Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,348,363	function imag guid carbon ion irradi simultan integr boost local prostat cancer studi protocol phase ii random control clinic trial due physic dose distribut characterist bragg peak biolog effect kind high linear energi transfer ray heavi ion therapi advantag convent photon therapi efficaci safeti base evid prostat cancer lesion treatment common site tumor residu recurr treatment simultan integr boost radiat therapi prostat cancer proven advantag improv efficaci without increas toxic	D011471;D063193;D050397	T061;T191
36,348,362	impact profession midwiv mentor qualiti avail matern care govern sub district hospit bangladesh mix method observ studi studi compar govern sub district hospit bangladesh without global standard midwiv recent introduc midwiv without facil mentor see introduct midwiv associ improv qualiti avail matern care addit analys experi newli deploy midwiv matern staff manag join	D008427;D000071252;D008880	T065;T058;T091;T097
36,348,360	fatal overdos inject human growth hormon case report review literatur human growth hormon hgh categor perform enhanc substanc hgh abus athlet dope purpos	D019382;D004300;D012206;D006973	T121;T116;T125;T047;T046;T052
36,348,359	actual status drug price adjust factor drug price calcul analysi ultra orphan drug develop japan extrem high price facilit drug develop ultra rare diseas ultra orphan drug howev various problem aris term healthcar financ fair status ultra orphan drug price remain ambigu studi investig ultra orphan drug price japan relat drug examin relationship annual expect drug price expect sale expect number patient drug contain new activ ingredi therapeut use list nation health insur drug price list japan april august addit compar price drug price calcul method price calcul adjust factor ultra orphan drug	D016527;D009965	T081;T121;T058
36,348,358	adapt studi protocol evid base make better choic mbc multipl diet activ chang intervent rural appalachian popul rural appalachian resid experi among highest preval chronic diseas prematur mortal decreas life expect nation address grow inequ avoid duplic exist program necessit develop appropri adapt evid base lifestyl intervent yet publish articl explic accomplish contextu cultur adapt	D004032;D017216	T168;T058
36,348,357	apo alzheim diseas pathophysiolog therapeut strategi alzheim diseas ad common caus dementia worldwid preval rapid increas due extend lifespan among increas number genet risk factor identifi apolipoprotein e apo gene remain strongest preval impact half ad case allel apo gene signific increas ad risk allel protect relat common allel gene allel encod three apo protein isoform differ two amino acid posit primari physiolog function apo mediat lipid transport brain peripheri howev addit function apo divers biolog function recogn pathogen apo seed amyloid plaqu brain apo drive earlier abund amyloid apo isoform also differenti effect multipl relat independ pathway complex apo biolog pathobiolog present challeng design effect apo target therapeut strategi review examin key pathobiolog pathway apo relat target strategi specif focus latest technolog advanc tool	D000544	T047;T048
36,348,356	breast cancer subtyp northern thailand barrier satisfactori surviv outcom incid breast cancer bc thailand rise alarm rate annual incid bc thailand doubl span year retrospect studi conduct primari object assess compar surviv rate patient bc stratifi subtyp bc	D001943;D064726	T191
36,348,355	australian podiatrist understand current practic reablement older peopl qualit exploratori studi age australia popul place signific pressur health social age care servic due increas demand provis relat decreas healthcar workforc reablement introduc australian commonwealth govern aim increas older peopl independ age place decreas depend age care servic date research reablement practic focuss intervent physiotherapist occup therapist nurs data avail podiatrist involv aim research explor australian podiatrist understand current practic implement reablement approach older client	D011032;D059825	T091;T097
36,348,354	cortic screw placement spinous process clamp guid cadav studi access accuraci cortic bone trajectori cbt techniqu provid altern method fixat lumbar spine patient osteoporosi accuraci cbt screw placement could improv mechan stabil reduc complic rate	D065289;D013123	T061;T074
36,348,353	collect peripher blood mononucl cell chronic graft versus host diseas immunolog research safeti effect leukapheresi patient chronic graft versus host diseas gvhd major caus late morbid non relaps mortal recipi allogen hematopoiet cell transplant hct biolog howev remain poor understood make studi biolog immunomodulatori therapi difficult task research often hamper lymphopenia common patient preclud studi critic cellular subset across spectrum sever diseas studi explor potenti leukapheresi safe acquir effici store immun cell immunolog research chronic gvhd	D006086;D018380	T061;T047
36,348,352	plan patient specif instrument intraarticular correct osteotomi trapeziometacarp metacarp finger joint intra articular malunion finger lead deform loss function treat intra articular correct osteotomi aim studi evalu radiograph joint congruenc feasibl function outcom three dimension print patient specif instrument psi correct osteotomi trapeziometacarp finger joint	D017759;D050279	T023;T046;T037
36,348,351	caf deriv scube promot malign stem shhgli pathway hepatocellular carcinoma tumour microenviron cirrhot liver excel sourc cancer associ fibroblast caf particip carcinogenesi thus import clarifi crosstalk caf hcc cell relat mechan regul carcinogenesi	D006528;D000072645;D008113	T191;T025
36,348,350	elev spermin remodel immunosuppress microenviron drive modif pd l hepatocellular carcinoma spermin frequent elev tumor tissu bodi fluid cancer patient critic cancer cell prolifer migrat invas howev immun function spermin hepatocellular carcinoma progress remain unknown present studi aim elucid immunosuppress role spermin hepatocellular carcinoma explor under mechan	D006528;D008113	T191
36,348,349	effect qigong exercis physic mental health colleg student systemat review meta analysi physic mental health problem becom serious among colleg student due lifestyl chang increas academ stress qigong exercis regard potenti effect intervent improv physic mental health colleg student	D064906	T061
36,348,348	effect pharmacolog treatment outcom heart failur preserv eject fraction updat systemat review network meta analysi random control trial optim treatment strategi patient heart failur preserv eject fraction hfpef remain uncertain goal studi compar treatment effect differ therapeut agent patient hfpef	D000077203;D006333	T121;T047;T046;T109
36,348,347	interplay pandem season paramet dental emerg servic evalu relationship pandem event dental emerg servic frequent util pattern scope covid pandem analyz consid regard season paramet	D058873;D000086382	T047;T067
36,348,346	conduct support oncolog clinic trial covid pandem challeng strategi coronavirus diseas covid pandem result sever interrupt clinic research worldwid global public health crisi requir investig research rapid develop implement new strategi solut mitig negat impact progress clinic trial paper describ challeng strategi lesson learn regard continu support oncolog clinic trial pandem hope provid insight implement clinic trial public health emerg better prepar futur instancestri registr clinicaltrialsgov servic us nation institut health nct regist januari	D000086382;D009369	T047;T191;T067
36,348,345	vicari trauma hemodialysi healthcar worker besieg ethiopia tigray region call action war ethiopia tigray broke novemb amid arm conflict government institut destroy peopl displac thousand civilian kill region experienc type blockad sinc war broke june time feder govern ethiopia impos sieg cut region rest world due shortag medicin medic suppli wit death otherwis prevent normal condit becom daili predica healthcar worker burden healthcar disintegr particular carri patient chronic medic ill includ patient dialysi	D000068376	T048
36,348,344	autolog micro fragment adipos tissu associ arthroscopi moder sever knee osteoarthr outcom two year follow adipos tissu recent gain grow interest treatment osteoarthr oa aim present studi evalu efficaci singl inject autolog micro fragment adipos tissu amfat associ arthroscopi cartilag debridementmenisc regular select meniscectomymicro drill symptomat knee oa	D020370	T047
36,348,343	exercis train attenu pulmonari inflamm mitochondri dysfunct mous model high fat high carbohydr induc nafld non alcohol fatti liver diseas nafld lead pulmonari dysfunct associ pulmonari inflamm moreov littl known regard therapeut role exercis train pulmonari pathophysiolog nafld present studi aim investig effect exercis train high fat high carbohydr hfhc induc pulmonari dysfunct cbl mice	D065626;D011014	T047;T050
36,348,342	aberr interhemispher function connect major depress disord without anhedonia anhedonia core featur major depress disord mdd subtyp depress mdd anhedonia may except neurobiolog mechan howev neuropatholog anhedonia mdd remain unclear thus studi aim investig brain function differ mdd without anhedonia	D003865	T048
36,348,341	whole genom sequenc analysi reveal circul multipl sar cov variant concern nairobi neighbor counti kenya march juli emerg rapid spread sar cov variant concern voc link new wave covid epidem occur differ region world voc acquir adapt mutat enhanc virus transmiss increas virul reduc respons neutral antibodi kenya experienc six wave covid epidem studi analyz genom sequenc sar cov strain circul nairobi neighbor counti kenya march juli viral rna extract rt pcr confirm covid case follow sequenc use artic network protocol oxford nanopor technolog analysi sequenc data perform use differ bioinformat method analys reveal studi period three sar cov variant concern voc circul nairobi nearbi counti kenya alpha b lineag predomin follow delta b beta b notabl alpha b voc frequent march may delta b domin begin june juli sequenc comparison reveal kenyan virus genet similar circul region although major kenyan virus cluster togeth respect phylogenet lineagesclad signific number interspers among foreign strain march juli studi find indic preval multipl lineag sar cov voc nairobi nearbi counti kenya data suggest recent increas sar cov infect particular nairobi kenya whole attribut introduct communiti transmiss sar cov voc among populac conclus find provid snapshot sar cov variant circul kenya studi period	D000086402;D000086382	T005;T067;T047
36,348,340	evalu novel obes lipid relat indic predictor abnorm glucos toler chines women polycyst ovari syndrom aim evalu perform chines viscer adipos index cvai viscer adipos index vai lipid accumul product lap triglycerid glucos tyg indic screen abnorm glucos toler agt chines women polycyst ovari syndrom pcos use oral glucos toler test ogtt refer test addit essenti compar abil indic bodi mass index bmi waist circumfer wc fast plasma glucos fpg	D011085;D007333;D018149	T047;T046
36,348,339	requir challeng hospit dashboard systemat literatur review today use data administr clinic process quit challeng due larg volum data data collect various sourc lack data structur data manag tool dashboard play import role time visual display critic inform key perform	D006761	T073;T093
36,348,338	risk factor natur menopaus age evid two british popul base birth cohort studi menopaus occur age medic induc refer earli natur menopaus affect around one women serious health consequ consequ includ increas risk caus mortal cardiovascular diseas osteoporosi type diabet	D003924;D008594	T047
36,348,337	hitim hierarch tumor immun microenviron epigenet deconvolut accur cell type resolut tumor microenviron use tumor type specif dna methyl data cellular composit solid tumor microenviron heterogen vari across patient tumor type high resolut profil tumor microenviron cell composit crucial understand biolog clinic implic previous tumor microenviron gene express dna methyl base deconvolut approach shown deconvolv major cell type howev exist method lack accuraci specif tumor type includ limit identif individu cell type	D019175;D009369	T191;T044
36,348,336	development dispar sedentari time period day among us youth cross section studi definit evid show sedentari time st independ risk factor chronic diseas irrespect physic activ despit call limit youth st studi demonstr spike st transit childhood adolesc identifi period day eg school school afterschool even st higher adolesc vs children specifi within daili routin st dispar emerg may import inform intervent strategi period day correspond variat set supervis purpos studi examin devic assess st engag period day development stage nation repres sampl unit state youth	D057185;D061725	T033;T060;T079
