PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,221,755 | initi experiment multi wavelength eem excit emiss matrix fluoresc lidar detect classif atmospher pollen potenti applic toward real time bioaerosol monitor fluoresc potenti identifi type substanc associ aerosol demonstr use environment studi investig use excit emiss matrix eem fluoresc lidar bioaerosol monitor first eem fluoresc cedar ragwe appl pollen typic bioaerosol found around surround measur use commerci fluoresc spectromet found pattern fluoresc chang depend pollen type excit wavelength meant studi eem fluoresc pattern good paramet identifi pollen type setup simpl eem fluoresc lidar confirm use lidar bioaerosol monitor lidar consist three laser diod one light emit diod output nm nm nm nm respect ultra violet camera len receiv fluoresc spectrum detect unit compar lidar simul result eem fluoresc dataset support possibl perform bioaerosol monitor use eem fluoresc lidar base result current technolog feasibl design bioaerosol detect eem fluoresc lidar propos futur rel time remot sens map atmospher bioaerosol | D011058 | T002 |
36,221,751 | lensfre chip microscopi base singl plane phase retriev propos novel singl plane phase retriev method realiz high qualiti sampl reconstruct lensfre chip microscopi method complex wavefield reconstruct model quadrat minim problem total variat joint denois regular design keep balanc artifact remov resolut enhanc experi built print field portabl platform valid imag perform method resolut chart dynam target transpar cell polystyren bead stain tissu section employ imag test compar state art method method elimin imag degrad obtain higher imag resolut differ multi wavelength multi height phase retriev method method util singl frame intens data record accomplish high fidel reconstruct differ sampl contribut simpl robust data effici solut design resourc limit lensfre chip microscop believ becom use tool telemedicin point care applic | D008853;D011137 | T059;T109;T122 |
36,221,749 | multi scale band limit illumin profilometri robust three dimension surfac imag video rate dynam three dimension surfac imag phase shift fring project profilometri wide implement divers applic howev exist techniqu fall short simultan provid robust solv spatial isol object toler larg variat surfac reflect flexibl tunabl work distanc meter squar level field view fov video rate work overcom limit develop multi scale band limit illumin profilometri ms blip support synergi dual level intens project multi frequenc fring project iter method distort compens ms blip accur discern spatial separ object high vari reflect ms blip demonstr dynam imag translat engin box rotat vase fov work distanc ms blip appli captur full human bodi movement video rate | D021621;D008029 | T068;T062;T073;T060 |
36,221,743 | long term effect blue block spectacl lens color percept use blue block filter increas spectacl len user despit low absorpt blue rang user complain filter affect color percept pilot studi evalu long term use differ blue block filter impact color percept week group normal color vision observ compar control group observ evalu done use fm color assess diagnosi cad achromat point measur result show trend worsen filter | D003118;D005139 | T074;T041 |
36,221,716 | photon spike neural network event driven femtojoul optoelectron neuron base izhikevich inspir model photon spike neural network psnns potenti offer except high throughput energi effici compar electron neuromorph counterpart maintain benefit term event driven comput capabl state art psnn design requir continu laser pump paper present monolith optoelectron psnn hardwar design consist mzi mesh incoher network event driven laser spike neuron design prototyp experiment demonstr event driven neuron inspir izhikevich model incorpor excitatori inhibitori optic spike input produc optic spike output accord optoelectron neuron consist two photodetector excitatori inhibitori optic spike input electr transistor circuit provid spike nonlinear laser optic spike output addit inclus capacitor resistor complet izhikevich inspir optoelectron neuron receiv excitatori inhibitori optic spike input optoelectron neuron develop detail optoelectron neuron model verilog simul circuit level oper various case excitatori input inhibitori input signal experiment result close resembl simul result demonstr excitatori input trigger optic spike output inhibitori input suppress output nanoscal neuron design monolith psnn util quantum imped convers show estim fjspike input trigger output chip nanolas run maximum gspikesecond neural network util simul neuron model conduct simul mnist handwritten digit recognit use fulli connect fc convolut neural network cnn simul result show accuraci unsupervis learn accuraci supervis modifi fc neural network benchmark show psnn achiev topj energi effici correspond throughput energi effici improv compar state art electr neuromorph hardwar loihi neurogrid | D016571;D009474 | T025;T170 |
36,221,700 | fast volumetr imag line scan confoc microscopi electr tunabl len reson frequenc microscop imag biolog tissu particular real time visual neuron activ rapid acquisit volumetr imag pose promin challeng typic two dimension microscopi devis imag system capabl use varifoc len despit conceptu simplic upgrad yet requir addit complic devic compon usual suffer reduc acquisit rate critic proper document rapid neurophysiolog dynam studi implement electr tunabl len etl line scan confoc microscopi lscm enabl volumetr acquisit rate frame per second maximum volum interest axial extent point spread function psf etl oper either stationari reson mode respect reveal signific depth axial penetr reson mode etl microscopi demonstr util etl system volum imag clear mous brain ex vivo sampl vivo brain current studi show success applic reson etl construct high perform axial scan lscm aslscm system advanc rapid volumetr imag would signific enhanc understand various dynam biolog process | D007908;D007909 | T023;T073 |
36,221,682 | hybrid structur network network compar studi deep learn base speckl modul optic coher tomographi optic coher tomographi oct promis noninvas bioimag techniqu resolv sampl three dimension microstructur howev speckl nois impos obvious limit oct resolv capabl propos deep learn base speckl modul oct base hybrid structur network residu dens block u net generat adversari network rdbu net gan conduct comprehens compar studi explor multi type deep learn architectur abil extract speckl pattern characterist remov speckl resolv microstructur first time network compar studi perform custom dataset contain mass general speckl pattern obtain custom built speckl modul oct retin oct dataset limit speckl pattern result demonstr propos rdbu net gan excel abil extract speckl pattern characterist remov speckl resolv microstructur work use futur studi oct speckl remov deep learn base speckl modul oct | D000077321;D041623 | T060;T066 |
36,221,680 | swept wavelength null polarimet high speed weak anisotropi measur null polarimet provid best sensit anisotropi measur far develop detect small optic activ paper revisit null polarimetri origin configur base concept spectral encod light polar order measur unpreced speed either linear circular retard degre sensit use passiv polar optic high speed wavelength swept laser sourc achiev singl pass sensit nradhz nradhz respect linear circular retard consid minimum acquisit time due compact rapid method could implement laser scan microscop great interest reveal low anisotropi biolog tissu | D007834;D055095 | T090;T074;T073 |
36,221,673 | unsupervis despeckl optic coher tomographi imag combin cross scale cnn intra patch inter patch base transform optic coher tomographi oct found wide applic diagnosi ophthalm diseas qualiti oct imag degrad speckl nois convolut neural network cnn base method attract much attent oct imag despeckl howev method general need noisi clean imag pair train difficult captur global context inform effect address issu propos novel unsupervis despeckl method method use cross scale cnn extract local featur use intra patch inter patch base transform extract merg local global featur inform base extract featur reconstruct network use produc final denois result propos network train use hybrid unsupervis loss function defin loss produc nerighborneighbor structur similar despeckl result probabilist non local mean method method well mean squar error featur extract vgg network experi two clinic oct imag dataset show method perform better sever popular despeckl algorithm term visual evalu quantit index | D007091;D041623 | T060;T066 |
36,221,656 | robust categor color constanc along daylight locus red green color defici categor color constanc normal trichromat found robust real scene studi investig categor color constanc red green dichromat anomal trichromat eight dichromat two protanop six deuteranop eight anomal trichromat four protanomal four deuteranomal trichromat eight normal trichromat sort munsel matt surfac berlin kay basic color categori illumin f illumin correl color temperatur k tl illumin correl color temperatur k color constanc quantifi color constanc index result show constanc index dichromat consider signific lower normal trichromat anomal trichromat impair color constanc perform dichromat expect caus larg intra subject variabl color name result indic robust categor color constanc along daylight locus red green dichromat anomal trichromat might contribut cone adapt mechan independ color discrimin mechan suggest color categor color vision defici subject reason without assist artifici equip daili life sunlight common illumin | D055253;D003117 | T047;T040 |
36,221,649 | doubl layer focal plane microscopi high throughput dna sequenc throughput one import properti dna sequenc propos novel doubl layer focal plane microscopi doubl dna sequenc throughput fluoresc channel divid two tube len channel energi split camera adjust take imag correspond differ defocus posit object thus doubl inform capac microscopi microscopi appli gene chip high spatial frequenc good uniform simultan imag two tube littl influenc due spatial averag effect experiment result show imag signal nois ratio snr reduc sequenc throughput doubl | D059014;D008853 | T059;T063 |
36,221,645 | measur natur frequenc mode shape transpar insect wing use common path espi studi common path electron speckl pattern interferometri system uphold natur properti transpar insect wing develop measur wing natur frequenc mode shape first time novel base excit method design enabl simultan applic sinusoid static forc excit wing introduc addit phase moir effect induc amplitud modul employ accur recogn reson state subsequ mode shape visual phase shift real time frame subtract eight pair forew cicada investig first three order natur frequenc wing approxim hz hz hz respect dispers prevent modal coupl camber mode shape exhibit strong spanwis chordwis anisotropi flexur stiff distribut general domin bend twist deform detail high order mode shape show tip exhibit distinct deform indic flexibl cope extern impact load nodal line usual compli direct wing vein higher mode substanti fact vein play import role stiffen membran result excel agreement dynam perform previous studi potenti affect broader communiti optic measur specialist entomologist enhanc understand time averag interferogram insect flight | D005426;D014921 | T017;T040 |
