Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,266,763	brain target near infrar nanobeacon situ monitor h fluctuat epilept seizur epilepsi neurolog brain diseas recurr seizur relat reduct substanc power antioxid defens system ad howev report studi situ antioxid fluctuat epilepsi vari sever work hydrogen sulfid h select model target h respons near infrar fluorophor design synthes amphiphil molecul synthes modifi angiopep peptid hydrophil terminus nanobeacon term bfpp prepar format micell packag fluorophor nanobeacon sensit h low detect limit nm h fluctuat cell monitor fluoresc imag addit angiopep peptid surfac bfpp help cross blood brain barrier near infrar fluoresc improv vivo imag bfpp reveal h moder level normal brain level obvious elev mild epilepsi activ ad signific suppress sever epilepsi due neuron damag approach general access target alter respons fluorophor signific situ analysi brain patholog	D006862;D004827	T131;T197;T033;T047;T130
36,266,731	circlrfn inhibit progress glioblastoma via prrxgch mediat ferroptosi ferroptosi novel form iron depend cell death particip malign progress glioblastoma gbm although circular rnas circrna found play key role ferroptosi via sever mechan includ regul iron metabol glutathion metabol lipid peroxid mitochondri relat protein mani novel circrna regul ferroptosi need found may becom new molecular treatment target gbm	D001932;D000079403;D005909;D005910;D000079962	T191;T114;T043
36,266,729	spontan ruptur larg splenic arteri aneurysm year old male patient pemphigus vulgari case report current inform anatom risk factor splenic arteri aneurysm ruptur specif locat size lesion therefor report entiti obtain data ultim reduc morbid mortal essenti report case male patient spontan ruptur larg splenic arteri aneurysm present abdomin pain	D010392;D017542;D013161;D005767	T047;T037
36,266,728	pdcd inhibit progress renal cell carcinoma promot cell immun involv hdacmicrorna psgk epigenet exert vital role onset develop renal cell carcinoma rcc mount evid shed light signific human immun system respons tumor infiltr cell herebi sought unmask immunomodulatori role histon deacetylas hdac potenti upstream molecul program cell death pdcd rcc	D051017;D002292;D007680;D035683;D009363	T123;T191;T116;T114
36,266,727	lung resect surgeri jehovah wit patient year singl center experi pauciti literatur surgic outcom jehovah wit jw patient undergo lung resect suggest patient oper lung cancer may deni resect aim studi better understand periop outcom long term cancer surviv jw patient undergo lung resect	D002289;D008175;D033221	T098;T191
36,266,726	casa comprehens databas resourc covid altern splice atlas key process transcript regulatori mechan altern splice play crucial role maintain divers rna protein express mediat immun respons infecti diseas especi covid therefor urgent data gather research profil microb infect human cell need improv understand covid relat infecti diseas herein creat casa covid altern splice atlas provid conveni comput platform studi covid covid relat infecti diseas	D017398;D000086382	T123;T067;T045;T114;T047
36,266,725	novel pathogen variant cubn uncoupl proteinuria renal function proteinuria unfavor clinic condit high associ risk renal cardiovascular diseas chronic kidney diseas ckd howev whether proteinuria form link renal impair still unclear cubilin endocyt receptor high express renal proxim tubul mediat uptak albumin transferrin microglobulin	D007668;D011507	T033;T023
36,266,721	hpv e alter transles synthesi signal subset human papillomavirus hpvs caus virtual everi cervic cancer call high risk hpvs encod two major oncogen hpv e e necessari transform among high risk hpvs hpv caus cervic cancer often use repres model oncogen hpvs hpv e oncogen facilit hpv lifecycl bind destabil rb ensur virus access cellular replic machineri rb destabil increas ef respons gene express caus replic stress hpv e mitig deleteri effect associ replic stress degrad p cell undergo separ adapt toler stress demonstr includ activ transles synthesi tls pathway prevent replic stress caus replic fork collaps show signific elev tls gene express common cervic cancer cancer type analyz addit increas tls protein abund hpv e express cell reduc abil induct critic tls factor pol respons replic stress induc agent final show increas express least one tls gene associ improv surviv women cervic cancer	D002583;D050725	T123;T191;T116
36,266,719	prognosi relat nutrit score cancer patient prns clinic nutrit score deriv retrospect cohort studi nutrit assess qualiti life qol becom import indic therapeut efficaci patient malign aim develop valid easi use questionnair prognost valu assess nutrit status hospit cancer patient	D009369;D011788	T078;T191
36,266,718	effect capit polici withdraw matern health servic provis ashanti region ghana interrupt time seri analysi payment method known influenc matern care deliveri health system ghana suspend pilot capit provid payment system near five year implement studi aim examin effect ghana capit polici matern health care provis part lesson learn bridg critic literatur gap	D008427	T058
36,266,717	reprogram sentinel lymph node microenviron tumor metastasi metastasi major caus death patient cancer two main rout cancer cell dissemin blood lymphat system under mechan hematogen metastasi well character past decad howev understand molecular basi lymphat metastasi remain prematur stage conceptu cancer cell invad lymphat capillari passiv move collect lymphat vessel migrat sentinel lymph node sln first lymph node cancer cell spread primari tumor enter blood circulatori system via subclavian vein arriv cancer cell releas specif solubl factor modul microenviron sln establish beachhead success colon colon cancer cell inhibit anti tumor immun induc recruit regulatori cell myeloid deriv suppressor cell suppress function dendrit cell cd cell promot releas immunosuppress cytokin develop novel strategi revers cancer cell trigger sln remodel may activ immun reduc beachhead buildup distant metastasi addit microanatom locat metastasi sln also import site immun modul nanotechnolog base approach deliv lymph node tropic antibodi drug conjug nanoparticl kill cancer cell site new direct cancer treatment convers induct stronger immun promot antigen present lymph node provid altern way enhanc efficaci immun checkpoint therapi cancer vaccin review articl summar recent find reprogram sln lymphat invas discuss possibl inhibit tumor metastasi elicit anti tumor immun target sln	D000071036;D019496;D001943	T129;T121;T116;T191;T023
36,266,716	whether individu dose escal recommend lymph node differ size definit radiotherapi cervic cancer dose escal posit node mayb improv region control patient node posit cervic cancer optim dose node differ size remain controversi purpos studi explor individu dose escal lymph node lns differ size definit radiotherapi cervic cancer	D002583	T191
36,266,715	influenc year nuss bar placement bar remov case report nuss bar common use minim invas correct pectus excavatum usual remov within year report case year bar placement nuss procedur accompani uniqu complic thorac malform describ asymmetr pectus carinatum caus bar displac signific rib periost hyperplasia describ first time	D005660	T019
36,266,714	factor associ mother health care seek behaviour childhood fever burkina faso find repeat cross section household survey fever one frequent reason paediatr consult burkina faso health care seek behaviour factor associ health care seek event childhood fever poor document studi aim analys health care seek behaviour factor associ health care seek childhood fever burkina faso	D009035;D010342	T080;T092;T099;T055;T058
36,266,713	endoscop combin intraren surgeri prone split leg posit versus galdakao modifi supin valdivia posit manag partial staghorn calculi evalu compar outcom ecir treatment partial staghorn renal calculi prone split leg posit versus gmsv posit regard technic aspect success rate oper time complic safeti effect approach	D000069856;D009403;D007669	T061;T047
36,266,712	determin affect utilis health servic treatment children rural nepali health centr cross section studi larg inequ child health remain nepal cast ethnic sex major determin depriv negat outcom purpos studi explor whether key demograph associ health seek behaviour utilis health care treatment receiv	D010342;D011014	T050;T080;T055;T047;T058
36,266,711	innov approach monitor perform integr diseas surveil respons ebola outbreak sierra leon lesson field supervis healthcar worker improv perform done support object manner regular supervis support function integr diseas surveil respons idsr strategi allow systemat monitor idsr implement start develop partner support ministri health sanit moh revit idsr sierra leon monitor progress support supervis assess report find assess	D019142	T047
36,266,710	develop novel dna marker speci discrimin fasciola fluke base fatti acid bind protein type gene multiplex polymeras chain reaction pcr pcr restrict fragment length polymorph rflp nuclear phosphoenolpyruv carboxykinas pepck polymeras delta pold respect use differenti fasciola hepatica f gigantica hybrid fasciola fluke howev discrimin error report method studi aim develop multiplex pcr base novel nuclear marker fatti acid bind protein type fabp type gene	D005209;D005211	T047;T204
36,266,709	preval factor associ postpartum pelvic girdl pain among women poland prospect observ studi pelvic girdl pain pgp type pregnanc relat lumbopelv pain studi aim examin preval sever factor associ postpartum pgp select group postpartum women poland	D059388;D011248	T033;T047;T046
36,266,708	intervent address potenti inappropri prescript counter medic use among adult year older primari care set protocol systemat review inform recommend canadian task forc prevent health care potenti inappropri prescrib counter otc medic use among adult age year older primari care set protocol outlin plan scope method systemat review benefit harm accept intervent reduc potenti inappropri prescript otc medic use	D057970;D011788	T078;T058
36,266,707	homemad pin hook surgic treatment posterior cruciat ligament avuls fractur treat posterior cruciat ligament pcl tibial insert small comminut avuls fractur still challeng studi evalu clinic radiolog outcom orif pcl tibial insert avuls fractur invert l shape postero medial approach use homemad pin hook	D016119;D000071562;D013978;D018460	T023;T037
36,266,705	blacksmith approach strategi teach learn medic anatomi cours qualit studi anatomi symbol essenti core topic one fundament pillar medic paramed knowledg nevertheless exploratori data analys focus student approach learn anatomi studi examin student perceiv learn experi anatomi lesson make model promot meaning learn profession ident	D013337;D004504;D000715	T065;T091;T097
36,266,704	role model covid pandem mathemat statist model play import role analysi data covid import track progress pandem understand spread popul perhap signific forecast futur cours pandem evalu potenti polici option articl describ type model use research team israel present assumpt basic element illustr use influenc decis articl grew modelist dialog organ israel nation institut health polici research particip leader local model effort	D000086382	T047;T067
36,266,703	five year experi valu base qualiti improv team key factor success implement hospit care recent year valu base healthcar vbhc becom one accept concept fix broken healthcar system numer hospit embrac vbhc tri implement valu base qualiti improv vbqi practic howev lack knowledg practic implement vbhc organ differ approach aim studi explor main factor experienc hinder andor support implement vbqi team hospit care	D058996;D003695	T058;T093;T057
36,266,701	systemat review distribut take home naloxon low middl incom countri barrier implement take home naloxon program opioid overdos epidem hit record high worldwid account mortal relat substanc use take home naloxon thn strategi implement mani develop countri suffer high opioid overdos death rate aim provid overdos identif naloxon administr train along thn deliveri opioid user other like wit overdos incid famili member peer howev littl known measur low middl incom countri lmic opioid use opioid relat death report high systemat literatur review aim examin distribut thn lmic review studi identifi barrier implement thn program worldwid assess applic lmic	D000083682;D062787;D009293	T037;T048
