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biomedical-topic-categorization-validation

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36,267,999
ad valu contrast enhanc ct radiom differenti tuberculosi non tubercul infecti lesion present solid pulmonari nodul mass compar valu contrast enhanc ct cect non contrast enhanc ct ncect radiom model differenti tuberculosi tb non tubercul infecti lesion ntil present solid pulmonari nodul mass develop combin radiom model rm
D014057;D014376
T060;T047
36,267,998
exposur n n diethyl toluamid cardiovascular diseas adult although grow evid suggest n n diethyl toluamid deet advers effect public health relationship deet cardiovascular diseas cvd still larg unknown purpos studi therefor evalu associ deet exposur total specif cvd among us adult cross section studi total particip select nation health nutrit examin survey nhane cvd defin combin congest heart failur chf coronari heart diseas chd angina heart attack stroke logist regress model use evalu associ deet metabolit risk total specif cvd compar lowest quartil diethylcarbamoyl benzoic acid dcba highest quartil associ increas risk cvd odd ratio ci p trend chd ci p trend adjust potenti covari nevertheless exposur dcba signific associ heart attack chf angina stroke studi requir confirm find identifi under mechan
D002318;D009203;D020521
T047
36,267,997
associ close interperson contact vaccin hesit find popul base survey canada vaccin hesit threaten effort bring coronavirus diseas covid pandem end given social interperson contact import driver covid transmiss understand relationship contact rate vaccin hesit may help identifi appropri target strateg intervent purpos studi assess associ interperson contact covid vaccin hesit among sampl unvaccin adult canadian provinc british columbia bc
D000086382;D014612
T129;T121;T116;T067;T047
36,267,996
preval correl suspect dementia older adult receiv primari healthcar wuhan china multicent cross section survey integr manag dementia primari healthcar cost effect way reduc burden dementia clinic epidemiolog dementia primari healthcar set remain unclear studi investig preval correl suspect dementia chines older adult receiv primari healthcar
D002561;D003704
T047;T048
36,267,995
glycem control influenc factor type diabet patient anhui china investig status glycem control analyz influenc factor patient type diabet td anhui china
D003924
T047
36,267,994
anxieti symptom older chines adult primari care set preval correl integr mental health servic primari care potenti cost effect way decreas treatment gap anxieti older adult data epidemiolog anxieti symptom older chines adult primari care set limit studi investig preval correl anxieti symptom chines older primari care patient
D010300;D013276;D006973
T047
36,267,993
trend myopia develop among primari junior school student post covid epidem period investig trend myopia among primari junior school student post covid epidem period
D000086382;D009216
T047;T067
36,267,992
cumul exposur elev blood pressur better predict cardiovascular diseas risk rural chines adult tradit risk estim cardiovascular diseas cvd base current blood pressur bp howev whether cumul exposur elev bp among rural individu addit prognost valu unclear aim valid associ cumul bp cvd occurr assess prognost valu cumul bp cvd risk predict
D002318;D006973
T047
36,267,991
medic use cost nativ father children transnat marriag famili taiwan first studi examin health care util term medic use cost nativ father children transnat famili
D008393;D003695
T080;T055;T093;T062;T033;T079;T054;T081;T058;T072
36,267,990
applic valu joint stop bang questionnair epworth sleepi scale screen obstruct sleep apnea paper evalu applic valu stop bang questionnair combin epworth sleepi scale ess screen obstruct sleep apnea osa popul
D000077260;D020181
T047;T048
36,267,989
evalu risk hypertens resid primari care shanghai china machin learn algorithm prevent hypertens primari care requir effect suitabl hypertens risk assess model aim studi develop compar perform three machin learn algorithm predict risk hypertens resid primari care shanghai china
D000069550;D006973
T047;T066
36,267,988
factor structur measur invari chines version covid phobia scale depress symptom sampl covid closur exploratori structur equat model approach covid phobia scale instrument measur phobia coronavirus stabl four factor structur good reliabl valid countri region order expand relat research studi aim test reliabl valid covid phobia scale chines adolesc depress symptom cp sc translat chines method forward back translat test chines adolesc depress symptom confirmatori factor analysi cfa exploratori structur equat model esem use test compar four factor model cp sc test measur invari cp sc across gender time final reliabl measur mcdonald omega coeffici consist previous studi cp sc show stabl four factor structur result show esem better cfa reason addit result multi group esem show cp sc met strict invari male femal partial longitudin strict invari mcdonald omega coeffici cp sc total scale subscal reach expect accept level short reliabl valid index cp sc reach accept level measur invari differ gender differ time point establish cross factor phenomenon individu item abnorm revis test still need
D000086382;D010698
T047;T067;T048
36,267,873
interperson psychotherapi versus sertralin women posttraumat stress disord follow recent sexual assault random clinic trial background sexual assault often trigger posttraumat stress disord ptsd potenti chronic sever mental disord guidelin recommend select serotonin reuptak inhibitor ssris trauma focus psychotherapi treatment option interperson psychotherapi ipt adapt ptsd ipt ptsd focus interperson consequ trauma rather confront trauma studi found ipt ptsd efficaci reduc ptsd symptom limit attrit efficaci trial compar ipt ptsd ssri hypothes ipt would reduc ptsd anxieti depress symptom sertralin among women ptsd follow recent sexual assault object compar efficaci ipt ptsd ssri sertralin week random clinic trial women ptsd follow recent sexual assault method seventi four women ptsd suffer sexual assault last six month random assign week ipt ptsd n sertralin n instrument assess ptsd anxieti depress symptom random clinic trial conduct paulo brazil use clinician administ ptsd scale cap primari outcom measur result treatment signific reduc ptsd anxieti depress symptom without group outcom differ cap mean decreas sd sd sertralin sd sd ipt ptsd attrit high arm p conclus trial show within group improv without differ ipt ptsd sertralin treatment ptsd find suggest non exposur base psychotherapi may benefit patient ptsd although direct compar treatment exposur therapi brazilian clinic trial registri rbr zz
D013313;D000079062;D007171;D012742
T061;T037;T048
36,267,846
studi medic rule tradit chines medicin treat constip data mine network pharmacolog explor rule tcm medic treatment constip network pharmacolog
D008516;D004365
T060;T123;T121;T091
36,267,845
predict model residu neural network patholog confirm lymph node metastasi ovarian cancer want develop model predict lymph node status base positron emiss comput tomographi pet imag untreat ovarian cancer patient use featur map form wavelet transform paramet obtain imag segment build model model expect help clinician provid addit inform first visit patient
D016571;D010051
T170;T191
36,267,844
improv epidemiolog model underprivileg peopl contemporari pandem work introduc improv form basic seird model base python simul troublesom peopl oblivi contemporari pandem due divers social impedi especi econom underprivileg extant epidemiolog model unorthodox issu yet consid poverti illiteraci careless toward health issu signific influenc data model focus overcom issu ad two branch instanc uncov apathet peopl signific influenc practic purpos data simul use python base algorithm train desir system base set real time data propos model provid predict data certain level accuraci compar discuss statist error analysi correl regress analysi introduc valid propos epidemiolog model show numer evid investig compris figur tabular mode real time predict data final discuss conclud remark base find
D058873;D000090005
T170;T067
36,267,843
long noncod rna dscam facilit prolifer migrat hemangioma endotheli cell target mir ptpd axi diagnos kind vascular neoplasm infanc hemangioma ha occur main due aberr prolifer endotheli cell exist evid manifest close relationship long noncod rnas lncrnas pathogenesi ha although lncrna dscam antisens rna dscam reveal implic progress human diseas under mechan dscam exert ha format unclear
D062085;D035683;D006391
T123;T191;T114
36,267,842