36,221,637 | genet optim mid infrar filter machin learn chemic classifi miniatur mid infrar spectromet present opportun applic rang health monitor agricultur one approach combin array spectral filter infrar photodetector call filter array detector array fada microspectromet paper recent report fada microspectromet tandem machin learn chemic identif work fada microspectromet filter assembl test filter band pass band stop design even span microspectromet oper wavelength rang howev given machin learn classifi train arbitrari filter basi appar even space filter optim simul nois use genet algorithm optim six bandpass filter best identifi liquid gaseous chemic report classifi train optim filter set outperform train even space filter set handpick target absorpt band chemic investig | D000069550;D012031 | T059;T066;T081 |
36,221,625 | analysi peripher arteri diseas pad patient laser speckl measur techniqu diabet foot well known problem among patient suffer peripher arteri diseas pad articl present optic sensor contactless measur anatom site base laser speckl techniqu sensor illumin inspect tissu analyz captur back reflect light time chang speckl pattern occlus test implement provid statist paramet differenti low perfus healthi foot clinic studi subject conduct video analyz two method dynam laser speckl dls laser speckl contrast analysi lasca data analysi includ sever classif model knn model exhibit maximum perform find suggest simpl inexpens system pad monitor design home use andor communiti clinic | D007834;D058729 | T047;T074;T073 |
36,221,618 | diagnosi hlb asymptomat citrus fruit element migrat transform use laser induc breakdown spectroscopi huanglongb hlb one devast bacteri diseas citrus growth cure masteri element migrat transform pattern effect analyz growth crop law element migrat transform citrus growth clear order obtain law element migrat transform healthi hlb asymptomat navel orang collect field taken research object laser induc breakdown spectroscopi lib atom spectrometri techniqu materi compon analysi analyz element composit fruit flesh peel soil know specif process nutrient exchang energi exchang plant extern environ well rule intern nutrient transport distribut energi transform studi element absorpt growth navel orang effect monitor real time hlb inhibitori effect absorpt navel orang order improv detect effici lib coupl svm algorithm use distinguish healthi navel orang hlb asymptomat navel orang classif accuraci compar tradit detect method detect effici lib technolog signific better polymeras chain reaction method provid new mean diagnosi hlb asymptomat citrus fruit | D002957;D032084 | T168;T002 |
36,221,615 | optim multilay structur sensit thz character thin film glucos solut terahertz time domain spectroscopi thz tds shown promis biomed sampl character high character sensit demand due thin film tf featur sampl paper propos optim multilay structur sensit character tf aqueous solut reflect thz tds theoret simul conduct structur optim window sampl mirror structur display best sensit compar sandwich structur tradit thz measur geometri tf glucos solut measur spectral peak introduc propos structur observ result high sensit work provid new way custom multilay structur thz thin film character | D055068 | T059 |
36,221,587 | optim flexibl fiber optic probe epi mode quantit phase imag quantit obliqu back illumin microscopi qobm emerg label free optic imag technolog enabl tomograph quantit phase imag qpi epi illumin thick scatter sampl work present robust optim flexibl fiber optic base qobm system approach enabl silico optim phase signal nois ratio wide paramet space obviat need tedious experiment optim could easili miss optim condit experiment valid simul also present sensit limit probe assess optim probe light weight g compact mm diamet achiev later resolut axial resolut field view near video rate oper hz limit camera phase sensit nm singl qobm acquisit hz lower limit nm via multi frame averag final demonstr util optim probe imag thick fix rat brain sampl l gliosarcoma tumor model fresh excis human brain tissu neurosurgeri acquir qobm imag use flexibl fiber optic probe excel agreement free space qobm system situ well gold standard histopatholog slice tissu process | D005336;D008853 | T059;T090 |
36,221,584 | subsurfac phytoplankton vertic structur lidar observ scs summer monsoon onset subsurfac phytoplankton vertic structur observ first time lidar onset scs summer monsoon base lidar data obtain continu day night measur two week period hybrid retriev method determin vertic structur seawat chlorophyl concentr use lidar data propos compar data obtain lidar retriev ocean color data studi spatial variat hour diurnal variat subsurfac chlorophyl maximum layer scml signific chang depth scml scs may due variat light avail nutrient suppli onset scs summer monsoon preliminari result indic lidar measur allow submesoscal ocean dynam mechan understood new perspect | D010839;D012623 | T167;T002 |
36,221,583 | multispectr higher order fano reson metasurfac base period twist dna like split ring array three modul method activ modul fano reson rare desir howev recent studi most focus singl modul method report use three photoelectr control method tunabl graphen dna like metamateri modul multispectr fano reson demonstr experiment fabric metamateri six photoelectr joint modul pattern joint show differ optoelectr respons characterist ultrahigh modul depth md achiev thz extern laser pump involv combin optoelectr method result show metasurfac modul promis platform higher order fano reson modul communic field | D006108 | T109;T196 |
36,221,562 | free stand plasmon nanoarray leaki optic waveguid sens flat optic nanogr support thin free stand membran offer opportun combin narrowband waveguid mode rayleigh anomali sensit tunabl biosens surfac high refract index si n membran engin lithograph nanogr base plasmon nanostrip demonstr excit sharp waveguid mode lattic reson achiev fine tune optic mode broadband visibl near infrar spectrum full agreement numer calcul possibl allow us select sharp waveguid mode support strong near field amplif extend hundr nanometr grate enabl versatil biosens applic demonstr potenti flat optic platform devis proof concept nanofluid refract index sensor exploit long rang waveguid mode oper sub picolit scale free stand devic configur could engin nanoscal highlight strong potenti flat optic nanoarray optofluid nanofluid biosens | D015374 | T059;T075 |
36,221,530 | effect observ age stimulus size perform cie color match function observ age size stimulus character use field view fov two import paramet affect color match function cmfs human observ also includ cone fundament cmfs model recent propos intern commiss illumin cie contrast great number studi investig perform cmfs character color match mismatch use differ primari set studi investig effect cmfs character two factor studi care design seri test stimuli five color differ magnitud calcul color differ correspond refer stimulus use cie cmfs model stimuli present two fov ie group young senior observ ask judg two test stimuli appear similar refer stimulus forc choic color differ calcul use cie cmfs found higher correl visual color differ judg senior young observ respect regardless actual fov use experi addit though cie cmfs differ paramet set alway better perform predict perceiv color differ fail character effect observ age stimulus size also experi result support cie recommend use cmfs stimuli fov greater cmfs smaller | D003118;D017949 | T025;T041 |
36,221,522 | inform gain commerci spectral filter anomal trichromaci red green color discrimin compromis anomal trichromaci common inherit color vision defici comput analysi test whether three commerci optic filter medium long wavelength stop band increas inform color surfac surfac sampl hyperspectr imag outdoor scene best potenti gain effect number surfac discrimin sole color reach protanomali deuteranomali much less normal trichromaci gain still less lower scene illumin sever color vision defici stop band filter may offer littl improv object real world color discrimin | D003117 | T047 |
36,221,502 | high perform organ upconvers devic photon photon convers effici nm bio imag applic near infrar region demonstr organ upconvers devic ucd success convert input nir light nm nm green emiss ucd nm light irradi exhibit high photon photon convers effici addit linear dynam rang reach db maximum onoff ratio lumin reach guarante clariti imag nm ucd work characterist high effici long wavelength detect make sens long wavelength nir bio imag research | D003952;D017785 | T060;T167 |
36,221,501 | flexibl terahertz metamateri biosensor label free sens serum tumor marker modifi non metal area terahertz thz metamateri rapid label free sens show applic potenti detect cancer biomark novel flexibl thz metamateri biosensor base low refract index parylen c substrat propos biomark modifi non metal area three step modif method simplifi modif step improv modifi effect simul result non metal modif illustr bulk refract index sensit ghzriu achiev larger obtain tradit metal modif ghzriu meanwhil sever fluoresc experi prove uniform modif effect select adsorpt capac non metal modif method concentr carcinoembryon antigen cea biomark breast cancer patient test use thz biosensor found consist result obtain tradit clinic test limit detect reach ngml find demonstr flexibl thz metamateri biosensor extens use rapid detect cancer biomark futur | D015374;D009369 | T059;T075;T191 |
36,221,493 | partial gold coat tilt fbgs enhanc surfac biosens date clear experiment evid gold coat tilt fiber bragg grate tfbgs high sensit plasmon biosensor provid temperatur compens detect analyt concentr picomolar rang optic biosensor bring evanesc wave surround medium make sensit surfac refract index variat use biosens signal bulk refract index chang non use signal biosens dual sensit make prone drift work studi partial gold coat tfbgs around cross section grate present abil discrimin volum surfac refract index chang interest biosens enhanc signal nois ratio effect induc tfbgs transmit amplitud spectra analyz surround refract index sri chang rang gold film biofunction human epiderm growth factor receptor aptam use thiol chemistri detect protein relev cancer biomark gml gml gml demonstr advantag identifi environment perturb bare area tfbgs left function non specif drift could exist sampl elimin wavelength shift relat surfac modif obtain | D015374;D006046 | T059;T075;T196;T121 |
36,221,470 | photon enabl spike time depend convolut neural network real time imag classif photon enabl spike time depend convolut neural network cnn propos manipul photon multidimension paramet term wavelength tempor spatial break tradit cnn architectur map spatial parallel time depend seri structur propos cnn applic real time imag recognit compris photon convolut processor acceler comput involv electron full connect execut classif task time depend seri matrix matrix oper conduct photon convolut processor achiev base multidimension multiplex accumul carrier activ mode lock laser dispers latenc induc dispers compens fiber wavelength spatial separ via waveshap incorpor electron full connect photon enabl cnn proven perform real time recognit task mnist databas handwritten digit predict accuraci photon enabl convent neural network acceler machin learn neuromorph comput potenti wide use inform process comput good classif vowel recognit speech identif | D016571;D055095 | T090;T170 |
