PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,221,368 | clinic efficaci acupunctur patient adhes intestin obstruct meta analysi adhes intestin obstruct aio common surgic emerg surgic explor consider risk intestin injuri surgic treatment may great reduc qualiti life surgeri caus aio oper nonsurg treatment effect approxim patient adhes small bowel obstruct asbo howev high recurr mortal rate asbo concern moreov ideal manag method asbo remain debat studi shown acupunctur also promot postop gastrointestin function recoveri prevent postop complic nausea vomit viscer pain | D015670;D007415 | T061;T047 |
36,221,367 | central hemodynam discrep central blood pressur brachial blood pressur despit similar brachial blood pressur central hemodynam could differ object present studi investig factor could influenc discrep central bp cbp brachial blood pressur six hundr forti seven patient male year old enrol use applan tonometri cbp noninvas deriv median differ brachial systol bp bsbp central systol bp csbp mm hg defin discrep bsbp csbp differ mm hg adjust cbp popul divid group accord cbp group csbp mm hg group mm hg csbp central hemodynam paramet patient includ augment pressur augment index ai heart rate bpm adjust augment index ai hr subendocardi viabil ratio measur use multivari logist regress analysi evalu factor could influenc discrep bsbp csbp age gender augment pressur ai ai hr correl discrep bsbp csbp ai hr signific correl discrep bsbp csbp coeffici p group coeffici p group coeffici p group group male gender signific correl discrep bsbp csbp coeffici p group coeffici p group present studi arteri stiff might affect discrep bsbp csbp also male gender close relat discrep bsbp csbp especi csbp mm hg csbp discrep csbp bsbp consid understand central hemodynam | D001916;D059289 | T023;T046;T047 |
36,221,366 | surviv women pregnanc associ breast cancer accord clinic characterist propens score match studi recent year postpon childbear increas preval pregnanc associ breast cancer pabc pabc poorer prognosi breast cancer associ pregnanc non pabc due delay diagnosi aggress subtyp addit pregnanc predict poor prognosi subject debat thus analyz effect known prognost factor pregnanc prognosi pabc retrospect analyz women age year diagnos breast cancer bc patient distribut pabc non pabc group propens score match perform adjust baselin characterist primari endpoint overal surviv os bc specif surviv bcss secondari endpoint differ prognosi accord bc subtyp recruit patient bc pabc patient pabc younger tend tripl negat bc tnbc subtyp non pabc patient match non pabc patient show signific wors mean surviv rate unmatch non pabc patient patient pabc signific wors os bcss non pabc multivari analys patient pabc lumin b ki tnbc subtyp wors os bcss patient non pabc patient pabc poorer prognosi non pabc patient adjust sever prognost factor differ particular signific patient lumin b tnbc subtyp | D001943;D011252;D064726 | T191 |
36,221,365 | vertebr arterioven fistula avf vertebr arteri aneurysm neurofibromatosi type case report systemat review neurofibromatosi type nf caus mutat nf gene long arm chromosom affect skin nervous system eye skeleton system vertebr arterioven fistula avf associ neurofibromatosi type nf rare | D000783;D001164;D004621;D009456;D020217 | T047;T046;T037;T061;T191;T190 |
36,221,364 | antibodi toxoplasma gondii posit serum aqueous humor diagnos clinic suspect ocular toxoplasmosi case report previous diagnosi ocular toxoplasmosi base clinic symptom toxoplasma serolog check serolog indic often reflect real intraocular situat may even mislead clinician make wrong judgment | D014122;D014126 | T047;T204 |
36,221,363 | nasal protect strategi reduc incid nasal pressur injuri nasotrach intub meta analysi trial sequenti analysi nasal pressur injuri serious problem nasotrach intub perform systemat review meta analysi determin whether use nasal protect strategi protect dress modifi fixat method tracheal tube reduc incid nasal pressur injuri nasotrach intub | D007442;D012121 | T061 |
36,221,362 | clinic effect hyperton sodium lactat infus intraop brain relax patient undergo schedul craniotomi supratentori brain tumor resect studi protocol singl center doubl blind random control phase ii pilot trial hyperosmolar solut prescrib neurosurgeri patient provid satisfactori intraop brain relax lower cerebr injuri relat surgic retractor mannitol tradit consid first choic solut brain relax neurosurgeri patient hyperton sodium lactat infus report provid higher longer osmot effect compar mannitol sever brain injur patient prevent impair cerebr energet relat brain injuri date clinic effect hyperton sodium lactat infus never studi neurosurgeri patient hypothesi studi hyperosmolar sodium lactat infus may provid satisfactori intraop brain relax patient undergo schedul craniotomi supratentori brain tumor resect | D019354;D015173 | T121;T109;T191 |
36,221,361 | refer interv complet blood count paramet individu age year guizhou china strobe compliant retrospect studi refer interv complet blood count cbc paramet common base healthi individu age year howev valu optim correct clinic diagnosi older individu eg year although refer interv age group report china popul base report guizhou provinc total healthi adult male femal age year recruit affili hospit zunyi medic univers guizhou cbc paramet detect sysmex xn automat hematolog analyz refer interv compon analyz accord guidelin intern feder clinic chemistri studi report refer interv cbc paramet signific differ examin refer interv differ gender group especi rbc relat paramet compar nation standard convent refer interv cbc paramet decreas present studi provid local refer interv cbc paramet individu age year guizhou china result sex specif result show lower valu compar common use refer interv china therefor attent paid differ accur refer interv facilit clinic diagnosi decis make popul | D006405 | T091 |
36,221,360 | controversi express sox gastric cancer correl helicobact pylori infect meta analysi express sex determin region sri like high mobil group hmg box sox gastric cancer prognosi patient controversi studi analyz relationship sox express baselin data clinicopatholog paramet prognosi helicobact pylori infect patient gastric cancer provid new supplement diagnosi treatment gastric cancer | D016481;D016480;D013274 | T007;T047;T191 |
36,221,359 | real world studi trastuzumab pertuzumab combin chemotherapi neoadjuv treatment patient posit breast cancer clinic trial shown trastuzumab h pertuzumab p combin chemotherapi neoadjuv therapi increas patholog complet respons pcr rate patient human epiderm growth factor receptor posit breast cancer howev date china real world current limit clinic data patient posit breast cancer receiv hp combin chemotherapi neoadjuv therapi institut march februari retrospect analyz advers reaction evalu use ctcae version primari endpoint total patholog complet respons tpcr yptisypn secondari endpoint breast patholog complet respons bpcr yptis axillari patholog complet respons apcr ypn factor influenc tpcr also analyz total patient includ analysi treat h p taxan carboplatin tcbhp h p taxan thp sequenti anthracyclin cyclophosphamid follow h p taxan ac thp overal tpcr rate tcbhp thp ac thp respect tpcr rate hormon receptor hr negat group higher hr posit group overal bpcr rate apcr rate univari analysi hr status treatment regimen relat factor affect tpcr multivari analysi hr status treatment regimen independ predictor tpcr p p p level toxic rate tcbhp slight higher thp ac thp hp combin chemotherapi achiev high pcr rate tcbhp regimen highest pcr hr negat tumor demonstr higher pcr hr status treatment regimen independ predictor tpcr advers reaction control | D001943;D020360 | T191;T061 |
36,221,358 | primari bronchial schwannoma case report bronchial schwannoma extrem rare among benign tracheobronchi tumor littl known epidemiolog optim clinic manag report case bronchial schwannoma young japanes man clinic implic epidemiolog symptom diagnosi treatment bronchial schwannoma | D001984;D009442 | T191 |
