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biomedical-topic-categorization-validation

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36,339,143
age specif associ environment factor epistaxi sever studi demonstr environment factor meteorolog factor air pollut close associ epistaxi howev age specif associ environment factor epistaxi yet evalu studi aim evalu associ individu meteorolog factor air pollut epistaxi age
D004844;D000393
T131;T046
36,339,142
viscer adipos tissu risk covid suscept hospit sever mendelian random studi coronavirus diseas covid rapid evolv global pandem observ studi found viscer adipos tissu vat increas likelihood wors clinic outcom covid patient wherea whether vat causal associ suscept hospit sever covid remain unconfirm aim investig causal associ vat suscept hospit sever covid
D000086382
T047;T067
36,339,141
lesson crisi opportun last public health chang covid pandem coronavirus covid global pandem wrought hardship disrupt live across strata human give rise varieti social psycholog medic challeng individu almost everi countri world yet difficulti pandem inflict forc us examin previous accept practic home work societi broad led innov chang way communic collabor novel approach contemporari challeng devis primarili allow continu product despit need social distanc offer secondari advantag could provid societi last benefit follow review outlin three aspect work life public health could experi last improv back lesson learnt current crisi
D058873;D000086382
T047;T067
36,339,140
effect mechan internet use physic health older peopl empir analysi base cfps use internet promot effect physic health older peopl howev previous studi most focus perspect overal popul limit direct effect ignor explor mechan action perspect older peopl base data china famili panel survey cfps studi found use internet signific effect physic health older peopl especi among popul group femal rural resid live central western region china addit studi also found use internet older peopl increas exercis frequenc therebi improv physic health therefor promot activ age studi propos increas popular internet among older peopl encourag introduct age appropri internet system sport facil creat onlin fit platform older peopl promot scientif fit program
D000084362;D015444
T061;T056;T169
36,339,139
examin influenc use behaviour scienc within uk local author public health qualit themat analysi deduct map com b model theoret domain framework behaviour scienc contribut toward improv public health receiv increas recognit yet translat insight public health practic research studi explor factor influenc use behaviour scienc within public health local author level
D011634;D001525
T090;T091;T055
36,339,138
effect social assist self rate health base china health retir longitudin studi charl data medic assist life assist signific negat influenc self rate health found via empir analysi base oprobit model negat influenc robust base substitut explain variabl propens score match found heterogen analysi negat influenc medic assist self rate health signific urban resid resid central china east china meanwhil negat influenc life assist self rate health signific urban resid resid central china east china northeast china studi provid empir evid improv health resid use medic assist life assist accur offer import polici enlighten formul appropri social assist polici
D011640
T064
36,339,137
lack evid viabil infect sar cov fecal specimen covid patient sar cov shed fece enter sewag system order implement effect control measur identifi new channel transmiss essenti identifi presenc infecti virus particl fece sewag studi attempt util molecular techniqu cell cultur anim model find infect sar cov fece covid patient find exclud presenc infecti virus particl suggest fecal oral transmiss may main mode transmiss larger scale initi nevertheless requir particular consid emerg new viral strain
D000086402;D000086382
T005;T067;T047
36,339,136
student covid vaccin prefer china discret choic experi studi use discret choic experi dce questionnair investig student vaccin prefer intrins extrins attribut
D000086663;D000086382
T200;T047;T067
36,339,135
household solid fuel use stroke incid evid nation cohort studi stroke one lead caus global mortal disabl specif studi focus associ household solid fuel use differ purpos incid stroke therefor explor associ household solid fuel use purpos switch incid stroke base nation prospect cohort studi particip includ studi exclus incid densiti stroke everi person year household solid fuel use simultan heat cook largest hazard effect stroke occurr hazard ratio hr confid interv ci signific linear trend p solid fuel use cook signific associ increas risk stroke occurr hr ci persist clean fuel use heat cook associ lower risk stroke occurr hr ci switch solid fuel clean fuel use cook associ lower risk stroke occurr hr ci compar persist solid fuel use effect measur improv household cook environ may necessari prevent incid stroke
D016902;D020521
T047;T069;T080
36,339,134
relationship health spend life expect renew energi china new evid vecm approach grow trend health spend renew energi consumpt china past decad posit implic health outcom life expect therefor main object studi empir analyz impact health expenditur renew energi life expect china use time seri data q q appli vecm approach data analysi result studi suggest long run associ health spend life expect renew energi increas health spend improv life expect renew energi consumpt also posit affect life expect china therefor govern alloc suffici fund health sector order attain higher life expect countri addit govern also provid incent consumpt product renew energi could help achiev sustain develop goal life expect
D057217;D002245
T081;T123;T197
36,339,133
sensit analysi rapid antigen test omicron sar cov variant detect nasopharyng swab sampl collect santiago chile covid pandem continu concern keep global health author alert rt pcr techniqu gold standard assay detect sar cov virus howev rapid antigen test rat wide use increas number test faster effici popul nevertheless appear new viral variant genom mutat associ greater contagi immun evas highlight need evalu sensit rat report evalu sensit sd biosensor roch panbio clinitest rat wide use santiago de chile detect omicron variant nasopharyng sampl npss predomin sar cov variant chile world sd biosensor roch show detect sensit viral amplif rang cq panbio clinitest show respect viral amplif rang cq detect sensit decreas sd biosensor roch panbio clinitest studi indic test rat high sensit detect omicron variant concern voc high viral load contrast sensit decreas low viral load therefor suggest limit use rat activ search method consid infect patient increas associ lower viral load sar cov anteced could prevent contagion outbreak reduc underestim current omicron variant circul local level
D000086402;D000086382
T005;T067;T047
36,339,132
compar burden brain central nervous system cancer china unit state predict futur burden brain central nervous system cns cancer repres major sourc cancer burden china unit state compar two countri epidemiolog featur brain cns cancer help plan intervent draw lesson
D001921;D009369
T023;T191
36,339,131
paradigm futur valu metavers intervent cognit declin cognit declin gradual neurodegen process affect genet environment factor doctor patient relationship healthcar cognit declin shallow medic world develop data scienc virtual realiti artifici intellig digit twin introduct concept metavers medicin brought altern complementari strategi intervent cognit declin articl technic analyz applic scenario paradigm metavers medicin field mental health hospit manag diagnosi predict prevent rehabilit progress delay assist life companionship supervis metavers medicin made primari progress educ immers consult dental diseas parkinson diseas bring revolutionari prospect non pharmacolog complementari treatment cognit declin mental problem particular demand non face face communic generat global covid epidem need uncontact healthcar servic elder increas paradigm self monitor self heal healthcar experienc elder metavers medicin especi meta platform meta communiti meta hospit generat reconstruct servic mode elder peopl futur map metavers medicin huge depend co construct communiti partner
D000086382;D060825
T047;T067;T048
36,339,130
interpret global variat toll covid case context nuanc hypothesi generat test januari covid pandem go affect popul worldwid potenti risk omicron variant futur variant still remain area activ investig thus ultim human toll sar cov extens variat toll among divers popul remain unresolv nonetheless extens literatur causal factor observ pattern covid morbid caus specif mortal emerg particular aggreg level analysi articl explor potenti pitfal attribut covid outcom specif factor isol examin divers set potenti factor interact
D000086382
T047;T067
36,339,086