36,221,469 | cross talk elimin lenslet array near eye display base eye gaze track lenslet array la near eye display ned recent technic develop creat virtual imag field view one eye problem occur user pupil move la ned eye box ie cross talk make imag look doubl ghost negat impact user experi although eye gaze track mitig problem effect solut studi understand impact pupil size human percept paper redefin cross talk region practic pupil movabl region ppmr differ eye box size consid pupil size human visual percept evalu effect eye gaze track subject imag qualiti three user studi conduct result ppmr found consist human percept cross talk elimin via eye gaze track better understood static gaze scenario although system latenc prevent complet elimin cross talk fast movement larg pupil chang problem great allevi also analyz system delay base ppmr newli defin paper provid optim scheme meet maximum eyebal rotat speed | D005133;D000084542 | T060;T073;T039 |
36,221,463 | quantit phase imag base model transfer learn convolut neural network wide use optic inform process general abil network depend great scale divers dataset howev acquisit mass dataset later annot becom common problem hinder progress studi model transfer base quantit phase imag qpi method propos fine tune network paramet load pre train base model transfer learn enabl network good general abil import featur fusion method base moment reconstruct propos train dataset generat construct rich enough dataset cover situat accur annot fundament solv problem scale represent abil dataset besid featur distribut distanc score fdds rule propos evalu ration construct dataset experiment result show method suitabl differ type sampl achiev fast high accuraci phase imag great reliev pressur data tag general abil data driven method | D003952;D016571 | T060;T170 |
36,221,456 | real time high sensit refract index sens arch optofluid waveguid refract index ri sens play import role analyt chemistri medic diagnosi environment monitor optofluid techniqu consid ideal tool ri sensor configur high integr high sensit low cost howev remain challeng achiev ri measur real time high sensit low detect limit dl simultan work design fabric ri sensor arch optofluid waveguid monitor power loss light pass waveguid sandwich air clad liquid clad test achiev ri detect sampl real time high sensit furthermor numer simul experiment investig show ri sensor design differ geometr paramet cover multipl ri rang high sensit differ applic experiment result illustr sensor capabl achiev superior sensit better mwriu detect limit riu wide linear dynam rang provid promis solut real time high sensit ri sens | D012031 | T059;T081 |
36,221,443 | flexibl transpar cmut array photoacoust tomographi paper report fabric character first flexibl transpar capacit micromachin ultrasound transduc cmut array illumin photoacoust tomographi fabric base adhes wafer bond techniqu pdms backfil approach array maximum transpar visibl light rang bent radius curvatur less mm without structur layer damag center frequenc mhz fraction bandwidth nois equival pressur nep mpa h z array success use limit view photoacoust tomographi wire target demonstr later axial resolut respect db signal nois ratio addit deep tissu photoacoust tomographi also demonstr blood tube within chicken tissu use fabric cmut array | D014057;D014159 | T074;T060 |
36,221,441 | high sensit ser detect non volatil liquid phase system nanoclust pattern optic fiber ser probe use surfac enhanc raman scatter ser spectroscopi detect substanc non volatil system edibl oil biolog cell import issu field food safeti biomedicin howev tradit dri state ser detect planar ser substrat suitabl high sensit rapid ser detect non volatil liquid phase system paper take contamin edibl oil exampl propos situ ser detect method non volatil complex liquid phase system high perform optic fiber ser probe au nanorod cluster success prepar optic fiber facet laboratori develop laser induc dynam dip coat method relat high detect sensit lod moll sudan red moll thiram sunflow oil good reproduc rsd less achiev portabl raman spectromet short spectral integr time even complex edibl oil system addit recoveri rate experi indic reliabl capabl method quantit detect applic work provid new insight high sensit rapid ser detect non volatil liquid phase system optic fiber ser probe may find import practic applic food safeti biomedicin | D055100;D013893 | T073;T131;T121;T109;T197 |
36,221,437 | covid patient new adult onset still diseas case report adult onset still diseas aosd system autoinflammatori ill unknown caus manifest compris fever arthriti arthralgia skin rash high inflammatori marker ferritin level coronavirus diseas covid share sever clinic featur laboratori marker aosd make challeng differenti condit | D001168;D000086382;D005076;D016706 | T047;T184;T067 |
36,221,436 | reduc incid cie infect peri post oper antibiot use crt pd icd procedur higher cardiac implant electron devic cie infect incid observ cardiac resynchron therapi pacemakerdefibril crt pd implant cardiovert defibril icd devic compar tradit pacemak rate report year cie infect manag high morbiditymort previous studi institut demonstr signific reduc cie infect rate peripost oper antibiot given tradit pacemak procedur present studi examin cie infect incid follow peripost oper antibiot crt pd icd procedur patient underw crt pd icd procedur receiv iv cephalexinclindamycin pre hour post procedur follow day oral therapi procedur crt p crt icd mean age time procedur year mean follow durat year cie infect occur patient icd crt p crt amount rate devic year total time cie infect procedur year five infect occur patient repeat procedur studi demonstr administr peri follow post oper antibiot crt pd icd procedur associ low rate cie infect rate infect per devic year compar favor contemporari rate infect per devic year cie infect occur late well beyond year follow prevent arrhythmia devic infect trial largest trial question approach consid pend definit trial | D000900;D058406;D017147;D016459 | T046;T061;T074;T195;T121 |
36,221,435 | intestin infecti diseas increas risk psychiatr disord nationwid popul base cohort studi intestin infecti diseas iid among common diseas preval worldwid iid also one major diseas group highest incid worldwid especi among children older adult observ higher probabl iid patient psychiatr depart tri servic general hospit therefor object investig associ iid risk develop psychiatr disord nationwid popul base studi use databas nation health insur nhi program taiwan studi includ patient compris patient iid studi group patient without iid control group cox proport hazard regress analysi perform calcul hazard ratio psychiatr disord year follow patient iid develop psychiatr disord compar p adjust hazard ratio ahr overal psychiatr disord studi group confid interv ci p specif studi group higher risk develop psychiatr disord includ sleep disord depress anxieti bipolar disord post traumat stress disord ptsd acut stress disord asd schizophrenia mental retard mr substanc abus psychiatr disord furthermor refractori iid seek medic attent iid time increas risk ahr ci p develop psychiatr disord associ iid increas risk develop psychiatr disord novel role etiolog factor develop psychiatr disord deserv attent control pathogen caus iid urgent public health import | D003141;D001523;D013313 | T047;T048 |
36,221,434 | curcumin protect pc cell high glucos induc inflammatori respons regul mir ptlr axi curcumin exert protect effect diabet encephalopathi dn known potent neuroprotect anti inflammatori antioxid anticanc properti howev under mechan curcumin neuroprotect effect result high glucos hg induc injuri remain unknown purpos studi identifi protect mechan curcumin dn | D000310;D003474;D035683;D018696;D010673 | T191;T121;T109;T123;T130;T114;T169 |
36,221,433 | bodi composit pelvic fat distribut associ prostat cancer aggress predict biochem recurr studi evalu effect bodi composit pelvic fat distribut aggress prognosi local prostat cancer studi includ patient underw robot assist radic prostatectomi posit surgic margin clinicodemograph data collect patient medic report pretreat magnet reson imag mri obtain cancer stage review singl radiologist calcul pelvic fat distribut bodi composit correl bodi composit paramet initi prostat specif antigen ipsa gleason score extracapsular tumor extens biochem recurr bcr free surviv ipsa signific associ bodi mass index bmi p pelvic fat volum p perirect fat volum p wherea gleason score signific associ bmi p tumor extracapsular extens signific associ increas periprostat fat volum p patient less subcutan fat thick cm signific poor bcr free surviv p pelvic fat distribut includ pelvic fat volum perirect fat volum periprostat fat volum signific correl prostat cancer aggress patient less subcutan fat increas risk bcr radic prostatectomi | D017430;D011471 | T191;T126;T116;T129 |
36,221,432 | associ card gene polymorph psoriasi vulgari hainan han popul base exon sequenc case control studi psoriasi serious non communic chronic immun inflammatori mediat diseas affect million peopl worldwid effect go beyond skin manifest genom wide associ studi caspas recruit domain famili member card gene gene variant implic associ psoriasi move toward individu therapi discoveri singl nucleotid polymorph snp great import studi aim determin whether card gene suscept gene psoriasi vulgari studi psoriasi patient healthi control subject exom sequenc card gene region upstream downstream kb sequenc snp base associ analysi haplotyp base associ analysi perform snps minimum allel frequenc maf greater bioinformat method use predict impact risk loci gene function total polymorph identifi studi snps exon intron suscept psoriasi p ci bioinformat analysi show rs locat exon led amino acid chang aspart histidin hand result haplotyp base associ analysi show haplotyp card card protect haplotyp diseas p ci frequenc healthi control patient respect card gene associ suscept psoriasi vulgari hainan han popul | D055106;D011565 | T047;T063 |
36,221,431 | assess stress manag coach among nigerian pre servic histori teacher random control studi studi found pre servic teacher common face stress circumst prevent complet academ task effect term psycholog factor intervent pre servic histori teacher nigeria least studi group object studi investig effect stress manag coach among nigerian pre servic histori teacher | D000071195;D000071252 | T065;T097 |
36,221,430 | feasibl modifi invert l shape approach posterolater tibial plateau fractur retrospect studi approach treat posterolater tibial plateau fractur vari among surgeon invert l shape approach known option articl aim introduc new modifi posterolater invert l shape approach isol posterolater tibial plateau fractur studi feasibl medic record patient posterolater tibial plateau fractur review plain radiograph obtain follow period hospit special surgeri hss score use assess function injur limb periop complic record follow total patient posterolater tibial plateau fractur treat use modifi posterolater approach mean age patient year year patient success underw surgeri follow mean durat month month plain radiograph fractur line fuzzi month surgeri disappear month surgeri periop complic occur follow period hss score evalu month surgeri mean score point point includ excel case good case modifi posterolater invert l shape approach advantag small soft tissu dissect fractur reduct direct vision easi intern fixat lower risk neurovascular injuri approach feasibl treatment isol posterolater tibial plateau fractur high qualiti random control trial requir confirm clinic efficaci | D001860;D013978 | T074;T037 |
