PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,235,562 | predict role basal metabol rate bodi water distribut sarcopenia sarcopen obes link carbohydr sarcopen obes new categori obes specif condit sarcopenia studi aim find relationship basal metabol rate bmr bodi water distribut muscl health prospect role screen sarcopen obes sarcopenia role nutrient carbohydr relationship detect total elder subject recruit bodi composit estim bioelectr imped analysi sarcopenia defin asian work group sarcopenia cutoff valu determin receiv oper characterist curv mediat analys perform use spss process higher bmr bmrbodi surfac area bsa protect factor sarcopen obes p p sarcopenia p p elder peopl low extracellular water ecw intracellular water icw ecwtot bodi water tbw negat correl skelet muscl index smi intak dietari carbohydr peopl sarcopen obes lowest subject obes highest p result moder mediat model show bmr fulli mediat posit relationship carbohydr smi obvious popul abnorm bodi water distribut bmr bmrbsa potenti role predict higher risk sarcopen obes sarcopenia higher bmr lower ecwicw ecwtbw may benefit muscl health overconsumpt carbohydr especi gt amdr might risk factor obes moder dietari carbohydr intak might promot smi regul bmr bodi water distribut elder | D055948 | T047 |
36,235,561 | vitamin system sclerosi review background present paper aim review evid potenti implic vitamin pathogenesi manag system sclerosi ssc method perform review literatur look studi evalu potenti role vitamin analog ssc search pubm medlin embas cochran librari use follow string vitamin cholecalciferol system sclerosi scleroderma includ cohort studi case control studi random control trial observ studi result identifi nine pre clinic clinic studi pre clinic data suggest vitamin analog may suppress fibrogenesi clinic data concord report high preval hypovitaminosi osteoporosi ssc patient data associ clinic manifest phenotyp ssc convers far less consist conclus vitro data suggest vitamin may play antifibrot role ssc clinic data confirm find current lack hypovitaminosi common among ssc patient treat reduc risk osteoporosi | D010024;D012279;D012595;D014808 | T047 |
36,235,560 | adher mediterranean diet solubl klotho level valu food synergi age diet healthi age long intrigu issu current studi make head head comparison four dietari pattern associ solubl klotho klotho level age relat marker dietari data subject obtain nation health nutrit examin survey particip given score group accord four dietari pattern name mediterranean adher diet score mds low carbohydr diet score low fat diet low carbohydr diet subsequ associ klotho examin use linear regress analys addit calcul odd ratio age differ dietari pattern take lowest quartil klotho refer age mds dietari pattern reveal relationship klotho level posit associ coeffici p lt remain signific divid mds tertil tertil coeffici p lt tertil coeffici p lt group particip subset sex age bmi lower age observ higher mds group tertil p tertil p lt howev analyz separ mere three nine compon mds name alcohol consumpt coeffici p lt fruit coeffici p dairi product coeffici p show signific associ klotho mediterranean diet adopt food base approach merit valu complex interact food constitu bring benefit healthi age | D038441 | T061 |
36,235,559 | healthi lifestyl genet risk brain health gene environ interact studi uk biobank genet suscept lifestyl affect risk dementia littl direct evid associ preclin chang brain structur investig associ genet dementia risk healthi lifestyl brain morphometri whether effect elev genet risk modifi lifestyl chang use prospect data uk biobank particip median follow year defin healthi lifestyl accord american heart associ criteria bmi lt smoke healthi diet regular physic activ higher genet risk associ lower hippocamp volum beta cm ci total brain volum cm ci particip age year lt year healthi lifestyl associ higher total brain grey matter hippocamp volum lower volum white matter hyperintens effect modif age genet risk conclus advers effect high genet risk brain health found older particip adher healthi lifestyl recommend benefici regardless age genet risk | D003704;D059647 | T045;T048 |
36,235,558 | inhibit glucosidas pancreat lipas properti mitragyna speciosa korth havil kratom leav kratom mitragyna speciosa korth havil use reduc blood sugar lipid profil tradit medicin mitragynin major constitu kratom leav previous data blood sugar lipid alter effect kratom limit studi phytochem analys mitragynin hydroxymitragynin quercetin rutin perform kratom extract effect glucosidas pancreat lipas activ investig kratom extract mitragynin lc msms analysi show mitragynin quercetin rutin content kratom extract differ ethanol extract exhibit highest total phenol content tpc total flavonoid content tfc total alkaloid content tac addit compar methanol aqueous extract ethanol extract show strongest inhibit activ glucosidas pancreat lipas compar anti diabet agent acarbos mitragynin show potent glucosidas inhibit less potent activ pancreat lipas inhibit analysi glucosidas pancreat lipas kinet reveal mitragynin inhibit noncompetit competit effect respect combin mitragynin acarbos result synergist interact glucosidas inhibit result establish potenti mitragynin kratom herbal supplement treatment prevent diabet mellitus | D032065 | T002 |
36,235,557 | possibl measur improv particip respons qualiti japan nation health nutrit survey result workshop local govern personnel charg survey increas particip rate crucial ensur repres nation survey result popul studi aim identifi measur could taken local govern personnel charg nation health nutrit survey nhns japan improv particip rate subject twenti one health personnel work local govern particip train cours nation institut public health qualit data collect workshop discuss problem seem affect particip rate identifi possibl solut content code group creat categori use jiro kawakita kj method data analysi research combin review code categori measur could improv particip rate divid follow categori standard survey method investig skill survey organ venu set access target household time survey respons investig confirm meal content report nutrit intak status survey rewardsincent possibl reward feedback survey result survey practic covid pandem find repres viabl initi local health personnel increas particip rate nhns | D000086382;D009111 | T047;T092;T067 |
36,235,556 | increas habit frequenc daili live patient acut anorexia nervosa strict eat routin frequent rigid behavior pattern common observ patient anorexia nervosa recent theori propos behavior may reinforc initi later becom habitu date howev research over focus eat disord ed relat habit cours seven day appli ecolog momentari assess ema investig habit frequenc strength ed specif food intak ed unspecif hygien habit daili live sampl n n healthi control hc result hierarch model reveal habit signific like patient compar hc categori independ furthermor lower bodi mass index bmi associ increas habit frequenc studi strengthen habit theori show relev habit beyond ed specif behavior domain also support develop innov therapeut intervent target habitu behavior ed | D000856;D001068 | T047;T048 |
36,235,555 | decreas vitamin c intak low serum vitamin c level risk us adult diabet vitamin c vc intak serum vc fast plasma glucos ac level adult men adult women type type diabet nhane databas analyz hypothesi low vc intak serum vc level may health risk us adult diabet analys reveal total vc intak estim averag requir ear increas vc intak serum vc level invers associ marker pre diabet type diabet name fast plasma glucos ac level risk type diabet increas adult vc intak ear vc supplement odd ratio ci ci respect median survivor year diabet adult lower defici serum vc shorter diabet adult normal serum vc mortal risk type diabet low vc intak andor defici serum vc level elev compar adequ vc intak normal serum vc hr ci ci respect observ declin vc intak deleteri consequ low serum vc us adult diabet suggest encourag vc intak includ vc supplement mgday may benefici pre diabet diabet us adult | D003924 | T047 |
36,235,554 | mediat effect food content watch motiv watch time nutrit quotient adolesc seoul korea food relat content vari wide increas popular use various media teenag easili access food content could affect eat habit studi conduct confirm effect watch motiv relationship food content watch time eat habit among adolesc seoul korea exact particip survey food content watch status includ watch time watch motiv nutrit quotient adolesc nq questionnair use confirm eat habit exploratori factor analysi conduct classifi watch motiv subfactor parallel multimedia model use analyz effect watch motiv relationship food content watch time eat habit result studi follow factor analysi watch motiv classifi inform acquisit emot satisfact enjoy influenc food content watch time nq score inform acquisit motiv posit signific wherea emot satisfact motiv negat signific enjoy motiv indirect affect relationship food content watch time nq score henc attent paid mediat factor analyz relationship watch food relat content eat habit develop distribut content meet view motiv help improv adolesc eat habit | D005247;D009042 | T055;T078;T041;T040;T080 |
36,235,553 | infant feed choic first post natal month anthropometri age seven year follow random clinic trial belgrad munich infant milk trial bemim random healthi term infant either protein reduc intervent infant formula group lactalbumin enrich whey long chain polyunsatur fatti acid control infant formula cf group non random breastf group bf studi refer assess long term effect infant feed choic growth measur age seven year weight stand height head circumfer percent bodi fat use skinfold bioelectr imped determin standard method total children complet initi studi particip seven year follow children three studi group differ anthropometr measur includ bodi mass index cf bf kgm mean sd igf serum concentr determin age month contribut explain varianc weight p height p bmi p z score age seven year wherea insulin level four month differ feed choic first four month life lead higher energi effici increas growth affect later growth outcom earli school age diet induc modul igf first month life may last program effect later growth | D007227;D061385 | T121;T061;T040 |
36,235,552 | haskap berri leav lonicera caerulea l favor potenti medic use present research evalu medic use potenti lonicera caerulea leav wast plant cultiv berri studi screen activ includ leav five varieti lonicera caerulea atut duet wojtek zojka jugana microbiolog analysi confirm safeti use lonicera caerulea leav without signific stabil lonicera caerulea leav standard carri base result chromatograph analysi show differ content activ compound logan chlorogen caffeic acid rutin attribut biolog activ lonicera caerulea leav varieti test differ content total polyphenol content chlorophyl carotenoid also confirm screen biolog activ five lonicera caerulea leaf varieti carri concern possibl inhibit activ glucosidas lipas hyaluronidas well antioxid potenti determin defin profil biolog activ lonicera caerulea leav make possibl indic raw materi essenti materi support prevent treatment type ii diabet howev research show test enzym strong inhibit varieti jugana health promot potenti lonicera caerulea leav correl highest chlorogen acid rutin content varieti jugana | D003924;D031239 | T047;T002 |