36,221,357 | brain metastasi colorect cancer treatment surviv prognosi investig clinic characterist surviv prognost factor treatment brain metastasi bm colorect cancer crc twenti one patient bm crc retrospect review predict factor bm prognost factor diagnosi bm examin univari multivari cox analysi time develop extracrani metastas includ lung bone liver occurr bm record separ median overal surviv time month univari prognost analysi median surviv multimod therapi better unimod therapi month vs month p addit median surviv karnofski perform status kps bm lesion primari tumor stage ii iii extracrani lesion extracrani metastasi much better group p although signific differ median surviv patient receiv combin treatment bevacizumab treatment bevacizumab associ better surviv month vs month p time interv bone liver lung metastas bm month respect base multivari cox analysi kps treatment modal independ prognosi factor p p respect crc patient high kps multimod treatment improv surviv | D001932;D015179 | T191 |
36,221,356 | lung adenocarcinoma harbor complex eml alk fusion braf co mutat respond alectinib echinoderm microtubul associ protein like gene anaplast lymphoma kinas gene eml alk frequent fusion variant alk rearrang non small cell lung cancer nsclc widespread applic next generat sequenc ngs fusion co mutat eml alk discov complex co mutat eml alk fusion togeth braf though rare occur also deserv attent determin standard care patient herein report case lung adenocarcinoma harbor complex alk fusion coexist braf mutat test dna ngs prior treatment | D000077192;D002289;D008175 | T191 |
36,221,355 | thorac perfus lobaplatin combin endostar treat malign pleural effus meta analysi systemat review lobaplatin new platinum base cytotox chemotherapeut agent endostar endogen angiogen inhibitor implic anti tumor activ studi investig efficaci safeti thorac perfus lobaplatin combin endostar treatment malign pleural effus mpe | D016066 | T047 |
36,221,354 | explor hub gene involv pcos use biolog informat method aim studi find under gene interact mechan crucial polycyst ovarian syndrom pcos analyz differenti express gene deg pcos non pcos subject | D019295;D011085 | T047;T091 |
36,221,353 | portal mesenter venous calcif patient advanc cirrhosi incid portal mesenter venous calcif patient cirrhosi rare report also difficult determin vascular lesion preoper imag examin liver cirrhosi patient associ portal venous calcif high postop complic mortal poor prognosi | D002114;D004932;D006975 | T047;T046;T020 |
36,221,352 | clinic effect anwei qingyou recip peptic ulcer effect level egf pge retrospect studi investig effect anwei qingyou formula clinic treatment patient peptic ulcer pu effect level epiderm growth factor egf prostaglandin e pge | D000897;D016481;D016480;D010437 | T121;T007;T047 |
36,221,351 | clinic use mac bind protein glycosyl isom diagnos liver cirrhosi signific fibrosi patient chronic liver diseas retrospect singl center studi accur diagnosi liver cirrhosi lc signific fibrosi patient chronic liver diseas cld import mac bind protein glycosyl isom mbpgi emerg novel serum biomark liver fibrosi howev insuffici clinic data mbpgi avail patient cld therefor perform retrospect cohort studi investig clinic use serum mbpgi assess lc signific fibrosi cld patient retrospect review cld patient measur serum mbpgi kosin univers gospel hospit januari decemb multivari logist regress analys conduct identifi independ factor associ lc diagnost power serum mbpgi lc signific fibrosi f evalu compar serum biomark use receiv oper characterist curv area curv auc total patient enrol studi mbpgi adjust odd ratio aor confid interv ci fibrosi index base four factor aor ci identifi signific independ factor lc auc mbpgi lc signific fibrosi compar fibrosi index base four factor aspart aminotransferas platelet ratio index gamma glutamyl transpeptidas platelet ratio optim cut valu mbpgi lc signific fibrosi respect serum mbpgi level signific correl liver stiff measur serum mbpgi reliabl noninvas method assess lc signific fibrosi patient cld | D008107;D005723 | T047;T126;T116;T033 |
36,221,350 | preval elev alanin aminotransferas alt pregnanc cross section labor deliveri base assess sinc liver test routin check pregnanc preval abnorm liver test liver relat abnorm pregnanc us base popul known sought determin preval abnorm alanin aminotransferas alt among pregnant individu present labor deliveri evalu evalu preval under diagnos liver condit prospect studi evalu liver test consecut sampl obtain labor deliveri unit patient characterist compar without abnorm alt without abnorm alt without liver relat diagnosi made clinic practic use test continu measur fisher exact test appropri categor measur logist regress util identifi factor associ abnorm alt subcohort determin predictor abnorm alt without known liver relat diagnosi collect laboratori specimen patient patient elev alt iul alt alt alt patient alt iul lts check routin pregnanc care individu abnorm lt preeclampsia cholestasi pregnanc hepat c chronic liver diseas diagnos signific demograph clinic differ without alt whether liver diseas diagnosi made identifi preval abnorm lts consecut pregnant individu present l liver relat condit diagnos clinic practic among liver relat diagnos pe icp common among individu alt iuml chronic liver diseas rare diagnos evalu role alt test part routin prenat care need particular establish baselin preval liver test abnorm pregnanc independ associ pregnanc outcom | D008107 | T047;T033 |
36,221,349 | novel nomogram predict surviv patient nonsurg thorac esophag squamous cell carcinoma treat imrt retrospect analysi purpos studi evalu sever preradiotherapi serum inflammatori indic includ neutrophil lymphocyt ratio nlr platelet lymphocyt ratio plr system immun inflamm index sii system inflamm score sis compar indic highest valu predict surviv inflammatori marker combin tradit prognost factor novel nomogram model develop predict overal surviv os progress free surviv pfs patient esophag squamous cell carcinoma total patient enrol kaplan meier method univari multivari analys use compar surviv differ total patient met elig criteria surviv number year respect os pfs rate estim year respect differ patient os pfs signific univari analysi appli base inflamm base measur multivari analysi show tumor length tumor stage tumornodemetastasi stage chemotherapi sis valu predict variabl os pfs nomogram model establish base multivari model train data set good predict abil unadjust c index ci ci os pfs respect studi show sis base nomogram could accur predict os pfs patient esophag squamous cell carcinoma | D004938;D000077277;D050397 | T191;T061 |
36,221,348 | efficaci predictor third generat cephalosporin treat spontan bacteri periton third generat cephalosporin rd gcs recent becom controversi first line strategi empir spontan bacteri periton sbp treatment studi aim identifi sbp treatment efficaci predictor rd gcs | D001424;D003428;D010538 | T047;T046 |
36,221,347 | spadework integr medicin base critic pathway facial palsi web base survey tradit korean medicin doctor patient affect facial palsi consult tradit korean medicin doctor convent medicin doctor consid optim approach vari depend progress diseas need facial palsi manag integr medic care howev critic pathway develop manag facial palsi integr medic perspect aim studi explor treatment util status awar facial palsi b understand possibl tradit korean medicin modal c suggest intervent includ integr medic servic treat facial palsi regard exist paper relev field draft questionnair first establish eight person develop committe compris review draft modifi item questionnair independ committe author present studi recheck valid reliabl modifi item questionnair questionnair develop compris item includ demograph characterist clinic statement recognit demand direct improv qualiti newli develop critic pathway use servic associ korean medicin medistream questionnair sent via web base survey tradit korean medicin doctor total valid questionnair collect tradit korean medicin doctor total doctor respond state util integr medic system various form acupunctur herbal medicin thermal therapi present key tradit korean medicin treatment includ critic pathway establish integr medic servic convers corticosteroid antivir blood sugar manag chosen critic among convent medic treatment consid respons collect present studi progress natur facial palsi various intervent convent tradit korean medicin servic need includ relev critic pathway critic pathway develop base present studi establish relev clinic practic guidelin could made avail integr medic system | D020330;D005158;D055048 | T091;T047;T184 |