proteom analysi decellular extracellular matrix achiev compet biomateri osteogenesi decellular ecm use biolog scaffold tissu repair due tissu specif biochem mechan composit poor simul materi use patch powder could process via enzymat digest acid condit use pepsin howev part bioactiv lost digest process due protein denatur stepwis digest develop prepar compet biomateri osteogenesi three differ ecm sourc addit three differ proteas compar evalu effect digest protocol specif cellular process gag peptid quantif show stepwis method yield higher concentr bioactiv residu circular dichroism analysi also show stepwis approach preserv secondari structur better protein profil digest ecm analyz found high divers tissu specif digest ecm pericardium produc peptid origin differ protein follow protein ecm tendon protein ecm bone addit digest product pericardium ecm yield increas prolifer differenti bone marrow mesenchym stem cell matur osteoblast
D010012;D001672
T122;T042
36,267,841
compar pharmaco histokinet therapeut dose estradiol valer bromocriptin common quail current studi aim examin overal effect steroid tissu organ pharmacotherapeut pharmaco histokinet sever steroid includ bromocriptin mesyl estradiol valer common quail coturnix coturnix total bird use pharmaco histokinet research carri two separ trial one fall season spring season experi last five ten fifteen twenti day studi group use bird base experi control group stretch five ten fifteen twenti day season therapeut dosag administ sum two group repres two separ steroid trial group steroid administ bird therapeut dose three drop administ twice daili clinic symptom includ despond sluggish variat weight temperatur almost treat bird display howev trial conduct fall sizabl degre bodi enlarg one treat bird notic winter test show mortal rate four bird die twenti day group one bird die treat estradiol valer three bird die treat bromocriptin mesyl male femal bird show sign lost bodi weight treat bird kidney stomach heart liver exhibit edema comparison almost bird show enter indic steroid main affect intestin appar differ histolog analysi heart skelet muscl treat bird control group kidney liver intestin show major histopatholog chang treat bird
D003370;D001971
T121;T012;T109
36,267,840
applic sandwich teach method base network platform rehabilit nurs teach postepidem era rehabilit nurs teach one key point nurs teach qualiti rehabilit nurs teach direct affect comprehens abil clinic intern therefor teacher must deepen reform clinic nurs teach improv teach system explor effect clinic nurs teach method paper introduc applic network teach mode base sandwich rehabilit nurs teach provid guidanc help clinic nurs teach mode sandwich teach activ third year student nurs depart take master theoret knowledg chang critic think abil chang learn initi indic paper analyz sandwich teach mode discuss cultiv nurs student abil experiment result show intervent statist signific differ learn initi student experiment group p intervent signific differ learn initi control group p
D019145;D013338
T091;T097
36,267,839
manag strategi alzheim patient medic care integr model base big data evalu context era big data manag alzheim patient arous widespread concern societi elder peopl dementia societi accommod special group arous heat discuss societi goal medic nurs integr model realiz integr model medic care nurs rehabilit old care better satisfi need provid medic servic rehabilit care health manag medic need elder help elder maintain healthi state elder care need better met elder care servic burden famili societi reduc advanc medic care integr model new solut provid manag senil dementia patient therefor medic care integr model paper manag alzheim patient base big data algorithm base associ rule compar manag alzheim patient tradit model drew follow conclus compar manag satisfact alzheim patient tradit model famili member patient total satisfact nurs manag medic care integr model great improv compar manag alzheim patient tradit model incid advers event manag alzheim patient medic care integr model great reduc reduc medic care integr model anxieti depress score elder patient dementia decreas rapid medic care integr model live abil senil dementia patient great improv use medic care integr model manag senil dementia patient great improv sleep qualiti mental qualiti qualiti life senil dementia patient
D000544
T047;T048
36,267,838
cytotox hybrid nobl metal polym composit aim present research assess cytotox gold silver nanoparticl synthes dextran graft polyacrylamid paa polym nanocarri use basi prepar multicompon nanocomposit reveal high efficaci antitumor therapi evalu influenc polym system viabil metabol activ fibroblast eryptosi elucid mechan proeryptot effect done current research nanocomposit investig studi reduc surviv fibroblast even highest use concentr find suggest hybrid agd paa composit activ eryptosi via ros ca mediat pathway low concentr contrast studi materi thus cytotox agd paa composit erythrocyt pronounc compar paa hybrid aupolym composit eryptosi sensit tool assess biocompat nanomateri compar fibroblast viabil assay
D053768;D053761
T073
36,267,837
impact neutrophil lymphocyt ratio febril seizur systemat review meta analysi meta analysi conduct determin relationship neutrophil lymphocyt ratio nlr febril seizur fs studi regist prospero id crd web scienc embas pubm scopus proquest central search final studi includ standard mean differ smd report confid interv ci nlr level compar febril control group fs patient nlr level signific higher smd ci p furthermor conduct comparison nlr level febril control simpl complex fs case separ found nlr level children either simpl complex fs higher compar febril control smd ci p smd ci p respect also comparison nlr level simpl fs group complex fs patient nlr level signific higher smd ci p studi indic nlr could recommend inexpens diagnost biomark fs addit use distinguish simpl fs complex fs
D009504;D003294
T047;T025
36,267,836
comparison proxim phytonutri composit cashew nut appl differ geograph area burkina faso cashew plant allogam plant produc two type fruit nut cashew appl present studi conduct perform comparison proxim phytonutri composit cashew anacardium occidental l nut appl differ geograph area burkina faso purpos sampl appl kernel collect three main cashew cultiv area nutrit potenti cashew nut appl produc evalu enhanc food process protein carbohydr lipid dietari fiber ascorb acid tannin anthocyanin chlorophyl lycopen caroten content assess result reveal high content lipid g gdw protein g gdw starch g g dw almond appl hand rich lipid ascorb acid mg g solubl sugar mg g pigment lycopen anthocyanin caroten chlorophyl summari almond may suitabl sourc lipid relat product appl use natur antioxid produc juic data import clue cashew product process result obtain provid scientif basi food econom valor cashew fruit
D031021
T168;T002
36,267,835
novel target studi cure cardiovascular diseas regard proprotein convers subtilisinkexin type studi aim screen potenti ideal lead compound natur drug librari zinc databas potenti inhibit effect proprotein convers subtilisinkexin type pcsk contribut enrich practic basi pcsk inhibitor screen
D000071449;D002318
T047;T126;T116
36,267,817
pcbp reduc oxid stress induc apoptosi glioma cgasst pathway mettl mediat modif preval primari malign tumor cns glioma dismal prognosi theori oxid stress one import theori studi occurr develop mechan studi impact pcbp glioma suffer possibl mechan examin
D005910;D008780;D018384;D016601
T123;T116;T049;T191;T126
36,267,816
overexpress mir aggrav sepsi induc myocardi hypertrophi bind rcan mediat activ sepsi remain complic incomplet understood syndrom myocardi dysfunct one main complic contribut poor clinic outcom accumul evid reveal critic involv deregul express specif microrna mirna cardiac patholog caus sepsi intrigu mir correl cardiomyocyt apoptosi wherea effect myocardi hypertrophi remain illustr thus current studi set explor impact under mechan mir myocardi hypertrophi induc sepsi express pattern mir detect myocardi tissu septic mice induc cecal ligat perfor clp found mir high express myocardi tissu clp induc septic mice cardiomyocyt hypertrophi besid mir inhibit could reliev cardiomyocyt hypertrophi reduc inflamm septic mice mechanist studi found mir could target rcan regul calcineurin activ via ca signal pathway collect find illumin mir enhanc myocardi hypertrophi caus sepsi target rcan regul ca signal pathway work highlight downregul mir novel target manag sepsi induc myocardi hypertrophi
D019703;D006332;D035683;D018805;D047908
T123;T116;T033;T126;T114;T047;T046
36,267,815
