Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,324,277	ventil avoid among critic ill covid patient acut respiratori distress syndrom determin incid signific ventil avoid patient critic coronavirus diseas covid	D000086382;D012128	T047;T067
36,324,259	impact coronavirus diseas pandem ultrasound screen development dysplasia hip follow imag report southeastern turkey investig effect coronavirus diseas restrict ultrasound us screen development dysplasia hip ddh children hospit	D006618;D000086382;D000082602	T019;T047;T067
36,324,258	n methyladenosin reader ythdf regul melanoma metastasi via executorloxl number studi demonstr n methyladenosin play vital role patholog process various tumour recent found writer eras affect tumourigenesi melanoma howev relationship reader yth domain famili ythdf protein melanoma still elus	D016601;D008545	T123;T191;T116
36,324,254	success extracorpor membran oxygen patient central airway obstruct due endotrach mass extracorpor membran oxygen ecmo assist blood circul gas exchang via heart lung machin ecmo use main intens care unit bridg therapi heart respiratori failur address transplant perform ecmo sometim use surgeri general anaesthesia depend patient under diseas natur oper oxygen suppli carbon dioxid remov capac limit venoven vv ecmo help describ use vv ecmo surgic resect endotrach mass rigid bronchoscopi patient develop decompens dyspnoea due central airway obstruct cao	D015199;D000402;D012131	T061;T047;T046
36,324,250	ultrastructur morpholog characterist anterior cruciat ligament pig studi use tesla diffus tensor imag diffus tensor imag research anterior cruciat ligament acl limit studi reveal acl fibrous microstructur tesla magnet reson imag therefor use magnet reson imag assess acl	D016118;D056324	T060;T023
36,324,246	associ nadir hematocrit sever acut kidney injuri pump coronari arteri bypass graft surgeri retrospect cohort studi base mimic iv databas background aim evalu associ postop nadir hematocrit hct sever acut kidney injuri aki patient undergo pump coronari arteri bypass graft opcabg surgeri materi method data patient receiv opcabg extract medic inform mart intens care iv mimic iv databas general addit model appli explor relationship nadir hct sever aki patient divid group quartil postop nadir hct lowest group hct refer conduct multivari logist regress model calcul adjust odd ratio ci evalu trend among group result total opcabg patient includ nonlinear associ nadir hct sever aki identifi adjust potenti confound nadir hct negat associ risk sever aki hct less statist signific highest hct group hct control group hct test trend signific p subgroup analys show increas postop nadir hct associ decreas risk sever aki p lower bmi group kgm conclus associ postop nadir hct sever aki patient opcabg nonlinear lower nadir hct may associ increas risk sever aki hct valu less howev statist signific found highest hct group control group	D047549;D058186	T061;T047;T037
36,324,242	recurr gastrointestin bleed due small bowel vascular malform patient turner syndrom diagnos surgic assist push enteroscopi background obscur gastrointestin bleed account approxim case gastrointestin bleed frequent site small bowel turner syndrom ts genet disord second x chromosom femal associ gastrointestin vascular malform turner syndrom describ case report vascular malform turner syndrom vari asymptomat sever recurr gi bleed data diagnosi manag patient lack case report year old girl ts present recurr symptomat melena initi work includ negat upper endoscopi negat bidirect endoscopi video capsul endoscopi vce demonstr larg amount blood small erythemat lesion small bowel without activ bleed negat meckel scan ct angiographi remark promin left lower mesenter blood vessel singl balloon enteroscopi demonstr promin vasculatur throughout small bowel clip place site question bleed patient underw surgic assist push enteroscopi due recurr bleed find consist diffus vascular malform start tranexam acid later transit estrogen therapi without report gi bleed anemia advers effect treatment month initi present conclus small bowel bleed life threat evid base guidelin children need turner syndrom associ gastrointestin vascular malform suspicion diagnosi high patient present gastrointestin bleed estrogen might effect therapi ts adolesc patient set diffus vascular malform dvm	D014424;D053704;D054079;D014652	T060;T047;T190
36,324,241	lung hamartoma resembl lung cancer report three case pulmonari hamartoma benign lung tumor howev difficult distinguish lesion diseas via imag three patient patholog confirm pulmonari hamartoma depart analyz believ necessari combin imag patholog clinic test individu patient assess enabl earlier definit diagnosi pulmonari hamartoma therefor necessari analyz summar clinic manifest imag featur patient pulmonari hamartoma improv earli recognit diseas clinician	D006222;D008175	T191
36,324,239	healthi context paradox reduc bulli come cost certain victim bulli remain one serious problem affect school system around world negat consequ bulli short long term wide document show victim student greater risk suffer psychosoci distress paper first summar current situat bulli prevent adopt contextu perspect briefli highlight characterist effect prevent program second address disturb phenomenon detect classroom bulli reduc intervent term healthi context paradox healthier context student remain situat victim found present poorer psycholog adjust intervent understand caus phenomenon may offer clue prevent bulli regard present three hypothes recent propos explain phenomenon final offer implic studi prevent bulli deriv healthi context paradox	D058445;D019548	T068;T098;T048
36,324,188	longitudin correl fruit veget consumpt depress symptom among middl age older adult south africa fruit veget intak may influenc mental well aim studi assess longitudin associ fruit veget intak depress symptom among rural south african	D014675;D005638	T168;T002
36,324,187	phosphodiesteras pdea novel target suppress catenin ras signal epitheli ovarian cancer lead theori ovarian carcinogenesi propos inflamm associ incess ovul driver oncogenesi consist theori nonsteroid anti inflammatori drug nsaid exert promis chemoprevent activ ovarian cancer unfortun toxic associ long term use nsaid due cyclooxygenas cox inhibitori activ previous studi suggest antineoplast activ nsaid cox independ rather may exert phosphodiesteras pde inhibit pdes repres uniqu chemoprevent target ovarian cancer given ovul regul cyclic nucleotid signal evalu pdea novel therapeut target ovarian cancer analysi cancer genom atlas tcga ovarian tumor reveal pdea overexpress associ signific wors overal surviv patient pdea express also posit correl upregul oncogen inflammatori signal pathway use small molecul inhibitor pf novel nsaid deriv pdea inhibitor mci show pdea inhibit lead decreas ovarian cancer cell growth induc cell cycl arrest apoptosi demonstr pro apoptot properti occur pka pkg signal use specif inhibitor block activ pdea genet knockout ovarian cancer cell crispca edit lead decreas cell prolifer coloni format migrat invas vivo tumor growth also demonstr pdea inhibit lead decreas wnt induc catenin nuclear transloc well decreas egf mediat activ rasmapk akt pathway ovarian cancer cell find implic pdea novel target ovarian cancer chemoprevent treatment	D051176;D010051	T123;T191;T116
36,324,186	trend evolut triatomini tribe hemiptera triatomina reproduct incompat four speci geniculatus clade geniculatus clade compos rufotuberculatus lignarius geniculatus megistus group relat evolutionarili speci genus panstrongylus nesotriatoma sever studi shown triatomin hybrid play import role transmiss chaga diseas natur hybrid speci geniculatus clade never report knowledg thus carri experiment cross speci geniculatus clade help elucid taxonom issu well contribut epidemiolog knowledg group	D014225;D010203;D014355	T047;T204
36,324,182	import caf cancer resist target therapi last two decad clinic oncolog revolution advent target drug howev efficaci therapi signific limit primari acquir resist reli cell autonom mechan also tumor microenviron cue cancer associ fibroblast caf extrem plastic cell tumor microenviron produc extracellular matrix compon build structur tumor stroma also releas growth factor chemokin exosom metabolit affect tumor properti includ respons drug treatment contribut caf tumor progress deepli investig review sever work howev role resist anticanc therapi particular molecular therapi larg overlook review specif dissect role caf drive resist target therapi discuss novel caf target therapeut strategi improv patient surviv	D000072645;D009369;D055354	T026;T191;T025
36,324,178	util health belief model comprehend diarrheal diseas dynam case cryptosporidiosi uganda diarrheal diseas contribut great report global childhood mortal morbid relat social econom consequ studi conduct analyz util health belief model hbm theori comprehend diarrheal diseas dynam uganda	D003457	T047
36,324,177	remnant cholesterol risk cardiovascular diseas type diabet nationwid longitudin cohort studi elev remnant cholesterol remnant c consid risk factor cardiovascular diseas cvd howev whether notion appli east asian popul type diabet td establish studi investig associ remnant c concentr risk cvd korean patient td	D002318;D003924;D006949;D009203;D000083242	T033;T047
36,324,176	apolipoprotein e imbal cerebrospin fluid alzheim diseas patient purpos studi examin level cerebrospin fluid csf apolipoprotein e apo speci alzheim diseas ad patient	D000544	T047;T048
36,324,173	feasibl accept implement video reflex ethnographi vre improv tool acut matern servic video reflex ethnographi vre argu altern approach collabor learn healthcar team abl captur complex healthcar environ simul studi aim explor feasibl accept employ vre improv tool acut matern servic	D000884;D010348	T090;T058
36,324,171	new approach expedit deliveri final crown teeth requir crown lengthen surgeri pilot studi heal period crown lengthen procedur clps often delay final crown deliveri studi aim explor feasibl new approach expedit deliveri final crown teeth requir clps	D016556;D003442	T061;T074
36,324,169	dynam alter gut microbiota metabolom huanjiang mini pig pregnanc matern gut microbiota metabolit associ offspr health previous studi show matern bodi fat percentag increas day gestat huanjiang mini pig model thus studi aim investig chang gut microbiota composit microbi metabolit profil sow day gestat	D000069196;D064307	T032;T007;T028;T001
36,324,168	advantag vitrif preserv assist reproduct potenti influenc imprint gene cryopreserv import applic assist reproduct technolog art vitrif techniqu wide use cryopreserv oocyt embryo larg number clinic result experiment studi shown vitrif achiev higher cell surviv rate preimplant develop rate better pregnanc outcom ovarian tissu vitrif altern method slow freez caus compar less damag origin follicular dna present sperm preserv main adopt slow freez rapid freez ln vapor method although vitrif method achiev higher sperm motil warm howev due use high concentr cryoprotect ultra rapid cool vitrif may caus strong stress gamet embryo tissu cell result potenti advers effect imprint gene regul epigenet modif includ dna methyl show singl allel express accur regul correct express import placenta fetal develop offspr health consid genom imprint sensit chang extern environ comprehens summar effect cryopreserv especi vitrif method art imprint gene anim studi found vitrif oocyt embryo signific impact imprint gene dna methyl studi human report almost influenc need explor review provid use inform safeti assess optim current cryopreserv techniqu art	D058989;D013081	T070;T043
36,324,167	health relat qualiti life among person initi mild moder sever critic covid month infect prospect cohort studi current limit evid long term impact physic social emot function ie health relat qualiti life hrql mild moder covid requir hospit compar hrql among person initi mild moder severecrit covid month follow ill onset dutch popul norm investig impact restrict public health control measur hrql	D011788;D000086382	T078;T047;T067