36,235,551 | valid nutrit rank system food pantri use healthi eat index charit food organ began adopt healthi eat research nutrit guidelin rank individu food tier eg green yellow red base food nutrient profil studi aim valid tier rank system healthi eat index hei develop formula summar percentag tier rank food overal nutrit qualiti index correl hei use secondari data food select client minnesota food pantri n client cart generat hei score percentag green yellow red food cart valid test associ hei score percentag tier rank food compar mean tier rank variabl use quintil hei score hei score posit associ percentag green food negat associ percentag red food next use statist learn generat weight maxim correl tier rank variabl hei score use weight creat index index demonstr moder strong correl hei use singl measur summar overal nutrit qualiti set tier rank food | D000072001;D005502 | T055;T061;T168;T033 |
36,235,550 | possibl improv bioavail resveratrol polydatin deriv polygoni cuspidati radix result prepar electrospun nanofib base polyvinylpyrrolidonecyclodextrin low bioavail resveratrol polydatin obtain polygoni cuspidati extract limit applic pro health properti nanofib attract increas attent nutrit deliveri due special properti includ increas dissolut permeabl affect bioavail therefor justifi obtain nanofib polygoni cuspidati extract show antioxid anti inflammatori properti result presenc stilben analog polygoni cuspidati extract especi resveratrol polydatin first stage work use design experi doe approach polygoni cuspidati extract methanol temperatur c cycl obtain show best antioxid anti inflammatori properti use polygoni cuspidati extract substrat nanofib obtain electrospin identif nanofib confirm basi analysi chang xrpd diffractogram sem pictur ftir atr spectra obtain nanofib polygoni cuspidati extract signific improv solubl resveratrol polydatin approx fold compar pure substanc consequ penetr coeffici test resveratrol polydatin also increas propos strategi prepar nanofib polygoni cuspidati extract innov approach better use synergi biolog action activ compound present extract especi develop nutraceut base use select stilben | D003505;D004365;D057139;D013267 | T073;T121;T109;T123;T130 |
36,235,549 | effect green tea extract ingest fat oxid exercis menstrual cycl pilot studi women fat oxid exercis chang menstrual cycl studi aim investig effect green tea extract gte ingest fat oxid exercis depend menstrual cycl phase ten women regular menstrual cycl particip random doubl blind crossov studi gte placebo administ menstrual cycl follicular phase fp luteal phase lp particip cycl min maxim workload respiratori gas analysi perform serum estradiol progesteron free fatti acid plasma noradrenalin blood glucos lactat concentr assess exercis fat oxid carbohydr oxid respiratori exchang ratio rer calcul use respiratori gas fat oxid exercis signific higher fp lp placebo p lt differ phase gte carbohydr oxid serum free fatti acid plasma noradrenalin blood glucos lactat concentr signific differ phase either trial result suggest gte ingest improv decreas fat oxid lp | D001786;D011374 | T121;T109;T123;T125 |
36,235,548 | zinc fortif current trend strategi zinc structur cofactor role affect broad rang critic physiolog function includ growth metabol immun neurolog function zinc defici widespread among popul around world may therefor underli much global burden malnutrit current zinc fortif strategi includ biofortif fortif zinc salt primari focus stapl food wheat rice product howev zinc fortif present uniqu challeng due influenc phytat protein zinc absorpt success zinc fortif strategi consid impact zinc bioavail whole diet zinc absorb food shift plasma zinc concentr minor howev co absorb zinc food may preferenti direct zinc cellular compart zinc depend metabol process primarili occur although current lack sensit biomark zinc nutrit status reduc capac assess impact fortifi food zinc new approach assess zinc util increas articl review tool avail assess bioavail zinc approach evalu zinc nutrit status popul consum zinc fortifi food recent trend fortif strategi increas zinc absorpt | D044342;D015032 | T121;T047;T123;T196 |
36,235,547 | vitamin bind protein bioavail free oh mortal systemat review meta analysi observ studi report invers associ serum total hydroxyvitamin oh concentr mortal evolv evid indic howev bioavail free oh may even better predictor mortal conduct systemat review meta analysi summar epidemiolog evid associ vitamin bind protein vdbp albumin bound bioavail free oh mortal | D014808;D014809 | T047;T123;T116 |
36,235,546 | random trial earli enhanc parenter nutrit later neurodevelop preterm infant retrospect studi indic parenter provis calori protein lipid first week life associ improv later neurodevelop aim determin whether infant random enhanc parenter nutrit protocol improv development outcom month correct age ca total preterm infant lt week gestat age lt g random receiv enhanc parenter nutrit pn standard pn first week life enhanc group receiv higher glucos infus rate intralipid neurodevelopment outcom includ pattern revers visual evok potenti vep month ca n bayley scale infant develop bsid n n month ca p latenc longer intervent group indic slower process speed vs ms p associ hold multivari analysi adjust potenti confound variabl bsid score associ enhanc pn higher enter energi protein intak regardless random group associ faster process speed month ca p enhanc earli pn associ improv neurodevelop howev first week enter calor protein intak associ improv speed process | D007234;D010288 | T061;T100;T033 |
36,235,545 | impact covid short medium term prescript enter nutrit general popul vs older peopl communiti madrid spain aim analys impact covid prescript enter nutrit support expenditur communiti madrid spain compar pre pandem data general popul vs elder analys offici electron prescript public hospit communiti madrid popul year age higher prescript nutrit supplement p lt vs age group differ age group compar age group p first wave covid first time real awar virus spain similar way first peak prescript enter nutrit march second peak prescript observ age group juli pronounc decemb march april follow year f p last peak correspond summer autumn year p year vs p year vs relationship increas prescript enter nutrit covid case observ high protein high calori dietari therapi prescrib patient without diabet entail higher cost communiti madrid conclus covid signific affect prescript nutrit support especi popul year age | D000086382;D004750 | T061;T047;T074;T067 |
36,235,544 | posit associ plasma level vitamin c invers associ vcam total adiponectin bone miner densiti subject diabet popul studi shown trend decreas vitamin c status increas preval osteoporosi patient diabet non diabet peopl dietari vitamin c consumpt link improv bone miner densiti bmd epidemiolog studi vcam adiponectin known activ osteoclast increas bone loss | D003920;D010024 | T047 |
36,235,543 | associ mushroom alga consumpt mortal among chines older adult prospect cohort studi mushroom alga import sourc dietari bioactiv compound associ mortal remain unclear examin associ mushroom alga consumpt subsequ risk caus mortal among older adult studi includ older adult age year chines longitudin healthi longev survey consumpt mushroom alga baselin age assess use simplifi food frequenc questionnair ffq use cox proport hazard model estim hazard ratio hrs confid interv cis person year follow total death case document adjust demograph lifestyl dietari factor particip consum mushroom alga least per week lower risk caus mortal rare consum time per year hr ci compar particip rare intak age studi baselin averag age maintain regular consumpt time lowest hazard mortal hr ci find support potenti benefici role long term consumpt mushroom alga reduc caus mortal among older adult studi warrant evalu health benefit longev specif type mushroom alga | D000363 | T004 |
36,235,542 | emerg role nicotinamid ribosid health diseas among nad precursor nicotinamid ribosid nr gain attent potent nad enhanc agent recent discov vitamin b demonstr excel safeti efficaci profil oral bioavail human boost intracellular nad concentr use nr shown provid protect effect broad spectrum patholog condit neurodegen diseas diabet hear loss review integr overview nr research present role nr play nad biosynthet pathway introduc follow discuss synthesi nr use chemic enzymat approach nr effect regul normal physiolog pathophysiolog also present focus studi publish last five year | D009243;D009536 | T121;T109;T123;T127;T114 |
36,235,541 | amino acid profil nutrit evalu fresh sweet waxi corn three differ region china studi conduct compar analysi amino acid composit chines huangnuo fresh sweet waxi corn three differ provinc china inner mongolia jilin heilongjiang provinc moreov establish nutrit evalu system base amino acid profil evalu compar rank fresh sweet waxi corn plant differ region total amino acid quantifi amino acid composit fresh sweet waxi corn analyz evalu amino acid qualiti determin amino acid pattern spectrum chemic evalu includ cs aa eaai bv u u ni f predict per pdcaa flavor evalu amino acid match degre evalu result factor analysi result show protein content fresh corn inner mongolia highest mgg factor analysi result digest absorpt effici fresh corn best amino acid profil fresh corn closest evalu model spectrum result divers evalu fresh corn best fresh corn essenti amino acid content total amino acid fresh corn divid three princip compon factor analys function princip compon leu pro glu ile ser met val tyr thr regulatori princip compon lys gli ala asp arg trp protect princip compon phe score three princip compon comprehens score fresh corn highest follow amino acid nutrit valu fresh corn highest sampl | D000596;D003313 | T116;T002;T121;T123;T168 |
36,235,540 | hyaluronan oligosaccharid coat paclitaxel casein nanoparticl enhanc stabil antitumor activ studi aim develop specif molecular weight hyaluron acid oligosaccharid coat paclitaxel load casein nanoparticl ha pt cas nps via chemic conjug increas stabil antitumor effect optim ha pt cas nps hacasein obtain mean size nm entrap effici ha pt cas exhibit satisfactori stabil c day c h paclitaxel retain rate respect signific higher pt cas c h c h ha pt cas exhibit high effici inhibit tumor owe enhanc stabil ha oligosaccharid barrier compar gml cis platinum mice experi show tumor inhibit ha pt cas intraven administr signific higher pt casein therefor work provid effect carrier drug deliveri via ha oligom coat modif | D053758;D017239 | T121;T109;T073 |