nuclear morpholog alter erythrocyt antioxid enzym genet dispar induc brackish water mrigal carp cirrhinus mrigala salin aquat ecosystem abrupt climat chang anthropogen activ caus advers impact agricultur landsoil well aquacultur industri experiment studi design evalu differ biomark oxid stress antioxid enzym genotox potenti divers salin brackish water freshwat fish total fresh water mrigal carp cirrhinus mrigala random segreg maintain four group glass aquarium similar laboratori condit various salin level part per thousand determin patholog influenc brackish water fish group expos various salin level brackish water period day fish group serv control group experiment fish rear differ group display various physic behavior ailment result reveal signific augment quantiti differ oxid stress indic includ reactiv oxygen speci ros thiobarbitur acid reactiv substanc tbar differ viscer tissu kidney liver gill expos fish differ antioxid enzym reduc glutathion gsh peroxidas pod superoxid dismutas sod catalas cat along total protein remark reduc kidney gill liver tissu result show signific increas valu differ nuclear abnorm erythrocyt micronucleus erythrocyt condens nucleus erythrocyt lobe nucleus morpholog chang pear shape erythrocyt spindl shape erythrocyt spherocyt red blood cell experiment fish result genotox effect exhibit signific increas dna damag isol cell liver kidney gill expos fish find experiment research suggest brackish water caus advers toxicolog impact differ viscer tissu fresh water fish higher salin level disrupt disord physiolog biochem marker
D002347;D014874
T131;T013
36,267,814
automat detect segment ovarian cancer use multitask model pelvic ct imag ovarian cancer one common malign tumour femal reproduct organ world pelvic ct scan common examin method use screen ovarian cancer show advantag safeti effici provid high resolut imag recent deep learn applic medic imag attract attent research field tumour diagnost howev due limit number relev dataset reliabl deep learn model remain challeng problem detect ovarian tumour ct imag work first collect ct imag ovarian cancer patient affili hospit qingdao univers new end end network base yolov propos name yolo ocv ovarian cancer improv previous work yolo oc first includ balanc mosaic data enhanc decoupl detect head base detect model multitask model propos simultan complet detect segment task
D000077321;D010051
T191;T066
36,267,813
role ampk myocardi ischemia reperfus injuri induc cell death presenc absenc diabet recent studi indic cell death hallmark cardiac patholog myocardi infarct diabet amp activ protein kinas ampk signal pathway consid putat salvag phenomenon play decis role almost cellular metabol surviv function therefor entail precis regul activ ampk regul various program cell death depend stimuli context includ autophagi apoptosi necroptosi ferroptosi substanti evid suggest ampk regul cardiac tissu anim human type diabet metabol syndrom compar non diabet control stimul ampk physiolog pharmacolog amelior diabet associ cardiovascular complic myocardi ischemia reperfus injuri furthermor ampk excit therapeut target develop novel drug candid treat cell death diabet associ myocardi ischemia reperfus injuri therefor review summar ampk regul autophag apoptot necroptot ferroptosi pathway context myocardi ischemia reperfus injuri presenc absenc diabet
D015428;D003924
T047;T046
36,267,812
associ serum homocystein cardiovascular caus mortal adult diabet prospect cohort studi homocystein hci implic oxid stress diabet biolog howev clinic evid link hci level diabet limit controversi studi aim investig associ serum hci caus cardiovascular mortal diabet patient
D003924;D002318;D009369
T047;T191
36,267,811
activ ptenpkakt signal pathway mirna p load nanoparticl regul oxid stress attenu cardiomyocyt regul myocardi injuri common cardiovascular diseas acut myocardi infarct serious affect health life patient mirna play import role acut myocardi infarct base mirna obtain previous sequenc studi investig whether mirna mir p load nanoparticl nps affect phenotyp acut myocardi infarct ami rat nano mir p decreas myocardi infarct area improv myocardi tissu structur increas degre fibrosi nano mir p decreas apoptosi express cleav caspas indic role protect repair myocardium verifi action mechan mirna potenti target gene mir p pten identifi starbas confirm use doubl luciferas assay follow cotransfect nano mir p pten area tissu structur damag myocardi infarct fibrosi substanti elev express cleav caspas apoptosi rate nano mir p pten cotransfect group also signific increas bioinformat analysi reveal mirna may regul oxid stress injuri target pten taken togeth mir p could protect repair myocardi tissu target pten
D035683;D009203;D053758
T123;T047;T073;T114
36,267,810
integr bioinformat analysi reveal mitochondri dysfunct relat gene under intervertebr disc degener mitochondri dysfunct play import role intervertebr disc degener idd aim explor pathway key gene caus mitochondri dysfunct idd reveal pathogenesi idd base bioinformat analys
D055959;D007403;D035683
T123;T190;T023;T114;T047
36,267,809
circmtnd particip renal mitochondri injuri fibrosi spong mir lupus nephriti recent studi focus nuclear encod circular rnas circrna kidney diseas littl known mitochondri circrna differenti express circrna analyz rna deep sequenc lupus nephriti ln biopsi normal human kidney ln renal biopsi downregul circrna circmtnd encod mitochondri genom quantit circmtnd qpcr local fluoresc situ hybrid fish mitochondri abnorm identifi electron microscopi express mitochondri gene decreas express profibrot gene increas qpcr immunostain rna bind site mir circmtnd predict mir express increas fish qpcr hk cell mitochondri fraction role circmtnd spong mir assess coloc mitochondria fish rna immunoprecipit rna pulldown coupl luciferas report assay circmtnd knockdown upregul mir decreas mitochondri function gene express increas profibrot gene express overexpress circmtnd revers effect htgf stimul hk cell similar effect observ hk cell overexpress knockdown mir conclud circmtnd allevi renal mitochondri injuri kidney fibrosi spong mir ln
D007674;D008181;D035683;D000079962
T123;T047;T114
36,267,808
nicandra physalod extract exert antiag effect multipl model extend lifespan caenorhabd elegan via daf hsf develop safe effect therapeut intervent import issu delay age reduc risk age relat diseas chines herbal medicin treatment age complex diseas desir due multipl compon target screen effect lifespan chines herbal medicin extract nicandra physalod extract hl found exhibit lifespan extens activ caenorhabd elegan c elegan experi hl improv healthspan enhanc stress resist delay progress neurodegen diseas c elegan addit amelior senesc human lung fibroblast mrc cell revers liver function damag reduc senesc marker level doxorubicin dox induc age mice addit longev effect hl c elegan depend daf hsf signal pathway demonstr result mutant lifespan gene level gfp level assay summari discov hl antiag effect c elegan mrc cell dox induc age mice deserv explor futur studi antiag agent
D029742;D004365
T123;T121;T116
36,267,693
outcom covid kidney transplant recipi sar cov variant era role anti sar cov monoclon antibodi kidney transplant recipi ktr increas risk covid associ complic aim describ evolv epidemiolog outcom pcr document sar cov infect ktr follow institut march may primari endpoint hospit covid relat symptom death within day diagnosi overal case includ develop primari outcom signific decreas incid primari outcom observ p r studi period anti spike monoclon antibodi mab administ earli treatment within day onset symptom patient casirivimabimdevimab sotrovimab among patient receiv least one vaccin dose infect patient consid adequ vaccin multivari analysi reveal charlson comorbid index p ci associ primari outcom earli administr mab p ci associ better outcom infect period omicron variant predomin adequ vaccin
D000086382;D016030
T061;T047;T067
36,267,666
comparison efficaci safeti temporari spinal cord stimul versus puls radiofrequ postherpet neuralgia prospect random control trial object studi compar safeti effect temporari spinal cord stimul scs versus puls radiofrequ prf treat postherpet neuralgia phn
D051474;D062187;D061208
T061;T047
36,267,665
multidisciplinari nonpharmacolog manag pain temporomandibular disord tmds temporomandibular joint dysfunct tmd singl diagnosi term cover group condit involv pain dysfunct masticatori muscl within temporomandibular joint tmj associ structur set diseas entiti compris various ailment clinic symptom one distress symptom tmd patient pain pain subject alway unpleas vas visual analogu scale use research aim studi assess influenc physic stimuli name extrem low frequenc magnet field elf mf led light experi pain caus increas tension masticatori muscl adult peopl examin enrol studi meet elig criteria studi group divid subgroup subgroup receiv physic therapi treatment use differ physic stimulus effect four therapeut modal compar term vas score pain attenu observ subgroup studi confirm analges effect select physic therapi method author focus analysi result obtain subgroup compar effect individu modal pain intens accord vas score treatment pain relief observ studi subgroup treatment use elf mf elf mf combin led light cours tmd bring signific improv subject pain experi express vas pain score use select physic stimuli benefici effect pain symptom mandibular movement import implic patient daili life work incorpor therapeut method help enhanc patient satisfact comfort manual tmj therapi lengthi dental procedur
D013705
T047
36,267,573