36,348,335	oral hygien oral health behavior periodont complaint oral health relat qualiti life pregnant women questionnair base cross section studi aim evalu oral hygien oral health behavior periodont complaint oral health relat qualiti life ohrqol pregnant women southwest saxoni germani	D011788;D009910	T078;T055
36,348,334	comparison magnet reson imag electr imped myographi evalu lumbar skelet muscl composit compar electr imped myographi eim mri assess lumbar skelet muscl composit	D018482;D008161	T023;T029;T024
36,348,333	trend chang factor analysi endometri hyperplasia patient polycyst ovarian syndrom base korean nation health insur databas polycyst ovari syndrom pcos common endocrin disord associ increas risk gynecolog disord endometri hyperplasia eh howev substanti factor comorbid eh pcos remain investig analyz trend chang pcos factor relat comorbid pcos eh use data korea nation health insur knhi claim databas	D011085;D004714;D003924	T047
36,348,332	use video consult support orthoped patient treatment interfac clinic general practition video consult proven power support tool patient doctor interact general covid pandem studi analyz feasibl use orthoped telemed consult otc orthoped patient interfac clinic general practition	D058005;D000086382;D017216	T047;T067;T058;T097
36,348,331	chondromalacia patella increas risk herp zoster popul base studi reactiv herp zoster hz associ diseas stress howev relationship chondromalacia patella cmp hz remain poor understood studi investig relationship cmp risk develop hz	D006562;D002357	T047
36,348,330	fals certainti acquisit anatom physiotherapeut knowledg effici metacognit monitor monitor one thought process specif one state knowledg essenti effect clinic reason know one know compet student health profess need develop student often tend develop fals certainti knowledg longer cours educ time frame requir effect occur remain unclear investig whether student develop fals certainti alreadi one cours unit	D013337;D000067489	T041;T097
36,348,329	polyphenol conyza dioscoridi l amelior alzheim diseas like alter multi target activ two anim model recent investig suggest anticanc agent may inhibit progress alzheim diseas ad patholog conyza dioscoridi l demonstr anticanc antioxid anti inflammatori antidiabet effect studi carri investig efficaci polyphenol conyza dioscoridi l extract pcde ad	D000544;D035401;D019659;D003924	T047;T002;T048
36,348,328	elev serum triglycerid level may key independ predict factor gallbladd cancer risk gallbladd stone diseas patient case control studi gallbladd stone diseas gsd main risk factor gallbladd cancer gbc studi aim reveal bridg metabol syndrom	D007333;D024821;D005706;D015228	T047;T046;T191
36,348,327	lower transmiss sar cov among asymptomat case evid contact trace data oslo norway asymptomat covid case complic surveil track pandem previous studi estim infecte remain asymptomat	D000086402;D000086382	T005;T067;T047
36,348,326	effect ai assist softwar inter intra observ variabl x ray bone age assess preschool children rapid develop deep learn algorithm rapid improv comput hardwar past year ai assist diagnosi softwar bone age achiev good diagnost perform purpos studi investig effect ai assist softwar resid inter observ agreement intra observ reproduc x ray bone age assess preschool children	D012984;D001185	T090;T170;T073;T066
36,348,325	vitamin level among children adolesc adult elder pakistani popul cross section studi vitamin essenti part healthi diet also known sunshin hormon help absorb calcium phosphat within bodi essenti develop teeth bone grow children defici vitamin caus weak bone osteoporosi older individu osteomalacia children also caus loss alveolar bone around teeth increas dental caviti problem associ gum diseas caus depress fatigu appetit loss studi aim observ vitamin defici insuffici suffici among children adult adolesc elder pakistani popul	D014807;D014808	T121;T047;T127
36,348,324	perceiv barrier toward import applic medic research sourc gender dispar among medic undergradu littl known gender dispar among medic undergradu develop world therefor studi aim explor attitud perceiv barrier among jordanian medic student particular women	D013337;D035843	T062;T097
36,348,323	second opinion opportun declin patient typolog experi regard decis make process preced elect surgeri germani address problem overus elect surgeri support patient decis make process second opinion direct introduc germani enabl patient statutori health insur obtain second opinion certain surgic indic studi aim identifi base experi patient undergon elect surgeri role seek second opinion reach decis	D003657;D017558	T061;T041
36,348,322	genom wide identif analysi bzip gene famili reveal role develop drought stress wheel wingnut cyclocarya paliurus bzip gene famili import role various biolog process includ develop stress respons howev littl inform gene famili avail wheel wingnut cyclocarya paliurus result studi identifi bzip gene c paliurus genom analyz phylogenet relationship chromosom locat gene structur collinear gene express profil bzip gene could divid group uneven distribut among c paliurus chromosom analysi cis regulatori element indic bzip promot associ phytohormon stress respons express pattern bzip gene leav differ among development stage addit sever bzip member differenti express drought stress express pattern verifi rt qpcr	D055864;D018506	T045;T070
36,348,321	molecular character phylogenet analysi porcin epidem diarrhea virus strain circul china porcin epidem diarrhea virus pedv enter coronavirus becom major causat agent acut gastroenter piglet sinc china	D053485;D013553;D018352	T005;T047
36,348,320	teach card low cost brief materi teach basic life support year old primari school children quasi experiment combin design studi teach basic life support bls school key initi improv surviv rate hospit cardiac arrest low cost train materi reach wider popul aim compar effect use teach card tradit instructor led combin method bls skill attitud evalu long term effect two month	D016887	T061
36,348,318	rapid precis identif bloodstream infect use pre treatment protocol combin high throughput multiplex genet detect system bloodstream infect bsi life threaten condit high morbid mortal rate worldwid earli diagnosi bsi critic avoid unnecessari applic antimicrobi agent proper treatment howev current standard method base blood cultur time consum thus fail provid time etiolog diagnosi bsi common pcr base detect might inhibit matrix compon	D016470;D018805;D003141	T047;T046
36,348,317	differenti properti kras transvers transit mutat non small cell lung cancer associ environment factor clinic outcom kras mutat non small cell lung cancer nsclc account nsclcs white patient east asian respect therefor regard major therapeut target howev epidemiolog clinic characterist fulli elucid wide varieti mutat subtyp focus two distinct base substitut type transvers mutat transit mutat well associ environment factor clinic outcom	D002289;D008175	T191
36,348,316	lost explan intern conflict discours adhd psychoeduc psychiatr classif understood mani differ way children adhd parent psychoeduc import sourc inform shape understand moreov psychoeduc often taken children parent repres stori understood therapist result way psychoeduc formul may affect therapeut allianc one robust mediat treatment outcom addit psychoeduc may indirect influenc way understand psycholog differ societi	D001289	T048
36,348,315	bodi mass index incid lung cancer hunt studi use observ mendelian random approach tradit observ studi shown invers associ bodi mass index bmi lung cancer risk mendelian random mr analysi use genet variant instrument bmi may clarifi natur associ	D008175;D000230;D000077192	T191
36,348,314	technolog free predictor preterm birth singleton women threaten preterm labor prospect cohort studi predict preterm birth still challeng due multipl etiolog prospect cohort studi aim determin technolog free predictor preterm birth singleton women threaten preterm labor	D047928;D007752	T046
36,348,313	effect behavior therapi base counsel anxious mother infant colic random control clinic trial given possibl effect matern anxieti sever colic pain infant studi aim investig effect behavior therapi counsel infantil colic primari outcom matern anxieti mother infant attach secondari outcom anxious mother colicki infant	D003085	T033;T184
36,348,312	enterovirus detect differ region madagascar reveal higher abund enterovirus speci c area sever outbreak vaccin deriv poliovirus occur poliomyel outbreak due pathogen vaccin deriv poliovirus vdpvs threaten complic global polio erad initi vdpvs genet recombin non polio enterovirus npev speci c littl known factor favor genet macroevolut process sinc madagascar experienc sever outbreak poliomyel due vdpvs vdpvs isol south island current studi explor viral factor promot explain emerg recombin vdpvs madagascar	D017955;D004770;D004769;D011051;D030015;D023321	T129;T121;T109;T005;T047
36,348,311	patient ectop acth syndrom might better prognosi bronchopulmonari carcinoid lymph node metastasi receiv radic surgeri singl centr retrospect studi last year china bronchopulmonari carcinoid bpcs rare malign known one common caus ectop adrenocorticotrop hormon acth syndrom surgeri mainstay therapi one key question consid surgic treatment impact local lymph node metastas sought determin risk factor prognosi ln metastas resect carcinoid patient	D000182;D002276	T047;T191
36,348,310	design feasibl implement strategi address chaga guidelin engag focus attend women childbear age children primari healthcar level argentina pilot studi chaga public health problem especi latin america exacerb migratori movement increas urban argentina among countri highest estim preval region peopl infect mother child main mode transmiss vertic transmiss signific reduc treat women childbear age sever guidelin region recommend treatment primari prevent strategi child secondari prevent strategi women famili despit recommend women childbear age alway treat children receiv time diagnosi treatment object research design implement strategi improv use chaga guidelin focus attend women childbear age children primari healthcar level pilot three primari health care center argentina	D058873;D000086382	T047;T067
36,348,309	comparison supervis exercis therapi without biopsychosoci approach chronic nonspecif low back pain random control trial biopsychosoci rehabilit recommend chronic nonspecif low back pain cnlbp howev effect compar tradit supervis exercis therapi cnlbp treatment still unclear	D017116;D059350	T184;T047
36,348,308	two case infantil onset primari general glucocorticoid hypersensit effect mifepriston primari general glucocorticoid hypersensit pggh rare diseas caus termin organ hypersensit glucocorticoid aetiolog unknown incid pggh extrem rare especi children date literatur etiolog prognosi treatment pggh scarc aim studi describ case two chines children infantil onset pggh one famili one die one treat mifepriston two youngest children pggh report literatur	D003480;D006967	T047;T046
36,348,307	effect evalu kangaroo mother care lipe area guizhou provinc china kangaroo mother care kmc refer mother babi birth earli start continu skin contact way newborn care simpl oper easi control low cost larg high consumpt equipmentso suitabl develop area medic resourc relat scarc guizhou provinc relat poor provinc china mani ethnic minor	D060127	T061
36,348,306	fat storag induc transmembran protein beyond mediat lipid droplet format fat storag induc transmembran protein fitm initi identifi member conserv endoplasm reticulum er resid transmembran protein gene famili found involv lipid droplet ld format recent sever studi demonstr abil fitm direct bind triglycerid diacylglycerol diphosphatas activ hydrolyz fatti acyl coa might enabl fitm maintain format lipid droplet engag lipid metabol protect cellular stress base distribut fitm tissu import role lipid droplet biolog lipid metabol discov fitm close relat muscl develop adipocyt differenti energi metabol accord abnorm express fitm associ type diabet lipodystrophi also cardiac diseas sever type cancer studi review structur distribut express regul function fitm potenti relationship various metabol diseas hope provid inspir fruit research direct applic fitm protein moreov review provid import theoret basi applic fitm diagnosi treatment relat diseas	D066292;D003924	T026;T047
