extract assess anchorag loss	D052280	T061
36,280,966	transloc acut precursor b cell lymphoblast leukaemia paediatr patient pakistani popul determin impact transloc paediatr patient diagnos precursor b cell acut lymphoblast leukaemia	D015452;D054198	T191
36,280,965	medic imag problem base learn impact student cross section studi investig medic student perform percept toward differ multimedia medic imag tool	D004504;D013337	T065;T097
36,280,964	big five inventori version two minut person measur tool urdu translat urdu valid big five inventori	D014177;D014175	T170;T057
36,280,963	urinari tract infect complic kidney stone correl guy stone score ascertain exist connect guy stone score infecti complic percutan nephrolitholapaxi	D007669;D014552;D009403	T061;T047
36,280,962	analys trend patient safeti non technic skill among postgradu traine modifi survey tool analys practic patient safeti non technic skill among postgradu traine establish util organis teach programm regard determin utilis differ teach mode	D061214;D002983	T058;T080
36,280,961	automat negat thought contribut factor adult convers disord see automat negat thought contribut convers disord adult	D004644;D003291	T041;T048
36,280,960	stutter relat psychosoci predictor impact stutter investig psychosoci factor impact person stutter problem	D013342	T184;T047;T048
36,280,959	relationship preoper smoke cessat anxieti postop anxieti pain prospect clinic trial univers hospit east turkey particip reveal relationship smoke cessat surgeri pre post oper anxieti pain among chronic smoker	D016540	T055
36,280,958	efficaci singl dose dermatolog tacrolimus ointment treatment vernal keratoconjunct assess safeti dermatolog tacrolimus ointment use topic efficaci treatment vernal keratoconvinctivti	D016559;D003233	T121;T047;T109
36,280,957	risk hypertens incid hospit cardiac arrest analys effect hypertens occurr hospit cardiac arrest find whether effect depend use anti hypertens drug	D058687;D016887;D004632;D006973	T061;T093;T058;T046;T047
36,280,946	technolog advanc stroke rehabilit earli coordin multidisciplinari rehabilit play major part motor recoveri stroke convent stroke rehabilit primarili includ physic therapi occup therapi speech therapi howev convent method mani stroke survivor still residu function disabl impair abil perform activ daili live could attribut insuffici therapi dose low engag motiv patient lack object feedback achiev signific improv function various technolog base stroke rehabilit intervent develop last decad shown promis result improv stroke patient function mobil independ use technolog promot repetit task specif train activ engag patient integr construct concurr feedback accur measur function improv review summar import technolog advanc stroke rehabilit includ exergam telerehabilit robot assist system virtual augment realiti wearabl sensor smartphon applic	D000071939;D020521	T061;T047
36,280,944	role diffus tensor imag brain tumour resect diffus tensor imag dti advanc imag techniqu help establish topograph anatom relationship tumour surround white matter tract intra oper use neuro navig help minim injuri function brain parenchyma decreas risk post oper neurolog deficit review assess efficaci dti brain tumour resect	D056324;D001932	T060;T191
36,280,943	strategi appetit suppress key player manag diabet obes peopl diabet obes advis curtail calori intak order improv glycaem control reduc weight howev mani patient complain inabl manag appetit therebi find difficult control calori intak dysregul appetit lead glycaem swing creat challeng metabol manag moreov short term non structur method suppress appetit often caus rebound excess food intak even overshoot baselin intak articl share non pharmacolog heurist hack help suppress optim appetit use day day clinic practic	D001066;D003920	T039;T040;T047
36,280,942	osteoporosi diabet dual pandem bone health import neglect aspect diabet care peopl type diabet known lower bone miner densiti bmd put greater risk osteoporosi fractur bmd type diabet often mislead multipl factor oper increas risk fall fractur articl provid overview osteoporosi diabet propos lemon mnemon understand multifacet aspect bone care	D003924;D050723;D010024;D058866	T047;T037
36,280,941	pruritus microvascular equival diabet pruriti common symptom mani system cutan local diseas diabet mellitus common syndrom multipl long term complic includ diabet pain neuropathi involv small fibr neuron diabet neuropathi recogn main pathophysiolog c fibr mediat sensat pain pruritus may belong differ neuron circuit evid cross talk therefor posit pruritus may symptom diabet neuropathi view equival microvascular diseas accompani clinic signific therapeut implic	D003929;D003920	T047
36,280,940	sexual behaviour chang seroneg limbic enceph due involv left amygdala limbic enceph le rare caus enceph general present neuropsychiatr manifest memori deficit seizur movement disord case year old femal patient le involv left amygdala present patient admit emerg depart complaint unconsci seizur paraneoplast limbic marker negat case diagnos seroneg le three four month diagnosi observ sexual prefer chang femal sex report publish far concern case le associ chang sexual behaviour patient treat intraven methylprednisolon ivp tripl antiepilept therapi treatment chang sexual behaviour return previous state	D020363	T047
36,280,939	function pituitari gonadotroph adenoma male patient case report pituitari gonadotroph adenoma common rare secret biolog activ lutein hormon lh follicl stimul hormon fsh case studi report high sex hormon testosteroneestrogen presenc high normal lh fsh report two case consent present visual disturb headach tertiari care hospit aga khan univers hospit karachi pakistan brain imag reveal pituitari macroadenoma workup consist pituitari gonadotroph adenoma high fsh case normal lhfsh case elev serum testosteron case transsphenoid resect perform tissu sampl histopatholog confirm pituitari adenoma postop improv hormon profil observ along resolut visual disturb headach thus function gonadotroph adenoma consid presenc elev testosteroneestrogen normal elev follicl stimul hormon fsh lutein hormon lh earli diagnosi lead better outcom	D010911;D052681;D000236	T191;T025
36,280,938	rare seen bilater posterior shoulder fractur disloc simultan bilater hemiarthroplasti posterior shoulder disloc rare condit bilater posterior shoulder fractur extrem rare disloc fractur bilater posterior shoulder observ often epilept seizur disloc posterior shoulder fractur rare clinician sometim experi difficulti diagnos time although diagnos treat earli base proper shoulder examin accur radiolog imageri treatment posterior shoulder disloc close reduct perform earli stage method osteosynthesi open reduct arthroplasti frequent use procedur delay stage studi shown first time literatur rare case disloc bilater posterior shoulder fractur epilept seizur year old patient good clinic function result follow simultan hemiarthroplasti treatment	D062785;D012784;D012783;D004827	T061;T047;T033;T037
36,280,937	post caesarean necrot soft tissu infect lead matern death case report necrot soft tissu infect lethal lead sepsi multi organ failur death describ case report us within hour caesarean section acut abdomin pain tachycardia tachypnoea local examin reveal larg area necrot subcutan tissu involv caesarean section scar immedi debrid carri repeat twice initi procedur could surviv	D018461;D063130;D018805	T047;T040;T046
36,280,936	covid associ anterior uveiti post covid acut anterior uveiti covid outbreak wuhan st decemb soon becam pandem ocular manifest post covid patient wide report anterior uveiti common form intraocular inflamm observ daili basi ophthalmologist diagnosi aau relat simpl identif etiolog difficult specif covid post covid aau report pakistan yet patient given case investig thorough possibl caus aau identifi patient manag uveiti	D000086382;D014606;D014605	T047;T067
36,280,935	extensor lag patient total knee arthroplasti without pre oper rehabilit regim short report total knee arthroplasti gain popular individu advanc stage knee osteoarthr among afford econom class aim studi assess effect preoper rehabilit manag post oper quadricep lag studi design non randomis clinic studi conduct januari march ghurki trust teach hospit lahor pakistan non probabl conveni sampl techniqu appli collect data patient tka data collect self design questionnair goniometr rang knee extens use main outcom independ sampl test appli assess differ group mean age patient year mean score extensor lag pre oper rehabilit regim without regim p valu valu studi show correl increas post oper extensor lag pre oper rehabilit regim	D019645;D020370	T061;T047
36,280,934	effect cervic stabilis exercis respiratori strength chronic neck pain patient forward head postur object studi determin effect cervic stabilis exercis respiratori strength chronic neck pain patient forward head postur studi conduct august februari jinnah hospit lahor patient fulfil elig criteria random assign two group experiment group control group baselin measur taken numer pain rate scale neck disabl index craniovertebr angl singl breath count spirometri measur retaken complet fourth week result signific p treatment group post intervent result reveal signific differ group p experiment group show improv four week cervic stabilis isometr exercis effect manag pain forward head postur neck disabl respiratori strength compar four week isometr exercis programm alon	D019547;D059350	T184;T047
36,280,933	paediatr penil percept score ppps hypospadia repaird present cross section studi sought evalu paediatr penil percept score ppps tool assess parent percept hypospadia repair children patient enrol studi median age year proxim hypospadia distal hypospadia hypospadia repair parentsguardian interview meatus glan skin general appear use standardis questionnair report penil appear penil percept overal median ppps score iqr signific differ penil percept score type hypospadia relationship person interview child mother father children age studi reveal penil percept score ppps valuabl tool use assess parent penil percept regard child penil appear note overal high satisfact hypospadia repair	D007021	T019