irisin crossroad inter organ communic challeng implic physiolog function organ intercommun occur secret molecul exercis improv physiolog function organ tissu believ secret myokin muscl target remot organ howev under mechan exercis regul inter organ communic remain incomplet understood yet recent identifi myokin irisin primarili found muscl adipos subsequ extend bone heart liver brain provid new molecular evid inter organ communic secret regul exercis mediat intercommun exercis organ best understand regulatori mechan review discuss recent evid involv potenti molecular pathway inter organ communic interact signal irisin regul impact exercis organ function also discuss
D005353;D018482
T123;T023;T116;T024
36,267,572
key hepat signatur human mous nonalcohol steatohepat transcriptom proteom data meta analysi despit global preval nonalcohol fatti liver diseas nafld pathophysiolog remain unclear studi establish high confid nonalcohol steatohepat nash gene signatur evalu patholog mechan under nash systemat meta analysi transcriptom proteom dataset obtain nash patient mous model
D065626
T047
36,267,571
current insight appli mri grave ophthalmopathi grave ophthalmopathi go autoimmun diseas relat grave diseas gd therapeut strategi go patient base precis assess activ sever diseas howev current assess system requir develop accommod updat treatment protocol import adjunct examin magnet reson imag mri help physician evalu go accur continu updat mri technolog deepen understand go assess diseas mri gone stage qualit precis quantif make possibl clinician monitor microstructur chang behind eyebal better integr clinic manifest patholog review use orbit structur classif combin patholog chang mri featur also review mri techniqu appli go clinic practic diseas classif region interest select
D049970;D006111
T047
36,267,570
endogen glp level play import role determin efficaci dpp iv inhibitor prediabet type diabet contrast western popul glucagon like peptid glp level preserv east asian popul type diabet td explain dipeptidyl peptidas iv dpp iv inhibitor effect east asian assess whether differ endogen glp level result differ treatment respons dpp iv inhibitor prediabet td
D054873;D003924;D011236;D007333
T121;T047;T046
36,267,569
function pharmacolog role dopamin receptor polymorph variant function pharmacolog signific dopamin receptor r remain least well understood dopamin receptor subtyp even enigmat role preval human drd gene polymorph region encod third intracellular loop receptor common polymorph encod r repeat prolin rich sequenc amino acid r r drd polymorph associ individu differ link impuls control relat neuropsychiatr disord consist associ establish gene encod r attent deficit hyperact disord adhd substanc use disord function r polymorph variant reveal address role receptor heteromer relat avid norepinephrin r review evid convey signific differenti role r r dopaminerg noradrenerg modul frontal cortico striatal pyramid neuron implic moder construct impuls person trait differenti role depend abil confer differ properti adrenerg receptor r r heterom dopamin receptor r r heterom preferenti local perisomat region frontal cortic pyramid neuron striatal termin respect also review evid support r therapeut target adhd impuls control disord well restless leg syndrom
D050638;D004298
T123;T121;T116;T109;T192
36,267,568
fatti acid metabol relat gene bronchoalveolar lavag fluid unveil prognost immun infiltr idiopath pulmonari fibrosi idiopath pulmonari fibrosi ipf chronic progress condit unfavor prognosi recent studi demonstr ipf patient exhibit characterist alter fatti acid metabol lung suggest associ ipf pathogenesi therefor studi explor whether gene signatur associ fatti acid metabol could use reliabl biolog marker predict surviv ipf patient
D054990
T047
36,267,567
regulatori network interplay hepatokin stellakin myokin adipokin nonalcohol fatti liver diseas nonalcohol steatohepat fatti liver diseas spectrum liver patholog rang simpl hepat steatosi non alcohol fatti liver diseas nafld non alcohol steatohepat nash culmin develop cirrhosi hepatocellular carcinoma hcc pathogenesi nafld complex divers lack effect treatment measur review address hepatokin identifi pathogenesi nafld nash includ signal fxrrxr pparrxr adipogenesi hepat stellat cell activationliv fibrosi ampknf b type diabet also highlight interact hepatokin cytokin peptid secret muscl myokin adipos tissu adipokin hepat stellat cell stellakin respons certain nutrit physic activ cytokin exert autocrin paracrin endocrin effect pathogenesi nafld nash character signal pathway crosstalk amongst muscl adipos tissu hepat stellat cell liver cell enhanc understand interorgan communic potenti serv acceler develop treatment nafld nash
D065626;D006528;D003924;D008113
T047;T191
36,267,566
mir p impair osteogenesi suppress wnt interact lrp co receptor subsequ inhibit akap signal pathway x link hypophosphatemia xlh inherit form ricket caus due mutat phex gene sever factor link diseas aetiolog includ non code rna molecul mirna key post transcript regul gene express play signific role osteoblast function microrna sequenc analysi show differenti regul mirna phex silenc osteoblast cell articl report mir p unidentifi novel mirna function regul osteoblast mir p overexpress impair osteoblast differenti target predict algorithm experiment confirm luciferas utr report assay identifi lrp direct target mir p express mir p osteoblast regul wntbeta catenin signal compon deterior trabecular microarchitectur lead decreas bone format ovariectom ovx mice addit biochem bone resorpt marker like ctx trap b elev serum sampl mimic treat group revers effect observ anti mir treat anim along increas bone format marker pnp moreov transcriptom analysi mir p identifi novel uncharacter akap gene osteoblast cell knock result downregul osteoblast differenti marker transcript translat level overal studi first time report role mir p osteoblast function downstream akap signal regul osteoblastogenesi
D035683;D010012;D054758;D060488
T123;T116;T192;T042;T114
36,267,565
increas level serum adenosin deaminas increas risk diabet peripher neuropathi type diabet increas serum adenosin deaminas ada level shown involv metabol abnorm immun disequilibrium may turn contribut inflammatori diseas studi aim determin whether increas serum ada level relat diabet peripher neuropathi dpn patient type diabet td
D003929;D003924
T047
36,267,563
recent advanc neuropeptid relat omic gene edit spotlight npi somatostatin role growth food intak fish feed growth two close relat import physiolog process live organ studi mammal provid us seri character neuropeptid receptor well role appetit control growth central nervous system especi hypothalamus play import role regul appetit base role regul feed neuropeptid classifi orexigen peptid anorexigen peptid date regul mechan neuropeptid feed growth explor main mammalian model howev lower divers vertebr littl known fish regard knowledg regulatori role neuropeptid receptor recent year develop omic gene edit technolog acceler speed depth research neuropeptid receptor power techniqu tool allow precis comprehens perspect explor function mechan neuropeptid paper review recent advanc omic gene edit technolog neuropeptid receptor progress regul feed growth fish purpos review contribut compar understand function mechan neuropeptid non mammalian especi fish
D009478;D009479
T123;T116
36,267,558
studi influenc green inclus leadership employe green behaviour result implement doubl carbon strategi issu encourag green behaviour becom promin one societi accord cognit affect process system theori studi construct two path green inclus leadership influenc employe green behaviour cognit pathway mediat pro environment goal clariti affect way mediat green organ identif data analysi employe chemic enterpris reveal first employe percept green inclus leadership posit affect employe green behaviour second green inclus leadership enhanc employe awar environment goal green organ identif employe like behav environment furthermor green hrm practic posit moder relationship green inclus leadership pro environment goal clariti well posit moder relationship green inclus leadership green organ identif studi aim provid theoret practic insight promot green develop organ perspect leadership style facilit green develop
D007857;D017132
T078;T082;T054
36,267,557
effect modifi duhuo jisheng decoct combin arthroscop surgeri bone metabol oxid stress serum tlr tgf patient knee osteoarthr analyz effect modifi duhuo jisheng decoct combin arthroscop surgeri bone metabol oxid stress serum tlr tgf patient knee osteoarthr koa
D020370
T047
36,267,556
intellig construct technolog adopt drive strategi china tripartit evolutionari game analysi adopt intellig construct technolog ict regard one import strategi transform upgrad chines construct industri achiev high qualiti develop ict adopt process govern drive subject owner import subject ict appli practic general contractor studi first analys evolutionari process impact particip strategi choic system equilibrium establish tripartit evolutionari game framework includ govern owner general contractor main stakehold test feasibl ration model analys ess correspond three phase ict adopt result show condit ess establish main depend relationship cost benefit stakehold owner sensit govern subsidi penalti general contractor govern establish dynam reward punish mechan base result model high adopt cost key barrier ict adopt owner general contractor paper provid new framework research relat ict adopt refer strateg adjust stakehold ict adopt
