PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
|---|---|---|---|
34,662,480 | spatial host relat genom variat partial sympatr cactophag moth speci survey pattern genet variat natur sympatr allopatr popul recent diverg speci necessari understand process drive intra interspecif diversif south american moth cactoblasti cactorum cactoblasti doddi cactoblasti bucyrus special use cacti host plant speci partial differ geograph rang differ pattern host plant use howev area overlap particular northwestern argentina sympatr use combin genom wide snps mitochondri data assess intra interspecif genet variat investig relat role geographi host plant genet diverg also search genet footprint hybrid speci identifi three well delimit speci detect sign hybrid area sympatri result support hypothet scenario allopatr speciat generalist c cactorum genet interchang secondari geograph contact pair specialist c bucyrus c doddi probabl speciat sympatr case adapt new host plant probabl play import role speciat result also suggest interplay geographi host plant use driver diverg limit gene flow intra interspecif level | D009036;D061350 | T070;T204;T098 |
34,662,479 | defenc duplic relat phenotyp glyphos resist epsp gene copi number variat amaranthus palmeri gene copi number variat cnv increas associ organism respons environment stress know littl quantit relat cnv phenotyp variat studi quantifi relat variat epsp enolpyruvylshikim phosphat synthas copi number use digit drop pcr variat phenotyp glyphos resist popul amaranthus palmeri palmer amaranth rang expand agricultur weed overal detect signific posit relat popul mean copi number resist major popul exhibit high glyphos resist yet maintain low resist individu result bimod mani popul also investig threshold model relat copi number resist found evid threshold epsp copi steep increas resist threshold follow much shallow increas across individu copi number increas rang variat resist decreas yield increas frequenc high phenotyp resist individu among popul detect declin variat sd mean phenotyp resist increas moder high consist predict phenotyp resist increas popul stabil select decreas variat trait studi demonstr popul palmeri harbour wide variat epsp copi number phenotyp glyphos resist reflect histori templat futur resist evolut | D027721;D006540 | T131;T002 |
34,662,478 | evolut seed mass associ mate system multipl plant famili flower plant evolut self fertil self oblig outcross regard one preval evolutionari transit evolut self often accompani various chang genom physiolog morpholog properti particular set reproduct trait observ typic self speci call self syndrom mathemat model base kinship theori genet imprint predict seed mass becom smaller self speci compar outcross congen consequ reduc conflict matern patern deriv allel self plant test predict examin associ mate system seed mass across wide rang taxa speci consid potenti confound factor phylogenet relationship growth form focus three plant famili solanacea brassicacea asteracea inform mate system abund analysi perform famili separ phylogenet relationship control consist observ selfer repres self compat speci tend smaller seed mass compar outcross repres self incompat speci famili summari analysi suggest small seed also consid hallmark self syndrom although note mate system relat small effect seed mass variat | D019607;D057945 | T040;T002 |
34,662,477 | associ periop pupillari paramet postop acut pain pilot cross section studi aim explor capac periop pupillari variabl predict acut pain post anesthesia care unit pacu | D059787;D011680 | T023;T184 |
34,662,476 | character identif novel microbi consortium effect ferment qualiti enzymat hydrolysi steril rice straw isol enrich lignocellulolyt microbi consortia yak bos grunnien rumen evalu effect ferment characterist enzymat hydrolysi rice straw silag | D059013;D012275 | T168;T002;T001 |
34,662,474 | short chain fatti acid pregnanc multipl sclerosi prospect cohort studi short chain fatti acid scfas pro anti inflammatori properti relationship multipl sclerosi ms relaps pregnanc remain unknown studi aim explor scfa profil ms patient pregnanc assess associ appear relaps pregnanc postpartum | D009103 | T047 |
34,662,472 | prepar campomanesia reitziana reduc gastrointestin motil castor oil induc diarrhea non opioid non dopaminerg pathway mice display antimicrobi activ vitro studi investig antidiarrh potenti aqueous extract aecr hydroalcohol extract campomanesia reitziana leav hecr ethyl acet eaf dichloromethan fraction dcmf myricitrin isol eaf | D000890;D002368 | T121;T109 |
34,662,471 | cardiovers recent onset atrial fibril use intraven antiarrhythm european perspect pharmacolog cardiovers use intraven antiarrhythm agent common indic symptomat patient recent onset atrial fibril af except hemodynam unstabl patient requir emerg direct current electr cardiovers major hemodynam stabl patient pharmacolog cardiovers repres valid option requir clinician familiar properti use antiarrhythm agent main characterist select intraven antiarrhythm agent convers recent onset af report success rate possibl advers event discuss among intraven antiarrhythm flecainid propafenon amiodaron sotalol dofetilid ibutilid vernakal common use antazolin old antihistamin agent antiarrhythm properti also report give encourag result poland intraven flecainid propafenon class agent still recommend recent guidelin intraven new class iii agent dofetilid ibutilid high rapid efficaci convert af sinus rhythm requir strict surveil electrocardiogram ecg monitor intraven administr potenti risk qt prolong torsad de point prevent proper manag vernakal partial atrial select shown high success rate safe real life use | D000638;D001281 | T047;T121;T109;T046 |
34,662,468 | magnet reson imag valid medial transthyroid ultrasound guid stellat ganglion block pilot studi ultrasound guid stellat ganglion block ussgb facilit improv accuraci needl posit applic lesser volum local anesthet la approach ussgb howev fulli optim respect efficaci technic conveni pilot studi examin anatom posit spatial distribut small volum la inject dispens medial transthyroid ussgb via magnet reson imag mri assess effect cervic sympathet nerv | D001340;D013233 | T023;T061 |
34,662,467 | strong interfac via weak interact ultratough malleabl polylact acidpolyhydroxybutyr biocomposit bio base biodegrad polym composit notabl poli l lactic acid plla poli hydroxybutyr phb repres promis solut replac convent petroleum base plastic howev brittl low miscibl plla phb remain two major obstacl practic applic work first pllaphb blend report melt mix rigid compon poli methyl methacryl pmma driven favor entropi pmma form interfaci nanolay transform morpholog result blend ternari blend show fold increas elong fold tough metal like malleabl bend twist retain high stiff gpa strength mpa mechan improv aris numer craze fibril shear deform matrix induc incorpor pmma furthermor generic strategi appli design mechan robust biocomposit advanc green devic | D011091;D011108 | T104;T122;T109 |
34,662,465 | long term durabl percev aortic valv implant insid calcifi homograft root patient klippel trenaunay weber syndrom percev valv sutureless surgic bioprosthes design aortic posit report use percev sutureless valv redo aortic valv replac insid heavili calcifi homograft root patient klippel trenaunay weber syndrom | D001024;D001705;D006350;D019918;D007715;D000071062 | T074;T047;T061 |
34,662,464 | function cd human annulus fibrosus cell mechan regul tgf mous outer annulus fibrosus af previous shown contain cd af cell vitro cultur exposur transform growth factor beta tgf increas express cd howev neither specif function cd under mechan tgf upregul cd af cell elucid yet current studi cd express role cultur human af cell investig studi cell capac matrix contract gene express function af marker addit tgf pathway block sever pathway inhibitor short hairpin rnas shrnas target smad non smad pathway investig involv tgf induc cd upregul result show knockdown cd led reduct af cell mediat collagen gel contract downregul versican smooth muscl protein sm upregul scleraxi tgf induc cd upregul signific block inhibit tgf receptor alk partial inhibit shrna smad smad protein kinas b akt inhibitor interest inhibit extracellular signal regul kinas erk pathway induc cd upregul conclus cd shown crucial maintain cell contractil human af cell vitro furthermor tgf upregul cd via alk signal cascad partial smad smad akt pathway wherea erk shown potenti negat modul find suggest cd potenti use function marker af repair strategi | D000070616;D051929;D016212 | T129;T023;T116;T123 |
34,662,463 | sar cov wastewat mean non human primat lifetim face global pandem novel coronavirus diseas world chang result howev human affect pandem scale closest relat non human primat nhps encount research sanctuaryzoo employe tourist also potenti risk contract virus human due similar genet suscept anthropozoonosi transmiss diseas human speci occur histor result infect nhps human pathogen led disastr outbreak recent studi assess suscept nhps predict catarrhin primat lemur potenti high suscept infect sever acut respiratori syndrom coronavirus sar cov virus accumul evid new factor consid spread virus fecal oral transmiss virus detect watersh countri underdevelop infrastructur raw sewag enter environ direct without process may expos nhps anim sar cov wastewat contact address concern discuss recent evid overal suggest risk transmiss sar cov via wastewat low nonetheless track viral rna wastewat provid uniqu test approach help protect nhps zoo wildlif sanctuari one health approach go forward perhap best way protect anim novel virus way would protect | D000086382;D000086402 | T047;T005;T067 |