36,266,700	understand perspect recruit key improv randomis control trial enrol qualit evid synthesi recruit patient randomis control trial rcts often report challeng evid base effect intervent could use staff recruit undertak recruit lack although experi perspect recruit wide report evid synthesi requir order inform develop futur intervent paper aim address systemat search synthesis evid recruit perspect experi recruit patient rcts method qualit evid synthesi qes follow thoma harden approach themat synthesi conduct ovid medlin cinahl embas psycinfo cochran central regist control trial orrca web scienc electron databas search studi sampl ensur focus research align phenomena interest qes methodolog relev qes question includ variat across clinic area studi grade cerqual framework use assess confid review find	D006282;D001291	T041;T097
36,266,699	causal genet determin metabolit anxieti disord two sampl mendelian random studi although anxieti disord one preval mental disord under biolog mechan yet fulli elucid recent year genet determin metabolit gdms use reveal biolog mechan mental disord howev strategi appli anxieti disord herein explor causal gdms anxieti disord mendelian random studi overarch goal unravel biolog mechan	D057182;D055106	T062;T063
36,266,698	circadian rhythm plant host influenc rhythmic rhizospher microbiota recent studi demonstr microbiota inhabit plant rhizospher exhibit diel chang abund investig impact plant circadian rhythm bacteri fungal rhythm rhizospher analys tempor chang fungal bacteri communiti rhizospher arabidopsi plant overexpress lack function circadian clock gene late elong hypocotyl lhi	D029681;D017360;D064307	T032;T116;T002;T028;T001
36,266,697	effect inactiv ad ncov covid vaccin sar cov omicron ba variant infect sever ill death limit data avail effect inactiv ad ncov covid vaccin real world use especi omicron variant sar cov infect nave popul	D000086382;D014765	T129;T047;T121;T067
36,266,695	lncrna casc promot cell prolifer invas osteosarcoma target mir psox axi osteosarcoma os common primari malign bone tumor studi aim explor biolog role long code rna lncrna casc regulatori mechan oc	D001859;D035683;D012516;D062085;D055751	T123;T191;T116;T114
36,266,694	integr analysi mc associ gene reveal mettla potenti oncogen breast cancer rna methyl modif especi mrna modif known extens involv tumor develop howev relationship n methylcytidin mc relat gene tumorigenesi rare studi research found mc relat gene express differ level affect patient prognosi across multipl cancer type cancer genom atlas multi omic level import methyltransferas like protein mettla high amplif frequenc patient breast invas carcinoma brca overexpress independ predictor poor overal surviv enrich analysi associ gene reveal mettla may activ dna synthesi cell prolifer pathway brca cell drug sensit analysi trifluridin pd taselisib shown effect drug mettla posit brca patient overal research conduct holist view express level prognost signatur mc relat gene multipl malign import mettla intens explor potenti oncogen brca aid develop potenti drug agent precis therapi breast cancer patient	D001943;D012359	T191;T126;T116
36,266,693	ortner syndrom secondari thorac aortic aneurysm case seri ortner syndrom refer vocal cord paralysi result compress left recurr laryng nerv abnorm mediastin vascular structur retrospect case seri detail experi ortner syndrom due thorac aortic aneurysm	D017545;D014826	T033;T047
36,266,692	comput quantif character independ evolv cellular subpopul within tumor critic inhibit anti cancer therapi resist drug resist continu major limit factor across divers anti cancer therapi contribut complex challeng cancer plastic one cancer subtyp switch anoth respons treatment exampl tripl negat breast cancer tnbc posit breast cancer optim treatment outcom accur tumor diagnosi subsequ therapeut decis vital studi assess novel approach character treatment induc evolutionari chang distinct tumor cell subpopul identifi therapeut exploit anticanc drug resist	D064726;D000970	T121;T191;T109
36,266,691	domino hepatocyt transplant use explant human liver metabol defect attenu galnlp induc acut liver failur explant liver patient inherit metabol liver diseas possess potenti cell sourc good qualiti hepatocyt hepatocyt transplant ht studi evalu therapeut effect domino ht use hepatocyt isol explant human liver acut liver failur alf	D017114;D008659;D022781	T047;T025
36,266,690	function result modifi mason allen sutur versus horizont mattress sutur arthroscop brostrm gould procedur chronic ankl instabl arthroscop brostrm gould procedur abg gain particular attent among clinician research due high rate satisfactori result lack evid regard differ clinic outcom various sutur techniqu purpos studi compar differ clinic effect patient treat one anchor modifi mason allen sutur two anchor horizont mattress sutur chronic ankl instabl cai	D007593;D017844	T033;T023
36,266,689	endoplasm reticulum qualiti control pathway endoplasm reticulum associ degrad mechan regul n glycoprotein n glycan structur diatom phaeodactylum tricornutum tunicamycin inhibit first step protein n glycosyl modif howev physiolog transcriptom n glycom effect tunicamycin import marin diatom phaeodactylum tricornutum still unknown studi comprehens approach use studi effect tunicamycin stress result show cell growth photosynthesi signific inhibit p tricornutum tunicamycin stress solubl protein content signific decreas solubl sugar neutral lipid dramat increas orchestr balanc carbon nitrogen metabol stress g ml tunicamycin result differenti express erqc erad relat gene upregul gene involv erqc pathway activ anti oxidas differenti express gene relat erad mechan might import maintain homeostasi cell identif n glycan especi complex type n glycan structur enrich n glycan databas diatom p tricornutum provid import inform studi function n glycosyl modif protein whole studi propos work model erqc erad provid solid foundat depth studi relat mechan diatom express system	D060746;D017377	T204;T044
36,266,688	develop clinic valid ct base region modifi centiloid method amyloid pet standard centiloid cl method propos harmon quantifi global f label amyloid beta pet ligand use mri anatom refer howev need harmon quantifi region uptak ligand use ct anatom refer present studi develop valid ct base region direct comparison f florbetaben fbb f flutemetamol fmm centiloid rdccl	D000544;D000686	T047;T048
36,266,687	effect visual context visual vestibular mismatch reveal electroderm postur respons measur object criteria exist diagnosi treatment visual vestibular mismatch vvm	D004244;D014722	T184;T023
36,266,684	combin enhanc propionyl coa metabol pathway effici androstenedion product mycolicibacterium neoaurum product androstenedion ad phytosterol mycolicibacterium neoaurum multi step biotransform process requir degrad sterol side chain accompani product propionyl coa howev transient product larg amount propionyl coa accumul intracellular produc toxic effect sever inhibit ad product	D009161;D010840	T121;T123;T007;T109
36,266,683	effect vitamin insulin resist fast blood glucos pregnant women insuffici defici vitamin random placebo control trial gestat diabet one common metabol disord pregnanc studi report effect vitamin defici incid disord therefor purpos present studi determin effect vitamin supplement fast blood glucos fbg level fast blood insulin fbi level insulin resist index homa ir primari outcom symptom depress musculoskelet pain frequenc gestat diabet frequenc abort secondari outcom	D007333;D016640;D059352	T033;T047;T046
36,266,682	hpa mediat heterochromatin format promot antimicrobi respons pseudomona aeruginosa infect pseudomona aeruginosa gram negat bacterium caus sever infecti diseas divers host organ includ human effect therapeut option p aeruginosa infect limit due increas multidrug resist therefor critic understand regul host innat immun respons guid develop effect therapeut option epigenet mechan host regul antimicrobi respons p aeruginosa infect remain unclear use drosophila melanogast investig role heterochromatin protein hpa key epigenet regul mediat heterochromatin format antimicrobi respons pa high virul p aeruginosa strain	D011552	T047
36,266,681	evalu two social norm nudg intervent promot healthier food choic canadian groceri store object studi determin impact two nudg intervent custom produc purchas rural canadian groceri store pre post intervent observ studi design use sale data gather stagger implement two nudg base intervent encourag produc purchas groceri cart divid encourag shopper fill one third cart produc groceri cart plaqu inform mani fruit veget typic purchas store proport total sale account produc compar baselin implement first intervent phase implement first intervent addit second intervent phase baselin post implement intervent togeth relat increas absolut increas produc spend baselin post implement intervent p ci intervent phase specif produc spend show signific chang percentag produc spend baselin phase intervent relat increas absolut increas percentag produc spend phase phase intervent p ci simpl low cost nudg intervent effect increas proport total groceri spend produc studi also demonstr partnership local busi promot healthier food choic rural communiti canada	D000085943;D066262	T078;T073
36,266,680	orsai drosophila homolog human etfrf link lipid catabol growth control lipid homeostasi evolutionarili conserv process crucial energi product storag consumpt drosophila larva feed continu achiev rough fold increas size accumul suffici reserv provid energi nutrient necessari develop adult fli mechan control metabol program poor understood	D004331;D029721;D050356	T123;T044;T116;T204
36,266,679	repeat assess sodium na mri healthi human calf muscl preliminari result tissu sodium concentr subject addison diseas determin relax time sodium nucleus investig repeat quantit vivo tsc measur use sodium magnet reson imag na mri human skelet muscl explor discriminatori valu method compar tscs healthi subject patient addison diseas	D012964;D000224	T123;T196;T034;T047
36,266,678	mortal diseas circulatori system brazil relationship social determin focus vulner ecolog studi death diseas circulatori system ischem heart diseas declin slowli develop countri emphas probabl relationship determin social vulner	D017202;D002319	T022;T047
36,266,676	preval thyroid dysfunct jordan nation popul base survey object studi assess preval clinic subclin hypo hyperthyroid associ factor among jordanian adult	D006980;D007037;D013959	T047
36,266,675	use genet encod fluoresc biosensor interrog ovarian cancer metabol epitheli ovarian cancer oc lethal gynecolog malign patient present signific metastat burden particular adipos rich microenviron omentum recent evid highlight import metabol adapt enabl metastasi lead signific interest evolv arsenal tool use studi oc metabol studi demonstr capabl genet encod fluoresc biosensor studi oc focus organoid model better recapitul vivo tumor microenviron	D010051;D015374	T191;T059;T075
36,266,674	explain machin learn method respiratori oscillometri diagnosi respiratori abnorm sarcoidosi work develop mani machin learn classifi assist diagnos respiratori chang associ sarcoidosi base result forc oscil techniqu fot non invas method use assess pulmonari mechan addit accur result particular interest interpret explain use genet program sinc classif made intellig express also evalu featur import differ experi find discrimin featur	D000069550;D012507	T047;T066
36,266,673	genet modifi organ adapt regulatori framework evolv genom edit technolog genet modif live organ prosper activ research develop agricultur industri biomed applic three decad pass sinc first genet modifi product obtain transgenesi becom avail market regulatori framework across world abl keep date new technolog monitor safeti concern new genom edit techniqu open new avenu genet modif develop use put pressur framework discuss implic definit livinggenet modifi organ evolv genom edit tool obtain regulatori framework around world taken technolog account focus agricultur crop final expand review beyond commerci crop address live modifi organ use food industri biomed applic climat chang orient solut	D000072669;D018556	T063;T002