D060389
T090
36,267,555
influenc cultur communic psycholog health univers student environ big data progress inform technolog internet technolog mani new media communic technolog also progress univers student forefront develop internet applic cultur communic therefor impact modern cultur communic colleg student obvious time cultur communic reli time communic media affect univers student psycholog cognit experi mental health level univers student high risk group mental health problem present colleg student mental healthi howev consider number student mental health optimist therefor pay attent impact cultur colleg student mental health play import role healthi growth colleg student howev consider number student psycholog health optimist therefor pay attent impact cultur univers student psycholog health play import role healthi growth univers student articl univers student random select subject studi scl test relat factor use investig cover factor five common classif algorithm train train set evalu verif set classifi best effect select algorithm use discern student psycholog health problem test set experipsycholog result show precis reach recal reach f measur reach base influenc factor univers student psycholog health analysi random sampl base famili environ school environ communiti environ inform cultur environ factor articl put forward strategi creat warm progress famili environ friend posit campus environ democrat scientif communiti educ environ civil fair legal environ proper solv psycholog health problem univers student
D008603;D000077558
T170;T041
36,267,554
garden landscap design method public health urban plan base big data analysi technolog aim goal high qualiti develop landscap architectur industri activ promot develop integr digit network intellig technolog promot intellig diversifi develop landscap architectur industri due limit draw design technolog construct method tradit landscap architectur construct realli understand public demand construct scheme also reli experi subject aesthet profession result improp connect design construct present guidanc nation strategi background rapid develop digit technolog g big data cloud comput internet thing digit twin high integr landscap architectur construct digit technolog led transform product mode landscap architectur construct abund profession data conveni inform process platform enabl landscap planner design builder evalu whole life cycl project scientif object realiz digit whole process investig analysi design construct oper mainten landscap architectur industri signific digit technolog chang product tool also updat environment awar design respons construct method make landscap architectur plan design achiev organ combin qualit quantit also make landscap architectur disciplin scientif ration paper new method combin grey relat degre machin learn use provid new guidanc tradit landscap plan use big data inform landscap design achiev good result articl analyz guidanc landscap architectur design big data china provid valuabl refer promot construct landscap architectur china
D000077558;D002958
T064;T170
36,267,553
applic develop mural art urban public environ landscap design gradual improv social econom level citi meet peopl basic live need also artist express certain extent public pay attent beauti extern environ landscap citi settlement landscap character man made landscap cultur resourc also ecolog environ resourc mural also first work art mankind accord record mural largest number artwork china popular work art repres social function histor valu aesthet valu polit signific educ function due great influenc latest technolog emerg technolog urban art concept mural wide use urban public landscap europ america grand strong space coverag wast much space impercept influenc vision make main element urban public art therefor mural design urban public environ improv china current urban atmospher enhanc urban characterist bring citizen histor cultur understand urban environ live enjoy art accord interrelationship citi public environ human mural art base relev theoret knowledg urban plan design urban public art manag base basic characterist human mural art studi combin larg number domest foreign case start characterist natur environ human urban environ articl studi relationship mural design architectur design concept concept urban public environ landscap design
D002958;D004779
T078;T064
36,267,552
sustain trend big data enterpris suppli chain artifici intellig green financi system today rapid develop internet societi enter era inform explos financi data particular import part network inform also reach new level public demand frequent appear word carbon peak green indic transit nation polici field sustain develop sustain develop would becom inevit choic green suppli chain becom new trend polici background suppli chain financ use idea method key suppli manag provid financi servic relat enterpris enterpris acquir organ use inform data suppli chain like outdat even abandon short term paper take artifici intellig green financi system background use cooper theori model analyz predict big data inform enterpris suppli chain realiz transform inform sustain resourc enterpris releas huge potenti big data model model help compani overal profit increas also provid scientif support corpor decis make promot develop compani
D000077558;D001185
T090;T170;T073;T066
36,267,540
updat novel ocular nanosystem possibl benefit treatment corneal neovascular corneal neovascular cnv ocular patholog chang result imbal angiogen factor antiangiogen factor result various ocular insult includ infect inflamm hypoxia trauma corneal degener corneal transplant current clinic strategi treatment cnv includ pharmacolog treatment surgic intervent despit degre success current treatment strategi restrict limit efficaci advers effect short durat action recent gene base antiangiogen therapi becom emerg strategi attract consider interest howev potenti complic use viral vector potenti genotox result long term express nonspecif target ignor use ocular nanosystem on base nanotechnolog emerg great advantag ocular diseas treatment last two decad potenti function on rang nanocarri deliv drug gene target site eye therapeut agent various preclin studi conduct date demonstr promis result use on treatment cnv review provid overview cnv current therapeut strategi summar properti applic various on relat treatment cnv report date goal provid comprehens review consider advanc on field cnv therapi past two decad fill gap previous relat report final discuss exist challeng futur perspect use on cnv therapi goal provid theoret contribut facilit futur practic growth area
D016510
T047
36,267,465
elev mfg e csf earli stage indic rapid recoveri mild aneurysm sah patient aneurysm subarachnoid hemorrhag asah impair blood perfus brain tissu caus advers effect microglia inher immun cell brain signific activ play role phagocytosi anti inflammatori proinflammatori damag repair process milk fat globul epiderm growth factor mfg e bridg molecul process mediat activ biolog effect microglia
D000954;D008894;D013345
T129;T123;T116;T047;T046
36,267,464
age associ transcriptom alter peri implant patholog bioinformat studi age associ increas incid peri implant role age associ biolog mechan occurr peri implant known studi aim perform integr bioinformat analysi public avail dataset uncov molecular mechan relat age peri implant
D019295;D057873
T047;T091
36,267,463
sn sensit brca profici ovarian cancer parp inhibitor inhibit homolog recombin repair multifunct protein posttransl modif enzym eukaryot cell poli adp ribos polymeras parp act dna damag sensor help repair dna damag recruit repair protein dna break site parp inhibitor offer signific clinic benefit ovarian cancer brca mutat howev major ovarian cancer patient harbor wild type wt brca status narrow clinic applic identifi small compound sn cpt analog sensit brca profici ovarian cancer cell parp inhibitor treatment inhibit homolog recombin hr repair sn treatment great enhanc parp inhibitor olaparib induc dna doubl strand break dsbs dna replic stress meanwhil combin sn olaparib synergist induc apoptosi ovarian cancer furthermor combin administr sn olaparib induc synergist antitumor efficaci ovarian cancer xenograft model vivo therefor studi provid novel therapeut strategi optim parp inhibitor therapi patient brca profici ovarian cancer
D010051;D000970
T121;T191;T109
36,267,462