36,280,932	comparison effect haloperidol quetiapin acut manic episod studi conduct compar respons rate quetiapin haloperidol patient acut manic episod total patient acut episod mania baselin young mania rate scale ymrs includ random alloc either quetiapin group haloperidol group b patient assess baselin ymrs administ start follow visit six week comparison respons rate reduct ymrs statist signific two group vs p six week acut manic episod quetiapin haloperidol emerg equal effect pharmacolog strategi treatment bipolar mania quetiapin may use altern convent antipsychot haloperidol use replac quetiapin well low cost	D014150;D000087122	T033;T121;T039;T048
36,280,931	transposit basil vein vascular access haemodialysi experi tertiari care hospit basil vein transposit bvt prefer perman haemodialysi access due better patenc lower infect rate compar synthet graft outcom bvt case perform shifa intern hospit islamabad march june ambispect investig primari patenc fistula assess immedi surgeri hour day week month total patient includ studi male femal total patient underw one stage bvt underw two stage bvt one hundr thirti five procedur success surviv case fail mean basil vein diamet mm overal patient bleed fistula thrombos steal syndrom patient develop pseudo aneurysm conclud bvt feasibl techniqu good patenc rate especi patient multipl forearm avf surgeri	D001166	T061
36,280,930	fungal isol wound sampl submit cultur tertiari care hospit laboratori fungal wound infect increas worldwid aim retrospect studi conduct aga khan univers laboratori karachi pakistan determin frequenc fungal isol wound specimen data wound sampl receiv cultur countri septemb octob review sampl process bacteri cultur addit inocul sabouraud dextros medium demograph inform medic histori inform type wound collect total case includ cultur posit case yield fungi burn blast wound highest proport fungal isol ie candida speci common fungi n follow fusarium speci n studi report alarm rate fungal wound infect fungal necrotis wound infect high morbid mortal therefor import accur diagnos treat infect local set	D014946;D009181	T047;T046
36,280,929	develop banff classif identifi renal allograft reject narrat review nephrologist renal pathologist nephrologist transplant surgeon held meet banff canada develop classif scheme standardis intern classif renal allograft biopsi call banff classif follow first meet meet held usual everi two year revis classif light new evid techniqu latest print consensus meet pittsburgh unit state america sever articl publish last year creat ambigu nephrologist made thing challeng expert pathologist current perspect review plan make easi clear beginn practition banff classif evolv sinc incept	D016030	T061
36,280,928	long term prognosi culott versus differ crush strategi manag unprotect left main bifurc coronari lesion meta analysi assess long term clinic effect culott differ crush techniqu treatment unprotect left main bifurc coronari lesion determin best percutan coronari intervent strategi	D003324	T047
36,280,927	audit contrast extravas patient undergo contrast enhanc cts radiolog depart tertiari care hospit pakistan audit radiolog depart health facil focus contrast extravas manag pre post implement standard protocol	D005119;D011871	T046;T091;T037
36,280,926	effect util time non oper room anaesthesia servic aga khan univers hospit karachi prospect qualiti improv audit identifi servic qualiti gap review oper room anaesthesia servic tertiari care hospit	D058996;D000758	T061;T057
36,280,925	epidemiolog complic snakebit rural area badin thar sind pakistan identifi popul risk snakebit peak season site bite	D012909	T037
36,280,924	pain experienc patient epidur insert use gaug versus gaug epidur needl compar intens insert site pain epidur catheteris gaug needl gaug needl various time point number attempt taken locat epidur space use either needl	D004824;D000775	T061;T030
36,280,923	avail use autom extern defibril karachi pakistan cross section studi assess avail use autom extern defibril various public privat establish assess knowledg attitud practic relat use	D058687;D016887	T061;T046
36,280,922	correl serum malondialdehyd level preval cardiovascular diseas haemodialysi treat patient investig role serum malondialdehyd diagnost biomark free radic product cardiovascular diseas patient treat mainten haemodialysi	D059168;D002318	T201;T047
36,280,921	patient visit gastroenterolog clinic avoid give honest histori covid relat symptom pre clinic triag assess discrep term histori relat coronavirus diseas symptom given pre clinic triag doctor attend patient gastroenterolog clinic	D000086382;D005762	T047;T091;T067
36,280,920	fear covid stress univers student mediat role cyberchondria moder role creativ cope social support find moder role social support creativ cope mediat role cyberchondria relationship fear coronavirus diseas stress univers student	D000086382	T047;T067
36,280,919	associ matern nutrit status neonat anthropometri cross section studi identifi associ matern nutrit status neonat anthropometri	D009752;D014527	T033;T123;T114;T109
36,280,918	colostomi ileostomi care nurs educ effect synchron asynchron compar effect synchron asynchron train academ achiev e learn attitud nurs student train colostomi ileostomi care	D004506;D013338	T065;T097
36,280,917	preval vocal tract discomfort patient voic disord analys preval vocal tract discomfort patient voic disord	D014832	T033;T047
36,280,916	common caus hear impair among children less year age district bahawalpur punjab pakistan find common caus hear loss among young children compar caus along gender line	D010034;D034381;D010033	T033;T047
36,280,915	preval factor associ undernutrit among month children tehsil battagram pakistan find preval associ factor undernutrit semi rural set	D019282;D015362;D044342	T047
36,280,914	frequenc median nerv tight associ upper limb function among smartphon user public sector univers karachi determin median nerv tight smartphon user compar upper limb function without median nerv tight	D018737;D008475	T081;T023;T040
36,280,913	use system steroid pulmonari exacerb children adolesc cystic fibrosi determin role system steroid cystic fibrosi patient effect pulmonari exacerb children adolesc	D003550	T047
36,280,912	determin health promot behaviour self rate health life satisfact loneli among older person determin relationship health promot behaviour loneli life satisfact self rate health among elder	D008132;D006233	T033;T101
36,280,911	impact adipos paramet peak expiratori flow rate healthi young adult bahria univers medic dental colleg karachi cross section studi explor associ various adipos paramet young adult	D050154;D009765	T047;T032
36,280,910	correl prognosi cost effect comput tomographi hospit cardiac arrest patient return spontan circul emerg depart assess preval comput tomographi applic hospit cardiac arrest case emerg depart process contribut chang patient manag effect hospit discharg cost effect	D058687;D016887;D004632	T061;T058;T046;T093
36,280,909	translat valid stroke impact scale urdu pakistan translat valid urdu version stroke impact scale pakistani societi	D014177;D020521	T047;T170
36,280,908	outcom emerg vascular surgeri perform general surgeon experi univers hospit pakistan substitut vascular surgeon measur outcom emerg vascular surgeri perform general surgeon identifi prevent caus mortal	D014656;D066231	T061;T097
36,280,907	clinic spectrum sarcoidosi patient tertiari care hospit pakistan ten year follow studi identifi local pattern manifest organ involv lung diagnost tool treatment regimen relat patient sarcoidosi	D012507;D017563	T047
36,280,906	adapt preserv sturdi journey creat new normal phenomenolog insight factor affect medic resid journey consult practic explor factor promot hamper medic resid journey resid induct role adapt consult practic	D007396	T065;T097
36,280,905	effect light emit diod led cure mode depth cure doc bulkfil composit resin invitro studi evalu depth cure smart dentin replac bulkfil composit resin polymer constant puls ramp light emit diod cure mode	D003188;D011138	T122;T109
36,280,904	clinic outcom accord intent acut pesticid poison south korea retrospect observ studi investig intent pesticid intak could differ clinic outcom compar unintent poison whether acut alcohol consumpt correl intent poison	D010575;D011041	T131;T037
36,280,889	measur address stall develop health law educ chines univers health law educ import part global health educ benefici medic law school field help lawyer polici maker develop career equip tradit health profession doctor nurs basic knowledg health law howev unlik western univers health law educ china still infant stage lack systemat pedagog approach among institut higher educ china consid advanc field health law educ studi systemat review status health law educ institut higher learn china suggest way make pedagog approach consist systemat review reveal major law school medic school develop subject health law educ china lack consensus aim scope mode method health law educ first problem chines univers unabl agre classifi subject health law anoth set problem relat institut univers lack qualifi health law faculti also reli relat uninspir teach materi lead ineffect generic pedagog approach medic law school problem leav futur lawyer futur doctor nurs unclear choic health law studi graduat level ultim career develop therefor propos four preliminari solut continu develop new interdisciplinari subject health law educ chines univers clear classifi subject health law equip health law field profession textbook enact joint degre program medic school law school establish health law research center either law school medic school	D012577;D004500	T065;T073;T093
36,280,888	signific variat perform dna methyl predictor across data preprocess normal strategi dna methyl dnam base predictor hold great promis serv clinic tool health intervent diseas manag algorithm often high predict accuraci consist perform remain determin therefor conduct systemat evalu across differ dnam data preprocess normal strategi assess analyt strategi affect consist dnam base predictor	D019175	T044
36,280,884	hypox induc rest ventilatori circulatori respons multistep hypoxia relat declin peak aerob capac hypoxia sever factor shown contribut hypox induc declin aerob capac present studi investig effect rest hypox ventilatori cardiac respons hvr hcr hypox induc declin peak oxygen uptak formula see text peak	D010101;D000860	T201;T184;T033;T046