36,324,160	low densiti lipoprotein cholesterol goal attain patient clinic evid famili hypercholesterolemia elev lp although potent lipid lower therapi avail patient common fall short recommend low densiti lipoprotein cholesterol ldl c level aim studi examin relationship famili hypercholesterolemia fh elev lipoprotein lp ldl c goal attain well preval sever coronari arteri diseas cad moreov character patient fail meet recommend ldl c goal	D006938;D003324	T047
36,324,159	factor associ formal inform resourc util nurs home patient without dementia cross section analys cosmos trial investig associ clinic demograph organiz factor formal health profession inform relat resourc util nurs home patient without dementia	D000203;D003704	T056;T048;T080
36,324,157	plasma amyloid beta oligom relat subject cognit declin brain amyloid status subject cognit declin scd target alzheim diseas predict plasma amyloid beta oligom ao pathogen form blood recent propos novel blood base biomark ad predict repres brain deposit relationship plasma ao brain deposit scd individu normal object cognit investig	D060825;D000544;D000686	T047;T048
36,324,156	longitudin effect sit stand desk intervent persist fade psycholog momentum random control trial studi examin whether effect sit stand desk ssd intervent employe musculoskelet complaint ie intens preval activ ie vigil vital persist fade whether veloc acceler health improv predict medium term six month long term month improv draw dynam model self regul well psycholog momentum theori hypothes veloc acceler health improv earli stage intervent would predict medium term health improv sustain long term	D017132;D016272	T078;T091;T082
36,324,155	person oral health relat qualiti life result onlin survey investig associ person factor oral health relat qualiti life	D011788;D010551	T078;T041
36,324,154	p statanxa axi promot caspas mediat hepatocyt pyroptosi non alcohol steatohepat explor role annexin anxa hepatocyt pyroptosi hepat fibrosi nonalcohol steatohepat nash under molecular mechan	D017306;D065626	T123;T047;T116
36,324,152	pstpip regul synovi macrophag polar dynam via er joint microenviron cytoskelet protein pstpip associ inflamm predomin express macrophag previous data shown pstpip inhibit articular bone damag arthrit rat aim studi explor molecular mechan pstpip resist bone eros	D001172;D047629	T047;T116;T192
36,324,151	sex differ alzheim diseas plasma mmp marker diseas sever studi report higher plasma matrix metalloproteinas mmp level mild cognit impair mci alzheim diseas ad despit evid mmp activ influenc ad pathophysiolog may modul sex hormon sex differ associ mmp ad biomark cognit explor	D000544;D060825	T047;T048
36,324,150	consequ spill gallston laparoscop cholecystectomi systemat review complic secondari spill gallston classifi categori diseas medic progress prior advent laparoscop cholecystectomi report publish topic aim present studi investig predispos factor complic rate spill gallston laparoscop cholecystectomi past year	D017081;D042882	T061;T031
36,324,148	would nt join nt onlin understand older peopl engag teleyoga class fall prevent yoga base exercis promis strategi promot healthi age potenti reduc fall increas physic cognit psycholog wellb teleyoga real time yoga provid via interact videoconferenc deliv yoga program scale potenti reduc cost increas conveni reach peopl attend studio base class better understand older peopl perceiv engag teleyoga need optimis design implement promot	D000058;D015013	T061;T037
36,324,146	associ triglycerid glucos index risk cerebrovascular diseas systemat review meta analysi triglycerid glucos tyg index new surrog indic insulin resist ir thought associ mani diseas cardiovascular diseas relationship cerebrovascular diseas still controversi	D007333;D002561	T047;T046
36,324,145	psoriat arthriti success treat second line anti interleukin treatment case report review literatur psoriat arthriti treatment antitumor necrosi factor shown reduc diseas activ nonetheless patient achiev suffici respons tumor necrosi factor blocker current treatment interleukin inhibitor expect effect suppress joint destruct patient psoriat arthriti howev evid regard efficaci limit report	D015535;D018501	T121;T047
36,324,144	primari health care platform address racial discrimin leav one behind reduc health inequ health inequ face popul experienc racial discrimin includ indigen peopl peopl african descent roma ethnic minor issu global concern health system import role play tackl health inequ health system base comprehens primari health care phc best place tackl health inequ phc encompass whole societi approach health phc includ action address wider social determin health multisector polici action intercultur integr healthcar servic communiti empower focus address health inequ phc also serv platform introduc specif action tackl racial discrimin act drive wider societ chang tackl racial ethnic health inequ	D063505	T054
36,324,143	gender differ chang metabol syndrom status compon risk cardiovascular diseas longitudin cohort studi aim investig gender differ associ chang metabol syndrom met compon risk cardiovascular diseas cvd coronari heart diseas chd among adult particip tehran lipid glucos studi cohort	D024821;D002318;D003327;D006973	T047
36,324,141	distinct implic bodi mass index differ subgroup nonobes patient heart failur preserv eject fraction latent class analysi data topcat trial obes well defin risk factor heart failur preserv eject fraction hfpef associ better prognosi patient diagnos hfpef paradox poor prognosi nonobes patient hfpef may driven subset high risk patient suggest nonobes hfpef subpopul heterogen	D006333	T047;T046
36,324,140	target enrich long read sequenc telseq contextu antimicrobi resist gene metagenom metagenom data use profil high import gene within microbiom howev current metagenom workflow produc data suffer low sensit inabl accur reconstruct partial full genom particular low abund limit preclud coloc analysi ie character genom context gene function within metagenom sampl genom context especi crucial function associ horizont gene transfer hgt via mobil genet element mges exampl antimicrobi resist amr overcom current limit metagenom present method comprehens accur reconstruct antimicrobi resist gene arg mges metagenom dna term target enrich long read sequenc telseq	D054892;D000900	T121;T195;T028
36,324,139	methylen blue intract pain oral mucos relat cancer treatment random phase clinic trial oral mucos om patient receiv cancer therapi thus far well manag standard approach aim assess safeti effect methylen blue mb oral rins om pain patient receiv cancer therapi	D010148;D013280;D009369	T184;T047;T191
36,324,138	long term prophylaxi androgen manag hereditari angioedema hae emerg countri hereditari angioedema hae rare autosom domin genet diseas character repetit subcutan submucos angioedema activ kinin system increas vascular permeabl c inhibitor c inh defici main mechan hae pathogenesi occur abnorm activ plasma kallikrein bradykinin factor xii mutat gene serp caus quantit function c inh defect although androgen approv hae treatment mani countri wide use china brazil reduc frequenc sever hae attack long term advers effect androgen treatment concern physician patient viril weight gain acn hirsut liver damag headach myalgia hematuria menstrual disord diminish libido arteri hypertens dyslipidemia anxietydepress common observ long term treatment androgen advers effect affect qualiti life hae patient often lead treatment interrupt especi women children depth studi pathogenesi hae led approv altern treatment strategi includ plasma deriv c inhibitor recombin human c inhibitor plasma kallikrein inhibitor ecallantid lanadelumab bradykinin b receptor antagonist icatib achiev satisfactori result most non serious side effect therefor new standard medic care may expand possibl manag hae emerg countri	D054179	T047
36,324,136	examin socioeconom status dispar facil base childbirth kenya role perceiv need access qualiti care give birth health facil skill birth attend sbas one key effort promot reduc prevent matern death sub saharan africa howev research reveal larg socioeconom status ses dispar facil base childbirth seek extend literatur factor under ses dispar draw dispar skill birth attend disba framework examin contribut three proxim factor perceiv need access qualiti care influenc use sbas	D006297;D008427	T033;T058;T080
36,324,135	novel deep learn base method covid pneumonia detect ct imag sensit rt pcr diagnos covid chest ct play indispens role auxiliari diagnosi covid pneumonia result ct imag high depend profession radiologist	D000086382;D000077321	T047;T066;T067
36,324,134	incid risk factor postop medial shoulder imbal lenk type adolesc idiopath scoliosi later shoulder balanc clinic practic signific percentag lenk ai patient suffer medial shoulder imbal msi despit achiev good later shoulder balanc lsb follow surgeri howev studi evalu featur medial shoulder object studi determin incid independ risk factor msi lsb lenk ai correct surgeri	D012600;D013123;D007738	T061;T047;T190
36,324,133	clinic applic artifici neural network ann model predict brca germlin deleteri variant chines bilater primari breast cancer patient bilater breast cancer bbc well ovarian cancer signific associ germlin deleteri variant brca brca germlin deleteri variant carrier exquisit benefit poli adp ribos polymeras parp inhibitor howev formal genet test could carri patient due extens use healthcar resourc turn result high medic cost date exist brca deleteri variant predict model develop women european descent quit genet differ asian popul therefor urgent clinic need tool predict frequenc brca deleteri variant asian bbc patient balanc increas demand cost cancer genet servic	D001943;D010051	T191
36,324,132	specialis paediatr palliat care assess famili healthcar profession health system outcom multi site context various care set sphaera studi protocol number children adolesc live life limit condit potenti need specialis paediatr palliat care sppc rise ideal specialis multiprofession team respond complex healthcar need children famili question sppc benefici circumst remain larg unansw current literatur studi overal target evalu effect sppc programm switzerland respect potenti improv patient famili health profession healthcar relat outcom	D064946;D010166	T061;T058;T091
36,324,131	avail comprehens emerg obstetr neonat care develop region ethiopia lesson learn usaid transform health activ collabor partner ethiopian govern implement standard emerg obstetr neonat care servic cemonc sinc howev limit studi document lesson learn program avail cemonc signal function studi investig avail cemonc signal function describ lesson learn transform health support develop region state ethiopia	D002585;D063130	T061;T040;T079
36,324,129	tranexam acid pertrochanter fractur retrospect analysi periop outcom fixat proxim femor nail treatment pertrochanter femor fractur often associ signific blood loss alreadi demonstr administr tranexam acid txa endoprosthet procedur reduc blood loss lead decreas frequenc postop complic aim studi demonstr whether administr txa part osteosynthesi treatment pertrochanter fractur use proxim femor nail reduc periop blood loss haemorrhag relat complic	D014148;D000933;D005264	T121;T037;T109
36,324,128	target tumor stroma cancer therapi tumor compris cancer cell surround stromal compon essenti part tumor microenviron tumor stroma high dynam heterogen common tumor type specif main includ noncellular composit extracellular matrix uniqu cancer associ vascular system well wide varieti cellular compon includ activ cancer associ fibroblast mesenchym stromal cell pericyt element oper coordin fashion collect promot cancer initi progress metastasi therapeut resist past decad numer studi conduct studi interact crosstalk stromal compon neoplast cell meanwhil also wit exponenti increas investig recognit critic role tumor stroma solid tumor seri clinic trial target tumor stroma launch continu review introduc discuss current advanc understand various stromal element role cancer also elabor potenti novel approach tumor stroma base therapeut target aim promot leap bench bedsid	D009369;D000072645;D059630	T191;T025