activ transcript factor base earli alarm model acut kidney injuri cardiopulmonari bypass adult acut kidney injuri aki common complic cardiopulmonari bypass cpb cardiac surgeri effect treatment studi aim construct earli warn model aki cpb adult investig perform model patient underw cpb depart cardiac surgeri shanghai tenth peopl hospit januari decemb recruit present studi blood urin sampl collect preoper h h h h h h surgeri creatinin activ transcript factor atf detect accord diagnost criteria aki patient divid aki group non aki group risk factor aki cpb screen receiv oper characterist roc curv analysi use identifi optim biomark establish earli warn model aki cpb final perform model verifi total patient includ studi develop aki surgeri cpb serum urin level creatinin atf increas differ degre increas urin atf obvious aki group area roc auc urin atf h surgeri ci atf higher pgml sensit specif atf diagnosi aki respect height conjug bilirubin surgeri day urin atf h surgeri serum creatinin h surgeri independ risk factor postop aki urin atf factor use establish aki warn model cpb show good fit accuraci conclus atf earli biomark post cpb aki addit urin atf aki risk factor improv accuraci earli aki predict
D002315;D058186
T061;T047;T037
36,267,461
analysi bmp associ modif immun infiltr pancanc research explor under link diagnosi therapi bone morphogenet protein bmp various cancer
D056915;D009369
T045;T191;T086
36,267,460
neutrophil lymphocyt ratio biomark predict coronari arteri abnorm kawasaki diseas meta analysi conduct systemat review meta analysi relationship neutrophil lymphocyt ratio nlr coronari arteri abnorm caa patient kawasaki diseas kd accord prefer report item systemat review meta analys prisma statement search pubm scopus web scienc embas trip googl scholar proquest th august done retriev elig studi date languag limit consid studi methodolog qualiti assess conduct accord newcastl ottawa scale nos standard mean differ smd confid interv ci use depict pool continu variabl final articl kd patient develop caa enrol meta analysi nlr level signific higher kd patient caa compar without caa smd ci p addit nlr level signific higher patient coronari arteri aneurysm without coronari arteri aneurysm smd ci p howev signific associ nlr coronari arteri dilat observ meta analysi smd ci public bias pool smd nlr coronari arteri abnorm kd egger test p begg test p nlr may use monitor caa develop patient may impli mechanist role potenti inflamm mediat process
D009080;D003324;D000783
T047;T046;T190
36,267,459
low prognost nutrit index contribut high advers event preeclampsia preeclampsia pe common obstetr complic caus signific harm pregnant mother clinic signific poor nutrit status pe patient unclear aim studi evalu nutrit status measur prognost nutrit index pni score admiss abil predict hospit advers event patient pe
D015596;D011225
T060;T081;T170;T046
36,267,458
ferul acid mitig growth invas esophag squamous cell carcinoma induc ferroptot cell death ferroptosi iron ros depend form cell death initi lipid peroxid rapid develop studi ferroptosi facilit applic cancer therapeut current studi aim investig function properti ferul acid fa phenol acid substanc induc ferroptosi antiesophag squamous cell carcinoma escc
D000077277;D004938;D000079403
T191;T043
36,267,440
impact covid pandem depress symptom china longitudin popul base studi object aim examin covid incid associ depress symptom china whether associ transient whether associ differ across group method use longitudin sampl wave china famili panel studi construct covid incid rate number new case per popul respond resid provinc past day respond survey perform linear logist regress examin associ perform stratifi analys explor heterogen associ result sampl includ adult day incid rate posit associ ces score coef ci likelihood depress adjust odd ratio ci associ larger among less educ pre exist depress chronic condit find signific associ day local incid rate depress symptom conclus impact covid incid mental health china general popul statist signific moder magnitud transient disadvantag group experienc higher increas depress symptom
D000086382
T047;T067
36,267,326
impact spirometr confirm chronic obstruct pulmonari diseas arteri stiff surfact protein percutan coronari intervent catepoc studi sever mechan propos explain chronic obstruct pulmonari diseas copd impair prognosi coronari event aim explor copd variabl relat wors prognosi patient undergo percutan coronari intervent pci
D062645;D029424;D037663;D059289
T061;T123;T116;T047;T046
36,267,325
il promot epitheli adam express cigarett smoke relat copd report disintegrin metalloproteinas adam involv pathogenesi cigarett smoke cs associ chronic obstruct pulmonari diseas copd cs exposur lead upregul adam remain unknown
D029424;D000073865
T055;T047
36,267,319
analysi influenc midwif led antenat clinic deliveri outcom primipara evalu medic data order improv comprehens effect primipara deliveri outcom midwif led prenat clinic data mine analyz allevi negat emot patient improv deliveri result patient
D008880;D007743
T040;T091;T097
36,267,318
influenc narcotrend assist anesthesia depth monitor cognit impair elder patient general anesthesia research design probe influenc narcotrend nt assist anesthesia depth monitor cognit impair elder patient general anesthesia ga
D060825;D000777
T121;T039;T048
36,267,317
clinic characterist treatment adult idiopath carpal tunnel syndrom accompani trigger digit investig clinic characterist treatment adult idiopath carpal tunnel syndrom cts accompani trigger digit
D002349;D052582
T047;T020
36,267,316
compar studi featur select protein structur function predict mani effect method extract fuse differ protein featur studi relationship protein sequenc structur function differ method prefer solv research protein structur function requir select valuabl contribut featur design effect predict method work main focus featur select method studi protein structur function systemat compar analyz effici differ featur select method predict protein structur protein disord protein molecular chaperon protein solubl result show featur select method base nonlinear svm perform best protein structur predict protein solubl predict protein molecular chaperon predict protein solubl predict select accuraci featur improv especi kmer featur pssm featur protein
D011506
T123;T116
36,267,315
effect quadrupl therapi combin probiot helicobact pylori relat peptic ulcer present studi design observ effect quadrupl therapi combin probiot helicobact pylori relat peptic ulcer patient control group n given regular quadrupl therapi includ proton pump inhibitor ilaprazol enter coat tablet two antibiot amoxicillin dispers tablet metronidazol tablet colloid bismuth pectin capsul week patient studi group n given abovement quadrupl therapi combin probiot live combin bifidobacterium lactobacillus enterococcus capsul oral week hp clearanc rate recurr rate level gastrointestin hormon maker advanc reaction two group compar nd week treatment helicobact pylori clearanc rate studi group signific higher control group total recurr rate studi group signific lower control group p serum gastrin motilin express lower somatostatin express signific higher control group p summari quadrupl therapi combin probiot treatment helicobact pylori relat peptic ulcer improv helicobact pylori clearanc rate reduc helicobact pylori recurr rate benefici improv level gastrointestin hormon certain safeti
D016480;D016481;D010437;D019936
T047;T007
36,267,314
diagnost valu ct window techniqu primari omentum infarct diagnost valu ct window width techniqu primari omentum infarct evalu studi
D014057;D009852
T060;T023
36,267,313
construct valid prognost model base mrnasi relat gene breast cancer breast cancer big threat women across world substanti morbid mortal press matter studi establish prognost gene model breast cancer base mrnasi predict patient prognost surviv
D001943
T191
36,267,312
edta combin c pilot file microultrasound root canal calcif dredg effect safeti analysi paper discuss dredg effect safeti ethylenediaminetetraacet acid edta combin c pilot file microultrasound mus root canal calcif
D002114;D018915
T061;T047;T046
36,267,311
construct colorect cancer prognost risk model screen prognost risk gene use machin learn algorithm studi aim construct prognost risk model colorect cancer crc use machin learn algorithm provid accur stage screen credibl prognost risk gene extract crc data gse gse gene express omnibus geo databas dataset tcga analyz differenti express gene deg use bioinformat analysi among share deg relat crc prognosi divid analysi period differ phase appli univari cox regress lasso multivari cox regress analysi go analysi kegg analysi reveal function deg primarili focus cell cycl dna replic cell mitosi relat function confirm result biolog perspect final prognost risk model crc base chga clu plk axin nrc ilrb gcg ajuba gene construct risk score enabl us predict prognosi crc obtain comprehens accur model use intern extern evalu model abl correct differenti patient crc high risk group poor prognosi low risk group good prognosi auc valu year surviv roc curv respect accord intern evalu auc valu respect extern evalu use gse geo databas determin clu plk ilrb could consid independ prognost factor crc signific differ express p use machin learn method prognost risk model compris eight gene construct model provid improv treatment guidanc also provid novel perspect analyz surviv condit deeper biolog level