36,266,668	effect differ feed method gastrointestin function critic patient dfm gfc studi protocol random control trial enter nutrit major pathway nutrit patient requir critic care howev remain unclear whether intermitt continu feed better approach especi nasogastr enter nutrit via gastric tube therefor random control clinic studi design observ effect differ method critic ill patient	D016638;D011788	T078;T047
36,266,667	simultan femor head reduct osteotomi fhro combin periacetabular osteotomi pao treatment sever femor head aspher perth diseas purpos studi describ midterm clinic radiolog outcom concurr femor head reduct osteotomi fhro periacetabular osteotomi pao legg calv perth diseas lcpd patient major aspher femor head deform	D007873;D006618	T019;T047
36,266,666	associ co occur mental health problem hepat c status among young peopl inject drug rural new mexico inject drug use idu remain strongest risk factor hepat c virus hcv unit state hcv rate increas rural area among young adult peopl inject drug pwid peopl hcv pwid disproportion rate mental health problem howev unclear whether riski inject behavior mediat associ mental health problem hcv examin associ mental health problem hcv rural cohort young adult pwid goal inform rural servic deliveri	D015819;D055030;D015658;D006526	T098;T033;T047;T101;T048
36,266,665	combin associ triglycerid glucos index systol blood pressur caus cardiovascular mortal among general popul combin associ triglycerid glucos tyg index differ systol blood pressur sbp level caus cardiovascular mortal among general popul remain unclear	D005947;D002318	T123;T047;T121;T109
36,266,663	replic stress generat distinct landscap dna copi number alter chromosom scale loss major driver cancer chromosom instabl replic stress slow stall dna replic replic stress genom instabl connect known aphidicolin induc replic stress induc breakag common fragil site exact caus fragil debat acut genom consequ replic stress fulli explor	D056915;D009369	T045;T191;T086
36,266,662	identif window androgen sensit somat cell function human fetal testi cultur ex vivo reduc androgen action earli fetal develop suggest origin reproduct disord compris within testicular dysgenesi syndrom tds hypothesi support studi rat demonstr normal male develop adult reproduct function depend suffici androgen exposur sensit fetal period call masculin program window mpw main aim studi therefor examin effect manipul androgen product differ timepoint earli human fetal testi develop identifi exist time possibl window androgen sensit resembl mpw rat	D013735;D013737	T125;T023
36,266,661	male partner involv human immun defici virus test counsel prenat care visit bichena town westcentr ethiopia cross section studi transmiss human immun defici virus hiv mother child remain signific problem develop countri male partner involv hiv test counsel major entri point prevent mother child transmiss pmtct hiv studi aim assess male partner involv hiv test counsel prenat care visit bichena town westcentr ethiopia	D015658;D011251	T047
36,266,660	matern blood pressur associ placent dna methyl direct alter cell type composit matern blood pressur level reflect cardiovascular adapt pregnanc proper matern fetal exchang placenta sensit numer environment stressor matern hypertens pregnanc associ impair placent function increas risk children suffer cardiovascular respiratori diseas later investig chang placent dna methyl level cell type composit associ matern blood pressur could help elucid relationship placent fetal develop	D019175;D006973	T047;T044
36,266,658	target deliveri ros respons releas resolvin platelet chimer liposom amelior myocardi ischemia reperfus injuri resolvin rvd shown provid effect protect ischemia reperfus injuri multipl vital organ heart brain kidney howev clinic translat potenti system administr rvd treatment ischemia reperfus injuri great limit due biolog instabl lack target abil combin natur inflammatori respons reactiv oxygen speci ros overproduct reperfus injuri develop platelet bionic ros respons rvd deliveri platform result formul enabl target deliveri rvd injuri site hijack circul chemotact monocyt achiev local control releas mous model myocardi ischemia repefusuin mir injuri intraven inject formula result enrich rvd injur area turn promot clearanc dead cell product special proresolv mediat spms angiogenesi injuri repair effect improv cardiac function deliveri system integr drug bio protect target deliveri control releas endow great clinic translat valu	D008081;D015428	T046;T109
36,266,656	scale amoeba base process product cannabinoid precursor olivetol acid avail new biolog platform organ get access innov product process fundament progress biotechnolog bioeconomi amoeba dictyostelium discoideum repres novel host system recent employ discoveri new natur product cell factori product bioactiv compound phytochem howev essenti paramet evalu potenti new host system demonstr scalabl allow industri applic aim develop bioprocess product olivetol acid main precursor cannabinoid synthes recent engin discoideum strain	D000656;D004023;D002186;D061065;D001688	T121;T123;T204;T109
36,266,655	valu combin simpl anthropometr obes paramet bodi mass index bmi bodi shape index absi assess risk non alcohol fatti liver diseas bodi mass index bmi bodi shape index absi current independ risk factor non alcohol fatti liver diseas nafld aim studi explor valu combin two common obes index identifi nafld	D065626;D009767	T047
36,266,654	antivir activ mechan antifung drug anidulafungin suggest potenti promot treatment viral diseas sever fever thrombocytopenia syndrom diseas sfts caus novel tick born sfts virus sftsv list among top prioriti infecti diseas world health organ due high fatal rate lack effect antivir drug vaccin therefor rais urgent need develop effect anti sftsv drug improv diseas treatment	D000077612;D002044;D014777	T121;T047;T116
36,266,653	nadph sensor regul cell ferroptosi ferroptosi new form program cell death achiev great breakthrough cell biolog past decad howev regul ferroptosi yet identifi thorough latest studi publish natur cell biolog nguyen colleagu found new nadph sensor marchf e ubiquitin ligas mediat ferroptosi tumor growth anim develop find provid novel insight ubiquitin system energi metabol regul ferroptosi may open new avenu tumor treatment	D000079403	T043
36,266,652	influenc hyaluron acid intra articular friction biomechan studi whole anim joint cartilag mechan high stress tissu human bodi import part synovi joint joint cartilag lubric synovi fluid hyaluron acid ha main compon howev joint osteoarthr ha lower concentr molecular weight compar healthi joint recent year intra articular inject therapeut ha lubric becom popular therapi effect ha applic friction complet joint physiolog movement need determin	D002358;D006820	T123;T121;T024;T109;T122
36,266,651	global burden trend rotavirus infect associ death observ trend studi rotavirus lead global pathogen diarrhea associ mortal pose great threat public health age group studi aim explor global burden year chang pattern rotavirus infect associ death	D012400	T047
36,266,650	identifi stroke diagnosi relat featur medic imag report improv clinic decis make support medic imag report play import role communic diagnost inform radiologist clinician head magnet reson imag mri report provid evid wide use diagnosi treatment ischaem stroke high signal region diffus weight imag dwi imag mri report key evid correct identifi high signal region dwi imag help treatment ischaem stroke patient sinc multipl signal record head mri report appear part challeng identifi high signal region dwi imag mri report	D020521;D002545;D000083242	T047;T046
36,266,648	reduct posterior disloc hip prosthesi use modifi later posit maneuv retrospect clinic compar follow studi posterior disloc pd common complic total hip arthroplasti tha alli maneuv wide use method reduct howev classic maneuv disadvantag aim present studi investig whether modifi later posit mlp reduct maneuv provid easier safer method pd reduct alli maneuv	D006622;D006617;D019644	T061;T074;T190;T037
36,266,647	knowledg silesia adult inhabit regard prevent vaccin effect cardiovascular diseas protect vaccin import maintain health reduc suffer infecti diseas also vaccin prevent infecti diseas associ develop progress cardiovascular diseas	D002318;D003141;D014612	T129;T047;T121;T116
36,266,646	knowledg attitud percept medic student toward mental health univers uganda preval mental ill among medic student high gap remain knowledg given improv attitud percept toward mental health despit vast bodi literatur global studi conduct uganda assess level knowledg attitud percept among medic student uganda	D013337;D001523	T097;T048
36,266,645	compar genom transcriptom analys tran kingdom pathogen fusarium solani speci complex reveal degre compartment fusarium solani speci complex fssc compris fungal pathogen respons mortal divers rang anim plant genom divers transcriptom respons anim pathogen remain elucid sequenc assembl annot six chromosom level fssc clade genom aquat anim plant host origin establish pathosystem investig express data f falciform f keratoplasticum chines softshel turtl pelodiscus sinensi host	D005670	T004
36,266,644	overwork among resid physician nation questionnair survey result resid experi longest work hour among physician thus would benefici perform nationwid survey japan resid long work hour background factor promot upper limit work hour japanes resid aim studi studi assess state physician excess work hour background factor use questionnair survey	D007396;D010820	T065;T097
36,266,643	trend inequ matern child health health care uganda analysi uganda demograph health survey uganda made great stride improv matern child health howev littl known improv distribut across differ socioeconom categori health inequ chang time studi analys data demograph health survey dhs conduct uganda assess trend inequ varieti mother child health health care indic	D007306;D008427	T131;T058
36,266,642	comparison visual outcom diffract trifoc intraocular len refract bifoc intraocular len eye axial myopia prospect cohort studi assess compar efficaci safeti accuraci predict visual qualiti diffract trifoc intraocular len iol refract rotate asymmetr bifoc iol eye axial myopia	D007910;D009216;D018918	T061;T047;T074
36,266,641	perform biofir blood cultur identif panel bcid detect bloodstream pathogen associ resist marker systemat review meta analysi diagnost test accuraci studi earli identif bloodstream pathogen associ antimicrobi resist may shorten time optim therapi patient sepsi biofir blood cultur identif panel bcid novel multiplex pcr detect target direct posit blood cultur reduc turnaround time	D016470;D055624	T047;T007
36,266,640	comprehens analysi lncrna mediat cerna regulatori network key gene associ papillari thyroid cancer coexist hashimoto thyroid incid papillari thyroid cancer ptc concomit hashimoto thyroid ht gradual increas past decad studi aim identifi differenti express lncrnas tumor tissu ptc without ht confer better understand lncrna base compet endogen rna cerna network ptc ht	D062085;D050031;D035683;D013964	T123;T047;T191;T114
36,266,639	efficaci diet fatigu qualiti life disabl status multipl sclerosi patient rapid review meta analysi random control trial multipl sclerosi inflammatori neurodegen diseas peopl multipl sclerosi pwms experi chronic fatigu difficult deal therapeut great affect health relat qualiti life qol pwms awar lack general dietari advic relat diseas lead self experiment diet necessari provid object inform dietari intervent pwms aim provid object synthesi evid efficaci safeti specif diet pwms rapid review meta analys random control trial rcts examin symptomat fatigu mfis qol expand disabl status scale edss sever advers event	D011788;D009103	T078;T047
36,266,638	axillari vein thrombosi h caesarean section case report literatur review axillari vein thrombosi rare disord howev case axillari vein thrombosi short caesarean section report previous report case axillari vein thrombosi h caesarean section due unidentifi aetiolog	D056824	T047;T046