34,662,462 | rang wide indic african great ape densiti distribut speci distribut influenc process occur multipl spatial scale therefor insuffici model speci distribut singl geograph scale provid necessari understand determin factor instead multipl approach need differ spatial extent grain research object present first attempt model contin wide great ape densiti distribut use site level estim african great ape abund identifi socioeconom environment factor drive densiti continent scale predict rang wide great ape densiti collat great ape abund estim site defin pseudo absenc site repres addit absenc locat latter base locat unsuit environment condit great ape exist literatur compil seven socioeconom environment covari layer fit general linear model investig influenc great ape abund use akaik weight averag full subset model predict rang wide densiti distribut african great ape year great ape densiti lowest high human footprint gross domest product valu highest predict densiti central africa lowest west africa total predict popul found intern union conserv natur categori ii protect area countri estim abund larg line previous studi four countri central african republ democrat republ congo liberia south sudan estim popul excess high propos improv model overcom survey predictor data limit would enabl tempor dynam approach monitor great ape across rang base key indic | D015186 | T015 |
34,662,461 | temperatur exudativori driver marmoset callithrix spp daili activ period primat affect fluctuat ambient temperatur most thermoregulatori cost chang avail food present studi investig whether ambient temperatur proxi food avail affect activ period marmoset callithrix spp predict colder site marmoset would spend time sleep site ii midday rest bout would longer hotter site iii onsetcess activ rest behavior midday would close relat temperatur food avail iv high exudativor group would higher total level rest compil data onset cessat activ time spent rest midday seven marmoset studi site wide rang temperatur use general linear mix model verifi relationship depend variabl lag dawn onset activ lag cessat activ dusk proport rest midday minimum maximum temperatur respect studi site togeth proxi food avail exudativori rate amount habitat avail per individu net primari product use sampl month sampl unit ident studi categor random factor colder site colder month marmoset left sleep tree later morn ceas activ earlier hotter site hotter month spent time rest midday exudativor group becom activ later morn also ceas activ later abund food affect time activ provid evid low high temperatur affect marmoset activ activ period appear influenc thermal environ food avail | D002144;D017753 | T070;T015;T082 |
34,662,459 | vx mitig diseas mous model autosom domin polycyst kidney diseas bear rc human mutat autosom domin polycyst kidney diseas adpkd associ format renal cyst devis therapeut approach base revers cyst phenotyp secret absorpt use vx modul cystic fibrosi transmembran regul traffick process goal test vx rcrc mice bear rc human mutat demonstr therapeut potenti found month age rcrc mice larg cyst impair renal function treat vx age month month cyst area reduc group suggest vx shrunk previous exist cyst month treatment cyst size lower untreat anim age co local studi confirm cystic fibrosi transmembran conduct regul cftr found predomin apic membran untreat anim age group consist role cl secret vx treatment basolater membran co local cftr increas fold accompani decreas fold apic co local indic vx alter phenotyp favor fluid absorpt sodiumhydrogen exchang epitheli sodium channel found normal kidney apic membran almost absent cyst vx restor level toward normal hsp high express rcrc mice lower toward normal vx demonstr cyst reduct improv renal function generat absorpt phenotyp strong support therapeut potenti vx treatment adpkd show anim model slowli progress cyst format typic human adpkd vx reduc growth alreadi establish cyst magnitud effect rcrc mous model compar previous experi use mous model evalu tolvaptan indic cftr modul warrant develop treatment adpkd | D007668 | T023 |
34,662,458 | associ time therapeut inr length stay follow mechan heart valv surgeri warfarin oral anticoagul approv use follow mechan valv surgeri mev patient may experi prolong hospit length stay los follow mev await appropri warfarin effect aim determin whether associ exist time achiev first therapeut intern normal ratio inr los follow mev | D000925;D006351 | T023;T121 |
34,662,456 | predictor earli late mortal treatment earli gastric cancer although mani patient earli gastric cancer egc die non gastric cancer relat caus associ risk categori lymph node metastasi lnm caus mortal remain unclear aim clarifi predictor earli late mortal separ | D013274 | T191 |
34,662,455 | trade off make intervent heart surgeon current generat heart surgeon experienc grow constern introduct call disrupt transcathet procedur seem threaten stabil even exist contemporari cardiovascular surgeri provid commentari report compar outcom transcathet therapi convent surgeri throughout differ scenario evolv superior surgic techniqu upfront conclus surgeon strive keep surgic skill downfal surgeri anticip reveal hold ground forese futur | D019918;D066231 | T097;T061 |
34,662,454 | fur feather friend attach zookeep anim care keeper anim relationship kar appear import zoo sinc enhanc well anim keeper make anim husbandri easier convers might risk inappropri habitu anim possibl risk safeti keeper therefor import know variabl involv relationship format use modifi version lexington attach pet scale lap measur strength kar keeper anim care zoo home lap questionnair complet keeper differ collect across three countri lap score attach zoo anim za signific lower pet anim pa signific differ za score differ taxa signific taxon differ pa score signific differ za pa score differ collect femal respond score high male za pa multipl regress reveal locat gender time spent anim signific predictor za gender taxon signific predictor pa conclud pa score compar general public reflect strong attach keeper pet za score although also reflect attach influenc differ institut cultur | D000822;D001841 | T054;T090 |
34,662,452 | compar efficaci five surgic method treatment mitral regurgit systemat review network meta analysi studi compar effect differ surgic method treatment mitral regurgit mr adult use network meta analysi method provid refer clinic select best surgic scheme | D019918;D008944 | T047;T061 |
34,662,451 | frozen eleph trunk procedur complex aortic arch surgeri salerno experi thoraflex hybrid report earli clinic outcom frozen eleph trunk fet techniqu treatment complex aortic diseas transit convent eleph trunk | D000784;D017545;D019917 | T047;T061;T046 |
34,662,449 | cirrhosi regress associ improv clinic outcom patient nonalcohol steatohepat surrog endpoint predict complic necessari assess approv nash therapi assess associ histolog noninvas test nit fibrosi liver relat complic patient nash cirrhosi | D008103;D065626 | T047 |
34,662,448 | corticosteroid use ard applic evolv therapeut coronavirus diseas covid systemat review data regard use corticosteroid treatment acut respiratori distress syndrom ard conflict coronavirus diseas covid pandem progress literatur support use corticosteroid covid non covid ard emerg glucocorticoid propos attenu inflammatori respons prevent progress fibroprolif phase ard multipl mechan anti inflammatori properti purpos systemat review comprehens evalu literatur surround corticosteroid use ard non covid covid addit narrat review clinic consider corticosteroid use patient popul ovid medlin embas search random control trial evalu use corticosteroid covid non covid ard adult patient mortal outcom includ risk bias assess risk bias tool studi identifi met inclus criteria includ total patient studi includ review report mortal benefit studi benefit seen vari time point mortal follow icu surviv hospit day covid non covid ard studi two non covid trial assess lung injuri score improv found corticosteroid led signific improv corticosteroid use number mechan ventil free day signific found increas use corticosteroid four studi assess outcom corticosteroid associ improv mortal ventil free day critic ill patient covid non covid ard evid suggest use encourag set howev due substanti differ corticosteroid regimen util trial question still remain regard optim corticosteroid agent dose durat patient ard | D000305;D000086382;D012128 | T047;T121;T109;T125;T067 |
34,662,447 | aqueous metabolom tissu specif condit pten knockout mous prostat cancer tramp neuroendocrin carcinoma metabol reprogram recogn hallmark cancer prostat specif phosphatas tensin homolog delet chromosom pten gene condit knockout ko mous carcinogenesi model high desir studi prostat cancer biolog prevent due close resembl primari molecular defect histopatholog featur human prostat cancer recent publish macromolecular profil model proteom transcriptom denot preemin inflamm myeloid suppress immun cell featur perform metabolom analys pten ko prostat versus wild type wt counterpart discern chang aqueous metabolit contrast tramp neuroendocrin carcinoma neca | D018278;D011467;D011471 | T191;T023 |
34,662,446 | threat us percept loneli divid communiti urban rural area covid loneli becom recognis import social issu health well consequ recent ongo covid pandem like impact loneli increas social isol though effect may vari across urban rural locat dynam social capit communiti cohes communiti divid like differ paper consequ examin differ compound impact isol disast bushfir pandem social capit loneli urban rural area australia articl compar experi loneli ruralregion urban area australia move aftermath bushfir covid pandem semi structur interview provid complex insight loneli experienc across differ locat key find includ higher sens social divid exacerb loneli rural communiti higher level loneli among particip live alon either area conclud loneli experienc extens among singl andor live alon regardless geograph locat | D000086382;D000075485 | T058;T047;T067 |