36,280,881	earli embryon lethal complex associ plp nubpl mutant mice variant mitochondri complex assembl factor nubpl associ rare caus complex defici mitochondri diseas patient affect complex defici harbor homozyg nubpl variant typic neurolog problem includ seizur intellectu disabl ataxia associ cerebellar hypoplasia thus far case report worldwid treatment avail rare diseas	D051844;D024101	T123;T116
36,280,878	pangenom wheat pathogen pyrenophora tritici repenti reveal novel transposon associ necrotroph effector toxa toxb fungal plant pathogen genom rearrang follow select pressur adapt trait facilit co evolutionari arm race host pathogen pyrenophora tritici repenti ptr emerg recent foliar pathogen wheat worldwid popul consist isol vari abil produc combin differ necrotroph effector effector play vital role diseas develop sequenc genom global collect isol ptr gain insight gene content genom rearrang	D009183;D001203	T131;T004;T109
36,280,877	epidemiolog dengu saarc territori systemat review meta analysi dengu one common arbovir infect public health problem south east asia aim systemat review meta analysi evalu preval distribut dengu saarc south asian associ region cooper countri	D003716;D003715;D013921	T005;T047
36,280,876	depress primari care role evid base guidelin cross section data primari care physician germani depress common mental health burden worldwid primari care physician pcps play key role care provis peopl depress first object present studi examin health care situat depress primari care focus cooper pcps mental health specialist second aim examin role german guidelin unipolar depress primari care provis	D058007	T097
36,280,874	clinic implic circul tumor dna predict outcom diffus larg b cell lymphoma patient receiv first line therapi circul tumor dna ctdna proven promis tumor specif biomark solid tumor clinic util risk stratif earli predict relaps diffus larg b cell lymphoma dlbcl well explor	D000074141;D016403	T191;T114
36,280,873	pro thrombot chang associ exposur ambient ultrafin particl patient chronic obstruct pulmonari diseas role lipid peroxid system inflamm exposur particul matter air pollut associ increas risk cardiovascular mortal patient chronic obstruct pulmonari diseas copd under mechan yet understood enhanc platelet pro thrombot activ copd patient may explain increas cardiovascular risk aim explor whether short term exposur ambient particul matter associ pro thrombot chang adult without copd investig under biolog mechan longitudin panel studi serum concentr thromboxan tx b measur reflect platelet pro thrombot activ lipoxygenas mediat lipid peroxid product hydroxyeicosatetraeno acid hete inflammatori biomark interleukin il monocyt chemoattract protein mcp tumour necrosi factor alpha tnf macrophag inflammatori protein mip measur potenti mediat determin particl associ pro thrombot chang	D000393;D000397;D029424	T131;T047;T069;T080
36,280,870	bifunct anti pd ltgf rii agent shr advanc solid tumor dose escal dose expans clinic expans phase trial dual inhibit pd pd l tgf pathway ration therapeut strategi malign shr new bifunct fusion protein compos monoclon antibodi pd l fuse extracellular domain tgf receptor ii first human trial aim assess shr pretreat advanc solid tumor find popul could benefit shr	D013274	T191
36,280,868	like pathogen pold variant associ mandibular hypoplasia deaf progeroid featur lipodystrophi syndrom chines patient mandibular hypoplasia deaf progeroid featur lipodystrophi syndrom mdpl omim rare autosom domin disord report case worldwid herein describ clinic featur under molecular etiolog mdpl syndrom year old chines patient	D003638;D008060	T033;T184;T047
36,280,866	narrat review centuri respiratori pandem spanish flu covid impact nanotechnolog covid diagnosi immun system boost rise high lethal sever acut respiratori syndrom sar corona virus covid remind us histori pandem happen last centuri spanish flu stay current centuri includ sever acut respiratori syndrom sar middl east respiratori syndrom mer corona virus covid review report newest find data origin pandem respiratori viral diseas reservoir transmiss mode analyz viral adapt need host switch determin pathogen causat factor pandem virus symptom clinic manifest conclud host factor associ pandem morbid mortal immun respons immunopatholog age effect pandem pregnanc addit focus burden covid non pharmaceut intervent quarantin mass gather facemask hygien medic intervent antivir therapi vaccin final investig nanotechnolog covid analysi immun system boost nanoparticl nps antimicrobi nps antivir immun cytokin review present insight use nanomateri treat covid improv bioavail abus drug diminish toxic improv perform	D000086382;D064149;D065207	T047;T005;T067
36,280,865	radiograph comput tomograph evalu supin sesamoid bone dog present studi evalu frequenc supin sesamoid bone ssb radiographi comput tomographi ct interobserv agreement evalu detect ssbs method correl exist ssbs elbow diseas ed assess purpos radiograph ct scan dog score observ	D012716	T023
36,280,863	relationship bodi mass index frailti caus mortal among middl age older adult parallel growth age obes popul preval metabol diseas rise bodi mass index bmi relat frailti mortal across frailti level controversi examin associ high bmi frailti mortal explor effect percent bodi fat associ	D000073496	T033;T184;T046
36,280,861	hospit initi pcsk inhibitor short term lipid control patient acut myocardi infarct proprotein convertas subtilisinkexin type pcsk inhibitor shown improv cardiovascular outcom ad convent statin therapi studi aim investig efficaci safeti hospit initi pcsk inhibitor among patient acut myocardi infarct ami base real world experi	D000924;D019161;D009203	T121;T047;T109
36,280,859	toe grip strength declin earlier hand grip strength knee extens strength communiti dwell older men cross section studi aim studi examin age relat chang toe grip strength differ hand grip strength knee extens strength use cross section data	D018737;D057187	T081;T056;T040
36,280,858	low abund popul distinguish microbiom perform plant cell wall deconstruct plant cell wall interwoven structur recalcitr degrad nativ adapt microbiom particular effect plant cell wall deconstruct although understand biolog cell wall deconstruct obtain isol cultiv microbiom break cell wall emerg new sourc biotechnolog relev microb enzym microbiom provid uniqu resourc identifi key interact function microbi group guid design special synthet microbi communiti	D064307	T001;T032;T028
36,280,857	sex specif exposur sex combin outcom two sampl mendelian random may mislead causal infer great interest read recent articl age menarch age natur menopaus risk rheumatoid arthriti mendelian random studi zhu et al great appreci work conduct author methodolog issu need reconsid first gender descript sampl age first birth studi wrong accord origin genom wide associ studi second studi exploit sex specif snps age menarch aam age natur menopaus anm sex combin effect snps rheumatoid arthriti ra possibl lead evid causat aam anm ra suggest author add possibl bias due issu limit problem mention recommend solut make articl perfect	D008572;D001172	T047;T040
36,280,856	cornin protect cerebr ischemiareperfus injuri prevent autophagi via pikaktmtor pathway ischemia stroke lead caus disabl consequ vascular occlus purpos studi investig effect cornin isol fruit verbena officinali l astrocyt autophagi induc cerebr ischemiareperfus cir injuri vitro vivo potenti mechan	D002545;D018696;D015427;D057889	T121;T109;T037;T047;T046;T169
36,280,855	postop weak anesthet associ rhabdomyolysi pediatr patient case report review literatur anesthesia associ rhabdomyolysi rare complic surgeri caus postop myalgia weak potenti renal failur manag prompt predispos condit may lead complic includ muscular dystrophi myopathi	D008305;D012206;D000777	T121;T039;T046;T037
36,280,854	deciph chloramphenicol biotransform mechan microbi interact via integr multi omic cultiv depend approach wide use broad spectrum antibiot chloramphenicol prone releas environ thus result disturb ecosystem stabil well emerg antibiot resist gene microb play vital role decomposit chloramphenicol environ biotransform process especi depend synergist interact metabolit exchang among microb herein comprehens chloramphenicol biotransform pathway key metabol enzym interspeci interact activ sludg enrich consortium elucid use integr multi omic cultiv base approach	D004785;D020578	T131;T007
36,280,853	crop manag shape divers activ dna rna virus rhizospher rhizospher hotspot microbi activ contribut ecosystem servic includ plant health biogeochem cycl activ microbi virus influenc plant microb interact rhizospher remain undetermin given impact virus ecolog evolut host communiti determin soil virus influenc microbiom dynam crucial build holist understand rhizospher function	D064307;D012328;D001435;D029688	T032;T168;T002;T005;T028;T001
36,280,852	clinic impact cardiac magnet reson patient suspect coronari arteri diseas associ chronic kidney diseas aquamarin ckd studi studi protocol random control trial although screen coronari arteri diseas cad use comput tomographi coronari angiographi patient stabl chest pain report benefici patient chronic kidney diseas ckd might limit benefit due complic contrast agent nephropathi decreas diagnost accuraci result coronari arteri calcif cardiac magnet reson cmr emerg novel imag modal detect coronari stenosi high risk coronari plaqu without contrast media affect coronari arteri calcif howev clinic use technolog robust evalu	D003324;D051436	T047
36,280,851	cost effect folic acid therapi primari prevent stroke patient hypertens hypertens patient without histori stroke myocardi infarct mi china stroke primari prevent trial csppt demonstr treatment enalapril folic acid reduc risk primari stroke compar enalapril alon whether folic acid therapi afford benefici treatment strategi primari prevent stroke hypertens patient chines healthcar sector perspect thorough explor	D006973;D020521	T047
36,280,850	effect mosquito rest site temperatur estim pathogen develop rate near natur habitat germani environment temperatur key driver transmiss risk mosquito born pathogen epidemiolog model usual relat temperatur data standard weather station data may captur relev scale mosquito experi environment temperatur mosquito assum spend lifetim rest site analys mosquito rest site pattern associ temperatur depend rest site type rest site height surround land use	D009033;D003465;D000852;D000330	T204