characterist gut microbiota femal patient diabet microvascular complic explor characterist analyz gut microbiota femal patient diabet microvascular complic dmc
D000069196;D003924;D003925
T047;T007;T001
36,339,068
sex relat effect adrenerg drug condit pain modul random control cross doubl blind trial endogen pain inhibit investig use condit pain modul cpm cpm efficaci report influenc various factor gender cardiovascular autonom activ aim studi describ effect pharmacolog manipul autonom activ cpm efficaci
D018663;D059350
T121;T039;T184;T047
36,339,067
nonpharmacolog complementari intervent manag pain third molar surgeri umbrella review current meta analys provid nonbias complet assess evid meta analys inform us complementari nonpharmacolog treatment option manag pain third molar surgeri well highlight discord gap lack evid among meta analys
D008964;D010126
T023;T103
36,338,895
interplay metabol dysfunct associ fatti liver diseas chronic kidney diseas epidemiolog pathophysiolog mechan treatment consider recent propos nomenclatur chang non alcohol fatti liver diseas metabol dysfunct associ fatti liver diseas mafld result reapprais epidemiolog trend associ chronic diseas context mafld appear tight link incid chronic kidney diseas ckd associ may attribut multipl share risk factor includ type diabet mellitus arteri hypertens obes dyslipidemia insulin resist moreov similar molecular pathophysiolog mechan detect sinc inflamm oxid stress fibrosi gut dysbiosi high preval patholog state time line evid suggest genet predisposit mafld due gene polymorph pnpla rs g allel polymorph may also propag renal dysfunct concern manag avail treatment consider obes bariatr surgeri novel antidiabet agent glucagon like peptid receptor agonist sodium glucos co transport inhibitor appear benefici preclin clinic studi mafld ckd model moreov altern approach melatonin supplement farnesoid x receptor agonist gut microbiota modul may repres attract option futur look futur addit adequ size studi requir focus prevent renal complic patient mafld appropri manag individu concomit mafld ckd
D003924;D065626;D051436;D007333
T047;T046
36,338,894
covid hepatoren syndrom coronavirus diseas covid high infecti diseas emerg global pandem although primarili caus respiratori symptom affect patient covid shown multi organ manifest elev liver enzym appear common observ cours covid numer report liver injuri secondari covid infect establish patient pre exist chronic liver diseas cld like poorer outcom follow covid infect compar without cld co morbid diabet hypertens obes cardiovascular chronic kidney diseas frequent co exist individu live cld substanti popul may also live degre frailti mechan covid induc liver injuri postul hepatoren syndrom hrs occurr kidney dysfunct patient sever cldfulmin liver failur absenc anoth identifi caus usual marker sever decompens liver diseas select report hrs follow acut covid infect present although risk factor pathophysiolog mechan lead hrs covid infect follow covid treatment remain larg unestablish due relat lack novelti publish data evid discuss manag hrs high depend care intens care context emerg articl provid overview specul pathophysiolog mechan covid induc hrs propos strategi clinic diagnosi manag optim outcom scenario
D006530;D000086382;D008107
T033;T047;T067
36,338,893
journal includ correspond section letter editor provid use scientif inform evalu publish work well act addit level peer review furthermor letter good read materi especi involv debat author final letter relat short therefor inexperienc career research use opportun practic put togeth cogent argument howev far ideal situat letter main type articl base academ career
D010506
T170;T073
36,338,892
immun checkpoint inhibitor mediat coliti associ cancer overal surviv immun checkpoint inhibitor mediat coliti imc common advers event follow immun checkpoint inhibitor ici therapi cancer imc associ improv overal surviv os progress free surviv pfs data limit singl site predomin melanoma patient
D000074322;D008545;D003092
T129;T121;T116;T191;T047
36,338,891
effect covid liver experi singl center coronavirus diseas covid perhap sever global health crisi live memori alongsid respiratori symptom elev liver enzym abnorm liver function even acut liver failur report patient suffer sever acut respiratori diseas coronavirus pneumonia howev precis trigger form liver damag affect cours outcom covid remain unclear
D000086382;D011024;D017114
T047;T067
36,338,890
serum metabol profil target bile acid reveal potenti novel biomark primari biliari cholang autoimmun hepat primari biliari cholang pbc autoimmun hepat aih two unexplain immun diseas golden standard diagnosi diseas requir liver biopsi liver biopsi wide accept patient invas natur atyp liver histolog confus diagnosi view lack effect diagnost marker pbc aih combin increas matur metabolom technolog includ full contour metabolom target
D019693;D008105
T047
36,338,889
pitfal promis bile duct altern narrat review biliodigest anastomosi extrahepat bile duct intestin bile duct diseas gastrointestin reconstruct abolish duoden papilla function frequent caus retrograd cholang chronic inflamm caus liver dysfunct liver abscess even bile duct cancer although research conduct year direct repair bile duct defect altern bile duct substitut bds develop narrat review confirm understand bile duct altern develop explain clinic applic bdss near futur search pubm electron databas identifi studi conduct develop bdss decemb identifi studi english two independ review review studi larg anim case four type bdss prevail autolog tissu non bioabsorb materi bioabsorb materi other decellular tissu print structur etc studi bdss fail due obstruct lumen stenosi anastomosi nativ bile duct bds develop primarili control bile duct wound heal regener elucid bds expect clinic appli near futur incorpor bioabsorb materi allow regener bile duct outsid bds
D017734;D001649;D002761
T023;T047
36,338,888
risk factor small intestin adenocarcinoma common proxim small intestin frequenc primari small intestin adenocarcinoma increas still low frequenc approxim colorect adenocarcinoma consid small intestin occupi surfac area gastrointestin tract small intestin adenocarcinoma rare main site small intestin adenocarcinoma proxim small intestin base characterist dietari anim proteinslipid bile concentr implic report involv carcinogenesi sinc nutrient absorb proxim small intestin effect absorb intestin content suitabl explan small intestin adenocarcinoma common proxim small intestin proport aerob bacteria high proxim small intestin absolut number bacteria low addit length densiti villi greater proxim small intestin howev involv villi consid low number small intestin adenocarcinoma much smaller colorect adenocarcinoma hand reason low incid small intestin adenocarcinoma distal small intestin may immun organ resid genet diseas factor increas likelihood small intestin adenocarcinoma carcinogenesi experi posit small larg intestin exchang tumor still occur larg intestin mucosa often word influenc intestin content small larg differ epitheli properti small intestin larg intestin conclus small intestin adenocarcinoma rare compar larg intestin adenocarcinoma due natur epithelium reason assum diet trigger small intestin adenocarcinoma
D000230;D015179;D004379
T191
36,338,887
receptor advanc glycat end product axi gallbladd cancer forgotten connect reconsid compel evid deriv clinic experiment research demonstr crucial contribut chronic inflamm develop neoplasm includ gallbladd cancer regard data deriv clinic experiment studi demonstr receptor advanc glycat end product rage age axi play import role onset crucial long last inflammatori milieu thus support tumor growth develop age form biolog system food food deriv age also known dietari age known contribut system pool age bind rage activ multipl crucial signal pathway trigger thus favor secret sever proinflammatori cytokin also involv promot gallbladd cancer invas migrat present review aim highlight relev associ high dietari age intak high risk gallbladd cancer emerg data support dietari intervent reduc gallbladd cancer risk attract approach deserv much research effort
D017127;D005706
T123;T191;T109
36,338,886
sar cov induc liver injuri review articl high risk popul manifest mechan patholog chang manag outcom novel coronavirus diseas infect caus sever acut respiratori syndrom coronavirus sar cov declar global pandem million report case million death worldwid date although transit endem phase mani countri mortal rate overal prognosi diseas still abysm need improv evid show signific sar cov relat liver injuri review literatur various spectrum sar cov infect induc liver injuri possibl mechan damag hepatobiliari system review aim illustr latest understand regard sar cov induc liver injuri includ high risk popul characterist clinic manifest possibl pathogen mechan patholog chang current suggest clinic treatment various spectrum popul prognosi condit conclus sar cov patient liver injuri warrant close monitor associ sever poorer outcom infect