36,324,127	random control trial evalu effect novel mouth rins patient gingiv singl center random control trial aim determin effect novel biofilm disrupt mouth rins combin cetylpyridinium chlorid cpc essenti oil prevent accumul supragingiv plaqu supragingiv microbiom patient gingiv dental prophylaxi	D003773;D000891;D005891	T121;T047
36,324,126	scleros encapsul periton dog pancreat ductal adenocarcinoma scleros encapsul periton sep rare clinic syndrom characteris fibrosi thicken peritoneum massiv adhes abdomin organ human abdomin tumour pancreat adenocarcinoma under diseas sep report describ case sep dog pancreat ductal adenocarcinoma	D010538;D000230;D010190;D004283	T047;T046;T191
36,324,123	sever intrahepat cholestasi pregnanc due sertoli leydig cell tumour woman polycyst ovari syndrom case report intrahepat cholestasi pregnanc icp common gestat complic character pruritus elev bile acid usual occur third trimest serum estrogen progesteron level highest hyperandrogen pregnanc patholog state most induc polycyst ovari syndrom pcos rare concomit androgen secret ovarian tumour date correl drawn icp hyperandrogen	D011085;D017588;D018310;D010051	T047;T191
36,324,122	nutrit defici induc nucleus pulposus cell apoptosi via atf pkm akt signal axi intervertebr disc largest avascular tissu human bodi nucleus pulposus np consum glucos oxygen generat energi maintain cellular metabol via nutrient diffus cartilag endplat microenviron intervertebr disc becom nutrit defici degener nutrit defici shown inhibit viabil prolifer np cell	D055959;D044342;D000070614	T047;T023;T190
36,324,121	damn damn nt qualit explor parent motiv provis mobil screen devic earli childhood explor parent motiv provid smartphon tablet young children import better understand way optimis healthi use mobil screen earli childhood date studi qualit examin factor underpin parent motiv provid mobil screen young children use theoret driven approach	D010290;D034201	T099;T102;T073
36,324,120	health behaviour well among older adult surinames migrat background netherland studi aim identifi relationship health behaviour healthi diet physic activ smoke social activ well among older adult surinames background	D014675;D005638	T168;T002
36,324,119	effect probiot administr patient prediabet meta analysi systemat review paper aim examin effect probiot eight factor prediabet popul meta analysi name fast blood glucos fbg glycat haemoglobin ac hbac homeostat model assess insulin resist homa ir quantit insulin sensit check index quicki total cholesterol tc triglycerid tg high densiti lipoprotein cholesterol hdl c low densiti lipoprotein cholesterol ldl c mechan action summar exist studi	D011236;D019936	T047;T007
36,324,118	snack reason detangl effect socio econom posit stress snack behaviour snack consid cornerston unhealthi diet investig psycholog driver snack behaviour urgent therefor purpos studi socio econom posit sep stress known affect mani behaviour outcom therefor focal point studi	D062410;D005247	T168;T040;T055;T079
36,324,116	sociodemograph characterist clinic featur late life depress patient result beij and hospit mental health big data platform sociodemograph characterist clinic featur late life depress lld patient psychiatr hospit thorough studi china studi aim explor psychiatr outpati attend lld patient psychiatr hospit china subgroup analysi without anxieti gender differ	D003863;D004365	T184;T121;T123;T048
36,324,114	influenc obes function outcom patient satisfact week total knee arthroplasti result prospect fingk studi investig obes versus non obes subject knee joint function stiff pain expect outcom satisfact two month total knee arthroplasti tka	D019645;D020370	T061;T047
36,324,113	methadon switch refractori cancer pain methadon common consid altern opioid treatment refractori cancer pain studi aim investig efficaci safeti cost methadon treatment refractori cancer pain	D000072716;D059390;D009369	T184;T191
36,324,112	felin case multipl myeloma treat bortezomib multipl myeloma mm uncommon neoplasm cat establish standard treatment due rare occurr diseas cat bortezomib proteasom inhibitor serv first line drug mm human effect current unknown felin mm present case report felin mm exhibit favor respons bortezomib	D009101;D010198;D010265;D002371	T047;T191
36,324,111	associ serum albumin day mortal chines hakka patient non apl acut myeloid leukemia retrospect cohort studi acut myeloid leukemia aml main type adult leukemia day mortal vital clinic problem doctor face begin treatment studi associ serum albumin day mortal aml non apl limit	D012709;D015470	T123;T191;T116
36,324,110	air pollut refrain visit health facil cross section studi domest migrant china local environment factor associ health healthcar seek behavior howev pauciti literatur document link air pollut healthcar seek behavior studi aim address gap literatur cross section studi domest migrant china	D000393;D014171;D000397	T131;T098;T069;T080
36,324,109	observ laser photocoagul anti vegf therapi manag retin arteri macroaneurysm explor efficaci observ laser photocoagul anti vegf manag retin arteri macroaneurysm ram	D000080346	T047;T020
36,324,108	effect revis wic food packag women children health quasi experiment studi special supplement nutrit program women infant children wic revis congruent nation dietari guidelin limit research examin effect revis women children health object studi evalu whether revis wic food packag associ various indic physic mental health women children	D063105;D000086382	T047;T064;T067;T057
36,324,107	predict valu fibrinogen occurr mild cognit impair event patient diabet peripher neuropathi research suggest fibrinogen fib relat mild cognit impair mci diabet peripher neuropathi dpn risk mci patient dpn great increas although studi evalu predict valu fib risk mci patient dpn	D003929;D003924;D060825	T047;T048
36,324,106	compar studi diseas burden attribut asbesto brazil china kazakhstan russia brazil china kazakhstan russia main asbesto produc countri form asbesto carcinogen human object studi estim diseas burden attribut asbesto major produc countri includ brazil china kazakhstan russia	D001194;D009369	T131;T197;T191
36,324,105	primipar women knowledg diastasi recti abdomini concern abdomin appear treatment perceiv abdomin muscl strength month postpartum cross section comparison studi diastasi recti abdomini dra preval condit postpartum period date scant knowledg dra influenc physic mental emot health studi investig primipar women knowledg dra concern abdomin appear perceiv abdomin muscl strength compar women without report dra	D017568;D000070630	T023;T190
36,324,104	accuraci spontan breath trial use combin cpap psv model predict extub outcom preterm infant preterm infant often requir mechan ventil howev object criteria predict outcom extub prematur neonat remain lack aim studi investig accuraci spontan breath trial sbt use combin model continu posit airway pressur cpap low level pressur support ventil psv predict extub outcom preterm infant gestat age week	D060666;D007235	T061;T047
36,324,103	effect oral motor facilit techniqu oral motor feed skill children cerebr palsi case studi defici oral motor function feed skill common children cerebr palsi cp oral motor therapi use method improv oral motor function feed skill oral motor facilit techniqu omft newli design comprehens oral motor therapi includ postur control sensori adapt breath control sensorimotor facilit direct feed	D002547	T019;T047
36,324,101	decision balanc attitud practic behavior predict factor relat experi advanc care plan taiwanes patient advanc cancer patient advanc cancer prone experi burdensom physic psycholog financi consequ healthcar provid may fulli appreci advanc cancer patient medic care autonomi embod advanc care plan acp may compromis qualiti end life eol henc essenti healthcar provid effect assess communic patient regard medic decis patient incapacit diseas progress purpos investig describ decision balanc attitud practic behavior acp predictor acp relat experi taiwanes patient advanc cancer	D032722;D010820;D009369	T058;T191;T097
36,324,100	effect omicron variant perinat outcom full term neonat research coronavirus diseas covid effect newborn ongo research specif variant effect none studi analyz effect omicron variant perinat outcom full term newborn omicron wave period method decemb april studi conduct newborn visit singl center investig due omicron matern infect matern pregnanc complic deliveri method birth week apgar score neonat resuscit program requir whether respiratori support requir h childbirth suspici infecti status mortal depend matern omicron infect	D000086382;D007232;D011248;D011251	T047;T046;T067
36,324,099	obes paradox among patient undergo total knee arthroplasti retrospect cohort studi obes recogn risk factor postop complic surgic patient howev recent studi show protect effect obes surgic non surgic patient studi examin associ bodi mass index bmi earli postop complic patient undergo total knee arthroplasti	D019645;D009767	T061;T047
36,324,098	investig role x chromosom inactiv androgen receptor cag repeat polymorph patient recurr pregnanc loss prospect case control studi previous research reveal skew x chromosom inactiv sxci androgen receptor ar cag polymorph associ increas risk recurr pregnanc loss rpl howev result conflict under mechan remain unclear studi investig role sxci ar cag polymorph patient rpl explor whether under mechan relat ovarian reserv preimplant embryo aneuploidi	D049951;D000026	T045;T047
36,324,097	secundipara follow fail vacuum deliveri factor associ success vagin deliveri histor prospect cohort studi focus deliveri subsequ fail vacuum deliveri fail vd secundipara object current studi examin factor associ vagin deliveri follow fail vd	D036861;D014620	T061
36,324,096	develop applic tfa macrosimul model case studi model impact tran fatti acid tfa elimin polici brazil consumpt tran fatti acid tfa direct associ cardiovascular diseas risk respons signific health burden global polici strategi reduc tfa includ limit content food elimin partial hydrogen oil pho market studi aim describ compar risk assess macrosimul model appli tool estim potenti reduct cvd mortal gain compar scenario tfa reductionelimin brazil	D044242;D003327	T168;T047
36,324,095	outcom prognost factor patient underw reoper persistentrecurr papillari thyroid carcinoma suitabl approach treat persistentrecurr papillari thyroid carcinoma ptc remain controversi reoper may consid effect method efficaci reoper patient locoregion persistentrecurr ptc especi unsatisfactori radioact iodin rai ablat result still uncertain studi aim clarifi clinic manag strategi locoregion persistentrecurr ptc explor factor may affect long term patient outcom reoper	D002291;D013964	T191
36,324,094	nomogram combin clinic factor biomark predict recurr high risk cutan squamous cell carcinoma although determin recurr cutan squamous cell carcinoma cscc import current suggest system singl biomark limit power predict recurr	D002294;D012878	T191
36,324,093	morpholog differ scoliosi curvatur caus difficulti earli detect base angl trunk inclin three dimension deform spine scoliosi specif given child regard number length curvatur degre rotat size curvatur angl earli diagnosi scoliosi clinic examin accord adam test depend correl angl trunk inclin ati cobb angl adopt diagnosi criterion aim studi demonstr need adopt differ diagnost criteria ati depend age locat scoliosi moreov observ differ aticobb correl becam basi propos introduc concept low medium high rotat curvatur clinic descript scoliosi	D012600	T047