36,280,849	methotrex improv endotheli function earli rheumatoid arthriti patient month treatment endotheli dysfunct contribut increas cardiovascular cv diseas rheumatoid arthriti ra angiogen cell tang key regul vascular function via interact endotheli progenitor cell epc methotrex mtx associ reduc cv diseas risk effect endotheli homeostasi poor explor investig mtx effect endotheli homeostasi earli treatment nave ra patient	D018501;D001172	T121;T047
36,280,848	live liver donor underestim surgic outcom impact health relat qualiti life donat descript cross section studi south korea number live donor liver transplant live liver donor llds undergo surgeri postop recoveri process altruist purpos studi explor llds unmet expect surgic outcom examin impact donor health relat qualiti life hrqol	D019520;D016031	T061;T098
36,280,846	deleg patient relat task alli health assist time motion studi alli health assist aha support staff complet patient non patient relat task deleg alli health profession deleg patient relat task aha benefit patient alli health profession howev unclear whether aha workforc utilis optim provis patient care purpos studi determin proport time aha spend patient relat task work day differ across level aha experi clinic set profess deleg task	D000488;D032022;D016390	T077;T091;T097
36,280,845	immun relat histolog phenotyp pretreat tumour biopsi predict efficaci neoadjuv anti pd treatment squamous lung cancer although neoadjuv anti pd immunotherapi shown good efficaci non small cell lung cancer nsclc patient still lack effect predict marker aim develop pretreat histolog score system predict efficaci neoadjuv immunotherapi	D002289;D002294;D008175	T191
36,280,843	one plus one alway equal two structur differ nesfatin nesfatin nesfatin produc reaction n terminus human nucleobindin undergo proteolyt process date nucleobindin andor nesfatin shown act peptid hormon hand purpos nesfatin remain unknown sinc nucleobindin nesfatin thought impact control wide rang physiolog process includ energi homeostasi neurodegen process carcinogenesi ligandsinteract deserv special studi attent howev report molecular properti proteolyt product human nucleobindin literatur henc studi aim analyz effect zn ii ca ii human nesfatin structur herein report human nesfatin member intrins disord protein famili indic circular dichroism analyt ultracentrifug experi contrast found human nesfatin nesfatin structur globular intrins disord region zn ii treatment observ concentr depend structur compact intrins disord nesfatin propens oligomer well destabil nesfatin nesfatin furthermor dissoci constant zn ii bind nesfatin nesfatin nesfatin also report moreov structur distinct nesfatin seem interdepend link togeth indic observ molecular properti nesfatin turn simpl sum properti exhibit former peptid thus herein shed new light molecular behavior human nesfatin might help elucid complex function peptid video abstract	D064267;D036361	T125;T123;T116
36,280,842	metabolom profil prostat cancer specif surviv among finnish men abnorm metabol perturb metabol pathway play signific role develop progress prostat cancer howev comprehens metabolom analys human data lack need elucid interrelationship	D019207;D011471	T121;T191;T127;T109
36,280,841	loss npm express potenti immunohistochem marker malign periton mesothelioma singl center studi case malign periton mesothelioma mpm rare malign tumor high mortal rate extrem poor prognosi depth patholog analysi essenti assess tumor biolog behavior explor potenti therapeut target mpm nucleoplasmin npm molecular chaperon bind histon may play key role develop progress tumor studi aim analyz correl express level npm main clinicopatholog characterist prognosi mpm	D008175;D000086002;D056489;D010534;D010997;D019043	T123;T191;T116
36,280,840	sex specif chang triglycerid profil liver cirrhosi hepat c virus infect hepat c virus hcv infect associ serum lipid abnorm part normal follow direct act antivir daa therapi associ serum triglycerid tgs viral genotyp marker liver diseas sever evalu patient chronic hcv method studi includ serum patient chronic hcv tgs quantifi flow inject analysi fourier transform mass spectrometri laboratori valu noninvas score liver fibrosi assess determin nonparametr kruskalw test one way anova multipl linear regress student test use appropri p valu adjust multipl comparison	D019698;D006526	T047
36,280,839	efficaci metformin therapi patient cancer meta analysi randomis control trial investig whether metformin monotherapi adjunct therapi improv prognosi patient type cancer compar non metformin user age	D008687;D009369	T121;T191;T109
36,280,838	cchcr astrin interact promot centriol duplic recruit cep centrosom one import non membran organell regul microtubul organ progress cell mitosi coil coil alpha helic rod protein cchcr also known hcr gene consid psoriasi suscept gene protein suggest local p bodi centrosom mammalian cell howev exact cellular function hcr potenti regulatori role centrosom remain unexplor	D002502;D018797	T026;T123;T116
36,280,836	role continu medic educ program promot iranian nurs compet toward non communic diseas qualit content analysi studi continu medic educ essenti nurs provid qualiti patient care upgrad profession skill compet need continu medic educ cme becom appar face advanc medic scienc ever chang healthcar system nurs vital role improv health care therefor imper explor nurs experi cme cours extent program effect	D004502;D000073296	T065;T047
36,280,835	associ number remain teeth disabl free life expect impact oral self care older japanes adult prospect cohort studi tooth loss report associ shorter disabl free life expect dfle howev studi explor whether oral self care offset reduct dfle present studi aim assess associ oral self care dfle older individu tooth loss	D016388;D006233	T020;T101
36,280,834	non invas near infrar spectroscopi assess spinal neurovascular respons patient transvers myeliti case report transvers myeliti tm character acut develop motor sensori autonom dysfunct due horizont diffus inflamm one segment spinal cord absenc compress lesion well known inflamm process induc demyelin result neurolog dysfunct	D009188;D001342	T047
36,280,833	trend mortal alcohol opioid combin alcohol opioid poison sex educ attain race ethnic unit state ongo opioid epidem increas alcohol relat mortal key public health concern usa well document inequ degre group low high educ affect studi aim quantifi dispar time educ racial ethnic group sex specif mortal rate opioid alcohol combin alcohol opioid poison usa	D005006;D000701	T121;T098;T109;T131;T102
36,280,832	implement general practition general physician econsult servic econsult australia respons lengthi wait time specialist outpati appoint electron consult econsult servic develop global provid asynchron secur time communic general practition gp specialist studi aim track adopt queensland econsult servic two australian primari health network western queensland brisban south understand key barrier enabl adopt inform modif implement strategi method theori inform mix method evalu assess implement juli march adopt implement activ prospect record bespok track spreadsheet implement activ code expert recommend implement chang eric strategi semi structur interview gps stakehold inform consolid framework implement research cfir conduct understand determin implement result practic invit take part econsult servic enrol gps consent sent least one request advic rfa econsult total rfa sent implement predomin guid eight strategi qualit interview conduct gps stakehold ruralremot region femal two sole practition interviewe felt econsult servic support outpati appoint avoid provid effici time access specialist support gps patient barrier identifi use econsult relat digit infrastructur compet prioriti keep servic front mind key enabl identifi relat advantag econsult option patient benefit covd facilit use digit technolog	D058005;D012017	T058;T170;T097
36,280,830	pattern treatment outcom rectal cancer concurr locoregion recurr distant metastas total mesorect excis studi pattern treatment outcom rectal cancer rc concurr locoregion recurr lr distant metastasi dm total mesorect excis tme identifi patient diseas treatment relat factor associ differ prognosi concurr lr dm	D009364;D012004	T191
36,280,829	rbck endogen inhibitor tripl negat breast cancer via hippoyap axi tripl negat breast cancer tnbc one lethal breast cancer subtyp due lack effect therapeut target chemotherapi still main medic treatment tnbc patient thus import necessari find new therapeut target tnbc recent genom studi implic hippo yap signal activ tnbc manifest play key role tnbc carcinogenesi cancer progress rbck first identifi import compon linear ubiquitin assembl complex lubac facilit nfkb signal immun respons studi show rbck also facilit lumin type breast cancer growth endocrin resist via tran activ estrogen receptor alpha	D064726	T191
36,280,828	transcriptom metabolom analys reveal girdl promot leaf color express acer rubrum l acer rubrum l red mapl popular tree attract color leav strong physiolog adapt high ornament valu chang leaf color adapt respons chang environment factor also stress respons extern disturb studi evalu effect girdl color express rubrum leav studi phenotyp characterist physiolog biochem characterist transcriptom metabolom profil leav girdl non girdl branch rubrum	D031002	T002
36,280,827	head head comparison accuraci saliva nasal rapid antigen sar cov self test cross section studi diagnost accuraci unsupervis self test rapid antigen diagnost test ag rdts most unknown studi diagnost accuraci self perform sar cov saliva nasal ag rdt general popul	D000086402;D000086382	T005;T067;T047
36,280,826	use non government matern servic pregnanc outcom among undocu women cohort studi norway norway grant undocu women right antenat care give birth hospit includ general practition reimburs scheme respons limit access health care non government organ ngo run health clinic undocu migrant norway two largest citi facilit univers health coverag need investig pregnant undocu women use ngo clinic affect matern health therefor investig care receiv occurr pregnanc relat complic pregnanc outcom women receiv antenat care clinic	D047928;D011248	T046
36,280,825	role lipid metabol relat lncrna signatur risk stratif immun microenviron colon cancer energi metabol disord especi lipid metabol disord import biolog characterist colon cancer research sought examin associ lipid metabol relat long non code rnas lncrnas prognos among colon cancer patient	D062085;D003110	T123;T191;T114