36,221,346 | appropri tube temperatur fiberopt bronchoscop guid intub thermal soften doubl lumen endotrach tube consort compliant articl compar effect thermal soften doubl lumen endotrach tube dlt differ temperatur fiberopt bronchoscopi fob guid intub | D001999;D007442 | T061;T060 |
36,221,345 | potenti benefit endothelin receptor antagonist therapi idiopath pulmonari fibrosi meta analysi result random control trial fibrot diseas take heavi toll term morbid mortal equal even greater caus metastat cancer meta analysi aim evalu effect endothelin receptor antagonist idiopath pulmonari fibrosi | D065128;D054990 | T121;T047 |
36,221,344 | efficaci safeti vedolizumab inflammatori bowel diseas systemat review meta analysi random control trial vedolizumab human monoclon antibodi inhibit gut select integrin surfac leukocyt prevent traffick gastrointestin tract ultim achiev effect suppress intestin inflamm studi aim evalu efficaci safeti vedolizumab treatment inflammatori bowel diseas | D003093;D003424;D015212 | T047 |
36,221,343 | difficult remov tracheal tube general anesthesia case report laryng injuri common endotrach intub present vari degre edema ulcer granul limit vocal cord movement usual result lumen narrow case laryng edema common complic intub usual caus direct pressur inflammatori reaction caus endotrach intub contact surfac | D007819;D007830 | T023;T046;T030 |
36,221,342 | art therapi adjuv treatment schizophrenia protocol updat systemat review subgroup meta analysi random clinic trial follow prisma guidelin efficaci art therapi adjuv treatment schizophrenia remain inconclus variat effect art therapi schizophrenia type schizophrenia sever schizophrenia type art therapi follow durat differ popul never systemat assess object studi systemat evalu effect art therapi schizophrenia determin whether potenti influenc factor affect effect art therapi | D001155;D012559 | T061;T048 |
36,221,341 | therapeut effect acupunctur moxa combust prostat hyperplasia acupunctur moxibust use thousand year china divers condit report combin effect manag benign prostat hyperplasia bph answer question design prospect studi present protocol describ detail random control trial rct | D015670;D011470 | T191;T061;T047 |
36,221,340 | traumat later atlantoaxi disloc combin type ii odontoid fractur patient ankylos spondyl case report traumat later atlantoaxi disloc aad combin odontoid fractur extrem rare standard applic manag traumat later aad still flux due infrequ injuri | D001268;D050723;D004204;D019838;D009809;D016103;D013123;D013167 | T023;T047;T030;T037;T061 |
36,221,339 | role hepat reserv mortal cirrhot patient small hepatocellular carcinoma receiv radiofrequ ablat although radiofrequ ablat rfa consid curat treatment earli stage small hepatocellular carcinoma hcc long term prognosi suboptim major complic cirrhot patient usual relat poor prognosi includ esophag varic bleed ascit hepat encephalopathi studi aim evalu role liver reserv mortal rfa earli stage hcc among cirrhot patient accord presenc number complic taiwan nation health insur databas use identifi cirrhot patient treatment nave hcc cm undergo rfa hospit januari decemb patient concurr histori cirrhot relat complic year year surviv rate cirrhot patient complic respect patient without complic p respect age hazard ratio hr confid interv ci p cirrhot relat complic hr ci p signific increas year mortal hr mortal patient complic compar without complic ci ci ci respect p cirrhot patient earli stage hcc undergo rfa poor liver reserv correl poor outcom presenc histori three cirrhot relat complic increas year mortal fold | D006528;D017115;D004932;D008113 | T191;T061;T047;T020 |
36,221,338 | efficaci phellinus linteus extract immun enhanc consort random doubl blind placebo control pilot trial immun major system defend human bodi outsid recent interest food relat immun increas | D003912;D015850 | T109;T116;T129 |
36,221,337 | import eosinophil infiltr colon mucosa ulcer coliti patient refractori mainten therapi prospect singl center studi eosinophil infiltr sometim observ histolog ulcer coliti uc effect degre infiltr treatment cours uc complet understood investig whether short term steroid administr uc patient refractori mainten therapi high eosinophil infiltr colon mucosa contribut clinic endoscop improv ten patient endoscop activ patholog high eosinophil infiltr base patholog examin use endoscop biopsi examin clinic background start steroid treatment clinic endoscop improv steroid use assess prospect averag initi steroid dosag durat use mg day respect mean valu steroid use clinic activ index mayo endoscop subscor uc endoscop index sever respect score improv signific steroid use p p p respect steroid discontinu patient patient requir steroid administr may case uc eosinophil infiltr colon mucosa resist mainten treatment suggest short term steroid administr may contribut clinic endoscop improv | D003093;D004802 | T047 |
36,221,336 | astrocytoma myelin oligodendrocyt glycoprotein antibodi associ encephalomyel case report demyelin similar malign clinic symptom magnet reson imag mri import auxiliari examin diagnosi demyelin diseas malign sinc mri symptom difficult distinguish demyelin malign auxiliari examin demyelin diseas specif antibodi play import role distinguish previous studi report demyelin diseas specif antibodi patient malign difficult confirm diagnosi malign tumor co occur demyelin diseas never report previous studi report diagnosi myelin oligodendrocyt glycoprotein antibodi associ encephalomyel mog em patient astrocytoma sever year | D001254;D003711;D004679 | T191;T047;T046 |
36,221,335 | chronic pain adult osteogenesi imperfecta relationship apprais cope qualiti life cross section studi chronic pain common experi osteogenesi imperfecta oi howev studi topic none emerg psycholog disciplin purpos work describ frequenc chronic pain characterist larg sampl adult oi well relationship clinic sociodemograph psycholog qualiti life variabl cross section studi carri sampl adult oi answer batteri onlin questionnair sociodemograph clinic variabl pain paramet particip apprais pain cope strategi interfer daili activ health relat qualiti life evalu descript correl analysi perform sampl report experienc pain frequent frequenc intens pain relat accumul fractur year p independ variabl like sever patholog use bisphosphon higher threat apprais pain associ increas perceiv pain intens interfer daili activ well decreas physic mental health p chronic pain frequent condit adult oi regardless sever patholog interfer usual activ impact qualiti life way particip apprais pain also influenc intens consequ intervent aim train strategi manag apprais pain could potenti improv adapt chronic pain | D059350;D010013 | T047;T184 |
36,221,334 | facial microbi flora beard versus nonbeard men oper room set singl center cross section strobe compliant observ studi beard controversi oper room set possibl retent shed pathogen surgic site infect pose signific burden healthcar system male healthcar worker enter oper room approach particip studi four facial swab sampl anonym collect hygien practic questionnair administ sampl taken upper lower lip sampl b cheek sampl c collect cm shed face coloni form unit cfus minimum inhibitori concentr mic meropenem resist determin sampl b random sampl b c addit meropenem resist isol cultur chlorohexidin sixti one beard nonbeard healthcar worker particip studi posit bacteri growth cfu rang cfuml bacteri growth signific higher beard particip p eighteen isol resist meropenem beard particip statist signific chlorohexidin effect inhibit growth strain includ meropenem resist isol beard men oper room signific higher facial bacteri load larger scale resist studi need address facial bacteri resist among healthcar worker oper room studi aim estim facial microbi load identifi strain antimicrobi resist profil beard versus nonbeard male healthcar worker oper room tertiari hospit middl east | D000890;D009873 | T121;T093;T073 |