36,266,637	genom associ extend spectrum lactamas produc esbl ampc produc e coli small medium pig farm khon kaen provinc thailand thailand undergo rapid intensif livestock product small subsist farm medium size commerci farm coexist medium farm antimicrobi prescrib veterinarian wherea small farm antimicrobi use remain larg unsupervis impact differ well farm practic emerg composit antimicrobi resist gene arg remain larg unknown analyz genom extend spectrum lactamas produc esbl andor ampc produc escherichia coli recov human pig small medium farm khon kaen provinc thailand test genom wide associ identifi link arg host farm size pig isol small farm associ mcr qnr gene confer resist colistin fluoroquinolon respect contrast pig isol medium farm associ arg confer resist drug common use medium farm ie streptomycin esbl plasmid small farm co carri arg confer resist critic import antimicrobi frequent compar plasmid medium farm frequent arg combin includ bla ctx qnrs vs small medium farm respect bla ctx qnrs mcr vs bla ctx qnrs vs bla ctx qnrs mcr vs co locat plasmid arg confer resist critic import antimicrobi defin world health organ concern action curb spread urgent need legisl limit antimicrobi sale initi better inform farmer veterinarian appropri antimicrobi usag farm biosecur could help reduc antimicrobi use farm	D004927;D000890;D029968	T121;T047;T116
36,266,636	cardiac cephalalgia narrat review ichd criteria evalu cardiac cephalalgia unusu condit occur episod myocardi ischemia inform cardiac cephalalgia scarc characterist physiopatholog remain unclear aim provid narrat review clinic characterist physiopatholog cardiac cephalalgia evalu current diagnost criteria method search pubm undertaken studi cardiac cephalalgia publish th septemb summar literatur provid comprehens review headach characterist possibl mechan also evalu current intern classif headach disord third edit diagnost criteria base prior report case result total case found headach characterist variabl occipit locat throb pain frequent report headach accompani case cardiac symptom criterion b fulfil case criterion c criteria ca cb respect regard headach featur describ diagnost criterion c moder sever intens accompani nausea accompani photophobia phonophobia aggrav exert report case respect	D020773;D017202	T047
36,266,635	construct analysi sampl specif driver modul breast cancer import understand function impact somat mutat methyl aberr individu level implement precis medicin recent studi demonstr perturb gene interact network provid fundament link genotyp epigenotyp phenotyp howev unclear individu mutat affect function biolog network especi individu methyl aberr solv provid sampl specif driver modul construct method use order network theori hub gene theori identifi individu perturb network driven mutat methyl aberr	D053263;D009369	T191;T044
36,266,634	evalu diagnost perform h base block elisa specif detect pest des petit rumin domest sheep goat cattl camel pest des petit rumin virus pprv caus high devast diseas sheep goat pest des petit rumin ppr target global control erad serolog diagnost tool kit accur diagnosi ppr inher strength weak requir parallel valid optim across anim speci thus object studi evalu diagnost perform haemagglutinin base ppr block elisa hppr b elisa develop africa union pan african veterinari vaccin center specif detect anti pprv antibodi	D029021;D015511;D012757;D018107	T047;T005
36,266,633	aav ie mediat ucp overexpress acceler inner hair cell loss age vivo uncoupl protein ucp activ excess reactiv oxygen speci ros vivo dual effect reduc ros protect oxid stress reduc atp product regul cellular metabol ucp ros increas cochlea age relat hear loss arhl howev role ucp sensori hair cell arhl remain unclear	D006199;D034381	T033;T047;T025
36,266,632	health equiti characterist research explor unmet communiti mobil need older adult scope review unmet communiti mobil need older adult publish sinc announc un sustain develop goal synthesis describ health equiti characterist research identifi unmet communiti mobil need older adult	D000069576;D006233	T101;T080
36,266,631	quantit dce mri predict breast cancer recurr follow neoadjuv chemotherapi preliminari studi breast cancer patient treat neoadjuv chemotherapi nact risk recurr depend clinicopatholog characterist preliminari studi aim investig predict perform quantit dynam contrast enhanc dce mri paramet alon combin clinicopatholog variabl predict recurr patient treat nact	D020360;D001943	T061;T191
36,266,630	explor carer resili context dementia meta synthesi aim literatur review integr result qualit research resili experi famili carer peopl dementia pwd	D017028;D003704	T099;T098;T097;T048
36,266,628	reliabl evid guid decis make foot ulcer prevent diabet overview systemat review reliabl evid effect intervent prevent diabet relat foot ulcer essenti inform clinic practic well conduct systemat review synthesis evid relev trial offer robust evid decis make conduct overview assess comprehens util avail secondari evid reliabl sourc robust estim effect aim inform cost effect care pathway use econom model report detail overview prospero databas crd	D003920;D017719	T047
36,266,627	lymphocyt c reactiv protein ratio could better predict prognosi patient stage iv cancer system inflamm current regard hallmark cancer studi aim accur clarifi prognost valu various inflammatori marker patient stage iv cancer	D002097;D008175	T129;T191;T116
36,266,626	multi object data enhanc deep learn base ultrasound analysi recent deep learn base automat generat treatment recommend attract much attent howev medic dataset usual small may lead fit inferior perform deep learn model paper propos multi object data enhanc method indirect scale medic data avoid fit generat high quantiti treatment recommend specif defin main sever auxiliari task dataset train specif model task learn differ aspect knowledg limit data scale meanwhil soft paramet share method exploit share learn knowledg among model share knowledg learn auxiliari task main task propos method take differ semant distribut account train process main task collect ultrasound dataset thyroid nodul contain find impress treatment recommend label profession doctor conduct various experi dataset valid propos method justifi better perform exist method	D016571;D000077321	T170;T066
36,266,625	differenti distribut steroid hormon signal network human choroid retin pigment epitheli complex retin pigment epithelium rpe layer pigment cell lie neurosensori retina under choroid play critic role maintain function integr photoreceptor cell mediat communic neurosensori retina choroid prior studi demonstr neurotroph effect select steroid mitig develop progress retin degen diseas via array distinct mechan action	D019636;D012162	T047;T046
36,266,624	disentangl chang across time true stabil employe resili use latent state model debat within literatur whether resili consid stabl charact trait dynam changeabl process state two wide use measur assess resili connor davidson resili scale cd risc resili scale adult rsa aim studi evalu true stabil invari chang across time resili captur two measur use perspect latent state trait theori aim deciph cd risc rsa trait like state like address whether true differ resili particip increas decreas across time longitudin studi uk base employe n complet cd risc item version rsa item version aggreg analyz six parcel three occas six month latent state model latent state model indic specif residu factor util analysi suggest questionnair captur trait state compon resili result contribut discuss resili scale measur chang stabil defin resili trait like state like phenomena find also highlight issu resili scale measur whether resili quantifi construct	D055500	T055
36,266,623	helena low predict factor respons neoadjuv chemotherapi earli breast cancer express prognost predict impact earli stage breast cancer bc posit bc immunohistochemistri ihc score situ hybrid ish amplif treat target therapi concept low bc ihc score without ish amplif draw attent anti treatment recent shown efficaci subgroup aim explor respons neoadjuv chemotherapi nac low earli bc accord score without amplif	D020360;D001943	T061;T191
36,266,622	earli feed practic bodi mass index z score among saudi preschool cross section studi feed practic earli year may long last influenc eat behavior growth pattern bodi mass index bmi trajectori object studi character earli feed practic among mother saudi arabia examin associ child birthweight bmi z score bmiz preschool	D005247;D001942	T055;T058;T040
36,266,621	unmet need iron defici periton dialysi delphi consensus panel anaemia iron defici id common chronic kidney diseas ckd patient relat outcom grow interest role iron supplement ckd particular ferric carboxymaltos fcm also relat use erythropoiesi stimul agent esa despit greater knowledg id manag patient receiv haemodialysi pauciti data exist periton dialysi pd furthermor aim paper provid result nationwid italian survey id pd use delphi method	D006397;D000090463;D051436;D010530;D018798	T061;T121;T047
36,266,620	predictor nurs home admiss older popul belgium longitudin follow health interview survey particip studi examin predictor nurs home admiss nha belgium order contribut better plan futur demand nurs home nh servic health care resourc	D000544;D014549	T047;T046;T048
36,266,619	lesson learn implic earli therapi coronavirus diseas territori servic centr calabria region retrospect studi monoclon antibodi mab antivir approv earli therapi coronavirus diseas covid howev real life set difficulti prescrib therapi within day symptom onset recommend effect combin use drug hypothesis risk patient immunocompromis data support strategi limit	D000086402;D000086382	T005;T067;T047
36,266,618	innov approach base real world big data mine calcul sampl size refer interv establish use transform parametr non parametr method current direct method main approach establish refer interv ri howev hand studi describ effect sampl size establish ri estim sampl size describ novel approach estim sampl size establish ris use transform parametr non parametr method	D013974;D014284	T125;T121;T116;T109
36,266,617	detect ct radiculopathi measur root motor conduct time root motor conduct time rmct noninvas evalu status proxim root segment howev clinic applic remain limit wider studi regard use scarc aim investig associ ct level radiculopathi rmct	D011843	T047;T037
36,266,616	molecular characterist global lactamas produc enterobact cloaca genom analysi analyz characterist global lactamas produc enterobact cloaca includ distribut lactamas sequenc type sts well plasmid replicon	D016972;D001618	T007;T126;T116
36,266,615	effect comput aid row exercis system improv muscl strength function older adult mild knee osteoarthr random control clinic trial osteoarthr oa common age adult result muscl weak function limit lower limb knee oa affect qualiti life elder technolog support feedback achiev lower impact knee joint individu exercis could benefit elder patient knee oa herein comput aid feedback row exercis system propos effect improv muscl strength health condit knee function older adult mild knee oa investig	D020370;D000073678	T047;T056
36,266,614	surgic efficaci surviv predict patient unspecifi malign bone tumor surgic efficaci prognost outcom patient unspecif malign bone tumor umbt remain unclear studi address clinicopatholog featur prognost determin patient umbt nomogram develop clinician predict short long term outcom individu umbt surgeri improv outcom umbt patient receiv radiotherapi chemotherapi balanc confound bias	D049451;D001859	T081;T170;T191
36,266,613	effect topic timolol prevent radiat induc dermat breast cancer pilot tripl blind placebo control trial radiat therapi one standard method treatment breast cancer radiotherapi induc dermat rid common complic radiotherapi rt result less toler rt even discontinu treatment timolol adrenerg receptor antagonist present best wound heal effect chronic incur wound heal topic form timolol could effect prevent rid due role adrenerg receptor skin cell keratinocyt migrat well anti inflammatori effect timolol howev placebo control random trial avail confirm role current trial aim evalu efficaci topic timolol ww rid sever patient qualiti life qol	D001943;D011855;D013999	T121;T109;T191;T037;T047