36,348,305	mir p suppressor colorect cancer earli stage promot colorect cancer metastasi late stage regul akt signal evok emt mediat anoiki mir p general consid tumor suppressor earli stage colorect cancer regul occur progress later stage associ metastasi indic mir p may play dual role colorect cancer crc explor detail mechan mir p carcinogen import	D035683;D015179	T123;T191;T114
36,348,304	effect pregnanc discrimin postpartum depress symptom follow studi pregnanc discrimin workplac preval worldwid howev studi examin effect pregnanc discrimin mother perinat mental health aim investig associ pregnanc discrimin postpartum depress symptom mediat effect prenat depress symptom associ	D019052	T048
36,348,303	carpal tunnel syndrom secondari tumor calcinosi case report review literatur carpal tunnel syndrom cts preval peripher nerv entrap diseas pathophysiolog multifactori defin idiopath case present rare case cts secondari tumor calcinosi search english literatur present detail publish case entiti	D002349;D002114	T047;T046
36,348,301	interpret dic risk predict model base convolut neural network time seri data dissemin intravascular coagul dic complex life threaten syndrom associ end stage differ coagul disord earli predict risk dic develop urgent clinic need reduc advers outcom howev effect approach model identifi earli dic still lack studi novel interpret deep learn base time seri use predict risk dic studi cohort includ icu patient bed academ hospit januari januari experiment result show model achiev excel perform auc accuraci f gradient weight class activ map grad cam use explain predict model identifi patient dic decis basi model display form heat map model use identifi high risk patient dic earli help earli intervent dic patient improv treatment effect	D004211	T047
36,348,300	public knowledg dementia risk reduct norway sever modifi lifestyl risk factor dementia identifi unclear much norwegian public know relationship lifestyl brain health therefor studi aim investig knowledg modifi dementia risk protect factor belief attitud toward dementia dementia risk reduct random select subsampl norwegian popul	D003704;D003920	T047;T048
36,348,299	autom classif protein express level immunohistochemistri imag improv detect cancer biomark express chang protein associ cancer progress use biomark cancer diagnosi autom system frequent appli larg scale detect protein biomark provid valuabl complement wet laboratori experi exampl previous work use immunohistochem imag base machin learn classifi protein subcellular locat screen biomark protein chang locat colon cancer tissu tool could recogn locat biomark consid effect protein express level chang screen process	D014408;D009369	T123;T191
36,348,298	investig public awar prevail attitud percept toward domest violenc abus unit kingdom qualit studi report case domest violenc abus dva increas sinc advent covid pandem ensu lockdown understand general public view dva vital would help develop target intervent effect public polici tackl rise problem societi qualit studi investig public awar attitud percept toward dva explor mechan tackl dva communiti set uk	D000086382;D017579	T054;T047;T067;T048
36,348,297	pathogenesi plant associ pseudomona aeruginosa caenorhabd elegan model pseudomona aeruginosa global dread pathogen trigger fatal immuno compromis individu agricultur ecosystem massiv reservoir bacterium sever studi recommend p aeruginosa promot plant growth howev limit attempt evalu health risk associ plant associ p aeruginosa current studi hypothes agricultur p aeruginosa strain exhibit eukaryot pathogen despit plant benefici trait	D011550;D011552	T047;T007
36,348,296	preval sleep relat problem risk communiti dwell older adult popul cross section survey base studi despit evid advers health consequ inadequ restor sleep older adult assess sleep quantiti qualiti use sleep aid routin done aim character sleep problem sleep risk advic receiv sleep communiti dwell older adult popul overal subgroup health condit function difficulti	D007319;D000163;D012893;D020181	T184;T047;T048
36,348,295	descript comparison postop function patient hip fractur rebro univers hospit compar cross section studi hip fractur global problem probabl increas hip fractur impair health aspect creat demand postop care studi describ compar patient hip fractur increas knowledg group could basi optim aftercar dimens rehabilit	D018737;D006620	T081;T040;T037
36,348,294	serum marker ct characterist coronari calcifi nodul assess intravascular ultrasound calcifi nodul cn type potenti vulner plaqu format mechan remain unknown studi assess serum marker comput tomographi angiographi cta characterist cn valid intravascular ultrasound ivus	D058226;D003324;D002114	T047;T046;T020;T031
36,348,293	distribut induc characteris prophag latilactobacillus sakei lactic acid bacteria lab use starter wide varieti food ferment number report phage infect lab steadili increas year inform phage associ latilactobacillus sakei frequent use meat starter remain scarc	D039002;D001435	T005
36,348,292	low dose nivolumab advanc hepatocellular carcinoma approv dose nivolumab mgkg flat dose mg indic dose respons relationship nivolumab therefor low dose regimen may option reduc financi toxic studi design investig efficaci safeti low dose nivolumab manag hepatocellular carcinoma hcc	D006528;D008113;D006526	T047;T191
36,348,290	function mri radiom base assess pelvic bone marrow chang concurr chemoradiotherapi cervic cancer quantifi dose respons relationship chang pelvic bone marrow pbm function mr radiom featur rf concurr chemoradiotherapi ccrt patient cervic cancer establish correl hematolog toxic provid basi pbm spare	D002583;D050397	T061;T191
36,348,289	develop verif nomogram predict prognosi resect gastric cancer outlet obstruct prognosi patient gastric cancer gc gastric outlet obstruct goo gastrectomi high variabl studi aim develop nomogram predict prognosi patient	D013274;D017219	T047;T191
36,348,288	x box bind protein key modul heal endotheli cell novel ec phenotyp promot angiogenesi mcao endotheli cell ec play import role angiogenesi vascular reconstruct pathophysiolog ischem stroke previous investig provid profound cerebr vascular atlas physiolog condit fail identifi new diseas relat cell subtyp aim identifi new ec subtyp determin key modul gene	D042783;D020244	T047;T020;T025
36,348,287	reproduc repeat semi autom pipelin quantifi trapeziometacarp joint angl use dynam comput tomographi trapeziometacarp tmc joint mechan complex joint common affect musculoskelet diseas osteoarthr quantifi vivo tmc joint biomechan joint angl tradit reflect marker base method difficult due joint locat hand dynam comput tomographi ct facilit quantif tmc joint motion continu captur three dimension volum time howev post process dynam ct dataset time intens autom method need reduc process time allow applic larger clinic studi purpos work introduc fast semi autom pipelin quantifi joint angl dynam ct scan tmc joint evalu associ error joint angl translat comput mean reproduc repeat studi	D013933;D014057	T060;T023
36,348,286	effect increas lp follow statin therapi cardiovascular prognosi secondari prevent popul coronari arteri diseas lipoprotein lp independ risk factor coronari arteri diseas cad recent studi indic statin tend increas lp level howev associ statin mediat increas lp level cad determin method studi includ patient acut coronari syndrom ac underw percutan coronari intervent pci lp level measur baselin month statin therapi studi endpoint major advers cardiovascular event mace hazard ratio mace adjust potenti confound use cox regress	D003324;D019161;D062645	T061;T121;T047;T109
36,348,284	short form develop specif modul qlicd crf v assess qualiti life patient chronic renal failur short instrument would enhanc viabil studi therefor aim shorten specif modul spd qualiti life instrument chronic diseas chronic renal failur qlicd crf assess qualiti life patient chronic renal failur	D011788;D007676	T078;T047
36,348,283	correl galectin rdw hepc hs ferritin prognosi patient acut onset chronic heart failur chronic heart failur chf character high hospit rate high mortal rate particular import identifi biomark predict prognosi patient acut attack chf	D037502;D006333	T129;T047;T046;T116
36,348,282	diabet retinopathi corneal endotheli paramet analyt cross section studi investig possibl associ differ pattern diabet retinopathi dr corneal endothelium cell type diabet mellitus patient	D003930;D003924	T047
36,348,281	collect encod protein properti enrich protein languag model pre train natur languag process model larg natur languag corpus natur transfer learn knowledg protein domain fine tune specif domain task howev studi focus enrich protein languag model joint learn protein properti strong correl protein task elabor design multi task learn mtl architectur aim deciph implicit structur evolutionari inform three sequenc level classif task protein famili superfamili fold consid co exist contextu relev human word protein languag employ bert pre train larg natur languag corpus backbon handl protein sequenc import encod knowledg obtain mtl stage well transfer fine grain downstream task tape experi structur evolut relat applic demonstr approach outperform mani state art transform base protein model especi remot homolog detect	D009323;D011506	T123;T116;T066
36,348,280	cranium quasi experiment studi improv metabol screen hiv test communiti mental health clinic compar usual care individu serious mental ill often receiv guidelin concord metabol screen human immunodefici virus hiv test contribut increas morbid prematur mortal studi evalu effect cranium cardiometabol risk assess treatment novel integr model underserv popul mental ill intervent increas metabol screen hiv test among patient serious mental ill communiti mental health clinic compar usual care	D008603;D015658	T047;T041
36,348,279	phylogenet analysi stress respons plant u small nuclear ribonucleoprotein b gene famili altern splice import channel gene express regul protein diversif addit major reason consider differ number gene protein eukaryot plant u small nuclear ribonucleoprotein b ub compon splice complex u snrnp play import role current studi investig plant ub mechan remain unclear	D017413;D017381	T026;T123;T116
36,348,278	stereotact bodi radiat therapi effect local treatment advanc hepatocellular carcinoma patient inferior vena cava right atrial tumor thrombus aim studi evalu curat effect safeti stereotact bodi radiat therapi sbrt treat hepatocellular carcinoma hcc patient inferior vena cava ivctt right atrial tumor thrombus ratt	D006528;D016634;D008113;D013927	T061;T191;T046
36,348,277	phylogenom analysi develop molecular marker determin twelv plum cultivar prunus rosacea plum one import econom crop rosacea famili produc world china mani local varieti genom inform limit genet studi first sequenc assembl analyz plastom twelv plum cultivar develop molecular marker distinguish	D000068242;D027861;D027824	T168;T002
36,348,276	pyridostigmin reduc mortal patient sever sar cov infect phase random control trial respiratori failur sever coronavirus diseas covid associ sever inflammatori respons acetylcholin ach reduc system inflamm experiment bacteri viral infect pyridostigmin increas half life endogen ach potenti reduc system inflamm aim determin pyridostigmin decreas composit outcom invas mechan ventil imv death adult patient sever covid	D000086382	T047;T067
36,348,275	associ live arrang cognit declin older adult nation repres longitudin studi china live arrang critic surviv well older peopl especi china filial pieti cultur demand adult children care serv parent studi aim explor associ live arrang cognit declin among older peopl china	D012111;D060825	T078;T082;T083;T033;T056;T096;T081;T048
36,348,274	fadd key molecular player cancer progress cancer lead diseas relat caus death worldwid despit advanc therapeut intervent cancer remain major global public health problem cancer pathogenesi extrem intric larg unknown fas associ protein death domain fadd initi identifi adaptor protein death receptor mediat extrins apoptosi recent evid suggest fadd play vital role non apoptot cellular process prolifer autophagi necroptosi fadd express activ modul complic network process dna methyl non code rna post translat modif fadd dysregul shown close associ pathogenesi numer type cancer howev detail mechan fadd dysregul involv cancer progress still fulli understood review main summar recent find structur function regulatori mechan fadd focus role cancer progress clinic implic fadd biomark therapeut target cancer patient also discuss inform review herein may expand research understand fadd contribut develop fadd base therapeut strategi cancer patient	D017209;D009369	T123;T191;T116;T043