36,221,333 | use machin learn investig role plastic surgeon anatom injuri retrospect observ studi plastic surgeon histor indispens reconstruct posttraumat defect role trauma center worldwid clear defin therefor aim investig contribut plastic surgeon trauma care use machin learn anatom injuri viewpoint conduct retrospect studi review data trauma patient hospit march februari total patient classifi duplic accord trauma relat depart conduct initi treatment evalu sever covari includ age sex caus trauma treatment outcom surgic data sever indic injuri sever score abbrevi injuri scale ai random forest algorithm use rank relev trauma relat depart categori ai outcom addit test chi squar test perform compar two group base whether patient receiv initi treatment trauma bay plastic surgeri depart ps group non ps group ai categori depart ps rank first face extern categori analyz relev trauma relat depart six categori ai random forest algorithm patient face categori ai ps group correl outcom except rate discharg home p upon verifi result use random forest found ps affect outcom extern categori ai patient ps group patient non ps group statist signific differ two group compar outcom ps contribut consider face extern region among six ai categori howev correl plastic surgic treatment outcom trauma patient investig plastic surgeon role base anatom injuri use machin learn first time field trauma care | D066231;D014193 | T093;T097;T073 |
36,221,332 | analysi predictor partial splenic embol thrombocytopenia liver cirrhosi blood transfus splenectomi partial splenic embol pse general perform thrombocytopenia patient cirrhosi recent thrombopoietin tpo agonist becom avail investig patient would benefit necessari therefor import understand fluctuat cytokin level associ pse therefor fluctuat platelet associ immunoglobulin g paigg interleukin il tpo level pse analyz studi studi includ patient liver cirrhosi thrombocytopenia aim improv platelet count fluctuat paigg il tpo level investig averag splenic embol ratio patient pse platelet count rose signific ml ml p il rose signific pgml pgml p tpo rose signific fmolml fmolml p paigg decreas signific ng cell ng cell p multivari analysi factor relat rate platelet increas pse primari biliari cholang b p splenic embol ratio b p il chang ratio b p paigg chang ratio b p signific attempt improv thrombocytopenia pse adequ splenic embol need obtain togeth improv il paigg tpo level unsatisfactori improv thrombocytopenia tpo agonist administr consid | D004621;D013921 | T061;T047 |
36,221,331 | gene variant desmin rs may protect combin cancer cardiovascular death tamper adult popul cardiovascular risk studi desmin contain intermedi filament part muscl cytoskeleton previous report wild type cytosinecytosin genotyp common desmin synonym singl nucleotid polymorph c rs associ cardiovascular diseas cohort subject tamper adult popul cardiovascular risk studi examin whether rs also associ earli death follow cohort subject age age outcom death collect nation statist centr linkag disequilibrium analysi gene express correl rs done silico follow subject wild type cytosinecytosin genotyp higher incid cancer death odd ratio confid interv ci p combin death cardiovascular diseas cancer ci p hard acut cardiovascular diseas event earli myocardi infarct andor death ci p compar subject allel silico result linkag disequilibrium gene express analys show negat gene express size associ rs theoret decreas desmin express find suggest variat rs desmin may serv surrog marker variat involv decreas death combin cancer cardiovascular diseas | D002318;D009369 | T191;T047 |
36,221,330 | abnorm uterin posit pregnanc secondari abdomin surgeri two case report umbil cord way exchang gas suppli nutrient excret metabol thrombosi umbil cord lead fetal hypoxia jeopard fetal health caus fetal death umbil vessel thrombosi rare report difficult detect prenat | D011248;D013927 | T046 |
36,221,329 | new smokeless moxibust knee osteoarthr studi protocol multicent singl blind random control trial knee osteoarthr koa chronic inflammatori diseas high morbid disabl age obes popul increas medic servic diseas purpos studi compar clinic efficaci herbal activ carbon smokeless moxibust tradit moxibust treatment koa determin clinic efficaci herbal activ carbon smokeless moxibust treatment koa | D009071;D020370 | T061;T047 |
36,221,328 | factor associ preval malnutrit among adult hemodialyt patient two center studi jeddah region saudi arabia chronic kidney diseas one common diseas world character irrevers impair kidney metabol excretori endocrin function end stage renal diseas patient requir renal replac therapi hemodialysi hd protein energi wast common health problem among hd patient studi aim assess nutrit status hd patient two hd center jeddah saudi arabia determin associ factor cross section studi conduct two differ dialysi center jeddah saudi arabia femal male hd patient malnutrit recogn use modifi subject global assess sga compris two part medic histori physic examin sociodemograph health status patient also determin patient classifi base sga score two group normal malnourish overal particip show malnutrit unemploy low muscl strength mass high level medic use high dialysi vintag posit p associ malnutrit conclus sga score indic high preval malnutrit among hd patient result show import regular assess follow up hd patient ensur better health nutrit status | D007676;D044342 | T047 |
36,221,327 | comparison systemat random core transrect ultrasonographi guid prostat biopsi magnet reson imag transrect ultrasonographi fusion target prostat biopsi aim compar complic patholog outcom systemat core transrect ultrasonographi guid prostat biopsi trus pb magnet reson imag trus fusion target prostat biopsi mri trus ftpb examin patient underw prostat biopsi may decemb retrospect among patient underw core trus pb patient underw mri trus ftpb clinicopatholog featur complic group compar propens score match signific differ clinic featur complic rate group p multivari analys prostat volum shown signific predictor overal complic infecti complic bleed relat complic clavien dindo grade complic prostat biopsi p present studi demonstr safeti mri trus ftpb term complic compar trus pb although combin mri trus ftpb core trus pb provid enhanc diagnost power mri trus fgb alon could provid reason diagnost valu prostat cancer appar diffus coeffici suspici grade prostat cancer likert suspici grade prostat cancer appar diffus coeffici map multiparametr mri patient diagnos clinic signific prostat cancer cspca confirm cspca mri target core appar diffus coeffici suspici grade diagnos cspca confirm cspca mri target core | D053783;D011471 | T191;T060 |
36,221,326 | clinicopatholog prognost valu lncrnas express gastric cancer field synopsi observ studi databas valid purpos studi evalu exist evid field long non code rnas lncrnas prognosi gastric cancer | D062085;D013274 | T191;T123;T114 |
36,221,325 | standard enhanc adher counsel improv hiv viral suppress among children adolesc homa bay turkana counti kenya viral suppress suboptim among children adolesc antiretrovir therapi art kenya implement evalu standard enhanc adher counsel seac packag improv viral suppress children adolesc suspect treatment failur homa bay turkana seac packag implement februari septemb includ standard procedur operation enhanc adher counsel eac process provid train psychosoci support communic skill children live hiv caregiv mentorship provid peer educ eac process individu case manag enrol children adolesc age year suspect treatment failur viral load vl copiesml receiv eac standard well receiv seac pre post evalu seac packag conduct high volum facil pre post standard comparison perform use wilcoxon mann whitney pearson chi squar test level signific multivari logist regress perform identifi factor associ viral resuppress studi enrol particip pre post seac implement post seac particip attend least eac session n pre seac client record eac attend time eac follow detect high vl reduc median day interquartil rang iqr iqr day pre versus post seac p time complet least session reduc median day iqr iqr day pre versus post seac p greater percentag client complet recommend minimum eac session post seac n versus n pre seac p among particip repeat vl within month follow high vl seac increas viral suppress n n p implement seac packag signific reduc time initi eac time complet least eac session signific associ viral suppress children adolesc suspect treatment failur | D019380;D015658 | T121;T047 |