36,221,429 | differenti express mirna bronchoalveolar lavag fluid plasma patient chronic obstruct pulmonari diseas micro rnas mirna act key regul particip various biolog process role play chronic obstruct pulmonari diseas copd discov howev recent pharmacolog treatment copd focus allevi symptom reduc risk event heterogen copd caus variabl respons pharmacolog intervent copd treatment gradual develop precis medicin integr clinic biomark inform optim person therapi thus target mirna repres promis strategi copd individu therapi twelv copd patient communiti acquir pneumonia normal peopl recruit total rnas collect bronch alveolar lavag cell peripher blood plasma particip mirna profil microarray systemat compar patient differ group bioinformat analysi identifi pathway relev pathogenesi copd next target pathway network map compar differ group obtain differenti express mirna q valu adjust p valu gene ontolog enrich analys show differenti express mirna function regul differ modul cellular compon molecular function biolog process kyoto encyclopedia gene genom enrich analys suggest signal mapk signal pathway ras signal pathway foxo signal pathway oxid stress may particip pathogenesi copd mirna target pathway network novel hsa mir p hsa mir pcdcmapk signal pathway may play role regul copd find demonstr critic role mirna copd molecular patholog data support plausibl mechan mirna may involv develop copd affect inflammatori oxid stress moreov hsa mir cdcmapk signal pathway may contribut pathogenesi copd provid potenti novel therapeut strategi copd | D035683;D029424 | T047;T123;T114 |
36,221,428 | intervent angiographi util adult trauma patient trauma center across unit state observ studi use nation trauma data bank angiographi embol part trauma manag protocol various injuri studi examin use angiographi embol use trauma care across trauma center unit state use nation trauma data bank ntdb dataset retrospect observ studi adult trauma patient year underw convent angiographi without embol includ univari analysi carri describ patient demograph injuri characterist well time angiographi angiographi detail complic outcom surviv hospit discharg yesno one year period preval proport angiographi procedur determin total patient includ year period preval proport angiographi procedur without embol confid interv median age year interquartil rang patient age group male half patient embol procedur perform addit angiographi mean time angiographi minut common embol site pelvi spleen liver studi describ angiographi embol util adult trauma patient trauma center us find provid basi futur studi examin close angiographyembol util specif subpopul creat standard risk stratif tool trauma patient candid procedur | D000007;D004621;D014949 | T061;T037 |
36,221,427 | cola potenti prognost target oral squamous cell carcinoma oral squamous cell carcinoma oscc malign tumor occur oral caviti howev molecular mechan oscc clear bioinformat use screen identifi role collagen type x alpha cola oscc patient oscc recruit clinic follow data record cola express level test pearson chi squar test spearman correl coeffici use analyz relationship prognosi relat paramet patient oscc univari multivari logist regress univari multivari cox proport risk regress use analysi surviv curv drawn bioinformat analysi oscc patient higher express cola poor overal surviv compar oscc patient lower express cola hazard ratio hr p pearson chi squar test show age p tumor grade p cola p signific correl prognosi oscc univari logist regress analysi show age odd ratio confid interv ci p tumor grade ci p cola ci p multivari logist regress analysi show cola ci p signific associ prognosi patient oscc univari cox regress analysi show age hr ci p tumor grade hr ci p cola hr ci p signific correl surviv time oscc patient multivari cox regress analysi show tumor grade hr ci p cola hr ci p signific correl surviv time oscc patient cola signific correl occurr oscc cola high express prognosi patient oscc wors surviv time shorter | D002294;D006258;D009062 | T191 |
36,221,426 | medic use pregnanc birth defect hunan provinc china cross section studi safeti drug use pregnanc attract attent clinician pregnant woman even total societi howev studi medic use pregnanc follow birth defect bds rare chines studi condit medic use pregnanc follow bds hunan provinc china cross section studi carri women use medic pregnanc deliv fetus bds hunan provinc china employ studi descript analysi carri excel data analys perform use chi squar test spss filter total case includ fetus male femal p sever bds lead death uncorrect lifelong deform observ time minor bds observ time use drug categor pregnanc c x degre food drug administr fda pharmaceut manufactur main includ anti hyperthyroid drug anti epilepsi drug prevent miscarriag drug etc popul base data highlight potenti high risk bds aspect drug use pregnanc hunan provinc china drug safeti less kind lower dose better choic pregnant women | D037841 | T098 |
36,221,425 | p p involv pathogenesi endometri thin cross section studi p play role negat regul cell prolifer regul cell apoptosi control growth tumor cell p nuclear protein suppress dna synthesi inhibit cell divis studi aim examin express role p p endometri thin thirti case endometri biopsi diagnos endometri thin assess p p immunohistochemistri march august huazhong univers scienc technolog union shenzhen hospit anoth thirti case normal endometrium period assess control specimen underw histolog analysi p p assess immunohistochemistri statist signific differ age menstrual cycl bmi sex hormon level gravid pariti two group p endometri thin group p express endometri adenoid nucleus cytolymph interstiti cell nucleus normal group p main express endometri adenoid nucleus p signal detect endometri interstiti nucleus p express main detect endometri adenoid nucleus p p amount endometri thin case signific lower normal endometri group correl p p amount studi reveal aberr express p p endometrium might due compensatori effect thin endometrium increas cell prolifer suppress cell apoptosi howev patholog role p p endometri thin contribut cell senesc deserv investig | D019941;D004717 | T023;T123;T116 |
36,221,424 | administr depot gnrh agonist prior program frozen thaw embryo transfer improv live birth rate ovulatori women larg multi center retrospect studi despit gonadotropin releas hormon gnrh agonist pretreat wide use program frozen thaw transfer fet impact live birth rate ovulatori women remain uncertain present studi aim determin gnrh agonist pretreat fet improv live birth rate women undergo vitro fertil fet program fet cycl conduct four infertil center retrospect collect review elig januari decemb patient demograph ovarian stimul paramet pregnanc outcom compar given gnrh agonist pretreat versus pretreat ovulatori women undergo fet cycl total program cycl screen elig cycl includ studi analysi compar group gnrh agonist pretreat n women gnrh agonist group n older vs p higher proport subject previous transfer attempt higher number embryo transfer control confound logist regress result show gnrh agonist pretreat increas odd clinic pregnanc ci ongo pregnanc ci live birth rate ci howev restrict women previous transfer attempt women gnrh pretreat group lower odd achiev live birth ci sensit analysi perform patient male factor infertil caus show gnrh agonist pretreat group lower live birth rate compar gnrh agonist pretreat group ci find suggest gnrh agonist pretreat bring addit benefit live birth rate improv ovulatori women undergo fet cycl therefor pros use gnrh agonist reduc prematur ovul weigh con prolong time pregnanc discomfort result pituitari suppress increas medic cost associ gnrh agonist use | D001723;D007246 | T046;T081;T033 |
36,221,423 | two case extramedullari plasmacytoma small intestin present ileus case report extramedullari extraoss plasmacytoma emp small intestin rare plasma cell neoplasm pcn present abdomin pain nausea vomit etc describ case emp small intestin present ileus | D045823;D007415;D009101;D010954 | T191;T047 |
36,221,422 | new marker short term mortal poor outcom patient acut ischem stroke mean platelet volum lymphocyt ratio mean platelet volum lymphocyt ratio mpvlr novel marker thrombosi inflamm demonstr close link poor cardiovascular diseas prognosi howev correl mpvlr acut ischem stroke ai remain unclear studi therefor aim clarifi relationship mpvlr short term prognosi ai | D002545;D000083242;D020521 | T047;T046 |
36,221,421 | effect dynam quadripolar radiofrequ genitourinari atrophi sexual satisfact systemat review meta analysi physiolog process childbirth menopaus alter vulvovagin aesthet appear reduc sexual satisfact caus symptom vulvovagin atrophi affect woman qualiti life debat whether dynam quadripolar radiofrequ dqrf use improv condit conduct meta analysi studi among patient undergo treatment dqrf | D008593;D011788 | T078;T039 |
36,221,420 | control effect virtual realiti technolog procedur pain children wound meta analysi children undergo wound manipul usual experi pain virtual realiti technolog novel effect non pharmaceut therapi reduc pain children schedul undergo wound manipul howev effect virtual realiti technolog control procedur pain children wound evalu systemat review | D000073818 | T184 |
36,221,419 | prognost nomogram femal patient suffer non metastat posit breast cancer seer base studi paper aim construct valid novel prognost nomogram physician forecast overal surviv os rate femal patient suffer non metastat human epiderm growth element receptor posit breast inform primari femal posit breast cancer patient without metastasi obtain surveil epidemiolog end result seer databas given inclus exclus standard independ variabl obtain great perform univari multivari analys base independ predictor novel prognost nomogram construct predict surviv year os concord index c index receiv oper characterist curv roc calibr plot adopt assess predict power nomogram total elig patient classifi train cohort n verif cohort n random accord identif multivari analysi surviv predict age diagnosi marit status race site stage n stage progesteron receptor pr status estrogen receptor er status surgeri radiat chemotherapi independ nomogram establish appli train cohort nomogram display excel discrimin perform indic c index confid interv year area curv roc auc valu respect calibr plot forecast year os great agreement os femal posit breast cancer patient without metastasi predict construct nomogram basi seer databas precis surviv predict could offer patient | D001943;D049451 | T191;T170;T081 |
36,221,418 | epidemiolog clinic featur matern sepsi retrospect studi whole pregnanc period matern sepsi result poor outcom fetal matern death incid mortal rate matern sepsi vari differ place differ econom develop race medic condit identifi clinic featur determin possibl mechan avoid morbid prevent poor outcom would benefit commit patient therefor epidemiolog studi matern transfer center southeast china aim identifi local diseas featur matern sepsi investig incid risk factor associ matern sepsi progress sever sepsi larg popul base birth cohort local epidemiolog studi conduct tertiari care center guangzhou china total pregnant women experienc childbirth includ studi patient matern sepsi diagnos accord sepsi criterion patient without sepsi period select random control group studi possibl reason postpartum sepsi retrospect analysi cover entir period first trimest puerperium clinic data collect use hospit electron medic record system multivari logist regress use analyz risk factor matern sepsi incid matern sepsi matern mortal fetal mortal respect septic shock associ higher sever ill poor outcom matern fetal death occur pregnanc postpartum sepsi longest onset period associ prematur ruptur fetal membran preeclampsia sepsi import caus matern fetal mortal herein describ epidemiolog studi evalu incid develop prognosi local matern sepsi furthermor characterist matern sepsi like due unknown patholog mechan patient would benefit identifi effect treatment matern sepsi | D011225;D011251;D011645;D018805 | T047;T046 |