36,324,091	cerebr blood flow abnorm central spare arteri spin label mild encephalopathi associ excitotox case report acut encephalopathi biphas seizur late reduc diffus aesd mild encephalopathi associ excitotox meex frequent acut encephalopathi pediatr patient japan aesd typic present biphas seizur delay reduc diffus subcort area call bright tree appear bta radiolog examin patient aesd arteri spin label asl show decreas cerebr blood flow cbf hyperacut stage increas cbf acut stage suggest use asl earli diagnosi aesd addit proton magnet reson spectroscopi mrs show elev glutam glu glutamin gln aesd meex group mild encephalopathi transient elev gln mrs similar aesd howev meex includ clinic biphas cours abnorm includ bta diffus weight imag although use asl aesd report report patient meex studi report experi year old girl diagnos meex show uniqu find asl	D001927;D003294	T047
36,324,089	understand rural urban dispar acut respiratori infect symptom among five children sub saharan africa multivari decomposit analysi acut respiratori infect ari account worldwid diseas burden children age five major occur sub saharan africa rural children vulner disproportion affect ari result examin rural urban dispar preval ari symptom associ factor among children age five sub saharan africa	D012141;D015362	T047
36,324,088	studi protocol transcrani electr stimul alpha frequenc appli rehabilit random control trial chronic stroke patient visuospati neglect frequent post stroke disord later attent visuospati neglect vsn vsn strong negat impact recoveri general independ daili life optim treatment deem urgent next tradit stroke treatment non invas brain stimul offer potenti facilit stroke recoveri complementari approach present studi visual scan train vst current convent treatment combin transcrani altern current stimul tac evalu addit effect repeat session tac combin six week vst rehabilit	D065908;D000071939;D010468;D020521	T061;T047;T048
36,324,087	nomogram predict cancer specif surviv elder patient gallbladd cancer gallbladd cancer gbc high aggress malign elder patient goal aim construct novel nomogram predict cancer specif surviv css elder gbc patient	D049451;D005706	T081;T170;T191
36,324,086	dementia risk predict individu mild cognit impair comparison cox regress machin learn model cox proport hazard regress model machin learn model wide use predict risk dementia exist comparison model most base empir dataset yield mix result studi examin accuraci various machin learn cox regress model predict time event outcom use mont carlo simul peopl mild cognit impair mci	D060825;D003704	T048
36,324,085	gmmchi gene express cluster use gaussian mixtur model cancer evolut consist stepwis acquisit genet epigenet chang alter gene express profil cell particular tissu result phenotyp alter act upon natur select recurr appear specif genet lesion across individu cancer cancer type suggest exist certain driver mutat like make major contribut tumor select advantag surround normal tissu respons consequenti aspect cancer cell gene express pattern phenotyp hypothes mutat like cluster specif dichotom shift express gene close control propos gmmchi python packag leverag gaussian mixtur model detect character bimod gene express pattern across cancer sampl tool analyz correl use conting tabl statist	D020869;D000465	T063;T170;T059
36,324,084	impact covid irish emerg depart ed cross section studi explor factor influenc ed utilis prior pandem patient perspect collater damag sar cov serious concern emerg medicin em communiti specif relat delay care increas morbid mortal attend unrel covid object studi describ profil patient attend irish ed prior pandem investig factor influenc ed utilis cohort	D058873;D000086382	T047;T067
36,324,083	evolut cbl cipk gene famili medicago genom wide character pervas duplic express pattern salt drought stress calcineurin b like protein cbls ubiquit ca sensor mediat plant respons various stress development process interact cbl interact protein kinas cipk cbls cipk play essenti role acclimat crop plant howev evolut two gene famili genus medicago poor understood	D055864;D010940	T070;T116
36,324,081	effect vari inhal oxygen concentr high flow nasal cannula oxygen therapi gastroscopi propofol sedat elder patient random control studi despit evid high flow nasal cannula oxygen therapi hfnc promot oxygen applic sedat gastroscopi elder patient receiv littl attent studi investig effect differ inhal oxygen concentr fio hfnc sedat gastroscopi elder patient	D015742;D000402;D012131	T121;T047;T046;T109
36,324,080	relationship genet risk score cardiometabol risk factor cross section studi eight decad cardiovascular diseas cvd remain lead caus death world cvd risk factor multifacet genet lifestyl play role aim studi investig associ genet profil risk score obes grs cardio metabol risk factor overweight obes women	D050177;D002318	T033;T047
36,324,078	chronic inflammatori demyelin polyneuropathi psoriasi comorbid signific allevi symptom secukinumab case report chronic inflammatori demyelin polyneuropathi cidp autoimmun diseas involv damag peripher nervous system cours diseas progress week frequent incid relaps remiss cours articl report rare combin cidp fluctuat symptom recurr remiss comorbid psoriasi	D020277;D011565	T047
36,324,077	immunomodulatori effect defensin macrophag induc immuno upregul antitumor function breast cancer macrophag mononuclear cd antigen present cell defens mechan play dual role tumor burden immunomodulatori antitumor function defensin still unclear despit accumul evid respons infect aim present studi elucid role defensin level ros cytokin chemokin express macrophag antitumor function breast cancer	D023083;D009369	T191;T116
36,324,076	recurr headach visual symptom young man rare neuron intranuclear inclus diseas case report neuron intranuclear inclus diseas niid progress neurodegen diseas patient niid may present heterogen clinic symptom includ episod encephalopathi dementia limb weak cerebellar ataxia autonom dysfunct among niid case report china patient often complic sever manifest therefor mani clinician consid diseas patient present relat minor complaint	D019636;D008881;D004827	T033;T047
36,324,075	retrospect analysi sar cov omicron invas delta french region status base multi variant model sar cov rapid spread diseas affect human life economi global scale diseas caus far million death omicron outbreak emerg botswana south africa spread around globe increas rate caus unpreced sar cov infect incid sever countri start decemb first omicron case report franc	D000086402;D000086382	T005;T067;T047
36,324,074	mitochondri genom analys provid new insight miss atp adapt evolut mytilida mytilida also known marin mussel wide distribut ocean worldwid member mytilida show tremend rang ecolog adapt speci distribut freshwat inhabit deep sea mitochondria play import role energi metabol might contribut adapt mytilida differ environ addit bivalv speci thought lack mitochondri protein code gene atp synthas f subunit increas studi indic absenc atp may caus annot difficulti atp gene character high diverg variabl length	D054629;D049879	T204;T028
36,324,073	multilay dynam perturb analysi method predict ligand protein interact ligand protein interact play key role defin protein function detect natur ligand given protein thus import bioengin task particular rapid develop ai base structur predict algorithm batch structur model high reliabl accuraci obtain low cost give rise urgent requir predict natur ligand base protein structur recent year although sever structur base method develop predict ligand bind pocket ligand bind site accur rapid method still lack especi predict ligand bind region spatial extens ligand pocket	D011506;D000465	T123;T170;T116
36,324,072	incid predictor acut kidney injuri among women sever pre eclampsia mbarara region referr hospit presenc acut kidney injuri aki pre eclampsia complic treatment includ increas length hospit stay need access servic like dialysi larg expens resourc limit set aim determin incid predictor acut kidney injuri among women sever pre eclampsia mbarara region referr hospit southwestern uganda	D011225;D004461;D058186	T047;T046;T037
36,324,070	aberr cytokeratin express hepatocyt predict ductopenia grade primari biliari cholang aberr cytokeratin express hepatocyt ck hs hallmark characterist cholestasi diseas especi ductopenia diseas primari biliari cholang pbc studi attempt evalu differ relationship clinic histolog featur aberr cytokeratin ck express hepatocyt pbc patient	D008105;D002779;D002761	T047
36,324,069	role bilirubin prognosi coronari arteri diseas relationship cardiovascular risk factor meta analysi bilirubin heme catabol product antioxid anti inflammatori anti apoptot properti implic prognosi sever diseas studi evalu prognost role bilirubin coronari arteri diseas cad patient	D003324;D009203	T047
36,324,067	histogram base analysi diffus weight imag predict aggress papillari thyroid carcinoma assess potenti appar diffus coeffici adc map predict aggress papillari thyroid carcinoma ptc base whole tumor histogram base analysi	D038524;D013964	T060;T191
36,324,066	zero augment beta prime model multilevel semi continu data bayesian infer semi continu data character excess proport zero right skew continu posit valu appear frequent medic research one exampl would pharmaceut expenditur pe data substanti proport subject investig may report zero two part mix effect model develop analys cluster measur semi continu data multilevel studi studi propos new flexibl two part mix effect model skew distribut nest semi continu cost data framework bayesian approach propos model specif consist two mix effect model link correl random effect part model occurr posit valu use general logist mix model part ii model magnitud posit valu use linear mix model model error follow skew distribut includ beta prime bp propos method illustr pharmaceut expenditur data multilevel observ studi analyt result report compar potenti model differ skew distribut simul studi conduct assess perform propos model dic lpml waic loo bayesian model select criteria measur diverg use compar model	D015233	T081;T170
36,324,064	teapv comprehens genom variat databas tea plant camellia sinensi genom variat play import role plant phenotyp model adapt evolut also enhanc popul genet divers regul gene express tea tree camellia sinensi larg genom gb make identif genom wide variant time consum expens continu public larg number differ type popul sequenc data lack open platform integr data identifi variant tea plant genometo integr genet variat confid tea plant popul genom whole genom resequenc transcriptom sequenc hybrid f individu total tb collect mutat site identif base variat inform construct first tea tree variat web servic databas teapv http http liushangtop support user search snp indel sv mutat ssrpolymorph ssr sequenc locat gene id furthermor websit also provid function gene express search differ transcriptom sequenc blast sequenc extract cds mutat loci etcth featur teapv databas make comprehens tea plant genet variat bioinformat platform research also help reveal new function mutat tea plant genom molecular marker assist breed	D028241	T002
36,324,063	speci genet divers relationship benthic macroinvertebr communiti along salin gradient speci genet divers chang parallel result speci genet divers correl sgdc rais question driver influenc biolog level divers sgdc either posit negat depend whether speci divers genet divers measur speci respond opposit way driver use tradit speci divers approach togeth ultra conserv element high throughput sequenc evalu sgdcs benthic macrofauna communiti baltic sea geolog young brackish water sea characteris steep salin gradient low speci rich assess sgdcs six focal marin invertebr speci differ taxonom group differ life histori ecolog function spatial tempor scale give comprehens insight communiti dynam young ecosystem extrins factor might drive sgdcs	D017753;D054712	T070;T034;T082