36,266,763

brain target near infrar nanobeacon situ monitor h fluctuat epilept seizur epilepsi neurolog brain diseas recurr seizur relat reduct substanc power antioxid defens system ad howev report studi situ antioxid fluctuat epilepsi vari sever work hydrogen sulfid h select model target h respons near infrar fluorophor design synthes amphiphil molecul synthes modifi angiopep peptid hydrophil terminus nanobeacon term bfpp prepar format micell packag fluorophor nanobeacon sensit h low detect limit nm h fluctuat cell monitor fluoresc imag addit angiopep peptid surfac bfpp help cross blood brain barrier near infrar fluoresc improv vivo imag bfpp reveal h moder level normal brain level obvious elev mild epilepsi activ ad signific suppress sever epilepsi due neuron damag approach general access target alter respons fluorophor signific situ analysi brain patholog

D006862;D004827

T131;T197;T033;T047;T130

36,266,731

circlrfn inhibit progress glioblastoma via prrxgch mediat ferroptosi ferroptosi novel form iron depend cell death particip malign progress glioblastoma gbm although circular rnas circrna found play key role ferroptosi via sever mechan includ regul iron metabol glutathion metabol lipid peroxid mitochondri relat protein mani novel circrna regul ferroptosi need found may becom new molecular treatment target gbm

D001932;D000079403;D005909;D005910;D000079962

T191;T114;T043

36,266,729

spontan ruptur larg splenic arteri aneurysm year old male patient pemphigus vulgari case report current inform anatom risk factor splenic arteri aneurysm ruptur specif locat size lesion therefor report entiti obtain data ultim reduc morbid mortal essenti report case male patient spontan ruptur larg splenic arteri aneurysm present abdomin pain

D010392;D017542;D013161;D005767

T047;T037

36,266,728

pdcd inhibit progress renal cell carcinoma promot cell immun involv hdacmicrorna psgk epigenet exert vital role onset develop renal cell carcinoma rcc mount evid shed light signific human immun system respons tumor infiltr cell herebi sought unmask immunomodulatori role histon deacetylas hdac potenti upstream molecul program cell death pdcd rcc

D051017;D002292;D007680;D035683;D009363

T123;T191;T116;T114

36,266,727

lung resect surgeri jehovah wit patient year singl center experi pauciti literatur surgic outcom jehovah wit jw patient undergo lung resect suggest patient oper lung cancer may deni resect aim studi better understand periop outcom long term cancer surviv jw patient undergo lung resect

D002289;D008175;D033221

T098;T191

36,266,726

casa comprehens databas resourc covid altern splice atlas key process transcript regulatori mechan altern splice play crucial role maintain divers rna protein express mediat immun respons infecti diseas especi covid therefor urgent data gather research profil microb infect human cell need improv understand covid relat infecti diseas herein creat casa covid altern splice atlas provid conveni comput platform studi covid covid relat infecti diseas

D017398;D000086382

T123;T067;T045;T114;T047

36,266,725

novel pathogen variant cubn uncoupl proteinuria renal function proteinuria unfavor clinic condit high associ risk renal cardiovascular diseas chronic kidney diseas ckd howev whether proteinuria form link renal impair still unclear cubilin endocyt receptor high express renal proxim tubul mediat uptak albumin transferrin microglobulin

D007668;D011507

T033;T023

36,266,721

hpv e alter transles synthesi signal subset human papillomavirus hpvs caus virtual everi cervic cancer call high risk hpvs encod two major oncogen hpv e e necessari transform among high risk hpvs hpv caus cervic cancer often use repres model oncogen hpvs hpv e oncogen facilit hpv lifecycl bind destabil rb ensur virus access cellular replic machineri rb destabil increas ef respons gene express caus replic stress hpv e mitig deleteri effect associ replic stress degrad p cell undergo separ adapt toler stress demonstr includ activ transles synthesi tls pathway prevent replic stress caus replic fork collaps show signific elev tls gene express common cervic cancer cancer type analyz addit increas tls protein abund hpv e express cell reduc abil induct critic tls factor pol respons replic stress induc agent final show increas express least one tls gene associ improv surviv women cervic cancer

D002583;D050725

T123;T191;T116

36,266,719

prognosi relat nutrit score cancer patient prns clinic nutrit score deriv retrospect cohort studi nutrit assess qualiti life qol becom import indic therapeut efficaci patient malign aim develop valid easi use questionnair prognost valu assess nutrit status hospit cancer patient

D009369;D011788

T078;T191

36,266,718

effect capit polici withdraw matern health servic provis ashanti region ghana interrupt time seri analysi payment method known influenc matern care deliveri health system ghana suspend pilot capit provid payment system near five year implement studi aim examin effect ghana capit polici matern health care provis part lesson learn bridg critic literatur gap

D008427

T058

36,266,717

reprogram sentinel lymph node microenviron tumor metastasi metastasi major caus death patient cancer two main rout cancer cell dissemin blood lymphat system under mechan hematogen metastasi well character past decad howev understand molecular basi lymphat metastasi remain prematur stage conceptu cancer cell invad lymphat capillari passiv move collect lymphat vessel migrat sentinel lymph node sln first lymph node cancer cell spread primari tumor enter blood circulatori system via subclavian vein arriv cancer cell releas specif solubl factor modul microenviron sln establish beachhead success colon colon cancer cell inhibit anti tumor immun induc recruit regulatori cell myeloid deriv suppressor cell suppress function dendrit cell cd cell promot releas immunosuppress cytokin develop novel strategi revers cancer cell trigger sln remodel may activ immun reduc beachhead buildup distant metastasi addit microanatom locat metastasi sln also import site immun modul nanotechnolog base approach deliv lymph node tropic antibodi drug conjug nanoparticl kill cancer cell site new direct cancer treatment convers induct stronger immun promot antigen present lymph node provid altern way enhanc efficaci immun checkpoint therapi cancer vaccin review articl summar recent find reprogram sln lymphat invas discuss possibl inhibit tumor metastasi elicit anti tumor immun target sln

D000071036;D019496;D001943

T129;T121;T116;T191;T023

36,266,716

whether individu dose escal recommend lymph node differ size definit radiotherapi cervic cancer dose escal posit node mayb improv region control patient node posit cervic cancer optim dose node differ size remain controversi purpos studi explor individu dose escal lymph node lns differ size definit radiotherapi cervic cancer

D002583

T191

36,266,715

influenc year nuss bar placement bar remov case report nuss bar common use minim invas correct pectus excavatum usual remov within year report case year bar placement nuss procedur accompani uniqu complic thorac malform describ asymmetr pectus carinatum caus bar displac signific rib periost hyperplasia describ first time

D005660

T019

36,266,714

factor associ mother health care seek behaviour childhood fever burkina faso find repeat cross section household survey fever one frequent reason paediatr consult burkina faso health care seek behaviour factor associ health care seek event childhood fever poor document studi aim analys health care seek behaviour factor associ health care seek childhood fever burkina faso

D009035;D010342

T080;T092;T099;T055;T058

36,266,713

endoscop combin intraren surgeri prone split leg posit versus galdakao modifi supin valdivia posit manag partial staghorn calculi evalu compar outcom ecir treatment partial staghorn renal calculi prone split leg posit versus gmsv posit regard technic aspect success rate oper time complic safeti effect approach

D000069856;D009403;D007669

T061;T047

36,266,712

determin affect utilis health servic treatment children rural nepali health centr cross section studi larg inequ child health remain nepal cast ethnic sex major determin depriv negat outcom purpos studi explor whether key demograph associ health seek behaviour utilis health care treatment receiv

D010342;D011014

T050;T080;T055;T047;T058

36,266,711

innov approach monitor perform integr diseas surveil respons ebola outbreak sierra leon lesson field supervis healthcar worker improv perform done support object manner regular supervis support function integr diseas surveil respons idsr strategi allow systemat monitor idsr implement start develop partner support ministri health sanit moh revit idsr sierra leon monitor progress support supervis assess report find assess

D019142

T047

36,266,710

develop novel dna marker speci discrimin fasciola fluke base fatti acid bind protein type gene multiplex polymeras chain reaction pcr pcr restrict fragment length polymorph rflp nuclear phosphoenolpyruv carboxykinas pepck polymeras delta pold respect use differenti fasciola hepatica f gigantica hybrid fasciola fluke howev discrimin error report method studi aim develop multiplex pcr base novel nuclear marker fatti acid bind protein type fabp type gene

D005209;D005211

T047;T204

36,266,709

preval factor associ postpartum pelvic girdl pain among women poland prospect observ studi pelvic girdl pain pgp type pregnanc relat lumbopelv pain studi aim examin preval sever factor associ postpartum pgp select group postpartum women poland

D059388;D011248

T033;T047;T046

36,266,708

intervent address potenti inappropri prescript counter medic use among adult year older primari care set protocol systemat review inform recommend canadian task forc prevent health care potenti inappropri prescrib counter otc medic use among adult age year older primari care set protocol outlin plan scope method systemat review benefit harm accept intervent reduc potenti inappropri prescript otc medic use

D057970;D011788

T078;T058

36,266,707

homemad pin hook surgic treatment posterior cruciat ligament avuls fractur treat posterior cruciat ligament pcl tibial insert small comminut avuls fractur still challeng studi evalu clinic radiolog outcom orif pcl tibial insert avuls fractur invert l shape postero medial approach use homemad pin hook

D016119;D000071562;D013978;D018460

T023;T037

36,266,705

blacksmith approach strategi teach learn medic anatomi cours qualit studi anatomi symbol essenti core topic one fundament pillar medic paramed knowledg nevertheless exploratori data analys focus student approach learn anatomi studi examin student perceiv learn experi anatomi lesson make model promot meaning learn profession ident

D013337;D004504;D000715

T065;T091;T097

36,266,704

role model covid pandem mathemat statist model play import role analysi data covid import track progress pandem understand spread popul perhap signific forecast futur cours pandem evalu potenti polici option articl describ type model use research team israel present assumpt basic element illustr use influenc decis articl grew modelist dialog organ israel nation institut health polici research particip leader local model effort

D000086382

T047;T067

36,266,703

five year experi valu base qualiti improv team key factor success implement hospit care recent year valu base healthcar vbhc becom one accept concept fix broken healthcar system numer hospit embrac vbhc tri implement valu base qualiti improv vbqi practic howev lack knowledg practic implement vbhc organ differ approach aim studi explor main factor experienc hinder andor support implement vbqi team hospit care

D058996;D003695

T058;T093;T057

36,266,701

systemat review distribut take home naloxon low middl incom countri barrier implement take home naloxon program opioid overdos epidem hit record high worldwid account mortal relat substanc use take home naloxon thn strategi implement mani develop countri suffer high opioid overdos death rate aim provid overdos identif naloxon administr train along thn deliveri opioid user other like wit overdos incid famili member peer howev littl known measur low middl incom countri lmic opioid use opioid relat death report high systemat literatur review aim examin distribut thn lmic review studi identifi barrier implement thn program worldwid assess applic lmic