34,662,445 | thromboembol bleed risk edoxaban patient pacemak cardiac monitor procedur outcom global emit program limit data publish manag direct oral anticoagul insert pacemak cardiac monitor devic studi describ manag outcom edoxaban direct oral factor xa inhibitor patient undergo pacemak monitor devic implant routin clinic practic | D058409;D010138 | T074 |
34,662,443 | cancer specif surviv radic prostatectomi versus extern beam radiotherapi high risk high risk african american prostat cancer patient test differ cancer specif mortal csm rate radic prostatectomi rp vs extern beam radiotherapi ebrt nation comprehens cancer network nccn high risk african american patient well john hopkin univers jhu high risk high risk patient | D011468;D011471;D011878;D018570 | T191;T061;T058;T080;T062 |
34,662,442 | renal hemofiltr prevent metabol acidosi reduc inflamm normotherm machin perfus vascular composit allograft preclin studi recent experiment evid suggest normotherm machin perfus vascular composit allograft result improv preserv compar static cold storag less reperfus injuri immedi post oper period howev metabol acidosi common featur vascular composit allograft perfus primarili due inabl process metabol product evalu impact combin limb kidney perfus marker metabol acidosi inflamm porcin model | D064595 | T023 |
34,662,441 | glycoform human prostat specif membran antigen psma human cell prostat tissu n glycosyl ubiquit variabl posttransl modif regul physiolog function secretori membran associ protein dysregul glycosyl pathway often associ cancer growth metastasi prostat specif membran antigen psma establish biomark prostat cancer imag therapi | D011134;D011467;D011471 | T191;T023;T121;T109 |
34,662,440 | use contracept risk inflammatori bowel diseas nest case control studi contracept formul dose durat therapi mode deliveri affect risk inflammatori bowel diseas ibd poor describ | D003093;D003424;D015212 | T047 |
34,662,439 | lipoprotein z hepatotox lipoprotein predict outcom alcohol associ hepat lipoprotein z lp z abnorm free cholesterol fc enrich ldl like particl discov patient cholestat liver diseas studi aim defin diagnost valu lp z alcohol associ hepat ah interrog biolog behind format | D058625;D006519 | T047 |
34,662,438 | n acetylgalactosaminyltransferas protect hepat ischemiareperfus injuri block apoptosi signal regul kinas n termin dimer ischemia reperfus ir injuri inevit complic liver transplant lt compromis prognosi glycosyltransferas recogn promis target diseas therapi role remain open studi hepat ir hir injuri aim demonstr exact function molecular mechan glycosyltransferas n acetylgalactosaminyltransferas galnt hir injuri | D008099;D048848;D017350;D015427 | T116;T023;T126;T037 |
34,662,437 | incid psycho social well rural communiti south africa articl explor incid psychosoci well within lokaleng rural communiti locat north west provinc south africa communiti uniqu share similar mani rural communiti south africa depriv various resourc impoverish indic need explor incid psychosoci well communiti research phenomenon communiti specif quantit cross section design employ purpos sampl adult communiti member n complet batteri valid questionnair data analyz ibm spss statist softwar packag result indic sampl experienc lower level psychosoci well support similar find south african studi rural communiti tend report lower level psychosoci well | D044383;D012424 | T098;T102 |
34,662,436 | determin compens patient hepat b virus relat decompens cirrhosi start antivir therapi despit antivir therapi liver function often fail recov patient hepat b virus hbv relat decompens cirrhosi | D006509;D019694 | T047 |
34,662,435 | characterist propos mechan qrs morpholog observ left bundl branch pace procedur perform left bundl branch pace lbbp various qrs morpholog observ lead penetr ventricular septum vs studi aim evalu characterist infer mechan under qrs morpholog | D004567 | T073 |
34,662,434 | resist sar cov beta gamma variant plasma collect canadian blood donor spring pilot studi assess abil plasma collect canadian blood donor first wave sar cov pandem neutral later sar cov variant concern voc | D001782;D000086382;D000086402 | T047;T098;T005;T061;T067 |
34,662,433 | plan ct guid robust fast cone beam ct scatter correct use local filtrat techniqu cone beam ct cbct wide util imag guid radiotherapi plan ct pct aid cbct scatter correct could enhanc imag qualiti extend cbct applic dose calcul adapt plan nevertheless exist pct base approach demand accur registr pct cbct lead limit imag perform increas comput cost larg anatom discrep exist work propos robust fast cbct scatter correct method use local filtrat techniqu rigid registr pct cbct lf rr | D054893;D061089 | T061;T060 |
34,662,432 | blood testosteron level sick health male chimpanze testosteron level decreas face immun challeng integr part immun respons testosteron secret inhibit individu confront immun challeng testosteron mediat physiolog morpholog behavior trait compromis time impair health nevertheless male speci seem maintain high level testosteron confront immun challeng uphold competit strength compromis immun respons argu phenomenon occur speci live social system high degre male male competit mate opportun male chimpanze contest access fertil femal domin sire major offspr male mate pattern make chimpanze candid speci could expect male maintain high testosteron level compromis immun respons ensur immedi reproduct success measur blood testosteron level male femal chimpanze express clinic symptom symptomat show evid clinic diseas assess asymptomat femal expect find lower testosteron level symptomat individu asymptomat subject male would predict lower testosteron level symptomat individu asymptomat male immun respons lead decreas testosteron secret altern male could equal level testosteron symptomat asymptomat uphold competit strength result show male chimpanze exhibit lower level testosteron confront immun challeng asymptomat suggest male testosteron secret suppress part immun respons potenti increas surviv lifetim reproduct success howev negat impact momentari competit abil also male may employ differ mate strategi less testosteron driven eg affili strategi consequ individu cost maintain high testosteron level may outweigh potenti gain reproduct success | D002679;D012726 | T015;T054 |
34,662,429 | real world evid age independ electroconvuls therapi efficaci retrospect cohort studi electroconvuls therapi ect effect treatment depress disord approv use adolesc adult unclear whether efficaci cognit side effect burden differ age effect usual clinic practic match prospect studi examin effect ect depress cognit larg clinic cohort | D004565 | T061 |
34,662,428 | toward predict photosynthet effici biomass gain crop genotyp field season photosynthesi acclim quick fluctuat environ order optim absorpt sunlight energi specif photosynthet photon fluenc rate ppfr fuel plant growth convers effici intercept ppfr photochem energi e biomass c critic paramet describ plant product time howev mask link instantan photochem energi uptak specif condit oper effici photosystem ii fqfm biomass accumul therefor identif energi thus resourc effici genotyp chang environment condit imped long term monitor fqfm canopi level soybean glycin max l merr maiz zea may genotyp greenhous field condit use autom chlorophyl fluoresc spectral scan fqfm deriv incid sunlight entir grow season model base genotyp interact differ environment variabl allow us cumul photochem energi uptak thus estim e noninvas e rang depend genotyp photochem energi transduc biomass effici c maiz genotyp strike e correl shoot biomass seven independ experi vari condit r thus estim biomass product integr photosynthet respons environment stress grow season identifi energi effici genotyp great potenti improv crop growth model estim product breed line whole ecosystem time point use autonom measur system | D018533 | T081 |
34,662,427 | trend mental health symptom servic use unmet need servic among us adult first month covid pandem covid pandem led rise morbid mortal social econom disrupt like impair mental health purpos studi track trend mental health symptom use servic unmet need servic among us adult delin variat across demograph strata data drawn us household puls survey repeat cross section onlin survey collect april novemb us adult weight repres us popul survey respond self report symptom anxieti depress use medic counsel servic unmet need servic report probabl anxieti depress rose signific studi period preval rate respect novemb rate four time higher earli us norm use prescript medic counsel servic unmet need mental health servic also rose signific preval rate probabl mental health disord highest among young less educ singl parent femal black multi racial respond vacil dispar cohort young femal moder educ respond also report higher unmet need servic dispar estim mental health disord mental health treatment indic strike disequilibrium potenti need use mental health servic covid pandem rise mental health challeng born larg young less advantag peopl color women potenti expand interrupt optim function societ recoveri covid | D000086382 | T047;T067 |
34,662,426 | posit select horizont gene transfer genom male kill wolbachia wolbachia genus widespread bacteri endosymbiont strain hijack manipul arthropod host reproduct male kill one manipul matern transmit bacteria benefit surviv daughter part remov competit son scarc resourc despit previous find interest genom featur microbi sex ratio distort popul genom male killer remain larg uncharacter uncov sever uniqu featur genom popul genom four arizonan popul male kill wolbachia strain winn infect mushroom feed drosophila innubila first compar winn genom close relat wolbachia genom drosophila host term genom content confirm winn genom larg similar overal gene content wmel strain infect melanogast howev also contain mani uniqu gene repetit genet element indic later gene transfer winn non drosophila eukaryot also find line literatur preced gene wolbachia prophag octomom region posit select gene posit select mani also show evid recent horizont transfer among wolbachia symbiont genom dynam select horizont gene transfer across genom sever wolbachia strain divers host speci may import under factor wolbachia success male killer diverg host speci | D020577 | T007 |