D000086382;D056487
T047;T067
36,338,873
awar attitud physician older adult routin vaccin scheme immun one main compon prevent medicin measur influenza pneumococc tetanus shingl vaccin recommend older adult routin studi aim show knowledg attitud physician older adult vaccin scheme
D007251;D000086382;D007252;D010820
T129;T121;T067;T109;T097;T047
36,338,826
case report potenti predict valu mmrmsi status pd express immunotherapi urotheli carcinoma immun checkpoint inhibitor ici shown encourag outcom lynch syndrom ls associ colorect cancer crc endometri cancer mismatch repair deficientmicrosatellit instabl high dmmrmsi h howev yet clariti safeti efficaci immunotherapi combin chemotherapi ls associ urotheli carcinoma uc report patient recurr metastat ls associ uc achiev sustain respons program death protein pd inhibitor combin chemotherapi month side effect immunotherapi could control manag find indic dmmrmsi status pd express uc may potenti predict valu respons pd target immunotherapi case support inclus combin andor monotherapi uc clinic studi use dmmrmsi status pd express potenti predict biomark assess therapeut respons
D002295;D001749;D003123;D015179
T047;T191
36,338,671
five year follow abca carrier show deterior retin function increas structur chang investig whether reduc retin function morpholog retin chang previous demonstr abca carrier remain stationari deterior time year follow explor carrier autosom recess trait also express weak phenotyp although expect autosom recess disord
D056915;D018528
T045;T116;T123;T086
36,338,670
sulforaphan recov cone function nrf depend manner middl age mice undergo rpe oxid stress sulforaphan sfn isothiocyan deriv crucifer veget therapeut efficaci numer anim model human diseas includ mous model retin degener howev despit dozen clinic trial compound remain test clinic treatment ocular diseas numer cellular activ sfn identifi includ activ nrf transcript factor induc batteri target gene product neutral oxid xenobiot stress nrf express function report decreas age test whether loss transcript factor limit therapeut efficaci sfn retin degener
D051267;D012162
T123;T046;T116
36,338,669
autosom domin retin pigmentosa incomplet penetr due intron mutat prpf gene identifi molecular mechan develop autosom domin retin pigmentosa adrp incomplet penetr isra muslim arab famili
D005136;D012174
T047;T116
36,338,668
oxid stress alter transcript local diseas associ gene retin pigment epithelium nuclear retent mechan wherebi excess rna transcript store event cell need quick respond stimulus maintain proper nuclear cytoplasm balanc import cellular homeostasi cell function mani mechan employ determin whether retain transcript export cytoplasm although extent tissu cell type intern extern stressor diseas pathogenesi affect process yet clear biochem activ tissu bodi retina must mitig endogen exogen stressor maintain cell health tissu function oxid stress believ contribut pathogenesi progress age relat macular degener amd inherit retin dystrophi ird produc intern biochem process well extern environment insult evalu effect oxid stress transcript local retin pigment epithelium rpe specif focus transcript relat rpe function diseas
D057026;D008268
T047;T025
36,338,667
structur function analysi snp rs g exon alpha crystallin gene len epitheli cell clarifi effect previous identifi singl nucleotid polymorph snp rs g exon alpha crystallin cryaa gene properti cryaa investig function human len epitheli cell hlec
D003459;D038202;D038201
T123;T116
36,338,666
clinic genet studi han chines pedigre sporad patient blepharophimosi ptosi epicanthus inversus syndrom investig molecular pathogenesi larg group han chines patient blepharophimosi ptosi epicanthus inversus syndrom bpes evalu correl phenotyp genotyp patient
D016569;D016649
T019;T047
36,338,665
associ igf polymorph exotropia pakistani cohort strabismus stbms multifactori ocular disord children lead misalign eye insulin like growth factor igf shown involv develop extraocular muscl myopia howev data limit genet associ igf stbms pakistan
D007334;D005099
T123;T047;T116
36,338,664
isol effici collagenas edta cultur corneal endotheli cell tissu engin corneal endothelium well cell therapi propos altern approach treatment corneal endotheliopathi approach requir vitro amplif function corneal endotheli cell cec goal studi compar two common isol method collagenas edta edta determin whether influenc cell viabil morpholog barrier function
D042783;D004728
T025;T024
36,338,609
alcohol negat emot side role stress neurobiolog alcohol use disord articl part festschrift commemor th anniversari nation institut alcohol abus alcohol niaaa establish first part nation institut mental health later independ institut nation institut health niaaa today world largest fund agenc alcohol research addit intramur research program niaaa support entir spectrum innov basic translat clinic research advanc diagnosi prevent treatment alcohol use disord alcohol relat problem celebr anniversari niaaa host day symposium alcohol across lifespan year evid base diagnosi prevent treatment research devot key topic within field alcohol research articl base dr sinha present event niaaa director georg f koob phd serv editor festschrift
D000437;D019973
T047;T048
36,338,577
inhibit cerebr ischemiareperfus injuri mscs deriv small extracellular vesicl rodent model systemat review meta analysi small extracellular vesicl sev secret mesenchym stem cell mscs shown great therapeut potenti cerebr ischemia reperfus injuri ciri studi first perform systemat review evalu efficaci mscs deriv sev experiment cerebr ischemiareperfus injuri studi identifi search databas januari august methodolog qualiti assess use syrcl risk bias tool anim studi data analyz use revman softwar result score studi qualiti rang total ten point meta analys show mscs deriv sev could effect allevi neurolog impair score reduc volum cerebr infarct brain water content attenu neuron apoptosi addit possibl mechan mscs deriv sev attenu neuron apoptosi inhibit microglia mediat neuroinflamm thus mscs deriv sev might regard novel insight cerebr ischem stroke howev mechanist studi therapeut safeti clinic trial requir systemat review registr prospero crd
D059630;D000067128;D015427;D002545;D020521
T026;T025;T037;T047;T046
36,338,568
resect solitari bone metastasi use preoper comput tomographi ct guid hook wire local case report secondari bone metastasi common evolut mani type cancer instanc need remov metastas improv prognosi patient bone metastasi invis non palpabl intervent difficult remov sure respect safe resect margin present case woman suffer breast cancer despit treatment primit lesion present solitari bone metastasi iliac crest lesion remov surgic could seen touch procedur due locat certain remov lesion surgeri respect safe resect margin perform pre oper comput tomographi ct guid hook wire local use method anatomopatholog examin confirm tumor natur lesion resect margin safe zone techniqu frequent use target soft lesion case breast lung cancer could therefor use way solid bone lesion
D003074;D008175;D001859
T047;T191
36,338,567
late diagnosi lassa fever outbreak endem area lead high mortal kenema district sierra leon februari march kenema district surveil team sierra leon receiv notif patient suspect lassa fever februari th march nd day investig start confirm diagnosi search addit case
D007835
T047
36,338,566
diagnost role stool tb pcr suspect tubercul coliti patient dr cipto mangunkusumo nation central general hospit cross section studi sign symptom tubercul tb coliti similar diseas inflammatori bowel diseas therefor find diagnost modal help differenti tb coliti diseas challeng studi aim find proport posit stool tb pcr suspect tb coliti subject also diagnost valu stool tb pcr compar colonoscopi histopatholog clinic evalu
D014376;D003092;D009169
T047;T007
36,338,565
minim invas surgic manag bi pedicular vertebr compress fractur case report vertebr compress fractur repres import part daili trauma spine surgeri manag codifi thank differ classif avail us combin compress fractur bi pedicular involv vertebra usual lead extens surgic manag main object case report share experi minim invas osteosynthesi techniqu perform type fractur patient year old fell high roof clinic sensori motor deficit present back pain visual analogu scale vas comput tomographi scan reveal compress fractur th lumbar vertebra l type accord ao classif also bi pedicular involv l underw minim invas surgic manag consist combin kyphoplasti percutan isol bilater intra pedicular osteosynthesi observ rapid sedat pain vas first day month bone heal achiev month comput tomographi ct scan month evid secondari displac materi sagitt frontal balanc satisfactori patient return clinic state like prior accid aim case propos less invas surgic altern manag bi pedicular vertebr compress fractur case combin kyphoplasti percutan isol bilater intra pedicular osteosynthesi result rapid recoveri surgeri return pre accid condit