D000083682;D062787;D009293

T037;T048

36,266,700

understand perspect recruit key improv randomis control trial enrol qualit evid synthesi recruit patient randomis control trial rcts often report challeng evid base effect intervent could use staff recruit undertak recruit lack although experi perspect recruit wide report evid synthesi requir order inform develop futur intervent paper aim address systemat search synthesis evid recruit perspect experi recruit patient rcts method qualit evid synthesi qes follow thoma harden approach themat synthesi conduct ovid medlin cinahl embas psycinfo cochran central regist control trial orrca web scienc electron databas search studi sampl ensur focus research align phenomena interest qes methodolog relev qes question includ variat across clinic area studi grade cerqual framework use assess confid review find

D006282;D001291

T041;T097

36,266,699

causal genet determin metabolit anxieti disord two sampl mendelian random studi although anxieti disord one preval mental disord under biolog mechan yet fulli elucid recent year genet determin metabolit gdms use reveal biolog mechan mental disord howev strategi appli anxieti disord herein explor causal gdms anxieti disord mendelian random studi overarch goal unravel biolog mechan

D057182;D055106

T062;T063

36,266,698

circadian rhythm plant host influenc rhythmic rhizospher microbiota recent studi demonstr microbiota inhabit plant rhizospher exhibit diel chang abund investig impact plant circadian rhythm bacteri fungal rhythm rhizospher analys tempor chang fungal bacteri communiti rhizospher arabidopsi plant overexpress lack function circadian clock gene late elong hypocotyl lhi

D029681;D017360;D064307

T032;T116;T002;T028;T001

36,266,697

effect inactiv ad ncov covid vaccin sar cov omicron ba variant infect sever ill death limit data avail effect inactiv ad ncov covid vaccin real world use especi omicron variant sar cov infect nave popul

D000086382;D014765

T129;T047;T121;T067

36,266,695

lncrna casc promot cell prolifer invas osteosarcoma target mir psox axi osteosarcoma os common primari malign bone tumor studi aim explor biolog role long code rna lncrna casc regulatori mechan oc

D001859;D035683;D012516;D062085;D055751

T123;T191;T116;T114

36,266,694

integr analysi mc associ gene reveal mettla potenti oncogen breast cancer rna methyl modif especi mrna modif known extens involv tumor develop howev relationship n methylcytidin mc relat gene tumorigenesi rare studi research found mc relat gene express differ level affect patient prognosi across multipl cancer type cancer genom atlas multi omic level import methyltransferas like protein mettla high amplif frequenc patient breast invas carcinoma brca overexpress independ predictor poor overal surviv enrich analysi associ gene reveal mettla may activ dna synthesi cell prolifer pathway brca cell drug sensit analysi trifluridin pd taselisib shown effect drug mettla posit brca patient overal research conduct holist view express level prognost signatur mc relat gene multipl malign import mettla intens explor potenti oncogen brca aid develop potenti drug agent precis therapi breast cancer patient

D001943;D012359

T191;T126;T116

36,266,693

ortner syndrom secondari thorac aortic aneurysm case seri ortner syndrom refer vocal cord paralysi result compress left recurr laryng nerv abnorm mediastin vascular structur retrospect case seri detail experi ortner syndrom due thorac aortic aneurysm

D017545;D014826

T033;T047

36,266,692

comput quantif character independ evolv cellular subpopul within tumor critic inhibit anti cancer therapi resist drug resist continu major limit factor across divers anti cancer therapi contribut complex challeng cancer plastic one cancer subtyp switch anoth respons treatment exampl tripl negat breast cancer tnbc posit breast cancer optim treatment outcom accur tumor diagnosi subsequ therapeut decis vital studi assess novel approach character treatment induc evolutionari chang distinct tumor cell subpopul identifi therapeut exploit anticanc drug resist

D064726;D000970

T121;T191;T109

36,266,691

domino hepatocyt transplant use explant human liver metabol defect attenu galnlp induc acut liver failur explant liver patient inherit metabol liver diseas possess potenti cell sourc good qualiti hepatocyt hepatocyt transplant ht studi evalu therapeut effect domino ht use hepatocyt isol explant human liver acut liver failur alf

D017114;D008659;D022781

T047;T025

36,266,690

function result modifi mason allen sutur versus horizont mattress sutur arthroscop brostrm gould procedur chronic ankl instabl arthroscop brostrm gould procedur abg gain particular attent among clinician research due high rate satisfactori result lack evid regard differ clinic outcom various sutur techniqu purpos studi compar differ clinic effect patient treat one anchor modifi mason allen sutur two anchor horizont mattress sutur chronic ankl instabl cai

D007593;D017844

T033;T023

36,266,689

endoplasm reticulum qualiti control pathway endoplasm reticulum associ degrad mechan regul n glycoprotein n glycan structur diatom phaeodactylum tricornutum tunicamycin inhibit first step protein n glycosyl modif howev physiolog transcriptom n glycom effect tunicamycin import marin diatom phaeodactylum tricornutum still unknown studi comprehens approach use studi effect tunicamycin stress result show cell growth photosynthesi signific inhibit p tricornutum tunicamycin stress solubl protein content signific decreas solubl sugar neutral lipid dramat increas orchestr balanc carbon nitrogen metabol stress g ml tunicamycin result differenti express erqc erad relat gene upregul gene involv erqc pathway activ anti oxidas differenti express gene relat erad mechan might import maintain homeostasi cell identif n glycan especi complex type n glycan structur enrich n glycan databas diatom p tricornutum provid import inform studi function n glycosyl modif protein whole studi propos work model erqc erad provid solid foundat depth studi relat mechan diatom express system

D060746;D017377

T204;T044

36,266,688

develop clinic valid ct base region modifi centiloid method amyloid pet standard centiloid cl method propos harmon quantifi global f label amyloid beta pet ligand use mri anatom refer howev need harmon quantifi region uptak ligand use ct anatom refer present studi develop valid ct base region direct comparison f florbetaben fbb f flutemetamol fmm centiloid rdccl

D000544;D000686

T047;T048

36,266,687

effect visual context visual vestibular mismatch reveal electroderm postur respons measur object criteria exist diagnosi treatment visual vestibular mismatch vvm

D004244;D014722

T184;T023

36,266,684

combin enhanc propionyl coa metabol pathway effici androstenedion product mycolicibacterium neoaurum product androstenedion ad phytosterol mycolicibacterium neoaurum multi step biotransform process requir degrad sterol side chain accompani product propionyl coa howev transient product larg amount propionyl coa accumul intracellular produc toxic effect sever inhibit ad product

D009161;D010840

T121;T123;T007;T109

36,266,683

effect vitamin insulin resist fast blood glucos pregnant women insuffici defici vitamin random placebo control trial gestat diabet one common metabol disord pregnanc studi report effect vitamin defici incid disord therefor purpos present studi determin effect vitamin supplement fast blood glucos fbg level fast blood insulin fbi level insulin resist index homa ir primari outcom symptom depress musculoskelet pain frequenc gestat diabet frequenc abort secondari outcom

D007333;D016640;D059352

T033;T047;T046

36,266,682

hpa mediat heterochromatin format promot antimicrobi respons pseudomona aeruginosa infect pseudomona aeruginosa gram negat bacterium caus sever infecti diseas divers host organ includ human effect therapeut option p aeruginosa infect limit due increas multidrug resist therefor critic understand regul host innat immun respons guid develop effect therapeut option epigenet mechan host regul antimicrobi respons p aeruginosa infect remain unclear use drosophila melanogast investig role heterochromatin protein hpa key epigenet regul mediat heterochromatin format antimicrobi respons pa high virul p aeruginosa strain

D011552

T047

36,266,681

evalu two social norm nudg intervent promot healthier food choic canadian groceri store object studi determin impact two nudg intervent custom produc purchas rural canadian groceri store pre post intervent observ studi design use sale data gather stagger implement two nudg base intervent encourag produc purchas groceri cart divid encourag shopper fill one third cart produc groceri cart plaqu inform mani fruit veget typic purchas store proport total sale account produc compar baselin implement first intervent phase implement first intervent addit second intervent phase baselin post implement intervent togeth relat increas absolut increas produc spend baselin post implement intervent p ci intervent phase specif produc spend show signific chang percentag produc spend baselin phase intervent relat increas absolut increas percentag produc spend phase phase intervent p ci simpl low cost nudg intervent effect increas proport total groceri spend produc studi also demonstr partnership local busi promot healthier food choic rural communiti canada

D000085943;D066262

T078;T073

36,266,680

orsai drosophila homolog human etfrf link lipid catabol growth control lipid homeostasi evolutionarili conserv process crucial energi product storag consumpt drosophila larva feed continu achiev rough fold increas size accumul suffici reserv provid energi nutrient necessari develop adult fli mechan control metabol program poor understood

D004331;D029721;D050356

T123;T044;T116;T204

36,266,679

repeat assess sodium na mri healthi human calf muscl preliminari result tissu sodium concentr subject addison diseas determin relax time sodium nucleus investig repeat quantit vivo tsc measur use sodium magnet reson imag na mri human skelet muscl explor discriminatori valu method compar tscs healthi subject patient addison diseas

D012964;D000224

T123;T196;T034;T047

36,266,678

mortal diseas circulatori system brazil relationship social determin focus vulner ecolog studi death diseas circulatori system ischem heart diseas declin slowli develop countri emphas probabl relationship determin social vulner

D017202;D002319

T022;T047

36,266,676

preval thyroid dysfunct jordan nation popul base survey object studi assess preval clinic subclin hypo hyperthyroid associ factor among jordanian adult

D006980;D007037;D013959

T047

36,266,675

use genet encod fluoresc biosensor interrog ovarian cancer metabol epitheli ovarian cancer oc lethal gynecolog malign patient present signific metastat burden particular adipos rich microenviron omentum recent evid highlight import metabol adapt enabl metastasi lead signific interest evolv arsenal tool use studi oc metabol studi demonstr capabl genet encod fluoresc biosensor studi oc focus organoid model better recapitul vivo tumor microenviron

D010051;D015374

T191;T059;T075

36,266,674

explain machin learn method respiratori oscillometri diagnosi respiratori abnorm sarcoidosi work develop mani machin learn classifi assist diagnos respiratori chang associ sarcoidosi base result forc oscil techniqu fot non invas method use assess pulmonari mechan addit accur result particular interest interpret explain use genet program sinc classif made intellig express also evalu featur import differ experi find discrimin featur

D000069550;D012507

T047;T066

36,266,673

genet modifi organ adapt regulatori framework evolv genom edit technolog genet modif live organ prosper activ research develop agricultur industri biomed applic three decad pass sinc first genet modifi product obtain transgenesi becom avail market regulatori framework across world abl keep date new technolog monitor safeti concern new genom edit techniqu open new avenu genet modif develop use put pressur framework discuss implic definit livinggenet modifi organ evolv genom edit tool obtain regulatori framework around world taken technolog account focus agricultur crop final expand review beyond commerci crop address live modifi organ use food industri biomed applic climat chang orient solut