36,324,277

ventil avoid among critic ill covid patient acut respiratori distress syndrom determin incid signific ventil avoid patient critic coronavirus diseas covid

D000086382;D012128

T047;T067

36,324,259

impact coronavirus diseas pandem ultrasound screen development dysplasia hip follow imag report southeastern turkey investig effect coronavirus diseas restrict ultrasound us screen development dysplasia hip ddh children hospit

D006618;D000086382;D000082602

T019;T047;T067

36,324,258

n methyladenosin reader ythdf regul melanoma metastasi via executorloxl number studi demonstr n methyladenosin play vital role patholog process various tumour recent found writer eras affect tumourigenesi melanoma howev relationship reader yth domain famili ythdf protein melanoma still elus

D016601;D008545

T123;T191;T116

36,324,254

success extracorpor membran oxygen patient central airway obstruct due endotrach mass extracorpor membran oxygen ecmo assist blood circul gas exchang via heart lung machin ecmo use main intens care unit bridg therapi heart respiratori failur address transplant perform ecmo sometim use surgeri general anaesthesia depend patient under diseas natur oper oxygen suppli carbon dioxid remov capac limit venoven vv ecmo help describ use vv ecmo surgic resect endotrach mass rigid bronchoscopi patient develop decompens dyspnoea due central airway obstruct cao

D015199;D000402;D012131

T061;T047;T046

36,324,250

ultrastructur morpholog characterist anterior cruciat ligament pig studi use tesla diffus tensor imag diffus tensor imag research anterior cruciat ligament acl limit studi reveal acl fibrous microstructur tesla magnet reson imag therefor use magnet reson imag assess acl

D016118;D056324

T060;T023

36,324,246

associ nadir hematocrit sever acut kidney injuri pump coronari arteri bypass graft surgeri retrospect cohort studi base mimic iv databas background aim evalu associ postop nadir hematocrit hct sever acut kidney injuri aki patient undergo pump coronari arteri bypass graft opcabg surgeri materi method data patient receiv opcabg extract medic inform mart intens care iv mimic iv databas general addit model appli explor relationship nadir hct sever aki patient divid group quartil postop nadir hct lowest group hct refer conduct multivari logist regress model calcul adjust odd ratio ci evalu trend among group result total opcabg patient includ nonlinear associ nadir hct sever aki identifi adjust potenti confound nadir hct negat associ risk sever aki hct less statist signific highest hct group hct control group hct test trend signific p subgroup analys show increas postop nadir hct associ decreas risk sever aki p lower bmi group kgm conclus associ postop nadir hct sever aki patient opcabg nonlinear lower nadir hct may associ increas risk sever aki hct valu less howev statist signific found highest hct group control group

D047549;D058186

T061;T047;T037

36,324,242

recurr gastrointestin bleed due small bowel vascular malform patient turner syndrom diagnos surgic assist push enteroscopi background obscur gastrointestin bleed account approxim case gastrointestin bleed frequent site small bowel turner syndrom ts genet disord second x chromosom femal associ gastrointestin vascular malform turner syndrom describ case report vascular malform turner syndrom vari asymptomat sever recurr gi bleed data diagnosi manag patient lack case report year old girl ts present recurr symptomat melena initi work includ negat upper endoscopi negat bidirect endoscopi video capsul endoscopi vce demonstr larg amount blood small erythemat lesion small bowel without activ bleed negat meckel scan ct angiographi remark promin left lower mesenter blood vessel singl balloon enteroscopi demonstr promin vasculatur throughout small bowel clip place site question bleed patient underw surgic assist push enteroscopi due recurr bleed find consist diffus vascular malform start tranexam acid later transit estrogen therapi without report gi bleed anemia advers effect treatment month initi present conclus small bowel bleed life threat evid base guidelin children need turner syndrom associ gastrointestin vascular malform suspicion diagnosi high patient present gastrointestin bleed estrogen might effect therapi ts adolesc patient set diffus vascular malform dvm

D014424;D053704;D054079;D014652

T060;T047;T190

36,324,241

lung hamartoma resembl lung cancer report three case pulmonari hamartoma benign lung tumor howev difficult distinguish lesion diseas via imag three patient patholog confirm pulmonari hamartoma depart analyz believ necessari combin imag patholog clinic test individu patient assess enabl earlier definit diagnosi pulmonari hamartoma therefor necessari analyz summar clinic manifest imag featur patient pulmonari hamartoma improv earli recognit diseas clinician

D006222;D008175

T191

36,324,239

healthi context paradox reduc bulli come cost certain victim bulli remain one serious problem affect school system around world negat consequ bulli short long term wide document show victim student greater risk suffer psychosoci distress paper first summar current situat bulli prevent adopt contextu perspect briefli highlight characterist effect prevent program second address disturb phenomenon detect classroom bulli reduc intervent term healthi context paradox healthier context student remain situat victim found present poorer psycholog adjust intervent understand caus phenomenon may offer clue prevent bulli regard present three hypothes recent propos explain phenomenon final offer implic studi prevent bulli deriv healthi context paradox

D058445;D019548

T068;T098;T048

36,324,188

longitudin correl fruit veget consumpt depress symptom among middl age older adult south africa fruit veget intak may influenc mental well aim studi assess longitudin associ fruit veget intak depress symptom among rural south african

D014675;D005638

T168;T002

36,324,187

phosphodiesteras pdea novel target suppress catenin ras signal epitheli ovarian cancer lead theori ovarian carcinogenesi propos inflamm associ incess ovul driver oncogenesi consist theori nonsteroid anti inflammatori drug nsaid exert promis chemoprevent activ ovarian cancer unfortun toxic associ long term use nsaid due cyclooxygenas cox inhibitori activ previous studi suggest antineoplast activ nsaid cox independ rather may exert phosphodiesteras pde inhibit pdes repres uniqu chemoprevent target ovarian cancer given ovul regul cyclic nucleotid signal evalu pdea novel therapeut target ovarian cancer analysi cancer genom atlas tcga ovarian tumor reveal pdea overexpress associ signific wors overal surviv patient pdea express also posit correl upregul oncogen inflammatori signal pathway use small molecul inhibitor pf novel nsaid deriv pdea inhibitor mci show pdea inhibit lead decreas ovarian cancer cell growth induc cell cycl arrest apoptosi demonstr pro apoptot properti occur pka pkg signal use specif inhibitor block activ pdea genet knockout ovarian cancer cell crispca edit lead decreas cell prolifer coloni format migrat invas vivo tumor growth also demonstr pdea inhibit lead decreas wnt induc catenin nuclear transloc well decreas egf mediat activ rasmapk akt pathway ovarian cancer cell find implic pdea novel target ovarian cancer chemoprevent treatment

D051176;D010051

T123;T191;T116

36,324,186

trend evolut triatomini tribe hemiptera triatomina reproduct incompat four speci geniculatus clade geniculatus clade compos rufotuberculatus lignarius geniculatus megistus group relat evolutionarili speci genus panstrongylus nesotriatoma sever studi shown triatomin hybrid play import role transmiss chaga diseas natur hybrid speci geniculatus clade never report knowledg thus carri experiment cross speci geniculatus clade help elucid taxonom issu well contribut epidemiolog knowledg group

D014225;D010203;D014355

T047;T204

36,324,182

import caf cancer resist target therapi last two decad clinic oncolog revolution advent target drug howev efficaci therapi signific limit primari acquir resist reli cell autonom mechan also tumor microenviron cue cancer associ fibroblast caf extrem plastic cell tumor microenviron produc extracellular matrix compon build structur tumor stroma also releas growth factor chemokin exosom metabolit affect tumor properti includ respons drug treatment contribut caf tumor progress deepli investig review sever work howev role resist anticanc therapi particular molecular therapi larg overlook review specif dissect role caf drive resist target therapi discuss novel caf target therapeut strategi improv patient surviv

D000072645;D009369;D055354

T026;T191;T025

36,324,178

util health belief model comprehend diarrheal diseas dynam case cryptosporidiosi uganda diarrheal diseas contribut great report global childhood mortal morbid relat social econom consequ studi conduct analyz util health belief model hbm theori comprehend diarrheal diseas dynam uganda

D003457

T047

36,324,177

remnant cholesterol risk cardiovascular diseas type diabet nationwid longitudin cohort studi elev remnant cholesterol remnant c consid risk factor cardiovascular diseas cvd howev whether notion appli east asian popul type diabet td establish studi investig associ remnant c concentr risk cvd korean patient td

D002318;D003924;D006949;D009203;D000083242

T033;T047

36,324,176

apolipoprotein e imbal cerebrospin fluid alzheim diseas patient purpos studi examin level cerebrospin fluid csf apolipoprotein e apo speci alzheim diseas ad patient

D000544

T047;T048

36,324,173

feasibl accept implement video reflex ethnographi vre improv tool acut matern servic video reflex ethnographi vre argu altern approach collabor learn healthcar team abl captur complex healthcar environ simul studi aim explor feasibl accept employ vre improv tool acut matern servic

D000884;D010348

T090;T058

36,324,171

new approach expedit deliveri final crown teeth requir crown lengthen surgeri pilot studi heal period crown lengthen procedur clps often delay final crown deliveri studi aim explor feasibl new approach expedit deliveri final crown teeth requir clps

D016556;D003442

T061;T074

36,324,169

dynam alter gut microbiota metabolom huanjiang mini pig pregnanc matern gut microbiota metabolit associ offspr health previous studi show matern bodi fat percentag increas day gestat huanjiang mini pig model thus studi aim investig chang gut microbiota composit microbi metabolit profil sow day gestat

D000069196;D064307

T032;T007;T028;T001

36,324,168

advantag vitrif preserv assist reproduct potenti influenc imprint gene cryopreserv import applic assist reproduct technolog art vitrif techniqu wide use cryopreserv oocyt embryo larg number clinic result experiment studi shown vitrif achiev higher cell surviv rate preimplant develop rate better pregnanc outcom ovarian tissu vitrif altern method slow freez caus compar less damag origin follicular dna present sperm preserv main adopt slow freez rapid freez ln vapor method although vitrif method achiev higher sperm motil warm howev due use high concentr cryoprotect ultra rapid cool vitrif may caus strong stress gamet embryo tissu cell result potenti advers effect imprint gene regul epigenet modif includ dna methyl show singl allel express accur regul correct express import placenta fetal develop offspr health consid genom imprint sensit chang extern environ comprehens summar effect cryopreserv especi vitrif method art imprint gene anim studi found vitrif oocyt embryo signific impact imprint gene dna methyl studi human report almost influenc need explor review provid use inform safeti assess optim current cryopreserv techniqu art