36,235,539 | thyroid extrathyroid requir iodin selenium combin evolutionari patho physiolog approach iodid antioxid oxid thyroid hormon constitu selenoprotein need triiodothyronin synthesi deactiv iodin releas also protect thyroid extrathyroid tissu hydrogen peroxid use peroxidas partner system system produc thyroid hormon reactiv iodin exocrin gland kill microb exocrin gland recycl iodin high urinari clearanc requir constant dietari suppli unlik thyroid disbalanc iodin selenium explain relat thyroid autoimmun diseas tad cancer thyroid exocrin organ notabl stomach breast prostat seafood iodin unconstrain selenium constrain terrestri food contain littl iodin selenium rang high defici high toxic iodin vs tad u shape low selenium relat tad oxid stress low selenium infect disbalanc iodin selenium may generat cancer thyroid exocrin gland tradit japanes diet resembl ancient seashor base diet relat aforement diseas adequ iodin might milligram rang toxic low selenium optim selenoprotein p g seleniumday agre japanes intak selenium upper limit may remain gday seafood combin iodin selenium critic nutrient bring us back seashor diet made us current still | D050031;D007455;D012643;D013964 | T047;T121;T191;T123;T196 |
36,235,538 | impact food nutrient dietari pattern telomer length childhood adolesc systemat review environment factor diet affect telomer length tl dynam howev role children adolesc diet play maintain tl well understood thus conduct systemat review examin associ intak nutrient food food group andor dietari pattern tl childhood adolesc follow prisma guidelin search medlin via pubm embas cochran databas addit regist method five select studi cross section conduct children adolesc age year main result suggest higher consumpt fish nut seed fruit veget green leafi crucifer veget oliv legum polyunsatur fatti acid antioxid rich diet might posit affect tl contrari higher intak dairi product simpl sugar sugar sweeten beverag cereal especi white bread diet high glycaem load factor associ tl shorten knowledg first systemat review examin impact dietari intak factor tl childhood adolesc although limit result consist previous studi differ adult popul research need ascertain potenti nutrit determin tl childhood adolesc | D000975;D004032 | T121;T123;T168;T044;T039 |
36,235,537 | situat father strengthen interdisciplinari collabor sociolog histori emerg pohad paradigm background albeit main focus remain larg mother recent year development origin health diseas dohad scientist includ epigeneticist start examin father environ affect diseas risk children argu attent need given father health relat behavior influenc offspr preconcept ie sperm health well patern lifestyl influenc first day research usher new patern origin health diseas pohad paradigm consid welcom equal overemphasi matern influenc epigeneticist excit possibl pohad paradigm also cautious interpret data avoid bias impress socio biolog realiti method review sociolog histor literatur intersect gender food diet across differ social histor context enrich understand father result sociolog histor research famili food practic diet show father abstract vacuum differ class racial exist social stratifi situat choic may constrain unavail confirm epigeneticist research pohad need cautious interpret patern matern dietari influenc offspr health conclus suggest interdisciplinari approach new paradigm draw sociolog histori public health help provid social histor context interpret critic understand patern lifestyl influenc offspr health | D005220;D012661 | T099;T031 |
36,235,536 | protein supplement maxim adapt low volum high intens interv train sedentari healthi adult placebo control doubl blind random studi ampl evid specif nutrit strategi enhanc adapt resist endur train howev still unclear whether post session protein supplement may increas effect low volum high intens interv train low hiit examin impact low hiit combin protein vs placebo supplement cardiometabol health indic sedentari healthi individu forti seven particip yrs perform cycl ergomet low hiit x min maximum heart rate eight week random receiv doubl blind g whey protein pro hiit n isocalor placebo maltodextrin pla hiit n session maximum oxygen uptak vo max primari outcom sever secondari cardiometabol outcom determin pre post intervent vo max increas pro hiit mlkgmin p pla hiit mlkgmin p lt systol diastol blood pressur decreas pro hiit mmhg p lt pla hiit mmhg p lt gamma glutamyl transferas ul p decreas pro hiit alanin aminotransferas ul p pla hiit signific group differ outcom chang conclus low hiit improv vo max cardiometabol marker irrespect supplement condit post session protein supplement seem provid addit benefit low hiit improv cardiometabol health sedentari healthi individu | D002318;D000072696 | T056;T047;T061 |
36,235,535 | repli kuo et al comment du et al gender differ relationship perceiv stress eat behavior sleep dietari risk bodi mass index nutrient thank kuo et al comment | D005247;D000078622 | T055;T168;T040 |
36,235,534 | comment du et al gender differ relationship perceiv stress eat behavior sleep dietari risk bodi mass index nutrient read du et al | D005247;D012890 | T055;T040;T033 |
36,235,309 | review bioactiv compound antioxid activ properti piper speci antioxid compound abl inhibit negat effect come free radic phenomenon imbalanc antioxid product accumul free radic cell tissu caus oxid stress excess free radic enter bodi ward endogen antioxid compound requir antioxid compound come outsid help perform endogen antioxid antioxid come outsid consist synthet natur antioxid howev synthet antioxid option toxic carcinogen effect therefor use natur ingredi altern method need creat new natur antioxid compound piper speci consid possibl medicin plant develop new sourc antioxid sever studi carri start extract level fraction compound piper speci show good antioxid activ current plant use ingredi tradit medicin treat allergi toothach cough review examin distribut botan data pharmacolog especi antioxid activ compound contain five piper speci name piper amalago l piper betl l piper hispidum sw piper longum l piper umbellatum l | D031701;D031721;D010946 | T002 |
36,235,308 | enter glia modul endocannabinoid system new target cannabinoid base nutraceut enter nervous system en part autonom nervous system intrins innerv gastrointestin gi tract wherea enter neuron deepli studi enter glial cell egc receiv less attent howev immun compet cell contribut mainten gi tract homeostasi support epitheli integr provid neuroprotect influenc gi motor function sensat endogen cannabinoid system ec includ endogen classic cannabinoid anandamid arachidonoylglycerol cannabinoid like ligand oleoylethanolamid oea palmitoylethanolamid pea enzym involv metabol faah magl cox classic cb cb non classic trpv gpr ppar receptor ec particip mani process crucial proper function gi tract egc involv thus modul egc ec might benefici treat dysfunct gi tract review explor role egc ec gi tract function dysfunct current knowledg egc may modul ec compon possibl new target cannabinoid cannabinoid like molecul particular potenti nutraceut use | D002186;D063388 | T121;T109;T123 |
36,235,307 | fabric orang fluoresc boron dope graphen quantum dot al ion detect aluminum kind metal often encount also absorb human bodi invis affect bodi certain extent eg caus symptom associ alzheim diseas therefor detect aluminum particular import method detect metal ion includ precipit method electrochem method cumbersom cost fluoresc detect fast sensit method low cost non toxic tradit fluoresc nanomateri high cost high toxic caus harm human bodi graphen quantum dot new type fluoresc nanomateri low cost non toxic compens defect tradit fluoresc nanomateri paper c gqds gqds good perform prepar bottom hydrotherm method use phenylenediamin precursor citric acid boric acid modul good optic properti gqds exhibit orang fluoresc uv irradi c gqds exhibit cyan fluoresc differ metal ion use ion detect found al good quench effect fluoresc gqds reason phenomenon may relat strong bind al ion n function group gqds rapid chelat kinet chelat process separ gqds photoexcit electron hole pair lead rapid electron transfer al turn lead occurr fluoresc quench phenomenon addit good linear relationship concentr al ion fluoresc intens correl coeffici linear regress equat illustr potenti wide applic gqds sens system also demonstr al sensor use detect al ion | D006108;D045663 | T109;T196;T073 |
36,235,306 | luminesc carbon dot wet oliv pomac structur insight photophys properti cytotox carbon nanomateri endow signific luminesc synthes first time abund high local wast wet pomac wp semi solid product industri oliv oil product synthet effort undertaken outshin photoluminesc pl carbon nanoparticl systemat search best reaction condit convert wast biomass main consist holocellulos lignin protein carbon dot cds hydrotherm carbon process blue emit cds high fluoresc quantum yield obtain use comprehens set spectroscop tool ftir raman xps h c nmr combin steadi state time resolv fluoresc spectroscopi ration depict wp cds structur pl properti reach wp cds show convers pl capabl neglig cytotox two mammalian cell line l hela properti excel indic prospect applic biolog imag biosens dynam therapi driven light | D031658;D045663 | T168;T073;T002 |
36,235,305 | synthesi character novel hydrazon deriv isonicotin hydrazid evalu antibacteri cytotox potenti hydrazon activ compound azomethin nhnch group wide studi owe eas prepar divers pharmacolog benefit novel isonicotin hydrazon deriv vanillin aldehyd salicyl aldehyd synthes azomethin linkag character uv visibl ftir ei ms h nmr c nmr spectroscopi compound screen antibacteri activ staphylococcus aureus bacillus subtilus escherichia coli use disc diffus minimum inhibitori concentr mic method cytotox brine shrimp lethal test perform calcul lethal concentr lc result demonstr appreci antibacteri activ appli strain amongst compound code nh nh show maximum inhibit mic respons term cytotox activ maximum effect observ compound nh nh treatment minimum surviv percentag respect hydrazon could potenti candid antitumorigen therapi various human cancer cell | D000970;D006835 | T121;T109 |
36,235,304 | thiazolidin dion scaffold insight recent advanc antimicrobi antioxid hypoglycem agent heterocycl compound contain nitrogen sulfur especi thiazol famili generat special interest term synthet chemistri attribut ubiquit exist pharmacolog dynam natur product also overwhelm power agrochem pharmaceut thiazolidin dion tzd moieti play central role biolog function sever essenti molecul avail substitut third fifth posit thiazolidin dion tzd scaffold make high util versatil moieti exhibit wide rang biolog activ tzd analogu exhibit hypoglycem activ improv insulin resist ppar receptor activ antimicrobi action inhibit cytoplasm mur ligas antioxid action scaveng reactiv oxygen speci ros manuscript effort made review research tzd deriv potenti antimicrobi antioxid antihyperglycem agent period present date along molecular mechan inform patent grant tzd analogu | D000890;D001688;D006571;D045162 | T121;T109;T123 |
36,235,302 | promot efficaci environment safeti pesticid synergist via non ionic gemini surfact short fluorocarbon chain improv util rate pesticid key achiev reduct synerg ad appropri surfact pesticid prepar effect way improv pesticid util fluorin surfact excel surfac activ thermal chemic stabil long chain linear perfluoroalkyl deriv high toxic obvious persist high bioaccumul environ therefor new strategi design fluorin surfact combin excel surfac activ environment safeti would use studi four non ionic gemini surfact short fluorocarbon chain synthes surfac activ result surfact assess basi equilibrium surfac tension dynam surfac tension contact angl compar monomer counterpart gemini surfact mark lower critic micell concentr higher diffus well better wet abil select singl chain surfact gemini surfact good surfac activ synergist glyphos water agent surfact clear improv efficaci herbicid gemini surfact signific greater effect singl chain surfact acut toxic test indic gemini surfact show slight toxic rat | D005466;D006540 | T109;T131 |