D000072669;D018556

T063;T002

36,266,668

effect differ feed method gastrointestin function critic patient dfm gfc studi protocol random control trial enter nutrit major pathway nutrit patient requir critic care howev remain unclear whether intermitt continu feed better approach especi nasogastr enter nutrit via gastric tube therefor random control clinic studi design observ effect differ method critic ill patient

D016638;D011788

T078;T047

36,266,667

simultan femor head reduct osteotomi fhro combin periacetabular osteotomi pao treatment sever femor head aspher perth diseas purpos studi describ midterm clinic radiolog outcom concurr femor head reduct osteotomi fhro periacetabular osteotomi pao legg calv perth diseas lcpd patient major aspher femor head deform

D007873;D006618

T019;T047

36,266,666

associ co occur mental health problem hepat c status among young peopl inject drug rural new mexico inject drug use idu remain strongest risk factor hepat c virus hcv unit state hcv rate increas rural area among young adult peopl inject drug pwid peopl hcv pwid disproportion rate mental health problem howev unclear whether riski inject behavior mediat associ mental health problem hcv examin associ mental health problem hcv rural cohort young adult pwid goal inform rural servic deliveri

D015819;D055030;D015658;D006526

T098;T033;T047;T101;T048

36,266,665

combin associ triglycerid glucos index systol blood pressur caus cardiovascular mortal among general popul combin associ triglycerid glucos tyg index differ systol blood pressur sbp level caus cardiovascular mortal among general popul remain unclear

D005947;D002318

T123;T047;T121;T109

36,266,663

replic stress generat distinct landscap dna copi number alter chromosom scale loss major driver cancer chromosom instabl replic stress slow stall dna replic replic stress genom instabl connect known aphidicolin induc replic stress induc breakag common fragil site exact caus fragil debat acut genom consequ replic stress fulli explor

D056915;D009369

T045;T191;T086

36,266,662

identif window androgen sensit somat cell function human fetal testi cultur ex vivo reduc androgen action earli fetal develop suggest origin reproduct disord compris within testicular dysgenesi syndrom tds hypothesi support studi rat demonstr normal male develop adult reproduct function depend suffici androgen exposur sensit fetal period call masculin program window mpw main aim studi therefor examin effect manipul androgen product differ timepoint earli human fetal testi develop identifi exist time possibl window androgen sensit resembl mpw rat

D013735;D013737

T125;T023

36,266,661

male partner involv human immun defici virus test counsel prenat care visit bichena town westcentr ethiopia cross section studi transmiss human immun defici virus hiv mother child remain signific problem develop countri male partner involv hiv test counsel major entri point prevent mother child transmiss pmtct hiv studi aim assess male partner involv hiv test counsel prenat care visit bichena town westcentr ethiopia

D015658;D011251

T047

36,266,660

matern blood pressur associ placent dna methyl direct alter cell type composit matern blood pressur level reflect cardiovascular adapt pregnanc proper matern fetal exchang placenta sensit numer environment stressor matern hypertens pregnanc associ impair placent function increas risk children suffer cardiovascular respiratori diseas later investig chang placent dna methyl level cell type composit associ matern blood pressur could help elucid relationship placent fetal develop

D019175;D006973

T047;T044

36,266,658

target deliveri ros respons releas resolvin platelet chimer liposom amelior myocardi ischemia reperfus injuri resolvin rvd shown provid effect protect ischemia reperfus injuri multipl vital organ heart brain kidney howev clinic translat potenti system administr rvd treatment ischemia reperfus injuri great limit due biolog instabl lack target abil combin natur inflammatori respons reactiv oxygen speci ros overproduct reperfus injuri develop platelet bionic ros respons rvd deliveri platform result formul enabl target deliveri rvd injuri site hijack circul chemotact monocyt achiev local control releas mous model myocardi ischemia repefusuin mir injuri intraven inject formula result enrich rvd injur area turn promot clearanc dead cell product special proresolv mediat spms angiogenesi injuri repair effect improv cardiac function deliveri system integr drug bio protect target deliveri control releas endow great clinic translat valu

D008081;D015428

T046;T109

36,266,656

scale amoeba base process product cannabinoid precursor olivetol acid avail new biolog platform organ get access innov product process fundament progress biotechnolog bioeconomi amoeba dictyostelium discoideum repres novel host system recent employ discoveri new natur product cell factori product bioactiv compound phytochem howev essenti paramet evalu potenti new host system demonstr scalabl allow industri applic aim develop bioprocess product olivetol acid main precursor cannabinoid synthes recent engin discoideum strain

D000656;D004023;D002186;D061065;D001688

T121;T123;T204;T109

36,266,655

valu combin simpl anthropometr obes paramet bodi mass index bmi bodi shape index absi assess risk non alcohol fatti liver diseas bodi mass index bmi bodi shape index absi current independ risk factor non alcohol fatti liver diseas nafld aim studi explor valu combin two common obes index identifi nafld

D065626;D009767

T047

36,266,654

antivir activ mechan antifung drug anidulafungin suggest potenti promot treatment viral diseas sever fever thrombocytopenia syndrom diseas sfts caus novel tick born sfts virus sftsv list among top prioriti infecti diseas world health organ due high fatal rate lack effect antivir drug vaccin therefor rais urgent need develop effect anti sftsv drug improv diseas treatment

D000077612;D002044;D014777

T121;T047;T116

36,266,653

nadph sensor regul cell ferroptosi ferroptosi new form program cell death achiev great breakthrough cell biolog past decad howev regul ferroptosi yet identifi thorough latest studi publish natur cell biolog nguyen colleagu found new nadph sensor marchf e ubiquitin ligas mediat ferroptosi tumor growth anim develop find provid novel insight ubiquitin system energi metabol regul ferroptosi may open new avenu tumor treatment

D000079403

T043

36,266,652

influenc hyaluron acid intra articular friction biomechan studi whole anim joint cartilag mechan high stress tissu human bodi import part synovi joint joint cartilag lubric synovi fluid hyaluron acid ha main compon howev joint osteoarthr ha lower concentr molecular weight compar healthi joint recent year intra articular inject therapeut ha lubric becom popular therapi effect ha applic friction complet joint physiolog movement need determin

D002358;D006820

T123;T121;T024;T109;T122

36,266,651

global burden trend rotavirus infect associ death observ trend studi rotavirus lead global pathogen diarrhea associ mortal pose great threat public health age group studi aim explor global burden year chang pattern rotavirus infect associ death

D012400

T047

36,266,650

identifi stroke diagnosi relat featur medic imag report improv clinic decis make support medic imag report play import role communic diagnost inform radiologist clinician head magnet reson imag mri report provid evid wide use diagnosi treatment ischaem stroke high signal region diffus weight imag dwi imag mri report key evid correct identifi high signal region dwi imag help treatment ischaem stroke patient sinc multipl signal record head mri report appear part challeng identifi high signal region dwi imag mri report

D020521;D002545;D000083242

T047;T046

36,266,648

reduct posterior disloc hip prosthesi use modifi later posit maneuv retrospect clinic compar follow studi posterior disloc pd common complic total hip arthroplasti tha alli maneuv wide use method reduct howev classic maneuv disadvantag aim present studi investig whether modifi later posit mlp reduct maneuv provid easier safer method pd reduct alli maneuv

D006622;D006617;D019644

T061;T074;T190;T037

36,266,647

knowledg silesia adult inhabit regard prevent vaccin effect cardiovascular diseas protect vaccin import maintain health reduc suffer infecti diseas also vaccin prevent infecti diseas associ develop progress cardiovascular diseas

D002318;D003141;D014612

T129;T047;T121;T116

36,266,646

knowledg attitud percept medic student toward mental health univers uganda preval mental ill among medic student high gap remain knowledg given improv attitud percept toward mental health despit vast bodi literatur global studi conduct uganda assess level knowledg attitud percept among medic student uganda

D013337;D001523

T097;T048

36,266,645

compar genom transcriptom analys tran kingdom pathogen fusarium solani speci complex reveal degre compartment fusarium solani speci complex fssc compris fungal pathogen respons mortal divers rang anim plant genom divers transcriptom respons anim pathogen remain elucid sequenc assembl annot six chromosom level fssc clade genom aquat anim plant host origin establish pathosystem investig express data f falciform f keratoplasticum chines softshel turtl pelodiscus sinensi host

D005670

T004

36,266,644

overwork among resid physician nation questionnair survey result resid experi longest work hour among physician thus would benefici perform nationwid survey japan resid long work hour background factor promot upper limit work hour japanes resid aim studi studi assess state physician excess work hour background factor use questionnair survey

D007396;D010820

T065;T097

36,266,643

trend inequ matern child health health care uganda analysi uganda demograph health survey uganda made great stride improv matern child health howev littl known improv distribut across differ socioeconom categori health inequ chang time studi analys data demograph health survey dhs conduct uganda assess trend inequ varieti mother child health health care indic

D007306;D008427

T131;T058

36,266,642

comparison visual outcom diffract trifoc intraocular len refract bifoc intraocular len eye axial myopia prospect cohort studi assess compar efficaci safeti accuraci predict visual qualiti diffract trifoc intraocular len iol refract rotate asymmetr bifoc iol eye axial myopia

D007910;D009216;D018918

T061;T047;T074

36,266,641

perform biofir blood cultur identif panel bcid detect bloodstream pathogen associ resist marker systemat review meta analysi diagnost test accuraci studi earli identif bloodstream pathogen associ antimicrobi resist may shorten time optim therapi patient sepsi biofir blood cultur identif panel bcid novel multiplex pcr detect target direct posit blood cultur reduc turnaround time

D016470;D055624

T047;T007

36,266,640

comprehens analysi lncrna mediat cerna regulatori network key gene associ papillari thyroid cancer coexist hashimoto thyroid incid papillari thyroid cancer ptc concomit hashimoto thyroid ht gradual increas past decad studi aim identifi differenti express lncrnas tumor tissu ptc without ht confer better understand lncrna base compet endogen rna cerna network ptc ht

D062085;D050031;D035683;D013964

T123;T047;T191;T114

36,266,639

efficaci diet fatigu qualiti life disabl status multipl sclerosi patient rapid review meta analysi random control trial multipl sclerosi inflammatori neurodegen diseas peopl multipl sclerosi pwms experi chronic fatigu difficult deal therapeut great affect health relat qualiti life qol pwms awar lack general dietari advic relat diseas lead self experiment diet necessari provid object inform dietari intervent pwms aim provid object synthesi evid efficaci safeti specif diet pwms rapid review meta analys random control trial rcts examin symptomat fatigu mfis qol expand disabl status scale edss sever advers event

D011788;D009103

T078;T047

36,266,638

axillari vein thrombosi h caesarean section case report literatur review axillari vein thrombosi rare disord howev case axillari vein thrombosi short caesarean section report previous report case axillari vein thrombosi h caesarean section due unidentifi aetiolog