D058989;D013081

T070;T043

36,324,167

health relat qualiti life among person initi mild moder sever critic covid month infect prospect cohort studi current limit evid long term impact physic social emot function ie health relat qualiti life hrql mild moder covid requir hospit compar hrql among person initi mild moder severecrit covid month follow ill onset dutch popul norm investig impact restrict public health control measur hrql

D011788;D000086382

T078;T047;T067

36,324,160

low densiti lipoprotein cholesterol goal attain patient clinic evid famili hypercholesterolemia elev lp although potent lipid lower therapi avail patient common fall short recommend low densiti lipoprotein cholesterol ldl c level aim studi examin relationship famili hypercholesterolemia fh elev lipoprotein lp ldl c goal attain well preval sever coronari arteri diseas cad moreov character patient fail meet recommend ldl c goal

D006938;D003324

T047

36,324,159

factor associ formal inform resourc util nurs home patient without dementia cross section analys cosmos trial investig associ clinic demograph organiz factor formal health profession inform relat resourc util nurs home patient without dementia

D000203;D003704

T056;T048;T080

36,324,157

plasma amyloid beta oligom relat subject cognit declin brain amyloid status subject cognit declin scd target alzheim diseas predict plasma amyloid beta oligom ao pathogen form blood recent propos novel blood base biomark ad predict repres brain deposit relationship plasma ao brain deposit scd individu normal object cognit investig

D060825;D000544;D000686

T047;T048

36,324,156

longitudin effect sit stand desk intervent persist fade psycholog momentum random control trial studi examin whether effect sit stand desk ssd intervent employe musculoskelet complaint ie intens preval activ ie vigil vital persist fade whether veloc acceler health improv predict medium term six month long term month improv draw dynam model self regul well psycholog momentum theori hypothes veloc acceler health improv earli stage intervent would predict medium term health improv sustain long term

D017132;D016272

T078;T091;T082

36,324,155

person oral health relat qualiti life result onlin survey investig associ person factor oral health relat qualiti life

D011788;D010551

T078;T041

36,324,154

p statanxa axi promot caspas mediat hepatocyt pyroptosi non alcohol steatohepat explor role annexin anxa hepatocyt pyroptosi hepat fibrosi nonalcohol steatohepat nash under molecular mechan

D017306;D065626

T123;T047;T116

36,324,152

pstpip regul synovi macrophag polar dynam via er joint microenviron cytoskelet protein pstpip associ inflamm predomin express macrophag previous data shown pstpip inhibit articular bone damag arthrit rat aim studi explor molecular mechan pstpip resist bone eros

D001172;D047629

T047;T116;T192

36,324,151

sex differ alzheim diseas plasma mmp marker diseas sever studi report higher plasma matrix metalloproteinas mmp level mild cognit impair mci alzheim diseas ad despit evid mmp activ influenc ad pathophysiolog may modul sex hormon sex differ associ mmp ad biomark cognit explor

D000544;D060825

T047;T048

36,324,150

consequ spill gallston laparoscop cholecystectomi systemat review complic secondari spill gallston classifi categori diseas medic progress prior advent laparoscop cholecystectomi report publish topic aim present studi investig predispos factor complic rate spill gallston laparoscop cholecystectomi past year

D017081;D042882

T061;T031

36,324,148

would nt join nt onlin understand older peopl engag teleyoga class fall prevent yoga base exercis promis strategi promot healthi age potenti reduc fall increas physic cognit psycholog wellb teleyoga real time yoga provid via interact videoconferenc deliv yoga program scale potenti reduc cost increas conveni reach peopl attend studio base class better understand older peopl perceiv engag teleyoga need optimis design implement promot

D000058;D015013

T061;T037

36,324,146

associ triglycerid glucos index risk cerebrovascular diseas systemat review meta analysi triglycerid glucos tyg index new surrog indic insulin resist ir thought associ mani diseas cardiovascular diseas relationship cerebrovascular diseas still controversi

D007333;D002561

T047;T046

36,324,145

psoriat arthriti success treat second line anti interleukin treatment case report review literatur psoriat arthriti treatment antitumor necrosi factor shown reduc diseas activ nonetheless patient achiev suffici respons tumor necrosi factor blocker current treatment interleukin inhibitor expect effect suppress joint destruct patient psoriat arthriti howev evid regard efficaci limit report

D015535;D018501

T121;T047

36,324,144

primari health care platform address racial discrimin leav one behind reduc health inequ health inequ face popul experienc racial discrimin includ indigen peopl peopl african descent roma ethnic minor issu global concern health system import role play tackl health inequ health system base comprehens primari health care phc best place tackl health inequ phc encompass whole societi approach health phc includ action address wider social determin health multisector polici action intercultur integr healthcar servic communiti empower focus address health inequ phc also serv platform introduc specif action tackl racial discrimin act drive wider societ chang tackl racial ethnic health inequ

D063505

T054

36,324,143

gender differ chang metabol syndrom status compon risk cardiovascular diseas longitudin cohort studi aim investig gender differ associ chang metabol syndrom met compon risk cardiovascular diseas cvd coronari heart diseas chd among adult particip tehran lipid glucos studi cohort

D024821;D002318;D003327;D006973

T047

36,324,141

distinct implic bodi mass index differ subgroup nonobes patient heart failur preserv eject fraction latent class analysi data topcat trial obes well defin risk factor heart failur preserv eject fraction hfpef associ better prognosi patient diagnos hfpef paradox poor prognosi nonobes patient hfpef may driven subset high risk patient suggest nonobes hfpef subpopul heterogen

D006333

T047;T046

36,324,140

target enrich long read sequenc telseq contextu antimicrobi resist gene metagenom metagenom data use profil high import gene within microbiom howev current metagenom workflow produc data suffer low sensit inabl accur reconstruct partial full genom particular low abund limit preclud coloc analysi ie character genom context gene function within metagenom sampl genom context especi crucial function associ horizont gene transfer hgt via mobil genet element mges exampl antimicrobi resist amr overcom current limit metagenom present method comprehens accur reconstruct antimicrobi resist gene arg mges metagenom dna term target enrich long read sequenc telseq

D054892;D000900

T121;T195;T028

36,324,139

methylen blue intract pain oral mucos relat cancer treatment random phase clinic trial oral mucos om patient receiv cancer therapi thus far well manag standard approach aim assess safeti effect methylen blue mb oral rins om pain patient receiv cancer therapi

D010148;D013280;D009369

T184;T047;T191

36,324,138

long term prophylaxi androgen manag hereditari angioedema hae emerg countri hereditari angioedema hae rare autosom domin genet diseas character repetit subcutan submucos angioedema activ kinin system increas vascular permeabl c inhibitor c inh defici main mechan hae pathogenesi occur abnorm activ plasma kallikrein bradykinin factor xii mutat gene serp caus quantit function c inh defect although androgen approv hae treatment mani countri wide use china brazil reduc frequenc sever hae attack long term advers effect androgen treatment concern physician patient viril weight gain acn hirsut liver damag headach myalgia hematuria menstrual disord diminish libido arteri hypertens dyslipidemia anxietydepress common observ long term treatment androgen advers effect affect qualiti life hae patient often lead treatment interrupt especi women children depth studi pathogenesi hae led approv altern treatment strategi includ plasma deriv c inhibitor recombin human c inhibitor plasma kallikrein inhibitor ecallantid lanadelumab bradykinin b receptor antagonist icatib achiev satisfactori result most non serious side effect therefor new standard medic care may expand possibl manag hae emerg countri

D054179

T047

36,324,136

examin socioeconom status dispar facil base childbirth kenya role perceiv need access qualiti care give birth health facil skill birth attend sbas one key effort promot reduc prevent matern death sub saharan africa howev research reveal larg socioeconom status ses dispar facil base childbirth seek extend literatur factor under ses dispar draw dispar skill birth attend disba framework examin contribut three proxim factor perceiv need access qualiti care influenc use sbas

D006297;D008427

T033;T058;T080

36,324,135

novel deep learn base method covid pneumonia detect ct imag sensit rt pcr diagnos covid chest ct play indispens role auxiliari diagnosi covid pneumonia result ct imag high depend profession radiologist

D000086382;D000077321

T047;T066;T067

36,324,134

incid risk factor postop medial shoulder imbal lenk type adolesc idiopath scoliosi later shoulder balanc clinic practic signific percentag lenk ai patient suffer medial shoulder imbal msi despit achiev good later shoulder balanc lsb follow surgeri howev studi evalu featur medial shoulder object studi determin incid independ risk factor msi lsb lenk ai correct surgeri

D012600;D013123;D007738

T061;T047;T190

36,324,133

clinic applic artifici neural network ann model predict brca germlin deleteri variant chines bilater primari breast cancer patient bilater breast cancer bbc well ovarian cancer signific associ germlin deleteri variant brca brca germlin deleteri variant carrier exquisit benefit poli adp ribos polymeras parp inhibitor howev formal genet test could carri patient due extens use healthcar resourc turn result high medic cost date exist brca deleteri variant predict model develop women european descent quit genet differ asian popul therefor urgent clinic need tool predict frequenc brca deleteri variant asian bbc patient balanc increas demand cost cancer genet servic

D001943;D010051

T191

36,324,132

specialis paediatr palliat care assess famili healthcar profession health system outcom multi site context various care set sphaera studi protocol number children adolesc live life limit condit potenti need specialis paediatr palliat care sppc rise ideal specialis multiprofession team respond complex healthcar need children famili question sppc benefici circumst remain larg unansw current literatur studi overal target evalu effect sppc programm switzerland respect potenti improv patient famili health profession healthcar relat outcom

D064946;D010166

T061;T058;T091

36,324,131

avail comprehens emerg obstetr neonat care develop region ethiopia lesson learn usaid transform health activ collabor partner ethiopian govern implement standard emerg obstetr neonat care servic cemonc sinc howev limit studi document lesson learn program avail cemonc signal function studi investig avail cemonc signal function describ lesson learn transform health support develop region state ethiopia

D002585;D063130

T061;T040;T079

36,324,129

tranexam acid pertrochanter fractur retrospect analysi periop outcom fixat proxim femor nail treatment pertrochanter femor fractur often associ signific blood loss alreadi demonstr administr tranexam acid txa endoprosthet procedur reduc blood loss lead decreas frequenc postop complic aim studi demonstr whether administr txa part osteosynthesi treatment pertrochanter fractur use proxim femor nail reduc periop blood loss haemorrhag relat complic

D014148;D000933;D005264

T121;T037;T109

36,324,128

target tumor stroma cancer therapi tumor compris cancer cell surround stromal compon essenti part tumor microenviron tumor stroma high dynam heterogen common tumor type specif main includ noncellular composit extracellular matrix uniqu cancer associ vascular system well wide varieti cellular compon includ activ cancer associ fibroblast mesenchym stromal cell pericyt element oper coordin fashion collect promot cancer initi progress metastasi therapeut resist past decad numer studi conduct studi interact crosstalk stromal compon neoplast cell meanwhil also wit exponenti increas investig recognit critic role tumor stroma solid tumor seri clinic trial target tumor stroma launch continu review introduc discuss current advanc understand various stromal element role cancer also elabor potenti novel approach tumor stroma base therapeut target aim promot leap bench bedsid