36,221,324 | systemat review tuina cervic hypertens protocol systemat review meta analysi cervic hypertens secondari form hypertens high incid rate main etiolog cervic hypertens relat cervic spondylosi common use antihypertens drug poor efficaci treatment cervic spondylosi improv symptom cervic spondylosi effect reduc blood pressur massag effect improv symptom patient cervic hypertens systemat review massag treatment cervic hypertens studi aim evalu efficaci safeti massag patient cervic hypertens | D006973;D055009 | T047 |
36,221,303 | normal lark deviant owl relationship chronotyp complianc covid mitig measur current evid suggest prevent measur social distanc wear face mask critic contain spread covid recent burgeon literatur empir examin wide rang facet level person individu differ variabl associ peopl adher covid regul howev lack direct evid regard role chronotyp complianc pandem safeti measur accord evening epidemiolog liabil hypothesi peopl later chronotyp like breach covid restrict despit hypothesi shed consider light potenti role chronotyp abid virus mitig measur rigor test use empir data fill gap present research investig link morning evening complianc covid contain polici chines sampl two studi use multipl popul student communiti adult divers measur adher public health guidelin self report actual behavior consist show individu orient toward morning display higher level complianc covid prevent peopl orient toward evening overal find present first empir confirm evening epidemiolog liabil hypothesi highlight role chronotyp adher covid prevent guidelin | D000086382;D020305 | T012;T047;T067 |
36,221,294 | express profil function analysi plasma exosom circular rnas acut myocardi infarct acut myocardi infarct ami common cardiovascular diseas high rate morbid mortal global dysregul circular rnas circrna shown close relat various patholog aspect ami howev function exosom circrna ami yet investig purpos studi investig express profil plasma exosom circrna ami explor potenti function express profil plasma exosom circrna patient ami stabl coronari heart atherosclerot diseas cad healthi control obtain geo express dataset gse also analyz bioinformat function potenti pathway interact network relat microrna associ differenti express circrna total exosom circrna regul exosom circrna regul identifi differenti express control group ami cad patient respect compar cad group differ exosom circrna regul identifi ami group function analysi suggest parent gene exosom hascirc signific enrich biolog process lysin degrad pathway interact network analysi indic exosom hascirc associ mir mir mir mir may play role pathogenesi ami mapk signal pathway studi identifi differenti express function exosom circrna ami provid understand potenti pathogenesi exosom circrna relat compet endogen rna cerna network ami | D035683;D009203 | T047;T123;T114 |
36,221,252 | longitudin investig execut function develop employ task base teacher report fnir multimethodolog year old children increas focus rest state function connect rsfc use access function near infrar spectroscopi fnir advanc knowledg interconnect natur neural substrat under execut function ef develop adult clinic popul less known relationship rsfc development chang ef preschool year typic develop children gap present studi address employ task base assess teacher report fnir multimethodolog preregist studi contribut understand neural basi ef develop longitudin children age chang prefront cortex pfc rsfc util fnir ef measur common task base assess day night task teacher report behavior brief p monitor multipl timepoint initi assess h follow month follow month follow measur rsfc strong correl h apart provid evid high rsfc measur reliabl use fnir preschool age children pfc rsfc posit correl perform task base report base ef assess children pfc function connect rest uniqu predict later ef control verbal iq age sex function connect rest use fnir may potenti show rapid chang ef develop young children neurophysiolog also correl task base ef perform ecolog relev teacher report ef classroom context | D056344;D019265 | T059;T041 |
36,221,250 | effect physiotherapi rehabilit qualiti life patient hospit covid review find key studi publish estim percentag individu covid due infect sar cov need hospit most increas proport age reach almost older year among hospit patient one fifth requir treatment intens care unit icu due acut respiratori distress syndrom multiorgan failur hypoxem respiratori insuffici patient moder sever covid hospit earli stage pandem continu hospit report fatigu muscl weak joint stiff reduc mobil increas risk fall impair qualiti life physiotherapi recogn import rehabilit covid patient requir hospit current physiotherapi guidelin recommend individu covid includ treatment method outcom measur evalu effect respiratori physic function qualiti life establish pre covid era avail extant scientif literatur main report effect physiotherapi patient covid acut hospit cours diseas lack qualiti primari experiment studi effect physiotherapi rehabilit post covid patient hospit review aim present updat effect physiotherapi rehabilit qualiti life patient hospit covid find key studi publish | D000086382 | T047;T067 |
36,221,248 | nonbiolog parent encount strateg resist asymmetri invalid genet gestat parent status among lgbtq parent lesbian gay bisexu transgend queer lgbtq famili expand understand count famili includ legal well chosen tie yet nonbiolog parent lgbtq famili vulner invalid erasur social institut includ health care legal educ set genet gestat linkag privileg current studi guid queer phenomenolog perspect examin lgbtq parent experi respond domin norm relat famili related membership thus queer famili mix method studi sampl lgbtq parent includ cisgend women transnonbinari particip examin question way genet asymmetri matter famili qualit quantit analys yield three primari find reveal experi erasur discrimin well proactiv strategi activ resist use counteract difficulti theme organ encount margin invalid health care school beyond b strateg action discurs practic toward parent equal c confront resist need legal symbol parent strategi studi document way nonbiolog lgbtq parent particular embrac resist societ norm biolog connected implic nurs profession includ find reproduct perinat context particular site invalid necessit educ rang queer nonbiolog transnonbinari parent parent includ profession health care encount | D000072339 | T098 |
36,221,242 | patient treat fluoroscopi guid caudal epidur inject lumbar disc herniat present experi discuss complic assess earli vs long term outcom fluoroscopi guid caudal epidur inject lumbar disc herniat ldh | D007405 | T047 |
36,221,241 | predict prognosi outcom patient pulmonari embol emerg depart use earli warn score qsofa score determin predict abil nation earli warn score news nation earli warn score news quick sequenti organ failur assess qsofa score prognosi pulmonari embol pe emerg depart | D000080162;D011655;D018805 | T046;T047;T058 |
36,221,239 | metastat lung adenocarcinoma unusu present focal neurolog deficit background sudden focal neurolog deficit high index suspicion stroke crucial investig potenti under caus sudden neurolog deficit emerg depart ed enhanc better recognit proper care case report year old man present ed left side weak headach week durat ischem stroke preliminarili diagnosi ed brain comput tomographi ct show abnorm right pariet lobe chest x ray show right lung opac suggest mass right upper lobe lung subsequ malign suspect brain magnet reson imag mri show lesion right tempor right pariet region ct scan chest abdomen pelvi order identifi primari sourc malign multipl nodul within lung liver found biopsi taken nodul sent patholog laboratori final impress made result primari lung adenocarcinoma brain liver metastasi patient refer palliat care team oncolog team malign workup get proper attent conclus hypodens area ctmri unilater weak headach necessarili mean under stroke howev repres brain metastasi case report aim increas awar hypodens brain could repres brain metastasi necessarili simpl ischem stroke therefor workup done avoid miss diagnos approach differ | D000077192;D001932;D000083242;D008175;D020521 | T191;T047 |