D056824

T047;T046

36,266,637

genom associ extend spectrum lactamas produc esbl ampc produc e coli small medium pig farm khon kaen provinc thailand thailand undergo rapid intensif livestock product small subsist farm medium size commerci farm coexist medium farm antimicrobi prescrib veterinarian wherea small farm antimicrobi use remain larg unsupervis impact differ well farm practic emerg composit antimicrobi resist gene arg remain larg unknown analyz genom extend spectrum lactamas produc esbl andor ampc produc escherichia coli recov human pig small medium farm khon kaen provinc thailand test genom wide associ identifi link arg host farm size pig isol small farm associ mcr qnr gene confer resist colistin fluoroquinolon respect contrast pig isol medium farm associ arg confer resist drug common use medium farm ie streptomycin esbl plasmid small farm co carri arg confer resist critic import antimicrobi frequent compar plasmid medium farm frequent arg combin includ bla ctx qnrs vs small medium farm respect bla ctx qnrs mcr vs bla ctx qnrs vs bla ctx qnrs mcr vs co locat plasmid arg confer resist critic import antimicrobi defin world health organ concern action curb spread urgent need legisl limit antimicrobi sale initi better inform farmer veterinarian appropri antimicrobi usag farm biosecur could help reduc antimicrobi use farm

D004927;D000890;D029968

T121;T047;T116

36,266,636

cardiac cephalalgia narrat review ichd criteria evalu cardiac cephalalgia unusu condit occur episod myocardi ischemia inform cardiac cephalalgia scarc characterist physiopatholog remain unclear aim provid narrat review clinic characterist physiopatholog cardiac cephalalgia evalu current diagnost criteria method search pubm undertaken studi cardiac cephalalgia publish th septemb summar literatur provid comprehens review headach characterist possibl mechan also evalu current intern classif headach disord third edit diagnost criteria base prior report case result total case found headach characterist variabl occipit locat throb pain frequent report headach accompani case cardiac symptom criterion b fulfil case criterion c criteria ca cb respect regard headach featur describ diagnost criterion c moder sever intens accompani nausea accompani photophobia phonophobia aggrav exert report case respect

D020773;D017202

T047

36,266,635

construct analysi sampl specif driver modul breast cancer import understand function impact somat mutat methyl aberr individu level implement precis medicin recent studi demonstr perturb gene interact network provid fundament link genotyp epigenotyp phenotyp howev unclear individu mutat affect function biolog network especi individu methyl aberr solv provid sampl specif driver modul construct method use order network theori hub gene theori identifi individu perturb network driven mutat methyl aberr

D053263;D009369

T191;T044

36,266,634

evalu diagnost perform h base block elisa specif detect pest des petit rumin domest sheep goat cattl camel pest des petit rumin virus pprv caus high devast diseas sheep goat pest des petit rumin ppr target global control erad serolog diagnost tool kit accur diagnosi ppr inher strength weak requir parallel valid optim across anim speci thus object studi evalu diagnost perform haemagglutinin base ppr block elisa hppr b elisa develop africa union pan african veterinari vaccin center specif detect anti pprv antibodi

D029021;D015511;D012757;D018107

T047;T005

36,266,633

aav ie mediat ucp overexpress acceler inner hair cell loss age vivo uncoupl protein ucp activ excess reactiv oxygen speci ros vivo dual effect reduc ros protect oxid stress reduc atp product regul cellular metabol ucp ros increas cochlea age relat hear loss arhl howev role ucp sensori hair cell arhl remain unclear

D006199;D034381

T033;T047;T025

36,266,632

health equiti characterist research explor unmet communiti mobil need older adult scope review unmet communiti mobil need older adult publish sinc announc un sustain develop goal synthesis describ health equiti characterist research identifi unmet communiti mobil need older adult

D000069576;D006233

T101;T080

36,266,631

quantit dce mri predict breast cancer recurr follow neoadjuv chemotherapi preliminari studi breast cancer patient treat neoadjuv chemotherapi nact risk recurr depend clinicopatholog characterist preliminari studi aim investig predict perform quantit dynam contrast enhanc dce mri paramet alon combin clinicopatholog variabl predict recurr patient treat nact

D020360;D001943

T061;T191

36,266,630

explor carer resili context dementia meta synthesi aim literatur review integr result qualit research resili experi famili carer peopl dementia pwd

D017028;D003704

T099;T098;T097;T048

36,266,628

reliabl evid guid decis make foot ulcer prevent diabet overview systemat review reliabl evid effect intervent prevent diabet relat foot ulcer essenti inform clinic practic well conduct systemat review synthesis evid relev trial offer robust evid decis make conduct overview assess comprehens util avail secondari evid reliabl sourc robust estim effect aim inform cost effect care pathway use econom model report detail overview prospero databas crd

D003920;D017719

T047

36,266,627

lymphocyt c reactiv protein ratio could better predict prognosi patient stage iv cancer system inflamm current regard hallmark cancer studi aim accur clarifi prognost valu various inflammatori marker patient stage iv cancer

D002097;D008175

T129;T191;T116

36,266,626

multi object data enhanc deep learn base ultrasound analysi recent deep learn base automat generat treatment recommend attract much attent howev medic dataset usual small may lead fit inferior perform deep learn model paper propos multi object data enhanc method indirect scale medic data avoid fit generat high quantiti treatment recommend specif defin main sever auxiliari task dataset train specif model task learn differ aspect knowledg limit data scale meanwhil soft paramet share method exploit share learn knowledg among model share knowledg learn auxiliari task main task propos method take differ semant distribut account train process main task collect ultrasound dataset thyroid nodul contain find impress treatment recommend label profession doctor conduct various experi dataset valid propos method justifi better perform exist method

D016571;D000077321

T170;T066

36,266,625

differenti distribut steroid hormon signal network human choroid retin pigment epitheli complex retin pigment epithelium rpe layer pigment cell lie neurosensori retina under choroid play critic role maintain function integr photoreceptor cell mediat communic neurosensori retina choroid prior studi demonstr neurotroph effect select steroid mitig develop progress retin degen diseas via array distinct mechan action

D019636;D012162

T047;T046

36,266,624

disentangl chang across time true stabil employe resili use latent state model debat within literatur whether resili consid stabl charact trait dynam changeabl process state two wide use measur assess resili connor davidson resili scale cd risc resili scale adult rsa aim studi evalu true stabil invari chang across time resili captur two measur use perspect latent state trait theori aim deciph cd risc rsa trait like state like address whether true differ resili particip increas decreas across time longitudin studi uk base employe n complet cd risc item version rsa item version aggreg analyz six parcel three occas six month latent state model latent state model indic specif residu factor util analysi suggest questionnair captur trait state compon resili result contribut discuss resili scale measur chang stabil defin resili trait like state like phenomena find also highlight issu resili scale measur whether resili quantifi construct

D055500

T055

36,266,623

helena low predict factor respons neoadjuv chemotherapi earli breast cancer express prognost predict impact earli stage breast cancer bc posit bc immunohistochemistri ihc score situ hybrid ish amplif treat target therapi concept low bc ihc score without ish amplif draw attent anti treatment recent shown efficaci subgroup aim explor respons neoadjuv chemotherapi nac low earli bc accord score without amplif

D020360;D001943

T061;T191

36,266,622

earli feed practic bodi mass index z score among saudi preschool cross section studi feed practic earli year may long last influenc eat behavior growth pattern bodi mass index bmi trajectori object studi character earli feed practic among mother saudi arabia examin associ child birthweight bmi z score bmiz preschool

D005247;D001942

T055;T058;T040

36,266,621

unmet need iron defici periton dialysi delphi consensus panel anaemia iron defici id common chronic kidney diseas ckd patient relat outcom grow interest role iron supplement ckd particular ferric carboxymaltos fcm also relat use erythropoiesi stimul agent esa despit greater knowledg id manag patient receiv haemodialysi pauciti data exist periton dialysi pd furthermor aim paper provid result nationwid italian survey id pd use delphi method

D006397;D000090463;D051436;D010530;D018798

T061;T121;T047

36,266,620

predictor nurs home admiss older popul belgium longitudin follow health interview survey particip studi examin predictor nurs home admiss nha belgium order contribut better plan futur demand nurs home nh servic health care resourc

D000544;D014549

T047;T046;T048

36,266,619

lesson learn implic earli therapi coronavirus diseas territori servic centr calabria region retrospect studi monoclon antibodi mab antivir approv earli therapi coronavirus diseas covid howev real life set difficulti prescrib therapi within day symptom onset recommend effect combin use drug hypothesis risk patient immunocompromis data support strategi limit

D000086402;D000086382

T005;T067;T047

36,266,618

innov approach base real world big data mine calcul sampl size refer interv establish use transform parametr non parametr method current direct method main approach establish refer interv ri howev hand studi describ effect sampl size establish ri estim sampl size describ novel approach estim sampl size establish ris use transform parametr non parametr method

D013974;D014284

T125;T121;T116;T109

36,266,617

detect ct radiculopathi measur root motor conduct time root motor conduct time rmct noninvas evalu status proxim root segment howev clinic applic remain limit wider studi regard use scarc aim investig associ ct level radiculopathi rmct

D011843

T047;T037

36,266,616

molecular characterist global lactamas produc enterobact cloaca genom analysi analyz characterist global lactamas produc enterobact cloaca includ distribut lactamas sequenc type sts well plasmid replicon

D016972;D001618

T007;T126;T116

36,266,615

effect comput aid row exercis system improv muscl strength function older adult mild knee osteoarthr random control clinic trial osteoarthr oa common age adult result muscl weak function limit lower limb knee oa affect qualiti life elder technolog support feedback achiev lower impact knee joint individu exercis could benefit elder patient knee oa herein comput aid feedback row exercis system propos effect improv muscl strength health condit knee function older adult mild knee oa investig

D020370;D000073678

T047;T056

36,266,614

surgic efficaci surviv predict patient unspecifi malign bone tumor surgic efficaci prognost outcom patient unspecif malign bone tumor umbt remain unclear studi address clinicopatholog featur prognost determin patient umbt nomogram develop clinician predict short long term outcom individu umbt surgeri improv outcom umbt patient receiv radiotherapi chemotherapi balanc confound bias

D049451;D001859

T081;T170;T191

36,266,613

effect topic timolol prevent radiat induc dermat breast cancer pilot tripl blind placebo control trial radiat therapi one standard method treatment breast cancer radiotherapi induc dermat rid common complic radiotherapi rt result less toler rt even discontinu treatment timolol adrenerg receptor antagonist present best wound heal effect chronic incur wound heal topic form timolol could effect prevent rid due role adrenerg receptor skin cell keratinocyt migrat well anti inflammatori effect timolol howev placebo control random trial avail confirm role current trial aim evalu efficaci topic timolol ww rid sever patient qualiti life qol

D001943;D011855;D013999

T121;T109;T191;T037;T047