D009369;D000072645;D059630

T191;T025

36,324,127

random control trial evalu effect novel mouth rins patient gingiv singl center random control trial aim determin effect novel biofilm disrupt mouth rins combin cetylpyridinium chlorid cpc essenti oil prevent accumul supragingiv plaqu supragingiv microbiom patient gingiv dental prophylaxi

D003773;D000891;D005891

T121;T047

36,324,126

scleros encapsul periton dog pancreat ductal adenocarcinoma scleros encapsul periton sep rare clinic syndrom characteris fibrosi thicken peritoneum massiv adhes abdomin organ human abdomin tumour pancreat adenocarcinoma under diseas sep report describ case sep dog pancreat ductal adenocarcinoma

D010538;D000230;D010190;D004283

T047;T046;T191

36,324,123

sever intrahepat cholestasi pregnanc due sertoli leydig cell tumour woman polycyst ovari syndrom case report intrahepat cholestasi pregnanc icp common gestat complic character pruritus elev bile acid usual occur third trimest serum estrogen progesteron level highest hyperandrogen pregnanc patholog state most induc polycyst ovari syndrom pcos rare concomit androgen secret ovarian tumour date correl drawn icp hyperandrogen

D011085;D017588;D018310;D010051

T047;T191

36,324,122

nutrit defici induc nucleus pulposus cell apoptosi via atf pkm akt signal axi intervertebr disc largest avascular tissu human bodi nucleus pulposus np consum glucos oxygen generat energi maintain cellular metabol via nutrient diffus cartilag endplat microenviron intervertebr disc becom nutrit defici degener nutrit defici shown inhibit viabil prolifer np cell

D055959;D044342;D000070614

T047;T023;T190

36,324,121

damn damn nt qualit explor parent motiv provis mobil screen devic earli childhood explor parent motiv provid smartphon tablet young children import better understand way optimis healthi use mobil screen earli childhood date studi qualit examin factor underpin parent motiv provid mobil screen young children use theoret driven approach

D010290;D034201

T099;T102;T073

36,324,120

health behaviour well among older adult surinames migrat background netherland studi aim identifi relationship health behaviour healthi diet physic activ smoke social activ well among older adult surinames background

D014675;D005638

T168;T002

36,324,119

effect probiot administr patient prediabet meta analysi systemat review paper aim examin effect probiot eight factor prediabet popul meta analysi name fast blood glucos fbg glycat haemoglobin ac hbac homeostat model assess insulin resist homa ir quantit insulin sensit check index quicki total cholesterol tc triglycerid tg high densiti lipoprotein cholesterol hdl c low densiti lipoprotein cholesterol ldl c mechan action summar exist studi

D011236;D019936

T047;T007

36,324,118

snack reason detangl effect socio econom posit stress snack behaviour snack consid cornerston unhealthi diet investig psycholog driver snack behaviour urgent therefor purpos studi socio econom posit sep stress known affect mani behaviour outcom therefor focal point studi

D062410;D005247

T168;T040;T055;T079

36,324,116

sociodemograph characterist clinic featur late life depress patient result beij and hospit mental health big data platform sociodemograph characterist clinic featur late life depress lld patient psychiatr hospit thorough studi china studi aim explor psychiatr outpati attend lld patient psychiatr hospit china subgroup analysi without anxieti gender differ

D003863;D004365

T184;T121;T123;T048

36,324,114

influenc obes function outcom patient satisfact week total knee arthroplasti result prospect fingk studi investig obes versus non obes subject knee joint function stiff pain expect outcom satisfact two month total knee arthroplasti tka

D019645;D020370

T061;T047

36,324,113

methadon switch refractori cancer pain methadon common consid altern opioid treatment refractori cancer pain studi aim investig efficaci safeti cost methadon treatment refractori cancer pain

D000072716;D059390;D009369

T184;T191

36,324,112

felin case multipl myeloma treat bortezomib multipl myeloma mm uncommon neoplasm cat establish standard treatment due rare occurr diseas cat bortezomib proteasom inhibitor serv first line drug mm human effect current unknown felin mm present case report felin mm exhibit favor respons bortezomib

D009101;D010198;D010265;D002371

T047;T191

36,324,111

associ serum albumin day mortal chines hakka patient non apl acut myeloid leukemia retrospect cohort studi acut myeloid leukemia aml main type adult leukemia day mortal vital clinic problem doctor face begin treatment studi associ serum albumin day mortal aml non apl limit

D012709;D015470

T123;T191;T116

36,324,110

air pollut refrain visit health facil cross section studi domest migrant china local environment factor associ health healthcar seek behavior howev pauciti literatur document link air pollut healthcar seek behavior studi aim address gap literatur cross section studi domest migrant china

D000393;D014171;D000397

T131;T098;T069;T080

36,324,109

observ laser photocoagul anti vegf therapi manag retin arteri macroaneurysm explor efficaci observ laser photocoagul anti vegf manag retin arteri macroaneurysm ram

D000080346

T047;T020

36,324,108

effect revis wic food packag women children health quasi experiment studi special supplement nutrit program women infant children wic revis congruent nation dietari guidelin limit research examin effect revis women children health object studi evalu whether revis wic food packag associ various indic physic mental health women children

D063105;D000086382

T047;T064;T067;T057

36,324,107

predict valu fibrinogen occurr mild cognit impair event patient diabet peripher neuropathi research suggest fibrinogen fib relat mild cognit impair mci diabet peripher neuropathi dpn risk mci patient dpn great increas although studi evalu predict valu fib risk mci patient dpn

D003929;D003924;D060825

T047;T048

36,324,106

compar studi diseas burden attribut asbesto brazil china kazakhstan russia brazil china kazakhstan russia main asbesto produc countri form asbesto carcinogen human object studi estim diseas burden attribut asbesto major produc countri includ brazil china kazakhstan russia

D001194;D009369

T131;T197;T191

36,324,105

primipar women knowledg diastasi recti abdomini concern abdomin appear treatment perceiv abdomin muscl strength month postpartum cross section comparison studi diastasi recti abdomini dra preval condit postpartum period date scant knowledg dra influenc physic mental emot health studi investig primipar women knowledg dra concern abdomin appear perceiv abdomin muscl strength compar women without report dra

D017568;D000070630

T023;T190

36,324,104

accuraci spontan breath trial use combin cpap psv model predict extub outcom preterm infant preterm infant often requir mechan ventil howev object criteria predict outcom extub prematur neonat remain lack aim studi investig accuraci spontan breath trial sbt use combin model continu posit airway pressur cpap low level pressur support ventil psv predict extub outcom preterm infant gestat age week

D060666;D007235

T061;T047

36,324,103

effect oral motor facilit techniqu oral motor feed skill children cerebr palsi case studi defici oral motor function feed skill common children cerebr palsi cp oral motor therapi use method improv oral motor function feed skill oral motor facilit techniqu omft newli design comprehens oral motor therapi includ postur control sensori adapt breath control sensorimotor facilit direct feed

D002547

T019;T047

36,324,101

decision balanc attitud practic behavior predict factor relat experi advanc care plan taiwanes patient advanc cancer patient advanc cancer prone experi burdensom physic psycholog financi consequ healthcar provid may fulli appreci advanc cancer patient medic care autonomi embod advanc care plan acp may compromis qualiti end life eol henc essenti healthcar provid effect assess communic patient regard medic decis patient incapacit diseas progress purpos investig describ decision balanc attitud practic behavior acp predictor acp relat experi taiwanes patient advanc cancer

D032722;D010820;D009369

T058;T191;T097

36,324,100

effect omicron variant perinat outcom full term neonat research coronavirus diseas covid effect newborn ongo research specif variant effect none studi analyz effect omicron variant perinat outcom full term newborn omicron wave period method decemb april studi conduct newborn visit singl center investig due omicron matern infect matern pregnanc complic deliveri method birth week apgar score neonat resuscit program requir whether respiratori support requir h childbirth suspici infecti status mortal depend matern omicron infect

D000086382;D007232;D011248;D011251

T047;T046;T067

36,324,099

obes paradox among patient undergo total knee arthroplasti retrospect cohort studi obes recogn risk factor postop complic surgic patient howev recent studi show protect effect obes surgic non surgic patient studi examin associ bodi mass index bmi earli postop complic patient undergo total knee arthroplasti

D019645;D009767

T061;T047

36,324,098

investig role x chromosom inactiv androgen receptor cag repeat polymorph patient recurr pregnanc loss prospect case control studi previous research reveal skew x chromosom inactiv sxci androgen receptor ar cag polymorph associ increas risk recurr pregnanc loss rpl howev result conflict under mechan remain unclear studi investig role sxci ar cag polymorph patient rpl explor whether under mechan relat ovarian reserv preimplant embryo aneuploidi

D049951;D000026

T045;T047

36,324,097

secundipara follow fail vacuum deliveri factor associ success vagin deliveri histor prospect cohort studi focus deliveri subsequ fail vacuum deliveri fail vd secundipara object current studi examin factor associ vagin deliveri follow fail vd

D036861;D014620

T061

36,324,096

develop applic tfa macrosimul model case studi model impact tran fatti acid tfa elimin polici brazil consumpt tran fatti acid tfa direct associ cardiovascular diseas risk respons signific health burden global polici strategi reduc tfa includ limit content food elimin partial hydrogen oil pho market studi aim describ compar risk assess macrosimul model appli tool estim potenti reduct cvd mortal gain compar scenario tfa reductionelimin brazil

D044242;D003327

T168;T047

36,324,095

outcom prognost factor patient underw reoper persistentrecurr papillari thyroid carcinoma suitabl approach treat persistentrecurr papillari thyroid carcinoma ptc remain controversi reoper may consid effect method efficaci reoper patient locoregion persistentrecurr ptc especi unsatisfactori radioact iodin rai ablat result still uncertain studi aim clarifi clinic manag strategi locoregion persistentrecurr ptc explor factor may affect long term patient outcom reoper

D002291;D013964

T191

36,324,094

nomogram combin clinic factor biomark predict recurr high risk cutan squamous cell carcinoma although determin recurr cutan squamous cell carcinoma cscc import current suggest system singl biomark limit power predict recurr

D002294;D012878

T191

36,324,093

morpholog differ scoliosi curvatur caus difficulti earli detect base angl trunk inclin three dimension deform spine scoliosi specif given child regard number length curvatur degre rotat size curvatur angl earli diagnosi scoliosi clinic examin accord adam test depend correl angl trunk inclin ati cobb angl adopt diagnosi criterion aim studi demonstr need adopt differ diagnost criteria ati depend age locat scoliosi moreov observ differ aticobb correl becam basi propos introduc concept low medium high rotat curvatur clinic descript scoliosi