36,348,273	associ chang depress symptom hip fractur among middl age older chines individu prospect cohort studi although studi shown depress symptom associ increas risk hip fractur hf depress symptom dynam unclear whether hf risk persist depress symptom remit studi aim examin associ chang depress symptom hf risk	D003863;D012179	T033;T184;T048
36,348,272	breeder prevent pathogen adapt select increas resist infecti diseas recent research show genet select high potenti reduc preval infecti diseas livestock howev like intervent target infecti diseas genet select livestock exert select pressur pathogen popul select pathogen may lead escap strategi reduc effect select livestock diseas resist thus success breed livestock lower diseas preval essenti develop strategi prevent invas pathogen mutant escap host resist investig condit escap mutant replac wild type pathogen close livestock popul use mathemat model diseas transmiss	D058751;D003141	T047;T008
36,348,271	multipl instanc neural network base spars attent cancer detect use cell receptor sequenc earli detect cancer much explor due paramount import biomed field among differ type data use answer biolog question studi base cell receptor tcrs recent spotlight due grow appreci role host immun system tumor biolog howev one mani correspond patient multipl tcr sequenc hinder research simpli adopt classic statisticalmachin learn method recent attempt model type data context multipl instanc learn mil despit novel applic mil cancer detect use tcr sequenc demonstr adequ perform sever tumor type still room improv especi certain cancer type furthermor explain neural network model fulli investig applic articl propos multipl instanc neural network base spars attent minn sa enhanc perform cancer detect explain spars attent structur drop uninform instanc bag achiev interpret better predict perform combin skip connect experi show minn sa yield highest area roc curv score averag measur across differ type cancer compar exist mil approach moreov observ estim attent minn sa identifi tcrs specif tumor antigen cell repertoir	D016571;D009369	T170;T191
36,348,269	bone marrow mesenchym stem cell deriv exosom shuttl mir p allevi mechan allodynia rat target notch microglia studi probe function mechan bone marrow mesenchym stem cell bmsc deriv exosom load mir p mechan allodynia	D055354;D035683;D059630	T026;T123;T025;T114
36,348,268	discuss caus thrombolysi failur patient stemi case report spontan coronari arteri dissect scad emerg increas diagnos caus st segment elev myocardi infarct stemi easili miss delay effect use coronari angiographi cag advanc intracoronari imag examin stemi patient led increas detect scad	D000072657;D000086382;D009203	T047;T067
36,348,267	cna correl consensus base cross taxonomi network analysi composit microbi data studi co occurr network structur microbi sampl one critic approach understand perplex delic relationship microb host diseas also critic develop tool investig co occurr network differenti abund analys reveal diseas relat taxa taxa relationship addit also necessari tighten co occurr network smaller modul increas abil function annot interpret taxa taxa relationship also critic retain phylogenet relationship among taxa identifi differenti abund pattern use resolv contradict function report differ studi	D010802	T062;T078
36,348,266	attenu virul resist superbug staphylococcus aureus bacteria isol neonat sepsi ascorb acid dexamethason sodium bicarbon infect affect neonat caus staphylococcus aureus widespread healthcar facil henc novel strategi need fight pathogen studi aim investig effect fda approv medic ascorb acid dexamethason sodium bicarbon reduc virul resist staphylococcus aureus bacteria caus neonat sepsi seek suitabl altern problem multi drug resist	D055624;D000071074;D013203	T047;T007
36,348,202	predat capac bradymonabacteria recent discov group order bradymonadal isol marin sediment bacteri predat vital feed behavior affect communiti structur maintain biodivers howev predatori bacteri speci coastal sediment compar poor describ studi predat capac nine cultur bradymonabacteria strain belong recent discov order bradymonadal determin differ type prey predatori effici bradymonabacteria increas initi prey proport mix cultur decreas initi prey proport number surviv prey bacteri cell signific decreas h predat bradymonabacteria strain tmq seh b fa howev growth prey strain occur presenc bradymonabacteria strain tmq tmq tmq v yn initi prey proport decreas bradymonabacteria strain prey effici furthermor establish neighbor coloni prey destroy bradymonabacteria invad predat capac determin predat abil strain motil agar surfac find provid new insight potenti ecolog signific predatori bradymonabacteria may serv potenti probiot use aquacultur	D011235;D020564	T007;T054
36,348,172	f bzip regul zn defici respons land plant review describ zinc sens transcript regul zinc defici respons arabidopsi discuss evolutionari conserv land plant facilit translat approach improv zn nutrit valu crop speci zinc essenti micronutri live organ due presenc larg number protein structur catalyt cofactor plant zinc homeostasi mechan compris uptak soil transport distribut throughout plant provid adequ cellular zinc avail discuss transcript regul respons zinc defici zinc sens mechan arabidopsi evolutionari conserv land plant arabidopsi f group basic region leucin zipper f bzip transcript factor bzip bzip function simultan sensor intracellular zinc status direct bind zinc ion central regul zinc defici respons target gene includ zinc transport zrtirt like protein zip famili nicotianamin synthas enzym produc zinc ligand nicotianamin note relat simpl mechan zinc sens regul togeth evolutionari conserv f bzip transcript factor across land plant offer import research opportun one use f bzip regul zinc defici respons tractabl modul evolutionari compar function studi anoth research opportun translat research crop plant modul f bzip activ molecular switch enhanc zinc accumul becom use plant base solut allevi effect zinc defici soil impact crop product crop zinc content consequ human nutrit global	D017360;D029681;D019669	T116;T002
36,348,101	omic base biomark discoveri alzheim diseas alzheim diseas ad common neurodegen disord present patholog hallmark amyloid plaqu tau tangl past year great effort made explor reliabl biomark ad high throughput omic technolog driven multipl level unbias data detect complex etiolog ad provid us new opportun better understand pathophysiolog ad therebi identifi potenti biomark reveal interact network differ molecular level ultim goal multi omic improv diagnosi treatment ad review base current ad patholog current status ad diagnost biomark summar genom transcriptom proteom metabolom conduc discoveri reliabl ad biomark could develop use clinic ad manag	D000544	T047;T048
36,348,083	grey wolf optim algorithm base cauchi gaussian mutat improv search strategi tradit grey wolf optim algorithm gwo receiv widespread attent due featur strong converg perform paramet easi implement howev actual optim project problem slow converg speed easi fall local optim solut paper propos grey wolf optim algorithm base cauchi gaussian mutat improv search strategi cg gwo respons problem cauchi gaussian mutat oper introduc increas popul divers leader wolv improv global search abil algorithm work retain outstand grey wolf individu greedi select mechan ensur converg speed algorithm improv search strategi propos expand optim space algorithm improv converg accuraci experi perform benchmark function cover unimod function multimod function fix dimens multimod function verifi effect algorithm experiment result show compar four classic optim algorithm particl swarm optim algorithm pso whale optim algorithm woa sparrow optim algorithm ssa farmland fertil algorithm ffa cg gwo algorithm show better converg accuraci converg speed global search abil propos algorithm show better perform compar seri improv algorithm improv grey wolf algorithm igwo modifi grey wolf optim algorithm mgwo grey wolf optim algorithm inspir enhanc leadership glf gwo	D000465;D019985	T081;T170
36,348,082	graph generat neural network eeg base epilept seizur detect via discoveri dynam brain function connect dynam complex brain function connect hinder effect use signal process machin learn method diagnos neurolog disord epilepsi paper propos new graph generat neural network ggn model dynam discoveri brain function connect via deep analysi scalp electroencephalogram eeg signal record various region patient scalp brain function connect graph generat extract spatial tempor resolut various onset epilepsi seizur pattern supervis ggn model substanti seizur detect classif experi train ggn model use clinic proven dataset epilept seizur case ggn model achiev accuraci classifi seven type epilept seizur attack outperform accuraci use convolut neural network cnn graph neural network gnn transform model respect present ggn model architectur oper step assist neuroscientist brain specialist use dynam function connect inform detect neurolog disord furthermor suggest merg spatial tempor graph generat design upgrad convent cnn gnn model dynam convolut kernel accuraci enhanc	D012640;D004827	T033;T184;T047;T046
36,348,081	semi supervis learn topograph map analysi time studi bridg segment geograph research use histor map progress consider digit topolog map across year provid valuabl data advanc ai machin learn model provid power analyt tool nevertheless analysi histor map base supervis learn limit labori manual map annot work propos semi supervis learn method transfer annot map across year allow map comparison anthropogen studi across time novel two stage framework first perform style transfer topograph map across year version supervis learn appli synthes map annot investig propos semi supervis train style transfer map annot four wide use deep neural network dnn name u net fulli convolut network fcn deeplabv mobilenetv best perform network u net achiev formula see text formula see text train style transfer synthes map indic propos framework capabl detect target featur bridg histor map without annot comprehens comparison formula see text u net train contrast unpair translat cut generat dataset formula see text achiev compar score formula see text least valid configur mobilenetv train cyclegan synthes dataset also discuss remain challeng futur research direct	D000069553;D016571	T170;T066
36,348,060	use flowcam molecular techniqu assess divers cyanobacteria speci water use food product global occurr cyanobacteria water current remain import subject produc cyanotoxin pose threat human health studi contamin maiz meal mill grind process use cyanobacteria contamin water conduct present studi aim assess divers cyanobacteria sampl process water uncook maiz meal cook maiz meal porridg polymer chain reaction pcr advanc digit flow cytometri flowcam use detect identifi cyanobacteri speci avail sampl primer forward revers tail univers sequenc use amplif sequenc full length rrna gene cyanobacteria found sampl cyanobacteri speci order nostocal pseudanabaenal oscillatorial chroococcal synechococcal unclassifi cyanobacteri order potenti produc cyanotoxin amplifi identifi process water raw maiz meal porridg sampl use pcr imag genus microcysti phormidium leptolyngbya captur process water sampl use flowcam find show presenc cyanobacteria speci process water use maiz meal absenc cook maiz meal presenc cyanobacteria process water like anoth rout human exposur cyanotoxin	D000458;D046931	T007
36,348,055	complic patient bone tumor treat carbon fiber plate intern multicent studi carbon fiber cf plate promis altern metal plate howev report experi orthopaed oncolog remain limit aim studi identifi complic patient bone tumor treat cf plate februari may center retrospect regist patient bone tumor reconstruct use cf plate complic identifi time etiolog complic note similar complic tabul classifi base mechan non mechan paediatr complic mechan complic includ asept loosen graft host non union structur complic non mechan complic includ soft tissu complic infect tumor progress specif paediatr complic includ growth arrest result longitudin angular deform nineti six patient includ median follow time month total patient complic mechan complic includ asept loosen non union structur complic non mechan complic includ soft tissu complic infect tumor progress paediatr complic occur patient studi suggest cf plate safe use demand reconstruct bone tumor resect present seem low complic profil	D001859;D019651	T061;T191