36,235,301 | synthes new multisubstitut acyloxyindol compound synthes novel acyloxyindol compound investig reaction pathway present nitro ketoest substrat obtain two step synthet process underw reduct intramolecular addit nucleophil addit acyl afford acyloxyindol one pot base systemat studi establish optim reaction condit focus final acyl step intermedi hydroxyindol optim condit succeed synthes exampl new acyloxyindol deriv modest yield among acyloxyindol compound acetoxyindol compound x general unstabl yield relat lower acyloxyindol expect bulkier alkyl aromat group r could stabil acyloxyindol compound signific one pot reaction four step sequenc success generat compound new might difficult synthes otherwis | D015394 | T085 |
36,235,300 | explor tetradecanoylimino aryl methyl thiazolin deriv alkalin phosphatas inhibitor biochem evalu comput analysi current studi focus laboratori approach conjunct comput method synthesi bioactiv assess uniqu tetradecanoylimino aryl methyl thiazolin k process includ cycliz aroyl arylthiourea propan one presenc trimethylamin bromin use spectroscop techniqu element analys structur elucid assess electron properti densiti function theori dft calcul made bind interact synthes deriv studi molecular dock tool promis result found evalu bioactiv synthes compound alkalin phosphatas drug likeli score indic use chemic entiti pose drug within accept limit data suggest deriv potent inhibitor alkalin phosphatas turn may act lead molecul synthes deriv desir pharmacolog profil treatment specif diseas associ abnorm level alp | D000469;D001966 | T131;T126;T116;T196 |
36,235,299 | layer layer self assembl coat multi function fabric scientometr analysi citespac surfac engin coat increas appli function fabric due eas deposit coat effect endow fabric abund properti among surfac modif method layer layer lbl self assembl emerg import approach creat multifunct surfac fabric review bibliometr analysi visual analysi lbl self assembl coat fabric perform public extract web scienc wos base citespac softwar analysi result show research lbl self assembl coat fabric attract much attent techniqu plenti flexibl applic moreov research lbl self assembl method field function fabric summar includ flame retard fabric antibacteri fabric ultraviolet resist fabric hydrophob fabric electromagnet shield fabric found function fabric chang singular diversif base review sever futur research direct propos weather comfort cost environment friendli consid multifunct coat design | D005411 | T120 |
36,235,298 | dammaran type triterpenoid stem bark aglaia elliptica meliacea cytotox activ two new dammaran type triterpenoid fatti acid ester deriv oleat hydroxydammar en oleat epoxi hydroxydammaran known dammaran type triterpenoid compound hydroxydammar en isol stem bark aglaia elliptica cdc blume chemic structur determin spectroscop method includ ftir nmr one two dimension hresitof ms analysi well chemic derivat comparison previous literatur furthermor synthet analog result transesterif also obtain dihydroxi dammar en epoxi dihydroxydammaran respect cytotox effect isol synthet analog compound evalu use prestoblu reagent mcf breast cancer cell b f melanoma cell line hydroxydammar en show strongest activ mcf breast cancer b f melanoma cell indic keton group c play essenti role cytotox dammaran type triterpenoid hand compound weak cytotox activ two cell line indic presenc fatti acid signific decreas cytotox activ show signific discoveri investig essenti structur featur dammaran type triterpenoid specif futur develop anticanc drug | D031602;D000970;D001943;D008545;D029582;D014315 | T121;T109;T002;T191 |
36,235,297 | uranium isotop u remov water biochar fiber adsorpt studi sub picomolar concentr rang adsorpt u radionuclid biochar fiber sub picomolar concentr rang investig laboratori aqueous solut seawat sampl adsorpt effici k valu relat remov untreat oxid biochar sampl toward u investig function ph adsorb mass ionic strength temperatur mean batch type experi accord experiment data solut ph determin larg degre adsorpt effici adsorb mass surfac oxid lead signific higher k valu ionic strength temperatur effect indic adsorpt base format inner sphere complex endotherm entropi driven process h gt respect regard sorption kinet diffus u solut biochar surfac seem rate determin step applic biochar base adsorb treat radioact u contamin water reveal materi effect adsorb even sub picomolar concentr rang | D014501;D014874;D018508 | T131;T057;T196;T052 |
36,235,295 | molecular analysi melanogenesi inhibitori effect saponin rich fraction argania spinosa leav extract plant saponin abund divers natur product great potenti use drug discoveri research evalu extract saponin rich fraction argan leav argan oil extract byproduct shell pulp press cake effect melanogenesi result show among sampl test saponin rich fraction leav al inhibit melanin product b murin melanoma b cell mechan melanogenesi inhibit elucid determin protein mrna express melanogenesi associ enzym tyrosinas tyr tyrosinas relat protein trp dopachrom tautomeras dct microphthalmia associ transcript factor mitf perform dna microarray analysi result show gml al signific inhibit melanogenesi b cell human epiderm melanocyt respect without cytotox effect al melanogenesi attribut decreas tyr trp mitf express protein mrna level mitf inhibit natur led downregul express tyr trp gene result dna microarray analysi reveal effect melanogenesi associ camp wnt signal pathway gene result studi suggest al may use cosmeceut prepar hyperpigment treatment | D000690;D000068937;D008546;D012503;D029632 | T050;T047;T073;T002;T191;T109 |
36,235,294 | simultan quantif opioid blood urin gas chromatographi mass spectromet modifi dispers solid phase extract techniqu common methodolog liquid liquid extract solid phase extract appli extract opioid biolog specimen ie blood urin techniqu includ lc mslc msms gc ms etc use qualit quantit determin opioid goal present work design green econom rug simpl extract techniqu famous opioid human blood urin simultan quantif gc ms equip inert plus electron impact ei ionize sourc sim mode produc reproduc effici result morphin codein acetylmorphin nalbuphin tramadol dextromethorphan select target opioid anhydr epsom salt appli dspe opioid blood urin acetonitril extract solvent addit sodium phosphat buffer ph n hexan ad remov non polar interf speci sampl bstfa use derivat agent gc ms follow method valid lodlloq uloq determin morphin codein nal buphin tramadol dextromethorphan ngml ngml respect lodlloq uloq determin acetylmorphin ngml ngml respect method appli real blood urin sampl opioid abus result found reproduc true quantif | D009266;D014147 | T121;T109 |
36,235,293 | exploratori qualiti control studi polygonum multiflorum thunb use dinuclear anthraquinon potenti hepatotox recent year hepatotox polygoni multiflora radix pmr attract increas research interest studi suggest anthraquinon may main hepatotox compon relev studi focus mononuclear anthraquinon compon rather binuclear anthraquinon hepatotox dinuclear anthraquinon dianthron investig cell base model next method determin six free total dianthonon pmr pmr praeparata pmrp establish use ultra high perform liquid chromatographi tripl quadrupol mass spectrometri uplc qqq msms use analyz collect sampl data show four binuclear anthraquinon compound hepatotox may potenti toxic indic safeti evalu pmr pmrp herein provid theoret basi improv pmrp qualiti standard | D056486;D004365;D000068676;D028502 | T047;T002;T037;T121;T123 |
36,235,292 | aspergillus ochraceus metabolit bioactiv biosynthesi biotechnolog potenti fungus continu attract great attent promis pool biometabolit aspergillus ochraceus wilh aspergillacea establish capac biosynthes myriad metabolit belong differ chemic class isocoumarin pyrazin sterol indol alkaloid diketopiperazin polyketid peptid quinon polyketid sesquiterpenoid reveal various bioactiv antimicrobi cytotox antivir anti inflammatori insecticid neuroprotect addit ochraceus produc varieti enzym could variabl industri biotechnolog applic june metabolit report ochraceus isol differ sourc review former separ metabolit ochraceus includ bioactiv biosynthesi addit industri biotechnolog potenti ochraceus highlight | D000890;D061065 | T121;T109 |
36,235,291 | synthesi sar analysi novel hydroxytamoxifen analogu base cytotox activ electron donor charact util mcmurri reaction dihydroxybenzophenon appropri carbonyl compound seri hydroxytamoxifen analogu synthes cytotox activ evalu vitro four human malign cell line mcf mda mb ht found novel tamoxifen analogu show mark cytotox dose depend manner relat ros generat capabl synthet analogu evalu cyclic voltammetri cv dft model studi result cell viabil assay cv measur dft calcul suggest cytotox major novel compound main elicit interact cellular target includ estrogen receptor rather trigger redox process howev three novel compound could involv ros product subsequ format quinon methid prevent prolifer disrupt redox balanc treat cell among cell line studi ht prove suscept treatment compound ros generat potenc | D000970;D001943 | T121;T109;T191 |
36,235,289 | high sensit robust recycl tio agnp substrat ser detect label free biosensor provid import platform detect chemic biolog substanc without need extra label agent unlik surfac base techniqu surfac plasmon reson spr interfer ellipsometri surfac enhanc raman spectroscopi ser possess advantag monitor analyt surfac solut increas ser enhanc crucial prepar high qualiti substrat without quick lose stabil sensit repeat howev fabric method base wet chemistri nanoimprint lithographi spark discharg laser ablat drawback wast time complic process nonreproduc surfac topographi studi report prepar recycl tio ag nanoparticl agnp substrat use simpl arc ion plate direct current dc magnetron sputter technolog deposit anatas phase tio ensur photocatalyt degrad analyt measur raman spectra rhodamin g rg titrat concentr limit detect lod ser enhanc factor ef attain self clean perform via uv irradi recycl achiev least five cycl detect degrad propos tio agnp substrat potenti serv eco friend ser enhanc label free detect various chemic biolog substanc | D053768;D012834 | T196;T073 |
36,235,288 | develop stabl liposom drug deliveri system thymoquinon vitro anticanc studi use breast cancer cervic cancer cell line thymoquinon well known phytoconstitu deriv seed nigella sativa exhibit uniqu pharmacolog activ howev despit various medicin properti thymoquinon administr vivo remain challeng due poor aqueous solubl bioavail stabil therefor advanc drugdeliveri system requir improv therapeut outcom thymoquinon enhanc solubl stabil biolog system therefor studi main focus prepar thymoquinon load liposom improv physicochem stabil gastric media perform differ cancer cell line studi liposom prepar use phospholipid extract egg yolk liposom nano prepar evalu term hydrodynam diamet zeta potenti microscop analysi entrap effici cell viabil measur conduct use breast cervic cancer cell line optim liposom prepar exhibit polygon globul like shape hydrodynam diamet less nm pdi zeta potenti valu mv solid state character perform use dsc xrpd show freez dri liposom prepar amorph natur gastric ph stabil data show physic chang precipit degrad signific growth averag size blank thymoquinon load liposom h cell line studi exhibit better perform thymoquinon load liposom drug deliveri system compar thymoquinon solut find play critic role improv breast cervic cancer treatment manag | D001943;D002583 | T191 |