36,221,417 | anti age protein klotho associ vitamin b concentr adult previous studi report serum klotho vitamin b level valuabl age relat marker howev studi support associ serum klotho vitamin b level lack investig associ serum klotho vitamin b concentr adult unit state analyt studi sampl age particip nation health nutrit examin survey nhane serum klotho vitamin b collect adult consent use sampl futur particip divid group base estim glomerular filtrat rate egfr level high mlmin low mlmin particip log transform klotho concentr signific correl log transform vitamin b high egfr group low egfr group adjust potenti covari signific associ klotho vitamin b concentr high egfr group beta se contrast signific relationship klotho vitamin b concentr low egfr group beta se serum klotho concentr signific associ vitamin b increas us adult high kidney function vitamin b concentr may import marker klotho concentr older adult | D000375;D014805 | T121;T109;T127;T040;T114;T033 |
36,221,416 | increas frequenc angiotensin convert enzym allel chines han patient idiopath pulmonari fibrosi systemat review meta analysi explor associ angiotensin convert enzym ace insert defect gene polymorph suscept idiopath pulmonari fibrosi ipf | D054990;D007703 | T047;T126;T116;T129 |
36,221,415 | kras nras braf pikca akt signatur colorect cancer patient south eastern romania somat mutat oncogen epiderm growth factor receptor signal pathway play vital role colorect carcinogenesi close link clinic resist monoclon therapi studi analyz mutat frequenc gene compar genet find clinicopatholog variabl order determin diagnost relev alter compar find studi sanger sequenc kras exon nras exon pikca exon braf exon akt exon gene microsatellit instabl msi status analyz use abi analyz cohort romanian colorect cancer crc patient underw surgic resect emerg counti clinic hospit constana romania seri mutat rate kras braf pikca akt gene respect contrast find tumor harbor mutat nras gene notabl kras pikca mutat mutual exclus patient harbor mutat exon codon glyval kras exon codon hisarg pikca find studi general consist data found literatur regard clinicopatholog variabl mutat kras associ distant metastasi time diagnosi mutat braf signific associ msi h contrast msi lmss tumor moreov pikca mutat tend locat proxim segment colon wellmoder differenti compar wild type tumor conclus assess mutat suggest crc patient southeast romania exhibit mutat profil similar popul result could contribut creat better method qualifi patient molecular target therapi obtain better screen strategi | D015179;D048493 | T191;T126;T116 |
36,221,414 | clinic intervent tighter toler fit aesthet hand finger prosthesi via control silicon swell novel speedier versatil altern method tighter toler fit aesthet hand prosthesi convent rectifi stretch affect segment plastic deform method time consum also ineffect stretch irregular non cylindr prosthesi segment apart wrist digit studi investig control silicon swell altern method expand aesthet hand finger prosthesi address tight fit techniqu control swell minim oil uptak littl necessari achiev desir magnitud elastom expans demonstr use experiment test sampl brush coat cosmet grade oil kf cs time appli cosmesiltm sampl obtain elastom expans techniqu stagger oil deliveri use tight fit segment patient prosthesi test fit increment expans till satisfactori outcom achiev percentag circumfer increas swell test sampl rectifi patient prosthes compar valid effect method circumfer increas test sampl coat signific differ p repres unreinforc sampl record circumferenti increas within minut swell oil coat larg correl patient data circumferenti increas oil coat collect record fit rectifi finger prosthes swell expand proxim segment finger prosthes estim within requir oil coat infer lower still swell rapid consist elastom expans enabl prosthet fit rectif achiev much shorten time clinic outcom indic low swell magnitud involv small amount brush coat oil advers effect prosthes none particip patient report incid discern chang import properti prosthes outcom base cosmesiltm kf cs elastom oil combin demonstr control silicon swell involv minim use oil effect method intervent tighter toler prosthet fit silicon hand finger | D001186;D012828 | T074;T109;T122 |
36,221,413 | probiot rifaximin prevent travel diarrhea systemat review network meta analysi probiot rifaximin treatment gut microbiota dysbiosi patient travel diarrhea td prove benefici prevent td howev compar effect research perform systemat review network meta analysi perform clarifi effect prevent td | D004403;D019936 | T007;T047 |
36,221,412 | comparison maxillari incisor retract effect patient first premolar extract damon q invisalign retrospect studi torqu control maxillari incisor import maxillari protrus patient first premolar extract efficaci maxillari incisor retract clear align still controversi retrospect studi aim compar retract effect damon q invisalign applianc patient first premolar extract patient case damon q case invisalign first premolar extract select studi subsequ patient group alloc three subgroup accord pretreat valu u na retract effect maxillari incisor upper lip access variat cephalometr overbit overjet measur treatment durat invisalign month longer damon q month p angular measur u na u sn show lingual crown inclin invisalign group damon q group p evalu linear measur retract maxillari incisor upper lip posit show signific differ p invisalign group also show lingual crown retract labial root deviat compar damon q group subgroup p regard molar relationship invisalign display less class molar relationship damon q group increas overbit anterior incisor also show invisalign treatment group p invisalign suffici effect retract maxillari incisor compar damon q applianc invisalign led lingual inclin movement increas overbit | D009968;D057887 | T074;T190 |
36,221,411 | robot assist rehabilit total knee hip replac surgeri patient systemat review meta analysi studi perform updat current evid evalu effect robot assist rehabilit rar comparison convent rehabilit cr patient follow total knee tkr hip replac thr | D019644;D012371 | T061;T090 |
36,221,410 | anterior segment par plana vitrectomi combin posterior capsulorhexi phacoemulsif trabeculectomi treatment medic uncontrol acut primari angl closur glaucoma retrospect studi explor clinic efficaci quadrupl surgeri anterior segment par plana vitrectomi phacoemulsif posterior capsulorhexi intraocular len iol implant trabeculectomi dual surgeri phacoemulsif iol implant trabeculectomi treat medic uncontrol acut primari angl closur glaucoma apacg clinic data patient eye apacg treat depart ophthalmolog taih hospit retrospect analyz divid group base quadrupl surgeri dual surgeri patient eye underw quadrupl surgeri group patient eye dual surgeri group b chang intraocular pressur iop visual improv complic observ group preoper month month month postop preoper best correct visual acuiti bcva influenc factor postop bcva month month month surgeri mean iop group signific higher group b p signific differ found bcva age gender eye axial length al anterior chamber depth acd pbcva page pey pgender pal pacd comparison postop week signific differ iop bcva group piop pbcva mean iop group signific lower group b month month month postop pmonth pmonth pmonth degre visual acuiti recoveri signific higher group month month month postop pmonth pmonth pmonth treatment incid complic group b signific higher group p clinic efficaci anterior segment par plana vitrectomi combin posterior capsulorhexi phacoemulsif trabeculectomi elicit clinic safeti treat medic uncontrol apacg remark effect lead signific decreas occurr complic | D005901;D015812;D018918;D014130 | T061;T047 |
36,221,409 | sensit specif analys covid screen protocol emerg medic servic stard compliant popul base retrospect studi novel coronavirus diseas covid pandem emerg medic servic em born huge burden transport emerg patient howev protocol effect identifi emerg patient like covid unknown aim evalu diagnost accuraci prehospit covid screen protocol em conduct popul base retrospect studi nara prefectur japan nara prefectur govern implement screen protocol covid compris follow symptom criteria fever cough sore throat headach malais dysgeusia anosmia epidemiolog criteria contact histori confirm covid case peopl upper respiratori symptom travel area high infect rate patient meet least one criterion class consid posit evalu patient region em databas nara prefectur emerg medic allianc total coordin healthcar regist june may result covid revers transcript polymeras chain reaction rt pcr test assess sensit specif posit predict valu ppv negat predict valu npv protocol also assess outcom chang ad vital sign conduct fold fold preval simul screen protocol use patient among test posit em transport protocol sensit specif ppv npv respect addit vital sign bodi temperatur c respiratori rate breathsminut oxygen satur sensit ppv chang respect npv remain fold fold increas diseas protocol ppv would npv would respect addit vital sign ppv would npv would respect covid screen protocol help enabl em transport patient covid ppv ad vital sign variabl may improv diagnost valu preval rate increas | D000086382;D004632 | T047;T093;T061;T058;T067 |
36,221,408 | estim biochem factor affect surviv intens care covid patient undergo chest ct score retrospect cross section studi coronavirus diseas covid rapid spread dead respiratori diseas emerg citi wuhan decemb result rapid widespread transmiss declar pandem march studi evalu mortal prognosi covid gain import aim studi determin factor affect surviv covid patient follow tertiari intens care unit icu undergo chest comput tomographi ct score retrospect cross section studi conduct approv uak univers medic faculti ethic committe juli septemb includ symptomat patient femal male suspect covid underw chest ct scan icu demograph acut physiolog chronic health evalu apach ii chest ct score covid real time polymeras chain reaction rt pcr result laboratori paramet record spss window use data analysi age patient rang mean age year covid rt pcr test posit patient patient die follow icu stay p total invas mechan ventil time p longer blood urea nitrogen bun higher p nonsurvivor patient apach ii score fold higher mortal rate ci signific differ total chest ct score survivor nonsurvivor p chest ct score signific associ mortal covid patient idea covid caus greater mortal patient sever chest ct find chang studi covid need reveal marker affect prognosi mortal period new variant affect world | D000086382 | T047;T067 |
36,221,407 | likelihood approach potenti role gabrg ct ct gene polymorph poor respons carbamazepin therapi pakhtun popul pakistan gamma aminobutyr acid receptor gamma gene gabrg encod gabaa receptor respons fast neuron inhibit polymorph gabgr gene affect clinic respons anti epilept drug a therefor carri updat studi find associ gabrg gene polymorph carbamazepin cbz non respons therapi pakhtun popul | D000927;D011963 | T121;T116;T192 |