D050815;D016103;D008003;D058498;D058866
T061;T204;T037;T047;T046
36,338,564
direct medic cost breast cancer treatment joliot curi institut aristid le dantec hospit dakar seneg incid breast cancer case worldwid case africa case seneg howev direct medic cost cancer treatment known seneg better resourc alloc import estim cost purpos studi analyz direct medic cost breast cancer treatment joliot curi institut dakar
D001943
T191
36,338,563
bednar tumour uncommon tumour skin report two case pigment dermatofibromasarcoma protuberan dfsp rare variant dfsp intermedi grade tumour due tendenc local reccur morpholog variant impos differenti diagnosi must know pathologist describ two case present pigment papulo nodular form involv back lower limb middl age elder femal histopatholog coupl immunohistochemistri yield daignosi bedner tumour surgic histopathologist need knowledg differenti pigment neoplasm skin ensur skip rare entiti
D018223;D012878
T191
36,338,560
intraop surpris evid bronchial rent lung surgeri case report among multipl caus tracheobronchi rent common iatrogen factor whenev surpris evid bronchial wall tear lung surgeri tracheal tube extub postop manag pose challeng report year old girl weigh kg case pulmonari koch present hydropneumothorax left side prolong cours mechan ventil gradual wean extub intens care unit icu implant cardiovert defibril icd situ howev chest x ray continu show loss bronchovascular mark high resolut comput tomographi hrct thorax reveal multipl cavitatori lesion hydropneumothorax upper lower lobe ground glass opac left side mediastin shift toward right side henc post left lung decort decort done use one lung ventil protocol fr left side doubl lumen endobronchi tube dlt check leak closur note exhal tidal volum unaccept low rent left main bronchus around x cm scar border detect rent repair tissu patch sutur surgeon procedur dlt exchang endotrach tube ett patient manag elect ventil post oper icu hour extub unev vigil monitor vital paramet close communic surgeon import detect manag periop complic lung surgeri elect ventil could play signific role heal big rent trachea bronchial area
D006872;D061810
T033;T059;T061
36,338,559
common coronari arteri occlus patient myocardi infarct coronari arteri diseas cad signific cardiovascular diseas cvd affect peopl worldwid studi aim determin main occlud coronari arteri patient myocardi infarct najran kingdom saudi arabia ksa
D000072658;D000072657;D054058;D054059;D009203;D003324
T047
36,338,558
medico demograph characterist outcom covid patient admit provinci hospit center west morocco current coronavirus diseas covid pandem emerg decemb china continu claim thousand live worldwid studi aim report characterist hospit outcom moroccan covid cohort identifi factor predispos patient hospit mortal covid conduct cross section studi symptomat covid patient refer covid ward settat provinci hospit octob confirm covid case defin posit detect sar cov genom use real time rt pcr assay perform nasopharyng swab patient demograph clinic characterist collect analyz use spss v univari follow multivari logist regress analysi perform identifi factor associ mortal due covid total patient report median age year iqr elder year men case fatal rate cfr male higher cfr femal deceas peopl male elder oxygen satur valu less admiss frequent recov one patient least one comorbid death older year cfr preval diseas diabet hypertens cardiac diseas common symptom present dyspnea fever cough multivari logist regress analysi show older age aor ci p cardiac diseas aor ci p associ higher mortal rate categor patient admiss accord risk factor identifi multivari also univari analys main dyspnea essenti help decid hospit prioriti strategi eventu reduc death risk
D000086382;D006331
T047;T067
36,338,557
occipit encephalocel associ anomali includ bilater eyelid coloboma bilater cleft lipcleft palat amniot band right leg absenc toe right left feet univers clinic graben butembo case report encephalocel malform due defect closur neural tube caus herniat brain tissu andor mening congenit skull defect size encephalocel vari centimet huge mass call giant encephalocel content usual consist degen neural tissu mening cystic part report case month old infant born non consanguin parent refer congenit occipit mass upon arriv clinic clinic examin reveal weight g head circumfer cm non bulg anterior fontanell present huge renit occipit mass measur xcm height cm found absenc eyelid bilater lip palat fissur constrict ring right leg absenc toe right left feet diagnosi amniot band syndrom made compon occipit encephalocel associ bilater palpebr coloboma bilater cleft lip palat amniot band right leg amput toe right left feet
D002971;D002972;D000652;D003103
T019;T047
36,338,555
warm autoimmun haemolyt anaemia complic simultan arteri venous thrombos case report novelti describ case report simultan develop arteri venous thrombosi previous healthi caucasian year old male newli diagnos warm autoimmun haemolyt anaemia wa aiha clinic present includ sensorimotor dysphasia right arm paresi abdomin pain swell left leg comput tomographi angiographi show partial occlus left middl cerebr arteri multipl infarct kidney spleen doppler ultrasound reveal thrombosi left poplit vein therapeut dose low molecular weight heparin institut togeth rituximab lead complet serolog haematolog remiss exact thrombot risk factor wa aiha still complet identifi general accept guidelin thromboprophylaxi exist sever onset wa aiha might point toward close associ haemolysi thrombosi rais question necess prophylact anticoagul
D000744;D054556;D020246;D013927
T047;T046
36,338,554
stereotact radiosurgeri cyberknif first case unit arab emir case report year old gentleman refer depart oncolog sever pain right ear radiat right side face imag reveal larg extra axial expansil lesion surround encas right cavern sinus extend right middl cranial fossa patient consult sever neurosurgeon recommend stereotact radiosurgeri cyberknif best non invas modal proxim critic structur brainstem made challeng surgic approach patient complet stereotact radiosurgeri cyberknif well one month treatment
D016634;D002426
T061;T030
36,338,553
primari diffus larg b cell lymphoma right kidney case report exist primari renal lymphoma prl kidney long debat due extranod locat lack lymphat channel primari renal lymphoma extrem rare account less frequent misdiagnos renal cell carcinoma rcc present year old man present right flank pain last week comput tomographi scan show larg isodens right renal mass small para aortic lymph node suspect rcc patient underw right radic nephrectomi lymphadenectomi unev postop outcom histopatholog immunohistochemistri show diffus larg b cell lymphoma patient receiv five cycl chemotherapi region radiotherapi within five year follow symptom recurr conclus even though prl rare tumor type effort made make preoper diagnosi prl treat system chemotherapi instead renal tumor requir nephrectomi
D002292;D007680;D016403
T191
36,338,550
postop meningocel anterior cervic discectomi arthroplasti case report anterior dural tear complic cerebrospin fluid csf leakag anterior meningocel rare inde literatur case describ anterior arthrodesi case post cervic arthroplasti describ manag type complic poor describ consensu present case patient underw cervic arthroplasti complic anterior meningocel month first surgeri imag reveal compress anterior meningocel relat clinic progress worsen revis surgeri consist combin closur gap fatti patch cover tachosil patch follow reinsert new cervic prosthesi last follow year patient show residu effect complic mobil disc prosthesi impair clinic result arthroplasti also satisfactori although type complic rare import consensus manag anterior meningocel experi tachosil appear satisfactori option manag complic
D008588
T019;T037;T020;T190
36,338,549
knowledg attitud hepat b infect among patient infect main liver clinic gambia adequ knowledg hepat b virus hbv infect import among patient infect impact health seek behavior studi therefor assess knowledg attitud among patient infect hbv gambia
D006509
T047
36,338,536
incid gastrointestin bleed transesophag echocardiographi use orthotop liver transplant risk upper gastrointestin bleed ugib transesophag echocardiographi tee patient high grade esophag varic ev undergo orthotop liver transplant olt poor understood retrospect singl centr cohort studi patient underw olt queen elizabeth hospit birmingham septemb septemb primari outcom determin incid ugib patient undergon olt ev receiv tee patient includ studi receiv tee incid post oper ugib patient receiv tee entir cohort patient evid ev patient ev ugib occur patient grade ev occur patient grade ev incid ugib patient receiv tee statist differ patient vs p conclus patient underw olt intra oper tee use associ low rate ugib even cohort high grade ev suggest tee relat safe method haemodynam monitor patient undergo olt