36,235,287 | determin residu diisocyan relat diamin biodegrad mulch film use n ethoxycarbonyl derivat gc ms diisocyan high reactiv compound two function isocyan group exposur diisocyan associ sever advers health effect asthma inflamm respiratori tract cancer hydrolysi product diisocyan relat diamin also potenti carcinogen develop effect accur precis method simultan determin residu diisocyan relat diamin biodegrad mulch film base n ethoxycarbonyl derivat gas chromatographi mass spectrometri method develop includ optim ultrason hydrolysi extract screen n ethoxycarbonyl condit ethyl chloroform evalu diamin degrad analysi fragment mechan optimum experiment condit good linear observ r gt extract recoveri found rang repeat reproduc respect limit detect rang gml develop method appli commerci polybutylen adip co terephthal pbat biodegrad mulch film sampl analysi divers residu diisocyan relat diamin addit compon vari great among sampl differ origin overal studi provid reliabl method assess safeti biodegrad mulch film | D003959;D017953 | T109 |
36,235,286 | investig antifung photocatalyt physicochem properti sol gel produc tin dioxid nanoparticl transmiss electron microscopi tem atom forc microscopi afm x ray diffract xrd energi dispers x ray edx scan electron microscopi sem diffus reflect spectroscopi drs fourier transform infrar ftir spectroscopi appli evalu tin dioxid nanoparticl sno nps amalgam sol gel process xrd use examin tetragon shape crystallit averag size nm wherea averag particl size estim tem micrograph nm dose depend antifun activ perform two fungal speci activ observ increas increas concentr sno nps photocatalyt activ sno nps aqueous media test use rhodamin g rh g solar light illumin rh g degrad rate min total percent min | D000935;D053758 | T121;T073;T195 |
36,235,285 | effect laser induc optic breakdown structur bsa molecul aqueous solut optic studi influenc laser radiat typic surgic laser physicochem properti bovin serum albumin bsa protein studi establish physicochem characterist optic breakdown weak depend concentr protein molecul time pattern observ aqueous solut bsa irradi laser differ time period extrem similar classic one establish exposur laser radiat optic densiti protein solut increas time intens bsa fluoresc due aromat amino acid residu decreas insignific exposur laser radiat case posit excit emiss maximum chang shape fluoresc spot map also chang signific raman spectrum exposur laser radiat signific decreas cm observ indic degrad helic result partial denatur bsa molecul partial denatur signific chang total area protein molecul sinc refract index solut chang signific howev bsa solut exposur laser radiat viscos increas pseudoplast aqueous solut decreas case massiv damag polypeptid chain contrari expos optic breakdown intens aggreg observ aggreg size nm appear solut thus action optic breakdown induc laser radiat bsa solut process partial denatur aggreg prevail aromat amino acid residu damag lesser extent fragment protein molecul observ | D012710;D014867 | T116;T121;T123;T130;T197 |
36,235,284 | conform essenti respons neurotox aggreg reveal antibodi oligomer solubl aggreg amyloid peptid deposit aggreg initi patholog hallmark alzheim diseas ad bipolar natur molecul result abil assembl distinct oligom higher aggreg may drive phenotyp heterogen observ ad agent target aggreg anti antibodi inhibit aggreg toxic aggreg neural cell certain extent howev epitop specif antibodi affect bind affin differ speci differ antibodi target differ site thus elicit differ neuroprotect cytoprotect effect present review summar signific inform reflect anti antibodi differ immunotherapi propos overview structur conform toxic relationship aggreg review aim provid refer direct design antibodi pathogen conform aggreg | D000544;D020258 | T047;T037;T048 |
36,235,283 | sensit select reliabl detect fe lake water via carbon dot base fluoresc assay studi c dot facil synthes via microwav irradi use citric acid ethylenediamin carbon precursor fluoresc emiss c dot could select quench fe degre quench linear relat concentr fe present phenomenon util develop sensit fluoresc assay fe detect broad linear rang moll low detect limit moll import assay demonstr high reliabl toward sampl deioniz water tap water lake water find potenti applic fe monitor complic environ | D002244;D045663 | T121;T196;T073 |
36,235,281 | dextran fluoresc probe contain sulfadiazin rhodamin b group fluoresc imag expand non invas diagnost modal cancer recent year fluoresc probe near infrar window provid high sensit resolut signal nois ratio without use ioniz radiat fluoresc compound low molecular weight rhodamin b rhb indocyanin green icg use fluoresc imag improv imag contrast sensit howev sinc probe excret bodi quick possess signific restrict imag find potenti solut work investig synthesi properti novel macromolecular fluoresc compound herein water solubl dextran fluoresc compound sd dextran rhb prepar attach rhb sulfadiazin sd deriv dextran carrier fluoresc compound character ir h nmr c nmr uv gpc method assay cellular uptak cell cytotox fluoresc imag also perform studi found sd dextran rhb sensit acid condit possess low cell cytotox compar normal cell hepg hela tumor cell moreov sd dextran rhb demonstr good fluoresc imag hepg hela cell therefor sd dextran rhb suitabl potenti appli probe fluoresc imag tumor | D003911;D005456 | T121;T109;T123;T130 |
36,235,280 | revers sorptiv preconcentr nobl metal follow fi icp ms determin paper propos combin procedur nobl metal nm determin includ fire assay acid digest revers dynam sorptiv preconcentr follow flow inject icp ms revers preconcentr nms carri use micro column pack new pvbc vp sorbent elut mixtur thiourea potassium thiocyan hcl recov pd ir pt au ru rh propos procedur approv use certifi refer materi | D008670;D013890 | T109;T130;T197 |
36,235,279 | non convent time domain td nmr approach food qualiti case gelatin base candi model food td nmr techniqu most involv use spin lattic spin spin relax time explain chang occur food system howev relax time affect mani factor might alway best indic work food relat td nmr studi studi non convent td nmr approach solid echo se magic sandwich echo mse spin diffus food system use first time soft confectionari gelatin gel formul convent non convent se mse spin diffus td nmr experi perform corn syrup differ glucosefructos composit use prepar soft candi hard brix bx water activ w measur also conduct complementari nmr experi relax time chang p lt respect syrup type obvious trend sems experi perform calcul crystallin sampl sampl prepar fructos lowest crystallin valu p lt spin diffus experi perform use goldman shen puls sequenc interfac thick calcul interfac thick valu show wide rang variat p lt result show non convent nmr approach high potenti util food system qualiti control purpos | D002182;D005780 | T121;T168;T116 |
36,235,278 | nitrogenas fe protein multi task player substrat reduct metalloclust assembl fe protein nitrogenas play multipl role substrat reduct metalloclust assembl best known function transfer electron catalyt partner nitrogenas catalysi fe protein also key player biosynthesi complex metalloclust nitrogenas addit function reductas affect ambient reduct co co hydrocarbon review provid overview properti function fe protein highlight relev uniqu fes enzym area relat catalysi biosynthesi applic fascin nitrogenas system | D002245;D009591 | T126;T123;T116;T197 |
36,235,277 | theoret studi aggreg adsorpt behavior anticanc drug molecul graphenegraphen oxid surfac graphen deriv frequent use cancer therapi widespread interest improv therapeut effici target drug paper geometr structur electron effect anastrozol ana camptothecin cpt gefitinib gefi resveratrol res graphen graphen oxid go investig densiti function theori dft calcul molecular dynam md simul meanwhil explor compar adsorpt process graphenego four drug molecul well adsorpt site carrier payload addit calcul interact forc four drug molecul graphen believ work contribut deepen understand load behavior anticanc drug onto nanomateri interact | D000970;D006108 | T121;T109;T196 |
36,235,276 | photoprotect effect cannabidiol ultraviolet b induc dna damag autophagi human keratinocyt cell mous skin tissu cannabidiol cbd emerg phytocannabinoid various benefici effect skin includ anti photoag effect mechan action fulli elucid studi assess cbd photoprotect effect acut ultraviolet b uvb induc damag hacat human keratinocyt cell murin skin tissu cbd allevi uvb induc cytotox apoptosi gm cell cycl arrest hacat cell content hax cyclobutan pyrimidin dimer decreas cbd treatment cbd reduc product reactiv oxygen speci modul express antioxid relat protein nuclear factor erythroid relat factor uvb stimul hacat cell furthermor cbd mitig uvb induc cytotox activ autophagi addit cream contain cbd show effect uvb induc photodamag murin model cbd cream improv skin condit lower photodamag score reduc abnorm skin prolifer decreas express inflamm relat protein cyclooxygenas uvb irradi skin tissu find indic cbd might benefici allevi uvb induc skin damag human photoprotect effect cbd might attribut modulatori effect redox homeostasi autophagi | D002185 | T121;T109 |
36,235,275 | steroid resist associ high mif p gp serum level sle patient approxim patient system lupus erythematosus sle present steroid resist sr macrophag migrat inhibit factor mif p glycoprotein p gp could relat sr work aim evalu relationship mif p pg serum level sr sle | D008180;D008263 | T047;T123;T116;T129 |
36,235,274 | toward hydrophob thermoplast starch use fatti acid starch ester addit bring surfac hydrophob thermoplast starch tps materi food packag fatti acid starch ester fase specif starch tri laurat incorpor tps formul total three differ ratio fase ad tps formul evalu influenc fase onto physico chemic properti tpsfase blend ie surfac hydrophob dynam vapor sorption dvs tensil behavior blend tps fase lead hydrophob materi whatev fase ratio initi measur contact angl rang fase blend blend ft ir studi materi surfac inner core show fase main locat materi surfac justifi increas materi surfac hydrophob despit surfac hydrophob blend tps fase seem affect blend vapor sorption behavior mechan behavior perspect variabl tensil properti starch base materi humid rate slight reduc increas fase ratio decreas maxim stress observ fase ratio lead ductil materi | D007848;D013213 | T121;T109;T123;T168 |