36,280,968

associ chest xray cxr find outcom covid patient investig chest radiographi find suspect coronavirus diseas patient tertiari care set

D000086382

T047;T067

36,280,967

effect vibrat induc electr tooth brush amount canin retract cross section studi done univers lahor evalu effect local vibrat amount canin retract st premolar extract assess anchorag loss

D052280

T061

36,280,966

transloc acut precursor b cell lymphoblast leukaemia paediatr patient pakistani popul determin impact transloc paediatr patient diagnos precursor b cell acut lymphoblast leukaemia

D015452;D054198

T191

36,280,965

medic imag problem base learn impact student cross section studi investig medic student perform percept toward differ multimedia medic imag tool

D004504;D013337

T065;T097

36,280,964

big five inventori version two minut person measur tool urdu translat urdu valid big five inventori

D014177;D014175

T170;T057

36,280,963

urinari tract infect complic kidney stone correl guy stone score ascertain exist connect guy stone score infecti complic percutan nephrolitholapaxi

D007669;D014552;D009403

T061;T047

36,280,962

analys trend patient safeti non technic skill among postgradu traine modifi survey tool analys practic patient safeti non technic skill among postgradu traine establish util organis teach programm regard determin utilis differ teach mode

D061214;D002983

T058;T080

36,280,961

automat negat thought contribut factor adult convers disord see automat negat thought contribut convers disord adult

D004644;D003291

T041;T048

36,280,960

stutter relat psychosoci predictor impact stutter investig psychosoci factor impact person stutter problem

D013342

T184;T047;T048

36,280,959

relationship preoper smoke cessat anxieti postop anxieti pain prospect clinic trial univers hospit east turkey particip reveal relationship smoke cessat surgeri pre post oper anxieti pain among chronic smoker

D016540

T055

36,280,958

efficaci singl dose dermatolog tacrolimus ointment treatment vernal keratoconjunct assess safeti dermatolog tacrolimus ointment use topic efficaci treatment vernal keratoconvinctivti

D016559;D003233

T121;T047;T109

36,280,957

risk hypertens incid hospit cardiac arrest analys effect hypertens occurr hospit cardiac arrest find whether effect depend use anti hypertens drug

D058687;D016887;D004632;D006973

T061;T093;T058;T046;T047

36,280,946

technolog advanc stroke rehabilit earli coordin multidisciplinari rehabilit play major part motor recoveri stroke convent stroke rehabilit primarili includ physic therapi occup therapi speech therapi howev convent method mani stroke survivor still residu function disabl impair abil perform activ daili live could attribut insuffici therapi dose low engag motiv patient lack object feedback achiev signific improv function various technolog base stroke rehabilit intervent develop last decad shown promis result improv stroke patient function mobil independ use technolog promot repetit task specif train activ engag patient integr construct concurr feedback accur measur function improv review summar import technolog advanc stroke rehabilit includ exergam telerehabilit robot assist system virtual augment realiti wearabl sensor smartphon applic

D000071939;D020521

T061;T047

36,280,944

role diffus tensor imag brain tumour resect diffus tensor imag dti advanc imag techniqu help establish topograph anatom relationship tumour surround white matter tract intra oper use neuro navig help minim injuri function brain parenchyma decreas risk post oper neurolog deficit review assess efficaci dti brain tumour resect

D056324;D001932

T060;T191

36,280,943

strategi appetit suppress key player manag diabet obes peopl diabet obes advis curtail calori intak order improv glycaem control reduc weight howev mani patient complain inabl manag appetit therebi find difficult control calori intak dysregul appetit lead glycaem swing creat challeng metabol manag moreov short term non structur method suppress appetit often caus rebound excess food intak even overshoot baselin intak articl share non pharmacolog heurist hack help suppress optim appetit use day day clinic practic

D001066;D003920

T039;T040;T047

36,280,942

osteoporosi diabet dual pandem bone health import neglect aspect diabet care peopl type diabet known lower bone miner densiti bmd put greater risk osteoporosi fractur bmd type diabet often mislead multipl factor oper increas risk fall fractur articl provid overview osteoporosi diabet propos lemon mnemon understand multifacet aspect bone care

D003924;D050723;D010024;D058866

T047;T037

36,280,941

pruritus microvascular equival diabet pruriti common symptom mani system cutan local diseas diabet mellitus common syndrom multipl long term complic includ diabet pain neuropathi involv small fibr neuron diabet neuropathi recogn main pathophysiolog c fibr mediat sensat pain pruritus may belong differ neuron circuit evid cross talk therefor posit pruritus may symptom diabet neuropathi view equival microvascular diseas accompani clinic signific therapeut implic

D003929;D003920

T047

36,280,940

sexual behaviour chang seroneg limbic enceph due involv left amygdala limbic enceph le rare caus enceph general present neuropsychiatr manifest memori deficit seizur movement disord case year old femal patient le involv left amygdala present patient admit emerg depart complaint unconsci seizur paraneoplast limbic marker negat case diagnos seroneg le three four month diagnosi observ sexual prefer chang femal sex report publish far concern case le associ chang sexual behaviour patient treat intraven methylprednisolon ivp tripl antiepilept therapi treatment chang sexual behaviour return previous state

D020363

T047

36,280,939

function pituitari gonadotroph adenoma male patient case report pituitari gonadotroph adenoma common rare secret biolog activ lutein hormon lh follicl stimul hormon fsh case studi report high sex hormon testosteroneestrogen presenc high normal lh fsh report two case consent present visual disturb headach tertiari care hospit aga khan univers hospit karachi pakistan brain imag reveal pituitari macroadenoma workup consist pituitari gonadotroph adenoma high fsh case normal lhfsh case elev serum testosteron case transsphenoid resect perform tissu sampl histopatholog confirm pituitari adenoma postop improv hormon profil observ along resolut visual disturb headach thus function gonadotroph adenoma consid presenc elev testosteroneestrogen normal elev follicl stimul hormon fsh lutein hormon lh earli diagnosi lead better outcom

D010911;D052681;D000236

T191;T025

36,280,938

rare seen bilater posterior shoulder fractur disloc simultan bilater hemiarthroplasti posterior shoulder disloc rare condit bilater posterior shoulder fractur extrem rare disloc fractur bilater posterior shoulder observ often epilept seizur disloc posterior shoulder fractur rare clinician sometim experi difficulti diagnos time although diagnos treat earli base proper shoulder examin accur radiolog imageri treatment posterior shoulder disloc close reduct perform earli stage method osteosynthesi open reduct arthroplasti frequent use procedur delay stage studi shown first time literatur rare case disloc bilater posterior shoulder fractur epilept seizur year old patient good clinic function result follow simultan hemiarthroplasti treatment

D062785;D012784;D012783;D004827

T061;T047;T033;T037

36,280,937

post caesarean necrot soft tissu infect lead matern death case report necrot soft tissu infect lethal lead sepsi multi organ failur death describ case report us within hour caesarean section acut abdomin pain tachycardia tachypnoea local examin reveal larg area necrot subcutan tissu involv caesarean section scar immedi debrid carri repeat twice initi procedur could surviv

D018461;D063130;D018805

T047;T040;T046

36,280,936

covid associ anterior uveiti post covid acut anterior uveiti covid outbreak wuhan st decemb soon becam pandem ocular manifest post covid patient wide report anterior uveiti common form intraocular inflamm observ daili basi ophthalmologist diagnosi aau relat simpl identif etiolog difficult specif covid post covid aau report pakistan yet patient given case investig thorough possibl caus aau identifi patient manag uveiti

D000086382;D014606;D014605

T047;T067

36,280,935

extensor lag patient total knee arthroplasti without pre oper rehabilit regim short report total knee arthroplasti gain popular individu advanc stage knee osteoarthr among afford econom class aim studi assess effect preoper rehabilit manag post oper quadricep lag studi design non randomis clinic studi conduct januari march ghurki trust teach hospit lahor pakistan non probabl conveni sampl techniqu appli collect data patient tka data collect self design questionnair goniometr rang knee extens use main outcom independ sampl test appli assess differ group mean age patient year mean score extensor lag pre oper rehabilit regim without regim p valu valu studi show correl increas post oper extensor lag pre oper rehabilit regim

D019645;D020370

T061;T047

36,280,934

effect cervic stabilis exercis respiratori strength chronic neck pain patient forward head postur object studi determin effect cervic stabilis exercis respiratori strength chronic neck pain patient forward head postur studi conduct august februari jinnah hospit lahor patient fulfil elig criteria random assign two group experiment group control group baselin measur taken numer pain rate scale neck disabl index craniovertebr angl singl breath count spirometri measur retaken complet fourth week result signific p treatment group post intervent result reveal signific differ group p experiment group show improv four week cervic stabilis isometr exercis effect manag pain forward head postur neck disabl respiratori strength compar four week isometr exercis programm alon

D019547;D059350

T184;T047

36,280,933

paediatr penil percept score ppps hypospadia repaird present cross section studi sought evalu paediatr penil percept score ppps tool assess parent percept hypospadia repair children patient enrol studi median age year proxim hypospadia distal hypospadia hypospadia repair parentsguardian interview meatus glan skin general appear use standardis questionnair report penil appear penil percept overal median ppps score iqr signific differ penil percept score type hypospadia relationship person interview child mother father children age studi reveal penil percept score ppps valuabl tool use assess parent penil percept regard child penil appear note overal high satisfact hypospadia repair