36,221,406 | efficaci safeti acupunctur treatment foot drop post stroke protocol systemat review meta analysi foot drop common complic post stroke patient foot drop high risk fall fall relat injuri accord reduc independ qualiti life patient clinic studi confirm acupunctur effect treat foot drop post stroke howev lack systemat review explor efficaci safeti acupunctur treatment studi aim assess efficaci safeti acupunctur treatment foot drop poststrok result random control trial | D015670;D015201;D020427;D012107;D020521;D000078202 | T047;T061;T081;T170;T169;T062;T096;T033 |
36,221,405 | effect erbium famili laser etch shear bond strength enamel surfac meta analysi prisma recent laser etch appeal peopl attent meaning compar effect erbium dope yttrium aluminum garnet er yag erbium chromium yttrium scandium gallium garnet er cr yssg laser etch paramet acid etch bond strength enamel surfac far know still remain relat meta analysi evalu efficaci er yag er cr yssg laser etch shear bond strength sbs bracket bond enamel meta analysi perform accord prefer report item systemat review meta analys conduct literatur search | D005708;D053844;D016910 | T074;T196;T073 |
36,221,404 | trend predict citat topic neuromuscular junction top cite articl sinc use tempor bar graph bibliometr analysi neuromuscular junction nmj myoneur junction chemic synaps motor neuron mn muscl fiber although numer articl publish analys trend predict citat nmj character use tempor bar graph tbg studi identifi domin entiti top cite articl nmj tmnj short sinc verifi improv tbg viabl trend analysi investig whether medic subject head mesh term use predict articl citat | D015706;D055811 | T062 |
36,221,403 | volum predict larg brain metastas hypofraction gamma knife radiosurgeri artifici neural network effect singl session gamma knife radiosurgeri gkrs small metastat brain tumor proven hypofraction gkrs hfgkrs larg brain metastas bm linear quadrat lq model uncertain purpos studi investig volum chang larg bm hfgkrs lq model predict volum chang use artifici neural network ann retrospect investig clinic find patient underw hfgkrs larg bm diamet cm volum cc total tumor extract patient featur random divid larg brain tumor train set larg brain tumor test set predict volum chang hfgkrs use ann model singl layer perceptron slp multi layer perceptron mlp volum reduct hfgkrs larg bm lq model ann model predict volum chang accuraci slp mlp respect even larg bm hfgkrs lq model could good treatment option addit mlp model could predict volum chang accuraci hfgkrs larg bm | D001932;D016634 | T191;T061 |
36,221,402 | analysi surgic outcom patient renal cell carcinoma venous tumor thrombus retrospect observ singl center studi aim studi assess short long term result follow radic nephrectomi renal vein inferior vena cava thrombectomi patient renal cell cancer venous thrombus investig impact various demograph clinic histolog factor overal surviv os medic record adult patient renal cell cancer venous thrombus admit surgeri depart general vascular transplant surgeri retrospect analyz tumor frequent locat right side compar left one vs accord neve zinck classif level venous thrombus follow postop complic note patient one patient neve zinck die intraop pulmonari embol hospit clear cell carcinoma common patholog type report patient thirti nine patient aliv time last follow median os month year os signific better os median month note patient rcc neve zinck compar os median month patient neve zinck vt p higher tumor stage vs p nodal stage n vs n p fuhrman histolog grade g vs g p associ shorter os patient renal cell cancer venous thrombus accept periop risk treat surgic radic nephrectomi thrombectomi perform high volum surgic center safe procedur neve zinck venous thrombus higher tumor nodal stage well higher fuhrman histolog grade associ shorter os | D002292;D007680;D013927 | T191;T046 |
36,221,401 | valu nse predict icu mortal patient septic shock prospect observ studi investig predict valu neuron specif enolas nse intens care unit icu mortal patient septic shock seventi five patient septic shock hospit emerg intens care unit eicu hebei general hospit march septemb includ patient baselin characterist laboratori find collect nse level first fourth day admiss retriev nse nseday nseday nseday nse nseday nseday calcul outcom indic icu mortal patient divid survivor group n nonsurvivor group n multivari analysi perform assess relationship nse icu mortal predict valu nse evalu use receiv oper characterist roc curv signific differ age gender systol blood pressur sbp heart rate hr acut physiolog chronic health evalu ii score apach ii score sourc infect comorbid group p interleukin il nse day nse day signific higher patient nonsurvivor group p apach ii score il lactat lac total bilirubin tbil nse day nse day show weak posit correl icu mortal patient septic shock p multivari logist regress analysi demonstr apach ii score odd ratio confid interv confid interv ci p il ci p nse day ci p independ associ icu mortal sepsi shock patient area curv auc apach ii score il nse day nse day predict prognosi respect p nse day display good sensit specif sn sp predict icu mortal cutoff valu ugl high level nse day independ predictor icu mortal sepsi shock patient may becom good altern option evalu sepsi sever extens studi need futur demonstr prognosi valu nse | D018805;D012772 | T047;T046 |
36,221,400 | new diagnost morpholog paramet carpal tunnel syndrom palmari longus tendon cross section area carpal tunnel syndrom cts correl increas intracarp canal pressur icp effect palmari longus tendon plt load icp document previous research plt load induc greatest absolut increas icp therefor analyz connect plt cts newli made measur plt cross section area pltcsa assum pltcsa reliabl diagnost paramet cts pltcsa measur data acquir patient cts normal subject underw wrist magnet reson imag w mri measur pltcsa level pisiform w mri pltcsa measur outlin plt two differ cutoff valu analysi determin use receiv oper characterist roc analysi mean pltcsa mm normal group mm cts group roc curv analysi conclud best cutoff point pltcsa mm sensit specif area curv ci pltcsa sensit new object morpholog paramet evalu cts | D002349 | T047 |
36,221,399 | bilater vers bilater tri segment endoscop drainag use metal stent high grade malign hilar biliari obstruct multicent random control trial brave studi brave studi bilater endoscop drainag self expand metal stent sem use manag hilar malign biliari obstruct hmbo effect comparison unilater drainag increas drainag area predict prolong stent patenc patient surviv howev report describ util trisegment drainag benefit use trisegment drainag remain unknown thus launch random clinic trial rct compar clinic outcom bilater trisegment drainag use semss patient high grade hmbo | D001650;D002779 | T191;T047 |
36,221,398 | descript cross section studi self manag patient nonvalvular atrial fibril self manag non valvular atrial fibril nvaf character complex divers content inadequ self manag expos patient risk complic stroke bleed assess status predictor self manag nvaf patient descript cross section studi conduct self manag scale atrial fibril use assess status self manag patient receiv warfarin noac aspirin anticoagul therapi general situat questionnair use collect socio demograph clinic data patient total particip complet survey self manag score warfarin group noac group aspirin group anticoagul group respect warfarin group lower educ status associ poor self manag aspirin group comorbid age year p associ poor self manag anticoagul group age year singl poor sleep qualiti perman af associ poor self manag self manag inadequ patient nvaf poor self manag might relat occurr cerebr embol nvaf patient receiv anti thrombot therapi relat young age comorbid age substanti impact self manag perform age type af qualiti sleep marri status associ self manag patient anticoagul | D001281;D000073278;D020521 | T058;T047;T046 |
36,221,397 | gunao yizhi decoct combin donepezil vascular dementia systemat review meta analysi gunao yizhi decoct effect supplement intellig strengthen marrow resolv phlegm reduc turbid clinic use treatment vascular dementia vad howev still lack systemat evalu efficaci safeti review conduct systemat review current evid efficaci safeti gunao yizhi decoct combin donepezil vad | D015140;D004365 | T121;T047;T123 |
36,221,396 | hypercalcemia worsen vitamin supplement sarcoidosi patient case report mani caus hypercalcemia hyperparathyroid malign account case sarcoidosi intak vitamin supplement may also caus hypercalcemia although occurr rate low one involv herein report sarcoidosi patient develop hypercalcemia take cholecalciferol vitamin supplement year | D058186;D006934;D012507 | T047;T037 |
36,221,395 | studi blend teach mode applic base arc motiv model take bioinformat cours exampl advent internet era technolog like big data artifici intellig emerg teach model constant innov blend teach mode combin advantag onlin teach tradit classroom howev process specif teach practic mani problem insuffici use intellig platform insuffici domin posit student difficult maintain high learn motiv long time mere formal blend teach therefor studi first use attent relev confid satisfact motiv model explor applic bioinformat cours blend teach classroom teach mode reconstruct aspect pre class guidanc class research class promot model provid new idea direct teach innov curriculum reform colleg | D019295;D009042 | T078;T091;T080;T041 |
36,221,394 | prognosi tumor immun microenviron patient gastric cancer novel senesc relat signatur cellular senesc stabl state cell cycl arrest play crucial role tumor microenviron tme cancer progress nevertheless accur prognosi gastric cancer gc complic predict due tumor heterogen work aim build novel prognost model gc | D013274 | T191 |
36,221,393 | associ intraop fluid overload postop debrid major sacrum tumor resect propens score match studi intra aortic balloon occlus iabo use reduc intraop bleed facilit success sacrum tumor resect patient experi postop wound heal problem risk factor relat complic clear defin anesthet databas peke univers peopl hospit beij china search patient age year old underw sacrum tumor surgeri applic iabo data patient aortic occlus durat minut collect fifti six patient requir postop debrid wound infect independ risk factor identifi logist regress fluid excess calcul volum infus minus blood loss urin output divid bodi weight kg decis tree analysi reveal cutoff point fluid excess mlkg patient divid high fluid excess group fluid excess mlkg low fluid excess group fluid excess mlkg pair patient generat propens score match psm fluid excess signific higher high fluid excess group vs mlkg p patient requir postop debrid low fluid excess group vs p retrospect psm studi sacrum tumor resect fluid overload relat postop debrid studi need improv clinic prognosi | D006333;D009369;D014883 | T191;T047;T046 |
36,221,392 | examin relat self realize burnout level nurs self realize involv realize one aim reveal hisher potenti self satisfact person accomplish scientif invent import know nurs self realize level variabl affect self fulfil necessari person profession develop nurs studi conduct determin relat self realize burnout level nurs studi cross section studi conduct nurs work ukurova univers faculti medicin hospit adana turkey data collect person inform form self realize sub dimens healthi lifestyl behavior scale maslach burnout scale analys data made spss demo packet program percentag averag varianc analysi student test mann whitney u test ethic board approv institut approv obtain studi self realize score averag nurs self realize score nurs prefer job will found higher burnout level found lower also determin femal nurs experienc emot burnout compar male nurs present studi determin person accomplish score averag higher desensit emot burnout score averag among burnout scale sub dimens lower higher self realize score | D002055;D009726 | T097;T048 |