36,235,273 | cellulos nanofib schinus moll prepar character schinus moll sm investig primari sourc cellulos aim discov resourc generat cellulos nanofib cnf sm put soda pulp process purifi cellulos fiber treat enzymat treatment twin screw extrud andor masuko util help fiber delamin nanofibril process enzymat treatment twin screw extrud masuko treatment give yield respect optic atom forc microscopi morfi polymer degre prepar cellulos materi establish pulp fiber collect follow treatment stage demonstr fiber characterist length crystallin vari accord use treatment mechan enzymat treatment obvious enzym treatment result shorter fiber increas degre polymer howev cnf obtain enzymat extrus treatment achiev gave nm arithmet width young modulus gpa | D027926;D057139 | T073;T002 |
36,235,272 | antiglyc effect adlay seed activ polyphenol compound vitro studi studi aim evalu antiglyc effect adlay protein glycat use vitro glycat assay adlay seed divid follow four part hull ah testa bran ab polish adlay pa solvent extract techniqu column chromatographi util investig activ fraction compon adlay base bsa glucos assay ethanol extract ate ab abe reveal greater capac inhibit protein glycat ate consecut partit four solvent fraction n hexan ethyl acet ate ea butanol ate buoh water ate buoh ea show mark inhibit glucos mediat glycat medium high polar subfract elut ate buoh methanol diaion hp ate buoh c f exhibit superior antiglyc activ maximum inhibitori percentag two phenol compound chlorogen acid ferul acid identifi ate buoh hplc exhibit potent inhibit individu stage protein glycat subsequ crosslink evalu bsa glucos assay bs methylglyox mgo assay gk peptid ribos assay conclus studi demonstr antiglyc properti ate vitro suggest benefici effect target hyperglycemia mediat protein modif | D031742;D059808 | T121;T109;T002 |
36,235,271 | screen determin synthet pde inhibitor adulter sexual enhanc supplement paper report import investig quantif adulter sexual enhanc supplement prescript medicin avail unit arab emir uae tadalafil sildenafil vardenafil total sexual enhanc supplement collect analyz current studi sampl screen use revers phase liquid chromatographi tandem high resolut mass spectrometrymass spectrometri rp hplc msms sexual enhanc ci contain undeclar sildenafil ci contain undeclar tadalafil ci contain undeclar vardenafil sexual enhanc supplement ci contain signific concentr sildenafil tadalafil vardenafil studi found relat low level undeclar pharmaceut ingredi sexual enhanc dietari supplement avail uae market like patient ed tend consum multipl supplement daili therebi expos high elev cumul level | D058986;D053719 | T121;T063 |
36,235,270 | emerg effect resveratrol wound heal comprehens review resveratrol rsv natur extract extens studi signific anti inflammatori antioxid effect close associ varieti injuri diseas even cosmet medicin review research summar role resveratrol differ form action wound heal explor role mechan promot wound heal differ mode action hydrogel fibrous scaffold parallel ratio medic devic anti inflammatori antioxid antibacteri anti age properti function various cell may play role wound heal provid direct understand mechan action resveratrol wound heal futur research | D000975;D014945 | T121;T123;T040;T044;T039 |
36,235,269 | hierarch annular mesopor carbon deriv phenol resin effici remov antibiot wastewat antibiot becom new type environment pollut due extens use high perform adsorb paramount signific cost effect environment friend strategi remov antibiot water environ herein report novel annular mesopor carbon mcn prepar phenol resin triblock copolym f high perform adsorb remov penicillin streptomycin tetracyclin hydrochlorid wastewat mcns high puriti rich annular mesoporos high surfac area g larg pore volum cm g improv adsorpt capac facilit effici remov penicillin streptomycin tetracyclin hydrochlorid water applic mcns treat three kind residu antibiot adsorpt amount tetracyclin hydrochlorid higher penicillin streptomycin adsorpt capac mgg moreov high remov effici excel recycl achiev result demonstr mcn adsorb signific potenti treatment water contamin antibiot | D062065;D014874 | T069;T131;T083 |
36,235,268 | autotox endogen organ acid stress two ganoderma lucidum cultivar ganoderma lucidum use rare medic mushroom centuri china due health promot properti success crop obstacl common cultiv g lucidum although remain nutrient germ substrat suffici second fruit aim studi metabolit profil g lucidum amp nbsp via nontarget metabonom technolog metabonom data reveal organ acid play import role crop obstacl g lucidum accord ph decreas germ substrat kyoto encyclopedia gene genom kegg enrich analysi indic differenti acid particip metabol pathway five acid signific upregul two ms high energi ms e mode two cultivar among hydroxi oxo ureido dihydro h imidazol carboxyl acid also involv purin metabol regul microbi metabol divers environ taken togeth work illustr organ acid stress generat g lucidum form autotox feedback result crop obstacl determin caus crop obstacl g lucidum promot util rate fungus substrat realiz sustain use resourc | D032902;D020940 | T004 |
36,235,267 | paramet optim support vector machin improv predict perform determin aflatoxin b peanut olfactori visual techniqu studi propos novel method detect aflatoxin b afb peanut use olfactori visual techniqu first kind chemic dye select prepar colorimetr sensor assembl olfactori visual system use collect odor characterist inform peanut sampl genet algorithm ga back propag neural network bpnn regressor use optim color compon preprocess sensor featur imag support vector regress svr quantit analysi model construct use optim combin characterist color compon achiev determin afb peanut process optim perform grid search gs algorithm sparrow search algorithm ssa svr paramet compar compar gs svr model model perform ssa svr better result show ssa svr model combin seven characterist color compon obtain best predict effect correl coeffici predict r p reach root mean squar error predict rmsep gkg ratio perform deviat rpd valu result indic reliabl use colorimetr sensor array strong specif determin afb peanut addit necessari proper optim paramet predict model obvious improv general perform multivari model | D016604;D060388 | T066;T131;T081;T109;T196 |
36,235,266 | erdafitinib inhibit tumorigenesi human lung adenocarcinoma induc phase cell cycl arrest cdk inhibitor lung adenocarcinoma ladc preval lung cancer sub type target therapi develop recent year made progress treatment erdafitinib potent select pan fgfr tyrosin kinas inhibitor confirm effect treatment ladc howev molecular mechan respons effect unclear vitro studi show erdafitinib exhibit outstand anti cancer activ human ladc cell line induc phase cell cycl arrest cell apoptosi mechanist studi base transcriptom data reveal erdafitinib exert anti cancer effect affect cell cycl relat pathway cdk regulatori target drug addit cdk overexpress signific attenu anti cancer effect erdafitinib affect transcript activ express ef well express cdk vivo studi show erdafitinib present obvious anti cancer effect xenograft mice model accompani reduc express cdk thus studi demonstr anti cancer effect erdafitinib ladc first time base vitro vivo model whose activ achiev target cdk regul downstream ef cdk signal studi may help expand clinic applic erdafitinib treat ladc | D000077192;D008175 | T191 |
36,235,265 | ultrathin coval organ framework nanosheetsti c x base photoelectrochem biosensor effici detect prostat specif antigen design ultrathin coval organ framework nanosheet con good photoelectr activ promis candid construct photoelectrochem pec biosensor detect low abund biolog substrat howev achiev high sensit pec properti use emerg coval organ framework nanosheet con remain great challeng due polymer natur poor photoelectr activ con herein report first time prepar novel composit pec sens properti electrostat self assembl ultrathin con call ttpa con ti c x prepar ttpa consti c x composit use photocathod pec detect prostat specif antigen psa high sensit low detect limit good stabil work expand applic con also open new avenu develop effici pec sens platform | D015374;D000073396 | T059;T075;T109 |
36,235,264 | oxid product curcumin rather curcumin bind helicobact pylori virul factor vaca requir inhibit vacuol activ curcumin hydrophob polyphenol deriv turmer potent anti oxid anti microbi anti inflammatori anti carcinogen effect curcumin degrad various deriv vitro vivo condit appear degrad may respons pharmacolog effect curcumin primari risk factor caus gastric cancer helicobact pylori h pylori virul factor vacuol cytotox vaca secret h pylori kda monom p fragment kda n termin domain p kda c termin domain p recent report curcumin oxid requir inhibit activ anoth major hpylori toxin caga perform molecular dock curcumin oxid deriv p p domain vaca examin effect oxid curcumin vacuol activ vaca protein observ bind curcumin p domain vaca five differ site moder bind affin curcumin bind p domain vaca remark cyclobutyl cyclopentadion dihydroxi cyclopentadion oxid product curcumin show higher bind affin vaca protein site except one compar parent curcumin howev cyclobutyl cyclopentadion show signific bind affin activ site p protein activ site five p domain vaca play crucial role vaca mediat vacuol format invitro experi show curcumin inhibit vacuol activ h pylori human gastric cell line ag cell wherea acetyl diacetyl curcumin oxid fail inhibit vacuol ag cell h pylori infect data show oxid essenti activ curcumin inhibit vacuol activ h pylori synthesi oxid curcumin deriv could potenti provid new therapeut drug molecul inhibit h pylori mediat pathogenesi | D016588;D000970;D003474;D016481;D016480 | T047;T007;T121;T109;T130;T039 |
36,235,263 | mentha nutrit health attribut treat various ailment includ cardiovascular diseas poor diet result malnutrit critic challeng lead varieti metabol disord includ obes diabet cardiovascular diseas mentha speci famous therapeut herb long serv herbal medicin recent demand product herbal drug medicin natur herbal formul increas signific howev avail literatur lack thorough overview mentha phytochem effect reduc malnutrit risk cardiovascular diseas context aim review recent advanc mentha phytochem futur challeng reduc malnutrit risk cardiovascular patient current studi indic mentha speci phytochem possess uniqu antimicrobi antidiabet cytotox antioxid potenti use herbal medicin direct indirect food ingredi effect control cure cardiovascular diseas presenc aromat flavor compound mentha speci great enhanc nutrit valu food interdisciplinari investig pivot explor main volatil compound synergist action phytochem organolept effect stabil mentha sp phytochem | D000890;D002318;D000074385;D027541;D010946 | T121;T047;T168;T002 |
36,235,261 | prepar character biolog activ oil water nanoemuls fish product lemon oil ultrason method fish product oil lemon oil potenti applic activ ingredi mani industri includ cosmet pharmaceut food howev physicochem properti especi poor stabil compromis usag general nanoemuls use approach stabil oil studi employ ultrason method form oil water nanoemuls lemon fish product oil ne flo formul produc fix amount wt fish product oil wt lemon oil wt surfact wt co surfact min ultrason time size polydispers index pdi zeta potenti obtain nm mv respect biolog properti includ antioxid antibacteri cell cytotox anti inflammatori show outstand perform antioxid activ compar without signific differ ascorb acid standard superior pure lemon oil ne flo success inhibit seven gram posit seven gram negat bacteri strain ne flo anti inflammatori activ compar nordihydroguaiaret acid ndga standard high concentr gml ne flo non toxic normal skin cell find demonstr ne flo produc studi signific potenti usag various industri | D000975;D010938 | T121;T109;T123;T168;T044;T039 |