34,662,425 | origin adapt evolut uv resist locus mediat signal plant terrestri uv resist locus uvr mediat photomorphogen respons acclim uv b radiat regul transcript seri transcript factor tfs howev origin evolut uvr mediat signal pathway remain larg unknown studi investig origin evolut major compon uvr mediat signal pathway uvr repressor uv b photomorphogenesi rup bri em suppressor bes bes interact myc like bim wrki dna bind protein wrki myb domain protein mybmybmyb phytochrom interact factor pif pif use compar genom phylogenet approach show central regul uvr present conserv evolutionari rout plant evolut evolutionari histori downstream negat regul tfs differ green plant phylogeni canon uvr constitut photomorphogen cop suppressor phya spa elong hypocotyl hy rup signal pathway origin chlorophyt confer green alga addit abil cope uv b radiat moreov emerg multipl uvr mediat signal pathway charophyt laid foundat cross talk uv b signal endogen hormon respons import observ signatur reflect plant adapt high uv b irradi subaerialterrestri environ includ posit select uvr rup increas copi number vital tfs result reveal green plant experienc adapt modif canon uvr copspa hy rup signal pathway also diversifi uv b signal transduct mechan increas cross talk pathway associ brassinosteroid auxin studi great expand understand molecular evolut adapt mechan under plant uv b acclim | D019143;D010802;D014466 | T070;T062;T038;T078 |
34,662,423 | age men insuffici vitamin higher mortal risk ad valu free fraction activ form low total hydroxyvitamin oh associ mortal whether vitamin free form dihydroxyvitamin oh provid addit inform unclear | D009026 | T081 |
34,662,422 | clinic practic pattern among health care profession instrument assist soft tissu mobil instrument assist soft tissu mobil iastm popular myofasci intervent use health care profession | D010818;D013177 | T057;T056 |
34,662,421 | preoper psychosoci factor short term pain function recoveri hip arthroscopi femoroacetabular imping syndrom low mental health score depress anxieti associ wors pain function outcom hip arthroscopi patient femoroacetabular imping syndrom fai preoper screen psychosoci factor self efficaci kinesiophobia pain catastroph may aid identifi patient risk poorer outcom | D057925 | T046 |
34,662,420 | progress rehabilit profession soccer player anterior cruciat ligament reconstruct phase clinic perspect video demonstr outlin case success rehabilit romanian first divis soccer player sustain anterior cruciat ligament acl ruptur menisc tear competit season ligament reconstruct autolog hamstr graft partial meniscectomi perform player return level competit month remain level free knee injuri present year later base postop phase propos royal dutch societi physic therapi propos clinic progress exercis video demonstr address bodi function structur level activ particip phase object achiev criteria need advanc phase acl rehabilit process attain | D000070598;D059549;D007718;D012916 | T056;T061;T037 |
34,662,417 | high school adopt evid base practic manag exert heat stroke exert heat stroke eh death prevent adher best practic | D018883;D013177 | T056;T037 |
34,662,416 | co evolutionari signal identifi burkholderia pseudomallei surviv strategi hostil environ soil bacterium burkholderia pseudomallei causat agent melioidosi signific caus human morbid mortal mani tropic subtrop countri speci notori surviv harsh environment condit genet architectur adapt remain unclear employ power combin genom wide epistasi co select studi genom condit wide transcriptom analys divers condit gene knockout assay uncov signal co select combin genet marker repeat select togeth b pseudomallei evolut enabl us identifi mutat pair co select distinct gene noncod rna gene co select display mark express correl b pseudomallei subject physic stress condit highlight condit one major evolutionari drive forc bacterium identifi putat adhesin bpsl hub co select signal experiment confirm bpsl role nutrient depriv explor function basi co select gene network surround bpsl facilit bacteri surviv nutrient deplet find suggest nutrient limit condit common select pressur act speci allel variat bpsl may promot b pseudomallei surviv harsh environment condit facilit bacteri adher differ surfac cell live host | D005075;D016957 | T007;T045 |
34,662,414 | modular evolut drosophila metabolom compar phylogenet studi offer power approach studi evolut complex trait although much effort devot evolut genom organism phenotyp relat littl work done evolut metabolom despit fact compos basic structur function build block organ explor variat metabolit level across evolut genus drosophila employ common garden design measur metabolom within among speci drosophila find sex age dramat evolutionarili conserv effect metabolom also find substanti evid mani metabolit pair covari phylogenet correct metabolom coevolut modular modul enrich specif biochem pathway show differ evolutionari trajectori show sign stabil select observ suggest function relationship may ultim caus modular coevolutionari pattern also differ sex affect age explor relev modular evolut fit associ modul lifespan variat measur common garden find sever modul associ lifespan particular metabolom older fli oxaloacet level older femal appear coevolv lifespan lifespan associ modul older femal suggest metabol associ could underli lifespan evolut | D004330;D055442 | T070;T204;T039 |
34,662,411 | embed popul health physic therapist profession educ futur health care profession educ move focus individu embrac health larger societi covid pandem highlight connect social determin health popul framework compet support deliveri popul health content entri level doctor physic therapi dpt curriculum three option integr popul health content dpt curriculum present thread content throughout curriculum concentr content identifi cours offer elect cours strategi benefit challeng thread content throughout curriculum provid best opportun reinforc popul health compet across popul practic set experienti learn use authent scenario provid ideal opportun student understand popul health concept real world context activ incorpor interact health profess broaden student perspect role differ profess achiev popul health goal exampl learn activ includ compet area foundat popul health prevent health promot health polici current societ issu provid opportun enhanc popul health educ meaning perspect student topic health equiti present opportun tie social polit factor popul health social justic health outcom similar covid pandem put issu mental health health dispar health system front center understand popul health | D000086382;D004517;D059825;D000075485 | T065;T047;T097;T067;T058 |
34,662,410 | distinguish earli pattern physic activ goal attain weight loss onlin behavior obes treatment use latent class analysi physic activ pa goal adher consist associ greater weight loss behavior obes treatment earli weight loss respons predict futur weight loss success howev remain unclear behavior initi week treatment distinguish respond nonrespond might effect target improv treatment outcom character subgroup distinct pattern pa goal adher initi month onlin group base weight control program determin associ pattern month weight loss particip receiv onlin behavior obes intervent pa goal daili self monitor week adher step goal moder vigor pa mvpa minut goal base self monitor record examin use latent class analysi bodi weight object measur month particip n femal raceethn minor mean bodi mass index kgm cluster three subgroup base earli goal attain pa goal mvpa goal neither pa goal pa goal class signific greater month weight loss estim mean weight loss ci compar mvpa goal neither pa goal class individu meet pa goal earli treatment achiev greater weight loss meet mvpa step goal point need explor factor associ nonadher pa goal better understand potenti target treatment refin adapt intervent | D005006;D006040 | T170;T098;T102 |
34,662,409 | cumul incid sar cov infect among adult georgia unit state august decemb report coronavirus diseas covid case underestim true sever acut respiratori syndrom coronavirus sar cov infect data infect includ asymptomat infect need minim bias estim report case seropreval survey conduct household base probabl survey estim cumul incid sar cov infect adjust antibodi wane | D000086382 | T047;T067 |
34,662,404 | stress distress potenti underpin exercis relat inspiratori distress adolesc sport perform mani adolesc sport perform present exercis relat respiratori symptom consist exercis induc laryng obstruct eilo pathogen underpin eilo fulli resolv exist behavior manag includ therapi target laryng physiolog wherea surgic intervent target laryng anatom anomali recent find research clinic practic indic psycholog stress thorac breath co occur laryng tight adolesc sport perform eilo perspect articl theoriz potenti coexist discuss possibl underpin respiratori symptom includ eilo thorac breath adolesc sport perform consid effect various stressor adolesc sport perform expos impact may breath includ term laryng narrow effect stress breath examin light reciproc communic brain bodi relationship psycholog stress stress respons respiratori system mediat autonom nervous system inform decis make clinic awar area may worth expand focus target main laryng structur also includ constrict airway effect thorac breath larynx exercis import consid respiratori distress multidimension perspect incorpor complex sport perform psycholog physic experi manag health well emphas | D000402;D007818;D012128;D000067009 | T047;T056;T046 |