D012600

T047

36,324,091

cerebr blood flow abnorm central spare arteri spin label mild encephalopathi associ excitotox case report acut encephalopathi biphas seizur late reduc diffus aesd mild encephalopathi associ excitotox meex frequent acut encephalopathi pediatr patient japan aesd typic present biphas seizur delay reduc diffus subcort area call bright tree appear bta radiolog examin patient aesd arteri spin label asl show decreas cerebr blood flow cbf hyperacut stage increas cbf acut stage suggest use asl earli diagnosi aesd addit proton magnet reson spectroscopi mrs show elev glutam glu glutamin gln aesd meex group mild encephalopathi transient elev gln mrs similar aesd howev meex includ clinic biphas cours abnorm includ bta diffus weight imag although use asl aesd report report patient meex studi report experi year old girl diagnos meex show uniqu find asl

D001927;D003294

T047

36,324,089

understand rural urban dispar acut respiratori infect symptom among five children sub saharan africa multivari decomposit analysi acut respiratori infect ari account worldwid diseas burden children age five major occur sub saharan africa rural children vulner disproportion affect ari result examin rural urban dispar preval ari symptom associ factor among children age five sub saharan africa

D012141;D015362

T047

36,324,088

studi protocol transcrani electr stimul alpha frequenc appli rehabilit random control trial chronic stroke patient visuospati neglect frequent post stroke disord later attent visuospati neglect vsn vsn strong negat impact recoveri general independ daili life optim treatment deem urgent next tradit stroke treatment non invas brain stimul offer potenti facilit stroke recoveri complementari approach present studi visual scan train vst current convent treatment combin transcrani altern current stimul tac evalu addit effect repeat session tac combin six week vst rehabilit

D065908;D000071939;D010468;D020521

T061;T047;T048

36,324,087

nomogram predict cancer specif surviv elder patient gallbladd cancer gallbladd cancer gbc high aggress malign elder patient goal aim construct novel nomogram predict cancer specif surviv css elder gbc patient

D049451;D005706

T081;T170;T191

36,324,086

dementia risk predict individu mild cognit impair comparison cox regress machin learn model cox proport hazard regress model machin learn model wide use predict risk dementia exist comparison model most base empir dataset yield mix result studi examin accuraci various machin learn cox regress model predict time event outcom use mont carlo simul peopl mild cognit impair mci

D060825;D003704

T048

36,324,085

gmmchi gene express cluster use gaussian mixtur model cancer evolut consist stepwis acquisit genet epigenet chang alter gene express profil cell particular tissu result phenotyp alter act upon natur select recurr appear specif genet lesion across individu cancer cancer type suggest exist certain driver mutat like make major contribut tumor select advantag surround normal tissu respons consequenti aspect cancer cell gene express pattern phenotyp hypothes mutat like cluster specif dichotom shift express gene close control propos gmmchi python packag leverag gaussian mixtur model detect character bimod gene express pattern across cancer sampl tool analyz correl use conting tabl statist

D020869;D000465

T063;T170;T059

36,324,084

impact covid irish emerg depart ed cross section studi explor factor influenc ed utilis prior pandem patient perspect collater damag sar cov serious concern emerg medicin em communiti specif relat delay care increas morbid mortal attend unrel covid object studi describ profil patient attend irish ed prior pandem investig factor influenc ed utilis cohort

D058873;D000086382

T047;T067

36,324,083

evolut cbl cipk gene famili medicago genom wide character pervas duplic express pattern salt drought stress calcineurin b like protein cbls ubiquit ca sensor mediat plant respons various stress development process interact cbl interact protein kinas cipk cbls cipk play essenti role acclimat crop plant howev evolut two gene famili genus medicago poor understood

D055864;D010940

T070;T116

36,324,081

effect vari inhal oxygen concentr high flow nasal cannula oxygen therapi gastroscopi propofol sedat elder patient random control studi despit evid high flow nasal cannula oxygen therapi hfnc promot oxygen applic sedat gastroscopi elder patient receiv littl attent studi investig effect differ inhal oxygen concentr fio hfnc sedat gastroscopi elder patient

D015742;D000402;D012131

T121;T047;T046;T109

36,324,080

relationship genet risk score cardiometabol risk factor cross section studi eight decad cardiovascular diseas cvd remain lead caus death world cvd risk factor multifacet genet lifestyl play role aim studi investig associ genet profil risk score obes grs cardio metabol risk factor overweight obes women

D050177;D002318

T033;T047

36,324,078

chronic inflammatori demyelin polyneuropathi psoriasi comorbid signific allevi symptom secukinumab case report chronic inflammatori demyelin polyneuropathi cidp autoimmun diseas involv damag peripher nervous system cours diseas progress week frequent incid relaps remiss cours articl report rare combin cidp fluctuat symptom recurr remiss comorbid psoriasi

D020277;D011565

T047

36,324,077

immunomodulatori effect defensin macrophag induc immuno upregul antitumor function breast cancer macrophag mononuclear cd antigen present cell defens mechan play dual role tumor burden immunomodulatori antitumor function defensin still unclear despit accumul evid respons infect aim present studi elucid role defensin level ros cytokin chemokin express macrophag antitumor function breast cancer

D023083;D009369

T191;T116

36,324,076

recurr headach visual symptom young man rare neuron intranuclear inclus diseas case report neuron intranuclear inclus diseas niid progress neurodegen diseas patient niid may present heterogen clinic symptom includ episod encephalopathi dementia limb weak cerebellar ataxia autonom dysfunct among niid case report china patient often complic sever manifest therefor mani clinician consid diseas patient present relat minor complaint

D019636;D008881;D004827

T033;T047

36,324,075

retrospect analysi sar cov omicron invas delta french region status base multi variant model sar cov rapid spread diseas affect human life economi global scale diseas caus far million death omicron outbreak emerg botswana south africa spread around globe increas rate caus unpreced sar cov infect incid sever countri start decemb first omicron case report franc

D000086402;D000086382

T005;T067;T047

36,324,074

mitochondri genom analys provid new insight miss atp adapt evolut mytilida mytilida also known marin mussel wide distribut ocean worldwid member mytilida show tremend rang ecolog adapt speci distribut freshwat inhabit deep sea mitochondria play import role energi metabol might contribut adapt mytilida differ environ addit bivalv speci thought lack mitochondri protein code gene atp synthas f subunit increas studi indic absenc atp may caus annot difficulti atp gene character high diverg variabl length

D054629;D049879

T204;T028

36,324,073

multilay dynam perturb analysi method predict ligand protein interact ligand protein interact play key role defin protein function detect natur ligand given protein thus import bioengin task particular rapid develop ai base structur predict algorithm batch structur model high reliabl accuraci obtain low cost give rise urgent requir predict natur ligand base protein structur recent year although sever structur base method develop predict ligand bind pocket ligand bind site accur rapid method still lack especi predict ligand bind region spatial extens ligand pocket

D011506;D000465

T123;T170;T116

36,324,072

incid predictor acut kidney injuri among women sever pre eclampsia mbarara region referr hospit presenc acut kidney injuri aki pre eclampsia complic treatment includ increas length hospit stay need access servic like dialysi larg expens resourc limit set aim determin incid predictor acut kidney injuri among women sever pre eclampsia mbarara region referr hospit southwestern uganda

D011225;D004461;D058186

T047;T046;T037

36,324,070

aberr cytokeratin express hepatocyt predict ductopenia grade primari biliari cholang aberr cytokeratin express hepatocyt ck hs hallmark characterist cholestasi diseas especi ductopenia diseas primari biliari cholang pbc studi attempt evalu differ relationship clinic histolog featur aberr cytokeratin ck express hepatocyt pbc patient

D008105;D002779;D002761

T047

36,324,069

role bilirubin prognosi coronari arteri diseas relationship cardiovascular risk factor meta analysi bilirubin heme catabol product antioxid anti inflammatori anti apoptot properti implic prognosi sever diseas studi evalu prognost role bilirubin coronari arteri diseas cad patient

D003324;D009203

T047

36,324,067

histogram base analysi diffus weight imag predict aggress papillari thyroid carcinoma assess potenti appar diffus coeffici adc map predict aggress papillari thyroid carcinoma ptc base whole tumor histogram base analysi

D038524;D013964

T060;T191

36,324,066

zero augment beta prime model multilevel semi continu data bayesian infer semi continu data character excess proport zero right skew continu posit valu appear frequent medic research one exampl would pharmaceut expenditur pe data substanti proport subject investig may report zero two part mix effect model develop analys cluster measur semi continu data multilevel studi studi propos new flexibl two part mix effect model skew distribut nest semi continu cost data framework bayesian approach propos model specif consist two mix effect model link correl random effect part model occurr posit valu use general logist mix model part ii model magnitud posit valu use linear mix model model error follow skew distribut includ beta prime bp propos method illustr pharmaceut expenditur data multilevel observ studi analyt result report compar potenti model differ skew distribut simul studi conduct assess perform propos model dic lpml waic loo bayesian model select criteria measur diverg use compar model

D015233

T081;T170

36,324,064

teapv comprehens genom variat databas tea plant camellia sinensi genom variat play import role plant phenotyp model adapt evolut also enhanc popul genet divers regul gene express tea tree camellia sinensi larg genom gb make identif genom wide variant time consum expens continu public larg number differ type popul sequenc data lack open platform integr data identifi variant tea plant genometo integr genet variat confid tea plant popul genom whole genom resequenc transcriptom sequenc hybrid f individu total tb collect mutat site identif base variat inform construct first tea tree variat web servic databas teapv http http liushangtop support user search snp indel sv mutat ssrpolymorph ssr sequenc locat gene id furthermor websit also provid function gene express search differ transcriptom sequenc blast sequenc extract cds mutat loci etcth featur teapv databas make comprehens tea plant genet variat bioinformat platform research also help reveal new function mutat tea plant genom molecular marker assist breed

D028241

T002

36,324,063

speci genet divers relationship benthic macroinvertebr communiti along salin gradient speci genet divers chang parallel result speci genet divers correl sgdc rais question driver influenc biolog level divers sgdc either posit negat depend whether speci divers genet divers measur speci respond opposit way driver use tradit speci divers approach togeth ultra conserv element high throughput sequenc evalu sgdcs benthic macrofauna communiti baltic sea geolog young brackish water sea characteris steep salin gradient low speci rich assess sgdcs six focal marin invertebr speci differ taxonom group differ life histori ecolog function spatial tempor scale give comprehens insight communiti dynam young ecosystem extrins factor might drive sgdcs

D017753;D054712

T070;T034;T082