D016031;D004932
T061;T047;T020
36,338,535
interleukin high mobil group protein b earli sensit indic cell damag normotherm machin perfus prolong cold ischem storag porcin liver graft era organ machin perfus experiment model optim recondit margin liver graft need although relev cytokin signatur liver transplant analyz previous signific molecular monitor normotherm machin perfus nmp remain elus therefor develop porcin model cold ischem liver graft injuri prolong static cold storag scs subsequ nmp liver obtain ten minipig underw nmp h direct procur control group h scs graft prolong scs show signific elev ast alt gldh ggt perfus concentr reduc lactat clearanc bile analys reveal reduc bile product reduc bicarbon elev glucos concentr prolong scs cytokin analys graft perfus simultan demonstr increas pro inflammatori cytokin interleukin interleukin particular interleukin latter signific elev cytokin compar control peak earli h reperfus ngml vs ngml p also concentr high mobil group protein b signific elev h reperfus ngml vs ngml p show posit correl ast r gldh r level molecular analys recondit liver graft provid insight degre inflamm cell damag could therebi facilit futur intervent nmp reduc acut chronic graft injuri
D016031
T061
36,338,347
klotho amelior vascular calcif via promot autophagi vascular calcif vc regard common featur vascular age klotho defici report contribut vc amelior restor klotho express howev specif mechan involv remain unclear investig role autophagi process klotho inhibit vc clinic studi result indic base agatston score serum klotho level negat associ aortic calcif klotho defici mice exhibit aortic vc could allevi supplement klotho protein moreov autophagi increas aorta klotho defici mice protect vc final found klotho amelior calcif promot autophagi aorta klotho defici mice mous vascular smooth muscl cell mova calcifi condit find indic klotho defici induc increas autophagi protect vc klotho express enhanc autophagi amelior calcif studi benefici explor under mechan klotho regul vc import guid signific futur clinic studi treatment vc
D061205
T047
36,338,346
iron sulfur cluster key factor regul cell death cancer iron sulfur cluster ancient cofactor play crucial role myriad cellular function recent studi shown iron sulfur cluster close relat mechan multipl cell death modal addit numer previous studi demonstr iron sulfur cluster play import role develop treatment cancer review first summar close associ iron sulfur cluster cell death modal ferroptosi cuprotosi panoptosi apoptosi potenti role cancer activ drug resist review hope generat new cancer therapi idea overcom drug resist modul iron sulfur cluster
D007506;D009369
T123;T191;T116
36,338,345
molecular mechan epimedium extract ischem stroke base network pharmacolog experiment valid ischem stroke exhibit high morbid disabl mortal treatment ischem stroke limit despit intens research potent neuroprotect benefit epimedium ischem stroke gain lot interest nevertheless systemat research direct role mechan epimedium ischem stroke still lack network pharmacolog analysi coupl experiment verif util systemat evalu potenti pharmacolog mechan epimedium ischem stroke tcmsp databas use mine bioactiv ingredi epimedium target drugbank omim genecard databas employ identifi potenti target ischem stroke go kegg pathway analys also carri interact activ compon hub target confirm via molecular dock experiment ischem stroke model use evalu possibl therapeut mechan epimedium result bioactiv compound epimedium select hub target epimedium function ischem stroke identifi molecular dock result demonstr good bind il signal pathway reveal potenti signific pathway nf b mapkerk signal pathway involv furthermor vivo experi demonstr epimedium treatment could improv neurolog function reduc infarct volum addit epimedium reduc activ microglia astrocyt ischem penumbra hippocampus cerebr cortex follow ischem stroke western blot rt qpcr analys demonstr epimedium depress express il tnf il il also inhibit nf b mapkerk signal pathway studi appli network pharmacolog vivo experi explor possibl mechan epimedium role ischem stroke provid insight treatment ischem stroke
D034181;D000083242;D004365
T123;T047;T121;T002
36,338,344
poststrok seizur epilepsi review incid risk factor diagnosi pathophysiolog pharmacolog therapi stroke common caus epilepsi ultim lead decreas qualiti life affect ischem hemorrhag stroke lead poststrok epilepsi pse signific risk factor pse includ age age less year stroke sever measur nation institut health stroke scale nihss cortic involv genet factor trpm polymorph diagnosi pse made use imag modal blood biomark prognost criteria electroencephalographi eeg current gold standard diagnos pse new combin modal test increas diagnost specif literatur review uncov newli found mechan patholog poststrok epilepsi pathogenesi earli onset late onset character sequela neuron cellular hypoxia disrupt blood brain barrier respect interleukin respons increas activ glial cell caus gliosi hyperexcit neuron epinephrin high mobil group protein b downregul cd upregul hla dr impact patholog poststrok epilepsi inhibit normal neuron immun respons decreas level neuropeptid neurotransmitt act multipl uniqu mechan inhibit intracellular ca accumul act anti inflammatori also implement worsen progress poststrok epilepsi addit ca hippocamp reson neuron increas theta oscil associ poststrok epilepsi hypertens small vessel diseas may also implic tempor lobe epilepsi caus occult microinfarct furthermor review highlight potenti use statin primari prophylaxi pse multipl studi demonstr reduct incid use statin alon statin combin antiepilept drug a statin aspirin evid strong suggest second generat a superior treatment method pse data numer studi demonstr relat lack signific drug interact increas toler potenti superior maintain seizur free status
D019161;D004827;D020521
T033;T121;T047;T109
36,338,343
bradykinin galectin surviv deceas patient covid pneumonia increas promis biochem target still definit curat prevent strategi covid diseas crucial fulli comprehend pathogenesi covid infect develop expedi pharmacolog protocol impact cytokin storm covid sever one test hypothes role bradykinin various oxid stress marker relat research level determin immedi hospit admiss could use earli predictor develop diseas
D000086382
T047;T067
36,338,342
administr n acetylcystein regress fibrogen proinflammatori effect oxid stress hypertroph ligamentum flavum cell ligamentum flavum hypertrophi lfh major caus lumbar spinal stenosi lss hypertroph ligamentum flavum lf cell oxid stress activ intracellular signal induc express inflammatori fibrot marker studi explor whether healthi hypertroph lf cell respond differ oxid stress via examin level phosphoryl p p p induc nitric oxid synthas ino smooth muscl actin sma furthermor efficaci n acetylcystein nac antioxid revers fibrogen proinflammatori effect oxid stress hypertroph lf cell investig assess express level p p p p ino tgf sma vimentin collagen h treatment without nac oxid stress p p increas signific hypertroph healthi lf cell ino elev hypertroph lf cell reveal oxid stress negat affect hypertroph healthi lf cell hypertroph lf cell exhibit activ inflamm healthi cell h treatment p p p p ino tgf vimentin collagen increas signific nac administr revers effect oxid stress result form basi novel therapeut treatment lfh use antioxid
D017843
T023
36,338,341
arginas biolog therapeut implic diabet mellitus complic arginas ubiquit enzym urea cycl uc hydrolyz l arginin urea l ornithin two mammalian arginas isoform arginas arg arginas arg play vital role regul cell function insulin resist ir vascular complic via modul l arginin metabol nitric oxid product inflammatori respons well oxid stress basic clinic studi reveal abnorm alter arginas express activ strong associ onset develop diabet mellitus dm complic result target arginas may novel promis approach dm treatment increas number arginas inhibitor includ chemic natur inhibitor develop shown protect develop dm complic review discuss fundament featur arginas next regulatori role under mechan arginas pathogenesi progress dm complic explor furthermor review develop discuss challeng arginas inhibitor treat dm relat patholog
D001119;D003920
T047;T126;T116
36,338,340
dynamin relat protein involv mitochondri damag defect mitophagi nlrp inflammasom activ induc msu crystal excess generat reactiv oxygen speci ros great impact msu crystal induc inflamm drp depend mitochondri fission close associ mitochondri ros level howev whether drp signal contribut msu crystal induc inflamm remain unclear mice bone marrow deriv macrophag bmdms prime lps stimul msu suspens h protein level associ mitochondri dynam oxid stress mitophagi detect western blot bmdms load mitotrack green probe detect mitochondri morpholog measur mitochondri reactiv oxygen speci ros total ros level cell load respect mitosox dhe probe effect mito tempo antioxid target mitochondria drp inhibitor mdivi msu crystal induc periton arthriti mous model evalu studi reveal msu crystal stimul result elev mitochondri fragment bmdms treatment mito tempo drp knockdown signific amelior mitochondri damag induc msu crystal bmdms exposur msu crystal increas express automitophagi marker protein promot fusion mitophagosom lysosom lead accumul mitolysosom drp knockdown allevi defect mitophagi activ nlrp inflammasom msu crystal treat bmdms studi indic crosstalk mitochondri ros drp signal msu crystal induc inflamm drp signal involv msu crystal induc mitochondri damag impair mitophagi nlrp inflammasom activ