34,662,403 | orthoscop phylogenet pipelin infer gene histori genom wide data compar genom scale analys protein code gene sequenc employ examin evid whole genom duplic horizont gene transfer purpos orthogroup delin infer evolutionari histori regard gene result orthogroup analys need integr infer genom scale histori orthogroup set gene descend singl gene last common ancestor speci consider howev analys confront sever problem analyt pipelin infer gene histori method compar speci gene tree fulli develop without detail analys within orthogroup evolutionari event paralog gene orthogroup distinguish genom wide integr result deriv multipl orthogroup analys present analyt pipelin orthoscop star infer evolutionari histori animalpl gene genom scale data orthoscop estim tree specifi gene detect speciationgen duplic event occur node belong one lineag lead speci interest integr result deriv gene tree estim queri gene genom wide data thus orthoscop use detect speci node whole genom duplic first step compar genom analys moreov examin presenc absenc gene belong speci lineag dens taxon sampl avail orthoscop web version orthoscop detect gene lost specif lineag horizont gene transfer pipelin avail https githubcomjun inoueorthoscopestar | D020440;D016678 | T028;T045 |
34,662,402 | detect neanderth adapt introgress genet variant modul report gene express human immun cell although variat introgress neanderth undergon select sweep littl known function signific use massiv parallel report assay mpra assay high frequenc introgress variant abil modul gene express within bp endogen sequenc identifi variant activ putat cis regulatori element cres express modul variant emvar emvar predict alter bind motif import immun transcript factor enrich associ neutrophil white blood cell count associ express gene function innat immun pathway includ inflammatori respons antivir defens combin mpra data data set identifi strong candid driver variant posit select includ emvar may contribut protect sever covid respons endogen delet two cres contain express modul variant link immun function rs rs identifi primari genic target elmsan pan stat respect three gene differenti express influenza infect overal present first databas experiment identifi express modul neanderth introgress allel contribut potenti immun respons modern human | D014644;D015894;D059125 | T070;T015;T028 |
34,662,401 | advanc enzym mediat proxim label potenti plant research cellular process reli intim interplay differ molecul includ dna rna protein metabolit obtain integr data abund dynam high tempor spatial resolut essenti understand plant growth develop past decad enzymat proxim label pl emerg power tool studi local protein nucleotid ensembl discov protein protein protein nucleotid interact resolv question protein local membran topolog ever grow number continu improv enzym method keep broaden spectrum possibl applic pl make access differ organ includ plant initi pl experi plant requir high express level long label time recent develop faster enzym enabl pl protein cell type specif level even low abund bait differ plant speci moreov expand use pl addit purpos identif locus specif gene regul high resolut electron microscopi may reach review give overview current avail pl enzym applic mammalian cell cultur plant discuss challeng limit pl method highlight open question possibl futur direct pl plant | D018521;D012107 | T096;T039;T170;T169;T081;T040;T062 |
34,662,399 | flavonoid naringenin chalcon naringenin dihydrotricin tricin lignin monom papyrus recent studi demonstr sever polyphenol compound produc beyond canon monolignol biosynthet pathway behav lignin monom particip radic coupl reaction incorpor lignin polym show various class flavonoid chalconoid naringenin chalcon flavanon naringenin dihydrotricin flavon tricin incorpor lignin polym papyrus cyperus papyrus l rind flavonoid releas rind lignin derivat follow reduct cleavag dfrc chemic degrad method cleav ether linkag indic least fraction integr lignin ether link structur due particular structur tricin dihydrotricin whose c c posit b ring occupi methoxi group compound incorpor lignin bond howev naringenin chalcon naringenin substitu posit therefor form addit carbon carbon linkag includ linkag form phenylcoumaran structur suscept cleavag dfrc furthermor nuclear magnet reson analysi indic naringenin chalcon also form addit linkag conjug doubl bond discoveri expand rang flavonoid incorpor natur lignin broaden tradit definit lignin enhanc premis phenol compound present cell wall lignif could oxid potenti integr lignin structur depend chemic compat studi indic papyrus lignin uniqu structur lignin known date integr divers phenol compound differ class flavonoid discoveri open new way engin design lignin specif properti enhanc valu | D001665;D015394 | T192;T085 |
34,662,398 | virtual assist lung map sublobar resect small pulmonari nodul long term result short term efficaci virtual assist lung map val map preoper bronchoscop multi spot lung mark techniqu confirm prospect multicentr studi object studi analys local recurr surviv patient enrol studi long term | D008175;D055613 | T033;T191 |
34,662,396 | effect autom unit dose dispens barcod scan medic administr error uncontrol studi medic administr error mae occur frequent hospit may compromis patient safeti prevent strategi need reduc risk mae | D008510;D004364 | T074;T121 |
34,662,395 | role left atrial appendag occlus patient heartmat left atrial appendag occlus laao time implant may reduc thromboembol event tes continu flow left ventricular assist devic support heartmat hm reduc tes overal efficaci laao hm unknown | D020517;D001281;D002545;D020521 | T047;T023;T046 |
34,662,394 | age evolutionari crossroad longitudin gene co express network analys proxim ultim caus age bat organ tissu cell age remain challeng issu although research identifi multipl mechanist caus age three major evolutionari theori develop unravel ultim caus organism age central hypothesi theori strength natur select decreas age howev empir evid organ age phylogenet limit especi natur popul develop generic comparison gene co express network quantifi dissect heterogen gene co express conspecif individu differ age class provid topolog evid mechan fundament caus organism age appli approach investig complex proxim ultim caus age phenotyp natur popul greater mous ear bat myoti myoti remark long live speci given bodi size metabol rate avail longitudin blood transcriptom myoti gene co express network becom increas fragment age suggest eros strength natur select general dysregul gene co express age bat howev select pressur remain suffici strong allow success emerg homogen age specif gene co express pattern least year thus older individu long live speci appear sit evolutionari crossroad age experi decreas strength natur select target select specif biolog process invit refin central hypothesi evolutionari age theori | D005075;D012641 | T070;T045 |
34,662,392 | express profil glp receptor gastrointestin tract pancrea adult femal mice therapi base glucagon like peptid receptor glp r agon high effect treat type diabet obes local glp rs mediat antidiabet possibl action glp still debat purpos studi identifi site glp r mrna protein express mous gastrointestin system mean glp r antibodi immunohistochemistri glpr mrna fluoresc situ hybrid exendin autoradiographi expect glp r stain observ almost cell pancreat islet rare cell stomach glp r stain found exclus gastric corpus mucous neck cell known protect stomach mucosa brunner gland strong stain glp r pretreat glp agonist exendin caus intern receptor mucin secret pretreat phosphat buffer salin antagonist exendin intestin mucosa glp r stain observ intraepitheli lymphocyt lamina propria lymphocyt enteroendocrin cell contain secretin peptid yy somatostatin cholecystokinin glp r stain seen nerv fiber within cholin acetyl transferas nitric oxid posit myenter plexus gastric corpus distal larg intestin strongest mid hindgut area final intraperiton administr radiolabel exendin strong label myenter fiber conclus studi expand knowledg glp r local suggest glp may serv import role modul gastrointestin health mucos protect | D020869 | T059;T063 |
34,662,391 | characterist outcom patient postop candida versus bacteri mediastin case match compar studi postop mediastin fear complic cardiac surgeri associ high mortal especi critic ill patient candida speci infect rare sever poor known outcom conduct case control studi describ characterist manag outcom patient postop candida mediastin | D002177;D008480 | T047 |
34,662,390 | effect bntbmrna covid vaccin patient hematolog neoplasm nationwid mass vaccin set evid regard effect covid vaccin patient impair immun limit initi observ suggest lower humor respons patient evalu relat effect mrna bntb vaccin patient hematolog neoplasm compar match control data patient hematolog neoplasm vaccin dose extract match vaccin control subpopul analys focus patient receiv therapi hematolog neoplasm patient without treatment follow recipi specif treatment analysi focus covid outcom day second vaccin dose area document covid infect polymeras chain reaction symptomat infect hospit sever covid diseas covid relat death popul million insur peopl patient hematolog neoplasm identifi receiv therapi activ diseas vaccin patient hematolog neoplasm compar vaccin match control increas risk document infect relat risk rr ci symptomat covid rr ci covid relat hospit rr ci sever covid rr ci covid relat death rr ci limit analysi patient hematolog treatment show higher increas risk analysi show vaccin patient hematolog neoplasm particular patient receiv treatment suffer covid outcom vaccin individu intact immun system way enhanc covid immun patient popul addit dose explor | D000090982;D000086382;D019337 | T116;T047;T121;T191;T109;T129;T114;T067;T200 |