D060066;D015179
T191;T169
36,267,310
analysi effect communic abil nurs outpati infus room treatment experi patient famili observ effect nurs communic abil outpati infus room treatment experi outpati famili analyz whether improv nurs communic skill reduc incid doctor patient disput
D010045;D003142
T080;T170;T054;T097;T101
36,267,309
effect nurs outcom orient intervent airway manag elder long term bedridden patient studi intend explor nurs outcom orient intervent effect airway manag elder long term bedridden patient
D011788;D000075482
T078;T101
36,267,308
fatigu detect air traffic control base fuzzi fusion multipl featur fatigu detect air traffic control import yet challeng problem aviat safeti research exist method problem base facial featur paper propos ensembl learn model combin facial featur voic featur design fatigu detect method multifeatur fusion refer facial voic stack fv stack specif facial featur first use opencv dlib librari extract mouth eye area employ combin convolut neural network cnn e convolut neural network e cnn determin state mouth eye closur base five featur ie blink time averag blink time averag blink interv percentag eyelid closur pupil time perclo frequenc open mouth fom voic featur extract mel frequenc cepstral coeffici mfcc featur speech facial featur voic featur fuse care design stack model fatigu detect real life experi conduct air traffic control southwest air traffic manag bureau civil aviat china result show propos fv stack method achiev detect accuraci best accuraci achiev singl model best accuraci achiev state art detect method
D014831
T040
36,267,307
mir p atm express esophag squamous cell carcinoma correl clinicopatholog featur investig mir p ataxia telangiectasia mute atm express esophag squamous cell carcinoma escc correl clinicopatholog featur
D000077277;D004938;D001260;D035683
T123;T047;T191;T114
36,267,306
evalu clinic status endoscop retrograd cholangiographi placement metal plastic stent cholangiocarcinoma therapi cholangiocarcinoma common malign tumor occur bile duct system treat use endoscop retrograd cholangiographi ercp studi aim explor therapeut effect ercp metal stent plastic stent cholangiocarcinoma
D001650;D018281
T191
36,267,305
studi risk factor relat intrauterin adhes base meta analysi intrauterin adhes iua sever complic occur follow abort evalu relat risk factor uterin caviti adhes meta analysi
D014591
T047
36,267,304
low dose x ray increas paracellular permeabl human renal glomerular endotheli cell glomerular endothelium function filtrat barrier metabolit kidney although x ray irradi modul permeabl vascular endothelium respons human renal glomerular endotheli cell hrgec low dose x ray irradi investig evalu impact low dose x ray irradi hrgec reveal under mechan
D042783;D014343
T130;T025;T109
36,267,303
investig clinic effect new shoulder joint abduct frame humer fractur patient arthroscop shoulder surgeri work organ analyz clinic effect new shoulder joint abduct frame bone metabol marker shoulder joint function visual analogu scale vas humer fractur patient undergo arthroscop surgeri
D006810;D012784;D012785
T023;T037;T030
36,267,302
identif prognost fatti acid metabol lncrnas potenti molecular target drug uveal melanoma aim studi identifi prognost fatti acid metabol lncrnas potenti molecular target drug uveal melanoma integr bioinformat analysi
D062085
T123;T114
36,267,243
crosstalk gut brain ischem stroke mechanist insight therapeut option signific amount interest past two decad studi evolut gut microbiota intern extern impact gut risk factor cerebrovascular disord cerebr ischem stroke network bidirect communic gut microorgan host known microbiota gut brain axi mgba mount evid maintain gut microbiota homeostasi frequent enhanc effect ischem stroke treatment modul immun metabol inflammatori respons mgba effect monitor cure ischem stroke restor healthi microbi ecolog gut may critic therapeut focus review highlight mechanist insight mgba diseas pathophysiolog review summar role mgba signal develop stroke risk factor age hypertens obes diabet atherosclerosi well chang microbiota experiment clinic popul addit review also examin dietari chang administr probiot prebiot fecal microbiota transplant treatment option ischem stroke potenti health benefit becom appar mgba affect human health diseas continu advanc emerg field biomed scienc
D000083242;D019936;D020521
T047;T007
36,267,028
reproduc robust motor cortic stimul assess muscl relax kinet transcrani magnet stimul tms motor cortex use voluntari contract inhibit corticospin drive muscl consequ induc involuntari muscl relax aim evalu reproduc effect vari experiment condit robust tms induc muscl relax relax deep finger flexor assess healthi subject f use handgrip dynamometri normal peak relax rate main outcom measur peak relax rate divid voluntari plus tms evok forc prior relax interday interrat reliabl relax rate high intraclass correl coeffici coeffici variat respect target forc maxim voluntari forc higher result similar relax rate maxim stimul output higher relax rate remain later posit cm vertex render lower relax rate mean sd ci compar stimul vertex ci within rang baselin skin temperatur averag chang normal peak relax rate measur per c chang skin temperatur conclus interday interrat reproduc reliabl tms induc muscl relax finger flexor high furthermor techniqu robust limit effect target forc stimul intens coil posit muscl relax strong affect skin temperatur howev effect margin within normal skin temperatur rang deem techniqu well suit clinic scientif assess muscl relax
D009044
T023;T029
36,266,992
current status nuclear cardiolog practic latin america caribbean era multimod cardiac imag approach updat cardiovascular diseas cvds lead caus mortal latin america caribbean lac risk men slight higher women coronavirus diseas covid pandem caus signific reduct number cardiac diagnost procedur global particular lac nuclear cardiolog avail region variabl term exist technolog radiopharmaceut human resourc region singl photon emiss comput tomographi spect pet scanner argentina brazil largest number increas number new technolog cadmium zinc tellurid czt cardiac dedic gamma camera spectcomput tomographi ct petct countri perform myocardi perfus imag studi main gate spect rest multi gate acquisit main cardiac toxic detect viabil rest gate spect patient dilat cardiomyopathi bone avid tracer cardiac scintigraphi transthyretin cardiac amyloidosi diagnosi regard non nuclear cardiac imag modal argentina colombia chile highest ratio ct scanner brazil argentina chile show highest ratio mri scanner develop nuclear cardiolog advanc imag modal challeng high cost equip lack equip mainten servic insuffici specif train imag specialist refer clinician lack awar cardiologist refer physician clinic applic nuclear cardiolog anoth import aspect consid necess implement cardiac imag multimod train joint work nuclear medicin specialist radiologist cardiologist clinician general mandatori achiev goal nation region intern cooper includ support scientif profession societi american societi nuclear cardiolog latin american associ biolog nuclear medicin societi cardiolog societi organ intern atom energi agenc pan american health organ well govern commit key factor overal effort tackl burden cardiovascular diseas region
D002318;D000086382;D002309;D055414
T060;T047;T091;T067
36,266,987
toll like receptor agonist poli c flagellin lead il induct diverg releas kinet differenti alter autophagi primari human keratinocyt il pro inflammatori member il cytokin superfamili induc secret normal human foreskin keratinocyt hfks respons pathogen stimuli howev mechan under secret unknown studi demonstr stimul tlr agonist poli c led delay secret il compar stimul tlr agonist flagellin despit equal level cytokin p il shown releas hfks inact uncleav form base western blot moreov recombin il activ cleav form induc endogen il fold p cxcl five fold p baselin level compar unactiv full length recombin il ratio lcb iilcb signific higher poli c treat cell compar flagellin treat unstimul control without chang sqstmp hour stimul p fluoresc microscopi poli c led two fold increas eight hour four fold increas hour accumul autophagosom post stimul p contrast autophagosom unchang relat baselin respons flagellin bafilomycin treatment enhanc poli c mediat il secret p rapamycin led notic non signific increas flagellin mediat il secret indic interrupt autophag flux alter il greleas hfks final show compar clinic normal laryng tissu signific higher level lcb ii hpv infect respiratori papilloma tissu indic higher number autophagosom signatur disrupt autophag flux
D005408;D007375
T129;T123;T116
36,266,986