D007021

T019

36,280,932

comparison effect haloperidol quetiapin acut manic episod studi conduct compar respons rate quetiapin haloperidol patient acut manic episod total patient acut episod mania baselin young mania rate scale ymrs includ random alloc either quetiapin group haloperidol group b patient assess baselin ymrs administ start follow visit six week comparison respons rate reduct ymrs statist signific two group vs p six week acut manic episod quetiapin haloperidol emerg equal effect pharmacolog strategi treatment bipolar mania quetiapin may use altern convent antipsychot haloperidol use replac quetiapin well low cost

D014150;D000087122

T033;T121;T039;T048

36,280,931

transposit basil vein vascular access haemodialysi experi tertiari care hospit basil vein transposit bvt prefer perman haemodialysi access due better patenc lower infect rate compar synthet graft outcom bvt case perform shifa intern hospit islamabad march june ambispect investig primari patenc fistula assess immedi surgeri hour day week month total patient includ studi male femal total patient underw one stage bvt underw two stage bvt one hundr thirti five procedur success surviv case fail mean basil vein diamet mm overal patient bleed fistula thrombos steal syndrom patient develop pseudo aneurysm conclud bvt feasibl techniqu good patenc rate especi patient multipl forearm avf surgeri

D001166

T061

36,280,930

fungal isol wound sampl submit cultur tertiari care hospit laboratori fungal wound infect increas worldwid aim retrospect studi conduct aga khan univers laboratori karachi pakistan determin frequenc fungal isol wound specimen data wound sampl receiv cultur countri septemb octob review sampl process bacteri cultur addit inocul sabouraud dextros medium demograph inform medic histori inform type wound collect total case includ cultur posit case yield fungi burn blast wound highest proport fungal isol ie candida speci common fungi n follow fusarium speci n studi report alarm rate fungal wound infect fungal necrotis wound infect high morbid mortal therefor import accur diagnos treat infect local set

D014946;D009181

T047;T046

36,280,929

develop banff classif identifi renal allograft reject narrat review nephrologist renal pathologist nephrologist transplant surgeon held meet banff canada develop classif scheme standardis intern classif renal allograft biopsi call banff classif follow first meet meet held usual everi two year revis classif light new evid techniqu latest print consensus meet pittsburgh unit state america sever articl publish last year creat ambigu nephrologist made thing challeng expert pathologist current perspect review plan make easi clear beginn practition banff classif evolv sinc incept

D016030

T061

36,280,928

long term prognosi culott versus differ crush strategi manag unprotect left main bifurc coronari lesion meta analysi assess long term clinic effect culott differ crush techniqu treatment unprotect left main bifurc coronari lesion determin best percutan coronari intervent strategi

D003324

T047

36,280,927

audit contrast extravas patient undergo contrast enhanc cts radiolog depart tertiari care hospit pakistan audit radiolog depart health facil focus contrast extravas manag pre post implement standard protocol

D005119;D011871

T046;T091;T037

36,280,926

effect util time non oper room anaesthesia servic aga khan univers hospit karachi prospect qualiti improv audit identifi servic qualiti gap review oper room anaesthesia servic tertiari care hospit

D058996;D000758

T061;T057

36,280,925

epidemiolog complic snakebit rural area badin thar sind pakistan identifi popul risk snakebit peak season site bite

D012909

T037

36,280,924

pain experienc patient epidur insert use gaug versus gaug epidur needl compar intens insert site pain epidur catheteris gaug needl gaug needl various time point number attempt taken locat epidur space use either needl

D004824;D000775

T061;T030

36,280,923

avail use autom extern defibril karachi pakistan cross section studi assess avail use autom extern defibril various public privat establish assess knowledg attitud practic relat use

D058687;D016887

T061;T046

36,280,922

correl serum malondialdehyd level preval cardiovascular diseas haemodialysi treat patient investig role serum malondialdehyd diagnost biomark free radic product cardiovascular diseas patient treat mainten haemodialysi

D059168;D002318

T201;T047

36,280,921

patient visit gastroenterolog clinic avoid give honest histori covid relat symptom pre clinic triag assess discrep term histori relat coronavirus diseas symptom given pre clinic triag doctor attend patient gastroenterolog clinic

D000086382;D005762

T047;T091;T067

36,280,920

fear covid stress univers student mediat role cyberchondria moder role creativ cope social support find moder role social support creativ cope mediat role cyberchondria relationship fear coronavirus diseas stress univers student

D000086382

T047;T067

36,280,919

associ matern nutrit status neonat anthropometri cross section studi identifi associ matern nutrit status neonat anthropometri

D009752;D014527

T033;T123;T114;T109

36,280,918

colostomi ileostomi care nurs educ effect synchron asynchron compar effect synchron asynchron train academ achiev e learn attitud nurs student train colostomi ileostomi care

D004506;D013338

T065;T097

36,280,917

preval vocal tract discomfort patient voic disord analys preval vocal tract discomfort patient voic disord

D014832

T033;T047

36,280,916

common caus hear impair among children less year age district bahawalpur punjab pakistan find common caus hear loss among young children compar caus along gender line

D010034;D034381;D010033

T033;T047

36,280,915

preval factor associ undernutrit among month children tehsil battagram pakistan find preval associ factor undernutrit semi rural set

D019282;D015362;D044342

T047

36,280,914

frequenc median nerv tight associ upper limb function among smartphon user public sector univers karachi determin median nerv tight smartphon user compar upper limb function without median nerv tight

D018737;D008475

T081;T023;T040

36,280,913

use system steroid pulmonari exacerb children adolesc cystic fibrosi determin role system steroid cystic fibrosi patient effect pulmonari exacerb children adolesc

D003550

T047

36,280,912

determin health promot behaviour self rate health life satisfact loneli among older person determin relationship health promot behaviour loneli life satisfact self rate health among elder

D008132;D006233

T033;T101

36,280,911

impact adipos paramet peak expiratori flow rate healthi young adult bahria univers medic dental colleg karachi cross section studi explor associ various adipos paramet young adult

D050154;D009765

T047;T032

36,280,910

correl prognosi cost effect comput tomographi hospit cardiac arrest patient return spontan circul emerg depart assess preval comput tomographi applic hospit cardiac arrest case emerg depart process contribut chang patient manag effect hospit discharg cost effect

D058687;D016887;D004632

T061;T058;T046;T093

36,280,909

translat valid stroke impact scale urdu pakistan translat valid urdu version stroke impact scale pakistani societi

D014177;D020521

T047;T170

36,280,908

outcom emerg vascular surgeri perform general surgeon experi univers hospit pakistan substitut vascular surgeon measur outcom emerg vascular surgeri perform general surgeon identifi prevent caus mortal

D014656;D066231

T061;T097

36,280,907

clinic spectrum sarcoidosi patient tertiari care hospit pakistan ten year follow studi identifi local pattern manifest organ involv lung diagnost tool treatment regimen relat patient sarcoidosi

D012507;D017563

T047

36,280,906

adapt preserv sturdi journey creat new normal phenomenolog insight factor affect medic resid journey consult practic explor factor promot hamper medic resid journey resid induct role adapt consult practic

D007396

T065;T097

36,280,905

effect light emit diod led cure mode depth cure doc bulkfil composit resin invitro studi evalu depth cure smart dentin replac bulkfil composit resin polymer constant puls ramp light emit diod cure mode

D003188;D011138

T122;T109

36,280,904

clinic outcom accord intent acut pesticid poison south korea retrospect observ studi investig intent pesticid intak could differ clinic outcom compar unintent poison whether acut alcohol consumpt correl intent poison

D010575;D011041

T131;T037

36,280,889

measur address stall develop health law educ chines univers health law educ import part global health educ benefici medic law school field help lawyer polici maker develop career equip tradit health profession doctor nurs basic knowledg health law howev unlik western univers health law educ china still infant stage lack systemat pedagog approach among institut higher educ china consid advanc field health law educ studi systemat review status health law educ institut higher learn china suggest way make pedagog approach consist systemat review reveal major law school medic school develop subject health law educ china lack consensus aim scope mode method health law educ first problem chines univers unabl agre classifi subject health law anoth set problem relat institut univers lack qualifi health law faculti also reli relat uninspir teach materi lead ineffect generic pedagog approach medic law school problem leav futur lawyer futur doctor nurs unclear choic health law studi graduat level ultim career develop therefor propos four preliminari solut continu develop new interdisciplinari subject health law educ chines univers clear classifi subject health law equip health law field profession textbook enact joint degre program medic school law school establish health law research center either law school medic school

D012577;D004500

T065;T073;T093

36,280,888

signific variat perform dna methyl predictor across data preprocess normal strategi dna methyl dnam base predictor hold great promis serv clinic tool health intervent diseas manag algorithm often high predict accuraci consist perform remain determin therefor conduct systemat evalu across differ dnam data preprocess normal strategi assess analyt strategi affect consist dnam base predictor

D019175

T044

36,280,884

hypox induc rest ventilatori circulatori respons multistep hypoxia relat declin peak aerob capac hypoxia sever factor shown contribut hypox induc declin aerob capac present studi investig effect rest hypox ventilatori cardiac respons hvr hcr hypox induc declin peak oxygen uptak formula see text peak

D010101;D000860

T201;T184;T033;T046

36,280,881

earli embryon lethal complex associ plp nubpl mutant mice variant mitochondri complex assembl factor nubpl associ rare caus complex defici mitochondri diseas patient affect complex defici harbor homozyg nubpl variant typic neurolog problem includ seizur intellectu disabl ataxia associ cerebellar hypoplasia thus far case report worldwid treatment avail rare diseas