36,348,363

function imag guid carbon ion irradi simultan integr boost local prostat cancer studi protocol phase ii random control clinic trial due physic dose distribut characterist bragg peak biolog effect kind high linear energi transfer ray heavi ion therapi advantag convent photon therapi efficaci safeti base evid prostat cancer lesion treatment common site tumor residu recurr treatment simultan integr boost radiat therapi prostat cancer proven advantag improv efficaci without increas toxic

D011471;D063193;D050397

T061;T191

36,348,362

impact profession midwiv mentor qualiti avail matern care govern sub district hospit bangladesh mix method observ studi studi compar govern sub district hospit bangladesh without global standard midwiv recent introduc midwiv without facil mentor see introduct midwiv associ improv qualiti avail matern care addit analys experi newli deploy midwiv matern staff manag join

D008427;D000071252;D008880

T065;T058;T091;T097

36,348,360

fatal overdos inject human growth hormon case report review literatur human growth hormon hgh categor perform enhanc substanc hgh abus athlet dope purpos

D019382;D004300;D012206;D006973

T121;T116;T125;T047;T046;T052

36,348,359

actual status drug price adjust factor drug price calcul analysi ultra orphan drug develop japan extrem high price facilit drug develop ultra rare diseas ultra orphan drug howev various problem aris term healthcar financ fair status ultra orphan drug price remain ambigu studi investig ultra orphan drug price japan relat drug examin relationship annual expect drug price expect sale expect number patient drug contain new activ ingredi therapeut use list nation health insur drug price list japan april august addit compar price drug price calcul method price calcul adjust factor ultra orphan drug

D016527;D009965

T081;T121;T058

36,348,358

adapt studi protocol evid base make better choic mbc multipl diet activ chang intervent rural appalachian popul rural appalachian resid experi among highest preval chronic diseas prematur mortal decreas life expect nation address grow inequ avoid duplic exist program necessit develop appropri adapt evid base lifestyl intervent yet publish articl explic accomplish contextu cultur adapt

D004032;D017216

T168;T058

36,348,357

apo alzheim diseas pathophysiolog therapeut strategi alzheim diseas ad common caus dementia worldwid preval rapid increas due extend lifespan among increas number genet risk factor identifi apolipoprotein e apo gene remain strongest preval impact half ad case allel apo gene signific increas ad risk allel protect relat common allel gene allel encod three apo protein isoform differ two amino acid posit primari physiolog function apo mediat lipid transport brain peripheri howev addit function apo divers biolog function recogn pathogen apo seed amyloid plaqu brain apo drive earlier abund amyloid apo isoform also differenti effect multipl relat independ pathway complex apo biolog pathobiolog present challeng design effect apo target therapeut strategi review examin key pathobiolog pathway apo relat target strategi specif focus latest technolog advanc tool

D000544

T047;T048

36,348,356

breast cancer subtyp northern thailand barrier satisfactori surviv outcom incid breast cancer bc thailand rise alarm rate annual incid bc thailand doubl span year retrospect studi conduct primari object assess compar surviv rate patient bc stratifi subtyp bc

D001943;D064726

T191

36,348,355

australian podiatrist understand current practic reablement older peopl qualit exploratori studi age australia popul place signific pressur health social age care servic due increas demand provis relat decreas healthcar workforc reablement introduc australian commonwealth govern aim increas older peopl independ age place decreas depend age care servic date research reablement practic focuss intervent physiotherapist occup therapist nurs data avail podiatrist involv aim research explor australian podiatrist understand current practic implement reablement approach older client

D011032;D059825

T091;T097

36,348,354

cortic screw placement spinous process clamp guid cadav studi access accuraci cortic bone trajectori cbt techniqu provid altern method fixat lumbar spine patient osteoporosi accuraci cbt screw placement could improv mechan stabil reduc complic rate

D065289;D013123

T061;T074

36,348,353

collect peripher blood mononucl cell chronic graft versus host diseas immunolog research safeti effect leukapheresi patient chronic graft versus host diseas gvhd major caus late morbid non relaps mortal recipi allogen hematopoiet cell transplant hct biolog howev remain poor understood make studi biolog immunomodulatori therapi difficult task research often hamper lymphopenia common patient preclud studi critic cellular subset across spectrum sever diseas studi explor potenti leukapheresi safe acquir effici store immun cell immunolog research chronic gvhd

D006086;D018380

T061;T047

36,348,352

plan patient specif instrument intraarticular correct osteotomi trapeziometacarp metacarp finger joint intra articular malunion finger lead deform loss function treat intra articular correct osteotomi aim studi evalu radiograph joint congruenc feasibl function outcom three dimension print patient specif instrument psi correct osteotomi trapeziometacarp finger joint

D017759;D050279

T023;T046;T037

36,348,351

caf deriv scube promot malign stem shhgli pathway hepatocellular carcinoma tumour microenviron cirrhot liver excel sourc cancer associ fibroblast caf particip carcinogenesi thus import clarifi crosstalk caf hcc cell relat mechan regul carcinogenesi

D006528;D000072645;D008113

T191;T025

36,348,350

elev spermin remodel immunosuppress microenviron drive modif pd l hepatocellular carcinoma spermin frequent elev tumor tissu bodi fluid cancer patient critic cancer cell prolifer migrat invas howev immun function spermin hepatocellular carcinoma progress remain unknown present studi aim elucid immunosuppress role spermin hepatocellular carcinoma explor under mechan

D006528;D008113

T191

36,348,349

effect qigong exercis physic mental health colleg student systemat review meta analysi physic mental health problem becom serious among colleg student due lifestyl chang increas academ stress qigong exercis regard potenti effect intervent improv physic mental health colleg student

D064906

T061

36,348,348

effect pharmacolog treatment outcom heart failur preserv eject fraction updat systemat review network meta analysi random control trial optim treatment strategi patient heart failur preserv eject fraction hfpef remain uncertain goal studi compar treatment effect differ therapeut agent patient hfpef

D000077203;D006333

T121;T047;T046;T109

36,348,347

interplay pandem season paramet dental emerg servic evalu relationship pandem event dental emerg servic frequent util pattern scope covid pandem analyz consid regard season paramet

D058873;D000086382

T047;T067

36,348,346

conduct support oncolog clinic trial covid pandem challeng strategi coronavirus diseas covid pandem result sever interrupt clinic research worldwid global public health crisi requir investig research rapid develop implement new strategi solut mitig negat impact progress clinic trial paper describ challeng strategi lesson learn regard continu support oncolog clinic trial pandem hope provid insight implement clinic trial public health emerg better prepar futur instancestri registr clinicaltrialsgov servic us nation institut health nct regist januari

D000086382;D009369

T047;T191;T067

36,348,345

vicari trauma hemodialysi healthcar worker besieg ethiopia tigray region call action war ethiopia tigray broke novemb amid arm conflict government institut destroy peopl displac thousand civilian kill region experienc type blockad sinc war broke june time feder govern ethiopia impos sieg cut region rest world due shortag medicin medic suppli wit death otherwis prevent normal condit becom daili predica healthcar worker burden healthcar disintegr particular carri patient chronic medic ill includ patient dialysi

D000068376

T048

36,348,344

autolog micro fragment adipos tissu associ arthroscopi moder sever knee osteoarthr outcom two year follow adipos tissu recent gain grow interest treatment osteoarthr oa aim present studi evalu efficaci singl inject autolog micro fragment adipos tissu amfat associ arthroscopi cartilag debridementmenisc regular select meniscectomymicro drill symptomat knee oa

D020370

T047

36,348,343

exercis train attenu pulmonari inflamm mitochondri dysfunct mous model high fat high carbohydr induc nafld non alcohol fatti liver diseas nafld lead pulmonari dysfunct associ pulmonari inflamm moreov littl known regard therapeut role exercis train pulmonari pathophysiolog nafld present studi aim investig effect exercis train high fat high carbohydr hfhc induc pulmonari dysfunct cbl mice

D065626;D011014

T047;T050

36,348,342

aberr interhemispher function connect major depress disord without anhedonia anhedonia core featur major depress disord mdd subtyp depress mdd anhedonia may except neurobiolog mechan howev neuropatholog anhedonia mdd remain unclear thus studi aim investig brain function differ mdd without anhedonia

D003865

T048

36,348,341

whole genom sequenc analysi reveal circul multipl sar cov variant concern nairobi neighbor counti kenya march juli emerg rapid spread sar cov variant concern voc link new wave covid epidem occur differ region world voc acquir adapt mutat enhanc virus transmiss increas virul reduc respons neutral antibodi kenya experienc six wave covid epidem studi analyz genom sequenc sar cov strain circul nairobi neighbor counti kenya march juli viral rna extract rt pcr confirm covid case follow sequenc use artic network protocol oxford nanopor technolog analysi sequenc data perform use differ bioinformat method analys reveal studi period three sar cov variant concern voc circul nairobi nearbi counti kenya alpha b lineag predomin follow delta b beta b notabl alpha b voc frequent march may delta b domin begin june juli sequenc comparison reveal kenyan virus genet similar circul region although major kenyan virus cluster togeth respect phylogenet lineagesclad signific number interspers among foreign strain march juli studi find indic preval multipl lineag sar cov voc nairobi nearbi counti kenya data suggest recent increas sar cov infect particular nairobi kenya whole attribut introduct communiti transmiss sar cov voc among populac conclus find provid snapshot sar cov variant circul kenya studi period

D000086402;D000086382

T005;T067;T047

36,348,340

evalu novel obes lipid relat indic predictor abnorm glucos toler chines women polycyst ovari syndrom aim evalu perform chines viscer adipos index cvai viscer adipos index vai lipid accumul product lap triglycerid glucos tyg indic screen abnorm glucos toler agt chines women polycyst ovari syndrom pcos use oral glucos toler test ogtt refer test addit essenti compar abil indic bodi mass index bmi waist circumfer wc fast plasma glucos fpg

D011085;D007333;D018149

T047;T046

36,348,339

requir challeng hospit dashboard systemat literatur review today use data administr clinic process quit challeng due larg volum data data collect various sourc lack data structur data manag tool dashboard play import role time visual display critic inform key perform

D006761

T073;T093

36,348,338

risk factor natur menopaus age evid two british popul base birth cohort studi menopaus occur age medic induc refer earli natur menopaus affect around one women serious health consequ consequ includ increas risk caus mortal cardiovascular diseas osteoporosi type diabet

D003924;D008594

T047

36,348,337

hitim hierarch tumor immun microenviron epigenet deconvolut accur cell type resolut tumor microenviron use tumor type specif dna methyl data cellular composit solid tumor microenviron heterogen vari across patient tumor type high resolut profil tumor microenviron cell composit crucial understand biolog clinic implic previous tumor microenviron gene express dna methyl base deconvolut approach shown deconvolv major cell type howev exist method lack accuraci specif tumor type includ limit identif individu cell type

D019175;D009369

T191;T044

36,348,336

development dispar sedentari time period day among us youth cross section studi definit evid show sedentari time st independ risk factor chronic diseas irrespect physic activ despit call limit youth st studi demonstr spike st transit childhood adolesc identifi period day eg school school afterschool even st higher adolesc vs children specifi within daili routin st dispar emerg may import inform intervent strategi period day correspond variat set supervis purpos studi examin devic assess st engag period day development stage nation repres sampl unit state youth