36,221,235 | cognit impair peopl physic frailti use phenotyp model systemat review meta analysi perform systemat review meta analysi studi relationship cognit function phenotyp frailti status | D060825;D000073496 | T046;T184;T048;T033 |
36,221,222 | potenti micro flow lc msms proteom due excel sensit nano flow liquid chromatographi tandem mass spectrometri lc msms mainstay proteom research howev come expens limit throughput robust contrast micro flow lc msms enabl high throughput robust quantit reproduc precis retain moder degre sensit featur make attract technolog wide rang proteom applic particular larg scale project involv analysi hundr thousand sampl | D040901;D020543 | T091;T123;T116 |
36,221,213 | pinpoint accuraci guid core biopsi diagnost accuraci musculoskelet lesion core biopsi integr work diagnosi musculoskelet lesion prior referr christchurch hospit tertiari referr centr sarcomasmusculoskelet lesion mani patient undertak guid core biopsi peripher hospit wish assess accuraci biopsi undertaken peripher centr compar done tertiari set | D062005;D001859;D061705 | T191;T060 |
36,221,212 | overnight joint replac surgeri pilot australian studi stretch healthcar system elect surgeri backlog measur improv effici decreas cost associ surgic procedur need priorit studi compar benefit multi disciplinari involv enhanc recoveri surgeri era protocol led overnight model follow total hip replac thr total knee replac tkr | D019644;D019645 | T061 |
36,221,204 | readabl onlin patient educ materi common orthopaed paediatr condit within australasia role patient educ materi paediatr patient increas read grade level eighth grade usa year nine australia new zealand recommend accept aim paper assess read grade level paediatr onlin patient educ materi within australasia | D001170;D057220;D009140;D009985 | T091;T047;T041 |
36,221,201 | laparoscop versus open inguin hernia repair infant initi experi inguin hernia repair common oper perform children australia open repair continu prefer method treatment infant despit laparoscop repair lr gain popular amongst intern centr aim analys initi outcom lr paediatr centr | D018681;D006552;D010535;D006848 | T047;T019;T061;T060;T121;T190 |
36,221,190 | routin patholog evalu circular stapler anastomot ring use resect colorect cancer retrospect studi systemat review meta analysi circular stapler common use reconstruct radic resect colorect cancer patholog analysi anastomot ring common practic although benefit unclear purpos studi evalu use routin histopatholog analysi anastomot ring origin seri systemat review literatur | D015179;D017792 | T191;T061 |
36,221,189 | effect background music stress oper surgeon scope review despit ubiquit sound music play oper theatr ot around world effect music intraop clinician stress ill defin present scope review aim map avail evid effect background music ot experi stress oper surgeon | D009146;D066231 | T170;T097 |
36,221,187 | effect ozon versus naringin testicular injuri experiment induc ulcer coliti adult male albino rat testicular dysfunct caus continu inflamm oxid stress present local site ulcer coliti uc spread test via system circul influenc ozon naringin coliti mediat testicular dysfunct investig studi forti eight adult male rat divid four group control group ii dextran sodium sulfat dss uc induc group iii dssnaringin iv dssozon group uc induc group ii iii iv use ml dss drink water per day day gastric gavag anim sacrif day start blood sampl obtain estim serum testosteron hormon testicular tissu process measur tissu malondialdehyd mda examin light electron microscop ultrastructur group ii reveal relat thick basement membran envelop seminifer tubul sertoli cell cytoplasm appear rarifi wide intracellular space vacuol multipl lysosom distort spermatogonia electron dens nuclei cytoplasm primari spermatocyt small nuclei electron dens cytoplasm abnorm sperm profil visibl middl piec mid principl end piec mark affect disorgan axonem outer dens fiber leydig cell reveal dilat cisterna smooth endoplasm reticulum morphometr statist analys perform group iii show improv howev group iv show improv result indic ozon caus mark improv naringin uc induc testicular damag via antioxid anti inflammatori properti | D003093;D060766;D010126 | T103;T047;T167 |
36,221,183 | discoveri potent otubusp dual inhibitor target proteostasi non small cell lung cancer deubiquitin enzym dub key regulatori compon ubiquitin system mani dub reveal play key role normal physiolog diseas howev limit dub member well character inhibitor otub usp two dub report promot immun evas tumorigenesi tumor model yet target inhibitor earli stage develop describ lead identif optim otubusp dual inhibitor exhibit high potent select inhibit target subnanomolar ic vitro inhibit dub phenocopi doubl knockdown otubusp exert pronounc antiprolif effect h non small cell lung cancer nsclc cell line moreov efficaci mitig tumor growth vivo collect result provid use tool pharmacolog perturb otubusp introduc promis therapeut strategi dual dub inhibit treat nsclc | D002289;D008175 | T191 |
36,221,178 | spectral imag normal hydrat desicc porcin skin use polar light significancespectroscop structur imag tissu layer import investig tissu health howev investig superfici tissu difficult use optic imag due convolv absorpt backscatt light deeper layersaimthi report investig effect hydrat desicc ex vivo porcin skin reflect polar light differ wavelength light emit diod approachw develop spectroscop polar imag system investig submicron chang tissu structur separ polar depolar backscatt light submicron structur chang subsurfac deeper tissu layer separ monitoredresultsth result demonstr polar light reflect consist scatter event averag littl wavelength depend reflect polar light increas hydrat lead modest increas total reflect wherea desicc littl effect howev hydrat affect polar reflect desicc slight lower polar reflectanceconclusionshigh scatter reticular dermi like due swell collagen fiber bundl dermal layer increas fibril space epiderm skin surfac show littl chang due stratum corneum resist desicc maintain hydrat | D004817;D012867 | T022;T024 |
36,221,173 | detect differenti semi transpar materi simul biolog structur use optic coher tomographi phantom studi significancelymphat peripher nervous system imag prime import monitor various import patholog process includ cancer develop metastasi respons therapyaimopt coher tomographi oct promis approach imag task challeng near transpar natur structur aim detect differenti semi transpar materi use oct textur analysi toward label free neurographi lymphographyapproachw recent demonstr innov oct textur analysi base approach use speckl statist imag lymphat nerv vivo reli negat contrast howev two near transpar structur could easili differenti textur analysi paramet space perform rigor follow studi improv upon differenti control phantom mimick optic properti tissuesresultsth result three paramet rayleigh distribut fit oct imag six type tissu mimick materi vari transpar biophys properti demonstr clear differ suggest rout improv lymphat nerv differentiationconclusionsw demonstr novel oct textur analysi base lymphat nerv differenti methodolog tissu simul phantom futur work focus longitudin vivo lymphangiographi neurographi respons cancer therapeut toward adapt person medicin | D042601;D041623 | T023;T060 |
36,221,152 | effect mind base intervent fatigu psycholog wellb women cancer systemat review meta analysi randomis control trial cancer diagnosi treatment caus fatigu stress anxieti detriment effect patient famili wider communiti mind base intervent appear posit effect manag cancer relat symptom | D064866;D009369 | T191;T041 |
36,221,151 | efficaci azithromycin prevent exacerb non cystic fibrosi bronchiectasi meta analysi random control studi efficaci azithromycin prevent exacerb non cystic fibrosi bronchiectasi remain controversi conduct meta analysi explor influenc azithromycin versus placebo treatment non cystic fibrosi bronchiectasi | D017963;D001987 | T047;T109;T195 |