36,235,260 | develop semisynthet apoptosi induc agent base natur phenol acid scaffold design synthesi vitro biolog evalu crucial target drug research magnifi efficaci decreas toxic therefor use natur activ constitu precursor enhanc safeti biolog activ despit mani pharmacolog activ caffeic ferul acid show limit clinic usag due poor bioavail fast elimin therefor semisynthet compound two acid prepar screen anticanc agent studi ca fa show potent anticanc activ caco cell consequ eighteen deriv test cell line four potent candid select determin select index compound reveal high safeti margin compound repres new scaffold show signific cytotox activ caco cell cycl analysi evalu apoptosi show deriv show highest proport cell late apoptot stage | D000970;D015195 | T121;T090;T109 |
36,235,258 | novel unsymmetr bis benzyliden piperidon display tumor select toxic two seri novel unsymmetr bis benzyliden piperidon f e design candid antineoplast agent compound display potent cytotox toward two colon cancer well sever oral squamous cell carcinoma compound less toxic various non malign cell give rise larg select index si figur mani compound also cytotox toward cem lymphoma hl leukemia cell repres compound induc apoptot cell death character caspas activ subg accumul oscc cell well depolar mitochondri membran potenti cem cell line inquiri direct find si valu correl atom charg olefin carbon atom potenti compound antineoplast agent enhanc adm absorpt distribut metabol excret evalu five lead molecul reveal violat | D000970;D010881 | T121;T109 |
36,235,257 | syring acid amelior cardiac hepat renal neuron damag induc chronic hyperglycaemia wistar rat behaviour biochem histolog analysi studi investig effect syring acid sa renal cardiac hepat neuron diabet complic streptozotocin induc neonat nstz diabet rat stz mgkg ip inject wistar rat neonat split dose second third postnat day diabet mellitus diagnos adult measur fast blood glucos level urin volum food water intak treatment sa mgkg mgkg po given th th postnat week assess develop diabet complic effect therapi biochem indic serum behaviour paramet record specif interv studi period sa mgkg mgkg po treatment reduc hyperglycaemia polydipsia polyphagia polyuria relat organ weight cardiac hypertroph indic inflammatori marker cell injuri marker glycat haemoglobin histopatholog score oxid stress increas nak atpas activ find suggest sa might signific allevi diabet complic andor renal neuron cardiac hepat damag nstz diabet rat | D003921;D006943 | T050;T047;T033 |
36,235,256 | comprehens lichenometabolom explor ramalina conduplican vain use uplc q tof msms identif free radic scaveng anti hyperglycem constitu studi propos ultra perform liquid chromatographi coupl quadrupoletim flight mass spectrometri uplc qtof msms guid metabolit isol choic analyt approach ongo structur activ investig chemic isol edibl lichen ramalina conduplican vain strategi led isol identif new depsid along known compound newli describ lichen speci structur isol establish detail analysi spectral data ir nmr mass aceton extract analyz uplc q tof msms negat ionize mode facilit identif confirm compound base fragment pattern antioxid capac lichen aceton extract ae isol measur track dpph abt free radic scaveng activ isol display mark radic scaveng activ abt moder activ observ dpph radic scaveng except atranol oxid dna damag limit test compound mark protect novel isol compound previous note aceton extract p lt furthermor compound aceton extract ae inhibit intestin glucosidas enzym signific p lt although phytochem studi alreadi perform lichen studi provid new insight isol identif bioactiv compound illustr interest futur novel analyt techniqu | D000975;D053719 | T063;T121;T123;T044;T039 |
36,235,255 | smart extract chain green solvent extract bioactiv compound picea abi bark wast pharmaceut nutraceut cosmet use secondari metabolit sawmil wast picea abi bark extract use innov two step extract includ first step supercrit co sco second step use green solvent name ethanol water water ethanol mixtur macer ultrasound assist extract uae microwav assist extract mae techniqu appli second step total nineteen extract obtain yield compar bark extract character lc dad ms n class compound quantifi abietan deriv piceasid flavonoid phenol compar differ extract obtain extract studi vitro assay evalu potenti pharmaceut nutraceut cosmet use assess antioxid activ well inhibitori activ target enzym result show smart extract chain advantag term yield extract phytoconstitu concentr sco extract present uniqu composit larg amount abietan deriv exert best activ amylas inhibit compar extract | D028202;D028222;D028223 | T002 |
36,235,254 | ava np select inhibit enpp activ sting pathway abrog tumor metastasi breast cancer syngen mous model cyclic gmp amp synthas cgas endogen dna sensor synthes cyclic guanosin monophosph adenosin monophosph cgamp atp gtp cgamp activ stimul interferon gene sting pathway result product interferon pro inflammatori cytokin ectonucleotid pyrophosphatasephosphodiesteras enpp phosphodiesteras negat regul sting pathway hydrolyz cgamp establish cgas sting pathway play major role inhibit tumor growth upregul cell respons herein demonstr ava np select high potent enpp inhibitor apart immunomodulatori effect also modul cancer metastasi negat regul epitheli mesenchym transit emt establish combin addit cgamp ava np signific abrog transform growth factor beta tgf induc emt mda mb cell final result vivo studi show superior tumor growth inhibit impact tumor metastasi ava np compar olaparib pd syngen breast cancer mous model translat efficaci vitro vivo tumor model provid strong rational therapeut potenti ava np tripl negat breast cancer tnbc immunomodulatori anti metastat agent | D061026;D064726 | T191;T192;T116;T129 |
36,235,253 | noncod rnas emerg drug drug target chemic modif bio conjug intracellular regul increas understand various diseas relat noncod rnas ncrnas emerg novel drug drug target nucleic acid drug base differ type noncod rnas design test chemic modif appli noncod rnas sirna mirna increas resist degrad minimum influenc biolog function chemic biolog method also develop regul relev noncod rnas occurr various diseas new strategi design ribonucleas target chimera degrad endogen noncod rnas emerg promis approach regul gene express serv next generat drug review summar current state noncod rna base theranost major chemic modif noncod rnas develop nucleic acid drug conjug rna differ function biomolecul well design screen potenti molecul regul express activ endogen noncod rnas drug develop final strategi improv deliveri noncod rnas discuss | D035683;D022661 | T123;T114 |
36,235,252 | indan base molecular motor uv switch increas number isom describ azophenylindan base molecular motor aphin switch two differ rotam tran configur four differ rotam cis configur behavior motor investig experiment comput convers aphin switch yield singl isom mixtur although tran cis convers lead increas system entropi cis rotam direct convert other convert via tran configur motion aphin switch resembl work mix machin indan group serv base phenol group serv beater aphin switch present herein may provid basi promis applic advanc biolog system particular case demand disord molecular pack valu lipid bilay | D007189;D008051 | T026;T109 |
36,235,251 | evalu major constitu medicin import plant anti inflammatori antidiabet age inhibit properti vitro simulatori evid diabet mellitus dm global health concern associ sever micro macrovascular complic evalu sever import medicin plant constitu includ polyphenol flavonoid glucosidas inhibit age inhibitori activ use oxid oxid assay inhibit protein cross link format lipoxydenas inhibit molecular dock molecular dock studi show high bind energi flavonoid transcript regular ik top fs glucosidas inhibit assay signific inhibit note quercitrin ic gml gallic acid ic gml age inhibit assay quercetin show signific result non oxid ic mgml oxid assay ic mgml furthermor quercitrin show inhibitori activ non oxid ic mgml oxid assay ic mgml signific inhibit protein cross link format observ sds page analysi quercitrin quercetin show signific inhibit lipoxygenas thus conclud flavonoid polyphenol present plant extract effect manag diabet alli co morbid | D003920;D007004 | T121;T047;T039 |
36,235,250 | prepar fucoxanthin nanoemuls stabil natur emulsifi fucoidan sodium casein gum arab studi propos investig possibl ow nanoemuls stabil via natur emulsifi deliveri system fucoxanthin nanoemuls prepar use ultrason treatment w amplitud min differ level wt fucoidan gum arab sodium casein natur emulsifir compar tween cream index stabil encapsul efficaci fourier transform infrar ft ir spectroscopi vitro releas evalu best stabil lowest cream index observ wt emulsifi nanoemuls droplet size nm zeta potenti mv prepar droplet size nanoemuls reduc increas emulsifi concentr best nanoemuls stabil day storag follow order tween gt sodium casein gt fucoidan gt gum arab encapsul efficaci nanoemuls stabil sodium casein fucoidan gum arab respect vitro gastrointestin fucoxanthin releas nanoemuls stabil tween sodium casein fucoidan gum arab respect releas fucoxanthin nanoemuls follow fickian diffus ftir also confirm encapsul fucoxanthin | D002364;D006170 | T121;T109;T123;T116 |
36,235,249 | anti mycobacteri activ flavonoid pyrimidin compound evalu anti mycobacteri effect flavonoid dihydroxi hydroxyphenyl h chromen one two pyrimidin hydroxi dimethylamino nitroso aminopyrimidin chloro n nonylpyrimidin vitro mycobacterium tuberculosi tuberculosi hra mycobacterium avium avium use micropl alamar blue assay maba effect compound combin first second line anti tb drug isoniazid rifampicin cycloserin clarithromycin growth tuberculosi avium also evalu vitro assay singl agent compound exhibit modest activ compound effect tuberculosi avium compound evalu lower inhibitori concentr two drug combin isoniazid rifampicin show addit synergist interact inhibitori effect improv three compound test togeth three drug combin two first line anti tb drug compound also demonstr strong synergist interact combin cycloserin clarithromycin inhibit growth tuberculosi avium respect studi demonstr compound potenti develop effect anti tb agent combin use | D009169;D014376 | T007;T047 |
36,235,248 | comparison odor beef chicken broth focus thiazol thiazolin shift consum landscap toward vegan vegetarian flexitarian diet creat unpreced challeng creat meat aroma plant base altern search potenti vegan solut thus led renew interest authent meat flavour profil gain better understand qualit odour differ boil beef boil chicken aroma extract isol use liken nickerson simultan distil extract sde select expressli situ heat sampl facilit captur aroma intermedi cook process therebi mimick cook meat stock stew extract analys gas chromatographi mass spectrometri gc ms gc olfactometri gc volatil identifi studi sulfur contain compound sulfid thiol mercaptoaldehyd mercaptoketon deriv maillard reaction meanwhil lipid oxid result format unsatur aldehyd alken alkadien famili thiazol thiazolin found extract two novel thiazolin ethyl dimethyl thiazolin ethyl dimethyl thiazolin may also contribut meati aroma identifi work synthesis respect aldehyd mercaptoketon precursor | D009812;D055549 | T109;T120;T070 |