D051844;D024101

T123;T116

36,280,878

pangenom wheat pathogen pyrenophora tritici repenti reveal novel transposon associ necrotroph effector toxa toxb fungal plant pathogen genom rearrang follow select pressur adapt trait facilit co evolutionari arm race host pathogen pyrenophora tritici repenti ptr emerg recent foliar pathogen wheat worldwid popul consist isol vari abil produc combin differ necrotroph effector effector play vital role diseas develop sequenc genom global collect isol ptr gain insight gene content genom rearrang

D009183;D001203

T131;T004;T109

36,280,877

epidemiolog dengu saarc territori systemat review meta analysi dengu one common arbovir infect public health problem south east asia aim systemat review meta analysi evalu preval distribut dengu saarc south asian associ region cooper countri

D003716;D003715;D013921

T005;T047

36,280,876

depress primari care role evid base guidelin cross section data primari care physician germani depress common mental health burden worldwid primari care physician pcps play key role care provis peopl depress first object present studi examin health care situat depress primari care focus cooper pcps mental health specialist second aim examin role german guidelin unipolar depress primari care provis

D058007

T097

36,280,874

clinic implic circul tumor dna predict outcom diffus larg b cell lymphoma patient receiv first line therapi circul tumor dna ctdna proven promis tumor specif biomark solid tumor clinic util risk stratif earli predict relaps diffus larg b cell lymphoma dlbcl well explor

D000074141;D016403

T191;T114

36,280,873

pro thrombot chang associ exposur ambient ultrafin particl patient chronic obstruct pulmonari diseas role lipid peroxid system inflamm exposur particul matter air pollut associ increas risk cardiovascular mortal patient chronic obstruct pulmonari diseas copd under mechan yet understood enhanc platelet pro thrombot activ copd patient may explain increas cardiovascular risk aim explor whether short term exposur ambient particul matter associ pro thrombot chang adult without copd investig under biolog mechan longitudin panel studi serum concentr thromboxan tx b measur reflect platelet pro thrombot activ lipoxygenas mediat lipid peroxid product hydroxyeicosatetraeno acid hete inflammatori biomark interleukin il monocyt chemoattract protein mcp tumour necrosi factor alpha tnf macrophag inflammatori protein mip measur potenti mediat determin particl associ pro thrombot chang

D000393;D000397;D029424

T131;T047;T069;T080

36,280,870

bifunct anti pd ltgf rii agent shr advanc solid tumor dose escal dose expans clinic expans phase trial dual inhibit pd pd l tgf pathway ration therapeut strategi malign shr new bifunct fusion protein compos monoclon antibodi pd l fuse extracellular domain tgf receptor ii first human trial aim assess shr pretreat advanc solid tumor find popul could benefit shr

D013274

T191

36,280,868

like pathogen pold variant associ mandibular hypoplasia deaf progeroid featur lipodystrophi syndrom chines patient mandibular hypoplasia deaf progeroid featur lipodystrophi syndrom mdpl omim rare autosom domin disord report case worldwid herein describ clinic featur under molecular etiolog mdpl syndrom year old chines patient

D003638;D008060

T033;T184;T047

36,280,866

narrat review centuri respiratori pandem spanish flu covid impact nanotechnolog covid diagnosi immun system boost rise high lethal sever acut respiratori syndrom sar corona virus covid remind us histori pandem happen last centuri spanish flu stay current centuri includ sever acut respiratori syndrom sar middl east respiratori syndrom mer corona virus covid review report newest find data origin pandem respiratori viral diseas reservoir transmiss mode analyz viral adapt need host switch determin pathogen causat factor pandem virus symptom clinic manifest conclud host factor associ pandem morbid mortal immun respons immunopatholog age effect pandem pregnanc addit focus burden covid non pharmaceut intervent quarantin mass gather facemask hygien medic intervent antivir therapi vaccin final investig nanotechnolog covid analysi immun system boost nanoparticl nps antimicrobi nps antivir immun cytokin review present insight use nanomateri treat covid improv bioavail abus drug diminish toxic improv perform

D000086382;D064149;D065207

T047;T005;T067

36,280,865

radiograph comput tomograph evalu supin sesamoid bone dog present studi evalu frequenc supin sesamoid bone ssb radiographi comput tomographi ct interobserv agreement evalu detect ssbs method correl exist ssbs elbow diseas ed assess purpos radiograph ct scan dog score observ

D012716

T023

36,280,863

relationship bodi mass index frailti caus mortal among middl age older adult parallel growth age obes popul preval metabol diseas rise bodi mass index bmi relat frailti mortal across frailti level controversi examin associ high bmi frailti mortal explor effect percent bodi fat associ

D000073496

T033;T184;T046

36,280,861

hospit initi pcsk inhibitor short term lipid control patient acut myocardi infarct proprotein convertas subtilisinkexin type pcsk inhibitor shown improv cardiovascular outcom ad convent statin therapi studi aim investig efficaci safeti hospit initi pcsk inhibitor among patient acut myocardi infarct ami base real world experi

D000924;D019161;D009203

T121;T047;T109

36,280,859

toe grip strength declin earlier hand grip strength knee extens strength communiti dwell older men cross section studi aim studi examin age relat chang toe grip strength differ hand grip strength knee extens strength use cross section data

D018737;D057187

T081;T056;T040

36,280,858

low abund popul distinguish microbiom perform plant cell wall deconstruct plant cell wall interwoven structur recalcitr degrad nativ adapt microbiom particular effect plant cell wall deconstruct although understand biolog cell wall deconstruct obtain isol cultiv microbiom break cell wall emerg new sourc biotechnolog relev microb enzym microbiom provid uniqu resourc identifi key interact function microbi group guid design special synthet microbi communiti

D064307

T001;T032;T028

36,280,857

sex specif exposur sex combin outcom two sampl mendelian random may mislead causal infer great interest read recent articl age menarch age natur menopaus risk rheumatoid arthriti mendelian random studi zhu et al great appreci work conduct author methodolog issu need reconsid first gender descript sampl age first birth studi wrong accord origin genom wide associ studi second studi exploit sex specif snps age menarch aam age natur menopaus anm sex combin effect snps rheumatoid arthriti ra possibl lead evid causat aam anm ra suggest author add possibl bias due issu limit problem mention recommend solut make articl perfect

D008572;D001172

T047;T040

36,280,856

cornin protect cerebr ischemiareperfus injuri prevent autophagi via pikaktmtor pathway ischemia stroke lead caus disabl consequ vascular occlus purpos studi investig effect cornin isol fruit verbena officinali l astrocyt autophagi induc cerebr ischemiareperfus cir injuri vitro vivo potenti mechan

D002545;D018696;D015427;D057889

T121;T109;T037;T047;T046;T169

36,280,855

postop weak anesthet associ rhabdomyolysi pediatr patient case report review literatur anesthesia associ rhabdomyolysi rare complic surgeri caus postop myalgia weak potenti renal failur manag prompt predispos condit may lead complic includ muscular dystrophi myopathi

D008305;D012206;D000777

T121;T039;T046;T037

36,280,854

deciph chloramphenicol biotransform mechan microbi interact via integr multi omic cultiv depend approach wide use broad spectrum antibiot chloramphenicol prone releas environ thus result disturb ecosystem stabil well emerg antibiot resist gene microb play vital role decomposit chloramphenicol environ biotransform process especi depend synergist interact metabolit exchang among microb herein comprehens chloramphenicol biotransform pathway key metabol enzym interspeci interact activ sludg enrich consortium elucid use integr multi omic cultiv base approach

D004785;D020578

T131;T007

36,280,853

crop manag shape divers activ dna rna virus rhizospher rhizospher hotspot microbi activ contribut ecosystem servic includ plant health biogeochem cycl activ microbi virus influenc plant microb interact rhizospher remain undetermin given impact virus ecolog evolut host communiti determin soil virus influenc microbiom dynam crucial build holist understand rhizospher function

D064307;D012328;D001435;D029688

T032;T168;T002;T005;T028;T001

36,280,852

clinic impact cardiac magnet reson patient suspect coronari arteri diseas associ chronic kidney diseas aquamarin ckd studi studi protocol random control trial although screen coronari arteri diseas cad use comput tomographi coronari angiographi patient stabl chest pain report benefici patient chronic kidney diseas ckd might limit benefit due complic contrast agent nephropathi decreas diagnost accuraci result coronari arteri calcif cardiac magnet reson cmr emerg novel imag modal detect coronari stenosi high risk coronari plaqu without contrast media affect coronari arteri calcif howev clinic use technolog robust evalu

D003324;D051436

T047

36,280,851

cost effect folic acid therapi primari prevent stroke patient hypertens hypertens patient without histori stroke myocardi infarct mi china stroke primari prevent trial csppt demonstr treatment enalapril folic acid reduc risk primari stroke compar enalapril alon whether folic acid therapi afford benefici treatment strategi primari prevent stroke hypertens patient chines healthcar sector perspect thorough explor

D006973;D020521

T047

36,280,850

effect mosquito rest site temperatur estim pathogen develop rate near natur habitat germani environment temperatur key driver transmiss risk mosquito born pathogen epidemiolog model usual relat temperatur data standard weather station data may captur relev scale mosquito experi environment temperatur mosquito assum spend lifetim rest site analys mosquito rest site pattern associ temperatur depend rest site type rest site height surround land use