34,662,389 | mine plant endogen target mimic mirna lncrna interact base dual path parallel ensembl prune method interact microrna mirna long non code rnas lncrnas play import role biolog activ special lncrnas endogen target mimic etm bind mirna regul express target messeng rnas mrnas grow number studi focus anim studi plant scarc mani function plant etm unknown studi propos novel ensembl prune protocol predict plant mirna lncrna interact first adapt prune base model base dual path parallel ensembl method meet challeng cross speci predict potenti etm mine predict result express level rnas identifi biolog experi construct lncrna mirna mrna regulatori network function potenti etm infer enrich analysi experi result show propos protocol outperform exist method state art predictor various plant speci total potenti etm verifi biolog experi involv regul potenti etm infer gene ontolog enrich analysi involv function signific research | D035683;D062085 | T114;T123 |
34,662,388 | gender differ inform payment healthcar evid african countri inform payment widespread mani healthcar system imped access healthcar thwart progress achiev univers health coverag major element health relat sustain develop goal gender may import driver determin pay inform care studi examin particular low middl incom countri studi aim examin gender dispar pay inform healthcar africa use afrobaromet round survey data collect septemb august african countri final sampl compos adult use multipl logist regress evalu associ gender pay inform obtain healthcar result show women men report pay inform healthcar men like pay inform healthcar women african countri odd ratio confid interv irrespect age residenti locat educ attain employ status occup indic poverti make meaning progress toward improv univers healthcar coverag african countri must improv understand gender aspect inform payment healthcar act barrier access care determin poor health | D003695;D005382 | T058;T052;T093;T081 |
34,662,384 | multicent evalu new fulli autom androstenedion electrochemiluminesc immunoassay precis analysi method comparison determin refer rang androstenedion asd level aid diagnosi hyperandrogen togeth clinicallaboratori find evalu perform new autom elecsi asd assay vs asd isotop dilut liquid chromatographi tandem mass spectrometri id lc msms refer measur procedur determin refer rang | D000735;D011085 | T047;T121;T109;T125 |
34,662,383 | aortic arch reconstruct norwood procedur use curv polytetrafluorethylen patch aortic arch enlarg norwood procedur classic carri use curv homograft patch inner curvatur neoaortic arch studi investig outcom newli use artifici patch vascular prosthesi altern homograft patch | D018636;D058327 | T047;T061 |
34,662,382 | ticagrelor monotherapi patient high bleed risk undergo percutan coronari intervent twilight hbr patient high bleed risk hbr repres preval subgroup among undergo percutan coronari intervent pci earli aspirin discontinu short cours dual antiplatelet therapi dapt emerg bleed avoid strategi aim studi assess effect ticagrelor monotherapi month dapt contemporari hbr popul | D062645 | T061 |
34,662,378 | gene express base model predict outcom children intermedi risk classic hodgkin lymphoma classic hodgkin lymphoma chl common malign children adolesc although chl high curabl treatment chemotherapi radiat often come cost long term toxic morbid effect risk stratif tool need tailor therapi use gene express profil gep investig tumor microenviron tme biolog determin molecular correl treatment failur develop outcom model prognost pediatr chl total formalin fix paraffin embed tissu biopsi patient enrol children oncolog group trial ahod use gep compar adult chl data eosinophil b cell mast cell signatur enrich children wherea macrophag stromal signatur promin adult concord previous publish model overal surviv predict adult chl valid pediatr chl therefor develop cellular compon model reflect tme composit predict event free surviv ef independ valid cohort observ signific differ weight year ef high risk low risk group vs log rank p independ interim respons stage fever albumin demonstr uniqu diseas biolog children adolesc har risk stratif diagnosi trial regist wwwclinicaltrialsgov nct | D020869 | T059;T063 |
34,662,377 | high risk subtyp chronic lymphocyt leukemia detect earli year prior diagnosi chronic lymphocyt leukemia cll preced monoclon b cell lymphocytosi mbl cll precursor state preval age individu howev durat mbl mechan evolut cll remain larg unknown studi sequenc b cell receptor bcr immunoglobulin heavi chain igh gene repertoir patient cll match control blood sampl taken year prior diagnosi signific skew bcr igh gene repertoir detect major patient even occurr lymphocytosi irrespect clonotyp igh variabl gene somat hypermut status furthermor identifi domin clonotyp belong major stereotyp subset associ poor prognosi year diagnosi patient cll patient longitudin sampl skew bcr igh gene repertoir increas signific time diagnosi remain stabl high level patient avail sampl diagnosi cll clonotyp alreadi present prediagnost sampl overal data indic preclin phase cll could longer previous thought even advers prognost case | D015451;D008218 | T191;T047 |
34,662,373 | develop plasma biomark diagnost model incorpor ultrasensit digit immunoassay screen strategi alzheim diseas chines popul ultrasensit detect blood base biomark amyloid tau neurofila light nfl drawn much attent alzheim diseas ad diagnosi howev studi conduct chines popul studi aim evalu abil plasma biomark diagnost model ad chines popul base novel digit immunoassay technolog | D000544 | T048;T047 |
34,662,372 | integr divers data sourc predict diseas risk dairi cattl machin learn approach livestock farm current undergo digit revolut becom increas data driven yet data often resid disconnect silo make imposs leverag full potenti improv anim well introduc precis livestock farm approach bring togeth inform stream varieti life domain dairi cattl studi whether includ divers data sourc improv qualiti predict eight diseas whether use complex predict algorithm extent compens less divers data use three machin learn approach vari complex logist regress gradient boost tree train data anim herd austria show predict lame acut chronic mastiti anestrus ovarian cyst metriti ketosi hyperketonemia periparturi hypocalcemia milk fever routin avail data give encourag result exampl predict lame high sensit specif f analysi import individu variabl predict perform show diseas dairi cattl product complex interplay multitud life domain hous nutrit climat includ divers data sourc increas predict perform reus exist data creat action inform prevent intervent find pave way toward data driven point care intervent demonstr ad valu integr avail data dairi industri improv anim well reduc diseas risk | D002418;D007662 | T033;T047;T046 |
34,662,371 | three dimension movement distribut cryptolest ferrugineus coleoptera laemophloeida adult store wheat constant temperatur moistur content understand movement distribut insect insid grain bin crucial develop effect store grain manag protocol three dimension movement distribut adult cryptolest ferrugineus stephen c determin intern dimens wooden box fill wheat uniform moistur content wet basi wheat constant moistur content fill mesh cube place insid wooden box center mesh cube box one hundr adult insect introduc begin movement h mesh cube remov wooden box less min final content mesh cube siev insect count experi replic three time maximum insect stay introduc cube center wooden box introduc adult move downward introduct locat studi temperatur moistur content h studi show c ferrugineus movement three dimens follow diffus pattern horizont direct move downward due drift effect geotaxi vertic direct | D001517 | T204 |
34,662,370 | multipl myeloma cell induc lipolysi adipocyt uptak fatti acid fatti acid transport protein adipocyt occupi cellular volum within bone marrow bm wherein multipl myeloma mm origin resid howev natur interact mm cell adipocyt remain unclear cancer associ adipocyt support tumor cell various mechan includ metabol reprogram cancer cell hypothes metabol interact mediat depend mm cell bm adipocyt show bm aspir precursor state mm includ monoclon gammopathi undetermin signific smolder mm exhibit signific upregul adipogen commit compar healthi donor vitro cocultur assay reveal adipocyt induc increas mm cell prolifer monoclon gammopathi undetermin significancesmold mm compar newli diagnos mm use murin mm cellbm adipocyt cocultur assay describ mm induc lipolysi adipocyt via activ lipolysi pathway upregul fatti acid transport mm cell mediat uptak secret free fatti acid ffas adjac mm cell effect ffas mm cell dose depend reveal increas prolifer lower concentr vs induct lipotox higher concentr lipotox occur via ferroptosi pathway exogen treatment arachidon acid long chain ffa murin plasmacytoma model display reduct tumor burden taken togeth data reveal novel pathway involv mm cell induc lipolysi bm adipocyt suggest prevent ffa uptak mm cell potenti target myeloma therapeut | D008066 | T040 |
34,662,369 | content valid nurs diagnosi powerless women natur childbirth valid content nurs diagnosi powerless women natur childbirth | D009321;D009733 | T058;T033 |