36,221,150 | high dose intraven glucocorticoid induc hyperamylasemia case seri glucocorticoid mani side effect high dose intraven applic may caus rare advers reaction hyperamylasemia aim studi explor clinic characterist treatment prognosi hyperamylasemia induc high dose intraven glucocorticoid | D034321;D010195 | T047;T046 |
36,221,149 | intimin eae virul membran protein pagc gene associ biofilm format multidrug resist escherichia coli salmonella enterica isol calv diarrhea studi aim evalu associ intimin eae pagc gene biofilm format multidrug resist mdr phenotyp escherichia coli salmonella enterica collect calv diarrhea | D004927;D019779 | T007;T047 |
36,221,146 | function capac communiti dwell older adult maintain higher friend network famili network implic two year longitudin studi maintain level function capac essenti healthi age research associ chang level function capac social network typolog explor two year period particip recruit communiti base cohort studi within kashiwa citi japan data year use cognit function function capac social network typolog assess use mini mental state examin japan scienc technolog agenc index compet lubben social network scale respect binomi logist regress analysi conduct evalu associ individu person network function capac | D033062;D057187 | T098;T054;T056 |
36,221,144 | tau seed case multipl sclerosi relaps remit multipl sclerosi ms inflammatori demyelin disord central nervous system mani case lead progress ms neurodegen diseas progress ms untreat relentless caus unknown prior studi ms document neuron accumul phosphoryl tau protein character anoth heterogen group neurogen disord tauopathi known caus tauopathi myriad includ point mutat within tau gene amyloid beta accumul repeat head trauma viral infect other propos tau essenti featur prion form intracellular assembl exit cell enter secondari cell serv templat replic process term seed previous develop special biosensor cell system detect quantifi tau seed brain tissu hypothes progress ms tauopathi potenti trigger inflamm test detect tau seed frozen brain tissu subject multipl sclerosi evalu multipl brain region singl subject detail clinic histori observ seed outsid ms plaqu enrich immunopurif two anti tau antibodi hj md immunohistochemistri md confirm prior report tau accumul ms although larger studi requir data suggest progress ms may consid secondari tauopathi | D009103;D019636;D011328;D024801 | T047;T116;T005 |
36,221,141 | digit detect dementia studi protocol pragmat cluster random trial examin applic patient report outcom passiv clinic decis support system earli detect alzheim diseas relat dementia adrd primari care set challeng due time constraint stigma implement scalabl sustain patient driven process may improv earli detect adrd howev compet approach inform may obtain either direct patient eg questionnair passiv use electron health record ehr data studi aim identifi benefit combin approach use pragmat cluster random clinic trial | D000544;D020000 | T047;T058;T170;T048 |
36,221,140 | impact nation hepat b immun program china model studi elimin hepat b virus hbv strike challeng countri high moder diseas burden therefor use china practic case share experi similar countri may acceler achiev target reduct hbv relat incid aim evalu impact nation hbv immun strategi china feasibl achiev target differ scenario | D006509;D017325;D017589 | T047;T116;T058;T121;T129 |
36,221,136 | pca outperform popular hidden variabl infer method molecular qtl map estim account hidden variabl wide practic import step molecular quantit trait locus molecular qtl henceforth qtl analysi improv power qtl identif howev benchmark studi perform evalu efficaci various method develop purpos | D008957;D040641 | T170;T028 |
36,221,134 | corpus luteum hemorrhag acquir hemophilia case report literatur review ruptur corpus luteum cl may occur stage woman reproduct life bleed ruptur cl vari self limit hemorrhag massiv hemoperitoneum caus shock subsequ emerg surgeri hemoperitoneum secondari ruptur cl rare complic situat women bleed disord | D006467;D006490 | T121;T047 |
36,221,133 | glyphos exposur earli pregnanc reduc fetal growth prospect observ studi high risk pregnanc prenat glyphos gli exposur associ advers reproduct outcom anim studi littl known effect gli exposur pregnanc human popul studi aim establish baselin urin gli level high risk racial divers pregnanc cohort assess relationship prenat gli exposur fetal develop birth outcom | D047109;D018566 | T038;T046;T039 |
36,221,132 | identif risk factor incid cervic insuffici nullipar parous women popul base case control studi cervic insuffici one under caus late miscarriag preterm birth although mani risk factor identifi relat magnitud associ risk nullipar versus parous women well demonstr especi incid cervic insuffici ici aim studi investig compar magnitud associ ici predict factor nullipar parous women investig various aspect obstetr histori parous women | D000022;D007232;D047928 | T047;T046;T033 |
36,221,131 | foxp gene regul lung function product matrix metalloproteinas inflammatori mediat viabil lung epithelia gene involv lung develop may becom dysregul adult life contribut pathogenesi lung diseas multipl gene regul lung develop includ forkhead box protein p foxp | D054990;D029424 | T047 |
36,221,130 | efficaci split thick skin graft combin novel sheet type reprocess micron acellular dermal matrix autolog split thick skin graft stsgs remain mainstay treatment larg skin defect despit mani advantag exist critic disadvantag unfavor scar graft contractur addit use structur tendon bone expos overcom limit acellular dermal matrix adm wide use stsg cgderm matrix recent develop novel reprocess micron adm rmadm studi outcom combin applic rmadm stsg full thick wound analyz | D062088;D003286;D017719 | T047;T024;T190 |
36,221,128 | investig neomycin biodegrad condit use ericoid mycorrhiz white rot fungal speci search method biodegrad recalcitr compound use saprotroph fungi white rot fungi particular belong phylum basidiomycota gain interest group fungi possess batteri unspecif extracellular enzym util biodegrad prefer phenol compound work investig condit white rot fungus tramet versicolor ericoid mycorrhiz fungus rhizoscyphus erica belong phylum ascomycota could use biodegrad antibiot aminoglycosid neomycin co metabol condit extern nutrient suppli furthermor also investig whether biodegrad could accomplish use neomycin sole nutrient | D038821 | T004 |
36,221,127 | postnat development trajectori sex bias gene express mous pituitari gland pituitari gland regul essenti physiolog process growth pubert onset stress respons metabol reproduct lactat sex bias function hormon product describ under ident tempor deploy cell type specif sex bias pituitari gene regulatori network fulli understood | D035683;D010902 | T023;T123;T114 |
36,221,126 | reliabl valid japanes treatment self regul questionnair japanes worker motiv intervent use prevent measur occup health howev exist studi primarili focus motiv method stage motiv process extrins intrins motiv treatment self regul questionnair tsrq predict worker health motiv stage accord studi examin reliabl valid japanes version tsrq diet exercis occup health set | D000068356 | T055 |
36,221,125 | adenosin receptor agonist reduc mmp express healthi like macrophag macrophag ankylos spondyl patient ankylos spondyl inflammatori autoimmun diseas most affect differ joint bodi macrophag predomin cell mediat diseas progress secret sever pro inflammatori mediat differ receptor involv macrophag function includ adenosin receptor ar main object studi assess effect appli adenosin receptor agonist cgs gene express inflammatori mediat includ bone morphogenet protein bmp matrix metalloproteinas mmp macrophag patient compar healthi macrophag | D013167 | T047 |