D063306;D058847
T123;T116;T043
36,338,339
tardiv dyskinesia develop superoxid dismutas level relev genet polymorph tardiv dyskinesia td preval movement disord signific impact patient schizophrenia scz due extend exposur antipsychot ap sever genet polymorph includ superoxid dismutas sod drd ser suggest explan patient suffer td method pubm search use search relev articl use follow keyword tardiv dyskinesia superoxid dismutas fifti eight articl retriev among includ review result overal studi retriev pubm studi investig associ td sod relat polymorph addit previous studi report associ td occurr genet polymorph conclus studi found risk td associ alter sod level sever genet polymorph includ val met drd ser
D000071057;D014150;D012559
T039;T121;T047;T048
36,338,333
reconstruct neural circuit use multiresolut correl light electron microscopi correl light electron microscopi clem use combin function molecular character neuron detail anatom map synapt organ describ multiresolut approach clem mrclem effici target electron microscopi em imag optic character cell maintain optim tissu prepar high throughput em reconstruct approach hing eas array section collect solid substrat repeat imag differ scale use scan electron microscopi match multiresolut em imag multiresolut confoc map aldehyd fix tissu featur visibl lower resolut em correspond well featur visibl dens label optic map fix tissu iter featur match start gross anatom correspond end subcellular structur use target high resolut em imag acquisit annot cell interest demonstr techniqu rang imag use link live optic imag em reconstruct provid walkthrough mous retin light em experi well exampl mous brain slice
D009474
T025
36,338,332
later superior oliv mous two system project neuron later superior oliv lso key structur central auditori system mammal exert effer control cochlear sensit involv process binaur level differ sound local understand lso contribut process requir knowledg resid cell connect auditori structur use standard histolog stain retrograd tracer inject inferior colliculus ic cochlea order character two basic group neuron princip periolivari po neuron project ic part ascend auditori pathway later olivocochlear loc intrins shell effer descend project cochlea princip intrins neuron intermix within lso exhibit fusiform somata disk shape dendrit arbor princip neuron bilater symmetr tonotop project ic intrins effer strict ipsilater project known tonotop previous public po shell neuron repres much smaller popul princip intrins neuron respect multipolar somata resid outsid lso non topograph bilater project po shell neuron appear widespread project target impli diffus modulatori function somata dendrit princip intrins neuron form laminar matrix within lso share quantifi similar align tonotop axi restrict project emphas import frequenc binaur process effer control auditori percept studi address expand previous find cell type circuit later project tonotopi lso mous
D065832;D007245
T023
36,338,148
tbcdc select constitut suppressor cd cell anti tumor respons cancer immunotherapi approach target signal pathway high synonym cd cd cell subset therefor often stimul nonspecif lymphocyt activ result cytotox otherwis healthi tissu goal studi identifi intrins modul basic lymphocyt activ pathway could discrimin bolster cd anti tumor effector respons use tbcdc null mous observ mark resist rang tumor type confer tbcdc defici moreov tumor bear tbcdc null mice receiv pd ctla monotherapi exhibit cure rate respect tbcdc express solid tumor cell tbcdc disrupt select augment cd cell activ cytotox effector respons adopt transfer cd cell alon suffici recapitul tbcdc null tumor resist mechanist tbcdc suppress cd cell activ anti tumor function intersect canon nf b pathway activ via regul mapk mediat ikk phosphoryl strike none cellular molecular perturb nf b pathway featur tbcdc null cd cell find identifi tbcdc mapk nf b signal axi viabl therapeut target promot cd cell anti tumor immun circumv cd cell associ cytotox nf b activ tumor cell
D016328;D009369
T129;T191;T116
36,338,147
human allogen cell kill patient deriv glioblastoma cell express high level dnam ligand adopt transfer cell novel immunotherapeut approach glioblastoma recent studi shown efficaci cell glioblastoma previous studi identifi ligand receptor interact cell glioblastoma cell identifi ligand receptor interact provid basi use cell treat glioblastoma vv cell generat peripher blood mononuclear cell healthi donor use artifici antigen present cell mica ulbp pvr nectin express patient deriv glioblastoma pdg cell analyz vitro cytokin secret cell cytotox toward pdg cell also analyz vivo anti tumor effect evalu use u orthotop xenograft glioblastoma model express ligand cytotox cell vari among pdg cell ifn granzym b secret level signific higher tcell co cultur high suscept pdg cell co cultur low suscept pdg cell cytotox correl signific express level dnam ligand pdg cell block dnam result decreas cell mediat cytotox cytokin secret intratumor inject cell show anti tumor effect orthotop mous model allogen cell show potent anti tumor effect glioblastoma dnam axi depend manner find facilit develop clinic strategi use cell glioblastoma treatment
D005909
T191
36,338,146
ecto calreticulin express multipl myeloma correl fail anti tumor immun respons bad prognosi immunogen cell death icd propos crucial process antitumor immunosurveil icd character exposur emiss damag associ molecular pattern damp includ calreticulin crt posit correl crt exposur total express improv anticanc immunosurveil found certain cancer usual accompani favor patient prognosi present studi sought evalu crt level plasma membran cd bone marrow mononuclear cell bmmcs isol patient vari degre multipl myeloma mm diseas examin possibl relationship basal crt exposur bone marrow immun microenviron well connect differ clinic marker data show increas level cell surfac crt associ aggress clinic featur wors clinic prognosi mm high crt express mm cell associ increas infiltr nk cell cd lymphocyt dendrit cell dc indic activ anti tumor immun respons also signific higher presenc immunosuppress treg cell increas express pd l myeloma cell
D037282;D009101
T123;T191;T116
36,338,145
bispecif cell engag kill resist cell kras gc blockad therapi coval kras gc inhibitor gci rapid chang treatment landscap advanc non small cell lung cancer drug resist remain clinic challeng two recent studi develop bispecif cell engag form link cell tumor cell select elimin gci resist cell
D002289;D008175
T191
36,338,005
summari matern mortal missouri histor perspect rate matern mortal unit state us higher industri nation per deliveri although matern mortal ratio decreas global emerg evid suggest matern mortal us increas one studi quot matern death everi year near miss one metric missouri rank th worst state matern mortal us
D008428
T081
36,338,000
anyon anytim anyth histori emerg medicin missouri histori emerg medicin em missouri reflect larger histori em burgeon specialti throughout unit state import uniqu contribut may general appreci discuss histor event import leader em mani could mention much inform come person interview physician room happen hope articl illumin progress made care critic ill injuri develop new specialti focus goal recogn mani emerg physician mention play larg role maintain grow academ program improv deliveri care administr legisl action navig specialti enorm challeng time
D004635;D010820
T091;T097
36,337,997
geriatr emerg medicin provid older missourian care need deserv emerg care older adult evolv effort meet need age popul pace improv qualiti cost effect emerg depart ed care older adult acceler develop geriatr emerg depart accredit geda research initi forg center lead innov collabor clic geriatr emerg care appli research gear innov two missouri ed highlight includ approach fall risk qualiti improv effort age popul multimorbid addit work need accommod grow popul implement sustain solut
D004632;D004635
T061;T058;T091;T093
36,337,996
emerg depart manag suicid ideat challeng mispercept hope behavior crise continu escal across unit state countri one highest suicid rate amongst develop nation us citizen die annual suicid mani suicid ideat seek care emerg depart hospit system resourc handl grow public health crisi evidenc base screen risk stratif treatment continu evolv standard improv suicid educ need broad appli across healthcar societi missouri state make concentr effort improv resourc care suicid ideat mani challeng need overcom time tell new statewid initi reduc missouri high rate suicid