34,662,368 | move toward strategi acceler cervic cancer elimin high burden citi lesson learn amazon citi manaus brazil world health organ call elimin cervic cancer reson citi like manaus brazil burden among world highest manaus offer free cytolog base screen sinc hpv immun sinc public system constrain mani challeng perform well defin obtain cervic cancer prevent activ within manaus public health record evalu immun screen coverag screen region neighborhood annual pink octob screen campaign estim among girl boy age dose hpv vaccin higher rate age respect cytolog test perform outsid target age remain correspond target popul one third women age east zone highest screen coverag highest high grade cytolog rate lowest estim cancer compar south zone respect largest neighborhood fewer per capita screen locat result lower coverag octob clinic success achiev higher screen volum high grade cytolog rate although found evid follow within month post screen women high grade wors cytolog complet work confirm manaus success initi hpv vaccin forecast substanti cervic cancer reduct concert effort campaign clinic improv screen coverag reach high risk women screen campaign communiti locat high risk neighborhood use self collect hpv test achiev widespread coverag simplifi triag treatment fewer visit closer communiti would great improv follow program effect achiev cervic cancer elimin goal high burden citi requir major reform screen simpler follow treatment | D002583 | T191 |
34,662,367 | impact multicollinear capt modal heterogen machin learn framework comput assist french phonem pronunci train phonem pronunci usual consid basic skill learn foreign languag practic pronunci comput assist way help self direct long distanc learn environ recent research indic machin learn promis method build high perform comput assist pronunci train modal mani data driven classifi model support vector machin back propag network deep neural network convolut neural network increas wide use yet acoust waveform phonem essenti modul base vibrat vocal cord fact somehow make predictor collinear distort classifi model common use solut address issu suppress collinear predictor via partial least squar regress algorithm allow obtain high qualiti predictor weight result via predictor relationship analysi howev linear regressor classifi type possess simpl topolog structur constrain univers regressor issu paper present heterogen phonem recognit framework benefit phonem pronunci diagnost task combin partial least squar support vector machin french phonem data set contain sampl establish evalu experi experi paper demonstr new method improv accuraci perform phonem classifi compar state art differ data train data densiti | D000077321;D007802;D007858;D060388 | T171;T066;T041;T061;T081;T062 |
34,662,364 | associ tear matrix metalloproteinas immunoassay sign symptom dri eye diseas cross section studi use qualit semiquantit quantit strategi studi aim analyz associ tear matrix metalloproteinas mmp immunoassay sever dri eye de sign symptom qualit semiquantit quantit evalu immunoassay band | D007118;D036301 | T062;T059 |
34,662,362 | identifi modifi risk factor lung cancer indic mendelian random lung cancer major caus mortal tumor patient incid rate recent declin still far satisfactori potenti modifi risk factor explor | D057182 | T062 |
34,662,360 | associ nitric oxid synthas c genet polymorph chronic kidney diseas meta analysi incorpor trial sequenti analysi sever meta analys relationship endotheli nitric oxid synthas eno c gene polymorph chronic kidney diseas ckd publish howev result studi inconsist undetermin whether sampl size suffici reach definit conclus | D020641 | T086 |
34,662,359 | transpar health equiti strategi state base protocol remdesivir alloc use emerg use author eua remdesivir coronavirus diseas rais question transpar appli strategi equit alloc priorit elig patient given limit suppli medic absenc feder oversight highlight critic role state health policymak pandem | D000069576;D033181;D020407;D058873;D000086402 | T052;T073;T170;T005;T054;T067;T080 |
34,662,357 | non linear interact physic activ polygen risk score bodi mass index danish russian popul bodi mass index bmi high herit polygen trait also affect various environment behavior risk factor use bmi polygen risk score prs studi interplay genet environment factor defin bmi first generat bmi prs explain varianc bmi genet risk score grs use genom wide signific bmi associ variant r compar second analyz interact bmi prs seven environment factor found signific interact physic activ bmi prs even well known effect fto region exclud prs use small dataset sampl third stratifi studi popul two risk group use bmi prs top studi popul includ high prs risk group engag self report physic activ associ kgm decreas bmi group compar kgm decreas bmi rest popul result confirm genet background strong affect adult bmi general popul ii show non linear interact bmi genet physic activ iii provid standard framework futur gene environ interact analys | D015444;D020412 | T061;T032;T056;T045 |
34,662,356 | spatiotempor inflect point human run effect train level athlet modal effect differ train regim histori spatiotempor characterist human run evalu four group subject differ histori engag run specif train sprinter distanc runner activ athlet sedentari individu subject ran varieti veloc rang slowest fastest trial random order group averag maxim run veloc rank fastest slowest sprinter distanc runner activ athlet sedentari individu veloc cadenc step length v c relationship made plot step length cadenc veloc test analyz segment regress method util two regress line subject group critic veloc defin inflect point relationship veloc rang inflect point slower faster veloc rang veloc modul primarili alter step length alter cadenc respect pattern common observ four group sprinter distanc runner alreadi report also activ athlet sedentari individu pattern may reflect energi save strategi data group combin signific correl maxim run veloc run veloc step length inflect point spite wide varieti athlet experi subject well maximum run veloc inflect point appear similar cadenc stepss similar relat veloc vmax result impli influenc run specif train inflect point minim | D056352 | T097;T098 |
34,662,354 | role adamt vwf f gene deep vein thrombosi previous describ associ rare adamt singl nucleotid variant snvs deep vein thrombosi dvt moreov dvt patient least one rare adamt snv lower adamt activ non carrier | D020641 | T086 |
34,662,352 | psychometr evalu danish languag version field practic experi questionnair student teacher educ fpe dk use item analysi accord rasch model aim studi conduct first valid three field practic experi scale intend measur student opportun learn observ teacher practic feedback practic key teach activ field practic placement part teacher educ program scale translat adapt elementari teach candid survey develop ambiti instruct project item adapt refer teach subject student train respons scale modifi four step translat back translat strategi use subsequ danish norwegian iceland translat mutual adjust mean facilit later cross nordic studi particip danish student teacher educ program one univers colleg least one field practic placement data collect use target onlin survey one month immedi follow field placement data analys use rasch model three field experi scale fit rasch model evid overal homogen score low versus high score student local depend item dif relat level field practic campus type teacher educ program gender age reliabl scale excel subgroup target scale studi sampl good teach activ occur rare field practic ie difficult item three scale signific differ mean score depend level field practic placement thus scale expand get better coverag student opportun learn relat core teach activ present train field practic placement good psychometr properti three scale show promis futur research | D011594 | T060 |
34,662,350 | natur languag process cognit therapi extract schema thought record cognit approach psychotherapi aim chang patient maladapt schema over negat view world futur obtain awar view record thought process situat caus pathogen emot respons schema under thought record thus far larg manual identifi use recent advanc natur languag process take one step automat extract schema thought record end ask healthi particip amazon mechan turk complet five thought record consist sever utter reflect cognit process agreement two rater manual score utter respect much reflect schema substanti cohen natur languag process softwar pretrain english wikipedia articl glove embed use repres word utter map schema use k nearest neighbor algorithm support vector machin recurr neural network frequent occur schema algorithm abl leverag linguist pattern exampl score assign compet schema algorithm correl manual assign score spearman correl rang six nine schema set recurr neural network train separ schema outperform algorithm present result benchmark solut sinc conduct research explor possibl automat process qualit mental health data aim achiev optim perform explor model dataset thought record compris utter publish togeth articl research machin learn enthusiast improv upon outcom base promis result see opportun use free text input subsequ natur languag process common therapeut tool ecolog momentari assess autom case conceptu general altern mental health scale | D015928;D009323 | T066;T061 |
34,662,349 | stigma barrier address childhood trauma convers trauma survivor studi general popul victim childhood trauma report shame anticip stigma lead non disclosur avoid help stigma potenti aggrav mental health consequ childhood trauma far comprehens studi examin stigma toward adult survivor various form childhood trauma unclear whether stigma interfer reach affect individu vignett studi base repres sampl german general popul n male random alloc particip brief case vignett pertain past childhood sexualphys abus accid adult physic abus stigma elicit appli social distanc scale assess respond attitudesstereotyp toward person vignett reluct address specif trauma convers one aim establish preval stigma toward person ct hypothes attitud differ accord type trauma respond indic unlik reach victim childhood sexual abus victim childhood physic abus someon report childhood accid someon report adult physic abus contrari expect childhood sexual abus consist elicit stigma childhood physic abus krukal walli test equal childhood interperson trauma consist elicit stigma childhood accident trauma structur equat model reveal social distanc mediat relationship negat stereotyp reluct address childhood trauma convers analys reveal ambigu role negat stereotyp address childhood trauma convers trauma victim yet examin evid stigma associ surviv childhood trauma interf offer help | D012752;D057545 | T033;T041 |