36,221,391 | fetus bosch boonstra schaaf optic atrophi syndrom character bilater ventricl widen case report relat literatur review bosch boonstra schaaf optic atrophi syndrom bbsoa rare neurodevelopment disord caus loss function variant nuclear receptor subfamili group f member nrf report case fetal bbsoa fetus typic featur bilater ventricl widen late second trimest meanwhil mb delet fragment qq involv whole nrf gene confirm copi number variat sequenc cnv seq combin karyotyp analysi aim provid comprehens prenat clinic manag strategi fetal bbsoa | D008607;D015418;D009896 | T047;T048 |
36,221,390 | differenti benign malign gallbladd wall thicken non contrast mri imag preliminari studi combin diagnost indic synthet evalu diagnost accuraci imag featur differenti benign malign gallbladd wall thicken diseas non contrast mri establish optim diagnost indic total patient wall thicken type gallbladd carcinoma patient benign wall thicken diseas includ diagnost perform six imag featur includ layer pattern weight imag twi diffus weight imag dwi imag twi signal intens papillari growth appar diffus coeffici adc valu lesion liver parenchyma ratio llr gallbladd evalu compar receiv oper characterist roc curv binari logist regress analysi use construct optim combin indic six indic show high diagnost accuraci layer pattern dwi llr highest area curv auc valu follow layer pattern twi twi signal intens adc valu papillari growth statist signific differ auc among indic pairwis comparison combin layer pattern dwi papillari growth shown optim indic binari logist regress analysi auc valu combin higher layer pattern dwi papillari growth p non contrast mri provid sever reliabl indic differenti benign malign gallbladd thicken diseas combin layer pattern dwi papillari growth optim indic | D005705;D008279 | T059;T047;T060;T170 |
36,221,389 | effect safeti repetit transcrani magnet stimul memori disord stroke protocol systemat review meta analysi approxim patient memori impair great negat effect daili life month stroke repetit transcrani magnet stimul rtms wide use rehabilit stroke safe painless noninvas moreov studi investig effect rtms poststrok memori disord psmd howev efficaci rtms consist option stimul frequenc unclear therefor protocol aim evalu clinic effect safeti rtms psmd analyz result random control trial | D020521;D050781 | T061;T047;T062 |
36,221,388 | syphilit osteomyel patient hiv cognit bias clinic reason case report diagnos multifactori multidimension symptom unexplain presumpt diagnosi often challeng infecti diseas specialist | D015658;D010019;D013587 | T047 |
36,221,387 | success treatment talaromyc marneffei pneumonia hiv negat renal transplant recipi case report talaromyc marneffei caus life threaten opportunist fungal infect immunocompromis patient often poorer prognosi non human immunodefici virus hiv infect hiv infect individu delay diagnosi improp treatment | D015658;D016030;D011014 | T050;T061;T047 |
36,221,386 | role ptpb ptpn prognosi solid tumor meta analysi protein tyrosin phosphatas b ptpb play differ role differ solid tumor associ prognosi solid tumor howev role exist controversi meta analysi perform determin whether ptpb relev prognosi solid tumor | D015179;D009369 | T191 |
36,221,385 | long act revers contracept util determin among marri yemeni women childbear age longer want children contracept method long act perman method effect other prevent concept key predictor fertil communiti studi aim determin factor link marri women childbear age longer desir children use long act revers contracept larc yemen use popul base secondari dataset yemen nation health demograph survey ynhds conduct studi analyz weight sampl current marri women age year plan children logist regress analys use investig paramet link present use larc final model specif evalu use good fit test alpha threshold use determin statist signific total sampl ci use contracept larc use ci current contracept user major opt short act revers contracept sarc adjust analysi matern educ husband fertil intent place resid governor wealth group link usag larc accord find women whose spous sought children exampl like use larc share partner fertil intent aor ci p studi marri women reproduct age intent children infrequ use contracept long act method improv women educ socioeconom status could contribut increas use larc | D003270;D000075523 | T121;T061;T039 |
36,221,384 | interact basic diseas low red blood cell count critic murder wound infect osteosarcoma resect wound infect osteosarcoma resect surgic wound infect one common complic patient osteosarcoma resect imper grasp risk factor comprehens therefor studi aim explor risk factor wound infect deepli analyz correl risk factor wound infect | D001859;D012516 | T191 |
36,221,383 | bioinformat analysi clinic signific hla class ii breast cancer human leukocyt antigen hla class ii play critic role antigen present initi immun respons howev correl hla class ii gene express level surviv patient breast cancer still investig analyz microarray rna seq data breast cancer cancer genom atlas tcga genotyp tissu express gtex oncomin databas use bioinformat tool express hla dqa hla dqa hla dqb gene signific upregul breast cancer higher express level hla class ii gene breast cancer especi hla dob hla dqb signific associ better overal surviv furthermor express hla class ii gene close associ surviv breast cancer cancer type cd coexpress hla dob hla dqb also posit associ overal surviv breast cancer patient result indic hla class ii cd may enhanc antitumor immun express pattern may serv potenti prognost biomark therapeut target breast cancer | D001943 | T191 |
36,221,382 | number bed occupi independ risk factor discharg trauma patient reduc burden limit capac medic practition public health system requir time depend character hospit rate infer drawn under caus hospit patient discharg aim studi analyz non medic risk factor lead discharg trauma patient retrospect cohort studi includ trauma patient treat switzerland nation swiss databas qualiti assur surgeri aqc review trauma diagnos accord icd code non medic risk factor includ season chang daili chang holiday number bed occupi trauma patient across switzerland individu patient inform aggreg count per day total patient well count per day level categor variabl interest arima model util model number discharg per day function auto aggress function previous mention risk factor studi includ patient male age standard deviat sd year femal age sd year trauma patient mean length stay sd day patient discharg home n week year season trend observ admiss trend mean number occupi trauma bed rang per day number occupi bed increas weekday decreas holiday number occupi bed posit independ risk factor discharg trauma patient number occupi bed increas given time risk discharg number bed occupi repres independ non medic risk factor discharg capac determin triag hospit patient therefor might increas risk prematur discharg | D006760;D010351 | T058 |
36,221,381 | microrna express within neuron deriv small extracellular vesicl frontotempor degener microrna mirna small non code rna power regul gene express affect express hundr gene mirna pack small extracellular vesicl sev releas extracellular space neuron microglia act local well pass blood brain barrier act system sought understand differ neuron sev mirna express frontotempor dementia ftd alzheim diseas ad healthi age plasma obtain ftd ad healthi age particip match base age sex raceethn addit subset particip also provid pair cerebrospin fluid sampl compar neuron sev mirna plasma cerebrospin fluid neuron sev isol use differenti ultracentrifug antibodi conjug dynabead neuron surfac marker lcam rna sequenc perform ftd ad healthi age particip enrol studi ftd sev mirna c downregul compar healthi control ad mirna mirna downregul compar healthi control ftd use fdr mirna p found increas express cerebrospin fluid compar plasma group ad ftd particip sev mirna c signific downregul ftd compar healthi control may mediat effect microgli direct neuroinflamm interact tar dna bind protein tdp base pathway analysi addit foxo hippo pathway may import mediat ftd base pathway analysi last one sev mirna differenti express plasma cerebrospin fluid pair sampl plasma repres appropri biofluid studi neuron sev mirna | D000544;D000067128;D057180;D035683;D039842 | T047;T116;T026;T123;T048;T114 |
36,221,380 | comparison hallux valgus deform ballerina sedentari individu term balanc paramet aim compar static dynam balanc paramet health qualiti paramet ballerina non ballerina adolesc hallux valgus deform | D003615;D006214;D006215 | T056;T023;T190 |
36,221,379 | baselin repeat measur dbp assess hospit mortal risk among critic ill patient acut myocardi infarct retrospect cohort studi chang diastol blood pressur dbp common patient acut myocardi infarct ami relationship dynam chang dbp hospit mortal among patient ami remain unclear studi aim explor import dbp diseas develop among patient ami perform retrospect cohort studi involv patient medic inform mart intens care iii databas includ patient admit intens care unit icu overal adult ami admiss identifi extract clinic laboratori inform patient ami cox proport hazard model use evalu prognost valu baselin dbp use general addit mix model gamm compar trend dbp time among survivor non survivor adjust potenti confound icu stay patient die mortal rate age non survivor togeth variat dbp time admiss time death great import scientif communiti cox multivari regress analysi display adjust confound factor ascend baselin dbp import hazard factor hospit death hazard ratio confid interv p base gamm dbp death group mark lower surviv group moreov differ two group show increas trend within day icu admiss adjust various variabl result stabl dbp signific contribut hospit mortal among patient ami nonlinear correl baselin dbp hospit mortal among patient ami dbp non survivor decreas within first day icu admiss howev causal deduc data | D001794;D016638;D009203 | T047;T040;T201 |
36,221,378 | explor mechan buyang huanwu decoct treatment spinal cord injuri base network pharmacolog molecular dock buyang huanwu decoct tradit chines medicin decoct wide use treat spinal cord injuri china howev under mechan decoct treat spinal cord injuri unclear studi use network pharmacolog molecular dock examin pharmacolog mechan buyang huanwu decoct prevent treatment spinal cord injuri activ compound target gene buyang huanwu decoct collect tradit chines medicin system pharmacolog swisstargetpredict databas network diagram tradit chines medicin compound target construct cytoscap softwar genet data spinal cord injuri obtain genecard databas accord intersect buyang huanwu decoct target diseas target core target search protein protein interact network construct use string bisogenet platform meanwhil gene ontolog enrich kyoto encyclopedia gene genom pathway perform intersect target metascap molecular dock technolog adopt verifi combin main compon core target total activ compound predict target screen chines herbal medicin buyang huanwu decoct activ compon relat predict target strong link spinal cord injuri studi protein protein interact network total core protein identifi primarili interleukin tumor protein p epiderm growth factor receptor other posit regul kinas activ regul reaction inorgan chemic basic biolog process buyang huanwu decoct cure spinal cord injuri primarili moder immunolog inflamm apoptosi oxid stress involv cancer pathway hif signal pathway p signal pathway mapk signal pathway result molecular dock demonstr primari compon could attach target protein effect final mechan buyang huanwu decoct treatment spinal cord injuri multicompon multitarget multichannel deepli explor offer new idea direct futur research mechan treatment spinal cord injuri | D004365;D013119 | T121;T123;T037 |