D059020;D013405
T033
36,337,995
emerg medicin telehealth pandem becom gateway virtual care missouri telehealth provid novel bridg patient need avail resourc demand telehealth visit provid urgent medic servic virtual set telehealth use provid care patient despit geograph distanc emerg medicin quick adapt respons covid pandem util telehealth solv various problem tele triag use coordin covid test treatment greater util current emerg telehealth modal could increas access qualiti care missourian
D000086382;D017216;D004635
T047;T058;T091;T067
36,337,990
adhd diagnost trend increas recognit overdiagnosi preval attent deficit hyperact disord adhd seen consist rise recent year number spark debat reason observ trend concern diagnosi prescript stimul medic other rais issu diagnost dispar particular underrepres popul paper look side start histori adhd diagnost criteria chang earli concept alter attent hyperact th th centuri introduct diagnost statist manual mental disord dsm evolut defin today general broaden adhd diagnost time play role increas preval year reason increas awar physician public also believ play big role particular underrepres minor women howev continu dispar detect adhd group signific consequ patient social interperson profession life adhd left unrecogn untreat thought evalu accur diagnosi adequ treatment make big differ
D001289;D000697
T121;T048
36,337,989
tip spear emerg medicin missouri respons covid pandem covid pandem provid specialti emerg medicin opportun showcas mani knew along emerg physician ep well suit deal unknown quick adapt even incomplet limit inform resourc emerg physician missouri serv integr posit local nation intern missouri ep publish numer manuscript topic basic scienc clinic care devic innov also occur develop protect devic health care worker approach three year mark covid pandem burden clinic care still weigh heavili ep wave pandem brought challeng spur ep innov new way michigan ep brian zink md said anyon anyth anytim word correct sum emerg medicin other hesit care covid patient ep step despit uncertainti risk health emerg medicin led way continu innov push envelop emerg care
D000086382;D004635
T047;T091;T067
36,337,985
role multi dimension women empower agricultur improv nutrit status five children rural cash crop produc resourc limit set ethiopia littl known relat women empower agricultur index health nutrit outcom among five children ethiopia studi object examin women empower agricultur associ nutrit status children month rural cash crop produc resourc limit set ethiopia communiti base cross section studi conduct employ household women reproduct age group children five stratifi simpl random sampl use identifi household simpl random sampl use select villag household women empower agricultur measur abbrevi women empower agricultur index even overal multi dimension five domain empower index de signific predictor nutrit status children p sub indic pivot role child nutrit status disempower decis input product aor empower control incom aor avail livestock aor predictor child stunt wherea women disempower product decis seem beneficiari wast disempow women less like wast child empow women aor dietari agricultur divers particular livestock farm women empower product decis predictor better nutrit outcom children therefor concentr effort need toward strengthen multi dimension empower women agricultur emphasis women input product decis dietari agricultur diversif main livestock farm
D009752;D002664
T033;T040
36,337,846
molecular mechan under effect bimin kang mixtur allerg rhiniti network pharmacolog rna sequenc analysi allerg rhiniti ar high preval chronic inflammatori diseas respiratori tract previous studi demonstr bimin kang mixtur bmk effect allevi ar symptom reduc secret inflammatori factor mucin howev precis mechan under effect remain unclear
D065631;D004365
T123;T047;T121
36,337,845
imag evalu insert point accuraci retrograd intramedullari femor nail compar visual retrograd intramedullari nail placement femur fluoroscop retrograd intramedullari nail placement femur improv accuraci insert
D005594;D005264
T061;T037
36,337,844
effect thyme essenti oil liver injuri caus renal ischemia reperfus rat liver damag occur follow renal ischemia reperfus rir caus inflamm inflammatori cytokin activ kidney injuri studi thyme essenti oil te antioxid anti inflammatori properti use reduc liver damag induc renal ir male rat random divid equal group control rir rirt te rat receiv te pretreat dose mlkg one week anesthesia minut ischemia kidney anim close clamp reperfus perform hour anim serum isol evalu alkalin phosphatas alp aspart aminotransferas ast alanin aminotransferas alt paramet liver rat examin measur malondialdehyd mda nitric oxid glutathion gsh glutathion peroxidas gpx catalas cat express gene interleukin il tumor necrosi factor tnf caspas alp ast alt mda il tnf caspas increas signific rir group compar control group p gsh gpx cat decreas signific rir group compar control group p te caus decreas alp ast alt mda il tnf compar rir group caus increas amount gsh gpx cat rir group p studi show te antioxid anti inflammatori properti reduc liver damag induc rir
D046930;D009822;D015427;D008107
T109;T168;T033;T037;T047;T002
36,337,843
combin therapi polydeoxyribonucleotid microcurr muscl regener cast induc muscl atrophi rabbit aim studi evalu polydeoxyribonucleotid pdrn microcurr therapi mt function synergist cast immobil rabbit model atrophi calf muscl
D011089;D042461
T123;T116;T114
36,337,842
ideal configur distribut femor neck cannul screw high altitud popul finit element studi peopl high altitud area shape femor neck differ due differ live environ deduc optim insert angl posit cannul screw use three dimension finit element technolog patient high altitud
D005265
T037
36,337,841
antibacteri antioxid properti extract yucca baccata plant northwestern mexico pathogen bacteria bacteri agent oxid reaction involv health food preserv issu yucca baccata baccata sourc compound practic applic area investig remain limit
D027623;D012503
T002;T109
36,337,840
nfel potenti function gene regul immun microenviron human kidney cancer increas incid mortal renal cancer press find new biomark drug target diagnosi treatment howev one negat upstream regul p prognost immunolog role nfel renal cancer still bare known investig express prognost valu relev pathway nfel use dataset public databas includ cancer genom atlas program tcga genotyp tissu express gtex cancer cell line encyclopedia ccle ualcan furthermor analyz relationship nfel express immun microenviron use distinct method found nfel higher express kidney renal clear cell carcinoma kirc kidney renal papillari cell carcinoma kirp tissu adjac normal tissu addit identifi nfel one surviv relat factor kirc kirp enrich analys reveal nfel associ varieti immun relev pathway kirc relat infiltr ratio type immun cell kirc patient ultim demonstr nine signific enrich mutat tp met nfel express chang group elev express nfel renal cancer tissu versus normal tissu associ poor outcom patient besid nfel role regul immun microenviron renal cancer patient find studi provid potenti prognost biomark new drug target renal cancer
D007680;D002292
T191
36,337,839
computer simul educ physiotherapi student skill knowledg systemat review appli computer simul educ tool learn medic domain wide use mani countri review aim systemat investig computer simul tool develop educ physiotherapi student determin effect intervent
D007858;D013334
T061;T098;T062;T081;T041
36,337,838
product glucoamylas novel strain alternaria alternata solid state ferment glucoamylas essenti role biocatalyst various import industri pakistan synthes use various fungal bacteri strain differ ecocultur condit appli solid substrat ferment method ssf get highest yield glucoamylas alternaria alternata import fungus grow industri raw materi like wheat bran dri potato powder tea leav rice husk sugar cane peel use substrat among dri potato powder g prove best ferment media growth fungal strain well maximum glucoamylas produc moreov sever chemic physic state also explor solid substrat ferment techniqu glucoamylas yield highest glucoamylas product record hour incub incub chamber g raw substrat ml inoculum spore solut c temperatur ph phosphat buffer ph moisten agent starch concentr media addit nitrogen yeast extract carbon sourc maltos screen maximum glucoamylas titer umlmin highest specif activ umg cultur condit appropri growth alternata solid media product highest glucoamylas solid state ferment procedur could util commerci synthesi glucoamylas
D005087;D000528
T004;T126;T116
36,337,379