D057185;D061725

T033;T060;T079

36,348,335

oral hygien oral health behavior periodont complaint oral health relat qualiti life pregnant women questionnair base cross section studi aim evalu oral hygien oral health behavior periodont complaint oral health relat qualiti life ohrqol pregnant women southwest saxoni germani

D011788;D009910

T078;T055

36,348,334

comparison magnet reson imag electr imped myographi evalu lumbar skelet muscl composit compar electr imped myographi eim mri assess lumbar skelet muscl composit

D018482;D008161

T023;T029;T024

36,348,333

trend chang factor analysi endometri hyperplasia patient polycyst ovarian syndrom base korean nation health insur databas polycyst ovari syndrom pcos common endocrin disord associ increas risk gynecolog disord endometri hyperplasia eh howev substanti factor comorbid eh pcos remain investig analyz trend chang pcos factor relat comorbid pcos eh use data korea nation health insur knhi claim databas

D011085;D004714;D003924

T047

36,348,332

use video consult support orthoped patient treatment interfac clinic general practition video consult proven power support tool patient doctor interact general covid pandem studi analyz feasibl use orthoped telemed consult otc orthoped patient interfac clinic general practition

D058005;D000086382;D017216

T047;T067;T058;T097

36,348,331

chondromalacia patella increas risk herp zoster popul base studi reactiv herp zoster hz associ diseas stress howev relationship chondromalacia patella cmp hz remain poor understood studi investig relationship cmp risk develop hz

D006562;D002357

T047

36,348,330

fals certainti acquisit anatom physiotherapeut knowledg effici metacognit monitor monitor one thought process specif one state knowledg essenti effect clinic reason know one know compet student health profess need develop student often tend develop fals certainti knowledg longer cours educ time frame requir effect occur remain unclear investig whether student develop fals certainti alreadi one cours unit

D013337;D000067489

T041;T097

36,348,329

polyphenol conyza dioscoridi l amelior alzheim diseas like alter multi target activ two anim model recent investig suggest anticanc agent may inhibit progress alzheim diseas ad patholog conyza dioscoridi l demonstr anticanc antioxid anti inflammatori antidiabet effect studi carri investig efficaci polyphenol conyza dioscoridi l extract pcde ad

D000544;D035401;D019659;D003924

T047;T002;T048

36,348,328

elev serum triglycerid level may key independ predict factor gallbladd cancer risk gallbladd stone diseas patient case control studi gallbladd stone diseas gsd main risk factor gallbladd cancer gbc studi aim reveal bridg metabol syndrom

D007333;D024821;D005706;D015228

T047;T046;T191

36,348,327

lower transmiss sar cov among asymptomat case evid contact trace data oslo norway asymptomat covid case complic surveil track pandem previous studi estim infecte remain asymptomat

D000086402;D000086382

T005;T067;T047

36,348,326

effect ai assist softwar inter intra observ variabl x ray bone age assess preschool children rapid develop deep learn algorithm rapid improv comput hardwar past year ai assist diagnosi softwar bone age achiev good diagnost perform purpos studi investig effect ai assist softwar resid inter observ agreement intra observ reproduc x ray bone age assess preschool children

D012984;D001185

T090;T170;T073;T066

36,348,325

vitamin level among children adolesc adult elder pakistani popul cross section studi vitamin essenti part healthi diet also known sunshin hormon help absorb calcium phosphat within bodi essenti develop teeth bone grow children defici vitamin caus weak bone osteoporosi older individu osteomalacia children also caus loss alveolar bone around teeth increas dental caviti problem associ gum diseas caus depress fatigu appetit loss studi aim observ vitamin defici insuffici suffici among children adult adolesc elder pakistani popul

D014807;D014808

T121;T047;T127

36,348,324

perceiv barrier toward import applic medic research sourc gender dispar among medic undergradu littl known gender dispar among medic undergradu develop world therefor studi aim explor attitud perceiv barrier among jordanian medic student particular women

D013337;D035843

T062;T097

36,348,323

second opinion opportun declin patient typolog experi regard decis make process preced elect surgeri germani address problem overus elect surgeri support patient decis make process second opinion direct introduc germani enabl patient statutori health insur obtain second opinion certain surgic indic studi aim identifi base experi patient undergon elect surgeri role seek second opinion reach decis

D003657;D017558

T061;T041

36,348,322

genom wide identif analysi bzip gene famili reveal role develop drought stress wheel wingnut cyclocarya paliurus bzip gene famili import role various biolog process includ develop stress respons howev littl inform gene famili avail wheel wingnut cyclocarya paliurus result studi identifi bzip gene c paliurus genom analyz phylogenet relationship chromosom locat gene structur collinear gene express profil bzip gene could divid group uneven distribut among c paliurus chromosom analysi cis regulatori element indic bzip promot associ phytohormon stress respons express pattern bzip gene leav differ among development stage addit sever bzip member differenti express drought stress express pattern verifi rt qpcr

D055864;D018506

T045;T070

36,348,321

molecular character phylogenet analysi porcin epidem diarrhea virus strain circul china porcin epidem diarrhea virus pedv enter coronavirus becom major causat agent acut gastroenter piglet sinc china

D053485;D013553;D018352

T005;T047

36,348,320

teach card low cost brief materi teach basic life support year old primari school children quasi experiment combin design studi teach basic life support bls school key initi improv surviv rate hospit cardiac arrest low cost train materi reach wider popul aim compar effect use teach card tradit instructor led combin method bls skill attitud evalu long term effect two month

D016887

T061

36,348,318

rapid precis identif bloodstream infect use pre treatment protocol combin high throughput multiplex genet detect system bloodstream infect bsi life threaten condit high morbid mortal rate worldwid earli diagnosi bsi critic avoid unnecessari applic antimicrobi agent proper treatment howev current standard method base blood cultur time consum thus fail provid time etiolog diagnosi bsi common pcr base detect might inhibit matrix compon

D016470;D018805;D003141

T047;T046

36,348,317

differenti properti kras transvers transit mutat non small cell lung cancer associ environment factor clinic outcom kras mutat non small cell lung cancer nsclc account nsclcs white patient east asian respect therefor regard major therapeut target howev epidemiolog clinic characterist fulli elucid wide varieti mutat subtyp focus two distinct base substitut type transvers mutat transit mutat well associ environment factor clinic outcom

D002289;D008175

T191

36,348,316

lost explan intern conflict discours adhd psychoeduc psychiatr classif understood mani differ way children adhd parent psychoeduc import sourc inform shape understand moreov psychoeduc often taken children parent repres stori understood therapist result way psychoeduc formul may affect therapeut allianc one robust mediat treatment outcom addit psychoeduc may indirect influenc way understand psycholog differ societi

D001289

T048

36,348,315

bodi mass index incid lung cancer hunt studi use observ mendelian random approach tradit observ studi shown invers associ bodi mass index bmi lung cancer risk mendelian random mr analysi use genet variant instrument bmi may clarifi natur associ

D008175;D000230;D000077192

T191

36,348,314

technolog free predictor preterm birth singleton women threaten preterm labor prospect cohort studi predict preterm birth still challeng due multipl etiolog prospect cohort studi aim determin technolog free predictor preterm birth singleton women threaten preterm labor

D047928;D007752

T046

36,348,313

effect behavior therapi base counsel anxious mother infant colic random control clinic trial given possibl effect matern anxieti sever colic pain infant studi aim investig effect behavior therapi counsel infantil colic primari outcom matern anxieti mother infant attach secondari outcom anxious mother colicki infant

D003085

T033;T184

36,348,312

enterovirus detect differ region madagascar reveal higher abund enterovirus speci c area sever outbreak vaccin deriv poliovirus occur poliomyel outbreak due pathogen vaccin deriv poliovirus vdpvs threaten complic global polio erad initi vdpvs genet recombin non polio enterovirus npev speci c littl known factor favor genet macroevolut process sinc madagascar experienc sever outbreak poliomyel due vdpvs vdpvs isol south island current studi explor viral factor promot explain emerg recombin vdpvs madagascar

D017955;D004770;D004769;D011051;D030015;D023321

T129;T121;T109;T005;T047

36,348,311

patient ectop acth syndrom might better prognosi bronchopulmonari carcinoid lymph node metastasi receiv radic surgeri singl centr retrospect studi last year china bronchopulmonari carcinoid bpcs rare malign known one common caus ectop adrenocorticotrop hormon acth syndrom surgeri mainstay therapi one key question consid surgic treatment impact local lymph node metastas sought determin risk factor prognosi ln metastas resect carcinoid patient

D000182;D002276

T047;T191

36,348,310

design feasibl implement strategi address chaga guidelin engag focus attend women childbear age children primari healthcar level argentina pilot studi chaga public health problem especi latin america exacerb migratori movement increas urban argentina among countri highest estim preval region peopl infect mother child main mode transmiss vertic transmiss signific reduc treat women childbear age sever guidelin region recommend treatment primari prevent strategi child secondari prevent strategi women famili despit recommend women childbear age alway treat children receiv time diagnosi treatment object research design implement strategi improv use chaga guidelin focus attend women childbear age children primari healthcar level pilot three primari health care center argentina

D058873;D000086382

T047;T067

36,348,309

comparison supervis exercis therapi without biopsychosoci approach chronic nonspecif low back pain random control trial biopsychosoci rehabilit recommend chronic nonspecif low back pain cnlbp howev effect compar tradit supervis exercis therapi cnlbp treatment still unclear

D017116;D059350

T184;T047

36,348,308

two case infantil onset primari general glucocorticoid hypersensit effect mifepriston primari general glucocorticoid hypersensit pggh rare diseas caus termin organ hypersensit glucocorticoid aetiolog unknown incid pggh extrem rare especi children date literatur etiolog prognosi treatment pggh scarc aim studi describ case two chines children infantil onset pggh one famili one die one treat mifepriston two youngest children pggh report literatur

D003480;D006967

T047;T046

36,348,307

effect evalu kangaroo mother care lipe area guizhou provinc china kangaroo mother care kmc refer mother babi birth earli start continu skin contact way newborn care simpl oper easi control low cost larg high consumpt equipmentso suitabl develop area medic resourc relat scarc guizhou provinc relat poor provinc china mani ethnic minor

D060127

T061

36,348,306

fat storag induc transmembran protein beyond mediat lipid droplet format fat storag induc transmembran protein fitm initi identifi member conserv endoplasm reticulum er resid transmembran protein gene famili found involv lipid droplet ld format recent sever studi demonstr abil fitm direct bind triglycerid diacylglycerol diphosphatas activ hydrolyz fatti acyl coa might enabl fitm maintain format lipid droplet engag lipid metabol protect cellular stress base distribut fitm tissu import role lipid droplet biolog lipid metabol discov fitm close relat muscl develop adipocyt differenti energi metabol accord abnorm express fitm associ type diabet lipodystrophi also cardiac diseas sever type cancer studi review structur distribut express regul function fitm potenti relationship various metabol diseas hope provid inspir fruit research direct applic fitm protein moreov review provid import theoret basi applic fitm diagnosi treatment relat diseas