36,221,377 | serum anti mllerian hormon recoveri ovarian cystectomi endometriosi retrospect studi among korean women serum anti mllerian hormon samh use marker ovarian reserv mani patient samh level gradual recov fall lowest level surgeri nadir phenomenon studi aim analyz factor relat samh recoveri nadir ovarian cystectomi endometriosi among korean women total patient ovarian endometriosi includ studi samh level measur surgeri least twice within month surgeri patient divid two group recoveri nadir group without recoveri reduct group postop recoveri samh level nadir relat stage bilater lesion surgic method robot assist laparoscop surgeri surgic time nadir group level preoper cancer antigen signific higher decreas signific surgeri reduct group p p addit postop c reactiv protein crp level signific higher nadir group increas signific surgeri reduct group p p increas degre periop crp level show cutoff valu receiv oper characterist curv mgdl area curv p increas serum crp level surgeri signific relat recoveri samh level nadir therefor postop serum crp level could use marker predict samh nadir surgeri | D004715;D010535;D065851 | T047;T061;T060;T191;T042 |
36,221,376 | prognost signific cd antigen newli diagnos multipl myeloma real world retrospect studi prognost valu plasma cell cd express patient multipl myeloma mm report mani studi result controversi studi aim examin prognost signific cd mm patient eighti seven patient newli diagnos mm enrol studi clinic characterist immunophenotyp cytogenet retrospect analyz explor prognost signific cd express multiparamet flow cytometri use detect mm bone marrow sampl patient patient divid group base whether express cd cd group cd group cycl chemotherapi overal respons rate cd patient lower cd patient vs p surviv analysi show median progress free surviv pfs month cd group month cd group p median overal surviv os patient cd group month versus reach cd group p addit among high risk patient detect fluoresc situ hybrid fish median pfs month cd group month cd group p median os cd group cd group month month respect statist signific differ p studi confirm cd patient mm wors prognosi cd patient mm among patient high risk cytogenet exist cd negat identifi mm patient poor pfs os | D009101 | T191 |
36,221,375 | persist tolvaptan medic autosom domin polycyst kidney diseas retrospect cohort studi use shizuoka kokuho databas autosom domin polycyst kidney diseas adpkd rare hereditari diseas lead end stage renal failur approxim half patient seventi year age import continu take tolvaptan control diseas progress howev adher tolvaptan real world set rather random control trial rcts suffici report aim investig tolvaptan persist among patient adpkd use larg claim databas use shizuoka kokuho databas identifi patient diagnos adpkd prescrib tolvaptan march septemb japan persist rate tolvaptan medic estim kaplan meier analysi patient background factor associ treatment discontinu explor evalu log rank test identifi elig patient adpkd among patient use tolvaptan medic follow patient whose median treatment durat month persist rate month estim confid interv respect exploratori analysi factor obvious associ tolvaptan discontinu persist rate tolvaptan patient adpkd real world set may lower previous rcts innov method particular japan analyz adher use larg claim data chang way clinic epidemiolog research health polici rare diseas design futur | D016891 | T047;T019 |
36,221,374 | learn curv microscop unilater laminectomi bilater decompress surgeri use cumul summat test learn curv retrospect observ studi purpos studi character learn curv singl level unilater laminectomi bilater decompress lumbar spinal stenosi use learn curv cumul summat test unilater laminectomi bilater decompress lumbar spinal stenosi propos potenti benefit minim surgeri relat instabl compar tradit bilater laminectomi preserv posterior stabil structur contralater facet joint neural arch due narrow surgic corridor consid exhibit steep learn curv type minim invas procedur howev report avail regard learn curv unilater laminectomi bilater decompress learn curv singl surgeon perform singl level unilater laminectomi bilater decompress assess use learn curv cumul summat test analysi surgeon minim experi open decompress laminectomi previous experi unilater laminectomi bilater decompress procedur success defin oper time less minut surgeri relat complic record total consecut patient underw primari singl level unilater laminectomi bilater decompress singl spine surgeon includ mean oper time unilater laminectomi bilater decompress minut mean oper time earli learn period th case minut late learn period th case minut respect overal complic rate major complic occur earli learn period learn curv cumul summat test signal compet unilater laminectomi bilater decompress th oper indic surgeon reach compet level addit base cumul summat test surgeon seem maintain compet procedur studi show surgic experi reduc oper time surgeri relat complic inexperienc surgeon achiev accept outcom unilater laminectomi bilater decompress minimum case unilater laminectomi bilater decompress requir reach compet level surgeri | D013130 | T020 |
36,221,373 | cuproptosi relat gene signatur predict prognosi lung adenocarcinoma lung cancer lc common malign high mortal rate lung adenocarcinoma luad one common patholog type cuproptosi recent discov new type cell death depend mitochondria howev role cuproptosi luad unknown obtain luad transcriptom data cancer genom atlas tcga long strand non code rna lncrnas base cuproptosi prognosi associ luad construct prognost multi lncrna character divid tcga luad train set valid set prove feasibl sampl divid high risk group low risk group gene ontolog go kyoto encyclopedia gene genom kegg analys use evalu potenti biolog function explor relationship risk model immun identifi differenti express lncrnas associ luad prognosi construct prognost model kaplan meier k analysi reveal prognost model luad prognosi risk assess model good reliabl predict prognosi luad abl improv predict abil tumor mutat burdern singl sampl gene enrich analysi ssgsea reveal risk subgroup associ immun relat function prognost model base cuproptosi lncrna import valu predict surviv luad patient | D000230;D008175;D062085 | T191;T123;T114 |
36,221,372 | atezolizumab plus bevacizumab treatment unresect hepatocellular carcinoma progress molecular target therapi multicent prospect observ studi evalu efficaci atezolizumab plus bevacizumab treatment patient hepatocellular carcinoma hcc previous treat molecular target agent mtas thirti one patient treat atezolizumab plus bevacizumab unresect hcc previous treat mtas enrol studi treatment line rang second sixth line treatment effect hcc differ first line treatment treatment effect determin use respons evalu criteria solid tumor recist modifi recist treatment respons differ mta immedi prior atezolizumab bevacizumab treatment tumor treat lenvatinib follow atezolizumab bevacizumab show rapid growth short period time follow shrinkag howev patient receiv ramucirumab sorafenib regorafenib show chang like differ mechan action mta administ immedi beforehand side effect profil differ observ imbrav phase studi atezolizumab plus bevacizumab show advers event relat hepat reserv patient treat combin atezolizumab bevacizumab lenvatinib therapi may experi rapid tumor growth subsequ shrinkag | D000970;D006528;D008113 | T121;T109;T191 |
36,221,371 | systemat investig clinic signific prognost valu cbxs esophag cancer esophag cancer esca one aggress malign tumor announc ninth common cancer sixth lead caus cancer relat death world chromobox famili member cbxs import epigenet regul relat transcript target gene role cbxs carcinoma report mani studi howev function prognost valu differ cbxs esca still larg unknown articl first perform differenti express analysi sever method includ oncomin gene express profil interact analysi result led us determin differenti express cbxs pan cancer especi esca evalu prognost valu differ cbx messeng rna mrna express patient esca kaplan meier plotter human protein atlas databas addit use cbioport explor genet alter mutat cbxs esca simultan correl express level immun infiltr esca visual timer final biolog function cbxs esca obtain biolog enrich analysi includ gene ontolog kyoto encyclopedia gene genom express level cbx cbx esca tissu increas signific express level cbx decreas differenti express analysi addit cbx signific relat clinic cancer stage diseas free surviv esca patient high mrna express cbx relat short overal surviv patient esophag squamous cell carcinoma high mrna express cbx relat short overal surviv patient esophag adenocarcinoma indic cbx may potenti prognost biomark surviv esca patient besid express cbxs signific relat infiltr varieti immun cell includ six type cd posit lymphocyt macrophag neutrophil bursindependentlymphocyt cd posit lymphocyt cell dendrit cell esca moreov found cbxs main associ inhibit cell cycl apoptosi pathway enrich analysi indic cbxs correl gene enrich mismatch repair dna replic cancer pathway spliceosom research may provid new insight choic prognosi biomark cbxs esca | D004938;D000077277 | T191 |
36,221,370 | gamma glutamyl transferas platelet ratio noninvas evalu liver fibrosi patient primari biliari cholang gamma glutamyl transferas platelet ratio gpr report effect aspart transaminas platelet ratio index apri fibrosi index base factor fib show fibrosi stage patient chronic hepat b demonstr apri fib success assess fibrosi primari biliari cholang pbc investig effect gpr predict advanc fibrosi cirrhosi patient biopsi proven untreat pbc total patient biopsi proven pbc includ studi biopsi fibrosi stage patient diagnosi compar use apri fib gpr valu diagnost accuraci gpr detect advanc fibrosi cirrhosi also investig area receiv oper characterist curv auroc gpr cutoff point sensit specif detect advanc fibrosi studi show gpr sensit apri fib detect advanc fibrosi patient pbc gpr could use effect noninvas marker pbc show advanc fibrosi time diagnosi | D019694;D008105 | T047 |
36,221,369 | associ gestat diabet mellitus advers obstetr outcom among women advanc matern age retrospect cohort studi explor associ gestat diabet mellitus gdm matern neonat advers outcom among women advanc matern age retrospect cohort studi includ elig pregnant women nation vital statist system databas particip divid two group gdm group n non gdm group n univari multivari logist regress analys use assess associ gdm matern neonat outcom addit also adopt subgroup analysi analyz associ detail base gestat weight gain gwg level risk advers outcom present use odd ratio confid interv ci adjust covari gdm increas risk neonat assist ventil ci neonat intens care unit nicu ci admiss neonat low apgar score fifth minut ci neonat high birth weight ci neonat prematur birth ci mother enter intens care unit icu ci mother took cesarean section ci among women advanc matern age studi find indic gdm risk factor obstetr outcom among women advanc matern age import implic manag gdm women advanc matern age | D016640;D000078064 | T047;T033 |
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