associ interleukin recurr pregnanc loss egyptian women success pregnanc requir distinct complex immunolog state cytokin appear critic establish tolerogen environ toward semi allogen foetus foeto matern interphas shift th th cytokin profil may crucial imbal cytokin signific factor recurr pregnanc loss rpl interleukin il member il cytokin famili involv innat adapt immun respons coordin immun cell function broad rang physiolog patholog process includ regul pregnanc outcom
D000067596;D000026
T129;T047;T116
36,266,985
th cytokin endotyp discrimin predict sever complic covid treatment sever critic case coronavirus diseas covid still top prioriti public health previous report distinct th cytokin relat pathophysiolog sever covid condit present studi investig associ th th cytokinechemokin endotyp cell mediat immun via multiplex immunophenotyp singl cell rna seq analysi peripher blood mononuclear cell analysi clinic featur covid patient base serum cytokin system inflammatori marker covid case classifi four cluster increas iv sever two promin cluster interest could use prognost refer target treatment sever covid case cluster iii reflect severecrit patholog character decreas ccl level increas il c reactiv protein cxcl il il level second cluster cluster ii show mild moder patholog character predomin cxcl il level level il crp relat low cluster ii patient receiv anti inflammatori treatment earli stage may led prevent diseas prognosi accompani il crp induct cluster iii decreas proport effector cell sign cell exhaust observ studi highlight mechan endotyp cluster base specif inflammatori marker relat clinic outcom covid
D016207;D000086382
T129;T047;T116;T067
36,266,980
ral hernndez snchez group fun eat pizza pizza parti becom ritual everi time good news group alway good mood see babi daughter smile find ral hernndez snchez introduc profil
D005502
T168
36,266,977
solar driven catalyt urea oxid environment remedi energi recoveri invit month cover group chong peng shanghai jiao tong univers imag show solar driven catalyt urea convers interconnect sustain develop energi environ review avail cssc
D052918;D012993
T070;T069
36,266,937
brain abscess caus nocardia farcinica year old woman multipl myeloma rare case review literatur background central nervous system infect nocardia speci associ high morbid mortal occurr patient multipl myeloma rare acquisit infect patient associ use novel therapeut agent eg bortezomib lenalidomid bone marrow transplant report first case nocardia brain abscess patient multipl myeloma without risk factor case report year old woman igg kappa type multipl myeloma present general tonic clonic seizur magnet reson imag brain reveal space occupi lesion left frontal left pariet right pariet region craniotomi enucl left frontal lesion reveal abscess cultur result nocardia farcinica patient treat meropenem amikacin trimethoprim sulfamethoxazol week follow trimethoprim sulfamethoxazol month good outcom conclus cerebr nocardiosi rare entiti occurr case may hint toward myeloma associ humor immun dysfunct pathogenesi import humor immun defens infect howev chemotherapi induc cell mediat dysfunct rule risk factor infect despit rariti case aim rais awar condit reiter import consid rare life threaten condit differenti diagnosi brain lesion especi misdiagnosi radiolog find occur previous case avoid delay appropri surgic medic treatment affect outcom
D009101;D009615;D009617;D001922;D000970
T121;T007;T109;T191;T047
36,266,935
distribut determin plasma homocystein level preconcept popul retrospect singl center studi background rais plasma homocystein hci level associ various diseas pregnanc complic preconcept primari prevent period prevent birth defect retrospect studi aim investig distribut plasma hci level among men women preconcept evalu factor influenc plasma hci level southern china popul materi method sex age serum folat level plasma hci level time hci folat detect obtain medic record univari analysi multi factor mix virtual linear regress use explor distribut determin plasma hci level result total particip men women includ averag level hci rate hyperhomocysteinemia hhci men higher women p hci level observ lowest autumn highest winter p normal hci nhci group serum folat level higher hhci group p regress analysi suggest sex season serum folat level effect hci level age influenc factor hci level preconcept popul conclus retrospect studi show hci level higher men winter season sex season serum folat level influenc factor hci preconcept popul
D005492;D020138
T121;T047;T127;T109
36,266,851
direct measur aerotact respons bacteri suspens aerotaxi abil motil cell navig toward oxygen key question depend aerotact veloc local oxygen concentr c combin simultan bacteria track local oxygen concentr measur use ruthenium encapsul micell character aerotact respons burkholderia contaminan motil bacterium ubiquit environ experi oxygen gradient produc bacteri respir seal glass capillari permeabl oxygen one end produc bacteri band travel toward oxygen sourc comput aerotact respons c popul scale drift veloc bacteri band bacteri scale angular modul run time method consist power law c good agreement exist model base biochemistri bacteri membran receptor
D012428
T196
36,266,823
proven life chemic autonom agent surviv associ learn present benchmark studi autonom chemic agent exhibit associ learn environment featur associ learn system wide studi cognit scienc artifici intellig common implement high complex care engin system anim brain artifici neural network dna comput system gene regulatori network among other abil encod environment inform use make simpl predict benchmark biolog resili underpin plethora adapt respons live hierarchi span prey anim speci anticip arriv predat epigenet system microorgan learn environment correl given ubiquit essenti presenc learn behavior biospher aim explor whether simpl nonliv dissip structur could also exhibit associ learn inspir previous model associ learn chemic network simul simpl system compos long short term memori chemic speci could encod presenc absenc tempor correl two extern speci abil learn associ implement gray scott reaction diffus spot emerg chemic pattern exhibit self replic homeostasi novel abil associ learn demonstr simpl chemic pattern exhibit broad repertoir lifelik behavior pave way vitro studi autonom chemic learn system potenti relev artifici life origin life system chemistri experiment realize learn behavior protocel coacerv system could advanc new research direct astrobiolog sinc system signific reduc lower bound requir complex autonom chemic learn
D001185;D016571
T090;T170;T073;T066
36,266,790
mosquito popul human social behavior spatial explicit agent base model mosquito vector diseas transmiss human popul aed aegypti main vector dengu argentina main breed artifici contain strong adapt urban environ highlight relev understand human social behavior design success vector control campaign develop model mosquito popul consid main biolog behavior featur incorpor paramet model human behavior relat water contain dispos perform extens numer simul studi variabl adult aquat mosquito popul various protocol appli chang effect frequenc water bucket dispos delay avail water contain breed found effect threshold valu possibl signific limit mosquito dispers interest nonsynchron discard frequenc attain human popul effici synchron one reduc aquat mosquito popul scenario random delay avail water contain indic decis fix time delay entir popul realist mimic wider rang human behavior simpl model could help design dengu prevent campaign aim mosquito popul control
D000330;D003715
T047;T204
36,266,773
revers phase transform zeolit imidazol framework membran separ util revers phase transform rpts metal organ framework creat materi divers also promis self restor crystal control manner howev limit exampl seek conveni effect trigger rpts especi rpts respect spatiotempor harmoni cleavag reconstruct metal linker chemic bond challeng work found zeolit imidazol framework zif zn n coordin bond show moder strength ideal platform report three crystal phase zif name sodalit sod diamondoid dia larg poresodalit lpsod topolog identifi rpts phase expos water water vapor sod structur could transform compact dia version result decomposit four member ring synchron reorgan six member ring dia structur could also return back sod soak dimethylformamid dmf dmf vapor high temperatur treatment sod give rise lpsod revert sod dmf lpsod could also compress dia phase water water vapor restor via two step treatment name soak dmf dia sod right high temperatur therapi sod lpsod perspect separ util found lpsod version zif relat sod structur zif produc mix matrix membran interest interfaci structur polym chain though share chemic composit verifi larg pore lpsod allow penetr polym chain contribut reinforc bi phase interfac also sharpen molecul siev properti filler toward co ch
D017641
T197
36,266,768
impact advanc practic provid characterist qualiti care patient chronic hepat b advanc practic provid app may abl play role improv linkag care patient chronic hepat b chb data limit
D019694
T047