patient specif exercis develop end effector type upper limb rehabilit robot end effector type upper limb rehabilit robot ulrr connect patient one distal point make simpl structur less complex control algorithm avoid abnorm motion postur target anatom joint specif muscl given end effector type ulrr focus rehabilit combin motion upper limb chain assist patient perform collabor task intervent advantag exoskeleton type ulrr develop novel three degre freedom dof end effector type ulrr advantag mechan design design end effector type ulrr achiev three dof use four bar mechan lift mechan also develop patient specif exercis includ patient passiv exercis patient cooper exercis advantag develop patient cooper exercis simplifi human robot coupl system model singl spring system instead mass spring damp system effici improv respons speed control system term organ structur work introduc end effector type ulrr mechan design control system invers solut posit patient passiv exercis base invers solut posit linear posit interpol servo drive patient cooper exercis base spring model sequenc experi three healthi subject conduct result show good trajectori track perform patient passiv exercis show effect flexibl good real time interact perform patient cooper exercis
D012371;D000067190;D000071939
T061;T090;T074
36,337,378
implement evalu dynam neck brace rehabilit devic prototyp rehabilit assist devic headneck pain treatment allow dynam chang posit orient headneck moreov devic neither use simultan assess patient headneck condit paper aim design implement novel dynam headneck brace provid static dynam support andor traction symmetr asymmetr posit devic also provid assess headneck stiff purpos fulfil diagnos headneck disord devic use evalu rang motion symmetr traction capabl use two control modal addit also evalu determin stiff headneck throughout simul mechan model involv set spring devic could appli rightleft later bend headneck rang accuraci flexionextens rang accuraci respect throughout traction phase mm practic measur symmetr traction test show deviat compar calcul deviat greater flexionextens rather rightleft later bend mean obtain error less situat test accuraci stiff measur mechan model respect throughout perform stair step test paper present novel design dynam headneck brace provid support andor traction headneck posit capabl evalu headneck stiff cervic traction
D009333;D001915
T074;T029
36,337,280
third dose sarscov bntb mrna vaccin result improv immun respons hemodialysi patient hemodialysi hd popul vulner group coronavirus diseas covid pandem advanc chronic kidney diseas uremia associ weaker immun respons infect attenu respons vaccin aim studi studi humor cellular respons second third dose sever acut respiratori syndrom coronavirus sarscov bntb mrna vaccin hd patient follow respons time
D000086382;D014765
T129;T047;T121;T067
36,337,279
ulcer coliti progress retrospect analysi diseas burden use electron medic record ulcer coliti uc debilit inflammatori bowel diseas present knowledg regard uc diseas progress time limit
D003093
T047
36,337,278
toward granular molecular anatom map blood vasculatur singl cell rna sequenc make leap singl cell rna sequenc scrnaseq mark birth new era physiolog medicin within forese futur know exact gene express level differ cell type subtyp make bodi also learn particular cell state whether occur develop tissu repair diseas reflect precis chang gene express profound impact area life scienc scrnaseq may lead particular leap vascular biolog research blood vessel pervad fulfil essenti function organ function differ innumer organ specif vascular adapt special requir turn dictat differenti gene express two princip cellular build block blood vessel endotheli cell mural cell organotyp vasculatur essenti function divers think gas exchang urin excret xenobiot detoxif brain lung kidney liver respect addit organotyp vascular cell also differ along vascular arterio venous axi refer zonat differ essenti regul blood pressur flow moreov gene express base molecular chang dictat state cellular activ necessari angiogenesi vascular permeabl immun cell traffick ie function necessari develop inflamm repair differ level cellular heterogen creat near infinit phenotyp divers among vascular cell review summar exemplifi scrnaseq brought pictur year point take us
D042783;D009389
T046;T025
36,337,277
learn past plan futur scope review musculoskelet clinic research sweden aim studi determin scope musculoskelet msk relat clinic research sweden collat amount first tier fund receiv discuss strategi infrastructur support futur msk clinic trial sweden
D009140
T047
36,337,276
tissu base diagnosi system amyloidosi experi inform diagnost center uppsala univers hospit diagnosi system amyloidosi clinic challeng usual reli tissu biopsi develop diagnost method base presenc amyloid deposit abdomin subcutan fat tissu tissu also use determin biochem type amyloidosi perform western blot immunohistochem analys aid hous develop rabbit antisera mous monoclon antibodi mass spectrometr method develop select case diagnost outcom studi period obtain biopsi unfix subcutan fat tissu vari degre suspicion system amyloidosi contain amyloid deposit biochem natur amyloid determin western blot analysi specimen immunohistochemistri case
D058225;D000686
T047;T020
36,337,275
molecular tool monitor health diseas lucki coincid improv method molecular analys obvious central medic research describ herein work develop tool reveal molecular state health diseas recount got start endeavor earli work character genet variat led onto high throughput protein measur techniqu imag distribut protein activ state tissu also describ recent techniqu measur even exceed rare genet variant order monitor recurr diseas tumor patient
D025941;D011506
T063;T123;T116
36,337,274
distribut intraocular pressur swedish popul increas intraocular pressur iop pseudoexfoli pex major risk factor open angl glaucoma oag age relat neurodegen diseas signific import public health studi distribut iop popul pex common find
D005902;D019636
T047
36,337,272
covid outbreak forecast base vaccin rate tweet classif spread covid affect countri caus serious public health concern infect case increas despit effect vaccin effici quick surveil system covid help healthcar decis maker contain virus spread studi develop novel framework use machin learn ml model capabl detect covid accur earli stage estim risk mani model use social network site snss track diseas outbreak twitter one snss wide use creat effici resourc diseas real time analysi provid earli warn health offici introduc pipelin framework outbreak predict incorpor first step hybrid method word embed tweet classif second step consid classifi tweet extern featur vaccin rate associ infect case pass machin learn algorithm daili predict thus appli differ machin learn model svm rf lr classif lstm prophet svr predict hybrid word embed techniqu appli tf idf fasttext glove combin three featur enhanc classif furthermor improv forecast perform incorpor vaccin data input togeth tweet confirm case model perform accur show reliabl propos studi
D000086382;D061108;D014612
T121;T129;T116;T067;T170;T047
36,337,271
wild gees migrat optim algorithm new meta heurist algorithm solv invers kinemat robot paper propos new meta heurist algorithm name wild gees migrat optim gmo algorithm inspir social behavior wild gees swarm natur maintain special format long distanc migrat small group surviv reproduct mathemat model establish base social behavior solv optim problem meanwhil perform gmo algorithm test stabl benchmark function cec potenti deal practic problem studi five engin design problem invers kinemat solut robot test result show gmo algorithm excel comput perform compar algorithm practic applic result show gmo algorithm strong applic accur optim result competit challeng problem unknown search space compar well known algorithm literatur propos gmo algorithm enrich team swarm intellig optim algorithm also provid new solut solv engin design problem invers kinemat robot
D000066506;D012371
T090;T170
36,337,268
research behavior dynam motion plan method human vehicl social forc model interact motion plan unman vehicl pedestrian urban road environ key realiz autonom motion unman vehicl hybrid traffic scenario problem human vehicl interact motion plan model complex intersect studi unman vehicl articl first motion plan pedestrian unman vehicl establish accord social forc model behavior dynam model autonom vehicl ad crowd human vehicl interact forc establish virtual forc ad social forc model behavior dynam model respect improv social forc model behavior dynam model use motion plan pedestrian unman vehicl way establish model solv problem simpl pedestrian interact motion plan social forc model singl bodi motion plan behavior dynam thus provid strong support multibodi motion plan final interact motion plan trajectori pedestrian unman vehicl differ scene vehicl pedestrian motion plan trajectori effect avoid overlap cross avoid collis verifi effect feasibl propos model
D000063;D000069636
T098;T037;T067