D066292;D003924

T026;T047

36,348,305

mir p suppressor colorect cancer earli stage promot colorect cancer metastasi late stage regul akt signal evok emt mediat anoiki mir p general consid tumor suppressor earli stage colorect cancer regul occur progress later stage associ metastasi indic mir p may play dual role colorect cancer crc explor detail mechan mir p carcinogen import

D035683;D015179

T123;T191;T114

36,348,304

effect pregnanc discrimin postpartum depress symptom follow studi pregnanc discrimin workplac preval worldwid howev studi examin effect pregnanc discrimin mother perinat mental health aim investig associ pregnanc discrimin postpartum depress symptom mediat effect prenat depress symptom associ

D019052

T048

36,348,303

carpal tunnel syndrom secondari tumor calcinosi case report review literatur carpal tunnel syndrom cts preval peripher nerv entrap diseas pathophysiolog multifactori defin idiopath case present rare case cts secondari tumor calcinosi search english literatur present detail publish case entiti

D002349;D002114

T047;T046

36,348,301

interpret dic risk predict model base convolut neural network time seri data dissemin intravascular coagul dic complex life threaten syndrom associ end stage differ coagul disord earli predict risk dic develop urgent clinic need reduc advers outcom howev effect approach model identifi earli dic still lack studi novel interpret deep learn base time seri use predict risk dic studi cohort includ icu patient bed academ hospit januari januari experiment result show model achiev excel perform auc accuraci f gradient weight class activ map grad cam use explain predict model identifi patient dic decis basi model display form heat map model use identifi high risk patient dic earli help earli intervent dic patient improv treatment effect

D004211

T047

36,348,300

public knowledg dementia risk reduct norway sever modifi lifestyl risk factor dementia identifi unclear much norwegian public know relationship lifestyl brain health therefor studi aim investig knowledg modifi dementia risk protect factor belief attitud toward dementia dementia risk reduct random select subsampl norwegian popul

D003704;D003920

T047;T048

36,348,299

autom classif protein express level immunohistochemistri imag improv detect cancer biomark express chang protein associ cancer progress use biomark cancer diagnosi autom system frequent appli larg scale detect protein biomark provid valuabl complement wet laboratori experi exampl previous work use immunohistochem imag base machin learn classifi protein subcellular locat screen biomark protein chang locat colon cancer tissu tool could recogn locat biomark consid effect protein express level chang screen process

D014408;D009369

T123;T191

36,348,298

investig public awar prevail attitud percept toward domest violenc abus unit kingdom qualit studi report case domest violenc abus dva increas sinc advent covid pandem ensu lockdown understand general public view dva vital would help develop target intervent effect public polici tackl rise problem societi qualit studi investig public awar attitud percept toward dva explor mechan tackl dva communiti set uk

D000086382;D017579

T054;T047;T067;T048

36,348,297

pathogenesi plant associ pseudomona aeruginosa caenorhabd elegan model pseudomona aeruginosa global dread pathogen trigger fatal immuno compromis individu agricultur ecosystem massiv reservoir bacterium sever studi recommend p aeruginosa promot plant growth howev limit attempt evalu health risk associ plant associ p aeruginosa current studi hypothes agricultur p aeruginosa strain exhibit eukaryot pathogen despit plant benefici trait

D011550;D011552

T047;T007

36,348,296

preval sleep relat problem risk communiti dwell older adult popul cross section survey base studi despit evid advers health consequ inadequ restor sleep older adult assess sleep quantiti qualiti use sleep aid routin done aim character sleep problem sleep risk advic receiv sleep communiti dwell older adult popul overal subgroup health condit function difficulti

D007319;D000163;D012893;D020181

T184;T047;T048

36,348,295

descript comparison postop function patient hip fractur rebro univers hospit compar cross section studi hip fractur global problem probabl increas hip fractur impair health aspect creat demand postop care studi describ compar patient hip fractur increas knowledg group could basi optim aftercar dimens rehabilit

D018737;D006620

T081;T040;T037

36,348,294

serum marker ct characterist coronari calcifi nodul assess intravascular ultrasound calcifi nodul cn type potenti vulner plaqu format mechan remain unknown studi assess serum marker comput tomographi angiographi cta characterist cn valid intravascular ultrasound ivus

D058226;D003324;D002114

T047;T046;T020;T031

36,348,293

distribut induc characteris prophag latilactobacillus sakei lactic acid bacteria lab use starter wide varieti food ferment number report phage infect lab steadili increas year inform phage associ latilactobacillus sakei frequent use meat starter remain scarc

D039002;D001435

T005

36,348,292

low dose nivolumab advanc hepatocellular carcinoma approv dose nivolumab mgkg flat dose mg indic dose respons relationship nivolumab therefor low dose regimen may option reduc financi toxic studi design investig efficaci safeti low dose nivolumab manag hepatocellular carcinoma hcc

D006528;D008113;D006526

T047;T191

36,348,290

function mri radiom base assess pelvic bone marrow chang concurr chemoradiotherapi cervic cancer quantifi dose respons relationship chang pelvic bone marrow pbm function mr radiom featur rf concurr chemoradiotherapi ccrt patient cervic cancer establish correl hematolog toxic provid basi pbm spare

D002583;D050397

T061;T191

36,348,289

develop verif nomogram predict prognosi resect gastric cancer outlet obstruct prognosi patient gastric cancer gc gastric outlet obstruct goo gastrectomi high variabl studi aim develop nomogram predict prognosi patient

D013274;D017219

T047;T191

36,348,288

x box bind protein key modul heal endotheli cell novel ec phenotyp promot angiogenesi mcao endotheli cell ec play import role angiogenesi vascular reconstruct pathophysiolog ischem stroke previous investig provid profound cerebr vascular atlas physiolog condit fail identifi new diseas relat cell subtyp aim identifi new ec subtyp determin key modul gene

D042783;D020244

T047;T020;T025

36,348,287

reproduc repeat semi autom pipelin quantifi trapeziometacarp joint angl use dynam comput tomographi trapeziometacarp tmc joint mechan complex joint common affect musculoskelet diseas osteoarthr quantifi vivo tmc joint biomechan joint angl tradit reflect marker base method difficult due joint locat hand dynam comput tomographi ct facilit quantif tmc joint motion continu captur three dimension volum time howev post process dynam ct dataset time intens autom method need reduc process time allow applic larger clinic studi purpos work introduc fast semi autom pipelin quantifi joint angl dynam ct scan tmc joint evalu associ error joint angl translat comput mean reproduc repeat studi

D013933;D014057

T060;T023

36,348,286

effect increas lp follow statin therapi cardiovascular prognosi secondari prevent popul coronari arteri diseas lipoprotein lp independ risk factor coronari arteri diseas cad recent studi indic statin tend increas lp level howev associ statin mediat increas lp level cad determin method studi includ patient acut coronari syndrom ac underw percutan coronari intervent pci lp level measur baselin month statin therapi studi endpoint major advers cardiovascular event mace hazard ratio mace adjust potenti confound use cox regress

D003324;D019161;D062645

T061;T121;T047;T109

36,348,284

short form develop specif modul qlicd crf v assess qualiti life patient chronic renal failur short instrument would enhanc viabil studi therefor aim shorten specif modul spd qualiti life instrument chronic diseas chronic renal failur qlicd crf assess qualiti life patient chronic renal failur

D011788;D007676

T078;T047

36,348,283

correl galectin rdw hepc hs ferritin prognosi patient acut onset chronic heart failur chronic heart failur chf character high hospit rate high mortal rate particular import identifi biomark predict prognosi patient acut attack chf

D037502;D006333

T129;T047;T046;T116

36,348,282

diabet retinopathi corneal endotheli paramet analyt cross section studi investig possibl associ differ pattern diabet retinopathi dr corneal endothelium cell type diabet mellitus patient

D003930;D003924

T047

36,348,281

collect encod protein properti enrich protein languag model pre train natur languag process model larg natur languag corpus natur transfer learn knowledg protein domain fine tune specif domain task howev studi focus enrich protein languag model joint learn protein properti strong correl protein task elabor design multi task learn mtl architectur aim deciph implicit structur evolutionari inform three sequenc level classif task protein famili superfamili fold consid co exist contextu relev human word protein languag employ bert pre train larg natur languag corpus backbon handl protein sequenc import encod knowledg obtain mtl stage well transfer fine grain downstream task tape experi structur evolut relat applic demonstr approach outperform mani state art transform base protein model especi remot homolog detect

D009323;D011506

T123;T116;T066

36,348,280

cranium quasi experiment studi improv metabol screen hiv test communiti mental health clinic compar usual care individu serious mental ill often receiv guidelin concord metabol screen human immunodefici virus hiv test contribut increas morbid prematur mortal studi evalu effect cranium cardiometabol risk assess treatment novel integr model underserv popul mental ill intervent increas metabol screen hiv test among patient serious mental ill communiti mental health clinic compar usual care

D008603;D015658

T047;T041

36,348,279

phylogenet analysi stress respons plant u small nuclear ribonucleoprotein b gene famili altern splice import channel gene express regul protein diversif addit major reason consider differ number gene protein eukaryot plant u small nuclear ribonucleoprotein b ub compon splice complex u snrnp play import role current studi investig plant ub mechan remain unclear

D017413;D017381

T026;T123;T116

36,348,278

stereotact bodi radiat therapi effect local treatment advanc hepatocellular carcinoma patient inferior vena cava right atrial tumor thrombus aim studi evalu curat effect safeti stereotact bodi radiat therapi sbrt treat hepatocellular carcinoma hcc patient inferior vena cava ivctt right atrial tumor thrombus ratt

D006528;D016634;D008113;D013927

T061;T191;T046

36,348,277

phylogenom analysi develop molecular marker determin twelv plum cultivar prunus rosacea plum one import econom crop rosacea famili produc world china mani local varieti genom inform limit genet studi first sequenc assembl analyz plastom twelv plum cultivar develop molecular marker distinguish

D000068242;D027861;D027824

T168;T002

36,348,276

pyridostigmin reduc mortal patient sever sar cov infect phase random control trial respiratori failur sever coronavirus diseas covid associ sever inflammatori respons acetylcholin ach reduc system inflamm experiment bacteri viral infect pyridostigmin increas half life endogen ach potenti reduc system inflamm aim determin pyridostigmin decreas composit outcom invas mechan ventil imv death adult patient sever covid

D000086382

T047;T067

36,348,275

associ live arrang cognit declin older adult nation repres longitudin studi china live arrang critic surviv well older peopl especi china filial pieti cultur demand adult children care serv parent studi aim explor associ live arrang cognit declin among older peopl china

D012111;D060825

T078;T082;T083;T033;T056;T096;T081;T048

36,348,274

fadd key molecular player cancer progress cancer lead diseas relat caus death worldwid despit advanc therapeut intervent cancer remain major global public health problem cancer pathogenesi extrem intric larg unknown fas associ protein death domain fadd initi identifi adaptor protein death receptor mediat extrins apoptosi recent evid suggest fadd play vital role non apoptot cellular process prolifer autophagi necroptosi fadd express activ modul complic network process dna methyl non code rna post translat modif fadd dysregul shown close associ pathogenesi numer type cancer howev detail mechan fadd dysregul involv cancer progress still fulli understood review main summar recent find structur function regulatori mechan fadd focus role cancer progress clinic implic fadd biomark therapeut target cancer patient also discuss inform review herein may expand research understand fadd contribut develop fadd base therapeut strategi cancer patient