34,662,347 | import age composit function profil human intestin microbiom intestin microbiom play central role human health diseas composit relat stabl throughout adulthood microbi balanc start decreas later life stage thus order maintain good qualiti life includ prevent age associ diseas elder import understand dynam intestin microbiom studi stool sampl particip sequenc whole metagenom shotgun sequenc taxonom function profil character two age group could separ base taxonom associ function featur use multivari associ linear model second approach machin learn biomark connect intestin microbiom age identifi result reflect import select age match studi group unbias metagenom data analysi possibl generat robust data appli independ algorithm data analysi furthermor sinc intestin microbiom modul antibiot probiot data studi may implic prevent strategi age associ degrad process diseas microbiom alter intervent | D000069196 | T007;T001 |
34,662,346 | mechanist model covid impact lockdown short time scale mitig spread covid coronavirus countri adopt stringent non pharmaceut intervent contrast wide use addit standard practic enforc curfew social distanc closur non essenti servic industri non convent polici also implement total lockdown fragment region compos spars high popul area | D000086382;D008954;D011790 | T047;T075;T061;T067 |
34,662,345 | qualit lysin crotonylom analysi ovarian tissu harmonia axyridi palla lysin crotonyl kcr newli discov posttransl modif ptm studi proteom level speci studi kcr femal fertil insect speci still lack harmonia axyridi palla well known benefici insect use natur biolog control agent aphid agricultur global kcr identif ovarian tissu h axyridi diapaus stage perform reveal potenti role kcr h axyridi ovarian cellular process femal fertil diapaus regul total kcr site protein identifi bioinformat analys reveal distribut protein multipl subcellular local categori involv divers biolog process metabol pathway carbohydr energi metabol relat cellular process includ citric acid cycl glycolysi oxid phosphoryl appear affect kcr modif addit regul translat protein biosynthesi may reflect kcr involv diapaus h axyridi kcr affect ribosom activ amino acid metabol moreov kcr modul h axyridi ovari develop regul may share common mechan kcr particip diseas progress process pathway uncov diapaus stage possibl enrichedspecif diapaus stage due limit qualit proteom experiment design result inform potenti kcr modif regul femal fertil insect physiolog | D008239;D011499 | T044;T116;T121;T123 |
34,662,344 | new framework base featur model ensembl learn predict queri perform queri optim attempt predict perform metric base amount time elaps theoret would necessit creation signific overhead core engin provid necessari queri optim statist machin learn increas use improv queri perform incorpor regress model predict respons time queri queri perform approach reli dbms optim statist cost estim oper queri execut plan also focus resourc util cpu io model queri featur thus critic step develop robust queri perform predict model paper propos new framework base queri featur model ensembl learn predict queri perform use framework queri perform predictor simul optim queri featur influenc queri perform queri featur model propos five dimens use model queri featur queri featur dimens syntax hardwar softwar data architectur histor perform log featur base develop train dataset perform predict model employ ensembl learn model result ensembl learn leverag queri perform predict problem deal miss valu handl overfit via regular section experiment work go use propos framework experiment work train dataset paper made perform data log various real world environ outcom compar show differ actual expect perform propos predict model empir work show effect propos approach compar relat work | D000069550 | T066 |
34,662,342 | factor affect aerosol sar cov transmiss via hvac system model studi role heat ventil air condit hvac system transmiss sar cov unclear address gap simul releas sar cov multistori offic build three social gather set barrestaur nightclub wed venu use well mix multi zone build model similar use well riley other vari key factor hvac system air chang per hour rate ach fraction outsid air foa minimum effici report valu merv examin effect viral transmiss addit simul protect effect unit ultraviolet light decontamin uvc separ room air filtrat build type increas ach reduc simul infect effect seen even low aerosol emiss rate howev benefit increas fraction outsid air filter effici rate greatest aerosol emiss rate high uvc filtrat improv perform typic hvac system room filtrat offic set similar reduc overal infect work better place everi room overal found littl evid hvac system facilit sar cov transmiss infect simul offic occur near emiss sourc infect individu temporarili visit releas zone hvac system increas infect one scenario involv margin increas airflow poor ventil space slight increas likelihood transmiss outsid releas zone found improv air circul rate increas filter merv rate increas fraction outsid air appli uvc radiat room filtrat may reduc sar cov transmiss indoor howev mitig measur unlik provid protect benefit unless sar cov aerosol emiss rate high plaqu form unit pfu min | D000389;D006361;D000086402;D014691 | T069;T005;T068;T067 |
34,662,341 | inform structur improv recal discharg inform cluster random clinic trial impact qualiti discharg communic physician patient critic patient health outcom nevertheless low recal inform given patient discharg emerg depart ed well document problem therefor investig outcom relat benefit two differ communic strategi physician instruct either use empathi e inform structur skill hypothes superior recal patient group | D003142;D010817 | T097;T080;T170;T054 |
34,662,340 | food biodivers total caus specif mortal european countri analysi prospect cohort studi food biodivers encompass varieti plant anim organ consum food drink intrins potenti underpin divers nutriti diet improv earth system resili dietari speci rich dsr recommend crosscut measur food biodivers posit associ micronutri adequaci diet women young children low middl incom countri lmic howev relationship dsr major health outcom yet assess popul | D044822;D002423;D005502;D009026 | T080;T168;T033;T081 |
34,662,337 | network potenti identifi therapeut mirna cocktail ewe sarcoma microrna mirna base therapi emerg class target therapeut mani potenti applic ewe sarcoma patient could benefit dramat person mirna therapi due inter patient heterogen lack druggabl point target howev broad effect mirna may differ cell tissu trial mirna therapi struggl due sever toxic unanticip immun respons order overcom hurdl network scienc base approach well equip evalu identifi mirna candid combin candid repress key oncogen target avoid repress essenti housekeep gene first character ewe sarcoma cell line use mrna sequenc estim measur tumor state term network potenti base mrna gene express under protein protein interact network tumor next rank mrna target base contribut network potenti identifi mirna combin mirna preferenti act repress mrna target greatest influenc network potenti analysi identifi trim app elav rnf hnrnpl ideal mrna target ewe sarcoma therapi use predict mirna mrna target map identifi mir p let p mir mir p let b p candid optim mirna preferenti repress target ultim work exemplifi case ewe sarcoma describ novel pipelin person mirna cocktail design maxim perturb gene network contribut cancer progress | D012333;D012512;D059467 | T191;T123;T114;T081;T086 |
34,662,335 | discret mechan model lamellipodi actin network implement molecular clutch mechan generat arc microspik mechan forc actin filament turnov adhes extracellular environ regul lamellipodi protrus comput mathemat model continuum level use investig molecular clutch mechan calcul stress profil lamellipodium around focal adhes howev forc deform individu actin filament consid interact actin network actin bundl easili account method develop filament level model lamellipodi actin network undergo retrograd flow use brownian dynam retrograd flow promot simul push forc lead edg due actin polymer pull forc due molecular motor oppos viscous drag cytoplasm focal adhes simul network densiti similar measur prior electron micrograph connect individu actin segment maintain perman dynam crosslink remodel network occur via addit singl actin filament near lead edg via filament bond sever investig sever paramet affect stress distribut network deform retrograd flow speed model captur decreas retrograd flow upon increas focal adhes strength stress profil chang compress extens across lead edg region filament bend around focal adhes model reproduc observ reduct retrograd flow speed upon exposur cytochalasin halt actin polymer chang crosslink concentr dynam well orient pattern newli ad filament demonstr model abil generat bundl filament perpendicular actin arc parallel microspik protrud direct | D008841;D008954;D011554 | T026;T075 |
34,662,333 | model epidemiolog impact unaid target end aid public health threat unaid establish new program target achiev goal elimin aid public health threat studi report effort use mathemat model estim impact achiev target | D060740;D014943;D006040;D008954;D008962;D011634 | T170;T078;T091;T075;T058;T062 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.