D009033;D003465;D000852;D000330

T204

36,280,849

methotrex improv endotheli function earli rheumatoid arthriti patient month treatment endotheli dysfunct contribut increas cardiovascular cv diseas rheumatoid arthriti ra angiogen cell tang key regul vascular function via interact endotheli progenitor cell epc methotrex mtx associ reduc cv diseas risk effect endotheli homeostasi poor explor investig mtx effect endotheli homeostasi earli treatment nave ra patient

D018501;D001172

T121;T047

36,280,848

live liver donor underestim surgic outcom impact health relat qualiti life donat descript cross section studi south korea number live donor liver transplant live liver donor llds undergo surgeri postop recoveri process altruist purpos studi explor llds unmet expect surgic outcom examin impact donor health relat qualiti life hrqol

D019520;D016031

T061;T098

36,280,846

deleg patient relat task alli health assist time motion studi alli health assist aha support staff complet patient non patient relat task deleg alli health profession deleg patient relat task aha benefit patient alli health profession howev unclear whether aha workforc utilis optim provis patient care purpos studi determin proport time aha spend patient relat task work day differ across level aha experi clinic set profess deleg task

D000488;D032022;D016390

T077;T091;T097

36,280,845

immun relat histolog phenotyp pretreat tumour biopsi predict efficaci neoadjuv anti pd treatment squamous lung cancer although neoadjuv anti pd immunotherapi shown good efficaci non small cell lung cancer nsclc patient still lack effect predict marker aim develop pretreat histolog score system predict efficaci neoadjuv immunotherapi

D002289;D002294;D008175

T191

36,280,843

one plus one alway equal two structur differ nesfatin nesfatin nesfatin produc reaction n terminus human nucleobindin undergo proteolyt process date nucleobindin andor nesfatin shown act peptid hormon hand purpos nesfatin remain unknown sinc nucleobindin nesfatin thought impact control wide rang physiolog process includ energi homeostasi neurodegen process carcinogenesi ligandsinteract deserv special studi attent howev report molecular properti proteolyt product human nucleobindin literatur henc studi aim analyz effect zn ii ca ii human nesfatin structur herein report human nesfatin member intrins disord protein famili indic circular dichroism analyt ultracentrifug experi contrast found human nesfatin nesfatin structur globular intrins disord region zn ii treatment observ concentr depend structur compact intrins disord nesfatin propens oligomer well destabil nesfatin nesfatin furthermor dissoci constant zn ii bind nesfatin nesfatin nesfatin also report moreov structur distinct nesfatin seem interdepend link togeth indic observ molecular properti nesfatin turn simpl sum properti exhibit former peptid thus herein shed new light molecular behavior human nesfatin might help elucid complex function peptid video abstract

D064267;D036361

T125;T123;T116

36,280,842

metabolom profil prostat cancer specif surviv among finnish men abnorm metabol perturb metabol pathway play signific role develop progress prostat cancer howev comprehens metabolom analys human data lack need elucid interrelationship

D019207;D011471

T121;T191;T127;T109

36,280,841

loss npm express potenti immunohistochem marker malign periton mesothelioma singl center studi case malign periton mesothelioma mpm rare malign tumor high mortal rate extrem poor prognosi depth patholog analysi essenti assess tumor biolog behavior explor potenti therapeut target mpm nucleoplasmin npm molecular chaperon bind histon may play key role develop progress tumor studi aim analyz correl express level npm main clinicopatholog characterist prognosi mpm

D008175;D000086002;D056489;D010534;D010997;D019043

T123;T191;T116

36,280,840

sex specif chang triglycerid profil liver cirrhosi hepat c virus infect hepat c virus hcv infect associ serum lipid abnorm part normal follow direct act antivir daa therapi associ serum triglycerid tgs viral genotyp marker liver diseas sever evalu patient chronic hcv method studi includ serum patient chronic hcv tgs quantifi flow inject analysi fourier transform mass spectrometri laboratori valu noninvas score liver fibrosi assess determin nonparametr kruskalw test one way anova multipl linear regress student test use appropri p valu adjust multipl comparison

D019698;D006526

T047

36,280,839

efficaci metformin therapi patient cancer meta analysi randomis control trial investig whether metformin monotherapi adjunct therapi improv prognosi patient type cancer compar non metformin user age

D008687;D009369

T121;T191;T109

36,280,838

cchcr astrin interact promot centriol duplic recruit cep centrosom one import non membran organell regul microtubul organ progress cell mitosi coil coil alpha helic rod protein cchcr also known hcr gene consid psoriasi suscept gene protein suggest local p bodi centrosom mammalian cell howev exact cellular function hcr potenti regulatori role centrosom remain unexplor

D002502;D018797

T026;T123;T116

36,280,836

role continu medic educ program promot iranian nurs compet toward non communic diseas qualit content analysi studi continu medic educ essenti nurs provid qualiti patient care upgrad profession skill compet need continu medic educ cme becom appar face advanc medic scienc ever chang healthcar system nurs vital role improv health care therefor imper explor nurs experi cme cours extent program effect

D004502;D000073296

T065;T047

36,280,835

associ number remain teeth disabl free life expect impact oral self care older japanes adult prospect cohort studi tooth loss report associ shorter disabl free life expect dfle howev studi explor whether oral self care offset reduct dfle present studi aim assess associ oral self care dfle older individu tooth loss

D016388;D006233

T020;T101

36,280,834

non invas near infrar spectroscopi assess spinal neurovascular respons patient transvers myeliti case report transvers myeliti tm character acut develop motor sensori autonom dysfunct due horizont diffus inflamm one segment spinal cord absenc compress lesion well known inflamm process induc demyelin result neurolog dysfunct

D009188;D001342

T047

36,280,833

trend mortal alcohol opioid combin alcohol opioid poison sex educ attain race ethnic unit state ongo opioid epidem increas alcohol relat mortal key public health concern usa well document inequ degre group low high educ affect studi aim quantifi dispar time educ racial ethnic group sex specif mortal rate opioid alcohol combin alcohol opioid poison usa

D005006;D000701

T121;T098;T109;T131;T102

36,280,832

implement general practition general physician econsult servic econsult australia respons lengthi wait time specialist outpati appoint electron consult econsult servic develop global provid asynchron secur time communic general practition gp specialist studi aim track adopt queensland econsult servic two australian primari health network western queensland brisban south understand key barrier enabl adopt inform modif implement strategi method theori inform mix method evalu assess implement juli march adopt implement activ prospect record bespok track spreadsheet implement activ code expert recommend implement chang eric strategi semi structur interview gps stakehold inform consolid framework implement research cfir conduct understand determin implement result practic invit take part econsult servic enrol gps consent sent least one request advic rfa econsult total rfa sent implement predomin guid eight strategi qualit interview conduct gps stakehold ruralremot region femal two sole practition interviewe felt econsult servic support outpati appoint avoid provid effici time access specialist support gps patient barrier identifi use econsult relat digit infrastructur compet prioriti keep servic front mind key enabl identifi relat advantag econsult option patient benefit covd facilit use digit technolog

D058005;D012017

T058;T170;T097

36,280,830

pattern treatment outcom rectal cancer concurr locoregion recurr distant metastas total mesorect excis studi pattern treatment outcom rectal cancer rc concurr locoregion recurr lr distant metastasi dm total mesorect excis tme identifi patient diseas treatment relat factor associ differ prognosi concurr lr dm

D009364;D012004

T191

36,280,829

rbck endogen inhibitor tripl negat breast cancer via hippoyap axi tripl negat breast cancer tnbc one lethal breast cancer subtyp due lack effect therapeut target chemotherapi still main medic treatment tnbc patient thus import necessari find new therapeut target tnbc recent genom studi implic hippo yap signal activ tnbc manifest play key role tnbc carcinogenesi cancer progress rbck first identifi import compon linear ubiquitin assembl complex lubac facilit nfkb signal immun respons studi show rbck also facilit lumin type breast cancer growth endocrin resist via tran activ estrogen receptor alpha

D064726

T191

36,280,828

transcriptom metabolom analys reveal girdl promot leaf color express acer rubrum l acer rubrum l red mapl popular tree attract color leav strong physiolog adapt high ornament valu chang leaf color adapt respons chang environment factor also stress respons extern disturb studi evalu effect girdl color express rubrum leav studi phenotyp characterist physiolog biochem characterist transcriptom metabolom profil leav girdl non girdl branch rubrum

D031002

T002

36,280,827

head head comparison accuraci saliva nasal rapid antigen sar cov self test cross section studi diagnost accuraci unsupervis self test rapid antigen diagnost test ag rdts most unknown studi diagnost accuraci self perform sar cov saliva nasal ag rdt general popul

D000086402;D000086382

T005;T067;T047

36,280,826

use non government matern servic pregnanc outcom among undocu women cohort studi norway norway grant undocu women right antenat care give birth hospit includ general practition reimburs scheme respons limit access health care non government organ ngo run health clinic undocu migrant norway two largest citi facilit univers health coverag need investig pregnant undocu women use ngo clinic affect matern health therefor investig care receiv occurr pregnanc relat complic pregnanc outcom women receiv antenat care clinic

D047928;D011248

T046

36,280,825

role lipid metabol relat lncrna signatur risk stratif immun microenviron colon cancer energi metabol disord especi lipid metabol disord import biolog characterist colon cancer research sought examin associ lipid metabol relat long non code rnas lncrnas prognos among colon cancer patient

D062085;D003110

T123;T191;T114