D017209;D009369

T123;T191;T116;T043

36,348,273

associ chang depress symptom hip fractur among middl age older chines individu prospect cohort studi although studi shown depress symptom associ increas risk hip fractur hf depress symptom dynam unclear whether hf risk persist depress symptom remit studi aim examin associ chang depress symptom hf risk

D003863;D012179

T033;T184;T048

36,348,272

breeder prevent pathogen adapt select increas resist infecti diseas recent research show genet select high potenti reduc preval infecti diseas livestock howev like intervent target infecti diseas genet select livestock exert select pressur pathogen popul select pathogen may lead escap strategi reduc effect select livestock diseas resist thus success breed livestock lower diseas preval essenti develop strategi prevent invas pathogen mutant escap host resist investig condit escap mutant replac wild type pathogen close livestock popul use mathemat model diseas transmiss

D058751;D003141

T047;T008

36,348,271

multipl instanc neural network base spars attent cancer detect use cell receptor sequenc earli detect cancer much explor due paramount import biomed field among differ type data use answer biolog question studi base cell receptor tcrs recent spotlight due grow appreci role host immun system tumor biolog howev one mani correspond patient multipl tcr sequenc hinder research simpli adopt classic statisticalmachin learn method recent attempt model type data context multipl instanc learn mil despit novel applic mil cancer detect use tcr sequenc demonstr adequ perform sever tumor type still room improv especi certain cancer type furthermor explain neural network model fulli investig applic articl propos multipl instanc neural network base spars attent minn sa enhanc perform cancer detect explain spars attent structur drop uninform instanc bag achiev interpret better predict perform combin skip connect experi show minn sa yield highest area roc curv score averag measur across differ type cancer compar exist mil approach moreov observ estim attent minn sa identifi tcrs specif tumor antigen cell repertoir

D016571;D009369

T170;T191

36,348,269

bone marrow mesenchym stem cell deriv exosom shuttl mir p allevi mechan allodynia rat target notch microglia studi probe function mechan bone marrow mesenchym stem cell bmsc deriv exosom load mir p mechan allodynia

D055354;D035683;D059630

T026;T123;T025;T114

36,348,268

discuss caus thrombolysi failur patient stemi case report spontan coronari arteri dissect scad emerg increas diagnos caus st segment elev myocardi infarct stemi easili miss delay effect use coronari angiographi cag advanc intracoronari imag examin stemi patient led increas detect scad

D000072657;D000086382;D009203

T047;T067

36,348,267

cna correl consensus base cross taxonomi network analysi composit microbi data studi co occurr network structur microbi sampl one critic approach understand perplex delic relationship microb host diseas also critic develop tool investig co occurr network differenti abund analys reveal diseas relat taxa taxa relationship addit also necessari tighten co occurr network smaller modul increas abil function annot interpret taxa taxa relationship also critic retain phylogenet relationship among taxa identifi differenti abund pattern use resolv contradict function report differ studi

D010802

T062;T078

36,348,266

attenu virul resist superbug staphylococcus aureus bacteria isol neonat sepsi ascorb acid dexamethason sodium bicarbon infect affect neonat caus staphylococcus aureus widespread healthcar facil henc novel strategi need fight pathogen studi aim investig effect fda approv medic ascorb acid dexamethason sodium bicarbon reduc virul resist staphylococcus aureus bacteria caus neonat sepsi seek suitabl altern problem multi drug resist

D055624;D000071074;D013203

T047;T007

36,348,202

predat capac bradymonabacteria recent discov group order bradymonadal isol marin sediment bacteri predat vital feed behavior affect communiti structur maintain biodivers howev predatori bacteri speci coastal sediment compar poor describ studi predat capac nine cultur bradymonabacteria strain belong recent discov order bradymonadal determin differ type prey predatori effici bradymonabacteria increas initi prey proport mix cultur decreas initi prey proport number surviv prey bacteri cell signific decreas h predat bradymonabacteria strain tmq seh b fa howev growth prey strain occur presenc bradymonabacteria strain tmq tmq tmq v yn initi prey proport decreas bradymonabacteria strain prey effici furthermor establish neighbor coloni prey destroy bradymonabacteria invad predat capac determin predat abil strain motil agar surfac find provid new insight potenti ecolog signific predatori bradymonabacteria may serv potenti probiot use aquacultur

D011235;D020564

T007;T054

36,348,172

f bzip regul zn defici respons land plant review describ zinc sens transcript regul zinc defici respons arabidopsi discuss evolutionari conserv land plant facilit translat approach improv zn nutrit valu crop speci zinc essenti micronutri live organ due presenc larg number protein structur catalyt cofactor plant zinc homeostasi mechan compris uptak soil transport distribut throughout plant provid adequ cellular zinc avail discuss transcript regul respons zinc defici zinc sens mechan arabidopsi evolutionari conserv land plant arabidopsi f group basic region leucin zipper f bzip transcript factor bzip bzip function simultan sensor intracellular zinc status direct bind zinc ion central regul zinc defici respons target gene includ zinc transport zrtirt like protein zip famili nicotianamin synthas enzym produc zinc ligand nicotianamin note relat simpl mechan zinc sens regul togeth evolutionari conserv f bzip transcript factor across land plant offer import research opportun one use f bzip regul zinc defici respons tractabl modul evolutionari compar function studi anoth research opportun translat research crop plant modul f bzip activ molecular switch enhanc zinc accumul becom use plant base solut allevi effect zinc defici soil impact crop product crop zinc content consequ human nutrit global

D017360;D029681;D019669

T116;T002

36,348,101

omic base biomark discoveri alzheim diseas alzheim diseas ad common neurodegen disord present patholog hallmark amyloid plaqu tau tangl past year great effort made explor reliabl biomark ad high throughput omic technolog driven multipl level unbias data detect complex etiolog ad provid us new opportun better understand pathophysiolog ad therebi identifi potenti biomark reveal interact network differ molecular level ultim goal multi omic improv diagnosi treatment ad review base current ad patholog current status ad diagnost biomark summar genom transcriptom proteom metabolom conduc discoveri reliabl ad biomark could develop use clinic ad manag

D000544

T047;T048

36,348,083

grey wolf optim algorithm base cauchi gaussian mutat improv search strategi tradit grey wolf optim algorithm gwo receiv widespread attent due featur strong converg perform paramet easi implement howev actual optim project problem slow converg speed easi fall local optim solut paper propos grey wolf optim algorithm base cauchi gaussian mutat improv search strategi cg gwo respons problem cauchi gaussian mutat oper introduc increas popul divers leader wolv improv global search abil algorithm work retain outstand grey wolf individu greedi select mechan ensur converg speed algorithm improv search strategi propos expand optim space algorithm improv converg accuraci experi perform benchmark function cover unimod function multimod function fix dimens multimod function verifi effect algorithm experiment result show compar four classic optim algorithm particl swarm optim algorithm pso whale optim algorithm woa sparrow optim algorithm ssa farmland fertil algorithm ffa cg gwo algorithm show better converg accuraci converg speed global search abil propos algorithm show better perform compar seri improv algorithm improv grey wolf algorithm igwo modifi grey wolf optim algorithm mgwo grey wolf optim algorithm inspir enhanc leadership glf gwo

D000465;D019985

T081;T170

36,348,082

graph generat neural network eeg base epilept seizur detect via discoveri dynam brain function connect dynam complex brain function connect hinder effect use signal process machin learn method diagnos neurolog disord epilepsi paper propos new graph generat neural network ggn model dynam discoveri brain function connect via deep analysi scalp electroencephalogram eeg signal record various region patient scalp brain function connect graph generat extract spatial tempor resolut various onset epilepsi seizur pattern supervis ggn model substanti seizur detect classif experi train ggn model use clinic proven dataset epilept seizur case ggn model achiev accuraci classifi seven type epilept seizur attack outperform accuraci use convolut neural network cnn graph neural network gnn transform model respect present ggn model architectur oper step assist neuroscientist brain specialist use dynam function connect inform detect neurolog disord furthermor suggest merg spatial tempor graph generat design upgrad convent cnn gnn model dynam convolut kernel accuraci enhanc

D012640;D004827

T033;T184;T047;T046

36,348,081

semi supervis learn topograph map analysi time studi bridg segment geograph research use histor map progress consider digit topolog map across year provid valuabl data advanc ai machin learn model provid power analyt tool nevertheless analysi histor map base supervis learn limit labori manual map annot work propos semi supervis learn method transfer annot map across year allow map comparison anthropogen studi across time novel two stage framework first perform style transfer topograph map across year version supervis learn appli synthes map annot investig propos semi supervis train style transfer map annot four wide use deep neural network dnn name u net fulli convolut network fcn deeplabv mobilenetv best perform network u net achiev formula see text formula see text train style transfer synthes map indic propos framework capabl detect target featur bridg histor map without annot comprehens comparison formula see text u net train contrast unpair translat cut generat dataset formula see text achiev compar score formula see text least valid configur mobilenetv train cyclegan synthes dataset also discuss remain challeng futur research direct

D000069553;D016571

T170;T066

36,348,060

use flowcam molecular techniqu assess divers cyanobacteria speci water use food product global occurr cyanobacteria water current remain import subject produc cyanotoxin pose threat human health studi contamin maiz meal mill grind process use cyanobacteria contamin water conduct present studi aim assess divers cyanobacteria sampl process water uncook maiz meal cook maiz meal porridg polymer chain reaction pcr advanc digit flow cytometri flowcam use detect identifi cyanobacteri speci avail sampl primer forward revers tail univers sequenc use amplif sequenc full length rrna gene cyanobacteria found sampl cyanobacteri speci order nostocal pseudanabaenal oscillatorial chroococcal synechococcal unclassifi cyanobacteri order potenti produc cyanotoxin amplifi identifi process water raw maiz meal porridg sampl use pcr imag genus microcysti phormidium leptolyngbya captur process water sampl use flowcam find show presenc cyanobacteria speci process water use maiz meal absenc cook maiz meal presenc cyanobacteria process water like anoth rout human exposur cyanotoxin

D000458;D046931

T007

36,348,055

complic patient bone tumor treat carbon fiber plate intern multicent studi carbon fiber cf plate promis altern metal plate howev report experi orthopaed oncolog remain limit aim studi identifi complic patient bone tumor treat cf plate februari may center retrospect regist patient bone tumor reconstruct use cf plate complic identifi time etiolog complic note similar complic tabul classifi base mechan non mechan paediatr complic mechan complic includ asept loosen graft host non union structur complic non mechan complic includ soft tissu complic infect tumor progress specif paediatr complic includ growth arrest result longitudin angular deform nineti six patient includ median follow time month total patient complic mechan complic includ asept loosen non union structur complic non mechan complic includ soft tissu complic infect tumor progress paediatr complic occur patient studi suggest cf plate safe use demand reconstruct bone tumor resect present seem low complic profil

D001859;D019651

T061;T191