36,221,123 | improv cancer immunotherapi ration combin oncolyt virus modul target key signal pathway oncolyt virus ov repres new class multi modal immunotherapi cancer ov elicit antitumor immun key overal therapeut efficaci current clinic effect ov monotherapi remain limit thus investig explor various combin anti cancer agent demonstr improv therapeut efficaci cancer cell evolv alter key signal pathway enhanc cell prolifer cancer progress metastasi cellular molecular chang offer promis target ration cancer therapi design regard key molecul relev signal pathway cancer cell orand immun cell egfr kras eg kras gc pik akt mtor erk mek jak stat p pd pd l epigenet immun pathway eg histon deacetylas cgas sting current investig potenti synerg ov modul immun milieu tumor microenviron tme therebi improv sustain antitumor immun mani small molecul modul signal pathway develop shown strong therapeut potenti review key find relat ov mediat immunotherapi util small molecul modul signal pathway immuno oncolog focus discuss rational potenti strategi combin ov select modul target key cellular signal pathway cancer orand immun cell modul tme enhanc antitumor immun therapeut efficaci final provid perspect viewpoint applic novel experiment system technolog propel excit branch medicin bright futur | D009369;D050130;D050504 | T191;T061;T005 |
36,221,121 | microrna negat regul osteogen differenti periodont ligament deriv cell direct target growth factor receptor microrna mirna accept critic regul cell differenti howev whether microrna mir could affect osteogen differenti periodont ligament pdl deriv cell still unknown aim studi explor mechan under role mir osteogenesi pdl deriv cell periodont | D035683;D010518 | T047;T123;T114 |
36,221,120 | effect virtual realiti erotica ejacul qualiti sperm donor balanc random control cross within subject trial previous research shown type durat erot materi men access masturb influenc semen paramet knowledg use virtual realiti vr headset present erotica previous studi reason vr provid immers experi user semen paramet masturbatori ejacul may alter | D012661;D000076142 | T066;T031 |
36,221,119 | cspg express soft tissu sarcoma associ poor prognosi low cytotox immun respons soft tissu sarcoma sts heterogen pro metastat tumor identif accur prognost factor novel therapeut target crucial cspg cell surfac proteoglycan oncogen function recent emerg potenti target immunotherapi includ cell therapi base cspg specif chimer antigen receptor car redirect cytokin induc killer lymphocyt cspg carcik sts howev express cspg poor known sts far | D000970;D000076962;D012509;D012983 | T116;T192;T121;T191;T109;T129 |
36,221,118 | cross watersh distribut pattern challeng elimin oncomelania hupensi intermedi host schistosoma japonica sichuan provinc china snail control critic schistosomiasi control effort china howev emerg oncomelania hupensi challeng achiev schistosomiasi control present studi aim test whether amphibi snail spread across watersh use combin popul genet geograph statist | D049851;D012552 | T047;T204 |
36,221,116 | systemat descript interdisciplinari multimod pain treatment programm patient chronic musculoskelet pain use tidier checklist provid thorough systemat descript interdisciplinari multimod pain treatment programm impt patient chronic musculoskelet pain cmp use tidier checklist guid | D064869;D059350;D059352 | T061;T047;T184;T033 |
36,221,115 | hydroxymethyl alter cell free dna reflect molecular distinct diffus larg b cell lymphoma differ primari site hydroxymethylcytosin hmc import dna epigenet modif play vital role tumorigenesi progress prognosi mani cancer diffus larg b cell lymphoma dlbcl involv almost organ prognosi patient dlbcl differ primari site vari great previous studi shown hmc display tissu specif atlas role dlbcls differ primari site remain unknown | D000073888;D016543;D016403 | T191;T123;T114 |
36,221,111 | world first digit cell twin cancer electrophysiolog digit revolut cancer research introduct function silico model addit vivo tumor model open new unlimit possibl cancer research drug develop world first digit twin cell electrophysiolog human lung adenocarcinoma unveil enabl investig evalu new research hypothes modul function ion channel cell membran import better understand cancer develop progress well develop new drug predict treatment | D000077192;D008175 | T191 |
36,221,110 | pandem relat socioeconom disrupt advers health outcom cross section studi femal caregiv covid pandem effort mitig transmiss result sudden widespread socioeconom disrupt includ school child care closur unemploy underemploy hous precar understand extent disrupt may contribut advers health outcom critic establish polici prioriti mitig harm | D000086382;D058873 | T047;T067 |
36,221,109 | rendezv ambul prehospit physician capit region denmark descript studi two tier emerg medic servic respons system ambul physician staf rapid respons vehicl unit ideal dispatch simultan physician need howev advanc resourc dispatch secondarili meet point rendezv establish reduc time advanc care studi aim assess extent rendezv task patient group involv physician contribut rendezv activ primari ambul rapid respons vehicl capit region denmark | D004632;D010820 | T061;T093;T058;T097 |
36,221,108 | eat behaviour among adolesc young adult seek obes treatment differ depend sex bodi composit parent countri birth adolesc young adult around world experi high rate weight gain under eat behaviour may lead overconsumpt energi complex depend number factor aim studi explor eat behaviour among adolesc young adult refer special obes treatment differ depend sex bodi composit parent countri birth | D001823;D005247 | T055;T040;T032 |
36,221,107 | manag cluster effect learn effect design analysi randomis surgic trial review exist guidanc complex associ deliv randomis surgic trial cluster effect centr surgeon surgic learn well known despit approach use manag complex opinion vari guidanc document develop support clinic trial design report work aim identifi examin exist guidanc consid relev cluster effect learn curv within surgic trial | D007858 | T061;T041;T062 |
36,221,106 | leukocyt telomer length allel variat relat gene risk coronari heart diseas peopl long stand type diabet type diabet associ acceler vascular age advanc atherosclerosi result increas rate cardiovascular diseas prematur death evalu associ leukocyt telomer length ltl allel variat snps ltl relat gene incid coronari heart diseas chd adult long stand type diabet | D003327;D003922;D009203 | T047 |
36,221,105 | exosom mediat regul phenotyp transit vascular smooth muscl cell atherosclerosi cardiovascular diseas one lead caus human mortal worldwid main due atherosclerosi phenotyp transit vascular smooth muscl cell vsmcs key event develop exosom contain varieti specif nucleic acid protein mediat intercellular communic role exosom attract attent review use vsmc phenotyp transit entri point introduc effect exosom differ perspect discuss status quo defici potenti futur direct field provid new idea clinic research treatment video abstract | D050197;D055354;D009696 | T047;T046;T026;T123;T114 |
36,221,104 | neuregulin attenu diabet cardiomyopathi regul autophagi via ampkmtor signal pathway diabet cardiomyopathi character left ventricl dysfunct cardiomyocyt apoptosi interstiti fibrosi serious complic diabet mellitus dm autophagi mechan essenti maintain normal heart morpholog function dysregul produc patholog effect diabet heart neuregulin nrg adipokin exert protect effect metabol disord insulin resist aim studi explor whether nrg could amelior dm induc myocardi injuri regul autophagi | D003921;D003922;D058065 | T050;T047 |
36,221,102 | pmm cdg caus av mutat associ heterozyg kilobas delet case report congenit disord glycosyl cdg larg group inborn error metabol differ cdg type report date first character pmm cdg autosom recess transmiss also frequent pmm gene encod phosphomannomutas novel genet variat caus pmm cdg report case present report case french child healthi unrel parent present congenit ataxia hypotonia hyperlax invert nippl well alter coagul paramet liver function transferrin isoelectrofocus reveal typic type cdg profil direct sanger sequenc quantit pcr pmm reveal uniqu novel genotyp one allel patient heterozygot known missens variant nm pmm cc palav exon second allel whole genom sequenc wgs indic presenc novel heterozyg kb delet | D018981 | T047 |
36,221,101 | polygen risk score trend new variant chromosom associ male gout genom wide associ studi gout high hereditari diseas carri well known risk variant develop gout attack even hyperuricemia status perform genom wide associ studi gwas polygen risk score prs analysi illustr new genet architectur gout asymptomat hyperuricemia ah | D006073;D033461 | T047 |
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