36,235,247 | design synthesi coumarin deriv cytotox agent pikakt signal pathway inhibit hl hepg cancer cell studi seri coumarin deriv either alon hybrid cinnam acid synthes evalu cytotox panel cancer cell use mtt assay activ compound inspect mechan cytotox cell cycl analysi rt pcr dna fragment western blot techniqu cytotox result show compound signific cytotox effect hl cell ic compound b notic activ hepg cell ic compound b mediat cytotox via pikakt pathway inhibit result assur molecular dock studi result support exploratori research focus therapeut activ coumarin deriv cytotox agent | D000970;D009369 | T121;T109;T191 |
36,235,246 | comput insight carbolin inhibit monoamin oxidas monoamin oxidas mao import group enzym involv degrad neurotransmitt imbalanc mode action may lead develop various neuropsychiatr neurodegen disord work report result depth comput studi perform static dynam analysi seri substitut carbolin natur product found main roast coffe tobacco smoke bind activ site mao isoform appli molecular dock conjunct structur base pharmacophor molecular dynam simul coupl dynam pharmacophor extens investig geometr aspect mao bind gain insight energet bind use linear interact energi lie method determin key anchor allow product carbolin bind mao result present herein could appli ration structur base design optim carbolin toward preclin candid would target mao enzym would applic especi treatment mental disord depress | D008996;D014028 | T121;T069;T109;T033 |
36,235,245 | diaza butadien use intermedi heterocycl synthesi mani heterocycl compound synthet use diaza butadien dad key structur precursor isol situ diaza butadien produc respect precursor typic imin hydrazon varieti condit react wide rang substrat mani kind reaction reaction discuss includ nucleophil addit michael type reaction cycloaddit diel alder invers electron demand diel alder aza diel alder reaction review focus report last year employ diaza diaza diaza diaza butadien intermedi synthes heterocycl indol pyrazol triazol imidazolin pyrimidinon pyrazolin lactam imidazolidin among other fuse heterocycl quinazolin isoquinolin dihydroquinoxalin deriv also includ review | D048289;D048288 | T109 |
36,235,244 | discoveri small alloster activ site inhibitor sar cov main proteas via structur base virtual screen biolog evalu main proteas enzym pro sar cov one promis target covid treatment accord work structur base virtual screen million ligand librari carri rigor filter dock post screen assess compound select biolog evalu show promis inhibit pro enzym obtain hit cb gr gr reason potenc k valu medium high micromolar rang interest potent hit gr suggest act via revers coval mechan gr confirm noncompetit inhibitor seem one kind compar alloster inhibitor discov far moreov three compound small size da interest fit relev bind site possess lead like characterist introduc attract candid futur develop covid treatment | D000086382;D000086402 | T047;T067;T005 |
36,235,243 | cryptamid four pair novel dopamin enantiom trimer periostracum cicada four pair novel dopamin enantiom trimer cryptamid pair previous describ dopamin enantiom dimer isol periostracum cicada cast shell insect cryptotympana pustulata asid pair enantiom eight trimer also elucid regioisom like result mechan format cycloaddit discoveri dopamin trimer rare report come natur product deriv insect | D001688;D006430 | T121;T123;T204 |
36,235,242 | role foxp tumor metastasi interact tradit chines medicin forkhead box protein foxp import transcript factor regulatori cell treg play import role immunosuppress function recent year studi found foxp express mani kind tumor play differ role tumor biolog behavior includ tumor prolifer metastasi drug resist prognosi howev effect foxp tumor metastasi interact tradit chines medicin tcm remain unclear therefor review focus effect foxp tumor metastasi relationship tcm provid evid research therapi clinic set | D051858;D009369 | T191;T123;T116 |
36,235,241 | effect seed oil carica papaya linn food consumpt adipos metabol inflammatori profil mice use hyperlipid diet studi indic differ part carica papaya linn nutrit properti mean use adjuv treatment various patholog | D029441 | T168;T002 |
36,235,240 | quercetin resveratrol differenti decreas express high affin ige receptor fcri human mous mast cell mast cell mc synthes store proinflammatori mediat central import atop diseas asthma atop dermat quercetin resveratrol plant deriv polyphenol compound anti inflammatori properti inhibit mc degranul mediat releas howev under mechan inhibitori effect mc poor understood unclear whether general effect mc phenotyp character compar effect quercetin resveratrol human lad mous mc bmmc mc mediat releas receptor express fcri signal better understand mechan involv quercetin resveratrol mediat inhibit mc activ quercetin signific decreas express fcri bmmc mc although effect mc associ signific reduct cell viabil quercetin also inhibit antigen stimul tnf releas bmmc although neither quercetin resveratrol signific alter antigen stimul bmmc degranul downstream signal event phosphoryl spleen tyrosin kinas syk extracellular signal regul kinas erk resveratrol inhibit erk phosphoryl fcri stimul degranul lad data suggest quercetin resveratrol inhibit human mous mc differenti effect associ modif fcri express signal phosphoryl syk erk mediat releas | D008407;D017455 | T025;T192;T116;T129 |
36,235,239 | format analysi volatil odor compound meat review volatil composit odor meat meat product base precursor present raw meat influenc various pre slaughter factor speci breed sex age feed muscl type furthermor post mortem condit chiller age cook condit cure ferment etc determin develop meat volatil organ compound voc review main reaction lead develop meat voc maillard reaction strecker degrad lipid oxid thiamin carbohydr nucleotid degrad describ import pre slaughter factor post mortem condit influenc meat voc discuss final pros con futur perspect common use sampl prepar techniqu solid phase microextract stir bar sorptiv extract dynam headspac extract analyt method gas chromatographi mass spectrometri olfactometri well electron nose analysi meat voc discuss continu import sensori analysi pinpoint | D009812;D055549 | T109;T120;T070 |
36,235,238 | comparison origanum essenti oil chemic compound antibacteri activ cronobact sakazakii origanum vulgar l oregano aromat plant wide applic food pharmaceut industri cronobact sakazakii high detect rate powder infant formula advers impact suscept individu oregano essenti oil oeo natur antibacteri agent use fight bacteri contamin oeo chemic compound eight oregano varieti analyz gas chromatographi mass spectrometri antibacteri properti assess eight oeo cluster two group divers group group six compound includ p cymen thujen terpinen thymol carvacrol caryophyllen share eight oeo among eight oregano varieti oeo vulgar sc strongest antibacteri activ c sakazaki inhibit zone mm oeo vulgar jx nvi vulgar ehuang vulgar ssp viren also potent moreov antibacteri activ oeo posit correl relat content thymol main oeo antibacteri compound thymol affect normal growth metabol c sakazakii cell destroy bacteri membran decreas intracellular atp concentr thus light antibacteri activ detect oeo eight oregano varieti studi provid theoret foundat oregano cultivar manag develop | D044083;D009822;D031341 | T007;T109;T168;T002 |
36,235,237 | design synthesi bioactiv studi novel tryptophan deriv contain azepin acylhydrazon moieti base scaffold wide use drug design seri novel tryptophan deriv contain azepin acylhydrazon moieti design synthes character evalu biolog activ bioassay result show target compound possess moder good antivir activ tobacco mosaic virus tmv among compound c h v exhibit higher inactiv curat protect activ vivo ribavirin mgl especi show compar activ ningnanmycin mgl meanwhil pleas find almost deriv show good larvicid activ plutella xylostella meanwhil deriv also show broad spectrum fungicid activ | D014027;D014364 | T046;T116;T121;T109;T123;T005 |
36,235,236 | applic biobas solvent asymmetr catalysi necess sustain condit follow twelv principl green chemistri push research develop novel reagent catalyst solvent greener asymmetr methodolog solvent general fundament part develop organ process well separ purif reaction product reason last year applic call green solvent emerg use altern classic organ solvent solvent must present properti low vapor pressur toxic high boil point biodegrad must obtain renew sourc present revis recent applic biobas solvent synthesi optic activ compound employ differ catalyt methodolog includ biocatalysi organocatalysi metal catalysi analyz provid novel tool carri ecofriend organ process | D012997 | T130 |
36,235,235 | essenti oil microemuls inactiv antibiot resist bacteria iceberg lettuc day storag c object studi investig antimicrobi activ essenti oil base microemuls wash water escherichia coli h pseudomona fluorescen iceberg lettuc evalu wash microemuls includ oregano oil lemongrass oil cinnamon oil along plant base emulsifi improv solubl iceberg lettuc inocul min e coli h log cfug p fluorescen log cfug dip treat phosphat buffer salin pbs control ppm chlorin hydrogen peroxid treatment microemuls solut treat leav store c analyz surviv bacteria day efficaci antimicrobi concentr storag time depend log cfug reduct e coli h signific reduct log cfug p fluorescen storag day p lt oregano oil microemuls result best visual appeal iceberg leav inocul e coli h show better improv qualiti iceberg leav inocul spoilag bacteria p fluorescen result suggest cinnamon oregano oil treatment potenti provid natur eco friend effect altern chemic decontamin leafi green elimin e coli h p fluorescen | D000890;D019453;D009822 | T121;T007;T109 |
36,235,234 | first exampl heptazin porphyrin dyad synthesi spectroscop properti prepar first exampl porphyrin link heptazin photoact antenna two entiti link alkyl spacer demonstr activ activ moieti behav electrochem independ hand spectroscopi show exist energi transfer partner | D011166 | T109;T123 |
36,235,233 | biosensor base ion sensit field effect transistor hla mica antibodi detect kidney transplant work demonstr abil ion sensit field effect transistor isfet base immunosensor detect antibodi human leukocyt antigen hla major histocompat complex class relat chain mica sens membran isfet devic modifi function use apt ga strategi surfac properti includ wettabl surfac thick surfac topolog assess modul modif process optim concentr hla mica protein immobil gml dose respons curv show detect rang gml anti hla gml anti mica analyt precis cv found anti hla mica respect moreov electr signal obtain irrelev antibodi consider differ specif antibodi indic specif bind relev antibodi without nois interfer sensit specif experiment set establish antibodi anti hla sensit specif anti mica sensit specif data reveal potenti appli isfet base immunosensor detect relev anti hla mica antibodi especi field kidney transplant | D015374;D016030 | T059;T061;T075 |
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